Survey Shows that Many Asthma Sufferers Have Misconceptions about How to Control Their Condition

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Survey Shows that Many Asthma Sufferers Have Misconceptions about How to Control Their Condition Two Thirds of Physicians Treating Asthma Believe Less Than 50% of Their Patients Take Their Daily Asthma Controller Medication as Instructed Misconceptions about Asthma Control Are Particularly Prevalent among Hispanics and African Americans Public Release Date: July 14, 2009, 11:00 am EST Ipsos Public Affairs is a non-partisan, objective, survey-based research practice made up of seasoned professionals. We conduct strategic research initiatives for a diverse number of American and international organizations, based not only on public opinion research, but elite stakeholder, corporate, and media opinion research. Ipsos has media partnerships with the most prestigious news organizations around the world. Ipsos Public Affairs is the polling agency of record for The McClatchy Company, the third-largest newspaper company in the United States and the international polling agency of record for Thomson Reuters, the world s leading source of intelligent information for businesses and professionals. Ipsos Public Affairs is a member of the Ipsos Group, a leading global survey-based market research company. We provide boutique-style customer service and work closely with our clients, while also undertaking global research. To learn more, visit: www.ipsos-pa.com For copies of other news releases, please visit: www.ipsos-na.com/news/. 2009, Ipsos Public Affairs Page 1

Survey Shows that Many Asthma Sufferers Have Misconceptions about How to Control Their Condition Two Thirds of Physicians Treating Asthma Believe Less Than 50% of Their Patients Take Their Daily Asthma Controller Medication as Instructed Misconceptions about Asthma Control Are Particularly Prevalent among Hispanics and African Americans New York, NY An Ipsos poll conducted on behalf of Astra Zeneca and the Asthma and Allergy Foundation of America found that although an overwhelming majority of asthma sufferers (97%) agree that there are serious risks associated with uncontrolled asthma, many have misconceptions about asthma control. Most physicians treating asthma sufferers do not believe their patients take their medications appropriately, as over two thirds (68%) believe that less than 50% of their patients take their daily asthma controller medication as instructed. The study also found that two thirds of asthma sufferers (66%) believe that asthma is a very or extremely serious condition. Higher proportions say the same of diabetes (78%) or high blood pressure (73%), though fewer consider obesity (63%), high cholesterol (57%) or arthritis (43%) to be very or extremely serious. Hispanics (78%) and African Americans (84%) are particularly likely to believe asthma is a very or extremely serious condition. Despite the seriousness of the condition and the risks associated with not controlling it, many asthma sufferers still have mistaken beliefs on how to adequately treat their condition. Most sufferers (94%) say they know the difference between a quick-relief medication and a controller medication; however, two thirds (69%) agree quickrelief medications can be used every day, and four in ten (42%) agree that it is appropriate to take controllers less regularly when symptoms decrease. Majorities of Hispanic (60%) and African-American sufferers (52%) say it is appropriate to take controllers less regularly when asthma symptoms decrease. Furthermore, one quarter of all asthma sufferers (25%), say it is appropriate to stop taking a controller when they are no longer experiencing asthma symptoms. This opinion is also more prevalent among Hispanic (42%) and African-American sufferers (31%). 2009, Ipsos Public Affairs Page 2

Controller Medications Over six in ten asthma sufferers surveyed (62%) are currently taking a controller medication, most of whom (84%) say that they take their controller on a regular basis. However, over one in ten (12%) report taking their controller as needed for quick relief of an asthma attack. African-American (20%) and Hispanic (18%) sufferers are more likely than the general population of asthma sufferers to report they use controller medications for quick relief. In addition, among all sufferers close to three in ten (28%) report having stopped taking any controller medication. Among them, seven in ten (71%) report they are not currently taking a controller because they only do so when they have asthma symptoms, or because they consider their asthma to be currently under control without the controller medication (70%). One in three (34%) asthma sufferers who reportedly stopped using their controller because their health care professional said they no longer needed it. Similarly, many physicians agree that it is appropriate for severe to moderate asthma patients to take their controller medication less regularly when asthma symptoms decrease (22%), and to stop taking it if symptoms are no longer experienced (14%). Even so, most physicians have some concerns about their patients discontinuing use of their controller medications. Most would be concerned that their patients would have to go to the emergency room because of an asthma attack (79%); that they would present an underlying progression of their asthma (78%); or that they would have to be hospitalized due to an asthma attack (76%). Indeed, considerable proportions of sufferers who stopped taking their controller medication for any period of time in the past 12 months have experienced negative consequences: 21% required treatment with steroid pills; 17% had an emergency doctor visit including 32% of African Americans; 15% had serious health consequences; 12% had to miss work including 23% of Hispanics; 12% had to go to the emergency room including 26% of African Americans; and 6% were admitted to a hospital. These are some of the findings of an Ipsos poll conducted June 27 - August 18, 2008 on behalf of Astra Zeneca and the Asthma and Allergy Foundation of America. For the survey, a nationally representative sample of 1,001 asthma sufferers from all ethnicities and region were interviewed, in addition to: a supplementary sample of 436 African-American asthma sufferers across the United States to complement those from the national sample in order to achieve a total sample of 503; and an additional 448 Hispanic asthma sufferers across the United States to complement those from the national sample in order to achieve a total sample of 500 were interviewed. 2009, Ipsos Public Affairs Page 3

Asthma sufferers were interviewed by telephone and were randomly selected from two sample sources: Ipsos national consumer telephone access panel with more than 6,000 adult members who have reported being diagnosed as asthma sufferers; and targeted lists obtained from the Marketing System Group (MSG). In addition, a sample of 300 primary care physicians (PCPs) including general practitioners, family practitioners, and internal medicine practitioners were interviewed online. In order to qualify for the study, physicians must have treated at least three asthma patients per week on average, and be board-certified or board-eligible. Physicians were randomly selected from e- Rewards managed online panel of general practitioners, family practitioners, and internal medicine practitioners. With samples of this size, the results are considered accurate within ±3.1 percentage point for the national sample of sufferers; and ±4.4 percentage points for the African-American and Hispanic Samples; and ±5.7 percentage points for the physicians sample 19 times out of 20, of what they would have been had the entire population of adults suffering from asthma who have taken medication to control their asthma in the past 12 months in the U.S. been polled, or the entire population of board certified or eligible primary care physicians treating asthma patience the US been polled. The margin of error will be larger within regions and for other sub-groupings of the survey population. These data were weighted to ensure the sample's age/gender composition reflects that of the actual asthma sufferers in the U.S. according to data from the U.S. Census Bureau. ### For more information on this news release, please contact: Nicolas Boyon Senior Vice President Ipsos Public Affairs 646.364.7583 Or Julio Franco Research Manager Ipsos Public Affairs 646.313.6117 Releases are available at: http://www.ipsos-na.com/news/ 2009, Ipsos Public Affairs Page 4

About Ipsos Ipsos is a leading global survey-based market research company, owned and managed by research professionals that helps interpret, simulate, and anticipate the needs and responses of consumers, customers, and citizens around the world. Member companies assess market potential and interpret market trends to develop and test emergent or existing products or services, and build brands. They also test advertising and study audience responses to various media, and measure public opinion around the globe. They help clients create long-term relationships with their customers, stakeholders or other constituencies. Ipsos member companies offer expertise in advertising, customer loyalty, marketing, media, and public affairs research, as well as forecasting, modeling, and consulting and offers a full line of custom, syndicated, omnibus, panel, and online research products and services, guided by industry experts and bolstered by advanced analytics and methodologies. The company was founded in 1975 and has been publicly traded since 1999. In 2008, Ipsos generated global revenues of 979.3 million ($1.34 billion U.S.). Visit www.ipsos.com to learn more about Ipsos offerings and capabilities. 2009, Ipsos Public Affairs Page 5