12/20/2011. Risk Assessment Using Uncertainty in Decision Making. best part of knowledge. Lao Tzu The Tao. Module

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Module 11: Monte Carlo Risk Assessment 11.3 Using Uncertainty in Decision Making To know one s ignorance is the best part of knowledge Lao Tzu The Tao Module 11.3 2 1

Outline Understanding Uncertainty Probabilistic Assessment Using Uncertainty Introduction to Decision Analysis Example of Understanding and Using Uncertainty in Risk Based Decision Making under CERCLA Conclusions Module 11.3 3 Understanding Uncertainty Traditional calculations and models use single value estimates for input variables and result in a single value risk models engineering calculations If conservatism is needed, a variety of methods are used to provide it use worst case estimates rather than best guess apply a safety factor to the final calculations Module 11.3 4 2

Understanding Uncertainty This approach provides little information on the range of values that may exist and their relative probabilities The degree of conservatism is unknown and controversial Usually involves an ad hoc discussion of uncertainty Doesn t distinguish between variability and uncertainty Module 11.3 5 Understanding Uncertainty It s important to distinguish between variability and uncertainty Variability refers to the differences that come from heterogeneity or diversity in a population. Variability is usually not reducible by further study. Uncertainty refers to the lack of knowledge about specific factors, parameters, or models. Uncertainty can potentially be reduced by additional study. Module 11.3 6 3

Understanding Uncertainty Probabilistic Assessment replaces single point estimates with probability distributions Distributions reflect variability and/or uncertainty Distributions are created from: Data Information from the scientific literature Expert Judgement, experience Module 11.3 7 Understanding Uncertainty Either mathematical techniques (calculus) or empirical techniques (Monte Carlo Analysis) are used to propagate the uncertainty through the risk model In this way, a distribution on the model output variable is created Module 11.3 8 4

Understanding Uncertainty Monte Carlo Analysis Monte Carlo methods involve a random selection of values from each input probability distribution These values are then used in the model to get an output value This procedure is repeated a large number of times (N=100, 500, 1000, 10000) Together, the output values define a probability distribution on the model output Module 11.3 9 Understanding Uncertainty Model Inputs Equation or Model Model Output Module 11.3 10 5

@RISK Functions Module 11.3 11 Simulation Settings - Iterations Module 11.3 12 6

Inputs by Outputs Table Module 11.3 13 Histogram and CDF of Output Distribution Module 11.3 14 7

If we begin with certainties, we shall end in doubts; but if we begin with doubts, and are patient in them, we shall end in certainties Francis Bacon Module 11.3 15 Using Uncertainty in Scientific Decision Making Once the assessment is complete, a single value from the distribution could be used 95th percentile 99th percentile But this ignores most of the information contained in the distribution. And distributions with differing shapes have the same upper percentile. Could there be important characteristic of the distribution (shape, central tendency) which should be taken into account? Module 11.3 16 8

Using Uncertainty in Scientific Decision Making Two types of decision errors can occur in risk management decision making Type I False Positive Conclude that remediation is warranted at a site when it isn t Do more remediation than is necessary to meet management goals Module 11.3 17 Using Uncertainty in Scientific Decision Making Type II False Negative Conclude that remediation is not warranted at a site when it is Do too little remediation to meet risk management goals A loss function makes the losses for each of these types of decision errors explicit Module 11.3 18 9

Using Uncertainty in Scientific Decision Making Once the set or space of alternative decisions is defined and the loss function is determined Decision analysis provides a framework for calculating the expected loss for each alternative decision (using the probability distribution from the PA) The best decision is the one that minimizes the expected loss This determination can be used (along with all other information) to help determine the best course of action Module 11.3 19 Using Uncertainty in Scientific Decision Making Note: Loss functions can be difficult to define and get agreement on There may be multiple decision makers and they may have different loss functions It is difficult and sometimes impossible to turn values into numerical quantities Module 11.3 20 10

Using Uncertainty in Scientific Decision Making However, there may be value in having the discussion Exposes areas of agreement and disagreement Educates everyone about the other s point of view Increases transparency of decision making Can repeat the analysis with different loss functions Module 11.3 21 The man who insists upon seeing with perfect clearness before he decides, never decides. Frederic Amiel Module 11.3 22 11

Example of Understanding and Using Uncertainty in Risk Based Decision Making under CERCLA Exposure analysis involving a food web model of uptake of PCBs into flounder in New Bedford Harbor Eleven model input variables had significant uncertainty Sensitivity analysis showed that six of the eleven were important in controlling output uncertainty Using literature values and expert judgement, uncertainty distributions were created for the six variables Module 11.3 23 Example of Understanding and Using Uncertainty in Risk Based Decision Making under CERCLA Module 11.3 24 12

Example of Understanding and Using Uncertainty in Risk Based Decision Making under CERCLA Probability 0.15 0.1 005 0.05 Total PCB Body Burden for Flounder 0 4 6 8 10 12 14 16 18 20 22 Flounder Body Burden (micrograms per gram) Management Question: How many cubic meters of sediment in inner New Bedford Harbor must be dredged to meet a management criteria of 2 micrograms of PCB per gram of flounder? Module 11.3 25 Example of Understanding and Using Uncertainty in Risk Based Decision Making under CERCLA The model and some assumptions were used to relate a reduction in PCB concentration in the sediment to a reduction in flounder body burden A loss function was created that estimated the losses associated with under-remediation and with overremediation assuming $1,000 per cubic meter dredged and incinerated $50 million penalty for under-remediation remediation resulting from a need to keep the fishery closed for five additional years while undergoing re-remediation Module 11.3 26 13

Example of Understanding and Using Uncertainty in Risk Based Decision Making under CERCLA Loss Function: L(A B i ) = $1,000 A for A >= B i $1,000 B i + $50 million for A < B i where A is the area to be dredged (m 3 ) under a particular decision scenario, B i is the correct (but unknown) area necessary to dredge to just meet the management criterion if the i th replication of the Monte Carlo was true, and L(A B i ) is the loss associated with making a less than optimal decision Module 11.3 27 Example of Understanding and Using Uncertainty in Risk Based Decision Making under CERCLA Expected Loss: where E[L(A)] is the expected loss for decision A and N is the number of replications from the Monte Carlo E [ L ( A )] 1 N N i 1 L ( A Bi ) Module 11.3 28 14

Example of Understanding and Using Uncertainty in Risk Based Decision Making under CERCLA Decision: Calculate the expected loss for different management decisions and select the one that minimizes the expected loss Module 11.3 29 Conclusions Monte Carlo techniques allow the uncertainty in a scientific decision i making situation ti to be determined d by propagating the uncertainties in the inputs through the equation or model to get a probability distribution on the output Decision analysis can be useful in scientific decision making, especially where significant uncertainties exist, because it makes explicit the losses associated with different actions and helps the decision maker select an alternative that minimizes the expected loss Module 11.3 30 15

we demand rigidly defined areas of doubt and uncertainty The Hitchhiker s Guide to the Galaxy Module 11.3 31 16