Enzymes in Industrial Applications: Global Markets



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A BCC Research Biotechnology Report Applications: Global BIO030F Use this report to: Understand the global market for industrial enzymes as well as the comparative strengths and weaknesses of each enzyme and technology Validate marketing plans with this evaluation of future strategies within the industrial enzymes market, including market initiatives, setbacks, and demands Assess growing competition, and changing customer needs, patent expiries, new technologies, and other influences on market growth, and allocate marketing and R&D resources accordingly Maintain a competitive standing by learning about the acquisition strategies and collaborations of key companies. T: 866-285-7215, 1-781-489-7301 F: 781-489-7308 sales@bccresearch.com www.bccresearch.com

The global market for industrial enzymes is estimated at $3.3 billion in 2010. This market is expected to reach $4.4 billion by 2015, a compound annual growth rate (CAGR) of 6% over the 5-year forecast period. Introduction Enzyme technology is a subfield of biotechnology, and offers new processes to develop and manufacture bulk and high value-added products with the use of enzymes as biocatalysts. Enzymes are used to meet needs in industries, such as food and beverages, which include bread, cheese, beer, and vinegar; and fine chemicals, which include amino acids, vitamins, and pharmaceuticals. Enzymes are also used in cleaning and environmental processes, or for analytical and diagnostic purposes. Enzymes are proteins that catalyze chemical reactions. These biological catalysts lower the amount of activation energy needed and thus speed up the reaction. Enzyme or biological catalysts have the following characteristics. All enzymes are globular proteins. They can increase the rate of a reaction. Most enzymes act specifically with only one substrate to produce products. Enzymes are regulated from a state of low activity to high activity and vice versa. Enzymes are very sensitive to changes in ph, temperature, and the concentration of substrate. The presence of enzymes does not affect the nature of an end product Enzymes are obtained from plants, animal tissues, bacteria, fungi, and yeast. The bulk of enzymes are derived from microorganisms in submerged cultures in large reactors called fermentors. Plant derived commercial enzymes are proteolytic enzymes papain, bromelain, and ficin and some other specialty enzymes like lipoxygenase from soybeans. BCC Research report provides information about the biochemistry of small organisms that the specific enzymes are responsible for the production of brewing, baking, and milk and dairy products. This study also discusses the strength and weaknesses of each type of technology in light of the new technologies, growing competition, and changing customer needs. This report is useful to the manufacturers and users of food and beverages, animal feed, detergents, leather, and other technical enzyme. Chemical, biochemical and biotechnical companies industries, and research institutes will find this study to be of interest. The information for this report has been collected through both primary and secondary research methodologies by collecting the data through interviews and correspondence with various chemical, biotechnical, and food and beverage technical experts. A secondary source includes a comprehensive literature search, which included technical newsletters and journals, and many other sources. SUMMARY FIGURE GLOBAL INDUSTRIAL ENZYMES MARKET, 2008-2015 ($ MILLIONS) 2,000 1,500 $ Millions 1,000 500 0 2008 2009 2010 2015 Technical enzymes Food and beverage enzymes Others Source: BCC Research

Scope of Study Technical enzymes are valued at just over $1 billion in 2010. This sector will increase at a 6.6% compound annual growth rate (CAGR) to reach $1.5 billion in 2015. The highest sales of technical enzymes occurred in the leather market, followed by the bioethanol market. The scope of this report is broad and includes: Descriptions of various technical enzyme applications, including detergent, textile, pulp and paper, leather, and miscellaneous chemicals; also, food applications, including confectionery and sweeteners, dairy, fruit and vegetable processing, and animal feed Analysis of the current market status, with data from 2009, estimates for 2010, and projections of compound annual growth rates (CAGRs) through 2015 Evaluation of the industry on a global basis, from both marketing and application perspectives Discussion of emerging technologies with a thorough patent analysis Information about major companies and their contributions to the enzymes industry. Table of Contents Chapter One: Introduction Study Objectives Reasons for Doing This Study Intended Audience Scope of The Study Methodology Information Sources About The Author Related BCC Research Reports BCC Online Services Disclaimer Chapter Two: Executive Summary Executive Summary Summary Table Global Industrial Enzymes Market, Through Summary Figure Global Industrial Enzymes Market, 2008- Chapter Three: Overview Definitions Enzyme Coenzyme Prosthetic Group Active Site General Characteristics of Enzymes Chemical Nature of Enzymes Enzyme Nomenclature History of Enzymes Table 1 History of Enzymes Factors Affecting The Performance of Enzymes Temperature Ph Ions Concentration Mechanism of Enzyme Action Enzyme Specificity Production of Enzymes Table 2 Protein Engineered Commercial Enzymes Table 3 Examples of Genetically Engineered Enzymes Genetically Modified Organisms in Enzyme Manufacturing Table 4 Advantages and Disadvantages of Enzymes Chapter Four: Classification of Enzymes Classification Based On Structure and Parts Classification Based On Chemical Reaction The Enzymes Catalyze Oxidoreductases Transferases Hydrolases Lyases Isomerases Ligases Or Synthetases Table 5 Types of Enzymes and Reactions They Catalyze Classification of Enzymes Based On Their Application Table 6 Differences Between Industrial and Medical Enzymes Industrial Enzymes Advantages/Benefits of Industrial Enzymes Table 7 Commonly Used Industrial Enzymes Table 8 Commonly Used Enzymes in Detergents Enzymes in The Textile Industry Enzymes in The Pulp and Paper Industry Enzymes in The Leather Industry Table 9 Enzymes Used in Various Processes of Leather Manufacturing Enzymes in The Food and Beverage Industry Enzymes in The Starch and Sugar Industry Enzymes in The Baking Industry Table 10 Enzymes Used in The Baking Industry Enzymes in The Dairy Industry Enzymes in The Brewing Industry Enzymes in The Fruit Juice Industry Enzymes in The Tea and Coffee Industry Enzymes in The Alcohol Industry Enzymes in The Animal Feed Industry Table 11 Enzymes Used in Animal Feed Chapter Five: Regulatory Aspects Gras Notices Table 12 Gras Notices, 2006 2010 (July) New Therapeutic Enzyme Approvals Table 13 New Approvals for Therapeutic Enzymes Other Approvals Chapter Six: Industry Structure Manufacturers/Suppliers of Enzymes Table 14 Leading Manufacturers/suppliers of Table 15 Leading Manufacturers and Suppliers of Table 16 Leading Manufacturers and Suppliers of Food and Beverage Enzymes Table 17 Leading Manufacturers and Suppliers of Animal Feed Enzymes Market Shares of Industry Leaders

Table of Contents, continued The food and beverage enzymes segment is expected to reach about $1.3 billion by 2015, from a value of $975 million in 2010, rising at a compound annual growth rate (CAGR) of 5.1%. Within the food and beverage enzymes segment, the milk and dairy market had the highest sales, with $401.8 million in 2009. Table 18 Global Market Shares of Detergent Enzyme Figure 1 Global Market Shares of Detergent Enzyme Table 19 Global Market Shares of Technical Enzyme Figure 2 Global Market Shares of Technical Enzyme Food and Beverage Enzymes Table 20 Global Market Shares of Food and Beverage Enzyme Figure 3 Global Market Shares of Food and Beverage Enzyme Animal Feed Enzymes Table 21 Global Market Shares of Animal Feed Enzyme Figure 4 Global Market Shares of Animal Feed Enzyme New Developments Genencor Table 22 New Developments By Genencor Novozymes Table 23 New Developments By Novozymes AB Enzymes Table 24 New Developments By Ab Enzymes Verenium Corp. Table 25 New Developments By Ab Verenium Corp. Others Table 26 New Developments By Ab Verenium Corp. Chapter Seven: Market Analysis Table 27 Global Industrial Enzymes Market, Through Figure 5 Global Industrial Enzymes Market, 2008-2015 ($ Millions) Table 28 Differences Between Enzymatic and Nonenzymatic Detergents Table 29 Global Market for By Region, Through Figure 6 Global Market for By Region, 2008- Table 30 Global Market for By Region, Through Figure 7 Global Market for By Region, 2008- Food and Beverage Enzymes Table 31 Global Market for Food and Beverage Enzymes By Region Through Figure 8 Global Market for Food and Beverage Enzymes By Region, 2008- Animal Feed Table 32 Global Market for Feed Enzymes By Region, Through Figure 9 Global Market for Animal Feed Enzymes By Region, 2008- Global Regional Market Shares Table 33 Global Enzyme Market Shares By Region, 2009 (%) Figure 10 Global Enzyme Market Shares By Region, 2009 (%) Market By Application Applications for Applications for Textile Enzymes Table 34 Global Market for Textile Enzymes, Through Figure 11 Global Market for Textile Enzymes, Through Pulp and Paper Industry Table 35 Global Market for Pulp and Paper Enzymes, Through Figure 12 Global Market for Pulp and Paper Enzymes, Through Bioethanol Table 36 Global Market for Bioethanol Enzymes, Through Figure 13 Global Market for Bioethanol Enzymes, 2008- Leather Enzymes Table 37 Global Market for Leather Enzymes, Through Figure 14 Global Market for Leather Enzymes, 2008- Total s for Technical Enzymes By Application Table 38 Global Revenue for in Various Application Segments, Through 2015 ($ Millions) Figure 15 Global Revenues for in Various Application Segments, 2008- Enzymes in The Food Industry Sugar Syrups Or Sweeteners Table 39 Global Market for Enzymes in Sugar Syrups and Sweetners, Through Figure 16 Global Market for Enzymes in Sugar Syrups and Sweetners, 2008- Baking Industry Table 40 Global Market for Enzymes in The Baking Segment, Through Figure 17 Global Market for Enzymes in The Baking Segment, 2008- Brewing Enzymes Table 41 Global Market for Enzymes in The Brewing Segment, Through Figure 18 Global Market for Enzymes in Brewing Segment, 2008- Milk and Dairy Enzymes Table 42 Global Market for Enzymes in The Milk and Dairy Segment, Through Figure 19 Global Market for Enzymes in The Milk and Dairy Segment, 2008- Beverages Table 43 Global Market for Enzymes in The Beverage Segment, Through Figure 20 Global Market for Enzymes in The Beverage Segment, 2008- Others Table 44 Global Market for Enzymes in The Others Category, Through Figure 21 Global Market for Enzymes in The Others Category, 2008-

Table of Contents, continued Total for Food and Beverage Enzymes By Application Table 45 Global Revenue for Food and Beverage Enzymes in Various Application Segments, Through Figure 22 Global Revenue for Food and Beverage Enzymes in Various Application Segments, 2008-2015 ($ Millions) Animal Feed Enzymes Market Shares of Applications Table 46 Global By Application, 2009 (%) Figure 23 Global Technical Enzyme Market Shares, By Application, 2009 (%) Market Shares of Food and Beverage Enzymes Applications Table 47 Global Food and Beverage Enzymes By Application, 2009 (%) Figure 24 Global Food and Beverage Enzymes Market Shares, By Application, 2009 (%) Chapter Eight: Patent Analysis Patents By Year Table 48 U.S. Patents On Industrial Enzymes By Year, Figure 25 U.S. Patents On Industrial Enzymes By Year, Figure 26 Number of Patents By Year, 2006 2010 (%) Patents By Type Table 49 U.S. Patents On Industrial Enzymes By Type, Figure 27 U.S. Patents On Industrial Enzymes By Type, Patents By Application Table 50 U.S. Patents On By Application, Figure 28 U.S. Patents On By Application, 2006 2010 (No.) Table 51 U.S. Patents On Food and Beverage Enzymes By Application, Figure 29 U.S. Patents On Food and Beverage Enzymes By Application, Patents By Company Table 52 U.S. Patents On Industrial Enzymes By Company, Figure 30 U.S. Patents On Industrial Enzymes By Company, Patents By Country Table 53 U.S. Patents On Industrial Enzymes By Country, Figure 31 U.S. Patents On Industrial Enzymes By Country, Table 54 Patent Shares of Industrial Enzymes By Country, 2006 To September 2010 (Number/%) Figure 32 U.S. Patent Shares of Industrial Enzymes By Country, 2006 To September 2010 (%) Patents By Assignee Table 55 U.S. Patents On Industrial Enzymes By Assignee Type, Figure 33 U.S. Patents On Industrial Enzymes By Assignee, Chapter Nine: Current Situation Factors Affecting The Industrial Enzymes Market Environmental Concerns Cost Reduction Innovative Use of Enzymes Continued Research and Development Significant Funding for Research On Bioethanol Production Advantageous Profile of Enzymes Manufacturers Strategies Future of The Industrial Enzymes Market Chapter Ten: Company Profiles Ab Enzymes Advanced Enzyme Technologies, Ltd. Amano Enzyme, Inc. Aum Enzymes Basf Corp. Biocatalysts, Ltd. Bioresource International, Inc. Cargill Texturizing Solutions Chr. Hansen Danisco A/s Direvo Industrial Biotechnology Gmbh Dsm Food Specialties Dyadic International Enzymatic Deinking Technologies, Llc Enzyme Solutions, Inc. Hayashibara International Maps Enzymes, Ltd. Novozymes A/s Specialty Enzymes & Biotechnologies Co. Verenium Corp. Appendix: Abbreviations 139 pages 55 tables

Related Reports Enzymes for Industrial Applications ID: BIO030E Published: 01/08 Enzyme Inhibitors with Broad Therapeutic Applications ID: BIO057A Published: 06/06 Environmental for Biotechnology ID: BIO019B Published: 01/08 About BCC Research BCC Research is a leading publisher of high-quality, technology market research reports and technical publications. BCC Research reports provide quantified measurements of the market and all major industry segments, as well as in-depth analysis of key market drivers and trends. BCC Subscriptions Access hundreds of published reports and automatically receive newly published research with a BCC Report Subscription. We can tailor a complete package of material that meets your needs and budget. BCC Custom Research Improve your strategic planning efforts with a BCC custom research study. We will work with you to determine what information is needed and deliver specific qualitative and quantitative analysis that supports your business objectives. Call 866-285-7215 or 1-781-489-7301 (intl), or e-mail sales@bccresearch.com for more information about any of BCC Research s products and services.