HUMAN GENETICS PRACTICE WORKSHEET #3. 1. Explain the difference between incomplete and codominance.

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Name Period: HUMAN GENETICS PRACTICE WORKSHEET #3 1. Explain the difference between incomplete and codominance. Co-Dominance Problems 2. In some chickens, the gene for feather color is controlled by codominance. The allele for black is B and the allele for white is W. The heterozygous phenotype is known as erminette (black and white spotted). a. What is the genotype for black chickens? b. What is the genotype for white chickens? c. What is the genotype for erminette chickens? 3. If two erminette chickens were crossed, what is the probability that: a. They would have a black chick? % b. They would have a white chick? % Parents: X 4. A black chicken and a white chicken are crossed. What is the probability that they will have erminette chicks? % Parents: X 5. What offspring are expected from mating a roan bull and a roan cow? 6. What phenotypes would you expect from a cross between a red bull and a white cow? 7. Two short-tailed (Manx) cats are bred together. They produce three kittens with long tails, five short tails, and two without any tails. From these results, how do you think tail length in these cats are inherited? Show the genotypes for both the parents and the offspring to support your answer.!1

Incomplete Dominance Problems 8. In snapdragons, flower color is controlled by incomplete dominance. The two alleles are red (R) and white (R ). The heterozygous genotype is expressed as pink. a. What is the phenotype of a plant with the genotype RR? b. What is the phenotype of a plant with the genotype R R? c. What is the phenotype of a plant with the genotype RR? 9. A pink-flowered plant is crossed with a white-flowered plant. What is the probability of producing a pink-flowered plant? % Parents: X 10. What cross will produce the most pink-flowered plants? Show a punnett square to support your answer. Parents: X 11. In Andalusian fowls, black individuals (BB) and white individuals (B B ) are homozygous. A homozygous black bird is crossed with a homozygous white bird. The offspring are all bluishgray. Show the cross as well as the genotypes and phenotypes of the parents and offspring. 12. What results if a black individual is crossed with a bluish-gray individual? (SHOW YOUR WORK) 13. If two bluish-gray individuals were crossed, what would be the ratios for both phenotype and genotype of the offspring?!2

Codominance (Blood types) Human blood types are determined by genes that follow the CODOMINANCE pattern of inheritance. There are two dominant alleles (I A and I B ) and one recessive allele (i). Blood Type (Phenotype) Genotype Can donate blood to: Can receive blood from: O ii A,B,AB and O (universal donor) O AB I A I B AB A,B,AB and O (universal receiver) A I A I A or I A i AB, A O,A B I B I B or I B i AB,B O,B 1. Write the genotype for each person based on the description: a. Homozygous for the B allele b. Heterozygous for the A allele c. Type O d. Type A and had a type O parent e. Type AB f. Blood can be donated to anybody g. Can only get blood from a type O donor 2. Pretend that Brad Pitt is homozygous for the type B allele, and Angelina Jolie is type O. What are all the possible blood types of their baby? (show your work) 3. Draw a Punnett square showing all the possible blood types for the offspring produced by a type O mother and an a Type AB father 4. Mrs. Clink is type A and Mr. Clink is type O. They have three children named Matthew, Mark, and Luke. Mark is type O, Matthew is type A, and Luke is type AB. Based on this information: a. Mr. Clink must have the genotype b. Mrs. Clink must have the genotype because has blood type c. Luke cannot be the child of these parents because neither parent has the allele.!3

5. Two parents think their baby was switched at the hospital. Its 1968, so DNA fingerprinting technology does not exist yet. The mother has blood type O, the father has blood type AB, and the baby has blood type B. a. Mother s genotype: b. Father s genotype: c. Baby s genotype: or d. Punnett square showing all possible genotypes for children produced by this couple e. Was the baby switched? 6. Two other parents think their baby was switched at the hospital. The mother has blood type A, the father has blood type B, and the baby has blood type AB. a. Mother s genotype: or b. Father s genotype: or c. Baby s genotype: d. Punnett square that shows the baby s genotype as a possibility: e. Was the baby switched? 7. Based on the information in this table, which man could not be the father of the baby? Justify your answer with a Punnett square. Name Mother Baby Sammy the player George the sleeze The waiter The cable guy Blood Type Type A Type B Type O Type AB Type A Type B 8. Based on the information in this table, which man could not be the father of the baby? Justify your answer with a Punnett square. Name Mother Baby Bartender Guy at the club Cabdriver Flight attendant Blood Type Type O Type AB Type O Type AB Type A Type B 9. Explain why blood type data cannot prove who the father of a baby is, and can only prove who the father is not.!4

X-linked Traits In fruit flies, eye color is a sex linked trait. Red (X R ) is dominant to white (X r ). 1. What are the sexes and eye colors of flies with the following genotypes: a. X R X r b. X R Y c. X R X R d. X r Y 2. What are the genotypes of these flies: a. white eyed, male b. red eyed female (heterozygous) c. white eyed, female d. red eyed, male 3. Show the cross of a white eyed female X r X r with a red-eyed male X R Y. 4. Show a cross between a pure red eyed female and a white eyed male. a. What are the genotypes of the parents & b. How many are white eyed, male c. How many are white eyed, female d. How many are red eyed, male e. How many are red eyed, female 5. Show the cross of a red eyed female (heterozygous) and a red eyed male. a. What are the genotypes of the parents? & b. How many are white eyed, male c. How many are white eyed, female d. How many are red eyed, male e. How many are red eyed, female!5

!6

6. In humans, hemophilia is a sex linked trait. Females can be normal, carriers, or have the disease. Males will either have the disease or not (but they won t ever be carriers)! = female, normal! = male, normal! = female, carrier! = male, hemophiliac! = female, hemophiliac a. Show the cross of a man who has hemophilia with a woman who is a carrier. b. What is the probability that their children will have the disease? 7. A woman who is a carrier marries a normal man. Show the cross. a. What is the probability that their children will have hemophilia? b. What sex will a child in the family with hemophilia be? 8. A woman who has hemophilia marries a normal man. a. How many of their children will have hemophilia, and what is their sex? In cats, the gene for calico (multicolored) cats is codominant. Females that receive a B and an R gene have black and orange splotches on white coats. Males can only be black or orange, but never calico. Here s what a calico female s genotype would look like. X B X R 9. Show the cross of a female calico cat with a black male. a. What percentage of the kittens will be black and male? b. What percentage of the kittens will be calico and male? c. What percentage of the kittens will be calico and female? 10. Show the cross of a female black cat, with a male orange cat.!7

a. What percentage of the kittens will be calico and female? b. What color will all the male cats be?!8