Wearable Brain Sensing Devices

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Wearable Brain Sensing Devices 1, Brian Murphy 2, Cassandra Cortez 1 Carnegie Mellon University 1 Queen s University of Belfest 2 Oct 28, 2014 1

Outline 1. A survey of wearable brain sensing devices that are available on the market 2. Using wearable brain sensing devices to measure cognitive health in seniors and help address medication non adherence 2

Electroencephalography (EEG) EEG uses electrodes on the surface of the scalp to measure the voltage signal arising from large areas of coordinated neural activity. Electrophysiological biosignals are already used in the diagnosis and prognosis of a wide range of neurological conditions that afflict older people (e.g., Alzheimer's disease and other forms of dementia, ) 3

Wearable Brain Sensing Devices 4

NeuroSky EEG chip manufacture that offers a EEG biosensor platform, early mover since 2007 Single dry electrode (FP1), a variety of form factors, $99~$149 Focused on consumer market (e.g. partner with Mattel MindFlex, Uncle Milton Star Wars Force Trainer, Puzzlebox Orbit) http://neurosky.com/ 5

Emotiv Emotiv EPOC (2009) 14 dry electrodes (AF3, F7, F3, FC5, T7, P7, O1, O2, P8, T8, FC6, F4, F8, AF4), accelerometer, $399 Emotiv Insight (2015) 5 hydrophilic polymer sensors (AF3, AF4, T7, T8, Pz) + 9-axis inertial sensors, $299 Focused on research market (e.g. parter with Tobii, the eye tracking company) http://emotiv.com/ 6

New Players InteraXon Muse (2014): 4 (FP1, FP2, TP9, TP10) dry electrodes, accelerometer, $299 Recent strong entrant, Indiegogo success followed by $7m funding round http://www.choosemuse.com Electroencephalography (EEG) ifocusband (2014) 2 (FP1, FP2) soft woven dry sensors, rugged, low key, $310 Focused on the sport training markets (e.g., prototype used by 8 US PGA Tour professionals) http://www.ifocusband.com/ 7

Measure Cognitive Wellness in Seniors Aging patients are monitored infrequently in the clinic, due to costs in time and money Presented condition may not be representative Progress of degeneration is hard to track Sudden deteriorations may be missed 8

A Use Case A 70 yr old man, healthy, but at risk Data mines Informs Updates time 9

Medication Adherence is an impending problem for healthcare outcomes Non-adherence to medication costs the US healthcare system USD 100 289 Billion per year 2X Age > 65 yrs old 10 By 2030, the Baby Boomer generation is projected to increase elderly population to 70 Million

Patient Treatment Journey & Pain Points Experience Symptoms Consult with Physician Obtain Medication Adherence Monitor effectiveness Address adverse effects or crossreactivity Resolving Treatment Issues Positive reinforcement 11

Competitive Landscape Patient Brochure Pill Packaging Email Reminders Physician-Patient Monitoring Devices Mobile app 12

MVP: Medication Adherence Network Wearable Brain Sensing Device Monitor effectiveness Positive reinforcement Internet Cloud Channel Partners Payers Employers 13

Looking Forward Wearable systems, via smart-phones, tablet computers Early-warning systems e.g. for every 1,000 customers, in a single year could expect several incidences of stroke, >50 incidence s of Alzheimer s, ~200 individuals with depressive episodes Automated alerts to clinicians if danger of acute condition Patient-tailored 'gaming' tasks to halt cognitive decline Self-management of chronic illness e.g. anti-depressives 14

Point of Contact Kai-min Kevin Chang Language Technologies Institute, CMU E-mail: kkchang@cs.cmu.edu Phone: (412) 268-1810 Brian Murphy Queen s University Belfest E-mail: brian.murphy@qub.ac.uk Phone: +44 (0)28 9097 4652 Cassandra Cortez Tepper School of Business, CMU E-mail: ccortez@tepper.cmu.edu Phone: (323) 861-5567 15