Male genitalia Pathology MCQs 1.The epididymis is distended, swollen and contains thick purulent material. The most likely cause is: A. mumps B. tuberculosis C. gonorrhea D. seminoma E. spermatocele 2.A 68-year-old man has frequent urination and difficulty starting the urinary stream. The most likely cause of his symptoms is: A. hyperplasia of the prostate B. diabetes mellitus C. cystitis D. carcinoma of the prostate E. carcinoma of the bladder 3.Distant metastasis in prostatic carcinoma most commonly involves: A. lung B. brain C. bone D. liver E. adrenal 4.Prostatic carcinoma: A. usually arises in the anterior lobe B. often can be detected by palpitation before the patient has any symptoms of the lesion C. both D. neither
5.Which of the following is the best way to determine if the removal of a choriocarcinoma of the testes has been successful? A. examination of the regional lymph nodes B. assay of gonadotropin levels C. palpation of the contents of the scrotum D. careful palpation of the liver E. measurement of alkaline phosphatase levels 6.Which testicular tumor is most likely to contain a variety of tissue patterns? A. seminoma B. interstitial cell tumor C. embryonal carcinoma D. teratocarcinoma E. choriocarcinoma 7.Production of gonadotropins is most characteristic of: A. adenocarcinoma of the prostate B. seminoma of the testis C. embryonal carcinoma of the testis D. choriocarcinoma of the testis E. teratoma of the testis 8.Features of testicular germ cell neoplasms include: A. most common after age 60 B. low potential for metastasis C. usually present with pain and hematuria D. often have a mixture of histologic patterns 9.Which is characteristic of testicular choriocarcinoma? A. 20% of testicular tumors B. low grade malignancy C. reproduces epithelial components of yolk sac
D. high levels of chorionic gonadotropin E. good 5-year survival rate 10.A testicular neoplasm composed of round or polyhedral cells with prominent nucleoli and reactive lymphatic infiltrate in a loose stroma is: A. Leydig tumor B. teratoma C. choriocarcinoma D. seminoma E. embryonal carcinoma 11.Which is not a germ cell tumor? A. seminoma B. interstitial cell tumor C. embryonal carcinoma D. teratocarcinoma E. choriocarcinoma 12.Painless enlargement of the testis without involvement of the epididymis is most characteristic of: A. torsion of the testis B. germ cell tumor C. hydrocele D. spermatocele E. orchitis 13.Increased incidence of malignant testicular germ cell tumors correlates with: A. old age B. a history of orchitis C. undescended testis D. a history of trauma to the testis E. the presence of adrenal hyperplasia
14.The most frequent cause of urinary obstruction in the male is: A. benign prostatic hypertrophy B. carcinoma of prostate C. staghorn calculus D. hydronephrosis E. pyelonephritis 15.The blood test most useful in the diagnosis of metastatic carcinoma of the prostate is the serum: A. alpha-fetoprotein B. acid phosphatase C. prostatic mucin D. amylase E. alkaline phosphatase 16.Adenocarcinoma of the prostate characteristically: A. arises in the anterior lobe of the prostate B. causes sudden urinary retention C. causes a rise in alpha-fetoprotein D. is composed of glands smaller in size than normal prostate glands 17.The most common pure germ cell tumor of the testis is: A. embryonal carcinoma B. choriocarcinoma C. seminoma D. teratocarcinomna E. interstitial cell tumor 18.A 20-year-old male has painless enlargement of the right testis, noted on routine physical exam. Serum levels of chorionic gonadotrophin, alpha fetoprotein, alkaline phosphatase, and carcinoembryonic antigen are not elevated. At surgery a neoplasm of the testis is found. The neoplasm is most likely to be: A. embryonal carcinoma
B. seminoma C. interstitial cell tumor D. choriocarcinoma 19.The blood test most useful in the diagnosis of metastatic carcinoma of the prostate is the serum: A. alkaline phosphatase B. glutamic-oxaloacetic transaminase C. acid phosphatase D. lipase E. amylase 20.Which of the following is/are more characteristic of hyperplasia of the prostate than of carcinoma of the prostate? A. location in posterior lobe B. symptoms of urethral obstruction C. both D. neither 21.A cystic translucent mass above the testicle is probably a: A. spermatocele B. varicocele C. hydrocele D. hematocele 22.A sudden onset of testicular pain in a 25-year-old male suggests: A. seminoma B. Klinefelter s syndrome C. torsion D. infected varicocele E. cryptorchidism
23.A 70-year-old male has a 1 cm hard posterior lump palpable on rectal exam. His prostate is otherwise normal in size and consistency. His serum prostatic acid phosphatase is not elevated. Our working diagnosis is: A. adenocarcinoma of the prostate gland B. nodular hyperplasia of the prostate gland C. chronic prostatitis D. acute prostatitis 24.A 70-year-old male has a 1 cm hard posterior prostatic lump palpable on rectal exam. His prostate is otherwise normal in size and consistency. His serum prostatic acid phosphatase is not elevated. The lesion is biopsied. Small irregular glands lined by a single layer of cells with large nucleoli are observed. The stroma has focal collections of lymphocytes. We are dealing with the process of: A. neoplasia B. hyperplasia C. glanulomatous inflammation D. acute inflammation E. coagulation necrosis 25.The most frequent cause of urinary obstruction in the male is: A. benign prostatic hypertrophy B. carcinoma of prostate C. transitional cell carcinoma of bladder D. cryptorchism E. torsion of the testes 26.A one (1) cm painless firm nodule in the testis of a 25-year-old man is most likely: A. Leydig cell tumor B. germ cell tumor C. varicocele D. epididymal abscess E. mumps orchitis
27.Benign prostatic hypertrophy is not associated with: A. residual urine B. bladder trabeculation C. cystocele D. cystitis E. dysuria 28.A 70-year-old male has a 1 cm hard posterior prostatic lump palpable on rectal exam. His prostate is otherwise normal in size and consistency. His serum prostatic acid phosphatase is not elevated. The serum prostatic acid phosphatase is not elevated because: A. there is no or minimal extension outside the prostatic capsule B. there is no urinary obstruction C. skin test for tuberculosis is positive D. there is pus in his urine 29.An elevated serum alkaline phosphatase is most suggestive of: A. papillary carcinoma of bladder B. renal tubular adenocarcinoma C. benign prostatic hypertrophy D. seminoma E. metastatic adenocarcinoma of prostate 30.The most important factor to consider in the prognosis of malignant soft tissue tumors is: A. staging of the lesion B. histologic grading C. nuclear pleomorphism D. N/C ratio
31.A retroperitoneal mass is found in a young man. A biopsy of the mass shows large pleomorphic cells with abundant cytoplasm arranged in a storiform pattern. The most likely diagnosis is: A. chondrosarcoma B. malignant fibrous histiocytoma C. cystadenocarcinoma D. Krukenberg tumor E. seminoma **AS4**