Creation Date 01-Nov-2011 Revision Number 1 1. IDENTIFICATION OF THE SUBSTANCE/MIXTURE AND OF THE COMPANY/UNDERTAKING Product Name Cat No. R40134, R40217, R40219 Synonyms Recommended Use Laboratory chemicals Company Remel 12076 Santa Fe Drive Lenexa, KS 66215 United States Telephone: 1-800-255-6730 Fax:1-800-621-8251 Entity / Business Name Oxoid Ltd. Wade Road Basingstoke, Hants, UK RG24 8PW Telephone: +44 (0) 1256 841144 E-mail address mbd-sds@thermofisher.com Emergency Telephone Number Carechem 24: +44 (0) 1865 407333 2. HAZARDS IDENTIFICATION The preparation is classified as dangerous in accordance with Directive 1999/45/EC. R-phrase(s) R11 - Highly flammable R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed R68/20/21/22 - Harmful: possible risk of irreversible effects through inhalation, in contact with skin and if swallowed 3. COMPOSITION/INFORMATION ON INGREDIENTS Haz/Non-haz Component Weight % EC-No. Classification Ethyl alcohol 85 EEC No. 200-578-6 F; R11 64-17-5 Methyl alcohol 67-56-1 5 EEC No. 200-659-6 F; R11 T; R23/24/25-39/23/24/25 Isopropyl alcohol 67-63-0 5 EEC No. 200-661-7 F; R11 Xi; R36 R67 Page 1 / 11
Acetic acid 64-19-7 0.5 EEC No. 200-580-7 R10 C; R35 For the full text of the R phrases mentioned in this Section, see Section 16 4. FIRST AID MEASURES Eye Contact Contact Ingestion Inhalation Notes to Physician Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician Wash off immediately with soap and plenty of water while removing all contaminated clothes and shoes Get medical attention. Clean mouth with water and drink afterwards plenty of water. Do not induce vomiting. Move to fresh air. Get medical attention if symptoms occur.. Treat symptomatically. Suitable Extinguishing Media CO2, dry chemical, dry sand, alcohol-resistant foam. 5. FIRE-FIGHTING MEASURES Extinguishing media which must not be used for safety reasons Do not use a solid water stream as it may scatter and spread fire Specific Hazards Arising from the Chemical Flammable. Keep product and empty container away from heat and sources of ignition. Protective Equipment and Precautions for Firefighters As in any fire, wear self-contained breathing apparatus pressure-demand, MSHA/NIOSH (approved or equivalent) and full protective gear Flash Point 18.33 C / 65 F Method Closed cup Autoignition Temperature Page 2 / 11
6. ACCIDENTAL RELEASE MEASURES Personal Precautions Environmental Precautions Methods for Containment and Clean Up Remove all sources of ignition. Use personal protective equipment. Ensure adequate ventilation. Do not flush into surface water or sanitary sewer system. Soak up with inert absorbent material Clean contaminated surface thoroughly 7. HANDLING AND STORAGE Handling Storage Specific use(s) Ensure adequate ventilation. Avoid contact with skin, eyes and clothing. Keep away from open flames, hot surfaces and sources of ignition. Keep away from heat and sources of ignition. Keep containers tightly closed in a cool, wellventilated place. 8. EXPOSURE CONTROLS/PERSONAL PROTECTION Exposure limits Component European Union The United Kingdom Ethyl alcohol TWA: 1000 ppm TWA; 1920 mg/m 3 TWA WEL - STEL: 3000 ppm STEL; 5760 mg/m 3 STEL Belgium France Spain Germany TWA: 1000 ppm 8 TWA: 1907 mg/m 3 8 VME: 1000 ppm 8 heures. VME: 1900 mg/m 3 8 heures. VLCT: 5000 ppm VLCT: 9500 mg/m 3 VLA-ED: 1000 ppm 8 horas VLA-ED: 1910 mg/m 3 8 horas 500 ppm TWA; 960 mg/m 3 TWA Page 3 / 11
Component European Union The United Kingdom Methyl alcohol hr WEL - TWA: 200 TWA: 260 mg/m 3 8 ppm TWA; 266 hr mg/m 3 TWA WEL - STEL: 250 ppm STEL; 333 mg/m 3 STEL Isopropyl alcohol STEL: 500 ppm 15 min STEL: 1250 mg/m 3 15 min TWA: 400 ppm 8 hr TWA: 999 mg/m 3 8 hr Acetic acid - STEL: 37 mg/m 3 STEL: 15 ppm TWA: 10 ppm TWA: 25 mg/m 3 Belgium France Spain Germany TWA: 266 mg/m 3 8 STEL: 250 ppm 15 STEL: 333 mg/m 3 15 TWA: 500 mg/m 3 8 STEL: 400 ppm 15 STEL: 1000 mg/m 3 15 TWA: 10 ppm 8 TWA: 25 mg/m 3 8 STEL: 15 ppm 15 STEL: 38 mg/m 3 15 VME: 200 ppm 8 heures. restrictive limit VME: 260 mg/m 3 8 heures. restrictive limit VLCT: 1000 ppm VLCT: 1300 mg/m 3 VLCT: 400 ppm VLCT: 980 mg/m 3 VLA-ED: 200 ppm 8 horas VLA-ED: 266 mg/m 3 8 horas VLA-EC: 500 ppm 15 minutos VLA-EC: 1250 mg/m 3 15 minutos VLA-ED: 400 ppm 8 horas VLA-ED: 998 mg/m 3 8 horas VLCT: 10 ppm VLCT: 25 mg/m 3 VLA-EC: 15 ppm 15 minutos VLA-EC: 37 mg/m 3 15 minutos VLA-ED: 10 ppm 8 horas VLA-ED: 25 mg/m 3 8 horas 200 ppm TWA; 270 mg/m 3 TWA absorber MAK: 200 ppm 8. MAK: 500 mg/m 3 8. Peak: 400 ppm Peak: 1000 mg/m 3. exposure factor 2 TWA: 500 mg/m 3 8. exposure factor 2 MAK: 10 ppm 8. MAK: 25 mg/m 3 8. Peak: 20 ppm Peak: 50 mg/m 3 TWA: 10 ppm 8. exposure factor 2 TWA: 25 mg/m 3 8. exposure factor 2 Component Italy Portugal The Netherlands Finland Austria Ethyl alcohol TWA: 1000 ppm 8 horas STEL: 1900 mg/m 3 15 TWA: 260 mg/m 3 8 TWA: 1000 ppm 8 TWA: 1900 mg/m 3 8 STEL: 1300 ppm 15 STEL: 2500 mg/m 3 15 STEL: 2000 ppm 15 STEL: 3800 mg/m 3 15 MAK: 1000 ppm 8 MAK: 1900 mg/m 3 8 Page 4 / 11
Component Italy Portugal The Netherlands Finland Austria Methyl alcohol ore. TWA: 260 mg/m 3 8 ore. STEL: 250 ppm 15 minutos horas Isopropyl alcohol STEL: 400 ppm 15 minutos horas Acetic acid - STEL: 15 ppm 15 minutos TWA: 10 ppm 8 horas STEL: 520 mg/m 3 15 TWA: 260 mg/m 3 8 MAC-TGG 25 mg/m 3 TWA: 270 mg/m 3 8 STEL: 250 ppm 15 STEL: 330 mg/m 3 15 TWA: 500 mg/m 3 8 STEL: 250 ppm 15 STEL: 620 mg/m 3 15 TWA: 5 ppm 8 TWA: 13 mg/m 3 8 STEL: 10 ppm 15 STEL: 25 mg/m 3 15 STEL: 800 ppm 15 STEL: 1040 mg/m 3 15 MAK: 200 ppm 8 MAK: 260 mg/m 3 8 STEL: 800 ppm 15 STEL: 2000 mg/m 3 15 MAK: 200 ppm 8 MAK: 500 mg/m 3 8 STEL: 20 ppm 15 STEL: 50 mg/m 3 15 MAK: 10 ppm 8 MAK: 25 mg/m 3 8 Component Switzerland Poland Norway Ireland Denmark Australia Ethyl alcohol STEL: 1000 ppm 15 NDS: 1900 mg/m 3 8 TWA: 500 ppm 8 TWA: 1000 ppm 8 TWA: 1000 ppm 8 TWA: 1000 ppm godzinach hr. TWA: 1880 mg/m 3 STEL: 1920 mg/m 3 TWA: 950 mg/m 3 8 TWA: 1900 mg/m 3 8 TWA: 1900 mg/m 3 8 15 MAK: 500 ppm 8 MAK: 960 mg/m 3 8 STEL: 625 ppm 15 minutter. STEL: 1187.5 mg/m 3 15 minutter. hr. Page 5 / 11
Component Switzerland Poland Norway Ireland Denmark Australia Methyl alcohol STEL: 800 ppm 15 STEL: 1040 mg/m 3 15 MAK: 200 ppm 8 MAK: 260 mg/m 3 8 NDSCh: 300 mg/m 3 15 minutach NDS: 100 mg/m 3 8 godzinach TWA: 100 ppm 8 TWA: 130 mg/m 3 8 STEL: 150 ppm 15 minutter. STEL: 162.5 mg/m 3 15 minutter. hr. TWA: 260 mg/m 3 8 hr. TWA: 260 mg/m 3 8 STEL: 250 ppm STEL: 328 mg/m 3 TWA: 200 ppm TWA: 262 mg/m 3 Isopropyl alcohol STEL: 400 ppm 15 STEL: 1000 mg/m 3 15 MAK: 200 ppm 8 MAK: 500 mg/m 3 8 Acetic acid STEL: 20 ppm 15 STEL: 50 mg/m 3 15 MAK: 10 ppm 8 MAK: 25 mg/m 3 8 NDSCh: 1200 mg/m 3 15 minutach NDS: 900 mg/m 3 8 godzinach NDSCh: 30 mg/m 3 15 minutach NDS: 15 mg/m 3 8 godzinach TWA: 100 ppm 8 TWA: 245 mg/m 3 8 STEL: 150 ppm 15 minutter. STEL: 306.25 mg/m 3 15 minutter. TWA: 10 ppm 8 TWA: 25 mg/m 3 8 STEL: 20 ppm 15 minutter. STEL: 37.5 mg/m 3 15 minutter. hr. STEL: 400 ppm 15 min TWA: 10 ppm 8 hr. TWA: 25 mg/m 3 8 hr. STEL: 15 ppm 15 min STEL: 37 mg/m 3 15 min TWA: 490 mg/m 3 8 TWA: 10 ppm 8 TWA: 25 mg/m 3 8 STEL: 500 ppm STEL: 1230 mg/m 3 TWA: 400 ppm TWA: 983 mg/m 3 STEL: 15 ppm STEL: 37 mg/m 3 TWA: 10 ppm TWA: 25 mg/m 3 Occupational exposure controls Engineering Measures Personal Protective Equipment Respiratory Protection Eye Protection and body protection Hand Protection Ensure adequate ventilation, especially in confined areas Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced Tightly fitting safety goggles Long sleeved clothing. Chemical resistant apron. Antistatic boots. Impervious gloves. Protective gloves Hygiene Measures Environmental exposure controls When using, do not eat, drink or smoke. Provide regular cleaning of equipment, work area and clothing. 9. PHYSICAL AND CHEMICAL PROPERTIES Physical State Appearance ph Boiling Point/Range Melting Point/Range Liquid Clear Colourless Page 6 / 11
9. PHYSICAL AND CHEMICAL PROPERTIES Flash Point 18.33 C / 65 F Method Closed cup 10. STABILITY AND REACTIVITY Stability Conditions to Avoid Incompatible Materials Hazardous Decomposition Products Hazardous Polymerization Hazardous Reactions. Stable under recommended storage conditions. Heat, flames and sparks. Strong oxidizing agents Carbon oxides No information available None under normal processing. 11. TOXICOLOGICAL INFORMATION Acute Toxicity Product Information Harmful by inhalation, in contact with skin and if swallowed Component Information Component LD50 Oral LD50 Dermal LC50 Inhalation Ethyl alcohol 7060 mg/kg ( Rat ) 20000 ppm/10h ( Rat ) Methyl alcohol 5628 mg/kg ( Rat ) 15800 mg/kg ( Rabbit ) 64000 ppm ( Rat ) 4 h 83.2 mg/l ( Rat ) 4 h Isopropyl alcohol 4396 mg/kg ( Rat ) 12800 mg/kg ( Rat ) 72.6 mg/l ( Rat ) 4 h 12870 mg/kg ( Rabbit ) Acetic acid 3310 mg/kg ( Rat ) 1060 mg/kg ( Rabbit ) 11.4 mg/l ( Rat ) 4 h Chronic Toxicity Carcinogenicity The table below indicates whether each agency has listed any ingredient as a carcinogen Component IARC UK Ethyl alcohol Group 1 IARC: (International Agency for Research on Cancer) IARC: (International Agency for Research on Cancer) Group 1 - Carcinogenic to Humans Group 2A - Probably Carcinogenic to Humans Group 2B - Possibly Carcinogenic to Humans Page 7 / 11
Sensitization Neurological Effects Mutagenic Effects Reproductive Effects Developmental Effects Target Organs Blood, Liver, Respiratory system, Central nervous system (CNS), Eyes, Reproductive System, Gastrointestinal tract (GI),, Optic nerve. 12. ECOLOGICAL INFORMATION Ecotoxicity. Component Freshwater Algae Freshwater Fish Microtox Water Flea Ethyl alcohol Leucidus idus: LC50 = 8.14 mg/l/48h Methyl alcohol Isopropyl alcohol 1000 mg/l EC50 > 72 h 1000 mg/l EC50 > 96 h Pimephales promelas: LC50 > 10000 mg/l 96h 1400000 µg/l LC50 96 h 9640 mg/l LC50 96 h 11130 mg/l LC50 96 h phosphoreum:ec50 = 34634 mg/l/30 min phosphoreum:ec50 = 35470 mg/l/5 min EC50 = 39000 mg/l 25 min EC50 = 40000 mg/l 15 min EC50 = 43000 mg/l 5 min = 35390 mg/l EC50 phosphoreum 5 min EC50 = 9268 mg/l/48h EC50 = 10800 mg/l/24h EC50 > 10000 mg/l 24h 13299 mg/l EC50 = 48 h Acetic acid Pimephales promelas: LC50 = 88 mg/l/96h Lepomis macrochirus: LC50 = 75 mg/l/96h phosphoreum: EC50 = 8.8 mg/l/15 min phosphoreum: EC50 = 8.8 mg/l/25 min phosphoreum: EC50 = 8.8 mg/l/5 min EC50 = 95 mg/l/24h Persistence and Degradability No information available Bioaccumulative Potential Mobility Component log Pow Ethyl alcohol -0.32 Page 8 / 11
Component log Pow Methyl alcohol -0.74 Isopropyl alcohol 0.05 Acetic acid -0.2 13. DISPOSAL CONSIDERATIONS Waste from Residues / Unused Products Contaminated Packaging Dispose of as hazardous waste in compliance with local and national regulations Dispose of in accordance with local regulations. 14. TRANSPORT INFORMATION IMDG/IMO UN-No UN1170 Hazard Class 3 Packing Group II Proper Shipping Name ETHANOL SOLUTION ADR UN-No UN1170 Hazard Class 3 Packing Group II Proper Shipping Name ETHANOL SOLUTION IATA UN-No UN1170 Hazard Class 3 Packing Group II Proper Shipping Name ETHANOL SOLUTION 15. REGULATORY INFORMATION The preparation is classified as dangerous in accordance with Directive 1999/45/EC Labelling Page 9 / 11
R-phrase(s) R11 - Highly flammable R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed R68/20/21/22 - Harmful: possible risk of irreversible effects through inhalation, in contact with skin and if swallowed S-phrase(s) S 7 - Keep container tightly closed S16 - Keep away from sources of ignition. No smoking S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice S28A - After contact with skin, wash immediately with plenty of water S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible) S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection International Inventories Component EINECS ELINCS NLP TSCA DSL NDSL PICCS ENCS CHINA AICS KECL Ethyl alcohol 200-578-6 - X X - X X X X X Methyl alcohol 200-659-6 - X X - X X X X X Isopropyl alcohol 200-661-7 - X X - X X X X X Acetic acid 200-580-7 - X X - X X X X X 16. OTHER INFORMATION Full text of R-phrases referred to under sections 2 and 3 R10 - Flammable R11 - Highly flammable R35 - Causes severe burns R36 - Irritating to eyes R67 - Vapors may cause drowsiness and dizziness R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed R68/20/21/22 - Harmful: possible risk of irreversible effects through inhalation, in contact with skin and if swallowed R23/24/25 - Toxic by inhalation, in contact with skin and if swallowed R39/23/24/25 - Toxic: danger of very serious irreversible effects through inhalation, in contact with skin and if swallowed Page 10 / 11
Prepared By Creation Date Revision Date Revision Summary Restrictions on use Training advice Literary reference 16. OTHER INFORMATION Regulatory Affairs 01-Nov-2011 01-Nov-2011 "***", and red text indicates revision Disclaimer The information provided on this Safety Data Sheet is correct to the best of our knowledge, information and belief at the date of its publication. The information given is designed only as a guide for safe handling, use, processing, storage, transportation, disposal and release and is not to be considered as a warranty or quality specification. The information relates only to the specific material designated and may not be valid for such material used in combination with any other material or in any process, unless specified in the text. End of Safety Data Sheet Page 11 / 11