* Body movement is controlled by nerve impulses. Explain how impulses are transmitted in a reflex arc to prevent a person from injuring themselves.

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s Q1. * Body movement is controlled by nerve impulses. Explain how impulses are transmitted in a reflex arc to prevent a person from injuring themselves. (6)

Q2. In 1790, Italian biologist Luigi Galvani experimented on dead frogs. He demonstrated that the frogs legs moved when electricity was passed through them. (i) Complete the sentence by putting a cross ( ) in the box next to your answer. The electrical impulses that made the frog s leg move passed through the A circulatory system B digestive system C endocrine system D nervous system (ii) Explain how passing electricity through the frog s leg caused it to move. (iii) Explain how the structure of a sensory neurone maximises the speed of the impulse passing along it. Q3. Explain how information travels along the axon of a sensory neurone.

Q4. (a) (i) Complete the sentence by putting a cross ( A person with diabetes cannot control A the water content of their blood B the glucose content of their blood C their body temperature D their body mass index (ii) Explain how Type 1 diabetes can be controlled. ) in the box next to your answer. (b) Adrian is 180 cm tall and has a mass of 120 kg. A person who has a high Body Mass Index (BMI) is more likely to develop Type 2 diabetes. Calculate Adrian's BMI using the equation. (3) *(c) Body movement is controlled by nerve impulses. Explain how impulses are transmitted in a reflex arc to prevent a person from injuring themselves. (6) (Total for is 12 marks)

Q5. The diagram shows a motor neurone. (i) Name the structures labelled A, B and C. (3) A................................................................................................. B................................................................................................. C................................................................................................. (ii) When the brain receives impulses from receptor cells it coordinates a response. Complete the sentence by putting a cross ( Responses are carried out by A alleles B dendrons C effectors D senses ) in the box next to your answer.

Q6. The diagram shows a motor neurone. (a) (i) Name the structures labelled A, B and C. (3) A................................................................................................. B................................................................................................. C................................................................................................. (ii) When the brain receives impulses from receptor cells it coordinates a response. Complete the sentence by putting a cross ( Responses are carried out by A alleles B dendrons C effectors D senses ) in the box next to your answer.

(b) A response can be affected by drugs. The effect of drinking alcohol on reaction time was investigated using five adult volunteers A, B, C, D and E. After drinking a number of units of alcohol, the reaction time for each volunteer was measured three times. The results are shown in the table. %%% %%% Volunteer of units of alcohol 1 st attempt 2 nd attempt 3 rd attempt Mean drunk A 0.5 34 38 27 33 B 1.5 36 47 40 41 C 3.0 59 62 59 60 D 4.5 67 60 62 E 6.0 80 68 83 77 (i) Calculate the mean reaction time for volunteer D. Reaction time / ms (ii) Explain why alcohol causes a change in reaction time. (Total for is 8 marks)

Q7. Describe the pathway of a nerve impulse through a reflex arc. (3)

Q8. Responses (a) In 1790, Italian biologist Luigi Galvani experimented on dead frogs. He demonstrated that the frogs legs moved when electricity was passed through them. (i) Complete the sentence by putting a cross ( ) in the box next to your answer. The electrical impulses that made the frog s leg move passed through the A circulatory system B digestive system C endocrine system D nervous system (ii) Explain how passing electricity through the frog s leg caused it to move. (iii) Explain how the structure of a sensory neurone maximises the speed of the impulse passing along it.

(b) The diagram shows a gap between two neurones. (i) Give the name for the gap between two neurones. (ii) Describe how an impulse can continue to travel along a nerve pathway when there is a gap between two neurones. (4)

Q9. Describe the role of the myelin sheath. Q10. (i) Which of these drugs is a stimulant? Put a cross ( A alcohol B caffeine C LSD ) in the box next to your answer. D morphine (ii) Explain how stimulants affect reaction times.

Q11. The nervous system The diagrams show the structure of two neurones A and B. (a) Complete the sentences by putting a cross ( (i) Neurone A is a A motor neurone B reflex neurone C relay neurone D sensory neurone (ii) Neurone B sends information to the A brain and spinal cord B hormones which results in a response C muscle tissue D receptor cells in the skin ) in the box next to your answer. (b) Explain how information travels along the axon of a sensory neurone. (c) Describe the role of the myelin sheath. (d) Describe the pathway of a nerve impulse through a reflex arc. (3)

Q12. The diagram shows a gap between two neurones. (i) Give the name for the gap between two neurones. (ii) Describe how an impulse can continue to travel along a nerve pathway when there is a gap between two neurones. (4) Q13. Receptor cells in the skin detect temperature changes in the external environment. Explain how this information is transmitted to the brain. (4)

Mark Scheme Q1. Indicative Content Mark * An explanation including the following points in a logical order: a reflex response is an involuntary response reflex responses do not involve the brain reflex responses involve sensory neurones reflex responses involve relay neurones reflex responses involve motor neurones relay neurones are in the spinal cord impulses travel along neurones as electrical signals (6) the axon is insulated by the myelin sheath which ensures the electrical signal does not lose energy at the junction between two neurones there is a synapse the message is carried across the synapse by neurotransmitters the message travels from the stimulus along the axon and dendron of the sensory neurone to the spinal cord the reflex arc is important to keep the body safe Level 0 No rewardable content 1 1-2 A limited written explanation of some of the neurones involved in the reflex arc or a limited explanation of how messages /impulses are transmitted as electrical

2 3-4 3 5-6 signals the answer communicates ideas using simple language and uses limited scientific terminology spelling, punctuation and grammar are used with limited accuracy A simple explanation of the neurones involved in the reflex arc in the correct order, with the method of transmission along neurones, one neurone may be missing or a detailed description of all of the neurones in the reflex arc and the role of the CNS the answer communicates ideas showing some evidence of clarity and organisation and mostly uses scientific terminology appropriately spelling, punctuation and grammar are used with some accuracy A detailed explanation of the neurones involved in the reflex arc in the correct order, with the method of transmission along neurones including the role of the synapse and/or myelin sheath. the answer communicates ideas clearly and coherently uses a range of scientific terminology accurately spelling, punctuation and grammar are used with few errors Q2. (i) D (ii) An explanation linking the following points in a logical order electrical impulses passed along motor neurone causing the muscles to contract (iii) An explanation linking the following points in a logical order the myelin sheath

insulates the sensory neurone which reduces loss of signal an explanation linking the following from receptor (cells) / sense organ to the brain / spinal cord / CNS / synapse / other neurone as an electrical impulse Accept named sense organ electrical message/signal Ignore references to current a (i) a (ii) b Answer B the glucose content of their blood An explanation linking three of the following points: (the hormone) insulin (insulin )is injected (into subcutaneous fat) use a low carbohydrate /healthy diet (increase) exercise to lower blood glucose levels / when blood glucose levels get too high / regulate glucose levels Body Mass Index calculation: 120 1.8 2 37 Acceptable answers use of epipen ecf for correct manipulation with incorrect figures Mark (3) QWC *(c) Indicative Content An explanation including the following points in a logical order: a reflex response is an involuntary response Mark (6)

reflex responses do not involve the brain reflex responses involve sensory neurones reflex responses involve relay neurones reflex responses involve motor neurones relay neurones are in the spinal cord impulses travel along neurones as electrical signals the axon is insulated by the myelin sheath which ensures the electrical signal does not lose energy at the junction between two neurones there is a synapse the message is carried across the synapse by neurotransmitters the message travels from the stimulus along the axon and dendron of the sensory neurone to the spinal cord the reflex arc is important to keep the body safe Level 0 No rewardable content 1 1-2 A limited written explanation of some of the neurones involved in the reflex arc or a limited explanation of how messages /impulses are transmitted as electrical signals the answer communicates ideas using simple language and uses limited scientific terminology spelling, punctuation and grammar are used with limited accuracy 2 3-4 A simple explanation of the neurones involved in the reflex arc in the correct order, with the method of transmission along neurones, one neurone may be missing or a detailed description of all of the neurones in

3 5-6 the reflex arc and the role of the CNS the answer communicates ideas showing some evidence of clarity and organisation and mostly uses scientific terminology appropriately spelling, punctuation and grammar are used with some accuracy A detailed explanation of the neurones involved in the reflex arc in the correct order, with the method of transmission along neurones including the role of the synapse and/or myelin sheath. the answer communicates ideas clearly and coherently uses a range of scientific terminology accurately spelling, punctuation and grammar are used with few errors Answer Acceptable answers Mark (i) A nucleus B myelin (sheath) A cell body B Schwann cell / fatty C axon layer (3) (ii) C - effectors Answer Acceptable answers Mark a(i) A nucleus B myelin (sheath) A cell body B Schwann cell / fatty C axon layer (3) a(ii) C - effectors b(i) (67 + 60+ 62) = 189 (189) / 3 ans = 63 (ms) Two marks for correct bald answer ECF for incorrect calculation carried b(ii) An explanation to include the following points: alcohol is a depressant slows down the activity of the brain (slows down) neurotransmission (slows down) transmission at the synapse out correctly. Reject stimulant (no further marks awarded) Ignore references to CNS accept sedative accept: slows reactions / reactions take longer / reaction time increases Total for question = 8 marks

a description including three of the following receptor cells (pick up a stimulus) sensory neurone sends a message to the spinal cord / relay neurone / CNS the message travels from the relay neurone / CNS / spinal cord to the motor neurone (this initiates a response) in the effector / muscle / gland message travels across synapse (by neurotransmitters) accept the correct nerve pathway diagram for 3 marks accept nerve for neurone (3) (a)(i) D (a)(ii) An explanation linking the following points in a logical order electrical impulses passed along motor neurone causing the muscles to contract (a)(iii) An explanation linking the following points in a logical order the myelin sheath insulates the sensory neurone which reduces loss of signal

(b)(i) synapse (b)(ii) A description including the following points in a logical order the electrical impulse stimulates the release of a neurotransmitter at the synapse the neurotransmitter diffuses across the synapse (as a chemical messenger) which fits into the receiving neurone this stimulates an electrical impulse in the receiving neurone Accept chemical messenger for neurotransmitter Accept chemical messenger across the gap between neurones (4) a description including two of the following insulates (electrical signal) the axon speeds up the impulse ignore protects / protection accept message / signal for impulse Answer Acceptable answers Mark (i) B caffeine (ii) An explanation linking the following points stimulants reduce reaction times/increase the speed of reactions / speed up reaction times by increasing neurotransmission speed up neurotransmission

acts at the synapse (a)(i) A (a)(ii) A (b) (c) (d) an explanation linking the following from receptor (cells) / sense organ to the brain / spinal cord / CNS / synapse / other neurone as an electrical impulse Accept named sense organ electrical message/signal Ignore references to current a description including two of the following insulates (electrical signal) the axon speeds up the impulse ignore protects / protection accept message / signal for impulse a description including three of the following receptor cells (pick up a stimulus) sensory neurone sends a message to the spinal cord / relay neurone / CNS the message travels from the relay neurone / CNS / spinal cord to the motor neurone (this initiates a response) in the effector / muscle / gland message travels across synapse (by neurotransmitters) accept the correct nerve pathway diagram for 3 marks accept nerve for neurone (3)

(i) synapse (ii) A description including the following points in a logical order the electrical impulse stimulates the release of a neurotransmitter at the synapse the neurotransmitter diffuses across the synapse (as a chemical messenger) which fits into the receiving neurone this stimulates an electrical impulse in the receiving neurone Accept chemical messenger for neurotransmitter Accept chemical messenger across the gap between neurones (4) Answer An explanation linking the following points (travel along) sensory neurones axons / dendrons as electrical / electric impulses across synapses (gap between two neurones) using neurotransmitters reference to spinal cord /CNS reference to myelin sheath Acceptable answers dendrites accept signals for impulses ignore electronic Mark (4)