1150 W. Medical Center Dr. Research Investigator Ann Arbor, MI Department of Microbiology and Immunology phone: (734)

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1 Alteri, Christopher J Medical Science Bldg. II 1150 W. Medical Center Dr. Research Investigator Ann Arbor, MI Department of Microbiology and Immunology phone: (734) University of Michigan Medical School Education B.S., University of Arizona, Tucson, AZ Microbiology and Chemistry, Dec Ph.D., University of Arizona, College of Medicine, Tucson, AZ Microbiology and Immunology, Aug Postdoctoral Training Research Fellow, Laboratory of Harry L.T. Mobley, Ph.D. Department of Microbiology and Immunology University of Michigan Medical School, Ann Arbor, MI Research Interests Grants 1. The role of bacterial nutrition and metabolism during bacterial infections. 2. Urinary tract infections caused by Escherichia coli and Proteus mirabilis. 3. Polymicrobial interactions during urinary tract infection Extramural Clinical Research Loan Repayment Program National Institutes of Health. Honors and Awards E. Ray Cowden College of Agriculture Scholarship, University of Arizona, consecutive awards Undergraduate Mentor Program in Research Education Participant and grant recipient, University of Arizona Undergraduate Research Grant, University of Arizona, Honors College Graduate Scholarship Award, University of Arizona College of Medicine, Department of Microbiology and Immunology, Tucson, AZ Student Presentation Award, AZ-NV American Society for Microbiology annual branch meeting, Tucson, AZ Richard and Mary Finkelstein Award, American Society for Microbiology 104 th General Meeting, New Orleans, LA Postdoc Leadership Mentoring Award, Alfred P. Sloan Foundation, National Postdoctoral Association Annual Meeting, Berkeley, CA.

2 2008 Travel Award, National Cancer Institute/Center for Cancer Research, National Postdoctoral Association Annual Meeting, Boston, MA. Professional Societies Teaching American Society for Microbiology, 2001-present. National Postdoctoral Association Laboratory training for Patrick Vigil, Medical Scientist Training Program student, University of Michigan Medical School Laboratory training for Daniel Reiss, Medical Scientist Training Program student, University of Michigan Medical School Lecturer for MIC 607 Host-Pathogen Relationships Module. Course Director: Phil Hanna, Ph.D Instructor BIOMED 490, Biomedical Engineering Directed Research, University of Michigan Medical School, Department of Microbiology and Immunology Lecturer and Course Director for MICRO 485 Microbial Physiology. University of Michigan, Department of Natural Sciences, Dearborn, MI Lecturer and Course Director for MICRO 405/505 Applied and Environmental Microbiology. University of Michigan, Department of Natural Sciences, Dearborn, MI Lecturer and Course Director for MICRO 485 Microbial Physiology. University of Michigan, Department of Natural Sciences, Dearborn, MI. Professional Service and Committees Institutional 2008 Search committee, Assistant Dean for Graduate and Postdoctoral Studies, University of Michigan Medical School President, University of Michigan Postdoctoral Association National Postdoctorate Leaders Resource Committee, Association of American Medical Colleges Postdoctoral Liason; Group on Graduate Research, Education, and Training (GREAT) Postdoctorate Leaders Section, Association of American Medical Colleges AAMC GREAT Postdoc Section Annual Meeting Program Committee

3 Invited Presentations 2008 Preparing Future Faculty Conference. University of Michigan Rackham School of Graduate Studies Preparing Future Faculty Conference. University of Michigan Rackham School of Graduate Studies Microbiology and Immunology Annual Retreat. University of Michigan Medical School Department of Microbiology and Immunology Invited Speaker, Infection and Immunity Workshop. University of Toledo Department of Medical Microbiology, Toledo, OH Invited Seminar, Wayne State University College of Medicine, Immunology and Microbiology Department, Detroit, MI Microbiology and Immunology Seminar Series, University of Michigan Medical School Department of Microbiology and Immunology Invited Speaker, American Society for Microbiology General Meeting, New Orleans, LA. Patents R.L. Friedman, J.A. Giron, and C.J. Alteri. Pili from Mycobacterium tuberculosis. February 9, /543,109 and 60/548,899 U.S. Patent and Trademark Office. Bibliography Peer-reviewed Journal Publications 1. Brown, J.K., A.M. Idris, C. Alteri and D.C. Stenger Emergence of a new cucurbit-infecting begomovirus capable of forming viable reassortants with related viruses in the Squash leaf curl virus cluster. Phytopathology 92: C. J. Alteri, J. Xicohténcatl-Cortes, S. Hess, G. Caballero-Olin, J.A. Giron, and R.L. Friedman Mycobacterium tuberculosis produces pili during human infection. Proc. Natl. Acad. Sci. USA Mar 20;104(12): *Highlighted in Science Editor s Choice Mar **Cited in Faculty of ***Highlighted in Nature Reviews Microbiology 5, 328 (May 2007). 3. C.J. Alteri and H.L.T. Mobley Quantitative profile of the uropathogenic Escherichia coli outer membrane proteome during growth in human urine. Infect. Immun. Jun;75(6): *Selected in Infection and Immunity Editor s Spotlight Jun M.C. Lane, C.J. Alteri, S.N. Smith, and H.L.T. Mobley Expression of flagella is coincident with uropathogenic Escherichia coli ascension to the upper urinary tract. Proc. Natl. Acad. Sci. USA Oct 16;104(42): *Cited in Faculty of C.J. Alteri, S.N. Smith, and H.L.T. Mobley Fitness of Escherichia coli during Urinary Tract Infection Requires Gluconeogenesis and the TCA Cycle. PLoS Pathog. May; 5(5):e *Cited in Faculty of 1000.

4 6. C.J. Alteri, E.C. Hagan, K.E. Sivick, S.N. Smith, and H.L.T. Mobley Mucosal immunization with iron receptor antigens protects against urinary tract infection. PLoS Pathog. Sep; 5(9):e *Highlighted in Nature Reviews Microbiology 7, 764 (November 2009). 7. P. Vigil, C.J. Alteri, and H.L.T. Mobley Identification of in vivo induced antigens including a RTX family exoprotein required for uropathogenic Escherichia coli virulence. Infect. Immun. Mar 21, 2011 [Epub ahead of print] Abstracts 1. Novel pili of Mycobacterium tuberculosis Oral presentation presented at AZ-NV American Society for Microbiology annual branch meeting. Tucson, AZ. 2. Novel pili of mycobacteria Oral presentation, published abstract, and poster presented at 104 th American Society for Microbiology General Meeting, New Orleans, LA. 3. C.J. Alteri, R.L. Friedman, and J.A, Girón. Mycobacterium tuberculosis produces amyloid surface fibers involved in bacterial adherence Published abstract and poster presented at 44 th Annual ICAAC, Washington D.C. 4. C.J. Alteri, S. Hess, G. Caballero-Olín, J.A. Girón, and R.L. Friedman. Production of pili is widespread among mycobacteria: Novel Insight into mycobacterial physiology and pathogenesis Published abstract and poster presented at Keystone Symposia, Tuberculosis: Integrating Host and Pathogen Biology, Whistler, B.C. CANADA. 5. C.J. Alteri and H.L.T. Mobley. Identification of adaptive uropathogenic Escherichia coli features that facilitate growth in human urine Published abstract and poster presented at the American Society for Microbiology 106 th General Meeting, Orlando, FL. 6. M.C. Lane, C.J. Alteri, and H.L.T. Mobley. Expression of flagella is coincident with upper urinary tract infection abstract and poster presented at the Global Infectious Disease Symposia, Ann Arbor, MI. 7. M.C. Lane, C.J. Alteri, and H.L.T. Mobley. Expression of flagella is coincident with uropathogenic Escherichia coli ascension to the upper urinary tract Published abstract and poster presented at the American Society for Microbiology 107 th General Meeting, Toronto, ON CANADA. 8. C.J. Alteri, P.D. Vigil, and H.L.T. Mobley. Identification of uropathogenic Escherichia coli genes expressed during urinary tract infection using in vivoinduced antigen technology (IVIAT) Published abstract and poster presented at the American Society for Microbiology 107 th General Meeting, Toronto, ON CANADA. 9. K.E. Sivick, E. Hagan, C. Alteri, M. Schaller, and H.L.T. Mobley. Immunological correlates of protection in mice intranasally vaccinated against uropathogenic Escherichia coli. Published abstract and poster presented at the American Society for Microbiology 108 th General Meeting, Boston, MA. 10. E.C. Hagan, C.J. Alteri, K.E. Sivick, S.N. Smith, and H.L.T. Mobley. Immunization with outer membrane iron receptors protects against uropathogenic Escherichia coli infection. Published abstract and poster presented at the American Society for Microbiology 108 th General Meeting, Boston, MA. 11. C.J. Alteri, D.J. Reiss, and H.L.T. Mobley. Systematic analysis of uropathogenic Escherichia coli metabolism during growth in human urine. Published abstract and

5 poster presented at the American Society for Microbiology 108 th General Meeting, Boston, MA. 12. S.D. Himpsl, C.J. Alteri, and H.L.T. Mobley. Metabolic requirements for bacterial pathogenesis within the urinary tract. Published abstract and poster presented at the American Society for Microbiology 110 th General Meeting, San Diego, CA. 13. C.J. Alteri, J.R. Lindner, and H.L.T. Mobley. Escherichia coli requires phop for virulence during urinary tract infection. Published abstract and poster presented at the American Society for Microbiology 110 th General Meeting, San Diego, CA.