H1N1 Influenza Pandemic Retrospective



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H1N1 Influenza Pandemic Retrospective Gus Birkhead, MD, MPH New York State Department of Health Outline Epidemiology of H1N1 NYSDOH response Clinical guidance distribution Risk Communication: Media/Educational materials Lessons Learned Continuing Challenges The Pandemic Begins March - Early April 29 28-29 Annual Flu Season is winding down in the N. Hemisphere 28-29 - mild seasonal flu Something is not quite right - Mexico experiencing outbreaks of respiratory and influenza like illness - cases of severe pneumonia and death April 12, 29- Mexico reports: Outbreaks in Veracruz to Pan America Health Organizations 29 Influenza Season #1 Seasonal Influenza 29 Influenza Season #2 H1N1 First Wave 29 Influenza Season #3 H1N1 Second Wave 1

H1N1 Flu Confirmed Cases by Age NYS (excluding NYC), thru 7/2/9 H1N1 Flu Confirmed Case Rate by Age NYS (excluding NYC), thru 7/2/9 Cases Number of 9 8 7 6 4 3 2 1-4 -24 2-49 -64 >=64 Age Group (years) Rate per 1, 4 3 2 1-4 -24 2-49 -64 >=64 Age Group (years) H1N1 Flu Hospitalization Rate by Age NYS (excluding NYC), thru 7/2/9 Rate per million 4 3 2 1-4 -24 2-49 -64 >=64 Age Group (years) Percen nt 4 4 3 3 2 2 1 1 Age Distribution of Hospitalized Seasonal and H1N1 Influenza Cases Seasonal 27-8 < 6 mo 6mo-4-9 yrs 1-17 18-29 yrs yrs Age group yrs Source, CDC Emerging Infections Program 3-49 -64 6+ yrs *April 12 yrs June 3 yrs Source: A. Fiore, CDC H1N1 in Pregnancy Study Studied 788 pregnant women in the US with 29 H1N1 influenza with symptom onset from April through August; 3 died, % of all reported H1N1 influenza deaths. 6-fold increased risk 9 hospitalized women, 11 (22.6%) to an ICU. Early antiviral treatment appeared to be associated with fewer admissions to an ICU and fewer deaths Only 1 death in those treated within 2 days of symptoms. JAMA 21;33(1):117-12 2

H1N1 Influenza Epidemiology Key Points Most cases throughout pandemic relatively mild, low mortality overall Highest hospitalization rate in -4 year age group (6.2/1,) ) Highest mortality rate in -64 year age group (1.77/1,) Some groups at very high risk Pregnant women Excess pediatric deaths NYS DOH Response Process DOH IMS Activated- 4/23/9-6/2/9 Response (64 days) DOH IMS Planning- 6/26/9-1/12/9 (19 days) DOH IMS Response- 1/13/9-2/2/1 (113 days) 286 days IMS activated Vaccination IMS Branch Organization Epidemiology Surveillance Laboratory Surveillance Healthcare Surge/Triage Healthcare Infection Control Occupational Health and Safety Community Mitigation Clinical Management Public Information Risk Communication Informatics Legal Issues Education Long Term Care Emergency Medical Service Border/Tribal Health Stockpile/Logistics IMS Products 39 Situation Reports Developed IMS Conference Calls Conducted - 8 DOH Management Calls Conducted - 18 County Health Department Calls Conducted - 22 MAC Meetings Conducted - 6 Planning Health Commerce System (HCS) September 9, 29-Present 142 notifications of the availability of H1N1 related documents (194, e-mails) Vaccine Campaign - 26 separate transmission by direct emails to, registered providers, 2 separate transmission to 64, registered medical providers (2, emails) 7 H1N1 related documents were posted on HCS resulting in 692,739 downloads and,941,646 access transactions. Vaccine registration/order history - 162,232 access transactions. H1N1 Clinical Guidance Issued by NYSDOH General clinical guidance on H1N1 diagnosis, prophylaxis and treatment; Subsequent updates; Checklist for provider offices on preparedness to deal with H1N1 patients/issues; Advisory on peramivir; Advisory on update on antiviral medication issues (early treatment, compounding, mixing with liquids, IV zanamivir, IV peramivir, dosing errors); One-pager for OB/GYN physicians to encourage consideration of prophylaxis/presummptive treatment and vaccination of pregnant women; Infection Control guidance for facilities. 3

Number of Registered Providers per 1, Population* Clinton Franklin St. Lawrence Number of Local Health Department PODs per County (Open & Closed)* St. Lawrence (18) Franklin (3) Clinton (4) Jefferson Essex Jefferson (89) Essex (24) Lewis Hamilton Warren Oswego Herkimer Niagara Orleans Washington Oneida Monroe Wayne Fulton Saratoga Genesee Onondaga Cayuga Ontario Madison Erie Livingston Montgomery Seneca Wyoming Schenectady Yates Rensselaer Cortland Otsego Albany Chenango Schoharie Tompkins Schuyler ChautauquaCattaraugus Allegany Steuben Greene Tioga Delaware Columbia Chemung Broome Lewis (2) Hamilton (7) Warren (33) Herkimer (2) Oswego (6) Washington (39) Niagara (29) Orleans (28) Oneida (14) Monroe (7) Wayne (3) Fulton (8) Saratoga (42) Genesee (4) Onondaga (3) Cayuga (2) Ontario (8) Madison (28) Montgomery (9) Erie (9) Wyoming (2) Livingston (47) Seneca (23) Schenectady (3) Rensselaer (1) Yates (9) Cortland (41) Otsego (47) Albany (6) Chenango (37) Schoharie (8) Tompkins (73) Chautauqua (3) Cattaraugus (18)Allegany (24) Schuyler (2) Greene (39) Steuben (88) Columbia (39) Tioga (26) Delaware (12) Chemung (12) Broome (83) <= 3 Ulster Dutchess Sullivan <= 1 Ulster (12) Dutchess (3) Sullivan (43) 31-4 41-1 - 6 *Excluding NYC Orange Putnam Westchester Rockland Suffolk Nassau 1-2 2 - - 7 *Excluding NYC Orange (34) Putnam (4) Westchester (3) Rockland (1) Suffolk (42) Nassau (16) > 6 > 7 Richmond 8,, 7,, 6,,,, 8,, 7,, 6,,,, 4,, 3,, 2,, 1,, 4,, 3,, 2,, 1,, Initial Pushes 8,, 8,, 7,, 6,, 7,, 6,,,,,, 4,, 4,, 3,, 3,, 2,, 2,, 1,, 1,, Vaccine Demand > Vaccine Supply Vaccine pushed as quickly as possible. Most of gap seen due to LAIV Vaccine Supply > Vaccine Demand 4

Doses Administered as a Percentage of Doses Shipped Adult Practices - 19% 29 H1N1 INFLUENZA Public Information and Risk Communication Family Practices - 23% OB/GYN Practices - 19% Pediatric Practices - 27% Reported doses administered Doses approved Public Information Goals Use risk communication best practices to ensure accurate, consistent, timely messages Acknowledge uncertainty Honest, open and transparent Many voices, one message Media Relations 43 press releases issued between April 29 and January 21 Weekly flu activity updates on website Number of Press calls Number of Briefings Dr. Daines radio and TV interviews Satellite media tours Media events Media Events H1N1 Preparedness Town Hall Meetings Buffalo, Rochester, Syracuse, Lake Placid, Westchester County, Long Island Dr. Daines flu shot H1N1 patient education pieces One-pager for pregnant women; Patient fact sheet for flu prevention; Patients fact sheet for home care; Fact sheets on antivirals; Fact sheet on H1N1 testing parameters.

Educational Materials Action steps for employers School Action Kit 2 new fact sheets 3 new posters Go to the Head of the Line bus card Pre-event materials updated Bus Poster Campaign Mass Media Campaign Radio ads "Peak Flu Season" "H1N1 Available to All" "Get a healthy start in 21" "Health Care Worker-Right Thing to Do "Pregnant Woman Why Wh I m Getting Vaccinated "Know what to do about the flu TV ads "Spread the Word, Not the Virus" "Your H1N1 vaccination protects us all "Stay healthy in the workplace" "Know what to do about the flu" New Media Twitter account Media outlets t among followers Facebook/spreadthewordnotthevirus About 3 fans to date YouTube posting for TV Public Service Announcements Lessons Learned -- Continuing Challenges For the next influenza pandemic: Manage expectations about vaccine supply; Improve vaccine manufacturing; Develop better triage mechanisms for sick persons. For seasonal influenza: Move to universal influenza vaccination; Increase health care system capacity to deliver routine immunizations. For overall public health preparedness Preserve the workforce, partnerships, etc. built during the pandemic response. 6