ZENTIVA S HISTORY. Zentiva s transformation over time...

ZENTIVA S HISTORY Zentiva s transformation over time...

ZENTIVA HAS A LONG HISTORY OF PRODUCING HIGH QUALITY PHARMACEUTICALS. TODAY IT IS THE 3 RD LARGEST AND THE FASTEST GROWING GENERICS COMPANY IN EUROPE. ZENTIVA S TRANSFORMATION OVER TIME...

OUR MARKETS Z E N T I VA, L O C AT E D I N T H E H E A R T O F E U R O P E, C U R R E N T LY O P E R AT E S I N A N D R E A C H E S 3 2 M A R K E T S O U T T O A TA R G E T P O P U L AT I O N O F C L O S E T O 800 MILLION PEOPLE. ZEN T I VA S T R ANSFO R M AT I O N OV ER T I M E...

15 th century Zentiva s origins traced to the Black Eagle pharmacy in Prague THE ROOTS OF ZENTIVA GO BACK TO THE BLACK EAGLE PHARMACY, ONE OF THE OLDEST PHARMACIES IN BOHEMIA. 15 th century 1857 1930 1946 1993 1998 2000 2003 2004

1857 The Black Eagle pharmacy was purchased by the Fragner family IN 1857 THE PHARMACY WAS ACQUIRED BY THE FRAGNER FAMILY WHO BUILT A PHARMACEUTICAL PLANT OUTSIDE PRAGUE. THIS IS THE SITE OF ZENTIVAS CURRENT HEADQUARTERS AND PRODUCTION FACILITIES IN PRAGUE. FIRST OINTMENT 1866 Benjamin Fragner Karel Fragner 15 th century 1857 1930 1946 1993 1998 2000 2003 2004

1930 The Company s 1 st production in Prague THE COMPANY FIRST STARTED PRODUCTION AT A PLANT IN THE VILLAGE OF DOLNÍ MĔCHOLUPY, THE SITE OF ZENTIVA S CURRENT HEADQUARTERS AND PRODUCTION FACILITIES IN PRAGUE. 15 th century 1857 1930 1946 1993 1998 2000 2003 2004

1946 Zentiva is nationalised by the Czech government ZENTIVA WAS NATIONALISED BY THE CZECH GOVERNMENT IN 1946 AND THE PLANT AT DOLNÍ MĚCHOLUPY BECAME PART OF SPOFA (UNITED PHARMACEUTICAL WORKS) AND A LEADER IN PHARMACEUTICAL PRODUCTION IN CZECHOSLOVAKIA. THE BUSINESS HAD 750 EMPLOYEES. 15 th century 1857 1930 1946 1993 1998 2000 2003 2004

1993 IN 1993, ZENTIVA RECEIVED ITS 1 ST MANUFACTURING Léčiva the predecessor of Zentiva was formed PRACTICES CERTIFICATE UNDER THE WHO STANDARDS FOR THE PRODUCTION OF ANTIBIOTICS. ZENTIVA WAS THE 1 ST MANUFACTURING OPERATION IN THE CZECH REPUBLIC TO RECEIVE THE CERTIFICATE. LÉČIVA THE PREDECESSOR OF ZENTIVA 15 th century 1857 1930 1946 1993 1998 2000 2003 2004

1998 Management buyout of Zentiva. Company begins focus on branded generic medicines IN 1998, THE MANAGEMENT OF ZENTIVA TOGETHER WITH THE PRIVATE GROUP WARBURG PINCUS FUNDS ACQUIRED A MAJORITY SHAREHOLDING IN THE COMPANY. THIS STARTED A NEW PHASE IN THE COMPANY S DEVELOPMENT BASED ON A BRANDED GENERICS STRATEGY. INVESTMENTS WERE MADE IN STATE-OF-THE-ART FACILITIES AND R&D AS THE COMPANY STARTED TO INTRODUCE A PORTFOLIO OF MODERN BRANDED GENERIC MEDICINES. 15 th century 1857 1930 1946 1993 1998 2000 2003 2004

2000 Implementation of new business processes and structures IN 2000, ZENTIVA WAS DELISTED FROM THE PRAGUE STOCK EXCHANGE. 15 th century 1857 1930 1946 1993 1998 2000 2003 2004

2003 The acquisition of Slovakofarma led to the launch of the Zentiva corporate brand IN 2003, ZENTIVA BEGAN ITS EXPANSION INTO CENTRAL AND EASTERN EUROPE WHEN IT BOUGHT SLOVAKOFARMA, THE LEADING PHARMACEUTICAL COMPANY IN SLOVAKIA. 15 th century 1857 1930 1946 1993 1998 2000 2003 2004

2004 Zentiva was listed on the Prague and London Stock Exchanges ZENTIVA WAS LISTED ON THE PRAGUE AND LONDON STOCK EXCHANGES IN 2004. THIS WAS THE FIRST INITIAL PUBLIC OFFERING (IPO) ON THE PRAGUE STOCK EXCHANGE. FIRST IPO ON THE PRAGUE STOCK EXCHANGE 15 th century 1857 1930 1946 1993 1998 2000 2003 2004

2005 Zentiva continued its regional expansion into Romania IN 2005, ZENTIVA CONTINUED ITS REGIONAL EXPANSION WITH THE ACQUISITION OF SICOMED, THE LEADING GENERICS COMPANY IN ROMANIA. 2005 2006 2007 2009 2010 2011 2012 2013 2014 2015

2006 Sanofi became the largest shareholder in Zentiva IN 2006, SANOFI BECAME THE LARGEST SHAREHOLDER IN ZENTIVA WHEN IT TOOK A 24.9% STAKE IN THE COMPANY. 2005 2006 2007 2009 2010 2011 2012 2013 2014 2015

2007 Zentiva further extended its geographic reach into Turkey ZENTIVA ACQUIRED ECZACIBASI GENERIC PHARMACEUTICALS, A LEADING PHARMACEUTICAL COMPANY IN TURKEY. CONSEQUENTLY, ZENTIVA BECAME A LEADING GENERICS COMPANY IN CENTRAL AND EASTERN EUROPE. 2005 2006 2007 2009 2010 2011 2012 2013 2014 2015

2009 Zentiva became part of the Sanofi group ZENTIVA BECAME PART OF THE SANOFI GROUP AND AN IMPORTANT PART OF THE GROUP S STRATEGY TO BECOME A DIVERSIFIED GLOBAL HEALTHCARE COMPANY FOCUSED ON PATIENT S NEEDS. 2005 2006 2007 2009 2010 2011 2012 2013 2014 2015

2010 Zentiva acquired Inhaler franchise ZENTIVA ANNOUNCED ITS INTENTION TO ENTER THE RESPIRATORY MARKET. INHALER DEVELOPMENT CENTRE, GERMANY INHALER DEVICE 2005 2006 2007 2009 2010 2011 2012 2013 2014 2015

2011 The Zentiva brand is launched into Western European countries 2005 2006 2007 2009 2010 2011 2012 2013 2014 2015