Introduction to Sanofi and Genzyme 495/MetroWest Partnership's Conference Panel December 15, 2015 Michelle Multiple Sclerosis Denmark
Overview Who is Sanofi? Who is Genzyme MetroWest Investment Talent Real Estate Community Relations 2
Who is Sanofi? Sanofi is a global healthcare leader focused on patients needs: engaged in the research, development, manufacturing and marketing of therapeutic solutions focused on patients needs. Sanofi has core strengths in diabetes solutions, human vaccines, innovative drugs, consumer healthcare, emerging markets, animal health and Genzyme. 4 th largest pharmaceutical group in the world Headquartered in France 3
SANOFI AT A GLANCE More than 110,000 employees Present in 100 countries Our mission We act with our partner to protect health, enhance life and respond to the hopes and potential healthcare needs of 7 billion people around the word. 3 Commitments Exploring the boundaries of medical innovation for patients Preventing disease and supporting patients Improving access to healthcare 33.8 million In sales 2014 3 business segments Pharma Human vaccines Animal Health CORPORATE PRESENTATION 2015 4
PHARMA HUMAN VACCINES ANIMAL HEALTH SANOFI AT A GLANCE OUR 3 BUSINESS SEGMENTS > Diabetes > Cardiovascular disease > Rare diseases > Multiple sclerosis > Oncology > Consumer Health care > Generics > Pediatric vaccines > Influenza vaccines > Booster vaccines for adults and adolescents > Meningitis vaccines >Vaccines for travelers and endemic areas PHARMA PRODUCTS > Anti-parasitics > Anti-infectives > Anti-inflammatories > Anti-ulceratives VACCINES > Foot and mouth disease > Rabies and pets vaccines Range > Avian vaccines Net sales 27,720 M Net sales 3,974 M Net sales 2,076 M G. Blonsky/Capa Pictures CORPORATE PRESENTATION 2015 5
GROWTH PLATFORMS Emerging markets Diabetes solutions Vaccines Consumer Healthcare Animal Health Genzyme Other Innovative Products 33.8 million In sales in 2014 112 Industrial sites in 41 countries present in more than 100 countries more than 110 000 employees R&D A major biopharmacy player 45% of revenues generated by biologics 80% of development projects are biologics Information of December 31 st 2013
Who is Genzyme? A pioneer of the biotechnology movement in the early 1980s, Genzyme has always been driven by cutting-edge science and a commitment to treating unmet medical needs. Genzyme has pioneered the development and delivery of transformative therapies for over 30 years. Founded in 1981 in Boston, Massachusetts, Genzyme evolved from a tiny start-up with just a handful of employees to one of the world's leading biotech companies. Acquired by Sanofi in 2011, Genzyme now benefits from the reach and resources of one of the world s largest pharmaceutical companies, with a shared commitment to improving the lives of patients. Genzyme has long been known for our expertise in the class of rare genetic diseases known as lysosomal storage disorders (LSDs). We have also expanded through both in-house development and strategic acquisitions and partnerships to other disease areas such as thyroid cancer and multiple sclerosis 7 Generated 2,604 million in Sales for 2014, an increase of 24%
Rare Diseases Lysosomal Storage Disorders (LSDs) are the cornerstone of Genzyme's rare disease business Leverage our legacy to expand our expertise in additional therapeutics areas Innovative partnership with Alnylam focused on RNAi Sol Pompe disease Eva & Alberto Fabry disease THEREAPEUTIC AREAS Hematology Nephrology Neurology Pediatric Endocrinology Other TREATMENT AREAS Gaucher disease type 1 Pompe disease MPS I & II disease Fabry disease Thyroid cancer Homozygous Familial Hypercholesterolemia
Multiple Sclerosis Shani MS Tiger MS Once-daily oral therapy for relapsing remitting MS Infusion therapy for relapsing remitting MS 2 annual treatment courses MS business unit launched with the approval of two new therapies in 2013 Unique, personalized approach to patient care Strong early-stage MS pipeline focused on targeted immunomodulation, neuroprotection, remylenation, and progressive MS
MA Landscape: Genzyme s Impact Sanofi Genzyme is the largest Bio-Pharma employer in Massachusetts, with a combined 5,000 Sanofi Genzyme employees. Genzyme consistently ranks as one of the top charitable companies in Massachusetts, leading the Bio-Pharma industry. Genzyme s footprint stretches beyond the traditional center of Kendall Square, with sites in Allston, Framingham, Westborough and Northborough. 10
Sanofi Genzyme MetroWest Facts! Located in 19 buildings 2300 full time employees Real estate capacity to support an additional ~1100 employees Dedicated R&D Center and Manufacturing Operations Top 3 sources of talent finding: Internal Referral Direct Filled ~370 of the ~540 open positions 2015 11
Genzyme Northborough Operation Center (gnoc) Located in Northborough, Massachusetts Nearly 20 Acres of property with a 20 year lease. Over 200,000 square feet of warehouse space, fully equipped to meet the growth of Genzyme and meeting Quality standards Approximately 200 employees 13
gnoc Facts Total Size: 254,095 sq ft 2 TSA Certified Cargo Screening Areas 24/7 Full-Perimeter Security 2 Megawatt Diesel Backup Generator Materials Operations Warehouse 134,813 sq ft CRT 4,350 pallets 2-8C 791 pallets -20C 316 pallets Receiving 9 docks Shipping 6 docks Offices 1,202 sq ft Clinical Supplies Warehouse CRT Offices 10,160 sq ft 654 pallets 5,923 sq ft Quality Control Raw Materials Warehouse 10,197 sq ft CRT 480 pallets Lab 3,200 sq ft Sampling suite 2,000 sq ft Office 4,326 sq ft Labeling & Packaging GroupPackaging Suite 9,194 sq ft 2-8C 500 sq ft Offices 5,923 sq ft 14
Cerezyme Fabrazyme Myozyme / Lumizyme Clolar Thyrogen Aldurazyme Elaprase SepraFilm LeGoo Hyaluronic Acid (HA) Materials Support
Genzyme in Westborough Moved into One Research Drive from Framingham on November 21, 2014 500 employees working across multiple functions: Genzyme Industrial Operations Global Leadership and support functions Genzyme Corporate Quality Operations and Global Quality Leadership Sanofi Information Solutions Sanofi Human Resources (including Staffing) Sanofi Regulatory Affairs and Procurement Employee Volunteerism
Community Relations Our Community Relations mission is to have a lasting positive impact where our employees live and work, by building sustainable partnerships through a combination of financial contributions and employee involvement. Employee Volunteerism Health+ Access Good Neighbors Science Education
Dedicated and Committed Community Relations Mission in MetroWest! In 2014, Genzyme awarded ~$125,000 in grants/sponsorships to MetroWest Organizations Genzyme Science Kids program at Fuller Middle School Boys and Girls Club of MetroWest Big Brothers Big Sisters of Central Mass MetroWest Community Farms Outreach Family Promise MetroWest Framingham Public Library Habitat for Humanity of MetroWest/Worcester MetroWest Free Medical Program Ashland Fire Department Association 18
19 Thank You!