AOCC2021 Abstract Result

AOCC2021 Abstract Result Renumbered ID Category Title First Author Organization / Institution Result BA01 Efficacy and safety of upadacitinib induction therapy in patients with moderately to severely active : results from U-ACHIEVE study Min-Hu Chen Division of Gastroenterology, The First Affiliated of Sun Yat-sen Best Abstract Award BA02 Guselkumab induction therapy effect on endoscopic outcome measures in moderately-to-severely active Crohn s disease patients: week-12 results from phase-2 GALAXI-1 study Geert D Haens Amsterdam UMC, Amsterdam, The Netherlands Best Abstract Award BA03 Risankizumab therapy induces improvements in endoscopic endpoints in patients with moderate-to-severe Crohn s disease: results from two phase 3 studies Zhihua Ran Shanghai Jiao Tong Best Abstract Award BA04 Effect of ustekinumab maintenance on corticosteroid-free endoscopic and clinical outcomes in patients with Crohn's disease (CD) through 48-weeks: STARDUST trial Silvio Danese IBD Center, Humanitas Best Abstract Award BA05 COLLAGEN VI DERIVED FROM HUMAN INTESTINAL MYOFIBROBLASTS INCREASES T CELL ADHESION IN INFLAMMATORY BOWEL DISEASE; Si-Nan Lin Department of Gastroenterology and Hepatology, The First Affiliated of Sun Yat-sen Best Abstract Award BA06 A novel therapeutic strategy in through enforcing IL-22 production by ILC3 Yusuke Yoshimatsu Keio School of Medicine Best Abstract Award BA07 Olamkicept, a Novel IL-6 Trans-signaling Inhibitor, Induces Rapid Clinical Improvements in Moderate to Severe Ulcerative Colitis: Phase 2 Study Results Shenghong Zhang The First Affiliated, Sun Yat-sen Best Abstract Award BA08 Development of a machine learning model to distinguish between ulcerative colitis and Crohn s disease using RNA sequencing data Soo-Kyung Park Department of Internal Medicine, Kangbuk Samsung, Sungkyunkwan School of Medicine Best Abstract Award BA09 Single-cell atlas-based analysis of the origin of extracellular matrix in intestinal fibrosis in Crohn's disease Yao Zhang Ruijin, Shanghai Jiaotong School of Medicine Best Abstract Award BA10 Select food additives affect the growth of bacteria driving the inflammatory tenor of the mucosa-associated microbiome in Crohn s disease. The ENIGMA study. J.J. Jimenez Loayza The of Queensland Diamantina Institute, Faculty of Medicine Best Abstract Award DIA01 Efficacy and safety of ustekinumab for through 3 years: UNIFI long-term extension Maria Abreu of Miami Miller School of Medicine Distinguished Investigator Award DIA02 Efficacy and safety of vedolizumab versus adalimumab in Asian patients with : A post-hoc analysis of the VARSITY trial Joo Sung Kim Seoul National, Seoul National College of Medicine Distinguished Investigator Award DIA03 Decreased TMIGD1 Exacerbates Inflammation and Damages Intestinal Epithelial Barrier: A Novel Treatment Target in Crohn's Disease Longyuan Zhou The First Affiliated of Sun Yat-Sen Distinguished Investigator Award DIA04 Neural Adhesive Molecule LRRC4 in Enterica Glial Cells as a Potential Mucosal Barrier Modulator in Crohn s Disease Segmental Progression Xiaoxi Ma Department of Gastroenterology, The Sixth Affiliated, Sun Yat-sen, Guangzhou, PR China. Distinguished Investigator Award DIA05 CRL4(DCAF2) downregulation leads to epithelial barrier dysfunction and enhances susceptibility to inflammation Yu Zhang Sir Run run Shaw hospital, Zhejiang school of medicine Distinguished Investigator Award DIA06 Gene expression profiling in identifies characteristics for anti-tnf response and targets for alternative therapies Marietta Iacucci of Birmingham Distinguished Investigator Award DIA07 Post-marketing surveillance of tofacitinib in patients with in Japan: an interim report of safety data Katsuyoshi Matsuoka Internal Medicine, Toho Sakura Medical Center Distinguished Investigator Award DIA08 Food as a risk factor for the development and perpetuation of Crohn s Disease. The international ENIGMA cohort study. Gina L Trakman Department of Gastroenterology, St Vincent Distinguished Investigator Award DIA09 Pregnancy outcomes in women exposed to ustekinumab (UST) in the Crohn s disease (CD) and (UC) clinical trials Bincy Abraham Methodist Gastroenterology Associates Distinguished Investigator Award DIA10 ADSCs stimulated by VEGF-C alleviate intestinal inflammation via dual mechanisms of enhancing lymphatic drainage by VEGF-C/VEGFR-3 dependent mechanism and inhibition of NF-κB pathway by secretome Lei Zhang Department of Gastroenterology, Shanghai Tenth People s, Tongji School of Medicine Distinguished Investigator Award EO01 Prophylactic Antitubercular Therapy Aggravates Disease Behavior in Patients with Crohn s Disease Receiving Anti-TNF Therapy:a Multicenter Study Fen Liu of Sun Yat-sen, Guangzhou, China EO02 Outcome of patients with inflammatory bowel disease and concomitant ankylosing spondylitis: a cohort study from SNU IBD research group Yu Kyung Jun Seoul National Univertisity EO03 Impact of Biological Therapy on Healthcare Resource Utilization in Crohn's Disease Patients: A Population-based Cohort Study in Taiwan Nai-Yu Chen Chen School of Pharmacy, Institute of Clinical Pharmacy and Pharmaceutical Sciences, College of Medicine, National Cheng Kung EO04 Real-World Treatment Persistence of Vedolizumab in Inflammatory Bowel Disease Patients in Taiwan: Results From the TSIBD Registry (VIOLET Study) Wei-Chen Tai Division of Hepatogastroenterology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial EO05 Vedolizumab and Ustekinumab are equally effective in the treatment of Ulcerative Colitis irrespective of prior anti-tnf-alpha exposure Takashi Niwa Medicine, The Jikei EO06 Fingolimod (FTY720) ameliorates dextran sodium sulphate-induced colitis by beneficially modulating gut microbiome and alleviating necroptosis and fibrosis Han Hee Lee Division of Gastroenterology, Department of Internal Medicine, College of Medicine, The Catholic of Korea, Seoul, Republic of Korea EO07 The ization Burden of Inflammatory Bowel Disease in China: A Nationwide Study from 2013 to 2018 Yiming He The First Affiliated of Sun Yat-sen EO08 Crohn's disease patients who have never received biologic therapy or who are intolerant to infliximab may become the best response subgroup of adalimumab treatment: a single-center, 26-week cohort study Yubei Gu Department of gastroenterology, Ruijin hospital, School of medicine, Shanghai Jiao Tong,China EO09 Healthcare Cost of Inflammatory Bowel Disease in the First 8 Years After Diagnosis: A Territory-Wide Study in Hong Kong Joyce Wing Yan Mak The Chinese of Hong Kong EO10 Adding enteral nutrition to therapies improved histological remission of IBD--a retrospective analysis of 524 IBD patients in the real world Wu Lin Department of Gastroenterology and Hepatology, Jinling EO11 Incidence and risk of malignancy among elderly-onset inflammatory bowel disease: a prospective cohort study from China ZHENG WANG Department of Gastroenterology, PUMC, CAMS and PUMC EO12 The interaction of Th17 differentiations related gene polymorphisms and environmental factors contributing to the disease classification and outcomes of Crohn s disease in Chinese Han population EO13 The Role of TNFAIP3 in the Pathogenesis of Intestinal Inflammation Meiping Yu Gechong Ruan Peking Union Medical College Department of Gastroenterology, Tongji, Tongji EO14 SETD8 involved in the progression of IBD via epigenetically regulating P62/SQSTM1 expression Pin Chen Zhongnan of Wuhan EO15 Characterization of ectopic olfactory receptor, OR51E2 (Olf 78) expression in severe and DSS induced experimental colitis Namjoo Kim Department of Gastroenterology, Korea Guro, EO16 IL-33 Regulates The Development Of Inflammatory Bowel Disease Through Its Receptor ST2 In Enteric Glial Cells Kai Nie The Department of Gastroenterology in the third xiangya hospital of central south university EO17 Populational Diversity of Gut Microbiota in Southwest China in the Context of Urbanization; Yang Sun The First Affiliated of Kunming Medical. EO18 Distinct pattern of gut microbial dysbiosis in Crohn s Disease and intestinal tuberculosis A Machine Learning-based classification models. Aditya Bajaj All India Institute of Medical Sciences EO19 Integrative Analysis of Multi-omics Profiling - a novel framework for differentiating Crohn s disease from Intestinal tuberculosis Xiaojun Zhuang of Sun Yat-sen EO20 EO21 Prevotella copri promotes intestinal carcinogenesis through leucine dependent mtor-stat3 signaling pathway Child Gut Microbiota-secreted Extracellular Vesicles Enter into Liver to Protect against Gut Inflammation Exacerbated-Hepatic Steatosis;; Wu Xuemei General, Tianjin Medical Le Liu shenzhen hospial, southern medical university EO22 Metagenomic Analysis to Determine The Potential of Viral Infection in Intestinal Tissue as a Cause of Intestinal Inflammation Based on the Bioinformatics Pipeline Rifaldy Fajar Computational Biology Laboratory, Yogyakarta State, Indonesia EO23 Cyclosporine A inhibiting the formation of neutrophil extracellular traps via modulating the activity of G6PD in Ziping Ye The First Affiliated of Nanjing Medical

EO24 Undulating bile acids profiles suppressed colonic inflammation by shaping the plasticity of innate lymphoid cells in the mice with cholecystectomy Jun Xu Peking People's EO25 Excessive mitochondrial fission suppresses mucosal repair through impairing butyrate metabolism of colonocytes in UC Shichen Fu Qilu of Shandong EO26 Effect of guselkumab induction on early clinical outcome measures in patients with moderately-to-severely active Crohn s disease: results from GALAXI-1 study Silvio Danese Humanitas Research, Milan, Italy EO27 Ustekinumab safety in inflammatory bowel disease: pooled analysis through 5 years in Crohn s disease and 2 years in William J. Sandborn of California San Diego, La Jolla, CA, USA EO28 Ustekinumab safety in IBD: comprehensive analysis of major cardiovascular events in Crohn s disease (5 years) and (2 years) Subrata Ghosh Institute of Translational Medicine, College of Medical and Dental, Sciences, of Birmingham EO29 Response to biologics in ibd patients assessed by computerized image analysis of probe based confocal laser endomicroscopy with molecular labeling Marietta Iacucci of Birmingham EO30 Clinical, biochemical and molecular predictors of non-response to anti-tnf therapy in patients with IBD : A pilot study Peeyush Kumar All India institute of medical sciences EO31 Global hospitalization trends for Crohn s disease and : systematic review with temporal analyses Michael J. Buie of Calgary EO32 Classification of intestinal fibrosis in Crohn s disease patients using CT Enterography-based deep learning: comparisons with radiomics and radiologists Meng Jixin Department of Radiology, The First Affiliated of Sun Yat-Sen EO33 A better monitoring strategy for thiopurine-induced leukopenia in inflammatory bowel disease: NUDT15 C415T combined with DNA-thioguanine nucleotide level Xia Zhu Department of Gastroenterology, the Sixth Affiliated, Sun Yat-sen EO34 Association between endoscopic features and histopathological patterns of colorectal polyps in Cronkhite-Canada syndrome Qiushi Xu Peking Union Medical College EO35 Novel characteristics of scanning electric microscopy in Shun Tanemoto Novel characteristics of scanning electric microscopy in EO36 Predictive value of mesenteric fat alteration by intestinal ultrasound in Crohn s Disease during Infliximab Zicheng Huang The sixth affiliated hospital of Sun Yat-Sen university EO37 Allogeneic Umbilical Cord-derived Mesenchymal Stem Cells(TH-SC01) for the Treatment of Complex Perianal Fistulas in Perianal Crohn's Disease:a pilot study. Wei Juan Jinling hospital EO38 A study to estimate the proportion of inflammatory bowel disease patients needing biological agents and reasons for their discontinuation. Vinita Patil P D Hinduja National and Medical Research Center, Mahim EO39 The Development and Validation of Anti-Paratuberculosis-Nocardia Polypeptide Antibody [anti-ptnp] for the Diagnosis of Crohn s Disease Han Gao Department of Gastroenterology, The Shanghai Tenth People s of Tongji EO40 Artificial neural network analysis based immune-related signatures for primary infliximab non-responding patients with Xuanfu Chen Peking Union Medical College, Peking Union Medical College, Chinese Academy of Medical Sciences P001 Design and methodology of the prospective, multicentre, real-world study (VALUE) in China on the safety and effectiveness of vedolizumab Li Ma Takeda Pharmaceutical Company Limited P002 Tofacitinib for the treatment of : up to 7.8 years of safety data from global clinical trials William J Sandborn Division of Gastroenterology, of California San Diego P003 Worldwide post-marketing safety surveillance experience with tofacitinib in David T Rubin of Chicago Medicine Inflammatory Bowel Disease Center P004 Reasons and Factors Contributing to Chinese Patients Preference for Ustekinumab in Crohn s Disease: A Multicenter Cross-sectional Study Lingya Yao Sir Run Run Shaw, College of Medicine Zhejiang P005 Steroid-free remission in patients with receiving tofacitinib in real clinical practice.;;; Anna Kagramanova Moscow Clinical Scientific Center named after a. s. Loginov P006 Exclusive Enteral Nutrition Regulates the Intestinal Flora in Patients with Active Crohn s Disease Jingjing Jiang Medical School of Southeast P007 The Correlation between Serum Fatty Acid Profile and Activity of Inflammatory Bowel Disease Shuyu Jiang Medical School of Southeast P008 Autosomal recessive 333 base pair Interleukin 10 receptor alpha subunit deletion in very early-onset inflammatory bowel disease Jia-jia Lv Dept. of Pediatrics, Ruijin, Shanghai Jiao Tong, School of Medicine P009 Atrial Natriuretic Peptide Attenuates colitis via the cgas-sting Pathway in Intestinal Epithelial Cells Chaoyue Chen Department of Gastroenterology, Union, Tongji P010 The effectiveness of the optimized scheme of therapy with ustekinumab in patients with Crohn's disease with previous anti-tnf therapy Oleg Knyazev Moscow Scientific Center named after A. S. Loginov P011 Anti-inflammation therapy with HMGB1 A box via liposome to LPS stimulated macrophages and DSS-induced colitis via HMGB1/TLR4/NF-κB pathway Wensong Ge Department of Gastroenterology, Xinhua, School of Medicine, Shanghai Jiao Tong P012 Anxiety and depression in patients with inflammatory bowel diseases at the Moscow Clinical Research Center named after A. S. Loginov Oleg Knyazev Moscow Scientific Center named after A. S. Loginov P013 TOB1 blocks intestinal mucosal inflammation through inducing ID2-mediated suppression of Th1/Th17 cell immune responses in IBD Ritian Lin The Shanghai Tenth People's of Tongji P014 An analysis of non-melanoma skin cancer rates in the tofacitinib clinical program Bruce E Sands Dr. Henry D. Janowitz Division of Gastroenterology, Icahn School of Medicine at Mount Sinai P015 Patients views of shared decision making in IBD: An investigation in China Dingting Xu P016 Usefulness of Transabdominal Ultrasonography in Immune-Mediated Colitis Kensuke Sakurai The Second Affiliated, School of Medicine, Zhejiang Department of Gastroenterology and Hepatology, Hokkaido Graduate School of Medicine P017 Real-world pattern of biologic use in patients with inflammatory bowel disease: the Taiwan Society of Inflammatory Bowel Disease (TSIBD) study Wei-Chen Lin Division of Gastroenterology, Department of Internal Medicine, Mackay Memorial, Taipei, Taiwan P018 Association between efficacy outcomes and prior duration of remission in patients with receiving tofacitinib: 6-month data from RIVETING Marla C Dubinsky Icahn School of Medicine at Mount Sinai P019 Pharmacokinetics (PK), Safety, and Tolerability of Etrasimod in Participants With Mild, Moderate, or Severe Hepatic Impairment: Single-dose, Open-label, Parallelgroup Study Caroline A. Lee Arena Pharmaceuticals, Inc. P020 Characteristics of fecal microbiota to predict postoperative endoscopic recurrence in patients with Crohn s disease Haichao Wang Department of Gastroenterology, Shanghai Tenth People s, Tongji School of Medicine P021 Identifying patients with Crohn s disease at high risk of primary nonresponse to infliximab therapy using a radiomic-clinical nomogram Xuehua Li Department of Radiology, The First Affiliated, Sun Yat-Sen P022 Effect of Etrasimod on Circulating Lymphocyte Subsets: Data From a Randomized Phase 1 Study in Healthy Japanese and Caucasian Men H. Kiyomi Komori Arena Pharmaceuticals, Inc. P023 Targeting Type Ⅰ Collagen to Stage the Progression of Fibrosis in Crohn s Disease Using MR Imaging Probe Baolan Lu Targeting Type Ⅰ Collagen to Stage the Progression of Fibrosis in Crohn s Disease Using MR Imaging Probe P024 An Escherichia coli strain with extra catalase activity protects against murine colitis by scavenging hydrogen peroxide and regulating regulatory t cell/interleukin-17 pathways Da Hye Kim Department of Internal Medicine and Institute of Gastroenterology, Yonsei College of Medicine P025 Ferroptosis of intestinal epithelial cells in Xinyu Bai The First Affiliated of Kunming Medical P026 Loss of Response and Requirement of Ustekinumab Dose Escalation in Inflammatory Bowel Diseases: A Systematic Review with Meta-analysis Hongsheng Yang the Sixth Affiliated of Sun Yat-sen P027 Incidence and risk factors of venous thromboembolism in inpatients with inflammatory bowel disease. Yasuhiro Aoki Internal Medicine, Keio School of Medicine, Tokyo, Japan. P028 IL-17 dependent fibroblastic reticular cell training alleviates pathogen induced colitis Dongwen Wu Central South, Gastrointestinal department, Xiangya

P029 Early Infliximab Trough Levels Predict Long-term Efficacy of Infliximab in a Randomized Controlled Trial in Patients with Active Crohn's Disease Comparing between CT-P13 and Originator Infliximab J. Park Yonsei College of Medicine P030 UCEIS is superior to MES and DUBLIN scores in evaluating the clinical prognosis of patients with Chenxi Xie Zhongshan Affiliated to Xiamen P031 A new structure-based sonographic parameter for estimating endoscopic remission in : submucosa index (SMI) Jun Miyoshi Kyorin School of Medicine Department of Gastroenterology and Hepatology P032 Anti-TNF-αMonoclonal Antibody Therapy Improves Anemia through Downregulating Hepatocyte Hepcidin Expression in Inflammatory Bowel Disease. Weigang Shu Shanghai Tenth People's P033 An assessment of additional training requirements for professional endoscopists to facilitate accurate diagnosis of inflammatory bowel diseases Dong Yang the First of Jilin P034 Development and validation of Mucosal Healing prediction algorithm for evaluating Crohn's disease: a retrospective multicenter cohort study; Nana Tang Jiangsu P035 Serum and fecal oncostatin M are noninvasive biomarkers of disease monitoring and infliximab response in inflammatory bowel disease Ying Cao Zhejiang School of Medicine Second Affiliated P036 Tofacitinib for the treatment of : analysis of malignancy rates from the clinical program Ryan C Ungaro Dr. Henry D. Janowitz Division of Gastroenterology, Icahn School of Medicine at Mount Sinai P037 Hepatitis B virus reactivation risk in patients with immune-mediated inflammatory disease receiving biologics Soo Min Ahn Department of Rheumatology, Asan Medical Center P038 Correlation Analysis between Coagulation Dysfunction and the Activity of Inflammatory Bowel Disease Yaqi Zhao The 1st affiliated hospital of Dalian Medical P039 Analysis of Anxiety and Depression Status and Its Correlation with Inflammatory Cytokines in Patients with Inflammatory Bowel Disease Mengyuan Xu The 1st affiliated hospital of Dalian Medical P040 Clinical Significance of Serum Antibody Detection in Patients with Inflammatory Bowel Disease Xia Tan The 1st affiliated hospital of Dalian Medical P041 Safety and Efficacy of Granulocyte and Monocyte Adsorption Apheresis in Patients With Ulcerative Colitis Ke qiu Qu The 1st affiliated hospital of Dalian Medical P042 Influence of GMA on Serum Cytokines in Patients with Ulcerative Colitis Ning Liu The 1st affiliated hospital of Dalian Medical P043 Clinical Significance and Monitoring of Infliximab Trough Levels and Anti- Infliximab Antibodies in Patients with Inflammatory Bowel Disease Xiu xue Hao The 1st affiliated hospital of Dalian Medical P044 Treatment of moderate to severe by using granulocyte and monocyte adsorption apheresis(gma) to evaluate its efficacy and safety A report of 8 cases Qing Zhao The 1st affiliated hospital of Dalian Medical P045 GMA vs. Infliximab for moderate to severe active : a retrospective observational study Yu Chen The 1st affiliated hospital of Dalian Medical P046 The Prevalence of Extraintestinal Manifestations in IBD Kashif Iftikhar The 1st affiliated hospital of Dalian Medical P047 Crohn s disease of the oesophagus: Case report and literature review JAYVIN SOBUN The 1st affiliated hospital of Dalian Medical P048 A Retrospective Study for Evaluation of Inflammatory Activity in UC Patients, A Report of 30 Cases Jawad Ali The 1st affiliated hospital of Dalian Medical P049 Clinical Significance of D-dimer, PT, FIB and PLT in Patients with Ulcerative Colitis Shengping Chu The 1st affiliated hospital of Dalian Medical P050 Treatment of Inflammatory bowel disease Using Tumour Necrosis Factor Alpha Inhibitors (Infliximab) A report of 28 cases Satya Singh The 1st affiliated hospital of Dalian Medical P051 Clinical Diagnostic Value of Perinuclear Anti-neutrophil Antibody and Antiintestinal Goblet Cell Antibody in Ulcerative Colitis Wenhui Zhu The 1st affiliated hospital of Dalian Medical P052 The Initial Establishment of Access Database for Ulcerative Colitis Xiuli Chen The 1st affiliated hospital of Dalian Medical P053 A Retrospective Analysis of 294 Patients with Ulcerative Colitis Juan Chen The 1st affiliated hospital of Dalian Medical P054 Therapeutic Effect of 5-ASA-loaded SiO2 Nanoparticles Targeting on Ulcerative Colitis in Mice Dan Xiang The 1st affiliated hospital of Dalian Medical P055 Clinical study on Saccharomyces boulardii in the Treatment Of Patients with Mild to Moderate Ulcerative Colitis Hao Wu The 1st affiliated hospital of Dalian Medical P056 The Colonic Expression of Flt3 and Flt3L in The Mice Model of Ulcerative Colitis Yushuang Huang The 1st affiliated hospital of Dalian Medical P057 The protective role of AE-941(Neovastate)on in rats Xiaomei He The 1st affiliated hospital of Dalian Medical P058 Effect of Etiasa on the Expression of MMP-2 and TNF-α in Rat Model of Ulcerative Colitis Gongjun Wang The 1st affiliated hospital of Dalian Medical P059 Clinical Significance of Fecal Calprotectin in Ulcerative Colitis and Irritable Bowel Syndrome Ying Zhang The 1st affiliated hospital of Dalian Medical P060 Expression and Implication of Human β-defensin 2 in Ulcerative Colitis Li Yang The 1st affiliated hospital of Dalian Medical P061 Expression and Significance of HNP1-3 in Ulcerative Colitis Xiaoyan Xu The 1st affiliated hospital of Dalian Medical P062 Desulfovibrio vulgaris flagellin exacerbates experimental colitis through LRRC19 signaling Runxiang Xie Department of Gastroenterology and Hepatology, General, Tianjin Medical P063 α-glycyrrhizic acid prevents obesity in high-fat diet mice through regulation of gut microbiota and bile acid metabolism Huiqin Hou Tianjin Medical General P064 Lactobacillus rhamnosus GG colonization in early life regulates gut-brain axis and relieves anxiety-like behavior in adulthood Bingqian Zhou Department of Gastroenterology and Hepatology, General, Tianjin Medical Universit P065 The microbiome profile in and pouchitis Xin Gao Tianjin medical universit general hospital P066 Combined serological antibodies differentiate non-ibd, Crohn's disease, and patients. YUAN Baisi Jinling hospital P067 Continued Postoperative Use of Tumor Necrosis Factor-α ;Inhibitors for the Prevention of Crohn's Disease Recurrence Jongwook Yu Yonsei College of Medicine P068 Therapeutic Effect of Indirubin-loaded Bovine Serum Albumin Nano-particles on Ulcerative Colitis Guang-Min Yu Department of Gastroenterology, the Third Affiliated of Guangzhou Medical P069 Microbial Changes in Stool, Saliva, Serum, and Urine Before and After Anti-Tumor Necrosis Factor-α Therapy in Patients with Inflammatory Bowel Diseases Yong Eun Park Division of Gastroenterology, Department of Internal Medicine, Inje College of Medicine, Haeundae Paik, Republic of Korea P070 Short-term outcomes of isoperistaltic side-to-side anastomosis (ISSA) in Crohn s disease Wenhao Chen Colorectal Surgery Department, Zhongnan of Wuhan P071 Short-term tolerability and effectiveness of methotrexate monotherapy in adult patients with Crohn's disease: A retrospective study Hee Seung Hong Department of Gastroenterology, Asan Medical Center P072 A case report and literature review: Rectal inflammatory myofibroblastic tumor Hyung-Hoon Oh Chonnam National Medical School P073 Lactobacillus rhamnosus GG/p40 and vitamin D3 play a synergistic protective role on mice colitis by promoting vitamin D receptor expression Dan Chen Peking Union Medical College

P074 Peripheral blood DNA methylation profiles predict Ustekinumab response and remain stable during induction and maintenance treatment in moderate-severe Crohn s disease patients. Vincent Joustra Amsterdam UMC location AMC P075 Medication Belief is associated with improved Adherence to Exclusive Enteral Nutrition in Patients with Crohn s Disease Shuyan Li The Second Affiliated,Zhejiang School of Medicine P076 Comparison of Clinical Outcomes between Radiological and Endoscopic Strictures in Ileocolonic Crohn's Disease: Which Types of Bowel Strictures Require More Attention from Clinician? LI SHI Department of Radiology, The First Affiliated,Sun Yat-Sen P077 P078 P079 P080 Association between Helicobacter pylori infection and Inflammatory Bowel Disease in Children: A Systematic Review and Meta-Analysis Fecal Microbiota Transplantation Ameliorates Experimental Colitis By Regulating Autophagy Sodium Butyrate Ameliorates Dextran Sulfate Sodium Induced Colitis In Mice By Regulating Gut Microbiota Analysis of Treatment Status of Crohn's Disease in Southeast China in Recent 11 Years GUIPING KONG Haoming Xu Haoming Xu Department of Gastroenterology,Children s of Nanjing Medical Department of Gastroenterology and Hepatology, Guangzhou Digestive Disease Center, Guangzhou First People s, School of Medicine, South China Department of of Gastroenterology and Hepatology, Guangzhou Digestive Disease Center, Guangzhou First People s, School of Medicine, South China of Ruiling Lu The First Affiliated of Nanchang P081 P082 P083 Machine learning model incorporating computed tomography body composition features for predicting the response to mesalamine treatment in Crohn's disease Bacillus amyloliquefaciens Combined with Resistant Starch to ameliorate Intestinal Inflammation Dendritic cells secrete S100A8 in besides neutrophils and macrophages Linlin Chen Xiangya of Central South Hailan Zhao Department of Gastroenterology and and Hepatology, Guangzhou Digestive Disease Center, Guangzhou First People s, School of Medicine, South China of Dandan Wang the Second Affiliated of Zhengzhou P084 The Effect and Immune Cell Analysis of Clostridium Butyricum on Dextran Sulphate Sodium Induced Colitis in Mice Pretreated with Antibiotic Cocktail Jing Xu Department of Gastroenterology and Hepatology, Guangzhou Digestive Disease Center, Guangzhou First People s, School of Medicine, South China of P085 The Efficacy and Gut Microbiota Analysis of Clostridium Butyricum in Dextran Sulphate Sodium Induced Colitis of Mice after Antibiotic Cocktail Pretreatment Jing Xu Department of Gastroenterology and Hepatology, Guangzhou Digestive Disease Center, Guangzhou First People s, School of Medicine, South China of P086 Astragalus polysaccharide modulates ferroptosis in a murine model of colitis and human Caco-2 cells via the NRF2/HO-1 pathway Yanjun Chen The First Affiliated of Soochow P087 Longitudinal bowel behavior assessed by bowel ultrasound in prediction of early response to anti-tnf therapy in patients with Crohn's disease: a pilot study Yujun Chen The first affiliated hospital of Sun Yat-sen P088 Identification of differentially expressed genes related to associated-colorectal cancer by bioinformatics analysis JINGYI CHEN Peking People's P089 Th17 cell-derived amphiregulin promotes colitis-associated intestinal fibrosis; through activation of mtor and MEK ; Xiaojing Zhao First Affiliated of Nanjing Medical P090 Lactobacillus rhamnosus GG Improves Sleep Deprivation Induced-Intestinal Barrier Dysfunction Xiaoqi Pang Department of Gastroenterology and Hepatology, General, Tianjin Medical, P091 MCPIP-1-mediated immunosuppression of neutrophils exacerbates acute bacteria-driven inflammation Jian Lin Center for Inflammatory Bowel Disease Research, The Shanghai Tenth People s of Tongji School of Medicine P092 Detection of A Novel Antigen for Crohn s Disease Yarong Wei Department of Gastroenterology, the First Affiliated of Anhui Medical P093 Digital Spatial Profiling Reveals Functional Shift of Enterochromaffin Cell in Patients with Ulcerative Colitis Dongping Lyu Department of Gastroenterology, Qilu, Cheeloo College of Medicine, Shandong P094 Prospective randomized controlled clinical study of mesalazine in the treatment of nonspecific terminal ileal ulcers Junrong Li Union, Tongji Medical College, Huazhong of Science and P095 Analysis between fungal microbiota and clinical phenotypes in Crohn s disease in southwest China Li Zeng Department of Gastroenterology, West China, Sichuan P096 PET/MRI for Evaluating Subclinical Inflammation of Crohn s Disease I-Lun Shih Department of Medical Imaging, National Taiwan P097 Serum interleukin-6 level in the early detection of Crohn's disease with Epstein- Barr virus infection Chunhua Jiao The First Affiliated of Nanjing Medical P098 Longer diagnosis-surgery duration is associated with an increased risk of early postoperative complications for Crohn s disease: a retrospective study Xuanyi Chen Shanghai Jiao Tong School of Medicine Affiliated Renji P099 Prealbumin and Retinol-Binding Protein 4: the Nutritional-Inflammatory Biomarkers for Identifying Endoscopic Remission in Crohn s Disease Rirong Chen The First Affiliated of Sun Yat-Sen P100 Predicting Outcomes for Crohn s disease using a molecular biomarker: PROFILE trial interim update Nurulamin Noor Cambridge s NHS Trust P101 Comparative effectiveness of second-line biological therapies for and Crohn s disease in patients with prior failure of anti-tumour necrosis factor treatment Hye Kyung Hyun Department of Gastroenterology and Institute of Gastroenterology, Yonsei College of Medicine, Yongin Severance P102 The Role of Perioperative Blood Glucose Level in Predicting Postoperative Recurrence of Crohn's Disease Chao Li The First Affiliated of Sun Yat-sen P103 Serum Interleukin 38 Levels are Associated with Disease Severity and Lesion Location in Patients with Crohn s Disease Yihan Xu Affiliated Jinling, Medical School of Nanjing P104 Peripheral blood mononuclear cell micrornas are novel biomarkers for diagnosing and monitoring Crohn s disease Hanwen Chen the Second Affiliated of Zhejiang, School of Medicine P105 NEDD8 activating enzyme inhibitor MLN4924 aggravates intestinal inflammation by inhibiting the proliferation and repairment of intestinal epithelial cells Chaohui Wang Gastroenterology Department, Sir Run Run Shaw, Zhejiang School of Medicine, P106 Faecalibacterium prausnitzii supernatant attenuates TNBS-induced colitis by regulating M2 macrophage polarization Xiaqiong Mao The first clinical medical college of Nanjing Medical P107 DCAF2 alleviates intestinal inflammation by regulating the proliferation and autophagy of intestinal epithelial cells; Yu Zhang Gastroenterology Department, Sir Run Run Shaw, Zhejiang School of Medicine P108 Effects of mitochondrial DNA on permeability of Caco-2 cells and its;mechanism Li Huihui Dept of Gastroenterology, The First Affiliated of Anhui Medical P109 Maternal diets effect the intestinal flora of offspring mice in their early life Linlin Chen Xiangya of Central South Universuty P110 UCC: A Novel Model Predicting Short-term Outcomes in Patients with Acute Severe Ulcerative Colitis Si Yu 1. Department of Gastroenterology, Peking Union Medical College, Chinese Academy of Medical Sciences & Peking Union Medical College P111 Anti-TNFα agents in preventing the postoperative recurrence of Crohn s disease: Do they still play a role in the biological era? Caiguang Liu of Sun Yat-sen P112 Measurement of stiffness of the normal terminal ileum mesentery using Shear Wave Elastography yujun chen The first affiliated hospital of Sun Yat-sen P113 The clinical value of the Nancy histological index in assessing the activity degree of disease JIA Zhe Affiliated of Hebei P114 Study on the Efficacy and Safety of Fecal Microbiota Transplantation Combined with Biologics in the Treatment of Inflammatory Bowel Disease Di Zhao Department of Colorectal Disease, Shanghai Tenth People s, Tongji School of Medicine P115 Study on The Correlation Between GSTP1 Gene Polymorphism and Inflammatory Bowel Disease in Guangxi Zhuang Population and Han Population Yan Chen Guangxi P116 Phellodendrine promotes autophagy by regulating the AMPK/mTOR pathway and treats Weilong Zhong Tianjin Medical General P117 Autotaxin (ATX) inhibited autophagy through mtor pathway and destroyed intestinal epithelial barrier in colitis Wenjie Shi Dep.Gastroenterology, Tongji, Tongji Medical College, Huazhong of Science &

P118 A new pathway ameliorating post-traumatic stress disorder : focus on roseburia intestinalis and the gut-brain axis. fenghua xu Department of Gastroenterology, Army Medical Center of PLA affiliated with Army Medical P119 Oral beclomethasone dipropionate as an add-on therapy and response prediction in Korean patients with Kyuwon Kim Department of Gastroenterology, of Ulsan College of Medicine, Asan Medical Center, Korea P120 Association between early vedolizumab trough levels and biochemical remission in patients with Crohn's disease Kyuwon Kim Department of Gastroenterology, of Ulsan College of Medicine, Asan Medical Center, Korea P121 Application of a clinical decision support tool for predicting biochemical remission with vedolizumab therapy in patients with Kyuwon Kim Department of Gastroenterology, of Ulsan College of Medicine, Asan Medical Center, Korea P122 Ustekinumab improves health-related quality of life in patients with moderate-tosevere Crohn s disease: results up to Week-48 of the STARDUST trial Silvio Danese IBD Center, Humanitas, Milan, Italy P123 The impact of exclusive enteral nutrition on the gut microbiome and bile acid metabolism in pediatric Crohn s disease Yao Lv Children s, Zhejiang School of Medicine P124 Maintenance of clinically meaningful improvement in health-related quality of life in moderate-to-severe Crohn s disease, ustekinumab-treated patients: IM-UNITI long-term extension study William J. Sandborn of California San Diego, La Jolla, CA, USA P125 BAFF Blockade Attenuates Inflammatory Responses and Inhibits NLRP3 inflammasome in DSS-induced colitis ying zhang Union, Tongji Medical College, Huazhong of Science and P126 The prevalence of concomitant small bowel lesions in Crohn's disease and their effects on reoperation in patients undergoing ileocolic resection Wenwei Qian General Of Eastern Theater Command P127 Long-term outcomes of Crohn s disease patients with transmural structural bowel damage: Results from a single center study Wenwei Qian General Of Eastern Theater Command P128 P129 P130 Microbiota Metabolite Butyrate Differentially Regulates Th1 and;th17 Cells Differentiation and Function in Induction of Colitis Randomized controlled trial: perioperative dexamethasone reduces excessive postoperative inflammatory response and ileus after surgery for inflammatory bowel disease Effect of guselkumab induction therapy on inflammatory biomarkers in moderately-to-severely active Crohn s disease patients: Week 12 results from GALAXI-1 Study Liang Chen Department of Gastroenterology, The Shanghai Tenth People s, Tongji, Shanghai, China Tenghui Zhang Jinling Bruce Sands Icahn School of Medicine at Mount Sinai P131 Elevated Levels of IL-27 are Associated with Disease Activity in Patients with Crohn s Disease Xiufang Cui Department of Gastroenterology, First Affiliated of Nanjing Medical P132 Appendiceal orifice inflammation is associated with lower rate of mucosal healing in patients with Chang Kyo Oh The Catholic of Korea Seoul St. Mary P133 Computed Tomography Enterography Findings Correlate with Histological Changes and Predict the Requirement of Surgical Intervention in Stenosing Crohn s Disease Ming Duan Department of General Surgery, Jinling, Nanjing Medical P134 Analysis on clinical and endoscopic features of patients with - associated colorectal neoplasia Wenyu Jiang First Affiliated of Nanjing Medical P135 Clinical differences between elderly-onset and non-elderly-onset Fangmei Ling Division of Gastroenterology,Union,Tongji Medical College,Huazhong of Science and P136 Stigma and self-efficacy among Inflammatory Bowel Diseases patients with stoma in China: cross-sectional web-based survey study Yuting Wang the Second Affiliated of Zhejiang P137 A Sequential Study of Follow-up Questionnaires on the Impact of the Coronavirus Disease 2019 Pandemic on Patients with Inflammatory Bowel Disease in Hubei Province, China Meiping Yu Department of Gastroenterology, Tongji, Tongji P138 P139 Increased Clinical Remission in Patients with Crohn's Disease Receiving Proactive Monitoring of Infliximab Trough Concentration Compared with Reactive Monitoring Association of Magnetic-Guided Capsule Endoscopy, Magnetic Resonance Enterography findings and Pediatric Crohn s Disease Activity Index for pediatric patients with Crohn s disease Yue Zhang Jia Li Department of Gastroenterology, First Affiliated of Nanjing Medical, Nanjing, China Department of Paediatrics, Ruijin, Shanghai Jiao Tong School of Medicine P140 Furin inhibits epithelial cell injury and alleviates experimental colitis by activating the Nrf2-Gpx4 signaling pathway Shouquan Dong ZhongNan of Wuhan P141 Identification of microrna-16-5p and microrna-21-5p in feces as potential noninvasive biomarkers for inflammatory bowel disease Rui Zhou Zhongnan of Wuhan P142 Carboxypeptidase A6 was identified and validated as a novel potential biomarker for predicting the occurrence of active Haizhou Wang Zhongnan hospital of Wuhan P143 Risk factors and characteristics associated with nonalcoholic fatty liver disease in patients with ischemic colitis Xixian Zhao Zhongnan hospital of Wuhan univerity P144 Primary extrasensal nasal-type natural killer/t-cell lymphoma of the sigmoid colon and ileocecal junction: a case report Chang Gao Zhongnan of Wuhan P145 Preliminary clinical analysis of argon ion coagulation and submucosal drug injection in the treatment of radioactive enteritis Guanlin Lu 武汉大学中南医院 P146 Clinical Analysis of Extraintestinal Manifestations in 122 Patients with Ulcerative Coliti Guanghui Ren the second affiliated of Dalian Medical P147 Group2 innate lymphoid cells are down-regulated in intestinal inflammation Emi Irie Keio P148 A high-salt diet protects interleukin 10-deficient mice against chronic colitis through improving the mucosal epithelial barrier Dezhi Wang Department of Gastroenterology, Seventh Medical Center of Chinese PLA General P149 Clinical characteristics and outcomes in ustekinumab-treated adults in the UNITI studies by age at Crohn s disease onset Stanley Cohen Children s Center for Digestive Health, Atlanta P150 Histologic Features Predicting Prognosis And Their Relationship With Endoscopic Findings In Ulcerative Colitis Patients With Mucosal Healing Kisung Kim Chung-Ang College of Medicine, Department of Internal Medicine P151 Clinical efficacy of fecal microbiota transplantation for patients with small intestinal bacterial overgrowth-a randomized, placebo-controlled trial study Lu Chen Department of Gastroenterology, Army Medical Center of PLA affiliated with Army Medical P152 Inflammatory Bowel Disease Intelligent Identification Based on Deep Learning Using Colonoscopy Images Guangcong Ruan Department of Gastroenterology, Army Medical Center of PLA affiliated with Army Medical P153 Inflammatory Bowel Disease Intelligent Identification Based on Deep Learning Using Colonoscopy Images Guangcong Ruan Department of Gastroenterology, Army Medical Center of PLA affiliated with Army Medical P154 Free antibody-to-infliximab is a superior biomarker for predicting clinical outcomes in Crohn s disease than total antibody-to-infliximab Eun Sil Kim Samsung Medical Center P155 Efficacy of Faecal Microbiota Transplantation in Patients with Parkinson's Disease: A Randomized, Single-blind, Placebo-controlled Study Yi Cheng Department of Gastroenterology, Army Medical Center of PLA affiliated with Army Medical P156 The effect of PAI-1 on endoplasmic reticulum stress related signal pathway in rat model with inflammatory bowel disease Zhang Lei Xiaoshan First People s P157 The pharmacokinetics and immunogenicity of 5 years of treatment with ustekinumab (UST): Results from the IM-UNITI long-term extension (LTE) Omoniyi J. Adedokun Janssen Research & Development, LLC P158 The clinical efficacy of five-flavor sophora flavescens enteric-coated capsules combined with mesalazine in the treatment of ; XIAOJING QUAN 1Department of Gastroenterology, Second Affiliated of Xi'an Jiaotong P159 Clinical Study on the Relationship Between Serum Homocysteine and Ulcerative Colitis Kaicheng Xie the second affiliated of Dalian Medical P160 MyD88 inhibition-induced intestinal microbial imbalance stimulates inflammatory response via NOD-like receptor signaling pathway Yu Chen Department of Gastroenterology, Tongji of Tongji P161 Comparative study of mucus volume in patients with Yu Kamitani Tottori P162 Study on reliability and validity of Chinese version of inflammatory bowel disease disability index Han Xu the Second Affiliated of Soochow

P163 Calprotectin and lactoferrin could be sensitive and specific markers for early IBD screening in high-risk population Guang-Yao Wu Dongguan Kanghua P164 A Convolutional Neural Network-Based Endoscopic Images Diagnosis System Classifying Crohn s Disease and Ulcerative Colitis Lijia Wang Department of Gastroenterology, Tongji, Tongji P165 Crohn s disease after rituximab therapy: a case report Shuai Huang the First of Jilin P166 Identification of efficacy predictive genes long-term responding to anti-α4β7 integrins in patients Yonghao Chen Department of Gastroenterology, the First Affiliated of Anhui Medical P167 Mitochondrial fission is involved in the early inflammation of UC Shichen Fu Qilu of Shandong P168 Analysis of Real World Data after Use of the Herbal Medicine "Indigo Naturalis" in Patients with Ulcerative Colitis Fumie Shimada Keio P169 Microbiota metabolite butyrate constrains neutrophil functions and ameliorates mucosal inflammation in inflammatory bowel disease Gengfeng Li Shanghai tenth people's hospital, Tongji School of Medicine P170 Infliximab Biosimilar CT-P13 Observational Studies for Rheumatoid Arthritis, Inflammatory Bowel Diseases, and Ankylosing Spondylitis: Analysis of Long-Term Safety and Effectiveness JaeHee Cheon Yonsei Colleage of Medicine P171 Pericentriolar material 1 promotes inflammation in via activating NLRP3/gasdermin D-mediated pyroptosis Yunling Wen of Kunming Medical P172 Clostridium butyricum activates JAK2/STAT3 signaling pathway through IL-10 to improve Shuchun Wei Department of Gastroenterology, Renmin of Wuhan P173 Clinical study on the expression of Piezo1 in small intestinal mucosa of 57 patients with Crohn's disease Lixue Chen the first affiliated hospital of anhui medical university P174 P175 Analysis of clinical features associated with favourable outcomes from ustekinumab treat-to-target strategy in Crohn s disease patients in the STARDUST trial Patient-reported outcomes (PROs) of response and remission following guselkumab induction treatment: Results through week-12 of the phase-2 GALAXI-1 study Silvio Danese IBD Center, Humanitas Julian Panes Clínic de Barcelona, IDIBAPS, CIBERehd, P176 Risk Factors of Bone Loss in Ulcerative Colitis Patients and its Relationship with Fecal Microbiota Li Yingchao of Xi 'an Jiaotong P177 The relationship of histological remission with the duration of the anamnesis;.; Oleg Knyazev Moscow Scientific Center named after A. S. Loginov P178 Dose Adjustment in Moderate to Severe Ulcerative Colitis: Results from Year 3 UNIFI Maintenance Study Long-term Extension David S. Rowbotham Auckland City P179 Study on the role of ATX/LPA axis in mucus barrier in colitis murine Wenjie Shi The First Affiliated Of Nanchang P180 MiR-204-5p regulates macrophage-mediated inflammatory response in ulcerative colitis Bing Li Department of Gastroenterology, Qilu of Shandong P181 Risk of Gastric Cancer and Associated Factors in Newly Diagnosed Ulcerative Colitis Soon Chang Park Department of Internal Medicine, Yonsei Wonju College of Medicine P182 Inositol-Requiring Kinase 1 Regulates Apoptosis via Inducing Endoplasmic Reticulum Stress in Colitis Epithelial Cells Zhang Bei the 2nd affiliated of NanChang P183 Clinical value of neutrophil monocyte lymphocyte ratio in diagnosing ulcerative colitis and its disease severity Deng Beiying Renmin of Wuhan P184 Differentiating Crohn s Disease from Intestinal Tuberculosis by Fusion; Correlation Neural Network Yani Yin Xiangya hospital,csu P185 Early PRO-2 symptom remission following guselkumab induction treatment: results through week 12 of the phase 2 GALAXI 1 study Walter Reinisch Medical of Vienna P186 Deletion of IL-6 Exacerbates Colitis and Induces Systemic Inflammation in IL-10- Deficient Mice Mei Ye Zhongnan of Wuahan P187 Regulation of IL12B expression in human macrophages by TALEN-mediated epigenome editing Meng Chen Zhongnan of Wuhan P188 Analysis of the clinical efficacy of infliximab in the treatment of steroid-refractory in children Ying Chen shengjing hospital of China Medical P189 STAT1 epigenetically regulates LCP2 and TNFAIP2 by recruiting EP300 to contribute to the pathogenesis of inflammatory bowel disease Yali Yu Zhongnan of Wuhan P190 Intestinal Ultrasound in Evaluating Disease Location, Activity, and Stenosis of Crohn's Disease Chenjing Xu The First Affiliated of Nanjing Medical P191 Association between NOD2/CARD15 gene polymorphisms and Crohn's disease in Chinese Zhuang patients Xiaoping Lv of Guangxi Medical P192 IL-21 and Bcl-6 regulate the proliferation and secretion of Tfh and Tfr cells in the intestinal germinal center of patients with inflammatory bowel disease Xiaoping Lv IL-21 and Bcl-6 regulate the proliferation and secretion of Tfh and Tfr cells in the intestinal germinal center of patients with inflammatory bowel disease P193 Intestinal ultrasound predicts disease behavior progression in patients with Crohn's disease: a single-center, retrospective study Jinshen He of Sun Yat-sen P194 Safety of ustekinumab across approved adult indications in Crohn s disease,, psoriasis, and psoriatic arthritis through up to 5-Years Silvio Danese Professor of Gastroenterology, Humanitas and Director, IBD Center, Humanitas Research P195 Cholecystectomy-induce secondary bile acid accumulation ameliorates experimental colitis in mice Yun Liu Department of Gastroenterology, Peking People s P196 Study on the correlation between Endoscopic appearance of UC with clinical and histological and analysis of its predictive effect on endoscopic mucosal healing Xiafei Chen Nanjing Gulou P197 Short-chain fatty acids improve intestinal epithelial barrier by regulating the expression of Slc26a3 Kaixin Peng Department of Gastroenterology, Tongji of Tongji P198 Observation on the curative effect of infliximab in treating patients with Perianal fistulizing Crohn s disease Ruoyi Zhang The first affiliated hospital of sun yat-sen university P199 Patients with inflammatory bowel disease and post-inflammatory polyps have an increased risk of colorectal neoplasia: a meta-analysis Jialing Shi The First Affiliated of Guangxi Medical P200 SLC26A3(DRA) Ameliorates Dextran Sulfate Sodium-Induced Ulcerative Colitis in Mice by Regulating Homeostasis of Gut Microbiota Suhong Xia Huazhong of Science and P201 Study on the consistency of cytomegalovirus detection between immunohistochemistry and real-time fluorescent quantitative PCR in intestinal mucosal biopsy specimens guanglan wang Sir Run Run Shaw, School of Medicine, Zhejiang P202 A Broad m6a Modification Landscape in Inflammatory Bowel Disease Kai Nie The Department of Gastroenterology In The Third Xiangya of Central South P203 Dietary Inflammatory Potential associated with disease activity in patients with Crohn s disease Zhenyi Tian Department of Gastroenterology. The First Affiliated of Sun Yat-sen P204 A convolutional neural network-based endoscopic images diagnosis system classifying Crohn s Disease and Ulcerative Colitis Liping Chen Department of Gastroenterology, Tongji, Tongji P205 Anti-inflammatory effect and mechanisms of Hongyuyin Formula on inflammatory bowel disease model via IL-6/JAK2/STAT3 signal pathway XINXIN ZHANG Longhua of Shanghai of Traditional Chinese Medicine P206 Ustekinumab safety in older patients with IBD (Crohn s disease + ulcerative colitis) and across all indications: Data from pooled analysis Subrata Ghosh Institute of Translational Medicine, NIHR Biomedical Research Centre, of Birmingham P207 EXTRACELLULAR MATRIX, MILK FAT GLOBULE EPIDERMAL GROWTH FACTOR 8, EXERTS ANTI-FIBROTIC EFFECTS IN CROHN'S DISEASE RELATED-INTESTINAL FIBROSIS Si-Nan Lin Department of Gastroenterology and Hepatology, The First Affiliated of Sun Yat-sen

P208 Therapeutic effect of appendectomy on dextran sodium sulfate-induced chronic colitis in mice Yu Zhang Department of Gastroenterology, Peking People's P209 Effects of FUT2 loss-of-function mutation on the pathogenesis of inflammatory bowel diseases Sijing Cheng Guangdong Institute of Gastroenterology, Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, the Sixth Affiliated, Sun Yat-sen P210 Surgical treatment of Crohn's disease with intestinal stenosis Yangbo Li Wuhan People's P211 Charlson Comorbidity Index Predicts Colonic Diverticular Rebleeding Dong Hyun Kim Chonnam National P212 Awareness and cognition of illness in patients with inflammatory bowel disease: A multicenter survey in China Kaichun Wu Department of Gastroenterology, Xijing, Fourth Military Medical, P213 Perception Gap between Patients with Inflammatory Bowel Disease (IBD) and Healthcare professionals in China: A Cross-sectional Study Kaichun Wu Department of Gastroenterology, Xijing, Fourth Military Medical, P214 Bowel First is a safe and feasible surgical approach for Crohn s disease patients with complex internal fistulas Wei Liu Department of IBD Center, Sir Run Run Shaw, School of Medicine, Zhejiang P215 Real-world short-term effectiveness of ustekinumab in Crohn s disease: Results from a multi-center prospective study in China Qian Cao Department of Gastroenterology, Sir Run Run Shaw, College of Medicine Zhejiang, P216 Colon-related fistula is associated with a worse outcome in Crohn s disease Wei Liu Department of IBD Center, Sir Run Run Shaw, School of Medicine, Zhejiang P217 Crohn s Disease-associated Adherent-Invasive Escherichia coli is Associated with Severe Gut Mucosal Dysbiosis Zhilu XU Department of Medicine and Therapeutics, Institute of Digestive Disease, State Key Laboratory of Digestive Diseases, LKS Institute of Health Science, The Chinese of Hong Kong P218 Lipoprotein: A New Serum Biomarker of Inflammatory Bowel Disease Activity Xi Zhao Division of Gastroenterology, Union, Tongji Medical College, Huazhong of Science and P219 The application of stapled strictureplasty in Crohn s disease Wei Liu Department of IBD Center, Sir Run Run Shaw, School of Medicine, Zhejiang P220 Strictureplasty may gain more preference in the surgical management in Cohn s disease: a case-matched study Wei Liu Department of IBD Center, Sir Run Run Shaw, School of Medicine, Zhejiang P221 Inhibition of JAK1 signaling by a novel selective JAK1 inhibitor protects against intestinal mucosal inflammation by inhibiting STAT3 phosphorylation and regulating CD4+ T cells activation Yanting Shi Department of Gastroenterology, Xijing, Fourth Military Medical, P222 Corticosteroid-sparing effects of ustekinumab therapy for (UC) through 3 years: UNIFI long-term extension Ellen J. Scherl Weill Cornell Medicine, New York, P223 Enhanced immune-modulatory effects of thalidomide and azathioprine cotreatment on human T cell Tong LI First affiliated hospital of Sun Yat-sen university P224 Histological remission better predicts corticosteroid use, hospitalization and treatment escalation over 3 years of follow-up Tong LI First affiliated hospital of Sun Yat-sen university P225 Preoperative endoscopic activity predicts the occurrence of pouchitis after ileal pouch anal anastomosis in : A multicenter retrospective study in China Weimin Xu Department of Colorectal Surgery, Xinhua, Shanghai Jiaotong School of Medicine, Shanghai 200092, China P226 Implications of an specific ileocecal ulcer Mi Chen Gastroenterology Department in The first Affiliated of Xi'an Jiaotong P227 Changes of medical treatment in inflammatory bowel disease: a single center study in 2010-2019 in China He Zhou State key Laboratory of Cancer Biology, National Clinical Research Center for Digestive Diseases and Xijing of Digestive Diseases, Air Force Military Medical P228 Serum LRG as a novel biomarker to monitor Crohn's disease activity. Yoshiaki Takada Internal Medicine, Keio School of Medicine P229 Vitamin D receptor-dependent protective effect of moderate hypoxia in a mouse colitis model Zheng Wang Department of Gastroenterology, PUMC, CAMS and PUMC, P230 Simple assessment of colon wall thickening is useful to predict endoscopic disease activity in patients with Natsuki Sumiyoshi Medicine, The Jikei P231 Efficacy and safety of Adalimumab in the treatment of Crohn's disease Tian Pu of Zhengzhou P232 Distinct MiRNAs in the Intestine of Stricturing and Penetrating Crohn Disease Patients Feilong Guo Department of General Surgery, Jinling, School of Medicine, Nanjing P233 Prior anti-tnf-alpha exposure is associated with reduced tofacitinib efficacy in patients with Yudai Hasegawa Medicine, The Jikei P234 Schaumann Bodies in Crohn s Disease: a pathologic feature may serve as a clue for differential diagnosis. Xinning Liu Department of Pathology, The First Affiliated, Sun Yat-sen, Guangzhou, China. P235 Tertiary Lymphoid Organs were correlated with intestinal fibrosis in Crohn s Disease: from a pathologic aspect. Xinning Liu Department of Pathology, The First Affiliated, Sun Yat-sen, Guangzhou, China. P236 The Correlation of Gene Polymorphisms and Leukopenia Induced by Azathioprine in Inflammatory Bowel Disease in China YANYAN WANG the First Affiliated of Anhui Medical P237 Ustekinumab is effective for UC with stenosis: a case report Ailing Liu Department of Gastroenterology, the Affiliated of Qingdao P238 Predicting risk factors of steroid dependence after initial steroid therapy in Yusuke Miyatani Center for Advanced IBD Research and Treatment, Kitasato Kitasato Institute P239 Discrimination between Chronic active Epstein-Barr Virus-associated enteritis and inflammatory bowel disease: a multi-center retrospective study. Jing Li West China of Sichuan P240 Changes of intestinal microecology in patients with Crohn's disease treated with infliximab Yuyang Chen Department of Gastroenterology, Xin qiao,army Medical P241 The experiences and support needs of Crohn's patients living with home nutritional support in China: a qualitative interview study Zehua Zhao Jinling, Medical School of Nanjing P242 Correlation of serum bile acid profile and inflammatory activity in patients with Crohn s disease Rui Sun School of Medicine, Southeast P243 Leucine-rich repeat C19 depletion alleviates intestinal mucus barrier disruption of offspring exposed to maternal high fat diet Mengfan Li Tianjin Medical General P244 The role and mechanism of mir-21 regulating PTEN in the occurrence of CD Zhizhi Wang The First Affiliated of Nanchang P245 Dysregulated circadian rhythm in mice colon: NR1D1 suppression deteriorates DSS-induced colitis via the TNF signaling pathway Yidong Chen Division of Gastroenterology, Union, Tongji Medical College, Huazhong of Science and P246 Comparison of the pharmacokinetics of CT-P13 between Crohn s disease and Eun Soo Kim Kyungpook National P247 Clinical Evaluation of Vagus Function, Psychological Status and Quality of Life in Patients with Inflammatory Bowel Disease and Analysis of Related Risk Factors Jingjing Ma Department of Gastroenterology, the First Affiliated of Nanjing Medical P248 Mucosal Profiling of Pediatric-Onset Colitis and IBD Reveals Common Pathogenics and Therapeutic Pathways Bing Huang Guangzhou Institute of Pediatrics, Guangzhou Women P249 Observation on the therapeutic effect of Kuijie enema II on by regulating antibacterial peptide to inhibit inflammatory reaction Cheng yile Nanjing of Chinese Medicine affiliated to Nanjing of Chinese Medicine P250 Predictors of perianal fistula recurrence following perianal surgical intervention in Crohn s disease Feihong Deng The Second Xiangya of Central South P251 Predictors of perianal fistula recurrence following perianal surgical intervention in Crohn s disease Feihong Deng The Second Xiangya of Central South

P252 Efficacy and safety of oral sulfate tablet for the bowel preparation in patients with inflammatory bowel disease: comparison with 2L polyethylene glycol with ascorbic acid Kyeong Ok Kim Yeungnam College of Medicine P253 The depletion of psoas muscle mass as an indicator of activity in Crohn's disease Yan Li Department of Gastroenterology, Zhongnan of Wuhan P254 GAS6 from CD200+ adipose-derived stem cells mitigates colonic inflammation via a macrophage-dependent manner Xian-rui Wu The Sixth Affiliated, Sun Yat-sen P255 Differential Diagnosis Between Ileum Crohn's Disease And Cryptogenic Multifocal Ulcerous Stenosing Enteropathy Tianyu Zhang Department of Gastroenterology, Shanghai Ruijin P256 Clinical response of vedolizumab at week 6 predicted endoscopic remission at week 24 in Daisuke Saito Department of Gastroenterology and Hepatology, Kyorin School of Medicine P257 Characteristics of electrogastrography and electroenterogram in patients with Crohn's disease Ying Xu the First Affiliated of Nanjing Medical P258 Effects of psychosocial function in pediatric with inflammation bowel disease during COVID-19 pandemic Huihui Zhang Children's of Chongqing Medical P259 L6H21 stabilizing gut barrier improves EtOH-LPS-induced hepatic steatosis and injury in mice Ren Li The first affilicated hospital of xi'an jiaotong university P260 A Feasible Animal Model for Aspirin-associated Enteropathy Mingyu Zhang Department of Gastroenterology, Tongji, Tongji P261 Defining Microbe-Metabolite Indicators Associated with Fecal Microbiota Transplantation Efficacy in Inflammatory Bowel Disease Di Zhao Department of Colorectal Disease, Shanghai Tenth People s, Tongji School of Medicine P262 Study on the mechanism of MMP7/MMP9 participating in with anxiety and depression Qiongyu Li Binzhou Medical P263 Value of Fibrinogen as Predictor Markers of Disease Activity in UC Patients jiaming Hu Renmin of Wuhan P264 Wumei Decoction Ameliorates Intestinal Mucosal Inflammation by Inhibiting Th1/Th17 Cell Differentiation and Maintaining Microbial Homeostasis Xiaohan Wu Center for IBD Research, Department of Gastroenterology, The Shanghai Tenth People s of Tongji P265 Identification of pharmacological autophagy regulators of active Peishan Qiu Zhongnan of Wuhan P266 Massive bleeding of a vascular malformation of the small intestine in imaging negative Crohn's disease: a case report Jiajia Li Department of Gastroenterology, the Affiliated of Yangzhou P267 Antibiotic-Modulated Microbiota Suppresses Colon Inflammation in Mice by Modulating the Intestinal Bile Acids Metabolism Zhenghao Ye Department of Gastroenterology, Tongji, Huazhong of Science and P268 Effects of platelet microparticles on intestinal permeability in inflammatory bowel disease Bin Yang the First affiliated hospital of Anhui Medical P269 New-onset tuberculosis in previously T-SPOT.TB-negative patients with Crohn's disease receiving anti-tnf-α therapy in a tuberculosis-endemic region Yue Yu ZheJiang School of Medicine Second Affiliated P270 A Interleukin-10 receptor (IL10R) deficiency patient in long time clinical remission without Hematopoietic stem cell transplantation Zhang Xiaoqing Children's of Soochow P271 Semi-elemental versus polymeric exclusive enteral nutrition in the preoperative optimization for patients with Crohn s disease: a randomized controlled trial Xiaolong Ge Sir Run Run Shaw, School of Medicine, Zhejiang P272 Analysis of multidisciplinary treatment mode in type 2 intestinal failure Xiaolong Ge Sir Run Run Shaw, School of Medicine, Zhejiang P273 Clinical characteristics of severe complicated with cytomegalovirus infection Sumei Sha The Second Affiliated of Xi'an Jiaotong P274 Treatment of steroid-dependent rectal sparing associated with severe autoimmune hemolytic anemia with oral mycophenolate mofetil--a case report and review of literature Sumei Sha The Second Affiliated of Xi'an Jiaotong P275 Ustekinumab Intravenous (IV) Optimization in severe Crohn s Disease haixia ren Renmin hospital of WuHan university P276 Urine raman spectroscopy as a novel valuable tool for characterization and noninvasive diagnosis of Crohn s disease Yaling Wu Shanghai Tenth People s, Tongji School of Medicine P277 Bowel Ultrasound Enhance the Predicting Value Based on Clinical Indicators: A Scoring System for Moderate to Severe Endoscopic activities in Patients with Ulcerative Colitis Mengmeng Zhang Peking Union Medical College, Chinese Academy of Medical Sciences and Peking Union Medical College P278 Altered regional homogeneity and topological network in patients with Ulcerative Colitis Fenrong Chen Department of Gastroenterology, Second Affiliated of Xi an Jiaotong P279 Quality of Working Life and Influencing Factors for Patients with Inflammatory Bowel Disease in China: Results from A National Web-Based Survey Song Xu Department of Gastroenterology, Second Affiliated of Zhejiang School of Medicine P280 Moderate to severe elderly patients with are more likely to have treatment failure and adverse outcome Mengmeng Zhang Peking Union Medical College, Chinese Academy of Medical Sciences and Peking Union Medical College P281 Application of capsule endoscopy in the diagnosis of Crohn's disease Chen Lin Renmin of Wuhan P282 The role of cytomegalovirus colitis on short- and long-term outcomes for patients with Mengmeng Zhang Peking Union Medical College, Chinese Academy of Medical Sciences and Peking Union Medical College P283 Tongue coating microbiota as a novel non-invasive biomarker in Lei Zhu Jiangsu Province of Traditional Chinese Medicine P284 Optimization of Preoperative Management in Patients with Penetrating Crohn s Disease: a Pilot Study of Cocktail Strategy Siming Sui First Affiliated of Sun YatSen P285 The role of mechanosensitive ion channel Piezo1 in inflammatory bowel disease Qiuyuan Liu the First affiliated hospital of Anhui Medical P286 The mechanism of sacral nerve stimulation inhibiting macrophage activation through acetylcholine to improve inflammatory bowel disease Yan Meng Division of Gastroenterology and Hepatology, Johns Hopkins School of Medicine, Baltimore, MD P287 Microbial Metabolite Trimethylamine-N-Oxide Induces Intestinal Carcinogenesis through Inhibiting Farnesoid X Receptor Signaling Wanru Zhang Tianjin Medical General P288 The role of Pelvic MRI-Based Score in Assessing the Severity and Follow-up of Patients With Crohn s Perianal Fistulas Wei Juan Jinling hospital P289 Gene expression profiling in identifies characteristics for anti-tnf response and targets for alternative therapies Marietta Iacucci of Birmingham P290 Unchanging Better than Progression: A Long-term Disease Behavior and Surgical Intervention Cohort Analysis in ized Patients with Crohn's Disease Xiaoyin Bai Peking Union Medical College P291 Current status of key quality indicators for inflammatory bowel disease in China: A questionnaire survey of tertiary hospitals Xiaoyin Bai Peking Union Medical College P292 Fibrotic of Colonic Wall in Patients with Ulcerative Colitis underwent a colectomy Feng Xiaoyue Department of Gastroenterology and Hepatology of Jinling P293 inflammatory fibroid polyp in crohn's disease: a rare case of intussusception Qiong Jiang Jinling P294 Long-term Prognosis of Crohn s Disease Patients with Enterovesical Fistula: Experience from a Tertiary Medical Center Runfeng Zhang Department of Gastroenterology, Chinese Academy of Medical Sciences & Peking Union Medical College P295 Whether intranasal drip of oxytocin ameliorates abnormal stress behavior in mice with colitis Biying Jin Department of Gastroenterology, Qilu, Cheloo College of Medicine P296 THE THERAPEUTIC EFFECT AND RELATED MECHANISM OF LACTIC ACID ON ULVERATIVE COLITIS BY REGULATING PYROPTOSIS Siyuan Sun Tianjin Medical Univerisity General

P297 Long-term follow-up in children with Crohns disease after exclusive enteral nutrition induction therapy youyou luo Children's hospital, school of medicine P298 Construction of prognosis model for gastric cancer liver metastasis Ting Wang Renmin of Wuhan P299 The function and mechanism of long non-coding RNA TNFRSF10A-AS1 in colorectal cancer; Dandan Wang The Second of Hebei Medical P300 Association Between Helicobacter Pylori Infection and Ulcerative Colitis: A Meta- Analysis Study Alesia Mauna Faculty of Medicine, Universitas Indonesia P301 Usefulness of colestimide for postoperative refractory diarrhea in patients with Crohn's disease Aya Hojo Center for Advanced IBD Research and Treatment, Kitasato Kitasato Institute P302 The Effect of TL1A on Th22 Differentiation and IL-22 Expression in Chronic Experimental Colitis Mice Chenyang Li The Second of Hebei Medical P303 Temporal changes in treatment paradigm and long-term prognosis of Crohn's disease: a population-based cohort study in China Lingya Yao Sir Run Run Shaw, College of Medicine Zhejiang P304 Melatonin Mitigates Oxazolone-induce Colitis in Microbiota-dependent Manner Zixiao Zhao Qilu hospital of Shandong university P305 Discrimination between colorectal tumors, and normal controls with mucosal gut microbiota by machine learning in metagenome dataset Namjoo Kim Department of Gastroenterology, Korea Guro, P306 The efficacy and safety of anti-tnf agents in the treatment of Intestinal Behcet s disease, a systematic review and meta-analysis Mengyuan Zhang Department of Gastroenterology, Peking Union Medical College P307 Triptolide alleviates experimental colitis in mice by inhibiting the polarization of M1 macrophages and regulating NLRP3 inflammasome and Nrf2/HO-1 signaling pathway Huining Fan Shanghai Jiao Tong Affiliated Sixth People s P308 The expression of IL-26 in inflammatory bowel disease and its regulatory effect on macrophage Dongjuan Song Division of Gastroenterology and Hepatology, Key Laboratory of Gastroenterology and Hepatology, Ministry of Health, Inflammatory Bowel Disease Research Center, Renji, School of Medicine, Shanghai Jiao Tong, Shanghai Institute of Digestive Disease P309 Exclusive Enteral Nutrition resolves ileocolonic inflammation in adults with Crohn s disease through regulating neutrophils and monocytes immune response Na Diao Sun Yat-sen P310 Hypermethylation of mir-145 promoter-mediated SOX9-CLDN8 pathway regulates intestinal mucosal barrier in Crohn s Disease Xiaojun Zhuang of Sun Yat-sen P311 The Impact of Co-existing Depression and Anxiety on Outcomes in Inflammatory Bowel Diseases : A Nationwide Population-Based Study Seulji Kim Seoul National College of Medicine P312 Stringent screening strategy leads to significant risk reduction of tuberculosis in patients with inflammatory bowel disease receiving anti-tnf therapy: A real world cohort analysis from a TB endemic region Peeyush Kumar All India institute of medical sciences P313 Clinical study on the expression of FUT2 and FUT3 in the intestinal mucosa of patients with inflammatory bowel disease Xin Chen Affiliated of Hangzhou Normal P314 P315 A shortened diagnostic interval and its associated clinical factors and related outcomes in inflammatory bowel disease patients from a cohort study in China Caspase-1/11 deletion aggravates experimental intestinal fibrosis by ameliorating pyroptosis Runing Zhou Runing Zhou Department of Gastroenterology, Peking Union Medical College, Chinese Academy Medical Sciences and Peking Union Medical College Department of General Surgery, Peking Union Medical College, Chinese Academy Medical Sciences and Peking Union Medical College P316 Prevalence and Predictors of Non-alcoholic Liver Disease on MRI among Patients with Crohn's Disease: A Retrospective Cohort Study Qijin Hong Shanghai Renji P317 Development and validation of two new score models for disease activity evaluation of patients with Crohn s Disease based on bowel ultrasound and other biomarkers Qingyang Zhou Peking Union Medical College, Peking Union Medical College and Chinese Academy of Medical Sciences P318 The revision of donor screening of fecal microbiota transplantation for treatment of patients with Xiaochen Zhang Department of Gastroenterology, Juntendo School of Medicine P319 Small Intestinal Bacterial Overgrowth, A Predictor of Clinical Relapse in Patients with quiescent Crohn's Disease Jing Feng Department of Gastroenterology and Hepatology, Jinling, the First School of Clinical Medicine, Southern Medical P320 Expression of Cx43 in patients with Weidong Liu People s of Xinjiang Uygur Autonomous Region P321 Analysis of nutritional status and risk factors of patients with Crohn's disease Huiling Liao Wuhan P322 Risk factors for and impact of delayed infliximab treatment among patients with Crohn's disease during the COVID-19 epidemic in China: a propensity scorematched analysis Yong Li Department of Gastroenterology, Xiangya, Central South P323 Dose the GLIM criteria represent more appropriate for nutritional assessment in patients with Crohn's disease? Yong Li Department of Gastroenterology, Xiangya, Central South P324 Proper diets might reduce the risk of inflammatory bowel disease: a propensity matching analysis of multicenter study in China Xuanfu Chen Peking Union Medical College, Peking Union Medical College, Chinese Academy of Medical Sciences P325 Bioelectrical impedance phase angle: a non-invasive index to monitor the disease activity of male patients with Crohn's disease Ziheng Peng Department of Gastroenterology, Xiangya, Central South P326 Activation of platelet NLRP3 inflammasomes in Crohn's disease SI Zhang Fudan P327 Edema index as a more sensitive indicator of nutritional status with Crohn s disease Duo Xu Department of Gastroenterology, Xiangya, Central South P328 Regulatory T cell-derived exosomes regulate the repair of intestinal epithelial barrier damage in inflammatory bowel disease by transmitting mir-195a-3p Fei Liao WuHan P329 Corticotropin releasing hormone promotes inflammatory bowel disease via inducing intestinal macrophage autophagy Jiayi Wu The first affiliated hospital of Navy Military P330 Dietary Xylo-oligosaccharide Ameliorates Colonic Mucus Microbiota Penetration with Restored Autography in Interleukin-10-gene-deficient Mice Jing Sun Departments of Gastroenterology, Wuxi People's Affiliated to Nanjing Medical P331 Relationship between endoscopic scores and and histological scores in ulcerative colitis. Xuyang Dong The First Affiliated of Zhengzhou P332 IHAP (combination of interleukin-6, hemoglobin, albumin and platelet count) score can accurately assess intestinal inflammation of Crohn's disease changqin liu gastroenterology department, shanghai tenth people's hospital of tongji university P333 The efficacy and safety of cyclophosphamide for intestinal Behcet s disease Tingting Liu Department of Gastroenterology, Peking Union Medical College, Chinese Academy of Medical Science & Peking Union Medical College, Beijing, China. P334 The role of ion transporter in the pathogenesis of IBD Fang Xiao Department of Gastroenterology, Tongji of Tongji, Wuhan 430030, Hubei Province, China. P335 The rural incidence and prevalence of in China Tingting Liu Department of Gastroenterology, Peking Union Medical College, Chinese Academy of Medical Science & Peking Union Medical College, Beijing, China. P336 The real-world outcomes of vedolizumab induction treatment in patients with active Ulcerative Colitis in China: a multicenter retrospective study Jian Tang the Department of Gastroenterology, the Sixth Affiliated,Sun Yat-sen P337 The Urbanization-induced Intestinal Flora Imbalance May Participate in the Pathogenesis of Crohn's Disease Xiaozhi Li of Sun Yat-sen, 58 Zhongshan II Road, Guangzhou P338 A Low FODMAP Diet can reduce gastrointestinal symptoms in patients with inflammatory bowel disease: A Systematic Review and Meta-analysis Ziheng Peng Department of Gastroenterology, Xiangya, Central South P339 Establishment of a prediction model for reoperation risk of Crohn's disease and the impact of postoperative drug medications on reoperation rate Mingyue Guo Peking Union Medical College

P340 Effect of ulceration on the efficacy and safety of endoscopic balloon dilatation in the treatment of Crohn's disease strictures Jiachen Sun The Sixth Affiliated of Sun Yat-sen P341 The intestinal parasitic infections in patients with inflammatory bowel disease Silan Shen Department of Gastroenterology, West China, Sichuan P342 Notopterol suppress the inflammatory responses in C57BL/6 mice with DSSinduced Daoping Si Zhenjiang first people's hospital P343 Prevalence and clinical features of sarcopenia in Korean patients with inflammatory bowel disease Kwangwoo Nam Department of Gastroenterology, Dankook, Dankook College of Medicine P344 Ecological and Network Analyses for the Fecal Microbiome in Ulcerative Colitis (UC) Yang Sun The First Affiliated of Kunming Medical U P345 Diagnostic value of inflammatory indices in patients with and moderate-to-severe Song Wang of USTC, Division of Life Sciences and Medicine, of Science and of China P346 Spicy food is the top one diet risk factor for the relapse and exacerbation of Inflammatory bowel disease Kexin Chen Department of Gastroenterology, West China, Sichuan, Chengdu, China. P347 Regulating effect of mitochondrial ribosomal protein S18B on inflammatory bowel disease by respiratory chain Lili Li Department of Gastroenterology, West China, Sichuan, P348 Efficacy and safety of endoscopic stricturotomy or balloon dilatation combined with local injection of betamethasone in Crohn's disease strictures Junrong Chen The Sixth Affiliated of Sun Yat-sen P349 The role of Akkermansia muciniphila in protecting against Dextran Sulfate Sodium induced colitis Mingshan Jiang Wset China P350 Impact of Crohn s disease on working life: Discovering the truth in Chinese patients Yu Peng Department of Gastroenterology, Xiangya, Central South P351 Epstein Barr Virus Contributing to the Differential Diagnosis of Primary Intestinal Epstein Barr Virus-associated Lymphoproliferative Disorders and Crohn s Disease Chunxiang Ma Department of Gastroenterology, West China, Sichuan P352 Vitamin D level is associated with clinical outcomes in Chinese patients with Crohn s disease Xiaomei Song Department of Gastroenterology, Chongqing General, of Chinese Academy of Sciences P353 Azathiopurine-induced Leukopenia and Evaluation of Therapeutic Effects of Diyushengbai Tablet in Patients with Cohn s Disease Zhen Zeng Department of Gastroenterology, West China, Sichuan P354 Age at onset, maintenance therapy and erythrocyte sedimentation rate are independent risk factors for anal fistula in Crohn s disease Yu Peng Department of Gastroenterology, Xiangya, Central South P355 IL10 Protects Intestinal Stem Cells Against the Damage Induced by Tumor Necrosis Factor-Alpha Huan He South China of, School of Medicine P356 Effect of Shenling Baizhu San on lipid metabolism and intestinal barrier of UC with Pi (Spleen) deficiency Ziyu Lian Jiangsu Province of Traditional Chinese Medicine P357 Comparation between the effect of two- and three stage total proctocolectomy plus ileal pouch anal anastomosis on clinical outcome of Yu Zeqian Nanjing P358 The role of Protease-activated receptor-1 on chronic colitis-associated intestinal fibrosis Jia Song The Second of Hebei Medical P359 Relationship between mitochondrial DNA copy number and Lu Jiajie People's of Xinjiang Uygur Autonomous Region P360 Early predictors of long-term maintenance and remission of glucocorticoid resistance to moderate and severe treated with Yuchang Zhixie decoction combined with infliximab Zhiguo Guo Suzhou of Anhui Medical, P361 Analysis of Colonic Mucosal Hepcidin Expression in Patients with Ulcerative Colitis by Gender. Wang Yang Hebei Medical P362 Acupuncture for sleep disorders improves by downregulating HIF expression wang jing Department of Gastroenterology and Hepatology, Tianjin Medical General P363 Construction of co-expression modules related to sumoylation in DSS-induced colitis utilizing WGCNA Xuanfu Chen Peking Union Medical College, Peking Union Medical College, Chinese Academy of Medical Sciences P364 Risk for malignancies and chemopreventive effect of statin, metformin and aspirin in Korean patients with : A nationwide population-based study Eun Oh Eulji General, Eulji School of Medicine P365 P366 Risk for colorectal cancer and chemopreventive effect of statin, metformin and aspirin in Korean patients with : A nationwide population-based study Risks for colorectal cancer and biliary cancer according to accompanied primary sclerosing cholangitis in Korean patients with : A nationwide population-based study Eun Hye Oh Eulji General, Eulji School of Medicine Eun Hye Oh Eulji General, Eulji School of Medicine P367 Study on the characteristics of gut microbiota in the early stage of Crohn's disease Xianzong Ma Department of Gastroenterology, Seventh Medical Center of Chinese PLA General, P368 Construction of Symptom Assessment Scale in Individuals with inflammatory bowel disease lv hongli General of the Eastern Theater Command P369 Differentiation model between intestinal tuberculosis and Crohn's disease using SVM Yu Li Zhongshan affiliated to Fudan P370 The new HDAC1 inhibitor CBUD-1001 Enhances TRAIL-induced Apoptosis in Colorectal Cancer Cells Min Woo Shin Department of Internal Medicine, Jeonbuk National Medical School P371 Metformin alleviates inflammation through suppressing FASN-dependent palmitoylation of Akt. Wenfang Xiong Nanjing Drum Tower, The Affiliated of Nanjing Medical School P372 Bidirectional association between alopecia areata and celiac disease: a metaanalysis Won Ji Song Department of Dermatology, Seoul National P373 Comparison of Clinical Outcome as Relapse Before and After Introduction of Biological Agents in Pediatric Ulcerative Colitis Yiyoung Kwon Samsung medical center P374 Shikonin Contributes to Intestinal Epithelial Cell Differentiation through PKM2/NRF2-mediated Polyol Pathway Ling Huang Department of Gastroenterology, Guangzhou Women and Children s Medical Center P375 Fibroblasts inhibit mucosal barrier function by secreting WNT2B to activate the WNT/β-catenin signaling pathway in intestinal epithelial cells Xiao Shuzhe Guangzhou Women and Children s Medical Center P376 An effective method to identify clean resection margin and to help reduce postoperative endoscopic recurrence in ileocolic Crohn's disease Jiaxin Zou Guangdong Institute of Gastroenterology, Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, The Sixth Affiliated, Sun Yat sen, 26 Yuancun Erheng Rd, P377 Disease course and clinical outcomes in Taiwan Crohn s Disease patients with perianal fistula: a nationwide-based study Meng-Tzu Weng Departments of Internal Medicine, National Taiwan P378 Correlation between Magnetic Resonance Enterography and ileo-colonoscopy for assessment of disease activity in terminal ileal Crohn s disease Chandan Kakkar Dayanand Medical College and, Ludhiana, India P379 Direct Healthcare Cost Utilization in the First year of Inflammatory Bowel Disease Diagnosis: A binational study Hee Seung Hong Department of Gastroenterology, Asan Medical Center, of Ulsan College of Medicine P380 Endoscopic and pathologic findings of the upper gastrointestinal tract involvement of Crohn s disease in Korea: a prospective cohort study Ga Hee Kim Department of Gastroenterology, Asan medical center, of Ulsan College of Medicine P381 Inflammatory bowel disease(ibd)treatment Muhammad Zulqarnain Zhejiang Chinese Medical P382 The Clinical Outcomes of Very Early-Onset Inflammatory Bowel Disease in Taiwan Jia-Feng Wu National Taiwan P383 Clostridium butyricum regulates T-helper 17 cells-related immune response in dextran sodium sulfate-induced colitis mice by targeting Toll-like receptor 2 Ying Xie Shengjing of China Medical

P384 Early Fecal Microbiome Transfer after donor defecation predicts response in patients with active Arshdeep Singh Dayanand Medical College and, Ludhiana, India P385 Clinical course of COVID-19 in patients with inflammatory bowel disease in Korea: A KASID multicenter study Jin Wook Lee Department of Gastroenterology, Asan Medical Center, of Ulsan College of Medicine P386 Inflammatory Bowel Disease: Three Decadal Status and Trends from Global Burden of Disease Study 2019 Khushdeep Dharni Dayanand Medical College and, Ludhiana, India P387 Additive effect of probiotics (Mutaflor ) on 5-aminosalicylic acid therapy in patients with Soo-Kyung Park Kangbuk Samsung, Sungkyunkwan School of Medicine P388 Continuous intravenous cyclosporine therapy improves short term prognosis in patients with severe refractory to multiple molecular target therapies. Yuta Matsubara Internal Medicine, Keio School of Medicine P389 Reversion of gut microbiota during the recovery phase in pa-tients with asymptomatic or mild COVID-19: longitudinal study Han-Na Kim Kangbuk Samsung, Sungkyunkwan School of Medicine P390 Metformin Affects Gut Microbiota Composition and Diversity Associated with Amelioration of Dextran Sulfate Sodium-Induced Colitis in Mice Xin Li First Affiliated of Nanchang P391 Machine Learning-based Classification for Diagnosis of Colorectal Cancer Stage Using Recurrent Neural Network Model Algorithm Rifaldy Fajar Computational Biology Laboratory, Yogyakarta State, Indonesia P392 Effect of smoking on the development and outcomes of inflammatory bowel disease in Asians Chien-Chih Tung National Taiwan P393 Significance of anemia in Asian patients with inflammatory bowel disease Po-Yen Hsiao Department of Internal Medicine, National Taiwan, Taipei, Taiwan P394 Evaluation of Nutritional Status in Patients with Inflammatory Bowel Disease in India Arshdeep Singh Dayanand Medical College and, Ludhiana, India P395 The p21-activated kinase 4 plays critical role in regulating cell survival, EMT, angiogenesis and cancer stemness in colorectal cancer microenvironment. Se Lim Kim Department of Internal Medicine, Jeonbuk National Medical School P396 The risk of tuberculosis in patients with inflammatory bowel disease treated with vedolizumab or ustekinumab in South Korea Myeong Geun Choi Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Asan Medical Center, of Ulsan College of Medicine P397 Serum Leucine-rich alpha 2 glycoprotein as a novel surrogate marker of endoscopic activity in patients with Crohn s disease. Ryoya Sakakibara Internal Medicine, Keio School of Medicine P398 Long-term Safety and Efficacy of Fecal Microbiota Transplantation in inflammatory bowel disease: Up to 5-year Data from Hong Kong Yuk Kam Yau Center for Gut Microbiota Research, Faculty of Medicine, The Chinese of Hong Kong P399 The Impacts of COVID-19 Pandemic on Patient Perceptions and Inflammatory Bowel Disease Care: A Multicenter Study in Taiwan Chen-Shuan Chung Internal Medicine, Far Eastern Memorial P400 Risk of cervical cancer in incident Ulcerative colitis during the first 10 years after diagnosis: a nationwide population-based study Ha Lim Jo Department of Internal Medicine, Yonsei Wonju College of Medicine P401 Effect and mechanism of ZIP7 on the regulation of endoplasmic reticulum stress in intestinal epithelial tight junction protein ZO-1 Zhongxia Chen The Affiliated Wuxi People's of Nanjing Medical P402 Lactococcus formosensis inhibits intestinal smooth muscle movement through Transgelin in functional constipation Simin Zhou Tianjin Medical General P403 Development of Global Inflammatory Bowel Disease Visualisation of Epidemiology Study in the 21st Century (GIVES-21) to define disease burden and dietary risk factors in newly industrialised regions Joyce Wing Yan Mak The Chinese of Hong Kong P404 Identification of fibroblast heterogeneity in the murine colon Yuya Hagihara Internal Medicine, Keio School of Medicine P405 Development of Machine Learning Models to Predict Early Disease Progression in Crohn s disease: Results from the IMPACT Study Jaeyoung Chun Department of Internal Medicine, Gangnam Severance, Yonsei College of Medicine P406 IL-1R-mediated mechanisms of IL-10 production by gut macrophages Noritaka Hibi Center for Advanced IBD Research and Treatment, Kitasato Kitasato Institute P407 Depression in Patients with Inflammatory Bowel Disease is associated with increased risk of Dementia and Parkinson s disease: A Nationwide, Population- Based Study Kookhwan Choi Department of Internal Medicine and Liver Research Institute, Seoul National College of Medicine P408 Jaundice in a primary sclerosing cholangitis patient a new cause in a new era Nik Arsyad Nik Muhamad Affendi of Malaya Medical Centre P409 Real world experience on the efficacy and safety of Ustekinumab in Crohn s disease in an Asian population: A preliminary report Nik Arsyad Nik Muhamad Affendi Malaya Medical Centre P410 A novel role of PCDH20 in the maintenance of intestinal homeostasis in Crohn s disease Shanshan Huang, Sun Yat-sen P411 The persistence of oral 5-aminosalicylic acid monotherapy in : a real-world study Chen-Wang Chang Division of Gastroenterology, Department of Internal Medicine, Mackay Memorial P412 Risk of colorectal cancer of incident Crohn s disease during the first 10 years after diagnosis: A nationwide population-based study Hee Man Kim Department of Internal Medicine, Yonsei Wonju College of Medicine P413 The Link of Appendiceal Mucocele and Inflammatory Bowel Disease: a Comprehensive Systemic Review Chen-Wang Chang Division of Gastroenterology, Department of Internal Medicine, Mackay Memorial P414 Fecal Microbial Transplantation in Inflammatory Bowel Disease Patients with Refractory or Recurrent Clostridioides Difficile Infection Puo-Hsien Le Chang Gung Microbiota Therapy Center, Chang Gung Memorial P415 Vedolizumab-related agranulocytosis with Epstein-Barr virus esophagitis: A case report Puo-Hsien Le Department of Gastroenterology and Hepatology, Chang Gung Memorial, Linkou Branch P416 Typical esophageal ulcer may help the diagnosis of intestinal Behçet s disease Chen Xie of Soochow P417 Impact of timing of immunomodulator use on first intestinal resection in Crohn s Disease with poor prognostic factors : a nationwide population-based cohort study 2004-2015; Jae Jun Park Department of Internal Medicine, Severance, Yonsei College of Medicine P418 Establishing correlation between faecal microbial taxa and different phases of disease in a north Indian cohort Garima Juyal hool of Biotechnology, Jawaharlal Nehru, New Delhi, India P419 P420 Gut microbial and metabolomic profiles of patients with in response to FMT Clostridium butyricum-derived Extracellular Vesicles Fuel Regulatory Macrophages Reprogramming and Remodel the Gut microbiota to Prevent Ulcerative Colitis Manasvini Markandey All India Institute of Medical Sciences Liping Liang shenzhen hospial,southern medical university P421 Rebleeding risk factors following endoscopic therapy of small-bowel lesions with device-assisted enteroscopy Yuna Kim Department of Internal Medicine and Institute of Gastroenterology, Yonsei College of Medicine P422 Clinical characteristics of newly diagnosed adult patients with Crohn's disease in Japan: Interim analysis of icrest-cd Katsuyoshi Matsuoka Internal Medicine, Toho Sakura Medical Center, Sakura, Chiba, Japan;