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International Diploma Supplement Biology & Medical Laboratory Research Molecular Biology This Diploma Supplement follows the model developed by the European Commission, Council of Europe and UNESCO/CEPES. The purpose of the supplement is to provide sufficient independent data to improve the international 'transparency' and fair academic and professional recognition of qualifications (diplomas, degrees, certificates etc.). It is designed to provide a description of the nature, level, context, content and status of the studies that were pursued and successfully completed by the individual named on the original qualification to which this supplement is appended. It should be free from any value judgements, equivalence statements or suggestions about recognition. Information in all eight sections should be provided. Where information is not provided, an explanation should give the reason why. 1 Information identifying the holder of the qualification 1.1 Family name Janssen 1.2 Given name(s) Pieter Cornelis 1.3 Date and place of birth 10 October 1971, Antwerpen, Belgium 1.4 Student identification number 1234567 2 Information identifying the qualification 2.1 Name of qualification Bachelor of Applied Science (B AS) Title conferred The bachelor's degree gives the person concerned the right to express the degree in his name, abbreviated to B AS after the name of the person. In addition, the person concerned is allowed to use the title of ingenieur, abbreviated to ing. in front of the name. 2.2 Main field of study for the qualification Biologie en Medisch Laboratoriumonderzoek (Biology & Medical Laboratory Research); specialisation Molecular Biology 2.3 Name and status of awarding institution Hogeschool Utrecht (HU University of Applied Sciences Utrecht); state recognized 2.4 Name and status of institution administering studies Hogeschool Utrecht (HU University of Applied Sciences Utrecht); state recognized 2.5 Language of instruction/examination Dutch S PECIMEN page 1 of 9

3 Information on the level of qualification 3.1 Level of qualification Bachelor's Degree; University of Applied Sciences; First cycle National Qualifications Framework for Higher Education. 3.2 Official length of the programme Four years, 240 ECTS credits 3.3 Access requirements Admission to the Bachelor's degree course will be granted to any student in possession of a VWO, HAVO or MBO level 4 diploma (see paragraph 8) or an equivalent which will depend on the judgement of the Board of Examiners. For more information see chapter 8 "Higher education in the Netherlands" 4 Information on the contents and results gained 4.1 Mode of study Part-time, including internship(s) 4.2 Programme Requirements At the end of the course, students will be able: To conduct research as a researcher/analyst within the Research & Development domain (R&D) in a biological/medical field with the aim of developing new or improve existing products, methods or processes. To conduct research in diagnostic laboratories within Medical Laboratory Diagnostics (MLD) on human (or occasionally animal) tissue to contribute to answering clinical questions by applying analytical methods for the diagnosis, treatment and prevention of diseases. To conduct research independently or within a (multi-disciplinary) team to contribute to solving a complex biological/medical problem and to justify the research strategy chosen. To independently translate a request into a proper experiment, to carry out the experiment systematically in an efficient way to enable demonstrable reliable results to be obtained, taking into consideration quality assurance, safety, health, wellbeing, the environment, sustainability and ethics. To independently select and acquire (scientific) literature, and to correctly assess the reliability of the various information sources. To apply the correct (statistical) techniques to process and/or validate research results, to interpret research results and to provide both oral and written reports according to the appropriate domain-specific standards, and to draw conclusions and propose follow-up studies. To develop, implement and/or maintain domain-specific management systems or components of these systems and to tailor one s own activities to the management systems used in the workplace. To be employed within the Commerce, Service and Service Provision domain as a junior product specialist, advisor or trainer, or employed in product, system, services and equipment sales relating to biological and/or medical principles or systems. To translate technical aspects of biological and/or medical products and processes to users and vice versa. To reflect on one's own personal performance, to draw conclusions from this and to take action to guide oneself in terms of performance and development. page 2 of 9

4.3 Programme details and the individual grades/credits obtained Course date grade ECTS credits First year VD 60 DL3 Communication 04/01/2008 V 5 Biochemistry (Proteins) 04/10/2008 8 3 Externally Attained Competences 2 06/01/2008 7 5 Immunology 06/16/2008 8 4 Study And Career Development 3rd Semester 06/01/2008 V 1 Tutorial Biology 04/01/2008 9 3 Skills Training (Proteins) 06/15/2008 V 3 Statistical Methods (SPSS) 04/01/2008 8 3 Histology 06/17/2008 9 3 Previously Acquired Skills 2 11/15/2008 7 6 Previously Acquired Skills 1 01/01/2009 8 5 Orientation Training In Microbiology 11/15/2008 V 3 Molecular Biological Techniques 01/05/2009 8 3 Introduction In Molecular Biology 10/20/2008 8 3 Human Physiology 1 10/01/2008 6 3 Human Physiology 2 01/26/2009 7 3 Study And Career Development 4th Semester 02/02/2009 V 1 Recombinant DNA Skills 12/16/2008 8 3 Management Training 06/01/2009 V 2 Genomics/proteomics 06/01/2009 8 3 page 3 of 9

Course date grade ECTS credits Human Physiology 3 03/23/2009 7 3 Study Career Policy 5th Semester 06/08/2009 V 1 Skills Training In Cell Culture 06/01/2009 8 2 Bio-informatics 04/01/2009 V 3 Externally Attained Competences 1 06/01/2009 8 8 Externally Attained Competences 2 06/01/2009 8 5 Gene Expression Systems 06/15/2009 8 3 Cell Biology 2 10/26/2009 9 3 Cell Biology 3 01/04/2010 8 2 Professional Competences (A And B) 01/06/2010 8 15 Study And Career Development 6th Semester 01/27/2010 V 1 Virology Research 10/13/2009 7 3 Practical Skills in Mol. Diagnostics 10/15/2009 8 3 Practical Skills In Molecular Biology 01/07/2010 7 3 Study And Career Development 6th Semester 02/18/2010 V 1 Internship 09/17/2010 VRY 30 Graduation assignment(s) Presentation And Defence 04/08/2011 8 2 Theoretical Aspects Final Thesis 04/08/2011 8 6 Practical Aspects And Results 04/08/2011 9 15 Report Final Thesis 04/08/2011 9 6 The dates are given in the format month/day/year Total ECTS-credits 240 page 4 of 9

4.4 Grading scheme and grade distribution The Dutch grading system, used from elementary through university education is the 1 to 10 scale given in the following table, in which 10 is the highest grade, 6 the minimum pass, and 1 the lowest grade. 9s are seldom given and 10s are extremely rare, grades 1-3 are hardly ever given. Also alphanumerical grades can be awarded and are described below. Official Dutch numeric grading scheme: Alphanumeric grading scheme of the institution: Grade Description Grade Description 10 Excellent U Excellent 9 Very good ZG Very Good 8 Good G Good 7 Satisfactory RV Satisfactory 6 Sufficient V Sufficient 5-1 Fail VD Complete VRY Exemption For more information see chapter 8 "Higher education in the Netherlands" 4.5 Overall classification of the qualification Cum Laude geslaagd This Bachelor's degree is granted with the qualification "cum laude". The qualification "cum laude" can be granted to a Bachelor's degree when the student has met all the requirements of article 44 of the Teaching and Examination Regulation. 5 Information on the function of the qualification 5.1 Access to further study Bachelor's degree programmes may entitle access to second cycle studies (Master programmes) For more information see chapter 8 "Higher education in the Netherlands" 5.2 Professional status No further qualification required for pursuing a professional career. page 5 of 9

6 Additional information about the institution 6.1 The programme is accredited on the 1st August 2005 by the Netherlands- Flemish Accreditation Organisation (NVAO: Nederlands-Vlaamse Accreditatie Organisatie) 6.2 Hogeschool Utrecht P.O. Box 573 3500 AN Utrecht the Netherlands http://www.hu.nl 7 Certification of the supplement 7.1 Date 8 April 2011 7.2 Signature 7.3 Certifying person Chairman of the board of examiners Drs. C.Y. Barendsen 7.4 Official stamp page 6 of 9

8 Information on the national higher educational system Primary education lasts eight years (of which seven are compulsory), in the last year of which pupils are advised as to the type of secondary education they should pursue. Secondary education, which begins at the age of 12 and is compulsory until the age of 16, is offered in several types at several levels. VMBO programmes (four years) combine general and vocational education, after which pupils can continue in senior secondary vocational education and training (MBO) lasting one to four years. The two programmes of general education that grant admission to higher education are HAVO (five years) and VWO (six years). Pupils are enrolled according to their ability. The last two years of HAVO and the last three years of VWO are referred to as the tweede fase (literally, second phase), or upper secondary education. During these years, pupils focus on one of four subject clusters (profielen), each of which emphasizes a certain field of study in addition to satisfying general education requirements. Each cluster is designed to prepare pupils for programmes of study at the tertiary level. A pupil enrolled in VWO or HAVO can choose from the following subject clusters: 1. Science and Technology (Natuur en Techniek) 2. Science and Health (Natuur en Gezondheid) 3. Economics and Society (Economie en Maatschappij) 4. Culture and Society (Cultuur en Maatschappij) Only the six year VWO diploma grants access to the bachelor programmes offered by research universities; the HAVO diploma and the highest level of MBO grant access to the bachelor programmes offered by universities of applied sciences. Higher education: As a result of the Bologna process, the higher education system in the Netherlands is organised around a threecycle degree system, consisting of bachelor's, master's and PhD degrees. Two types of programmes are offered in higher education: research oriented degree programmes offered primarily by research universities, and professional higher education programmes offered primarily by universities of applied sciences. Higher education in the Netherlands is offered at two types of institution: research universities and universities of applied sciences. Research universities include general universities, universities specializing in engineering and agriculture, and the Open University. Universities of applied sciences include general institutions as well as institutions specializing in a specific field such as agriculture, fine and performing arts, or teacher training. Whereas research universities are primarily responsible for offering research-oriented programmes, universities of applied sciences are primarily responsible for offering programmes of higher professional education, which prepare students for particular professions. These tend to be more practically oriented than programmes offered by research universities. In this binary and three-cycle system, bachelor's, master's and PhD degrees are awarded. Short-cycle higher education leading to the Associate degree is offered by universities of applied sciences. Degree programmes and periods of study are quantified in terms of the ECTS credit system. The focus of degree programmes determines both the number of credits required to complete the programme and the degree which is awarded. A research-oriented bachelor's programme requires the completion of 180 credits (3 years) and graduates obtain the degree Bachelor of Arts or Bachelor of Science (BA/BSc), depending on the discipline. A bachelor's degree awarded in the applied arts and sciences requires the completion of 240 credits (4 years), and graduates obtain a degree indicating the field of study (for example, Bachelor of Engineering, B Eng, or Bachelor of Nursing, B Nursing). An associate's degree in the applied arts and sciences requires the completion of 120 credits (2 years), and students who complete the 2-year programme can continue studying for a bachelor's degree in the applied arts and sciences. A research-oriented master's programme requires the completion of 60, 90, or 120 credits (1, 1.5, or 2 years). In engineering, agriculture, and math and the natural sciences, 120 credits are always required. Graduates obtain the degree of Master of Arts or Master of Science (MA/MSc). A master's degree awarded in the applied arts and sciences requires the completion of 60 to 120 credits and graduates obtain a degree indicating the field of study (for example, Master of Architecture, M Arch). The third cycle of higher education, leading to the PhD, is offered only by research universities. The major requirement is completion of a dissertation based on original research that is publicly defended. All research universities award the PhD. In addition to the doctorate, the three engineering universities offer (technological) designer programmes consisting of advanced study and a personal design assignment in a number of engineering page 7 of 9

fields. The technological designer programme requires two years of study to complete and graduates obtain the degree "Professional Doctorate in Engineering (PDEng)". The training of medical specialists is the responsibility of the professional group in an organisational setting at a university hospital. Requirements for Access to Higher Education: For access to research-oriented bachelor's programmes, students are required to have a VWO diploma or to have completed the first year (60 credits) of a bachelor's programme at a university of applied sciences. The minimum access requirement to universities of applied sciences is either a HAVO diploma or a diploma of secondary vocational education (MBO diploma), provided certain conditions are met. The VWO diploma also grants access to universities of applied sciences. For access to both types of higher education, pupils are required to have completed at least one of the subject clusters that fulfils the requirements for the higher education programme in question. A quota, or numerus fixus, applies for access to certain programmes, primarily in the medical sciences, and places are allocated mainly using a weighted lottery. Potential students older than 21 years of age who do not possess one of the qualifications mentioned above can qualify for access to higher education on the basis of an entrance examination and assessment (recognition of prior learning). For access to certain programmes, particularly those in the fine arts, students have to demonstrate the required artistic abilities. The only access requirement for the Open University is that applicants be at least 18 years of age. For access to all master's programmes, a bachelor's degree in one or more specified disciplines is required, in some cases in combination with other requirements. Graduates with a bachelor's degree in the applied arts and sciences may have to complete additional requirements for access to a researchoriented master's degree programme. Credit System and Grading: A student's workload is measured in ECTS credits. According to Dutch law, one credit represents 28 hours of work and 60 credits represents one year of full-time study. The grading system used in the Netherlands is on a scale from 1 (very poor) to 10 (outstanding). The lowest passing grade is 6; 9s are seldom given and 10s are extremely rare and grades 1-3 are hardly ever used. The academic year is 42 weeks long. Quality Assurance and Accreditation: A guaranteed standard of higher education, and alignment with the Qualifications Framework for the European Higher Education Area, is maintained through a national system of legal regulation and quality assurance, in the form of accreditation. The Ministry of Education, Culture and Science is responsible for legislation pertaining to education and the agriculture and public health ministries play an important role in monitoring the content of study programmes in their respective fields. Quality assurance is carried out through a system of accreditation, administered by the Accreditation Organisation of the Netherlands and Flanders (NVAO). According to the Dutch Higher Education Act, all degree programmes offered by research universities and universities of applied sciences must be evaluated according to established criteria. Programmes that meet those criteria are accredited: i.e. recognized for a period of six years. Only accredited programmes are eligible for government funding; students receive financial aid and graduate with a recognized degree only when enrolled in, and after having completed, an accredited degree programme. All accredited programmes are listed in the Central Register of Higher Education Study Programmes (CROHO). Besides the accreditation of degree programmes, the Netherlands has a system by which the Ministry of Education, Culture and Science recognizes higher education institutions by conferring on them the status of either "funded" or "approved". "Funded" indicates that the institution is fully financed by the government. "Approved" indicates that the institution does not receive funds from the government and has to rely on its own sources of funding. Whether a degree programme is offered by a "funded" or an "approved" institution, it must be accredited and registered in CROHO to be considered recognized. N.B. If a bachelor or master degree programme is not registered in the CROHO, the quality is not assured by the Dutch quality assurance system. The quality may however be assured by another system. National Qualifications Framework An important outcome of the Bologna process is the development of a "Framework for Qualifications of The European Higher Education Area". This overarching framework provides a general and common structure for qualifications awarded in countries signatory to the Bologna Declaration, and offers recommendations and guidelines for the development of mutually understandable qualifications frameworks at national levels. By the year 2010, all countries in the European Higher Education Area should have a national qualifications framework in place that complies with the goals and criteria of the European framework while describing the specific elements of each individual system. The Netherlands is one of the first countries in the European Higher Education Area to complete the national qualifications framework, which has subsequently been evaluated by the Verification Committee and found to be compatible with the overarching European Qualifications Framework. The National Qualifications Framework of the Netherlands describes in detail the various levels and learning outcomes associated with higher education qualifications, in terms that are internationally compatible. page 8 of 9

The responsibility for overseeing the framework and updating it when necessary has been allocated to the NVAO. Further information on the framework can be obtained on the NVAO website: www.nvao.net/nqf-nl. page 9 of 9