NIRCal Software data sheet



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NIRCal Software data sheet NIRCal is an optional software package for NIRFlex N-500 and NIRMaster, that allows the development of qualitative and quantitative calibrations. It offers numerous chemometric algorithms, data pre-treatment and visualization tools to analyze your spectroscopic data. The patented Calibration Wizard automates the creation and optimization of precise and robust calibration models.

System requirements The PC must fulfill the following requirements: Operating System Central Processing Unit RAM Harddisk Windows 7 Professional / Enterprise / Ultimate (64-bit) SP1, 3 GB RAM Windows 8 Pro (64-bit),.NET 3.5 recommended, 3 GB RAM Intel Core i3 or higher and 1.4 GHz or faster 3 GB or higher 15 GB free hard disk space Display resolution 1280 x 1024 LAN Others 1 x 100 Mbit/s LAN (2 x 100 Mbit/s LAN recommend) DVD-ROM drive Licenses NIRCal NIRCal Toolbox NIRCal chemometric software, including the Calibration Wizard (registration required) The Toolbox provides quick and easy access to the essential parameters, simplifying method development (specific license required) Order code Choose the configuration according to your needs: N 5 5 0 0 21 NIRCal 5 Chemometric Software CD incl. License 23 NIRCal 5 Chemometric Software CD - 3 Licenses 41 NIRCal Toolbox 1 CD incl. License (requires NIRCal) 42 NIRCal Toolbox 1 CD - 3 Licenses (requires NIRCal) 2

Functional principle Workflow The following table depicts the typical workflow from data generation over calibration development to routine use. This workflow is compliant to Pharmaceutical guidelines for NIR application s lifecycle. Task Lifecycle NIRWare Operator NIRWare Management Console NIRCal Setup reference application Set application to approved Record spectra of reference samples Define sample properties and values Calibrate Set calibration to approved Copy application as template for routine use Define SOP Assign calibration to application Set application to approved Use for prediction / routine measurement 3

Description Chemometrics Multivariate quantitative and qualitative (classification, identification) calibration methods PLS, PCR, MLR, CLUSTER and SIMCA. Multivariate data analysis with PCA. Large selection of 45 data preprocessing algorithms (pretreatments) that can be used in any sequence, e. g. normalization, SNV, derivatives (1st/ 2nd/ 3rd), smoothing, transformations, offset correction, MSC, custom linear filtering. Data Visualization Interactive graphical visualization of spectral data, chemometric parameters and results in different plot types: line plot, parallel coordinates plot, scatter plot, surface plot in 1D, 2D and 3D. Interactive zooming, panning, scrolling, rotating, resizing, coloring, visibility and data info tooltips. selected spectra are automatically highlighted in all plots simultaneous selection of wavelengths Easy selection of data sets (e.g. spectra, properties, wavelength, principal components) in graphic and table view. Live update of selected data within all corresponding plots and tables. Broad variety of visualization tools, like overview or dependency plots (e.g. data versus time, creator, instrument, property). Rapid calculations of large data sets. NIRCal provides context sensitive menus, customizable workspaces and toolbars. 4

NIRCals graphical engine provides powerful visualization tools like anti-aliasing and alpha-blending. Efficient review of big and complex data sets. Interactive 3D views (free rotation, zoom, selection and more) Example: Score plot to calibrate cluster models. Calibration Wizard Patented Calibration Wizard for automated calibration design based on BUCHI s long term application expertise. Optimized results through automated outlier detection, selection of suitable algorithms and wavelengths, etc. Wizard use requires just a few basic settings 5

NIRCal Toolbox The NIRCal Toolbox is a compact cockpit view of the most relevant NIRCal calibration parameters enhancing method development productivity. NIRCal data views are automatically updated when calibrations are modified in the NIRCal toolbox. Editable bar diagrams All essential settings summarized and editable in one view One-click switching allows immediate comparison of calibration versions Data Exchange NIRCal is compatible with a wide variety of data formats such as JCAMP-DX (jdx, dx), GRAMS (spc), MATLAB (dat), EXCEL (xls) and ASCII (csv) Reporting and Method Validation Support Detailed Calibration Protocol including settings, prediction results, outliers, used spectra, etc. Documented method verification and full traceability of changes and versions. 6

www.buchi.com/nir Quality in your hands NIRCal Software data sheet en 1312 B / Technical data are subject to change without notice / Quality Systems ISO 9001 The English version is the original language version and serves as basis for all translations into other languages.