Root cause analysis in context of WHO International Classification for Patient Safety

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1 NHS Presentation to [XXXX Company] [Type Date] Root cause analysis in context of WHO International Classification for Patient Safety Dr David Cousins Associate Director Safe Medication Practice and Medical Devices

How heath care provider organisations manage patient safety incidents Healthcare professional Incident Patient/Carer External organisation or agency Incident report Complaint Department of Health Regulators Request additional information Feed back Risk/complaint manager Local analysis and learning External report Request additional information Health & Safety Healthcare commissioners and purchasers Industry

Why RCA? Root Cause Analysis (RCA) To identify the root causes and key learning from serious incidents and use this information to significantly reduce the likelihood of future harm to patients Objectives To establish the facts i.e. what happened (effect), to whom, when, where, how and why To establish whether failings occurred in care or treatment To look for improvements rather than to apportion blame To establish how recurrence may be reduced or eliminated To formulate recommendations and an action plan To provide a report and record of the investigation process & outcome To provide a means of sharing learning from the incident To identify routes of sharing learning from the incident

Basic elements of RCA WHAT happened HOW it happened WHY it happened Unsafe Acts Human Behaviour Contributory Factors Direct Care Delivery Problems unsafe acts or omissions by staff Service Delivery Problems unsafe systems, procedures environment, healthcare products including medicines and devices ) Solution Development & Feedback

Human factors (Ergonomics) those elements that influence the performance of people operating equipment or systems; they include behavioural, medical, operational, task-load, machine interface and work environment factors the environmental, organisational, job factors, human and individual characteristics which influence behaviour at work

RCA teams in healthcare RCA undertaken in the healthcare setting by healthcare staff familiar with the treatments and setting Multidisciplinary group of 3-4 persons One of which should be fully trained in incident investigation and analysis Objective attitude Good organisational skills Use of experts

Pre-investigation risk assessment A Potential Severity (1-5) B Likelihood of recurrence at that severity (1-5) C Risk Rating (C = A x B) Post-investigation risk assessment A Potential Severity (1-5) B Likelihood of recurrence at that severity (1-5) C Risk Rating (C = A x B)

FP7 www.who.int/patientsafety/implementation/taxonomy

The conceptual framework for ICPS The conceptual framework for the ICPS was designed to provide a much needed method of organising patient safety data and information so that it can be aggregated and analyzed to: Compare patient safety data across disciplines, between organisations, and across time and borders; Examine the roles of system and human factors in patient safety; Identify potential patient safety issues; and Develop priorities and safety solutions. Donaldson L et al. In J Qual Health Care 2009; 21: many articles

ICPS Drafting Principles The classification be based upon concepts as opposed to terms or labels; The language used for the definitions of the concepts be culturally and linguistically appropriate; The concepts be organised into meaningful and useful categories; The categories be applicable to the full spectrum of healthcare settings in developing, transitional and developed countries; The classification be complementary to the WHO Family of International Classifications; The existing patient safety classifications be used as the basis for developing the international classification s conceptual framework; and The conceptual framework be a genuine convergence of international perceptions of the main issues related to patient safety. Donaldson L et al. In J Qual Health Care 2009; 21:

ICPS Patient safety incident - definition Patient safety incident: an event or circumstance which could have resulted, or did result, in unnecessary harm to a patient The use of the term unnecessary in this definition recognizes that errors, violations, patient abuse and deliberately unsafe acts occur in healthcare and are unnecessary incidents, whereas certain forms of harm, such as an incision for a laparotomy, are necessary. The former are incidents, whereas the latter is not. Runciman W et al. International Journal for Quality in Health Care 2009; Volume 21, Number 1: pp. 18 26

ICPS Model

ICPS medicines data fields (examples) 1) Medication incident/error 2) Medicines process (ordinal data) Prescribing Dispensing/preparation Administration Monitoring 3) Type of medicines errors Wrong patient Wrong medicine Wrong formulation Wrong dose Wrong frequency Wrong quantity Wrong rate of administration Known medicine allergy Known clinical contraindication Expired medicine Wrong storage Omitted and delayed medicine

ICPS data fields - general Detection Error recognition Change in patients status By machine/environmental change/ alarm By count/audit/review Pro-active risk assessment Contributing factors/targets for actions Patient factors Staff factors Work/environmental factors Organisational / service factors External factors Other Staff and patient factors Cognitive Performance Behaviour Communication Pathophysiological/disease related Emotional Social factors Work and environmental factors Physical environment / infrastructure Remote / long distance from service Environmental risk assessment / safety evaluation Current code specifications/regulation Organisational and service factors Protocols/policies/procedures/process Organisational decisions/culture Organisation of teams Resources/workload External factors Natural environment Products, technology and infrastructure Services, systems and policies Mitigating factors Directed to patient Directed to staff Directed to organisation Directed to an agent Other Ameliating actions Patient related Organisation related Actions to reduce risk Patient outcome Type of harm Degree of harm Social / economic impact Organisational outcomes Media management / public relations Claims/risk management Local notification and resolution Complaint management Stress debriefing/staff counselling Reconciliation/mediation

Comparing Terminology 1 WHO Patient safety Terms MedDRA terms v 15.1 WHO-ART terms Prescribing LLT Drug prescribing error DRUG PRESCRIBING ERROR No such term LLT Intercepted prescribing error No such term Preparation/dispensing LLT Drug dispensing error No such term No such term LLT Intercepted drug dispensing error No such term Presentation/packaging HLT Product packaging issue No such term Delivery No such term No such term Administration LLT Drug administration error DRUG ADMINISTRATION ERROR No such term LLT Intercepted drug administration error No such term Supply/ordering No such term No such term Storage LLT Incorrect product storage No such term Monitoring HLT Medication monitoring errors No such term Essential term required Essential term present Non-essential term New term for WHO patient safety taxonomy

Comparing Comparing Terminology Terminology 2 1 WHO Patient safety Terms MedDRA terms v 15.1 WHO-ART terms Wrong patient LLT Wrong patient received medication No such term Wrong drug LLT Wrong drug administered Incorrect drug administered Wrong dose, strength, frequency LLT Incorrect dose administered Incorrect dose administered No such term LLT Underdose No such term No such term LLT Inappropriate schedule of drug Inappropriate schedule of drug administration administration No such term LLT Accidental overdose Accidental overdose No such term LLT Intentional overdose Intentional overdose No such term LLT Multiple drug overdose No such term No such term LLT Multiple drug overdose-accidental No such term No such term LLT Multiple drug overdose-intentional No such term No such term LLT Overdose No such term Wrong formulation or presentation LLT Product formulation issue No such term Wrong route LLT Incorrect route of drug administration Incorrect drug administration route No such term LLT Drug administered at inappropriate site Incorrect drug administration site No such term LLT Vaccine administered at inappropriate site No such term Essential term required Essential term present Non-essential term New term for WHO patient safety taxonomy

Comparing Terminology 3 WHO Patient safety Terms MedDRA terms v 15.1 WHO-ART terms Wrong quantity No such term No such term Wrong dispensing label instruction LLT Wrong directions typed on label No such term Contra-indicated LLT Medical treatment contraindicated No such term No such term LLT Documented hypersensitivity to administered drug No such term No such term LLT Labelled drug disease interaction No such term No such term LLT Labelled drug-drug interaction No such term No such term LLT Labelled drug-food interaction No such term Wrong storage LLT Incorrect product storage No such term Omitted medicine or dose LLT Drug dose omission No such term Expired medicine LLT Expired drug administered Expired medicine used Adverse drug reaction Detailed ADR terminology available Detailed ADR terminology available Essential term required Essential term present Non-essential term New term for WHO patient safety taxonomy

WHO project on vaccine labelling

Medication error reports involving vaccines reported to the National Reporting and Learning System in the UK January 2005 - December 20011. Types of error

21 Medication errors involving vaccines reported to WHO Vigibase by Pharmacovigilance Centres worldwide inception December 2012

The value of incident reports with low harm or no harm outcomes? Death Severe harm Moderate harm Low harm No harm

BNF dose information for phenytoin inj

Use of RCA and the EU Pharmacovigilance system Broader view of patient safety Not just product focused Greater understanding of systems of use and human factors Broader and new categories and methods for reporting and learning New methods to identify, communicate risks and solutions and implement and sustain safer practice