Dual Diagnosis Understanding the Unique Challenges Facing Children Suffering from Co-occurring Behavioral Health and Addiction Disorders



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Dual Diagnosis Understanding the Unique Challenges Facing Children Suffering from Co-occurring Behavioral Health and Addiction Disorders Randolph D. Muck, M.Ed. Advocates for Youth and Family Behavioral Health Treatment, LLC

We know the parents are really the problem!

Early Intervention and Prevention are Important because....

Link Between Perception and Use

Examples of Treating Adolescents with Co-occurring Disorders An integrated approach to treating issues Integrated Co-Occurring Treatment Model (ICT)-Ohio Dept. of MH, State and Center for Innovative Practices, child Guidance and Family Solutions Gender and Cultural Competence Voices, Stephanie Covington Continuing Care Assertive Continuing Care, Susan Godley, et al

0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100% Multiple Clinical Problems are the NORM! Alcohol 20% Cannabis Other drug disorder Depression 27% 33% 34% Anxiety 14% Trauma 24% ADHD 41% CD 48% Suicide Victimization 11% 63% Violence/ illegal activity 80% Source: CSAT 2009 Summary Analytic Data Set (n=20,826) 7

$0 $10,000 $20,000 $30,000 $40,000 $50,000 $60,000 $70,000 The Cost of Substance Abuse Treatment is Trivial Relative to the Costs Treatment Reduces SBIRT models popular due to ease of implementation and low cost Screening & Brief Inter.(1-2 days) Outpatient (18 weeks) In-prison Therap. Com. (28 weeks) Intensive Outpatient (12 weeks) Adolescent Outpatient (12 weeks) Treatment Drug Court (46 weeks) Methadone Maintenance (87 weeks) Residential (13 weeks) Therapeutic Community (33 weeks) $407 $1,132 $1,249 $1,384 $1,517 $2,486 $4,277 $10,228 $14,818 $750 per night in Medical Deto $1,115 per night in hospital $13,000 per week in intensive care for premature baby $27,000 per robbery $67,000 per assault $70,000/year $22,000 / year $30,000/ to keep a to incarcerate child-year in child in an adult foster care detention Source: French et al., 2008; Chandler et al., 2009; Capriccioso, 2004 in 2009

Investing in Substance Abuse Treatment Results in a Positive Return on Investment (ROI) Substance abuse treatment has an ROI of between $1.28 to $7.26 per dollar invested. Consequently, for every treatment dollar cut in the proposed budget, the actual costs to taxpayers will increase between $1.28 and $7.26. How will this happen? Individuals needing substance abuse treatment will not disappear but instead interface with much more expensive systems such as emergency rooms and prisons. Bottom line = The proposed $55 million dollar cut will cost Illinois taxpayers between $70 and $400 million within the next 1 to 2 years. Source: Bhati et al., (2008); Ettner et al., (2006)

Total days abstinent over 12 months at Month 12. Similarity of Clinical Outcomes : Cannabis Youth Treatment (CYT) Not significantly different by condition. 300 Trial 1 Trial 2 50% 280 260 240 But better than the average for OP in ATM (200 days of abstinence) 220 200 MET/ CBT5 (n=102) MET/ CBT12 FSN (n=102) MET/ CBT5 (n=99) ACRA (n=100) MDFT (n=99) Total Days Abstinent* 269 256 260 251 265 257 Percent in Recovery** 0.28 0.17 0.22 0.23 0.34 0.19 * n.s.d., effect size f=0.06 ** n.s.d., effect size f=0.12 * n.s.d., effect size f=0.06 ** n.s.d., effect size f=0.16 40% 30% 20% 10% 0% Percent in Recovery. Source: Dennis et al., 2004

Cost per day of abstinence over 12 months Moderate to large differences in Cost-Effectiveness by Condition Cost per person in recovery at month 12 $20 $16 MET/CBT5 and 12 did better than FSN Trial 1 Trial 2 ACRA did better than MET/CBT5, and both did better than MDFT $20,000 $16,000 $12 $8 $4 $0 MET/ CBT5 MET/ CBT12 FSN MET/ CBT5 ACRA MDFT CPDA* $4.91 $6.15 $15.13 $9.00 $6.62 $10.38 CPPR** $3,958 $7,377 $15,116 $6,611 $4,460 $11,775 * p<.05 effect size f=0.48 ** p<.05, effect size f=0.72 * p<.05 effect size f=0.22 ** p<.05, effect size f=0.78 $12,000 $8,000 $4,000 $0 Source: Dennis et al., 2004 Suggest the need to consider cost-effectiveness of treatment approaches

Average% Use Levels of Care TEDS-A 2009 Detox Residential IOP OP Natl 3.7 15.6 15.6 65.1 IN 0.0 2.0 1.0 98.8 Standardized screening/assessment, appropriate level of care, continuum of system better outcomes, fewer readmissions, cost savings

Cumulative Survival Substance Use Careers Last for Decades 1.0.9.8.7.6 Median of 27 years from first use to 1+ years abstinence.5.4.3.2.1 0.0 0 5 10 15 20 25 30 Years from first use to 1+ years abstinence Source: Dennis et al., 2005

Cumulative Survival Substance Use Careers are Shorter with Sooner Treatment 1.0.9.8 Year to 1 st Tx Groups.7.6 20+.5.4.3.2 10-19*.1 0.0 0 5 10 15 20 25 Years from first use to 1+ years abstinence Source: Dennis et al., 2005 30 0-9* * p<.05 (different from 20+)

Cumulative Survival Substance Use Careers are Longer the Younger the Age 1.0.9.8.7.6.5.4.3.2.1 0.0 0 of First Use 5 10 15 20 25 Years from first use to 1+ years abstinence Source: Dennis et al., 2005 30 Age of 1 st Use Groups under 15* 15-20* 21+ * p<.05 (different from 21+)

Interventions Associated With No or Minimal Change in Substance Use or Symptoms Passive referrals Educational units alone Probation services as usual Unstandardized outpatient services as usual Interventions associated with deterioration Treatment of adolescents with/in adult units

Do you know what happens in group treatment? Which EBP is this?

53% Have Unfavorable Discharges Total (61,153 discharges) LTR (5,476 discharges) STR (5,152 discharges) Detox (3,185 discharges) IOP (10,292 discharges) Outpatient (37,048 discharges) 0% 20% 40% 60% 80% 100% Completed Transferred ASA/ Drop out AD/Terminated Despite being widely recommended, only 10% step down after intensive treatment Source: Data received through August 4, 2004 from 23 States (CA, CO, GA, HI, IA, IL, KS, MA, MD, ME, MI, MN, MO, MT, NE, NJ, OH, OK, RI, SC, TX, UT, WY) as reported in Office of Applied Studies (OAS; 2005). Treatment Episode Data Set (TEDS): 2002. Discharges from Substance Abuse Treatment Services, DASIS Series: S-25, DHHS Publication No. (SMA) 04-3967, Rockville, MD: Substance Abuse and Mental Health Services Administration. Retrieved from http://wwwdasis.samhsa.gov/teds02/2002_teds_rpt_d.pdf.

25% 20% 15% 10% 5% 0% Substance Use Disorders are Common, US Treatment Participation Rates Are Low Few Get Treatment: 1 in 20 adolescents, 1 in 18 young adults, 1 in 11 adults 7.4% 20.1% Over 88% of adolescent and young adult treatment and over 50% of adult treatment is publicly funded 7.0% 0.4% 1.1% 0.6% 12 to 17 18 to 25 26 or older Abuse or Dependence in past year Treatment in past year Much of the private funding is limited to 30 days or less and authorized day by day or week by week Source: SAMHSA 2010. National Survey On Drug Use And Health, 2010 [Computer file]

% Any Contact 1% 1% 1% 10% 0% 1% 4% 8% 1% 3% 9% 15% 4% 5% 8% 11% 12% 13% 12% 23% 29% 35% 41% 49% 30% 41% 42% 46% 93% 97% 95% 95% Potential AOD Screening & Intervention Sites Adolescents (age 12-17) 100% 90% 80% 70% 60% 50% 40% 30% 20% 10% 0% No use in past year Less than weekly use Weekly Use Abuse or dependence Source: SAMHSA 2010. National Survey On Drug Use And Health, 2010 [Computer file]

Early Adolescent Treatment Work 1910 1920 1930 1940 1950 1960 1970 1980 1990 1996 Worth Street Narcotic Clinic in NY 743 youth Federal Narcotic Farms in Lexington, KY & Fort Worth, TX 22-440/yr Riverside Hospital in NYC 250 youth Teen Addiction Hospital Wards in several cities Drug Abuse Reporting Program (DARP)- 5,405 youth (587 followed) Treatment Outcome Prospective Study (TOPS)- 1042 youth (256 followed) Services Research Outcome Study (SROS) - 156 youth National Treatment Improvement Evaluation Study (NTIES) - 236 youth Drug Abuse Treatment Outcome Study of Adolescents (DATOS-A) - 3,382 youth (1,785 followed) Source: Dennis, M.L., Dawud-Noursi, S., Muck, R., & McDermeit, M. (2003)

The Current Renaissance of Adolescent Treatment Research Feature 1930-1997 1997-2012 Tx Studies* 17 Over 300 Random/Quasi 9 44 Tx Manuals* 0 30+ QA/Adherence Rare Common Std Assessment* Rare Common Participation Rates Under 50% Over 80% Follow-up Rates 40-50% 85-95% Methods Descriptive/Simple More Advanced Economic Some Cost Cost, CEA, BCA * Published and publicly available

Programs often LACK Evidenced Based Assessment to Identify and Practices to Treat: Substance use disorders (e.g., abuse, dependence, withdrawal), readiness for change, relapse potential and recovery environment Common mental health disorders (e.g., conduct, attention deficit-hyperactivity, depression, anxiety, trauma, self-mutilation and suicidal thoughts) Crime and violence (e.g., inter-personal violence, drug related crime, property crime, violent crime) HIV risk behaviors (needle use, sexual risk, victimization) Child maltreatment (physical, sexual, emotional) Recovery environment and peer risk

Assessment for ALL disorders is needed because... Having one disorder increases the risk of developing another disorder; The presence of a second disorder makes treatment of the first more complicated; Treating one disorder does NOT lead to effective management of the other(s); Treatment outcomes are poorer when cooccurring disorders are present.

Adolescents with SUD... (Meyers et al) Are largely undiagnosed Are distributed across diverse health & social service systems Have been adjudicated delinquent; Have histories of child abuse, neglect and sexual abuse; Have high co-morbidity with psychiatric conditions;

In practice we need a Continuum of Measurement (Common Measures) Screener Quick Comprehensive Special More Extensive / Longer/ Expensive Screening to Identify Who Needs to be Assessed (5-10 min) Focus on brevity, simplicity for administration & scoring Needs to be adequate for triage and referral GAIN Short Screener for SUD, MH & Crime ASSIST, AUDIT, CAGE, CRAFT, DAST, MAST for SUD SCL, HSCL, BSI, CANS for Mental Health LSI, MAYSI, YLS for Crime Quick Assessment for Targeted Referral (20-30 min) Assessment of who needs a feedback, brief intervention or referral for more specialized assessment or treatment Needs to be adequate for brief intervention GAIN Quick ADI, ASI, SASSI, T-ASI, MINI Comprehensive Biopsychosocial (1-2 hours) Used to identify common problems and how they are interrelated Needs to be adequate for diagnosis, treatment planning and placement of common problems GAIN Initial (Clinical Core and Full) CASI, A-CASI, MATE Specialized Assessment (additional time per area) Additional assessment by a specialist (e.g., psychiatrist, MD, nurse, spec ed) may be needed to rule out a diagnosis or develop a treatment plan or individual education plan CIDI, DISC, KSADS, PDI, SCAN

The New Age of Adolescent Services Pooled Data now < 25,000 Treatment of adolescents with adult models and/or mixed with adults does not work and is actually associated with drop out and increased use Need to modify models to be more developmentally appropriate for youth Need to assess and treat a wider range of problems including victimization, co-occurring mental health needs, and education needs Need to modify materials to be more concrete and use examples relevant to youth Don t stop asking questions!

Marijuana Use (Days of 90) Source: Funk, et al., 2003 Victimization and Level of Care Interact to Predict Outcomes 40 35 CHS Outpatient Traumatized groups have higher severity CHS Residential 30 25 20 15 10 5 0 High trauma group does not respond to OP Both groups respond to residential treatment Intake 6 Months Intake 6 Months OP -High OP - Low/Mod Resid-High Resid - Low/Mod.

Traumatic Victimization 40 90% have been victimized 20-25% report in past 90 days, concerns about reoccurrence Associated with higher rates of substance use HIV-risk behavior Co-occurring disorders

100% 90% 80% 70% 60% 50% 40% 30% 20% 10% 0% The Number of Major Clinical Problems is highly related to Victimization 15% 46% 71% Low (0) Moderate (1-3) High (4-15) Source: CSAT 2009 Summary Analytic Data Set (n=21,784) None One Two Three Four Five to Twelve Significantly more likely to have 5+ problems (OR=13.9) 30

Tanner-Smith, E.E., Wilson, S.J, & Lipsey, M.W. ( ). The comparative effectiveness of outpatient treatment for adolescent substance abuse: A metaanalysis. Journal of Substance Abuse Treatment, in press.

Interventions that Typically do Better than Practice in Reducing Recidivism (29% vs. 40%) Aggression Replacement Training Brief Strategic Family Therapy Reasoning & Rehabilitation Moral Reconation Therapy Thinking for a Change Interpersonal Social Problem Solving Multisystemic Therapy Functional Family Therapy Multidimensional Family Therapy Adolescent Community Reinforcement Approach MET/CBT combinations and Other manualized CBT NOTE: There is generally little or no differences in mean effect size between these brand names Source: Adapted from Lipsey et al 2001, Waldron et al, 2001, Dennis et al, 2004

The best is t have a stron program implemented well Implementation is Essential (Reduction in Recidivism) Thus one should optimally pick the strongest intervention that one can implement well Source: Adapted from Lipsey, 1997, 2005 The effect of a well implemented weak program is as big as a strong program implemented poorly 33

% Change: Abstinence at 6- months post-initial assessment *MET/ *ACRA/ **TARGET **SEE CBT 5 ACC YOUTH YOUTH 60.6 69.3 12.6 21.1 * GAIN Mandated ** GAIN Optional Source: SAIS System (GPRA)

36 Site Type IV Replication MET/CBT5 WA OR NV CA AK ID AZ UT MT WY CO NM ND MN SD WI NE IA IL KS MO OK AR TX MS LA MI IN KY TN AL NH VT ME NY MA RI PA CT OH NJ WV DE VA MD DC NC SC GA CYT: 4 Sites FL EAT: 36 Sites HI Source: Dennis, Ives, & Muck, 2008

Replication and Site Effects Treatment can vary by implementation within site/clinic We want to compare the range of implementation in practice with the clinical trials In order to compare sites, we will at both the central tendency (median) and distribution using a Tukey Box Plot like the one shown here. Middle 50% Range Median Criteria 3.00 2.50 2.00 1.50 1.00 0.50 0.00-0.50-1.00-1.50-2.00

Cohen s d Range of Effect Sizes (d) for Change in Days of Abstinence (intake to 12 months) by Site 1.40 1.20 1.00 EAT Programs did Better than CYT on average 6 programs completely above CYT 1.40 1.20 1.00 0.80 0.80 0.60 0.60 0.40 0.40 0.20 0.00 4 CYT Sites (f=0.39) (median within site d=0.29) Source: Dennis, Ives, & Muck, 2008 75% above CYT median 36 EAT Sites (f=0.21) (median within site d=0.49) 0.20 0.00

% Point Change in Abstinence Change in Abstinence by level of Quality Assurance: Adolescent Community Reinforcement Approach (A-CRA) 100% 90% 80% 70% 60% 50% 40% 30% 20% 10% 0% Effects associated with Coaching, Certification and Monitoring (OR=7.6) 4% Training Only 24% Training, Coaching, Certification, Monitoring Source: CSAT 2008 SA Dataset subset to 6 Month Follow up (n=1,961) 38

12 month recidivism To violent crime or arrest Crime/Violence and Substance Problems Interact to Predict Violent Crime or Arrest 100% Crime/ Violence predicted violent recidivism 80% 60% 40% Crime and Violence Scale Source: CYT & ATM Data Knowing both was the best predictor 20% 0% Substance Problem Scale (Intake) Substance Problem Severity did not predict violent recidivism

Overlap with Crime and Violence (cont.) Crime levels peak between ages of 15-20 (periods of increased stimulation and low impulse control in the brain) Adolescent crime is still the main predictor of adult crime

Treating Teens: A Guide to Adolescent Drug Programs http://drugstrategies.com/treatingteens.html

Co-occurring Mental Health Symptoms A Comparison of Nine Treatment Approaches Seven Challenges Chestnut Health Systems Adolescent Community Reinforcement Approach Multi-Systemic Therapy Multi-Dimensional Family Therapy Motivational Enhancement Therapy-Cognitive Behavioral Therapy 5 sessions Family Support Network 42

Change Effect Size d ((mean follow-up - mean intake)/ std dev. intake) -0.54-0.43-0.45-0.39-0.32-0.37-0.37-0.34-0.28-0.29-0.29-0.18-0.19-0.14-0.22-0.19-0.21-0.15-0.13-0.08-0.09-0.12-0.13-0.08-0.16-0.04-0.08 Change (post-pre) Effect Size for Emotional Problems by Type of Figure 8. Change (post-pre) Effect Size for Emotional Problems by Type Treatment of Evidenced Based Treatment 0.20 Seven Challenges (n=114) CHS Treatment (n=192) A-CRA- CYT/AAFT (n=2144) MST (n=85) MDFT (n=258) METCBT- CYT/EAT (n=5262) METCBT- Other (n=878) FSN (n=369) A-CRA- Other (n=276) 0.00-0.20-0.40-0.60 Four best on mental health outcomes include 7 challenges, CHS, A-CRA, & MST -0.80 Emotional Problem Scale Days of traumatic memories Days of victimization

Workforce Implications All programs reduced mental health / trauma problems with 4 doing particularly well: Seven Challenges, CHS, A-CRA, & MST A-CRA with a mix of BA/MA did as well as MST which targets MA level therapists and family therapists that are often in short supply Seven Challenges, with a mix of para-professional (nondegreed), BA/MA therapists did as well as A-CRA and MST While it is not the most effective, the shortest & least expensive (MET/CBT5) still has positive effects 44

Farm Party Anyone? Ever evolving Cyclical nature of use

What the Brain Science Presented Will Not Do Make you an expert in the science of the brain (or return to your brain everything you have forgotten since undergraduate school). Assist you in obtaining funding for PET/FA/fMRI or other technologies to screen all of your youth. Provide all of the information about the adolescent brain that is useful to know. Settle the argument: addiction is/is not a disease No quiz will follow the presentation.

Continuing Care The continuation of services in a seamless flow is imperative for successful client outcomes All too often, they fall through the cracks in the system = 14 days

100% 90% 80% 70% Do adolescents attend 12 step meetings after residential discharge? 85% 10 9 8 7 60% 6 50% 40% 42% 4.5 5 4 30% 3 20% 2 10% 1 0% Attended One or More Meetings Adults 0 Median No. Meetings Attended Adolescents 0

Assertive Continuing Care The Assertive Continuing Care Protocol (ACC) is a continuing care intervention specifically designed for adolescents following a period of residential treatment. ACC is delivered primarily through home visits. ACC case managers are assertive in their attempts to engage participants. Case managers deliver the Adolescent Community Reinforcement Approach (ACRA) procedures

100% Early (0-3 mon.) Abstinence Then Improves Sustained (4-9 mon.) Abstinence 90% 80% 70% 60% 50% 40% 30% 20% 10% 0% 69% 73% 59% 19% 22% 22% Any AOD (OR=11.16*) Alcohol (OR=5.47*) Marijuana (OR=11.15*) Early(0-3 mon.) Relapse Early (0-3 mon.) Abstainer * p<.05 Source: Godley et al 2002, 2007

Self-Management and Recovery Training: (SMART) Recovery Origins in Rational Emotive Therapy Portable, applicable in real world, online groups Group Modality Led by trained facilitators Open enrollment Uses common elements of CBT Considered easy to learn and use http://www.smartrecovery.org/intro/

Technological Approaches CONTINUING CARE/Ongoing Supportive Services University of Arizona pod casting, texting, geofencing 90 95% Engagement, Utilization, Satisfaction Recovery Services for Adolescents and their Families (RSAF) CSAT Research Project (Cell phone, Texting, Web Site, CRAFT for Parent Groups) Dick Dillon, St. Louis Second Life Continuing Care Participation Increased from 40% to 90% over 6 months

Summary Know what treatment services are provided (EBP?, Appropriate for identified problems?, Implemented with fidelity?) Understand brain science and addiction Ensure EBPs used that can be done well given limitations (staff experience/training, cost, belief in approach) Push for appropriate services and demand outcome data and ongoing CLINICAL SUPERVISION DO NOT Ignore Continuing Care/Supportive Services! =

Contact Information Randolph D. Muck, M.Ed. Senior Clinical Consultant Advocates for Youth and Family Behavioral Health Treatment, LLC e-mail: randy@ayftx.com Website: www.ayftx.com Phone: 240-397-3918

Normal Adolescent Development

Normal Adolescent Development Based on the stage of their brain development, adolescents are more likely to: act on impulse misread or misinterpret social cues and emotions get into accidents of all kinds get involved in fights engage in dangerous or risky behavior

Normal Adolescent Development Adolescents are less likely to: think before they act pause to consider the potential consequences of their actions modify their dangerous or inappropriate behaviors

Normal Adolescent Development Movement Towards Independence Struggle with sense of identity Feeling awkward or strange about one's self and one's body Focus on self, alternating between high expectations and poor self-esteem Interests and clothing style influenced by peer group Moodiness

Normal Adolescent Development Movement Towards Independence, Cont. Improved ability to use speech to express one's self Realization that parents are not perfect; identification of their faults Less overt affection shown to parents, with occasional rudeness Complaints that parents interfere with independence Tendency to return to childish behavior, particularly when stressed

Normal Adolescent Development Future Interests and Cognitive Changes Mostly interested in present, with limited thoughts of the future Intellectual interests expand and gain in importance Greater ability to do work (physical, mental, emotional)

Normal Adolescent Development Sexuality Display shyness, blushing, and modesty Girls develop physically sooner than boys Increased interest in sex Movement toward heterosexuality with fears of homosexuality Concerns regarding physical and sexual attractiveness to others Frequently changing relationships

Normal Adolescent Development Morals, Values, and Self-Direction Rule and limit testing Capacity for abstract thought Development of ideals and selection of role models More consistent evidence of conscience Experimentation with sex and drugs (cigarettes, alcohol, and marijuana)

Time for a Break Do I Want a Cookie or Cocaine?

Neuron to Neuron How Does the Brain Communicate? Neurotransmitters - The Brain's Chemical Messenger Receptors - The Brain's Chemical Receivers Transporters - The Brain's Chemical Recyclers

They had the audacity to hi-jack Christmas

Everyone who has watched futurama knows slugs will feed on your brain

Like falling in love for the fist time Drugs seem so sweet when you meet them hey her clip is pink, she doesn t want to hurt anyone

How did this happen? She was so good to me! The colors are pretty.

Right lateral and top views of the dynamic sequence of maturation over the cortical surface Gogtay N et al. PNAS 2004;101:8174-8179 2004 by National Academy of Sciences

Brain Activity on PET Scan After Cocaine Use Be VERY Careful with interpretation of data/ imaging studies!