CURRICULUM VITÆ NAME: Cláudia Patrícia Martins Monteiro DATE OF BIRTH: January 13, 1981 PLACE OF BIRTH: Guarda, Portugal ADRESS: INEB-Instituto de Engenharia Biomédica, Universidade do Porto, Rua do Campo Alegre, 823, 4150-180 Porto, Portugal Email: claudia.monteiro@ineb.up.pt; alternative email: claudiapmm@gmail.com EDUCATION Present position Post-doctoral fellow at Instituto de Engenharia Biomédica (INEB). Supervisor: Dr. Cristina Martins. Project: Antimicrobial coatings based on chitosan-antimicrobial peptides for the prevention of bone implant-associated infection. Suported by a FCT post-doctoral fellowship. 2011 Post-doctoral fellow at the Karolinska Institute; Dept. of Microbiology, Tumor and Cell Biology (MTC). Supervisor: Dr. Ute Römling. Project in collaboration with the Royal Institute of Technology (KTH) and the company Svenska Cellulosa Aktiebolaget (SCA). Funded by Vinnova. January 2011 PhD defense, Karolinska Institutet, Stockholm, Sweden. Opponent: Professor Jean-Marc Ghigo, Institute Pasteur, Genetics of Biofilms Unit. 2006-2011 Postgraduate studies at Karolinska Institutet in the Dept of Microbiology, Tumour and Cell Biology (MTC), Stockholm, Sweden. Supervisor: Dr. Ute Römling; Co-supervisor: Dr. Sun Curriculum Vitæ Cláudia Monteiro 1
Nyunt Wai. Doctoral studies: Regulation of biofilm formation in Salmonella typhimurium and Escherichia coli Nissle 1917 Supported by an EU Marie Curie Fellowship for Early Stage Research Training. 2004-2005 Post-graduation in Cellular and Molecular Biology of the Dept. of Biology of the University of Coimbra. Research Technician at the Center for Neuroscience and Cell Biology of the University of Coimbra. Developed project: Genetic studies in Portuguese patients with Familiar Hypertrophic Cardiomiopathy. Project Manager: Prof. Dr. Carlos Faro. 2003-2004 Research Training at the Genetic Forensic Service of the Institute of Legal Medicine, Coimbra under the supervision of Dr. Maria da Conceição Vide, director of the service of Genetic and Forensic Biology of the same Institute. Thesis Title: Studies of STRs of the Y - chromosome and regions HVI and HVII of the mitochondrial DNA in a Brazilian Population São Paulo. (grade of 19, scale 0-20). 1999-2004 Biochemistry degree from the Dept of Biochemistry of the University of Coimbra. July 1999 Finished High Scholl at the Escola Secundária da Sé, Guarda. PUBLICATIONS 1. C Monteiro, K Papenfort, K Hentrich, I Ahmad, S Le Guyon, R Reimann, Grantcharova N, Römling U. Hfq and Hfq-dependent small RNAs are major contributors to multicellular development in Salmonella enterica serovar Typhimurium. RNA Biol. 2012 Apr 1; 9(4). [Epub ahead of print] 2. C Monteiro, X Fang, I Ahmad, M Gomelsky, and U Römling. Regulation of Biofilm Components in Salmonella enterica Serovar Typhimurium by Lytic Transglycosylases Involved in Cell Wall Turnover. J Bacteriol. 2011 Dec;193(23):6443-51. Curriculum Vitæ Cláudia Monteiro 2
3. N Grantcharova, V Peters, C Monteiro, K Zakikhany, U Römling. Bistable Typhimurium. Journal of Bacteriology. 2010 Jan;192(2): 456-66. 4. A Lamprokostopoulou, C Monteiro, M Rhen, U Römling. Cyclic di-gmp signalling controls virulence properties of Salmonella enterica serovar Typhimurium at the mucosal lining. Environmental Microbiology. 2010 Jan; 12(1): 40-53. 5. C Monteiro, I Saxena, X Wang, A Kader, W Bokranz, R Simm, D Nobles, M Chromek, A Brauner, R Brown, U Römling. Characterization of cellulose production in Escherichia coli Nissle 1917 and its biological consequences. Environmental Microbiology. 2009 May;11(5):1105-16. ORAL PRESENTATIONS 1- N Grantcharova, V Peters, C Monteiro, K Zakikhany, U Römling. Bistable Typhimurium. 4th Annual Meeting of IRTG1273 - International Research Training Group 1273 Strategies of human pathogens to achieve acute and chronic infections, Stockholm, Sweden, November 3, 2009. 2- Role of cellulose production in the probiotic Escherichia coli Strain Nissle 1917: C.Monteiro, X.Wang, D.Nobles, R.M.Brown and U.Römling. Infection Biology Student Conference, Stockholm, Sweden, January 28, 2009. POSTERS 1- N Grantcharova, V Peters, C Monteiro, K Zakikhany, U Römling. Bistable Typhimurium. On-site Review of the International Research Training Group 1273 Strategies of human pathogens to achieve acute and chronic infections. TWINCORE Institute for Experimental and Clinical Infection Research, Hannover, Germany. September 1, 2010. 2- C. Monteiro, M. Gomelsky, U. Römling. Role of Lytic Transglycosylases in Rdar morphotype expression in Salmonella Typhimurium. MTC Annual Talks 2010, Nobel Fórum, KI, Stockholm, Sweden. 3- N Grantcharova, V Peters, C Monteiro, K Zakikhany, U Römling. Bistable Typhimurium. Symposium on Bacterial Cell Biology and Pathogenesis & Workshop on Microscopy in Microbial Systems. Umeå University, Umeå, Sweden. June 14 to 18, 2009. Curriculum Vitæ Cláudia Monteiro 3
4- Role of cellulose production in the probiotic Escherichia coli Strain Nissle 1917: C.Monteiro, X.Wang, D.Nobles, R.M.Brown and U.Römling. 4th National Infection Biology meeting, Malmö, Sweden, November 13 to 14, 2008. 5- The role of cyclic di-gmp in virulence phenotypes of Salmonella enterica serovar Typhimurium; A.Lamprokostopoulou, C.Monteiro, R.Simm, and U.Romling. American Society For Microbiology 108th General Meeting June 1-5, 2008 In Boston, Massachusetts. 6- Role of cellulose production in the probiotic Escherichia coli Strain Nissle 1917: C.Monteiro, X.Wang, D.Nobles, R.M.Brown and U.Römling. Joint Symposium for International Association on Gnotobiology & Society for Microbial Ecology & Disease Stockholm, Sweden May 28-30, 2008. 7- The role of cyclic di-gmp in virulence phenotypes of Salmonella enterica serovar Typhimurium; A.Lamprokostopoulou, C.Monteiro, R.Simm, and U.Romling. Joint Symposium for International Association on Gnotobiology & Society for Microbial Ecology & Disease Stockholm, Sweden May 28-30, 2008. 8- The role of cyclic di-gmp in virulence phenotypes of Salmonella enterica serovar Typhimurium; A.Lamprokostopoulou, C.Monteiro, R.Simm, and U.Romling. 3 rd National Infection Biology Meeting in Upsalla, Sweden, November 15-16, 2007. 9- The Y-chromosome in Portuguese speaking populations; Brito P, Monteiro C, Cainé L, Carval OM, Balsa F, Anjos MJ, Andrade L, Lopes V, Serra A, Gamero JJ, Corte-Real F, Vide MC. IV Research in Medicine Meeting, 17 and 18 November 2004, Coimbra, Portugal. 10- Minimal Haplotype Analysis of the Y-Chromosome in two Brazilian Populations: São Paulo and Amazonas; Monteiro C, Brito P, Carvalho M, Balsa F, Anjos MJ, Andrade L, Lopes V, Serra A, Gamero JJ, Corte-Real F, Vide MC. IX Genetic Forensic Journies, Meeting of ISFG Spanish and Portuguese Groups, 2-4 June 2004, Manaus, Brazil. AWARDS 2011 Granted a post-doctoral fellowship by the Portuguese Science and Technology Foundation. 2006 Granted a Marie Curie Early Stage Research Training Fellowship of the European Community s Sixth Framework Programme. Curriculum Vitæ Cláudia Monteiro 4
PARTICIPATION IN INTERNATIONAL COLLABORATIONS Participated in the International Research Training Group 1273 Strategies of human pathogens to achieve acute and chronic infections. Institutions involved: MHH Hannover Medical School, Germany MHH-HBRS Hannover Biomedical Research School, Germany Helmholtz Center for Infection, Braunswcheig, Germany TWINCORE, Hannover, Germany Karolinska Institutet, Stockholm, Sweden Smittskyddsinstitutet The Swedish Institute for Infectious Disease Control, Stockholm, Sweden Other collaborations: Professor R. Malcolm Brown Jr., University of Texas at Austin, USA Dr. Mark Gomelsky, Wyoming University, USA Professor Jörg Vogel, Max Plank Institute for Infection Biology TEACHING EXPERIENCE Supervised one Master thesis student and two internship students during PhD studies and one internship student during post-doc. CONGRESSES AND CONFERENCES 2010 MTC Annual Talks 2010, Nobel Forum, Karolinska Institutet, Stockholm, Sweden. On-site Review of the International Research Training Group 1273 Strategies of human pathogens to achieve acute and chronic infections. TWINCORE, Hannover, Germany. 2009 Infection Biology Student Conference, Stockholm, Sweden, January 28, 2009. Symposium on Bacterial Cell Biology and Pathogenesis & Workshop on Microscopy in Microbial Systems. Umeå University, Umeå, Sweden, June 14 to 18, 2009. Curriculum Vitæ Cláudia Monteiro 5
4 th Annual Meeting of the International Research Training Group 1273 Strategies of human pathogens to achieve acute and chronic infections. Stockholm, Sweden. 2008 Joint Symposium for International Association on Gnotobiology & Society for Microbial Ecology & Disease Stockholm, Sweden May 28-30, 2008. American Society for Microbiology 108th General Meeting June 1-5, 2008 In Boston, Massachusetts. 4th National Infection Biology meeting, Malmö, Sweden, November 13 to 14, 2008. 2007 3 rd National Infection Biology Meeting in Upsalla, Sweden, November 15-16. 2006 KI Infection Retreat 2-5 February 2006 2-5 February 2006 at Trysil, Norway (attended). 2004-2005 Molecular Cell Biology Lectures, November 18-22, IBILI, Coimbra, Portugal (personal interest). 2003 I National Meeting of Biochemistry Students, April 25-27, Coimbra, Portugal. 2002 XIII National Biochemistry Congress, 5-7 December, Lisboa, Portugal. Molecular Cell Biology-lectures, November 18-22, IBILI, Coimbra, Portugal (personal interest) 2001 II Professional Journeys, by ANBIOQ (National Association of Biochemistry), October 1-3, Coimbra University 2000 XII National Meeting of Biochemistry, September 28-30, Póvoa do Varzim, Portugal (personal interest) POST-GRADUATE EDUCATION Courses taken at Karolinska Institutet Laboratory Animal Science (granted official certificate for work using laboratory animals) To Communicate Science Writing Science Philosophy of Science Basic Course in Medical Statistics A molecular ticket to enter the cell the ubiquitin-proteasome system in intracellular trafficking Curriculum Vitæ Cláudia Monteiro 6
Host-microbe interactions research seminar series Inflammation and Immunity in microbe-mucosa interactions Clinical Immunology in Infectious disease Other activities Visit to another laboratory Six weeks visit to a laboratory in the Department of Molecular Biology in the University of Umeå, Sweden, under the supervision of Professor Sun Nyunt Wai. The purpose of this visit was to learn how to work with C. elegans and perform virulence experiments with bacteria using C.elegans as host. Symposiums and workshops: Quantitative and systems biology in the host-parasite interactions (workshop) Microbial biofilms in vivo (Mini-symposium) Workshop on Microscopy in Microbial Systems. Umeå University, Umeå, Sweden. LANGUAGE SKILLS ENGLISH Very Good Knowledge; B1 Alte Level 2 successfully completed in the International House Scholl. Basic knowledge in French and Spanish. Curriculum Vitæ Cláudia Monteiro 7