Guiding Pharmacy Students To Adopt A Patient-Centered Practice: Exploring The Problem Of Medication Non-Adherence

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Guiding Pharmacy Students To Adopt A Patient-Centered Practice: Presented by: Vivian Lee BScPhm candidate UW School of Pharmacy Faculty supervisor: Certina Ho Adjunct Clinical Professor UW School of Pharmacy Exploring The Problem Of Medication Non-Adherence

Outline Background Pharmacy education Adherence to bisphosphonate therapy Research question Method and Deliverables Using the PASSAction framework Implications Discussion for the audience

Outline Background Pharmacy education Adherence to bisphosphonate therapy Research question Method and Deliverables Using the PASSAction framework Implications Discussion for the audience

Pharmacy Education

Pharmacy Education in Canada Science and therapeutics of drugs Pathophysiology (what is this disease? how does it present?) Therapeutics (how do you treat it? i.e., which drugs?) Pharmacology (how does the drug work at a molecular level?) Pharmacokinetics (how does the drug work at a kinetics level?) Medicinal chemistry (what is the chemical structure of the drug?)

Pharmacy Education at UW Application of knowledge in patient care Indication Effectiveness Safety Adherence

What is Adherence? The extent to which a person s behaviour, such as taking medications, following a diet and/or executing lifestyle changes, corresponds to agreed-upon recommendations from a health care provider

How UW pharmacy students assess adherence in paper cases Does the patient prefer not to take the drug? Does the patient understand the directions for use? Does the patient forget to the take the drug? Is the drug too expensive for the patient? Can the patient swallow/administer the drug? Is the drug available?

How UW pharmacy students assess adherence in paper cases Does the patient prefer not to take the drug? Does the patient understand the directions for use? Does the patient No forget issues to the take the drug? Is the drug too expensive for the patient? Can the patient swallow/administer the drug? Is the drug available?

Assessing adherence We should never assume Drugs don t work in patients who don t take them C. Everett Koop, M.D.

Adherence to Bisphosphonates Bisphosphonates chronic medications for treatment and prevention of osteoporosis Importance of adhering to bisphosphonates? Osteoporosis poses a significant burden to health and health care costs Adhering to medications is key to preventing osteoporosis and/or fragility fractures

Adherence to Bisphosphonates Bisphosphonate adherence is poor 20-30% discontinue the drug as early as within 6 months Patients need to take bisphosphonates consistently for at least 6 months to derive benefit from therapy

Research Question How can adherence to bisphosphonates be improved in community pharmacy practice?

Using the PASSAction Framework

The PASSAction Framework P Problem or patient encounter ACTION Put your strategy to action A Adherence factors SS Set your strategy

P Problem or Patient Encounter P Problem or patient encounter

P Problem or Patient Encounter P Patients are not adhering to bisphosphonates

A Adherence Factors P Problem or patient encounter A Adherence factors

Adherence Factors Complex administration instructions Lack of standardized medication information Asymptomatic nature of the disease Lack of belief in the purpose or benefits of taking the medication Lack of trusting and supportive patient-health care provider relationships

SS Set Your Strategy P Problem or patient encounter A Adherence factors SS Set your strategy

How can bisphosphonate adherence be improved? Strategies to improve adherence: Use a multifaceted approach Present educational information in multiple forms (audio, visual, tactile)

How can bisphosphonate adherence be improved? Complex administration procedures Patient education video Lack of standardized medication information Lack of belief in purpose of the medication Lack of trusting and supportive relationships with HCPs Medication information leaflet Pharmacist follow-up phone call

Intervention 1: Patient education video Describes purpose of the medication Demonstrates administration procedures Provides tips for establishing a medicationtaking system http://www.youtube.com/watch?v=jdurtx3uk jw

Intervention 2: Medication Information Leaflet Common uses How to use the medication Possible side effects

Intervention 3: Pharmacist follow-up phone call Reinforce the purpose and benefits of taking the medication Reinforce proper administration procedures Encourage patients to address any questions or concerns about osteoporosis and/or bisphosphonate therapy

How do we measure adherence? ADEOS Questionnaire: Adherence Evaluation of Osteoporosis Qualitative, patient-reported adherence 12 questions with answer choices Validated: Postmenopausal women with osteoporosis Taking bisphosphonate therapy

Action P Problem or patient encounter ACTION Put your strategy to action A Adherence factors SS Set your strategy

Study Design

Patient recruitment at selected pharmacy site Patients answer ADEOS (pre-intervention) 2-3 weeks Patients watch a 3-minute educational video clip and receive information leaflet Patient receives a followup phone call from the pharmacist 2-3 weeks Patients answer ADEOS (post-intervention)

Patient recruitment at selected pharmacy site Patients answer ADEOS (pre-intervention) 2-3 weeks Patients watch a 3-minute educational video clip and receive information leaflet Patient receives a followup phone call from the pharmacist 2-3 weeks Patients answer ADEOS (post-intervention)

Patient recruitment at selected pharmacy site Patients answer ADEOS (pre-intervention) 2-3 weeks Patients watch an educational video clip and receive information leaflet Patient receives a followup phone call from the pharmacist 2-3 weeks Patients answer ADEOS (post-intervention)

Patient recruitment at selected pharmacy site Patients answer ADEOS (pre-intervention) 2-3 weeks Patients watch an educational video clip and receive information leaflet Patient receives a followup phone call from the pharmacist 2-3 weeks Patients answer ADEOS (post-intervention)

Patient recruitment at selected pharmacy site Patients answer ADEOS (pre-intervention) 2-3 weeks Patients watch an educational video clip and receive information leaflet Patient receives a followup phone call from the pharmacist 2-3 weeks Patients answer ADEOS (post-intervention)

Implications

What can we learn from this? Look beyond the paper case Reflect on co-op experiences and connect the dots Students learn to develop a system such as PASSAction to identify and resolve adherence issues as they enter real-world practice

The PASSAction Framework P Patients do not adhere to bisphosphonates ACTION Play the video in your community pharmacy A Complex administration requirements SS Design a patienteducation video

What can we learn from this? Understanding and addressing medication non-adherence is crucial in training pharmacy students to become patient-centered clinicians

Discussion Do you take medications or know of anyone who does? How can you apply the PASSAction framework to identify and resolve any adherence issues? Additional examples: Patient misunderstands instructions: take with food Patient recently diagnosed with diabetes and prescribed 6 new medications As a result of a shortage of a combination drug, a patient began receiving the medication as its 2 component parts

Guiding Pharmacy Students To Adopt A Patient-Centered Practice: Presented by: Vivian Lee BScPhm candidate UW School of Pharmacy Faculty supervisor: Certina Ho Adjunct Clinical Professor UW School of Pharmacy Exploring The Problem Of Medication Non-Adherence