What Do 21st Century Medical Students Need to Know about Biomedical and Health Informatics?



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What Do 21st Century Medical Students Need to Know about Biomedical and Health Informatics? References William Hersh, MD Professor and Chair Department of Medical Informatics & Clinical Epidemiology Oregon Health & Science University Portland, OR, USA Email: hersh@ohsu.edu Web: www.billhersh.info Blog: http://informaticsprofessor.blogspot.com Anonymous (2008). Information Behaviour of the Researcher of the Future. London, England, Centre for Information Behaviour and the Evaluation of Research. http://www.bl.uk/news/pdf/googlegen.pdf Anonymous (2011). Health Information Technology & Privacy. Philadelphia, PA, American College of Physicians. http://www.acponline.org/advocacy/where_we_stand/policy/hit_privacy.pdf Anonymous (2012). Population Health Management - A Roadmap for Provider- Based Automation in a New Era of Healthcare. New York, NY, Institute for Health Technology Transformation. http://ihealthtran.com/pdf/phmreport.pdf Benson, T (2012). Principles of Health Interoperability HL7 and SNOMED (Health Information Technology Standards), Second Edition. New York, NY, Springer. Berwick, DM and Hackbarth, AD (2012). Eliminating waste in US health care. Journal of the American Medical Association. 307: 1513-1516. Berwick, DM, Nolan, TW, et al. (2008). The triple aim: care, health, and cost. Health Affairs. 27: 759-769. Coiera, E (2007). Putting the technical back into socio- technical systems research. International Journal of Medical Informatics. 76(Supp 1): 98-103. Collins, FS (2010). The Language of Life: DNA and the Revolution in Personalized Medicine. New York, NY, Harper. Detmer, D, Bloomrosen, M, et al. (2008). Integrated personal health records: transformative tools for consumer- centric care. BMC Medical Informatics & Decision Making. 8: 45. http://www.biomedcentral.com/1472-6947/8/45 Detmer, DE, Lumpkin, JR, et al. (2009). Defining the medical subspecialty of clinical informatics. Journal of the American Medical Informatics Association. 16: 167-168. Doty, CA (2008). Delivering Care Anytime, Anywhere: Telehealth Alters the Medical Ecosystem. Oakland, CA, California Health Care Foundation. http://www.chcf.org/topics/view.cfm?itemid=133787 Fridsma, D (2013). Interoperability Standards Shades of Gray. Health IT Buzz, February 8, 2013. Friedman, CP (2009). A 'fundamental theorem' of biomedical informatics. Journal of the American Medical Informatics Association. 16: 169-170. Friedman, CP (2012). What informatics is and isn't. Journal of the American Medical Informatics Association. 20: 224-226. Friedman, CP, Wong, AK, et al. (2010). Achieving a nationwide learning health system. Science Translational Medicine. 2(57): 57cm29. http://stm.sciencemag.org/content/2/57/57cm29.full Gardner, RM, Overhage, JM, et al. (2009). Core content for the subspecialty of clinical informatics. Journal of the American Medical Informatics Association. 16: 153-157.

Greene, SM, Reid, RJ, et al. (2012). Implementing the learning health system: from concept to action. Annals of Internal Medicine. 157: 207-210. Greiner, AC and Knebel, E, Eds. (2003). Health Professions Education: A Bridge to Quality. Washington, DC, National Academies Press. Hersh, W (2004). Health care information technology: progress and barriers. Journal of the American Medical Association. 292: 2273-2274. Hersh, W (2008). Health and Biomedical Informatics: Opportunities and Challenges for a Twenty- First Century Profession and its Education. IMIA Yearbook of Medical Informatics 2008. A. Geissbuhler and C. Kulikowski. Stuttgart, Germany, Schattauer: 138-145. Hersh, W (2009). A stimulus to define informatics and health information technology. BMC Medical Informatics & Decision Making. 9: 24. http://www.biomedcentral.com/1472-6947/9/24/ Hersh, W (2010). The health information technology workforce: estimations of demands and a framework for requirements. Applied Clinical Informatics. 1: 197-212. Hersh, W (2013). Eligibility for the Clinical Informatics Subspecialty. Infromatics Professor, January 11, 2013. http://informaticsprofessor.blogspot.com/2013/01/eligibility- for- clinical- informatics.html Hersh, W (2013). What Do Twenty- First Century Healthcare Professional Students Need to Learn About Informatics? Informatics Professor, January 17, 2013. http://informaticsprofessor.blogspot.com/2013/01/what- do- twenty- first- century- healthcare.html Hersh, WR (2002). Medical informatics - improving health care through information. Journal of the American Medical Association. 288: 1955-1958. Hersh, WR (2006). Who are the informaticians? What we know and should know. Journal of the American Medical Informatics Association. 13: 166-170. Hersh, WR (2009). Information Retrieval: A Health and Biomedical Perspective (3rd Edition). New York, NY, Springer. Hersh, WR, Hickam, DH, et al. (2006). Diagnosis, access, and outcomes: update of a systematic review on telemedicine services. Journal of Telemedicine & Telecare. 12(Supp 2): 3-31. Kernisan, L (2013). What Will Tomorrow s Doctor Look Like? The Health Care Blog, March 8, 2013. http://thehealthcareblog.com/blog/2013/03/08/what- my- home- renovation- taught- me- about- practicing- medicine/ Krohn, R and Metcalf, D (2012). mhealth: From Smartphones to Smart Systems. Chicago, IL, Healthcare Information Management Systems Society. Kuperman, GJ (2011). Health- information exchange: why are we doing it, and what are we doing? Journal of the American Medical Informatics Association. 18: 678-682. Lehmann, HP, Abbott, PA, et al. (2011). Aspects of Electronic Health Record Systems. New York, NY, Springer. Lykke, F, Holzworth, M, et al. (2011). Telemedicine: An Essential Technology for Reformed Healthcare. Falls Church, VA, Computer Sciences Corp. http://www.csc.com/health_services/insights/64941- telemedicine_an_essential_technology_for_reformed_healthcare Miller, HD, Yasnoff, WA, et al. (2009). Personal Health Records: The Essential Missing Element in 21st Century Healthcare. Chicago, IL, Healthcare Information and Management Systems Society. Osheroff, JA, Teich, JM, et al. (2012). Improving Outcomes with Clinical Decision Support: An Implementer's Guide, Second Edition. Chicago, IL, Healthcare Information Management Systems Society. Ricciardi, L, Mostashari, F, et al. (2013). A national action plan to support consumer engagement via e- health. Health Affairs. 32: 376-384. Richesson, RL and Andrews, JE, Eds. (2012). Clinical Research Informatics. New York, NY, Springer.

Safran, C, Shabot, MM, et al. (2009). ACGME program requirements for fellowship education in the subspecialty of clinical informatics. Journal of the American Medical Informatics Association. 16: 158-166. Sánchez- Mendiola, M, Martínez- Franco, AI, et al. (2013). Development and implementation of a biomedical informatics course for medical students: challenges of a large- scale blended- learning program. Journal of the American Medical Informatics Association. 20: 381-387. Scott, J, Kishore, S, et al. (2013). America's Healthcare Crisis: A Prescription for Breaking the Cycle. Huffington Post, February 21, 2013. http://www.huffingtonpost.com/ali- ansary/future- medical- education_b_2699375.html Shortliffe, EH and Cimino, JJ, Eds. (2006). Biomedical Informatics: Computer Applications in Health Care and Biomedicine. New York, NY, Springer. Silverman, H, Cohen, T, et al. (2012). The evolution of a novel biomedical informatics curriculum for medical students. Academic Medicine. 87: 84-90. Smith, M, Saunders, R, et al. (2012). Best Care at Lower Cost: The Path to Continuously Learning Health Care in America. Washington, DC, National Academies Press. Straus, SE, Glasziou, P, et al. (2010). Evidence- Based Medicine: How to Practice and Teach it, 4e. New York, NY, Churchill Livingstone. Wakefield, DS, Kruse, RL, et al. (2012). Consistency of patient preferences about a secure Internet- based patient communications portal: contemplating, enrolling, and using. American Journal of Medical Quality. 27: 494-502.

What Do 21 st Century Medical Students Need to Know about Biomedical and Health Informa@cs? William Hersh, MD Professor and Chair Department of Medical Informa@cs & Clinical Epidemiology Oregon Health & Science University Portland, OR, USA Email: hersh@ohsu.edu Web: www.billhersh.info Blog: hpp://informa@csprofessor.blogspot.com 1 Before we can teach informa@cs, we must define it I get asked this so oten that I keep a Web site hpp://www.billhersh.info/wha@s/ And a blog hpp://informa@csprofessor.blogspot.com I have also wripen ar@cles about it Medical informa@cs: improving healthcare through informa@on (Hersh, 2002) But there are barriers (Hersh, 2004) Characteriza@on of and changes in the profession (Hersh, 2006) Many career opportuni@es as well (Hersh, 2008) Reconciling defini@ons of terms (Hersh, 2009) The informa@cs professional workforce (Hersh, 2010) 2 1

Let us start by defining informa@cs The discipline focused on the acquisi@on, storage, and use of informa@on in a specific sebng or domain (Hersh, 2009) Is more about informa@on than technology Some@mes defined as ac@vity at the intersec@on of people, informa@on, and technology The science of sociotechnical systems (Coiera, 2007) (SUNY Buffalo) 3 What informa@cs is and isn t (Friedman, 2012) Is Cross- training where basic informa@onal sciences meets a biomedical applica@on domain Relentless pursuit of assis@ng people Is not Scien@sts or clinicians @nkering with computers Analysis of large data sets Fundamental theorem (Friedman, 2009) Goal of informa@cs is: Goal is not: 4 2

Classifica@on of biomedical and health informa@cs Imaging Informa@cs Research Informa@cs {Clinical field} Informa@cs Consumer Health Informa@cs Bioinforma@cs (cellular and molecular) Legal Informa@cs Medical or Clinical Informa@cs (person) Biomedical and Health Informa@cs Public Health Informa@cs (popula@on) Chemoinforma@cs Informa@cs = People + Informa@on + Technology (Hersh, 2009; adapted from Shortliffe, 2006) 5 Informa@cs now viewed as a core competency for health professionals According to Ins@tute of Medicine report, the modern healthcare professional must have competency in informa@cs as part of larger goal to provide pa@ent- centered care (Greiner, 2003) Informa@cs competency is not just computer literacy! The Google genera@on does not necessarily have good informa@on skills (CIBER, 2008) 6 3

People in the healthcare system who need competence in informa@cs Consumers/pa@ents And their families and caregivers Clinicians Physicians, nurses, and others Others in the healthcare system Administrators, librarians, financial personnel, etc. Informa@cians Researchers, professionals 7 Focus of this talk is on clinicians, specifically medical students Principles for informa@cs educa@on of medical students Must approach with perspec@ve of what type of physicians we want them to be Educa@on should be focused on informa@cs as a tool for beper, safer, and cheaper healthcare Some visions to guide us www.tomorrowsdoctor.org (ScoP, 2013) Inspired by: Smith, 2012 Also of note: Kernisan, 2013 My own view: Hersh, 2013 8 4

US healthcare system is broken in many ways and needs fixing Ac@on must be taken to address (Smith, 2012) $750B in waste (out of $2.5T system) 75,000 premature deaths Sources of waste from Berwick (2012) Unnecessary services provided Services inefficiently delivered Prices too high rela@ve to costs Excess administra@ve costs Missed opportuni@es for preven@on Fraud One vision for repair is the IOM s learning healthcare system (Smith, 2012) hpp://www.iom.edu/reports/2012/best- Care- at- Lower- Cost- The- Path- to- Con@nuously- Learning- Health- Care- in- America.aspx 9 What is the learning health system? Pursuit of Berwick s triple aim of beper health, beper care, and lower cost (Berwick, 2008) A large role for informa@cs (Friedman, 2010) Elaborated in recent IOM report (Smith, 2012) 10 5

What will tomorrow s doctor look like? (Kernisan, 2013) Be comfortable with the e- pa@ents Engage in shared decision- making Be able to coordinate and cooperate with other clinicians Be comfortable with con@nuous quality improvement (CQI) and plan- do- study- act (PDSA) cycles Be comfortable learning new ways of prac@ce Be comfortable with well- designed technology 11 What informa@cs knowledge and skills must they have? (Hersh, 2013) Computer literacy Finding informa@on and applying to pa@ent care Proper role and use of the pa@ent record Pa@ent engagement Telemedicine and telehealth Popula@on- based care Personalized medicine and genomics Clinical research 12 6

Computer literacy A basic skill that is a prerequisite and not an end in itself Computer literacy is not informa@cs literacy but a requirement for it Basic skills include Computer and its core applica@ons produc@vity applica@ons Basic Internet applica@ons email, Web, basic searching Use of mobile devices smartphones and/or tablets 13 Finding and applying informa@on Informa@on retrieval, also called search or knowledge management (Hersh, 2009) Must be able to Formulate clinical ques@on into an answerable one Select the proper search tool Pubmed and other NLM databases, textbooks, Na@onal Guidelines Clearinghouse, US government sites (e.g., CDC), and even Google (when appropriate) Be a power searcher Pubmed Clinical Queries, advanced features of most search systems 14 7

Finding and applying informa@on (cont.) Also must be able to cri@cally appraise search results, i.e., apply evidence- based medicine (EBM) (Straus, 2010) Ask an answerable ques@on Find the best evidence to answer the ques@on Treatment/interven@on randomized controlled trials (RCTs) or systema@c reviews thereof Diagnosis determina@on of test characteris@cs (e.g., sensi@vity, specificity) and strategies Apply to the pa@ent situa@on 15 Proper role and use of the pa@ent record Evolu@on of pa@ent record from documenta@on to source of data and informa@on to improve individual and popula@on care Essen@al tools include Electronic health record (EHR) (Lehmann, 2011) Health informa@on exchange (HIE) (Kuperman, 2011) 16 8

Principles of EHR use Adhering to standards use of those ready for prime @me (Fridsma, 2013) Achieving system and data interoperability (Benson, 2012) Appropriately and op@mally implemen@ng clinical decision support (Osheroff, 2012) Maintaining security to assure privacy and confiden@ality (ACP, 2011) 17 Other aspects of the EHR Quality measurement and improvement Quality measures process vs. outcome Using EHR to streamline collec@on of quality data Pay for performance, accountable care, and other approaches to quality improvement Pa@ent engagement (Riccardi, 2013) proper use of Personal health record (PHR) (Detmer, 2008; Miller, 2009) Pa@ent portals (Wakefield, 2012) 18 9

Telemedicine and telehealth Be able to par@cipate in case where @me and distance separate pa@ents and providers Telemedicine (Lykke, 2011) major applica@ons include (Hersh, 2006) Store- and- forward asynchronous, care not in real- @me Office/hospital- based exper@se at a distance Home- based pa@ents gebng care in place Telehealth (Doty, 2008) many defini@ons, related terms include ehealth, mhealth (Krohn, 2012), etc. 19 Popula@on- based care (IHT2, 2012) Clinician team will be caring for popula@ons of pa@ents Must be able to view care needs and results across their pa@ent popula@on When a new test or treatment comes along that is determined to be highly effec@ve, must be able to quickly iden@fy pa@ents who are candidates for it Must also be able to iden@fy outliers in popula@on who require interven@on, such as those with excessively high blood pressure or blood sugar, missed appointments or screening tests, or those at risk for hospital (re- )admission 20 10

Personalized medicine and genomics Modern clinician should have understanding of how genomics and related areas transforming our understanding of maintaining health, diagnosing disease, and trea@ng it If vision of personalized medicine comes to pass, the 21 st century clinician will need the help of decision support and other tools for help in applying it to individual pa@ents (Collins, 2011) 21 Clinical research Must understand the differences and value contributed by experimental and observa@onal studies Ideally, the student will have par@cipated in research while in training Even if not, should understand issues like data quality, study design, and the limita@ons that come from the sharp focus perspec@ve of a clinical study Should also be able to par@cipate in clinical research studies and have basic understanding of informa@cs issues (Richesson, 2012) 22 11

Opera@onalize learning health system in own environment (Greene, 2012) Many opportuni@es, including the new subspecialty of clinical informa@cs Recogni@on of importance of EHRs and other IT applica@ons focused on facilita@ng clinical care, clinical and transla@onal research, quality improvement, etc. (Detmer, 2010) Core curriculum (Gardner, 2009) Training requirements (Safran, 2009) Growing number of health care organiza@ons hiring physicians into informa@cs roles, exemplified by (but not limited to) the Chief Medical Informa@cs Officer (CMIO) Approval by ABMS in Sept., 2011 to apply to all special@es Administra@ve home: American Board of Preven@ve Medicine (ABPM) www.theabpm.org For more informa@on (Hersh, 2013): hpp://informa@csprofessor.blogspot.com/2013/01/eligibility- for- clinical- informa@cs.html 24 12

Role of educators Informa@cs educators must innovate with other medical educators Integra@on into clinical curriculum many good examples, some published University of Arizona (Silverman, 2012) Universidad Nacional Autónoma de México (UNAM) (Sánchez- Mendiola, 2013) 25 Some final thoughts Change can be hard! To promote informa@cs educa@on for medical students, need to promote value of informa@cs clinically, from improved care to learning health system As use of informa@cs tools, prac@cing physicians need competence in using tools and informa@cs physicians must provide guidance and leadership 26 13