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BILAG 1: Søgeprotokol med søgestreng Hvilken evidens er der for, at stimulation af akupunkturpunktet P6, sammenlignet med konventionel antiemetika, reducerer forekomsten af PONV Søgeord: Acupuncture, acupuncture therapy, acupuncture points, acupoint, acupressure, transcutaneous electric nerve stimulation, TENS, percutaneous electrical nerve stimulation, electro acupuncture, postoperative nausea and vomiting, PONV, postoperative emesis, established PONV, antiemetics, antiemetic effect. Søgeperiode: Inkludér Ekskludér Januar 1995 december 2012 Side 1

Studiepopulation: Patienter med risiko for udvikling af PONV eller med etableret PONV. Litteraturtyper: Systematiske reviews Metaanalyser Randomiserede kontrollerede undersøgelser Kontrollerede kliniske undersøgelser Clinical guidelines Kliniske nøgleområder: Non-farmakologisk antiemetisk behandling PONV Artikler med studier der udelukkende omhandler behandling af kvalme og opkastning efter kemoterapi & under graviditet. Artikler udelukkende med børn. Artikler på andre sprog end engelsk, tysk og nordisk. Databaser: PubMed The Cochrane Library Web of Science EMBASE CINAHL Internetsider: Joanna Briggs Institute National Guideline Clearinghouse SIGN Trip Ugeskrift for læger KUFAB CCESCAM Manuel søgning: Artiklernes referencelister Side 2

Søgestreng Dato Database Søgetermer Limits Antal hits 15.06.12 Medline Acupuncture OR Acupuncture [Mesh] OR Acupuncture Therapy [Mesh] OR Acupuncture therapy OR Acupuncture points OR Acupuncture Points [Mesh] OR Acupoint* OR Acupressure OR Acupressure [Mesh] OR Transcutaneous electric nerve stimulation OR Transcutaneous Electric Nerve Stimulation [Mesh] OR Transcutaneous electrical stimulation OR percutaneous electric nerve stimulation OR Percutaneous electrical nerve stimulation OR transdermal electrostimulation OR Transcutaneous electrical nerve stimulation OR Publication date 01.01.1995 til 31.12.2012 Clinical trial, Controlled clinical trial, Guideline, Metaanalysis, Practice guideline, Randomized controlled trial, Review, Systematic Reviews. Danish, English, German, Norwegian, Swedish 85 Side 3

transcutaneous nerve stimulation OR Transcutaneous electric stimulation OR TENS OR Electro-acupuncture OR Electro acupuncture OR Electroacupuncture OR Electroacupuncture [Mesh] PONV Postoperative Nausea and Vomiting [Mesh] OR Postoperative Nausea and Vomiting OR Postoperative Nausea OR Postoperative Vomiting OR Postoperative Emesis OR Postoperative Emeses OR established PONV Antiemetic* Antiemetic drugs OR antiemetics OR anti emetics OR antiemetic agents OR antiemetic effect OR antiemetic effects OR anti emetic effects OR antiemetic effects OR anti-emetic effect Side 4

OR anti emetic effect OR Antiemetics [Mesh] 14.6.12 Embase Acupuncture OR acupressure OR Electroacupuncture OR Acupuncture [Thesaurus] OR acupuncture therapy [Thesaurus] OR acupuncture point*[thesaurus] OR acupoint [Thesaurus] OR acupressure [Thesaurus] OR transcutaneous nerve stimulation OR transcutaneous electrostimulation OR transcutaneous nerve stimulation [Thesaurus] OR percutaneous electric nerve stimulation OR percutaneous electrical nerve stimulation OR TENS OR transcutaneous electric nerve stimulation OR transcutaneous electrical nerve stimulation OR transcutaneous electrical stimulation OR transcutaneous electrostimulation [Thesaurus] OR transcutaneous electric nerve stimulation [Thesaurus] OR electroacupuncture OR electro acupuncture OR electro-acupuncture 1995 current. Danish, English, Norwegian, Swedish 174 Side 5

[Thesaurus] Postoperative nausea and vomiting [Thesaurus] OR PONV OR postoperative nausea OR postoperative vomiting OR postoperative emesis OR postoperative emeses [Thesaurus] OR established ponv [Thesaurus] Antiemetic agent OR antiemetic* OR antiemetic drugs OR antiemetic drug OR anti emetic drug OR antiemetics OR anti emetics OR antiemetic agents OR anti emetic agents OR antiemetic effect OR antiemetic effects OR anti emetic effects OR antiemetic effects OR antiemetic effect OR anti emetic effect [Thesaurus] 15.6.12 Cochrane Acupuncture OR acupuncture therapy OR Acupuncture [Mesh] OR Acupuncture Therapy [Mesh] OR acupuncture therapy OR acupuncture points OR Acupuncture Points [Mesh] OR acupoint OR acupoints OR acupressure OR From 1995 to 2012 122 Side 6

Acupressure [Mesh] OR transcutaneous electric nerve stimulation OR Transcutaneous Electric Nerve Stimulation [Mesh] OR transcutaneous nerve stimulation OR transcutaneous electric stimulation OR TENS OR Electroacupuncture [Mesh] Ponv OR Postoperative Nausea and Vomiting [Mesh] OR established ponv Antiemetic OR antiemetics OR Antiemetics [Mesh] 19.6.12 Web of Science Acupuncture OR acupuncture therapy OR acupuncture points OR acupoint* OR acupressure OR transcutaneous electric nerve stimulation OR transcutaneous electrical stimulation OR percutaneous electric nerve stimulation OR percutaneous electrical nerve stimulation OR transdermal electrostimulation OR transcutaneous electrical From 1995 to 2012 English 71 Side 7

nerve stimulation OR transcutaneous nerve stimulation OR transcutaneous electric stimulation OR TENS OR electroacupuncture OR electro acupuncture OR electro-acupuncture PONV OR postoperative nausea and vomiting OR postoperative nausea OR postoperative vomiting OR postoperative emesis OR postoperative emeses OR established ponv antiemetic* OR antiemetic drug OR antiemetic drugs OR anti-emetics OR anti emetics OR anti emetic agent OR antiemetic agents OR antiemetic effect OR anti-emetic effects OR anti emetic effects OR antiemetic effects OR anti-emetic effect OR anti emetic effect 18.6.12 Cinahl Acupuncture OR MH Acupuncture+ OR acupuncture points OR MH From 1995 to 2012 89 Side 8

Acupuncture Points OR acupoint* OR acupressure OR MH Acupressure+ OR MH Transcutaneous Electric Nerve Stimulation OR transcutaneous electric nerve stimulation OR transdermal electrostimulation OR transcutaneous electric stimulation OR TENS OR MH Electroacupuncture OR acupuncture therap* Danish, English, Norwegian, Swedish ponv OR MH Nausea and Vomiting+ OR postoperative nausea and vomiting OR postoperative nausea OR postoperative vomiting OR postoperative emesis OR postoperative emeses OR established ponv MH Antiemetics+ OR antiemetics OR antiemetic drugs OR antiemetics OR anti emetics OR antiemetic agents OR antiemetic agents OR antiemetic effect* OR anti-emetic effect* OR anti emetic effect* Side 9

Side 10