Curriculum vitae Corné M.J. Pieterse May 2016

Curriculum vitae Corné M.J. Pieterse May 2016 TABLE OF CONTENTS Personal details... 2 Education/ Qualifications... 2 Education... 2 Professional History... 2 Other Appointments and Affiliations... 3 Teaching... 5 Bachelor curriculum Biological Sciences... 5 Master curriculum Environmental Biology... 5 PhD programme Environmental Biology... 5 Description of research... 6 Scientific career... 6 Research impact... 6 Future research... 7 Research group, embedding and collaborations... 8 Plant-Microbe Interactions research group... 8 Local infrastructure... 8 Long-term collaborations... 8 Supervision and training activities... 10 MSc students... 10 PhD students... 10 Publications... 13 Peer-reviewed publications... 14 Contributions to books and proceedings... 20 Patent applications... 23 Abstracts for international meetings... 23 Invited lectures... 23 Acquisition of funding... 29 Relevant websites... 30 1/31

PERSONAL DETAILS Name: Prof.dr.ir. Corné M.J. Pieterse Date of Birth: 11 February 1964 Home address: Brugakker 67-10, 3704 RP Zeist, the Netherlands Nationality: Netherlands Current positions: Professor Plant-Microbe Interactions Director Institute of Environmental Biology Work address: Plant-Microbe Interactions, Department of Biology, Faculty of Science, Utrecht University, Padualaan 8, 3584 CH Utrecht, the Netherlands E-mail: C.M.J.Pieterse@uu.nl Phone: +31-30-253-6887 (work); +31-6-1547-1826 (mobile) Web: http://www.uu.nl/en/research/plant-microbe-interactions Personal page: http://www.uu.nl/staff/cmjpieterse Publications: Downloadable via http://www.uu.nl/en/research/plant-microbe-interactions Peer reviewed: 122, Non reviewed: 48, Patent applications: 2 Citations: Web of Science: 13.183 cites, h-index 53; Google Scholar: 21.352 cites, h-index 60 ResearcherID: http://www.researcherid.com/rid/a-9326-2011 ORCID ID: http://orcid.org/0000-0002-5473-4646 EDUCATION/ QUALIFICATIONS Education 1988: Doctoral (MSc) Plant Breeding and Plant Molecular Biology, Wageningen Agricultural University, the Netherlands (cum laude; top 5%). 1993: PhD degree, dissertation entitled "Differential gene expression in Phytophthora infestans during pathogensis on potato. Advisors Prof.dr.ir Pierre de Wit and Prof.dr.ir Francine Govers, Laboratory of Phytopathology, Wageningen Agricultural University, the Netherlands. Professional History 1988: Visiting Researcher - Laboratory of Prof. Natasha Raikhel, Plant Research Laboratory, Michigan State Univeristy, East Lansing, USA. 1989: PhD Student - Laboratory of Phytopathology, Wageningen Agricultural University, NL. 1993: Postdoc - Lab of Prof. L.C. van Loon, Phytopathology, Faculty of Biology, Utrecht University. 1998: Assistant Professor Molecular Phytopathology, Faculty of Biology, Utrecht University. 2004: Awarded VICI fellowship for innovative research by Dutch Science Foundation (1.25 M ). 2004>: Professor and Head of the Plant-Microbe Interactions group, Department of Biology, Faculty of Science, Utrecht University. 2009>: Scientific Director Institute of Environmental Biology, Faculty of Science, Utrecht University. 2010: Awarded ERC Advanced Investigator Grant (2.5 M ). 2013: Elected member of the Royal Netherlands Academy of Arts and Sciences (KNAW). 2014>: Secretary of the Section Biology of the KNAW. 2014>: ISI Thompson Reuter Highly Cited Researcher. 2015>: ISI Thompson Reuter Highly Cited Researcher. 2015>: Distinguished Professor Faculty of Science, Utrecht University. 2/31

Other Appointments and Affiliations Utrecht University: 2014>: Member Adviescommissie Integriteitsbeleid Faculty of Science. 2014>: Member board UU focus area Future Food Utrecht. 2011>: Member Onderzoekadviesraad Faculty of Science. 2011: Coordinator of the audit of the research of the Department of Biology, period 2004-2010. 2009>: Member of the Executive Board of the Board of Studies of the Graduate School of Life Sciences. 2009-2015: Programme leader PhD programme Environmental Biology (>60 PhD students). 2005-2015: Programme leader MSc programme Environmental Biology (>150 MSc students). 2007>: Member Executive Board of the Board of Studies of the Graduate School of Life Sciences. 2007-2012: Member of the Board of Examiners of the Graduate School of Life Sciences. 2004-2012: Member/Chairman of committees for evaluation/coaching of high-potential applicants from the UU for VICI/VIDI innovative research fellowships (0.8-1.5 M ). 2009>: Member/chairman of committees for installation/evaluation of (personal) Chairs in: Behavioural Ecology, UU (chairman), Ecology and Biodiversity, UU (chairman), Mycorrhizal Ecology, UU (chairman), Microbial Ecology of Wetlands, UU (chairman), Duurzaam Bosbeheer, UU (chairman), Biomarine Sciences, UU (member), Fungal Biodiversity, UU (member), Molecular Physiology of Rice, UU (chairman), Fungal Molecular Physiology, UU (chairman), Bioinformatics, UU (chairman), Aquatic Ecology, UU (chairman), Plant Photobioloty, UU (chairman), Phytopathology, WUR (member), Ecological Virology, WUR (member), Tropical Phytopathology, WUR (member) 2009: Chairman Committee MSc Curriculum Biological Sciences. 2001-2003: Member of the Ba/Ma Committee installed to implement the Ba/Ma system in the Biological Sciences curriculum as proposed in the Bologna Accords of 1999. National: 2016: Selection committie VICI fellowships NWO. 2015: KNAW projectgroup Science & Media 2014>: Wetenschapscommissie Centraalbureau voor Schimmelcultures (KNAW-CBS) 2014: Jury KNAW onderwijsprijs 2014 profiel Natuur en Gezondheid. 2014>: Secretary KNAW Section Biology 2013: Member selection committee NWO MSc Talent Programme of the Graduate School Experimental Plant Sciences. 2011: Member selection committee NWO MSc Talent Programme of the Graduate School Experimental Plant Sciences. 2010>: Member of the Board of the Platform Experimental Plant Sciences of the Netherlands Organization of Scientific Research (NWO), co-organizer of yearly Lunteren meeting. 2009-2015: Member of the Board of the Platform Molecular Genetics of the Netherlands Organization of Scientific Research (NWO), co-organizer of yearly Lunteren meeting. 2007>: Member of the Research Committee of the national Graduate School Experimental Plant Sciences (>200 PhD students). 2007-2015: National coordinator of research theme Interactions between plants and biotic agents of the Graduate School Experimental Plant Sciences (with Prof. Marcel Dicke, Wageningen University). 2003-2007: Member Education Committee of the national Graduate School Experimental Plant Sciences. 3/31

2004-2007: Member Subcommittee Agriculture of the COGEM (Committee Genetic Modification; provides scientific advice to the Dutch government on risks of genetic modification and GMOs). 2007-2010: Member of the national Top Institute Pharma (TI-Pharma). 2003-2013: Member of the national Centre for BioSystems Genomics (CBSG). 2001-2008: Board member Section Phytopathology of the Royal Dutch Botanical Society (KNBV). 1992>: Member Royal Dutch Society of Phytopathologists (KNPV). Multiple dates: Panel member/chairman for review of grant proposals Netherlands Organisation for Scientific Research (NWO), Technology Foundation (STW), Centre for BioSystems Genomics, and the Graduate School of Experimental Plant Sciences. International: 2016: CSIRO Distinguished Visiting Research Fellow, Brisbane Australia. 2015>: Scientific Advisory Board Viikki Plant Science Centre (ViPS), Helsinki, Finland. 2014-2016: Secretary of the Board of Directors of the International Society of Molecular Plant-Microbe Interactions. 2014>: Editorial Board Member Current Plant Biology. 2013>: Editorial Board Member Oecologia. 2012>: Elected member of the Board of Directors of the International Society of Molecular Plant- Microbe Interactions. 2012-2015: International Advisory Board European Centre for Excellence in Environmental Adaptation, Estonia. 2013: Editor Topic Frontiers in Plant Science on Induced Plant Responses to Pathogens and Insects. 2011>: Associate Editor: Frontiers in Plant-Microbe Interactions. 2010-2012: Associate Editor Plant Physiology. 2007-2012: Monitoring Editor Plant Physiology. 1999-2012: Associate Editor European Journal of Plant Pathology. 2002-2012: Section Editor Plant Biology. 2007>: Editorial Board Member Journal of Chemical Ecology. 2008>: Editorial Board Member Communicative and Integrative Biology. 2002>: Editorial Board Member Journal of Food, Agriculture and Environment. 2007>: Member American Society of Plant Biologists (ASPB). 1990>: Member International Society for Molecular Plant-Microbe Interactions (IS-MPMI). 2016: International Advisory Board International Conference on Molecular Plant-Microbe Interactions, Portland, USA. 2015: Co-organizer of the International Symposium on PR-Proteins and Induced Resistance against Pathogens and Insects, Aachen, Germany (120 participants). 2014: International Advisory Board International Conference on Molecular Plant-Microbe Interactions, Rhodes, Greece. 2011: Co-organizer of the International Symposium on PR-Proteins and Induced Resistance against Pathogens and Insects, Neuchatel, Switzerland (160 participants). 2007: Organizer of the International Symposium on PR-Proteins and Induced Resistance against Pathogens and Insects, Doorn, the Netherlands (160 participants). Multiple dates: Organizer of the bi-annual International PhD Summerschool Environmental signaling: Arabidopsis as a model (2001-2015; 75-100 participants). Multiple dates: Review Panel Member for European Research Council (ERC), United States National Science Foundation (NSF), United States Department of Agriculture (USDA), United States- Israel Binational Science Foundation (US-IBSF), Swiss National Science Foundation (SNSF), Biotechnology and Biological Sciences Research Council (BBSRC, UK), Flanders Research Foundation (FWO, Belgium), Research Organization Catholic University Leuven (Belgium), Deutsche Forschungsgemeinschaft (DFG, Germany), Marsden Fund Council (New Zealand), and others. Multiple dates: Manuscript reviewer for Nature journals, Science journals, PNAS, Cell, Current Opinion in Plant Biology, Trends in Plant Science, Plant Cell, Plant Journal, Plant Physiology, New Phytologist, Plant Molecular Biology, Planta, Molecular Plant-Microbe Interactions, Molecular Plant Pathology, PLoS Pathogens, PLoS ONE, PLoS Biology, Phytopathology, European 4/31

Journal of Plant Pathology, Molecular Ecology, Proteomics, BMC Plant Biology, Plant and Soil, Plant Cell and Environment, Physiological and Molecular Plant Pathology, Euphytica, FEBS Letters, Current Genetics, Biological Control, Journal of Phytopathology, Heredity, Functional Plant Biology, Archives of Microbiology, Biocontrol Science and Technology, and Bioinformatics. Multiple dates: External evaluator for promotion (tenure track or full professor): Boyce Thompson Institute, Ithaca, USA; John Innes Centre, Norwich, UK; Humboldt University Berlin, Germany; University of Queensland, Brisbane, Australia; University of Minnesota, St. Paul, USA; University of Britisch Columbia, Vancouver, Canada; Australian Common Wealth Scientific and Research Organization (CSIRO), Australia; University of Gottingen, Germany; University of Lausanne, Switzerland; Virginia Tech College of Science, USA; University of Johannesburg, South Africa; Free University of Amsterdam; University of Amsterdam; Wageningen University; Leiden University. TEACHING Bachelor curriculum Biological Sciences, Utrecht University: The Experiment: practical course on experimental cycle for 40-60 1 st -year students (1994 2000) Cell Biology/Molecular Biology: tutorial for 30 1 st year students (1996 2004) Soil Ecology: lectures and practicals for 30-50 2 nd - year students (1995 2005) Plant-Microbe Interactions: lectures and practicals for 30 2 nd -year students (2006 2010) Microbial Interactions: lectures and practicals for 40-60 2 nd -year students (2011 present) Phytopathology (coordinator): lectures and practicals for 20-30 3 rd year students (1996 2005) Plants, Adaptation & Defense (coordinator with Dr. Pierik): lectures and practicals for 40-60 3 rd -year students (2006 present) Bachelor Thesis: 4-6 3 rd -year students per year (2005 present) Master curriculum Environmental Biology Graduate School of Life Sciences, Utrecht University Programme leader of the Master s programme Environmental Biology (with 5 tracks: Plant Biology, Fungal Biology, Ecology & Natural Resource Management, Behavioural Ecology, Biomarine Sciences & Palaeoecology) in which 9 Chair groups of the Department of Biology, Chemistry, Geosciences and Veterinary Sciences participate (2005-2015). In the past years, this MSc programme managed to attract a strongly increasing number of students, i.e. 25 in 2007/2008, 39 in 2008/2009, 65 in 2009/2010, 75 in 2010/2011, 70 in 2011/2012, 60 in 2012/2013, 70 in 2013/2014, 50 in 2014/2015, 65 in 2015/2016. Coordinator of the track Plant Biology of the MSc programme Environmental Biology: 10-15 students/year (2005-2011). Plants in Their Environment: theoretical MSc course for 10-15 students/2 years (2004-present). Molecular Plant Physiology & Biotechnology: MSc course for 10-15 students/2 years (2004-2011) Master Thesis: supervisor of 2-4 MSc students per year (2004-present). PhD programmes Environmental Biology (Utrecht) and Experimental Plant Sciences (national) Coordinator and co-organizer of the International PhD Summerschool Environmental signalling: Arabidopsis as a model on average 70-100 PhD students from all over the world participate in this course (biannually since 2001). The Summerschool consists of a mix of lectures by the international leaders in the field of plant biological research and PhD students. The programme typically consists of hot and emerging topics in plant biological research (2001-present). 5/31

DESCRIPTION OF RESEARCH Scientific career After completing my PhD research in 1993 on pathogenicity genes of the potato late blight pathogen Phytophthora infestans, I became intrigued by the way beneficial soil-borne microbes protect above-ground plant tissues against attack by pathogens and insect herbivores. During the early 90s, beneficial plant growth-promoting rhizobacteria selected from disease-suppressive soils were identified as potent activators of the plant immune system. However, the mechanism by which these beneficial microbes immunized plants was completely obscure and a major challenge in plant immunity research. In the course of my career I exploited Arabidopsis thaliana, the most sophisticated experimental system for plant biological research, to explore the plant immune system during interactions with beneficial microbes, pathogens, and insects. As a postdoc, I performed pioneering research on induced systemic resistance (ISR), a broad-spectrum plant immune response that is activated by beneficial rhizobacteria that live on plant roots. We uncovered a novel plant immunity signal transduction pathway and identified the hormones jasmonic acid and ethylene as key immune regulators of ISR a discovery which is highly cited and broadly recognized as fundamental in many plant immune responses triggered by beneficial microbes. After my appointment as assistant professor (1998), my group discovered that plant immunization by beneficials is based on priming for enhanced defense. Priming is a process in which immunized plants become potentiated to mobilize infection-induced defense responses faster and stronger after pathogen or insect attack, resulting in an enhanced level of protection. Besides our core discoveries on molecular mechanisms of priming, which greatly shaped the priming concept, we were the first to demonstrate that priming provides important fitness benefits - a discovery that presented a promising general concept for translation to crop plants (patent Defense priming in plants ). Because priming is also implicated in adaption of plants to abiotic stress, the priming concept has spread widely through the biology community. In recent years, new genomics technology greatly advanced plant research and created break-through opportunities to investigate the plant immune response at a high level of complexity. In natural ecosystems and under agricultural field conditions, plants are members of complex communities and interact with multiple organisms. Upon my appointment as full professor (2004), I expanded my research to address a challenging new question: how do plants integrate signals induced by beneficial microbes, pathogens, and insects into the most appropriate adaptive response? With Prof. Marcel Dicke (Wageningen University), I brought together the worldwide largely separated fields of phytopathology and entomology. This resulted in important novel insights into the complexity of the plant immune signaling network that has evolved during the arms races between plants, microbes and insects. My group was the first to demonstrate that the key defense regulator NPR1 is crucial in coordinating the interplay between different hormone-regulated immune responses. Moreover, our in-depth analysis of crosstalk between defense signaling pathways shaped the notion that plants use this powerful regulatory network to finely tailor their immune response to the attackers that they are encountering. Intriguingly, recent discoveries demonstrate that specialized attackers hijack hormone-regulated defenses to suppress host immunity. Hence, uncovering the complexity of the plant defense signaling network is a major, yet exciting challenge for future plant biological research. Research impact To enable cutting-edge research, my research group combines the disciplines phytopathology, entomology, biochemistry, molecular biology, and microbial ecology with the molecular genetic and genomic toolbox of the Arabidopsis model system. We have set up technologies and methods to study the complex dynamics of the plant immune response under conditions in which the plant interacts with beneficials and antagonists with different life styles and modes of attack, which is unique in the world. Our research led to multiple frequently cited papers (33 papers >100 cites; 2 papers > 1000 cites) in high-ranking general journals and top journals of the field of plant science. Investigations of my group on plant defense signaling have spread widely through the biology community and are frequently highlighted in primary literature, review articles and text books of Plant Molecular Biology (Buchanan et al.; Biochemistry & Molecular Biology of Plants), Plant Biology (Smith et al., Plant Biology), and Phytopathology (Slusarenko et al., Mechanisms of Resistance to Plant Diseases). 6/31

In 2015, an independent bibliometric analysis was performed on peer-reviewed publications of all 27 experimental plant sciences research groups in the Netherlands. With a citation impact of 6.31 times above world-average, the Plant-Microbe Interactions group had the highest Citation Index and the highest score of publications belonging to the top 1% most cited publications. In a similar bibliometric analysis for the Utrecht University in 2010, the Plant-Microbe Interactions group ranked 4 th out of 60 groups of the Faculty of Science (fields of Biology, Chemistry, Physics and Astronomy, Pharmaceutical Sciences, Information and Computing Sciences, and Mathematics). In 2011, the citation index of the PMI group ranked 1 st in the bibliometric CWTS analysis of all 11 groups of the Department of Biology. Since 2014, I m on the Highly Cited Researchers list of Thomson Reuters. This list contains over 3000 researchers (12 from UU) that are among the top 1% most cited for their subject field and year of publication. Future research In recent years, exciting new discoveries have greatly advanced our understanding of how the co-evolutionary arms race between plants and their attackers has shaped the plant immune system into a sophisticated defensive shield capable of warding off the majority of harmful organisms. Tremendous progress has also been made in the understanding of how plants respond to and benefit from mutualistic soil-borne microbes to maximize growth and survival. Under ecological and agricultural conditions, however, plants continuously interact with a complex of both beneficial and parasitic organisms. Hence, a major challenge is now to connect both research fields and unravel in detail how plants are able to simultaneously deal with mutualists and parasites and maximize profitable as well as protective functions. Besides exciting fundamental new insights into plant immune system functioning, this will open new ways for engineering durable resistance to pathogens and pests in crop plants. In the past years, my group intensively studied the plant immune systems that are recruited by beneficial and parasitic organisms. We demonstrated that the underlying signaling pathways intimately cross-communicate, enabling the plant to finely orchestrate its immune response to these alien organisms. Because plants have coevolved with an enormous variety of beneficial and parasitic organisms, they harbour a fantastic reservoir of natural mechanisms to respond to their biotic environment that to date remained largely unexploited. The overall aim of our research is to mine this natural resource to uncover novel key mechanisms of the plant immune system by which plants are able to simultaneously deal with beneficial and parasitic organisms. To this end, pursue an innovative multidisciplinary approach involving a unique combination of state-of-the-art microbial ecology, microbial and plant functional genomics, ecogenomics, molecular genetics, cellular biology, computational biology, bioinformatics and our unique expertise on plant immune system functioning to address the following key questions: How do host immune responses affect the beneficial microbial community in the rhizosphere? How do beneficial microbes evade local host immune responses? How is recognition of beneficial microbes in the root translated to systemic immunity? Which genes in the natural reservoir of Arabidopsis determine priming for enhanced defense? How do plants orchestrate their immune signaling network to deal simultaneously with beneficial and pathogenic microbes, or with multiple aggressors with distinct defense-activating properties? By performing frontier research we link the largely separated research fields engaged in unraveling plant immune responses to beneficial and to parasitic organisms. Hence, we hope to gain groundbreaking insights into the key regulatory processes of the plant immune system as it functions during multifaceted interactions with its complex biotic environment. Outcomes of our research will open up new possibilities for both basic and applied research on mechanisms of fundamental importance for plant survival in ecological and agricultural systems. Worldwide, plant diseases and pests cause yield losses of up to 25%. With our research, we aim to contribute to grand societal challenges, such as food security and sustainable agriculture. 7/31

RESEARCH GROUP, EMBEDDING AND COLLABORATIONS Plant-Microbe Interactions research group Besides myself, the Plant-Microbe Interactions research group comprises 2 associate professor (Dr. Guido van den Ackerveken, EMBO Young Investigator, VIDI; Dr. Saskia van Wees, VENI, VIDI), 2 assistant professors (Dr. Peter Bakker; Dr. Ronnie de Jonge, EMBO fellowship, FWO fellowship), 1 extaordinary professor (Prof. Marcel van der Heijden, VIDI), 10 post-docs (Drs. Richard Hickman (VENI), Colette Broekgaarden (VENI), Klaas Bouwmeester (VENI), Roeland Berendsen, Marcel van Verk, Silvia Proietti, Ivan Fernandez-Lopez, Irene Vos, Marco Cosme, Pauline Trapet, 12 PhD students, 4 technicians and 16 MSc students. Dr. van den Ackerveken is an EMBO Young Investigator Fellow and NWO-VIDI laureate and has extensive expertise with plant-microbe genetics, genomics and bioinformatics, and genetical mapping of disease resistance loci in Arabidopsis. Dr. van Wees is a NWO- VENI and VIDI laureate and a highly talented scientist with versatile research experience in the field of plant immunity signaling. Dr. Bakker is a microbial ecologist with a wealth of expertise on the analysis of microbial communities in the rhizosphere of plants. Dr. de Jonge is a plant-microbe bioinformatician. Prof. van der Heijden is an expert on mycorrhiza ecology. The combined expertise of these PMI staff members makes it possible to investigate the plant immune system from different angles and to perform at the international forefront of plant immune signaling research. The research group has access to new state-of-the-art plant growth facilities comprising 4 large walk-in climate chambers, well-equipped green house facilities, and all standard equipment for molecular biological and biochemical experiments. In addition, the group has access to high-quality light microscopes for fluorescence and nomarski imaging and uses high-quality confocal laser scanning microscopes which allows high-resolution detection of tissue-specific gene expression patterns and localization of proteins. Moreover, the group has ample in-house expertise with microbial community profiling, microarray analysis, bioinformatics of genomes, RNA-seq, phytohormone chemistry, the extensive molecular genetic and genomic toolbox of the Arabidopsis model system, and a large array of bioassays with diverse pathogens, insects, and beneficial microbes. Local infrastructure The group participates in the Institute of Environmental Biology and closely collaborates with members of the the Institute of Biodynamics & Bioinformatics of the Faculty of Science, Utrecht University. The PMI research participates in the strategic research areas Sustainability and Life Sciences and the focus areas Future Food Utrecht and Bioinformatics. The group has links with different research groups whose expertise and infrastructure are valuable for PMI research: Prof. Smeekens (IEB - Molecular Plant Physiology). Prof. Voesenek (IEB - Plant Ecophysiology Prof. Kowalchuk (IEB Ecology & Biodiversity) Prof. de Boer (IBB - Theoretical Biology) Prof. Snel (IBB - Bioinformatics) Prof. Wösten and Prof. Tomassen (IBB - Microbiology) Furthermore, within the Utrecht University the PMI group collaborates with: Prof. Heck of the Proteomics Institute (Chemistry/Mass Spectrometry) Prof. van Strijp (Utrecht Medical Centre/Medical Microbiology) Prof. Cuppen (Hubrecht Laboratory) Long-term collaborations The PMI group has a variety of long-term national and international collaborators who can be consulted for intellectual input, ad hoc collaborations or exchange of expertise. These include: Prof. Dicke (Entomology, Wageningen Univeristy): molecular ecology of plant-insect interactions and the translation of Arabidopsis-derived molecular knowledge on crosstalk to economically and 8/31

ecologically more relevant Brassica species. Prof. Memelink (Plant Cell Physiology, Leiden University): role of transcription factors in plant immunity. Dr. Raaijmakers (Microbial Ecology, NIOO): microbial ecology of beneficial Pseudomonas bacteria. Dr. Aarts (Genetics, Wageningen University): Arabidopsis genome-wide association mapping. Internationally, many links exist with internationally renowned research groups such as: Dr. Denby and Prof. Wild (Warwick Systems Biology Centre, UK): computational analysis of highdensity time series gene expression profiling. Prof. Goossens (VIB, Ghent University, Belgium): key regulators of JA signaling. Prof. Conrath (University of Aachen, Germany) and Prof. Mauch-Mani (University of Neuchatel, Switzerland): molecular mechanisms underlying the priming concept. Dr. Reymond (University of Lausanne, Switzerland): Arabidopsis-insect interactions. Dr. Ton (University of Sheffield, UK): Priming for enhanced defense. With all collaborators we have shared publications or is work ongoing that will yield shared publications in the near future. Besides academic partners, we have good relationships with industrial partners. Currently our group collaborates with or receives funding from the plant breeding companties ENZA Seeds, Royal Van Zanten, Rijk Zwaan, Bejo Seeds, Syngenta and the AgroBiotech companies Genetwister Technologies and KeyGene. 9/31

SUPERVISION AND TRAINING ACTIVITIES MSc students >65 performed a research project of 6-9 months under my supervison (1989-present). PhD students (thesis advisor, daily supervision by indicated co-promotor) Graduated 1. Saskia van Wees (1995-1999; with Prof. Kees van Loon) 2. Jurriaan Ton (1997-2001; with Prof. Kees van Loon) 3. Bas Verhagen 2000-2004; with Prof. Kees van Loon) 4. Martin de Vos (2001-2005; with Prof. Kees van Loon and Prof. Marcel Dicke) 5. Vivian van Oosten (2002-2006; with Prof. Marcel Dicke and Prof. Kees van Loon) 6. Sjoerd van der Ent (2003-2007; with Prof. Kees van Loon) 7. Annemart Koornneef (2004-2008; with Prof. Kees van Loon) 8. Marieke van Hulten (2005-2008; co-promotores Dr. Saskia van Wees & Dr. Jurriaan Ton) 9. Antonio Léon-Reyes (2005-2009; co-promotor Dr. Tita Ritsema) 10. Adriaan Verhage (2006-2011; co-promotor Dr. Saskia van Wees) 11. Dieuwertje van der Does (2007-2012; co-promotor Dr. Saskia van Wees) 12. Christos Zamioudis (2007-2012) 13. Tieme Zeilmaker (2006-2012; co-promotor Dr. Guido van den Ackerveken) 14. Roeland Berendsen (2006-2011; co-promotor Dr. Peter Bakker) 15. Inez Terpstra (2004-2012); co-promotor Dr. Guido van den Ackerveken) 16. Joost Stassen (2007-2012; co-promotor Dr. Guido van den Ackerveken) 17. Shakoor Ahmad (2008-2012; co-promotor Dr. Jurriaan Ton) 18. Chiel Pel (2008-2013) 19. Sharon Mithoe (2012-2013; with Prof. Albert Heck; daily supervisor Dr. Frank Menke) 20. Stan Oome (2009-2013; co-promotor Dr. Guido van den Ackerveken) 21. Dmitry Lapin (2009-2013; co-promotor Dr. Guido van den Ackerveken) 22. Irene Vos (2011-2015; co-promotor Dr. Saskia van Wees) 23. Yeling Zhou (2011-2016; co-promotores Dr. Saskia van Wees en Dr. Peter Bakker) 24. Lotte Caarls (2012-2016; co-promotores Dr. Saskia van Wees en Dr. Guido van den Ackerveken) 25. Nora Ludwig (2012-2016; co-promotor Guido van den Ackerveken) Ongoing 26. Silvia Coolen (2010-2014; co-promotor Dr. Saskia van Wees) 27. Giannis Stringlis (2012-2016) 28. Tom Raaijmakers (2013-2017; co-promotor Dr. Guido van den Ackerveken) 29. Ke Yu (2013-2017; co-promotor Dr. Peter Bakker and Dr. Roeland Berendsen) 30. Joël Klein (2013-2017; co-promotor Dr. Guido van den Ackerveken) 31. Alexandra Pelgrom (2014-2018; co-promotor Dr. Guido van den Ackerveken) 32. Merel Steenbergen (2014-2018; co-promotores Dr. Saskia van Wees and Dr. Colette Broekgaarden) 33. Erqin Li (2014-2018; co-promotor Dr. Alexandre Jousset and Dr. Peter Bakker) 34. Marciel Pereira Mendes (2014-2018; co-promotor Dr. Saskia van Wees and Dr. Marcel van Verk) 35. Eline Verbon (2015-2019; co-promotor Ronnie de Jonge) 36. Manon Neilen (2015-2019; co-promotor Dr. Guido van den Ackerveken) 37. Hao Zhang (2016-2020; co-promotor Ronnie de Jonge) 38. Gilles Vismans (2016-2020; co-promotores Peter Bakker and Roeland Berendsen) Post-docs 1. Dr. Karen M. Léon-Kloosterziel (1998-2000) 2. Dr. Shu Hase (2000-2001) 3. Dr. Frank Menke (2003) 4. Dr. Maria José Pozo-Jimenez (2003-2005; Marie-Curie Fellow) 10/31

5. Dr. Jurriaan Ton (2004-2008 (VENI Fellow) 6. Dr. Tita Ritsema (2005-2010) 7. Dr. Sjoerd van der Ent (2008-2009) 8. Dr. Annemart Koornneef (2008) 9. Dr. Saskia van Wees (2007-2011; VIDI Fellow) 10. Dr. Marcel van Verk (2011-2016) 11. Dr. Richard Hickman (2012-2017; VENI Fellow) 12. Dr. Christos Zamioudis (2012-2014) 13. Dr. Roeland Berendsen (2011-2015) 14. Dr. Ainhoa Martinez-Medina (2012-2014; Marie-Curie Fellow) 15. Dr. Silvia Proietti (2013-2015; Marie-Curie Fellow) 16. Dr. Ivan Fernandez-Lopez (2014-2017; Marie Curie Fellow) 17. Dr. Klaas Bouwmeester (2014-2017; VENI Fellow) 18. Dr. Colette Broekgaarden (2014-2018; VENI Fellow) 19. Dr. Marco Cosme (2015-2017) 20. Dr. Pauline Trapet (2016-2019) 21. Dr. Irene Vos (2015-2016) 22. Dr. Lotte Caarls (2016) Technicians 1. Hans van Pelt (1993-present) 2. Ientse van der Sluis (2006-2012) 3. Joost Keurentjes (2000-2001) 4. Ruth Joosten (2005-2007) 5. Anja van Dijken (2011-present) Foreign guest researchers hosted in the group (3-6 months) 1. Juan Sobrino Plata (Spain; 2016) 2. Xiuyan Li (China; 2015) 3. David Weller (USA; 2013) 4. Ivan Fernandez López (Spain; 2013) 5. Mercedes Maldonado Gonzalez (Spain; 2013) 6. Fernando Faz Saura (Spain; 2012) 7. Ana Murcia Meseguer (Spain; 2012) 8. Amparo Cuéllar-Pérez (Belgium; 2011) 9. Anna Lanteri (Italy; 2011) 10. Prof. Martin Filion (Canada; 2010) 11. Tanya Arseneault (Canada; 2010) 12. Swadhin Swain (India; 2010) 13. Sabine Jung (Spain; 2009) 14. Cristina Rioja (Spain; 2009, 2011) 15. Fotis Bekris (Greece; 2008) 16. Silvia Proietti (Italy; 2008) 17. Hana Návarová (Tsjech Republic; 2008) 18. Abdolreza Akhgar (Iran; 2008) 19. Miguel Matilla Vasques (Spain; 2007) 20. Guillem Segarra (Spain; 2007) 21. Matthias Erb (Switzerland; 2006) 22. Ulrike Bechtold (UK; 2006) Member of external PhD thesis evaluation committees of: 1. F. Menke, Leiden University, the Netherlands (1999) 2. P.D. Shivakumar, University of Mysore, India (2001) 3. T.W. Prins, Wageningen University, the Netherlands (2001) 4. H.M. Geetha, University of Mysore, India (2003) 11/31

5. M. Atallah, Leiden University, the Netherlands (2005) 6. M. Visker, Wageningen University, the Netherlands (2005) 7. Duyvensteijn, University of Amsterdan, the Netherlands (2006) 8. S. Gabriëls, Wageningen University, the Netherlands (2006) 9. K. Ament, University of Amsterdam, the Netherlands (2006) 10. M. Pré, Leiden University, the Netherlands (2006) 11. T. Scheublin, Vrije Universiteit Amsterdam, the Netherlands (2006) 12. M.M.A. van Damme, Utrecht University, the Netherlands (2007) 13. M. Djavaheri, Utrecht University, the Netherlands (2007) 14. F. Rahmani, Utrecht University, the Netherlands (2007) 15. K. Van Driel, Utrecht University, the Netherlands (2007) 16. G. Segarra, University of Barcelona, Spain (2008) 17. H. van Leur, NIOO, Wageningen University, the Netherlands (2008) 18. M. de Jong, Utrecht University, the Netherlands (2008) 19. T. Djakovic, Utrecht University, the Netherlands (2008) 20. J. van Galen, Utrecht University, the Netherlands (2008) 21. I. Stulemeier, Wageningen University, the Netherlands (2008) 22. Z. Heydarian, Utrecht University, the Netherlands (2008) 23. van Peer, Utrecht University, the Netherlands (2008) 24. R. Huibers, Utrecht University, the Netherlands (2008) 25. E. Poelman, Wageningen University, the Netherlands (2008) 26. L. van der Does, University of Amsterdam, the Netherlands (2008) 27. B. van Schooten, University of Amsterdam, the Netherlands (2008) 28. M. Groenenboom, Utrecht University, the Netherlands (2008) 29. T. van Molken, Radboud University Nijmegen, the Netherlands (2009) 30. R. Aghnoum, Wageningen University, the Netherlands (2009) 31. T. Snoeren, Wageningen University, the Netherlands (2009) 32. U. Ellendorf, Wageningen University, the Netherlands (2009) 33. Y. Millet, University of Strassbourg, France (2009) 34. M. Hanssen, Utrecht University, the Netherlands (2009) 35. M. van Zanten, Utrecht University, the Netherlands (2009) 36. W. Teertstra, Utrecht University, the Netherlands (2009) 37. R. Doornbos, Utrecht University, the Netherlands (2009) 38. G. Beckers, RWTH Aachen University, Aachen, Germany (2009) 39. K. Bouwmeester, Wageningen University, the Netherlands (2010) 40. N. Champouret, Wageningen University, the Netherlands (2010) 41. C. ten Hove, Utrecht University, the Netherlands (2010) 42. T. Gomas, Radboud University Nijmegen, the Netherlands (2010) 43. A. Korbes, Leiden University, the Netherlands (2010) 44. M. Hummel, Utrecht University, the Netherlands (2011) 45. N. Kip, Radboud University Nijmegen, the Netherlands (2011) 46. E. Battaglia, Utrecht University, the Netherlands (2011) 47. B. Bardoel, Utrecht University, the Netherlands (2011) 48. A. Mhamdi, University of Paris, France (2011) 49. S. Allmann, University of Amsterdam, the Netherlands (2011) 50. S. Meldau, Max Planck Institute, Jena, Germany (2011) 51. M. de Wit, Utrecht University, the Netherlands (2012) 52. L.Q Huy, Utrecht University, the Netherlands (2012) 53. M. Khurshid, Leiden University, the Netherlands (2012) 54. J. Ma, Utrecht University, the Netherlands (2012) 55. J. Wind, Utrecht University, the Netherlands (2012) 56. P. Sedijani, Utrecht University, the Netherlands (2012) 57. L. Xu, Utrecht University, the Netherlands (2012) 58. A.S. Gsell, Utrecht University, the Netherlands (2013) 59. M. Seidl, Utrecht University, the Netherlands (2013) 60. K. de Cremer, University of Leuven, Belgium (2013) 12/31

61. X. Zhang, Utrecht University, the Netherlands (2013) 62. W. Kegge, Utrecht University, the Netherlands (2013) 63. A. Cuéllar-Pérez, University of Ghent, Belgium (2013) 64. I. Fernandez López, University of Granada, Spain (2013) 65. G.W. van Esse, Wageningen University, the Netherlands (2013) 66. T.-P. Nguyen, Utrecht University, the Netherlands (2014) 67. J. Glas, University of Amsterdam, the Netherlands (2014) 68. J.L. Lozano Torres, Wageningen University, the Netherlands (2014) 69. A.B. Wolf, Utrecht University, the Netherlands (2014) 70. W. Quaedvlieg, Utrecht University, the Netherlands (2014) 71. F. Wang, Utrecht University, the Netherlands (2014) 72. B. Vadakkemukadiyil Chellappan, University of Amsterdam (2014) 73. B. Chen, Utrecht University, the Netherlands (2015) 74. J. Lastdrager, Utrecht University, the Netherlands (2015) 75. N. Yilmaz, Utrecht University, the Netherlands (2015) 76. S. Klaubauf, Utrecht University, the Netherlands (2015) 77. N. Yilmaz, Utrecht University, the Netherlands (2015) 78. J. Lastdrager, Utrecht University, the Netherlands (2015) 79. P. Gankema, Utrecht University, the Netherlands (2015) 80. A. Scala, University of Amsterdam, the Netherlands (2015) 81. C. Seyfferth, University of Cologne, Germany (2015) 82. B. Bai, Utrecht University, the Netherlands (2016) 83. A. Pandey, Utrecht University, the Netherlands (2016) 84. A. Schmiesing, University of Lausanne, Switzerland (2016) 85. D. Nguyen, Radboud University Nijmegen, the Netherlands (2016) 86. K. Zhang, Leiden University, the Netherlands (2016) 13/31

PUBLICATIONS To access publications see http://www.uu.nl/en/research/plant-microbe-interactions Number of publications in international refereed scientific journals: 122 Number of publicatons cited >100 times: 33; >1000 times: 2. Number of citations according to ISI Web of Science (May 2016): 13.278 Number of citations according to Google Scholar (May 2016): 21.504 Hirsch-index (Web of Science search string: Pieterse CM*, or ResearcherID: A-9326-2011): 53 Hirsch-index (Google Scholar Citations): 60 Average number of citations per publication: 103 Contributions to books: 48 Patent applications: 2 Median Impact Factor Category Plant Sciences of Thomson s JCR 2013: IF 1.34 Cut-off top 10% Journals in Category Plant Sciences = IF 3.9; # of top 10% publications: 70 2015: PMI group highest Citation Impact of all 27 Dutch Experimental Plant Sciences research groups. 2014+2015: Thomson Reuters Highly Cited Researcher 2011: PMI group ranked 1 st in bibliometric CWTS analysis of all 11 groups of the Department of Biology. 2009: PMI group ranked 4 th in bibliometric CWTS analysis of all 60 research groups of the Faculty of Science. Peer-reviewed publications in international refereed journals (in chronological order) 1. Pieterse, C.M.J., Risseeuw, E.P. and Davidse, L.C. (1991). An in planta induced gene of Phytophthora infestans codes for ubiquitin. Plant Mol. Biol. 17: 799-811. 2. Pieterse, C.M.J., de Wit, P.J.G.M. and Govers, F. (1992). Molecular aspects of the potato-phytophthora infestans interaction. Neth. J. Plant Pathol. 98 Supplement 2: 85-92. 3. Judelson, H.S., Dudler, R., Pieterse, C.M.J., Unkles, S.E. and Michelmore, R.W. (1993). Expression and antisense inhibition of transgenes in Phytophthora infestans is modulated by choice of promoter and position effects. Gene 133: 63-69. 4. Pieterse, C.M.J., Riach, M.B.R., Bleker, T., Van Berg-Velthuis, G.C.M. and Govers, F. (1993). Isolation of putative pathogenicity genes of the potato late blight fungus Phytophthora infestans by differential hybridization of a genomic library. Physiol. Mol. Plant Pathol. 43: 69-79. 5. Pieterse, C.M.J., Verbakel, H.M., Hoek Spaans, J., Davidse, L.C. and Govers, F. (1993). Increased expression of the calmodulin gene of the late blight fungus Phytophthora infestans during pathogenesis on potato. Mol. Plant-Microbe Interact. 6: 164-172. 6. Pieterse, C.M.J., Van West, P., Verbakel, H.M., Brassé, P.W.H.M., Van den Berg-Velthuis, G.C.M. and Govers, F. (1994). Structure and genomic organization of the ipib and ipio gene clusters of Phytophthora infestans. Gene 138: 67-77. 7. Pieterse, C.M.J., Derksen, A.-M.C.E., Folders, J. and Govers, F. (1994). Expression of the ipib and ipio genes of Phytophthora infestans in planta and in vitro. Mol. Gen. Genet. 244: 269-277. 8. Pieterse, C.M.J., Van 't Klooster, J., Van den Berg-Velthuis, G.C.M. and Govers, F. (1995). NiaA, the structural nitrate reductase gene of Phytophthora infestans: Isolation, characterization and analysis in Aspergillus nidulans. Curr. Genet. 27: 359-366. 9. Hoffland, E., Pieterse, C.M.J., Bik, L. and Van Pelt, J.A. (1995). Systemic induced resistance in radish is not associated with accumulation of pathogenesis-related proteins. Physiol. Mol. Plant Pathol. 46: 309-320. 10. Pieterse, C.M.J., Van Wees, S.C.M., Hoffland, E., Van Pelt, J.A. and Van Loon, L.C. (1996). Systemic resistance in Arabidopsis induced by biocontrol bacteria is independent of salicylic acid accumulation and pathogenesis-related gene expression. Plant Cell 8: 1255-1237. 11. Van Wees, S.C.M., Pieterse, C.M.J., Trijssenaar, A., Van 't Westende, Y.A.M., Hartog, F. and Van Loon, L.C. (1997). Differential induction of systemic resistance in Arabidopsis by biocontrol bacteria. Mol. Plant-Microbe Interact. 10: 716-724. 12. Pieterse, C.M.J., Van Wees, S.C.M., Van Pelt, J.A., Knoester, M., Laan, R., Gerrits, H., Weisbeek, P.J. and Van Loon, L.C. (1998). A novel signalling pathway controlling induced systemic resistance in Arabidopsis. Plant Cell 10: 1571-1580. 14/31

13. Van Loon, L.C., Bakker, P.A.H.M. and Pieterse, C.M.J. (1998). Plant growth-promoting rhizobacteria induced systemic resistance. Annu. Rev. Phytopathol. 36: 453-483. 14. Pieterse, C.M.J. and Van Loon, L.C. (1999). Salicylic acid-independent plant defence pathways. Trends Plant Sci. 4: 52-58. 15. Knoester, M., Pieterse, C.M.J., Bol, J.F. and Van Loon, L.C. (1999). Systemic resistance in Arabidopsis induced by rhizobacteria requires ethylene-dependent signalling at the site of application. Mol. Plant- Microbe Interact. 12: 720-727. 16. Ton, J., Pieterse, C.M.J. and Van Loon, L.C. (1999). Identification of a locus in Arabidopsis controlling both the expression of rhizobacteria-mediated induced systemic resistance (ISR) and basal resistance against Pseudomonas syringae pv. tomato. Mol. Plant-Microbe Interact. 12: 911-918. 17. Van Wees, S.C.M., Luijendijk, M., Smoorenburg, I., Van Loon, L.C. and Pieterse, C.M.J. (1999). Rhizobacteria-mediated induced systemic resistance (ISR) in Arabidopsis is not associated with a direct effect on expression of known defence-related genes, but stimulates the expression of the jasmonateinducible gene Atvsp upon challenge. Plant Mol. Biol. 41: 537-549. 18. Pieterse, C.M.J., Van Pelt, J.A., Ton, J., Parchmann, S., Mueller, M.J., Buchala, A.J., Métraux, J.-P. and Van Loon, L.C. (2000). Rhizobacteria-mediated induced systemic resistance in Arabidopsis requires sensitivity to jasmonate and ethylene but is not accompanied by an increase in their production. Physiol. Mol. Plant Pathol. 57: 123-134. 19. Van Wees, S.C.M., De Swart, E.A.M., Van Pelt, J.A., Van Loon, L.C. and Pieterse, C.M.J. (2000). Enhancement of induced disease resistance by simultaneous activation of salicylate- and jasmonatedependent defence pathways in Arabidopsis thaliana. Proc. Nat. Acad. Sci. USA 97: 8711-8716. 20. Pieterse, C.M.J., Ton, J. and Van Loon, L.C. (2001). Cross-talk between plant defence signalling pathways: boost or burden? AgBiotechNet 3: ABN 068. 21. Pieterse, C.M.J., Van Pelt, J.A., Van Wees, S.C.M., Ton, J., Léon-Kloosterziel, K.M., Keurentjes, J.J.B., Verhagen, B.W.M., Knoester, M., Van der Sluis, I., Bakker, P.A.H.M. and Van Loon, L.C. (2001). Rhizobacteria-mediated induced systemic resistance: triggering, signalling, and expression. Eur. J. Plant Pathol. 107: 51-61. 22. Ton, J., Davison, S., Van Loon, L.C. and Pieterse, C.M.J. (2001). Heritability of rhizobacteria-mediated induced systemic resistance and basal resistance in Arabidopsis. Eur. J. Plant Pathol. 107: 63-68. 23. Ton, J., Davison, S., Van Wees, S.C.M., Van Loon, L.C. and Pieterse, C.M.J. (2001). The Arabidopsis ISR1 locus controlling rhizobacteria-mediated induced systemic resistance is involved in ethylene signalling. Plant Physiol. 125: 652-661. 24. Conrath, U., Pieterse, C.M.J. and Mauch-Mani, B. (2002). Priming in plant-pathogen interactions. Trends Plant Sci. 7: 210-216. 25. Ton, J., De Vos, M., Robben, C., Buchala, A.J., Métraux, J.-P., Van Loon, L.C. and Pieterse, C.M.J. (2002). Characterisation of Arabidopsis enhanced disease susceptibility mutants that are affected in systemically induced resistance. Plant J. 29: 11-21. 26. Ton, J., Van Pelt, J.A., Van Loon, L.C. and Pieterse, C.M.J. (2002). Differential effectiveness of salicylatedependent and jasmonate/ethylene-dependent induced resistance in Arabidopsis. Mol. Plant Microbe- Interact. 15: 27-34. 27. Ton, J., Van Pelt, J.A., Van Loon, L.C. and Pieterse, C.M.J. (2002). The Arabidopsis ISR1 locus is required for rhizobacteria-mediated induced systemic resistance against different pathogens. Plant Biol. 4: 224-227. 28. Pieterse, C.M.J., Van Wees, S.C.M., Ton, J., Van Pelt, J.A. and Van Loon, L.C. (2002). Signalling in rhizobacteria-induced systemic resistance in Arabidopsis. Plant Biol. 4: 535-544. 29. Pieterse, C.M.J., Van Pelt, J.A., Verhagen, B.W.M., Ton, J., Van Wees, S.C.M., Léon-Kloosterziel, K.M. and Van Loon, L.C. (2003). Induced systemic resistance by plant growth-promoting rhizobacteria. Symbiosis 35: 39-54. 30. Spoel, S.H., Koornneef, A., Claessens, S.M.C., Korzelius, J.P., Van Pelt, J.A., Mueller, M.J., Buchala, A.J., Métraux, J.-P., Brown, R., Kazan, K., Van Loon, L.C., Dong, X., and Pieterse, C.M.J. (2003) Cytosolic NPR1 modulates cross talk between salicylate- and jasmonate-dependent plant defence pathways. Plant Cell 15: 760-770. 31. Bakker, P.A.H.M., Ran, L.X., Pieterse, C.M.J. and Van Loon, L.C. (2003) Understanding the involvement of induced systemic resistance in rhizobacteria-mediated biocontrol of plant diseases. Can. J. Plant Pathol. 25: 5-9. 15/31

32. Hase, S., Van Pelt, J.A., Van Loon, L.C. and Pieterse, C.M.J. (2003). Colonization of Arabidopsis roots by Pseudomonas fluorescens primes the plant to produce higher levels of ethylene upon pathogen infection. Physiol. Mol. Plant Pathol. 62: 219-226. 33. Schuurmans, J.A.M.J., Van Dongen, J.T., Rutjens, B.P.W., Boonman, A., Pieterse, C.M.J. and Borstlap, A.C. (2003). Members of the aquaporin family in the developing pea seed coat include representatives of the PIP, TIP and NIP subfamilies. Plant Mol. Biol. 53: 655-677. 34. Menke, F.L.H., Van Pelt, J.A., Pieterse, C.M.J. and Klessig, D.F. (2004). Silencing of Arabidopsis MAP kinase 6 compromises disease resistance. Plant Cell 16: 897-907. 35. Verhagen, B.W.M., Glazebrook, J., Chang, H.-S., Zou, G., Zhu, T., Van Loon, L.C. and Pieterse, C.M.J. (2004). The transcriptome of rhizobacteria-induced systemic resistance (ISR) in Arabidopsis. Mol. Plant- Microbe Interact. 17: 895-908. 36. Pieterse, C.M.J. and Van Loon, L.C. (2004). NPR1: the spider in the web of induced resistance signaling pathways. Curr. Opinion Plant Biol. 7: 456-464. 37. Pozo, M.J. and Van Loon, L.C. and Pieterse, C.M.J. (2004). Jasmonates signals in plant-microbe interactions. J. Plant Growth Regul. 23: 211-222. 38. Léon-Kloosterziel, K.M., Verhagen, B.W.M., Keurentjes, J.J.B., Van Pelt, J.A., Rep, M., Van Loon, L.C. and Pieterse, C.M.J. (2005). Colonization of the Arabidopsis rhizosphere by fluorescent Pseudomonas spp. activates a root-specific, ethylene-responsive PR-5 gene in the vascular bundle. Plant Mol. Biol. 57:731-748. 39. De Vos, M., Van Oosten, V.R., Van Poecke, R.M.P., Van Pelt, J.A., Pozo, M.J., Mueller, M.J., Buchala, A.J., Métraux, J.-P., Van Loon, L.C., Dicke, M. and Pieterse, C.M.J. (2005). Signal signature and transcriptome changes in Arabidopsis upon pathogen and insect attack. Mol. Plant-Microbe Interact. 18: 923-937. 40. Pieterse, C.M.J., Van Pelt, J.A., Van Wees, S.C.M., Ton, J., Verhagen, B.W.M., Léon-Kloosterziel, K., Hase, S., De Vos, M., Van Oosten, V., Pozo, M., Spoel, S., Van der Ent, S., Koornneef, A., Chalfun- Junior, A., Resende, M.L.V. and Van Loon, L.C. (2005). Indução de resistência sistêmica por rizobactérias e comunicação na rota de sinalização para uma defesa refinada. Revisão de Patologia de Plantas 13: 277-319. 41. Van Hulten, M., Pelser, M., Van Loon, L.C., Pieterse, C.M.J., and Ton, J. (2006). Costs and benefits of priming for defense in Arabidopsis. Proc. Natl. Acad. Sci. USA 103: 5602-5607. 42. Conrath, U., Beckers, G.J.M., Flors, V., Garcia-Agustin, P., Jakab, G., Mauch, F., Newman, M.-A., Pieterse, C.M.J., Poinssot, B., Pozo, M.J., Pugin, A., Schaffrath, U., Ton, J., Wendehenne, D., Zimmerli, L. and Mauch-Mani, B. (2006). Priming: getting ready for battle. Mol. Plant-Microbe Interact. 19: 1062-1071. 43. De Vos, M., Van Zaanen, W., Koornneef, A., Korzelius, J.P., Dicke, M., Van Loon, L.C. and Pieterse, C.M.J. (2006). Herbivore-induced resistance against microbial pathogens in Arabidopsis. Plant Physiol. 142: 352-363. 44. Van Loon, L.C., Rep, M. and Pieterse, C.M.J. (2006). Significance of inducible defense-related proteins in infected plants. Annu. Rev. Phytopathol. 44: 135-162. 45. De Vos, M., Denekamp, M., Dicke, M., Vuylsteke, M., Van Loon, L.C., Smeekens, S.C.M. and Pieterse, C.M.J. (2006). The Arabidopsis thaliana transcription factor AtMYB102 functions in defense against the insect herbivore Pieris rapae. Plant Signaling & Behavior 1: 305-311. 46. Bakker, P.A.H.M., Pieterse, C.M.J. and Van Loon, L.C. (2007). Induced systemic resistance by fluorescent Pseudomonas spp. Phytopathology 97, 239-243. 47. Ritsema, T., Joore, J., Van Workum, W. and Pieterse, C.M.J. (2007). Kinome profiling of Arabidopsis using arrays of kinase consensus substrates. Plant Methods 3: 3. 48. De Vos, M., Van Oosten, V.R., Jander, G., Dicke, M., and Pieterse, C.M.J. (2007). Plants under attack: multiple interactions with insects. Plant Signaling & Behavior 2: 527-529. 49. Pieterse, C.M.J. and Dicke, M. (2007). Plant interactions with microbes and insects: from molecular mechanism to ecology. Trends Plant Sci. 12: 564-569. 50. Van der Ent, S., Verhagen, B.W.M., Van Doorn, R., Bakker, D., Verlaan, M.G., Pel, M.J.C., Joosten, R.G., Proveniers, M.C.G., Van Loon, L.C., Ton, J. and Pieterse, C.M.J. (2008). MYB72 is required in early signaling steps of rhizobacteria-induced systemic resistance in Arabidopsis. Plant Physiol. 146:1293-1304. 51. Koornneef, A. and Pieterse, C.M.J. (2008). Cross-talk in defense signaling. Plant Physiol. 146: 839-844. 16/31

52. Van Oosten, V.R., Bodenhausen, N., Reymond, P., Van Pelt, J.A., Van Loon, L.C., Dicke, M. and Pieterse, C.M.J. (2008). Differential effectiveness of microbially induced resistance against herbivorous insects in Arabidopsis. Mol. Plant-Microbe Interact. 21: 919-930. 53. Koornneef, A., Verhage, A., Leon-Reyes, A., Snetselaar, R., Van Loon, L.C., and Pieterse, C.M.J. (2008). Towards a reporter system to identify regulators of cross-talk between salicylate and jasmonate signaling pathways in Arabidopsis. Plant Signaling & Behavior 3: 543-546. 54. Schenk, P.M., McGrath, K.C., Lorito, M. and Pieterse, C.M.J. Pieterse (2008). Plant-microbe and plantinsect interactions meet common grounds. New Phytologist 179: 251-256. 55. Koornneef, A., Leon-Reyes, A. Ritsema, T., Verhage, A., Den Otter, F.C., Van Loon, L.C. and Pieterse, C.M.J. (2008). Kinetics of salicylate-mediated suppression of jasmonate signaling reveal a role for redox modulation. Plant Physiol. 147: 1358-1368. 56. Pré, M., Atallah, M., Champion, A., De Vos, M., Pieterse, C.M.J. and Memelink, J. (2008). The AP2/ERFdomain transcription factor ORA59 integrates jasmonic acid and ethylene signals in plant defense. Plant Physiol. 147: 1347-1357. 57. Pozo, M.J., Van der Ent, S., Van Loon, L.C. and Pieterse, C.M.J. (2008). The transcription factor MYC2 is involved in priming for enhanced defense during rhizobacteria-induced systemic resistance in Arabidopsis. New Phytologist 180: 511-523. 58. Van Wees, S.C.M., Van der Ent, S. and Pieterse, C.M.J. (2008). Plant immune responses triggered by beneficial microbes. Curr. Opinion Plant Biol. 11: 443-448. 59. Koornneef, A., Rindermann, K., Gatz, C. and Pieterse, C.M.J. (2008). Histone modifications do not play a major role in salicylate-mediated suppression of jasmonate-induced PDF1.2 gene expression. Communicative & Integrative Biology 1: 143-145 60. Pieterse, C.M.J., Leon-Reyes, A., Van der Ent, S. and Van Wees, S.C.M. (2009). Networking by smallmolecule hormones in plant immunity. Nature Chemical Biology. 5: 308-316. 61. Segarra, G., Van der Ent, S., Trillas, I. and Pieterse, C.M.J. (2009). MYB72, a node of convergence in induced systemic resistance triggered by a fungal and a bacterial beneficial microbe. Plant Biology 11: 90-96. 62. Van der Ent, S., Van Hulten, M.H.A., Pozo, M.J., Czechowski, T., Udvardi, M.K., Pieterse, C.M.J. and Ton, J. (2009). Priming of plant innate immunity by rhizobacteria and ß-aminobutyric acid: differences and similarities in regulation. New Phytologist 183: 419-431. 63. Leon-Reyes, A., Spoel, S.H., De Lange, E.S., Abe, H., Kobayashi, M., Tsuda, S., Millenaar, F.F., Welschen, R., Ritsema, T. and Pieterse, C.M.J. (2009). Ethylene modulates the role of NPR1 in cross-talk between salicylate and jasmonate signaling. Plant Physiol. 149: 1797-1809. 64. Bargmann, B.OR., Laxalt, A.M., Riet, B., Testerink, C., Merquiol, E., Mosblech, A., Leon-Reyes, A., Pieterse, C.M.J., Haring, M.A., Heilmann, I., Bartels, D. and Munnik, T. (2009). Reassessing the role of phospholipase D in the Arabidopsis wounding response. Plant, Cell Environm. 32:837-850. 65. Ritsema, T., Brodmann, D., Diks, S.H., Bos, C.L., Nagaraj, V., Pieterse, C.M.J., Boller, T., Wiemken, A. and Peppelenbosch, M.P. (2009). Are small GTPases signal hubs in sugar-mediated induction of fructan biosynthesis? PLoS ONE 4: e6605. 66. Van der Ent, S., Van Wees, S.C.M. and Pieterse, C.M.J. (2009). Jasmonate signaling in plant interactions with resistance-inducing beneficial microbes. Phytochemistry 70: 1581-1588. 67. Leon-Reyes, A., Du, Y., Koornneef, A., Proietti, S., Körbes, A.P., Memelink, J., Pieterse, C.M.J. and Ritsema, T. (2009). Ethylene signaling renders the jasmonate response of Arabidopsis insensitive to future suppression by salicylic acid. Mol. Plant-Microbe Interact. 23: 187-197. 68. Pineda, A., Zheng, S.-J., Van Loon, J.J.A., Pieterse, C.M.J.,and Dicke, M. (2010). Helping plants to deal with insects: the role of beneficial soil-borne microbes. Trends Plant Sci. 15: 507-514. 69. Verhage, A., Van Wees, S.C.M. and Pieterse, C.M.J. (2010). Plant immunity: It s the hormones talking, but what do they say?. Plant Physiol. 154: 536-540. 70. Leon-Reyes, A., De Lange, E.S., Ritsema, T. and Pieterse, C.M.J. (2010). Salicylate-mediated supresión of jasmonate-responsive gene expression in Arabidopsis is targeted downstream of the jasmonate biosynthesis pathway. Planta 232: 1423-1432. 71. Ramírez, V., Van der Ent, S., García-Andrade, J., Coego, A., Pieterse, C.M.J. and Vera, P. (2010). OCP3 is an important modulator of NPR1-mediated jasmonic acid-dependent induced defenses in Arabidopsis. BMC Plant Biology 10: 199 17/31

72. Ritsema, T., Van Zanten, M., Leon-Reyes, A., Voesenek, L.A.C.J., Millenaar, F.F., Pieterse, C.M.J. and Peeters, A.J.M. (2010). Kinome profiling reveals an interaction between jasmonate, salicylate and light control of hyponastic petiole growth in Arabidopsis thaliana. PLoS ONE 5: e14255 73. Verhage, A., Vlaardingerbroek, I., Raaijmakers, C., Van Dam, N.M, Dicke, M., Van Wees, S.C.M. and Pieterse, C.M.J. (2011). Rewiring of the jasmonate signaling pathway in Arabidopsis during insect herbivory. Frontiers in Plant Science 2: 47 74. Swain, S., Roy, S., Shah, J., Van Wees, S.C.M, Pieterse, C.M.J. and Nandi, A.K. (2011). Arabidopsis thaliana cdd1 mutant uncouples constitutive activation of salicylic acid signaling from growth defects. Mol. Plant Pathol. 12: 855-865 75. Proietti, S., Bertini, L., Van der Ent, S., Leon-Reyes, A., Pieterse, C.M.J., Tucci, M., Caporale, C. and Caruso, C. (2011). Cross activity of orthologous WRKY transcription factors in wheat and Arabidopsis. J. Exp. Bot. 62: 1975-1990 76. Bardoel, B.W., Van der Ent, S., Pel, M.J.C, Tommassen, J., Pieterse, C.M.J., Van Kessel, K.P.M. and Van Strijp, J.A.G. (2011). Pseudomonas evades immune recognition of flagellin in both mammals and plants. PLoS Pathogens 7: e1002206 77. Ahmad, S., Van Hulten, M., Martin, J., Pieterse, C.M.J., Van Wees, S.C.M. and Ton, J. (2011). Genetic dissection of basal defence responsiveness in accessions of Arabidopsis thaliana. Plant, Cell Environm. 34: 1191 1206 78. Zamioudis, C. and Pieterse, C.M.J. (2012). Modulation of host immunity by beneficial microbes. Mol. Plant-Microbe Interact. 25: 139-150 79. Weller, D.M., Mavrodi, D.V., Van Pelt, J.A., Pieterse, C.M.J., Van Loon, L.C. and Bakker, P.A.H.M. (2012). Induced systemic resistance (ISR) in Arabidopsis thaliana against Pseudomonas syringae pv. tomato by 2,4-diacetylphloroglucinol-producing Pseudomonas fluorescens. Phytopathology 102: 403-412 80. Van Zanten, M., Ritsema, T., Polko, J.K., Leon-Reyes, A., Voesenek, L.A.C.J., Millenaar, F.F., Pieterse, C.M.J. and Peeters, A.J.M. (2012). Modulation of ethylene and heat-controlled hyponastic leaf movement in Arabidopsis thaliana by the plant defense hormones jasmonate and salicylate. Planta 235: 677 685 81. Pieterse, C.M.J. (2012). Prime time for transgenerational defense. Plant Physiology 158: 545 82. Pieterse, C.M.J., Van der Does, D., Zamioudis, C., Leon-Reyes, A. and Van Wees, S.C.M. (2012). Hormonal modulation of plant immunity. Annu. Rev. Cell Dev. Biol. 28: 489-521 83. Cerrudo, I., Keller, M.M., Cargnel, M.D., Demkura, P.V., De Wit, M., Patitucci, M.S., Pierik, R., Pieterse, C.M.J. and Ballaré, C.L. (2012). Low Red:Far-Red ratios reduce Arabidopsis resistance to Botrytis cinerea and jasmonate responses via a COI1-JAZ10-dependent, salicylic acid-independent mechanism. Plant Physiol. 158: 2042 2052 84. Berendsen, R.L., Pieterse, C.M.J. and Bakker, P.A.H.M. (2012). The rhizosphere microbiome and plant health. Trends Plant Sci. 17: 478-486 85. Alizadeh, H., Behboudi, K., Amadzadeh, M., Javan-Nikkhah, M., Zamioudis, C., Pieterse, C.M.J. and Bakker, P.A.H.M. (2013). Induced systemic resistance in cucumber and Arabidopsis thaliana by the combination of Trichoderma harzianum Tr6 and Pseudomonas sp. Ps14. Biological Control 65: 14-23 86. Pel, M.J.C. and Pieterse, C.M.J. (2013). Microbial recognition and evasion of host immunity. J. Exp. Bot. 64: 1237 1248 87. Rioja, C., Van Wees, S.C.M., Charlton, K.A., Pieterse, C.M.J., Lorenzo, O. and García-Sánchez, S. (2013). Wide screening of phage-displayed libraries identifies immune targets in planta. PLoS ONE 8: e54654 88. Van der Does, D., Leon-Reyes, A., Koornneef, A., Van Verk, M.C., Rodenburg, N., Pauwels, L., Goossens, A., Körbes, A., Memelink, J., Ritsema, T., Van Wees, S.C.M. and Pieterse, C.M.J. (2013). Salicylic acid suppresses jasmonic acid signaling downstream of SCFCOI1-JAZ by targeting GCC promoter motifs via transcription factor ORA59. Plant Cell 25: 744 761 89. Van Verk, M.C., Hickman, R., Pieterse, C.M.J. and Van Wees, S.C.M. (2013). RNA-Seq: revelation of the messengers. Trends Plant Sci. 18: 175-179 90. Zamioudis, C., Mastranesti, P., Dhonukshe, P., Blilou, I. and Pieterse, C.M.J. (2013). Unraveling root developmental programs initiated by beneficial Pseudomonas bacteria. Plant Physiol. 162: 304-318 91. De Wit, M., Spoel, S.H., Sanchez-Perez, G.F., Gommers, C.M.M., Pieterse, C.M.J., Voesenek, L.A.C.J. and Pierik, R. (2013). Perception of low Red:Far-red ratio compromises both salicylic acid- and jasmonic acid-dependent pathogen defences in Arabidopsis. Plant J. 75: 90-103 92. Bakker, P.A.H.M., Doornbos, R.F., Zamioudis, C., Berendsen, R.L. and Pieterse, C.M.J. (2013). Induced systemic resistance and the rhizosphere microbiome. Plant Pathol. J. 29: 136-143. 18/31

93. Lopes da Veiga, R.S., Faccio, A., Genre, A., Pieterse, C.M.J., Bonfante, P., Van der Heijden, M.G.A. (2013). Arbuscular mycorrhizal fungi reduce growth and infect roots of the non-host plant Arabidopsis thaliana. Plant Cell Environ. 36: 1926-1937. 94. Ponzio, C., Gols, R., Pieterse, C.M.J. and Dicke, M. (2013). Ecological and phytohormonal aspects of plant volatile emission in response to single and dual infestations with herbivores and phytopathogens. Functional Ecology 27: 587-598. 95. Pineda, A., Dicke, M., Pieterse, C.M.J. and Pozo, M.J. (2013). Beneficial microbes in a changing environment: are they always helping plants to deal with insects? Functional Ecology 27: 574-586. 96. Giron, D., Frago, E., Glevarec, G., Pieterse, C.M.J. and Dicke, M. (2013). Cytokinins as key regulators in plant microbe insect interactions: connecting plant growth and defence. Functional Ecology 27: 599-609. 97. Bakker, P.A.H.M., Berendsen, R.L., Doornbos, R.F., Wintermans, P.C.A. and Pieterse, C.M.J. (2013). The rhizospere revisited: root microbiomics. Frontiers in Plant Science 4: 165. 98. Vos, I.A., Pieterse, C.M.J. and Van Wees, S.C.M. (2013). Costs and benefits of hormone-regulated plant defences. Plant Pathology 62: 43-55. 99. Pangesti, N., Pineda, A., Pieterse, C.M.J., Dicke, M. and Van Loon, J.J.A. (2013). Two-way plant mediated interactions between root-associated microbes and insects: from ecology to mechanisms. Frontiers in Plant Science 4: 414. 100. Pieterse, C.M.J., Poelman, E.H., Van Wees, S.C.M. and Dicke, M. (2013). Induced plant responses to microbes and insects. Frontiers in Plant Science 4: 475. 101. Vos, I.A., Verhage, A., Schuurink, R.C., Watt, L.G., Pieterse, C.M.J. and Van Wees, S.C.M. (2013). Onset of herbivore-induced resistance in systemic tissue primed for jasmonate-dependent defenses is activated by abscisic acid. Frontiers in Plant Science 4: 539. 102. Cuéllar Pérez, A., Nagels Durand, A., Vanden Bossche, R., De Clercq, R., Persiau, G., Van Wees, S.C.M., Pieterse, C.M.J., Gevaert, K., De Jaeger, G., Goossens, A. and Pauwels, L. (2014). The Non-JAZ TIFY protein TIFY8 from Arabidopsis thaliana is a transcriptional repressor. PLoS ONE 9: e84891. 103. Arseneault, T., Pieterse, C.M.J., Gérin-Ouellet, M., Goyer, C. and Fillion, M. (2014). Long-term induction of defense gene expression in potato by Pseudomonas sp. LBUM223 and Streptomyces scabies. Phytopathology, 104: 926-932. 104. Pieterse, C.M.J., Zamioudis, C., Berendsen, R.L., Weller, D.M., Van Wees, S.C.M. and Bakker, P.A.H.M. (2014). Induced systemic resistance by beneficial microbes. Annual Review of Phytopathology, 52: 347-375. 105. Luna, E., Van Hulten, M., Zhang, Y., Berkowitz, O., López, A., Pétriacq, P., Sellwood, M.A., Chen, B., Burrell, M., Van de Meene, A., Pieterse, C.M.J., Flors, V. and Ton, J. (2014). Plant perception of β- aminobutyric acid is mediated by an aspartyl-trna synthetase. Nature Chemical Biology 10: 450-456. 106. Zamioudis, C., Hanson, J. and Pieterse, C.M.J. (2014). ß-Glucosidase BGLU42 is a MYB72-dependent key regulator of rhizobacteria-induced systemic resistance and modulates iron deficiency responses in Arabidopsis roots. New Phytologist, 204:368-379. 107. Pel, M.J.C., Van Dijken, A.J.H., Bardoel, B.W., Seidl, M.F., Van der Ent, S., Van Strijp, J.A.G. and Pieterse, C.M.J. (2014). Pseudomonas syringae evades host immunity by degrading flagellin monomers with alkaline protease AprA. Molecular Plant-Microbe Interactions 27: 603-610. 108. Pieterse, C.M.J., Pierik, R. and Van Wees, S.C.M. (2014). Different shades of JAZ during growth and defense. New Phytologist 204: 261-264. 109. Pel, M.J.C., Wintermans, P.C.A., Cabral, A., Robroek, B.J.M., Seidl, M.F., Bautor, J., Parker, J.E., Van den Ackerveken, G. and Pieterse, C.M.J. (2014). Functional analysis of Hyaloperonospora arabidopsidis RXLR effectors. PLoS ONE 9: e110624. 110. Caarls, L., Pieterse, C.M.J. and Van Wees, S.C.M. (2015). How salicylic acid takes transcriptional control over jasmonic acid signalling. Frontiers in Plant Science 6: 170. 111. Berendsen, R.L., Van Verk, M.C., Stringlis, I.A., Zamioudis, C., Tommassen, J., Pieterse, C.M.J. and Bakker, P.A.H.M. (2015). Unearthing the genomes of plant-beneficial Pseudomonas model strains WCS358, WCS374 and WCS417. BMC Genomics 16: 539. 112. Zamioudis, C., Korteland J., Van Pelt, J.A., Van Hamersveld, M., Dombrowski, N., Bai, Y., Hanson, J., Van Verk, M.C., Ling, H.-Q., Schulze-Lefert, P., and Pieterse, C.M.J. (2015). Rhizobacterial volatiles and photosynthesis-related signals coordinate MYB72 in Arabidopsis roots during onset of induced systemic resistance and iron deficiency responses. Plant Journal 84: 308-322. 19/31

113. Broekgaarden, C., Caarls, L., Vos, I.A., Pieterse, C.M.J. and Van Wees, S.C.M. (2015). Ethylene: traffic controller on hormonal crossroads to defense. Plant Physiology 169: 2371-2379 114. Vos, I.A., Moritz, L., Pieterse, C.M.J. and Van Wees, S.C.M. (2015). Impact of hormonal crosstalk on plant resistance and fitness under multi-attacker conditions. Frontiers in Plant Science 6: 639. 115. Mithoe, S.C., Ludwig, C., Pel, J.J.C., Cucinotta, M., Casartelli, A., Mbengue, M., Sklenar, J., Derbyshire, P., Robatzek, S., Pieterse, C.M.J., Aebersold, R. and Menke, F.L.H. (2016). Attenuation of pattern recognition receptor signaling is mediated by a MAP kinase kinase kinase. EMBO Reports 17:441 454. 116. Pieterse, C.M.J., de Jonge, R. and Berendsen, R.L. (2016). The soil-borne supremacy. Trends in Plant Science 21: 171-173. 117. Wintermans, P.W.A., Bakker, P.A.H.M. and Pieterse, C.M.J. (2016). Natural genetic variation in Arabidopsis for responsiveness to plant growth-promoting rhizobacteria. Plant Molecular Biology 90: 623-634. 118. Coolen, S., Proietti, S., Hickman, R., Davila Olivas, N.H., Huang, P.-P., Van Verk, M.C., Van Pelt, J.A., Wittenberg, A.H.J., De Vos, M., Prins, M., Van Loon, J.J.A., Aarts, M.G.M., Dicke, M., Pieterse, C.M.J. and Van Wees, S.C.M. (2016). Transcriptome dynamics of Arabidopsis during sequential biotic and abiotic stresses. Plant Journal 00: 000-000. 119. Davila Olivas, N.H., Coolen, S., Huang, P.-P.., Severing, E., Van Verk, M.C., Hickman, R., Wittenberg, A.H.J., De Vos, M., Prins, M., Van Loon, J.J.A., Aarts, M.G.M., Van Wees, S.C.M., Pieterse, C.M.J. and Dicke, M. (2016). Effect of prior drought and pathogen stress on Arabidopsis transcriptome changes to caterpillar herbivory. New Phytologist 00: 000-000. Contributions to books and proceedings (in chronological order) 1. Pieterse, C.M.J. and Koornneef, M. (1988). Optimization of direct gene transfer in tomato. In: K.J. Puite, J.J.M. Dons, H.J. Huizing, A.J. Kool, M. Koornneef and F.A. Krens (eds.), "Progress in Plant Protoplast Research". Kluwer Academic Publishers, Dordrecht, pp. 357-358. 2. Govers, F., Franssen, H.J., Pieterse, C.M.J., Wilmer, J. and Bisseling, T. (1990). Function and regulation of the early nodulin gene ENOD2. In: G.W. Lycett and D. Grierson (eds.), "Genetic Engineering of Crop Plants". Butterworths, London, pp. 259-269. 3. Pieterse, C.M.J. and Davidse, L.C. (1990). Attempted cloning of the Phytophthora infestans pyr-gene for use in a homologous transformation system. Phytophthora Newsletter 16: 7-8. 4. Pieterse, C.M.J. and Govers, F. (1990). Recente ontwikkelingen in het moleculair genetisch onderzoek aan plant-pathogeen interacties. Gewasbescherming 22: 46-47. 5. Pieterse, C.M.J., Risseeuw, E.P. and Davidse, L.C. (1991). An in planta induced gene of Phytophthora infestans codes for ubiquitin. In: H. Hennecke and D.P.S. Verma (eds.), "Advances in Molecular Genetics of Plant-Microbe Interactions", vol. 1. Kluwer Acacemic Publishers, Dordrecht, pp. 272-275. 6. Govers, F. and Pieterse, C.M.J. (1993). List of cloned genes in Phytophthora infestans. Phytophthora Newsletter 19: 1. 7. Pieterse, C.M.J. (1993). Differential gene expression in Phytophthora infestans during pathogenesis on potato. Ph.D. Thesis, Wageningen Agricultural University. 8. Hoffland, E., Pieterse, C.M.J., Bik, L. and Van Pelt, J.A. (1995). Induced resistance in Arabidopsis and radish; involvement of PR proteins. In: Proceedings of the 3rd Conference on "Environmental Biotic Factors in Integrated Plant Disease Control", September 5-9 1994, Poznań, Poland, pp. 265-268. 9. Pieterse, C.M.J., Van Wees, S.C.M., Van Pelt, J.A., Trijssenaar, A., Van 't Westende, Y.A.M., Bolink, E.M. and Van Loon, L.C. (1996). Systemic resistance in Arabidopsis thaliana induced by biocontrol bacteria. Mededelingen van de Faculteit Landbouwkundige en Toegepaste Biologische Wetenschappen, Universiteit Gent 61/2a: 209-220.V 10. Van Loon, L.C., Bakker, P.A.H.M. and Pieterse, C.M.J. (1997). Mechanisms of PGPR-induced resistance against pathogens. In: Proceedings of the 4th International Workshop on "Plant Growth-Promoting Rhizobacteria", Japan-OECS Joint Workshop, October 5-10 1997, Sapporo, Japan, pp. 50-57. 11. Govers, F., Drenth, A. and Pieterse, C.M.J. (1997). The potato late blight pathogen Phytophthora infestans and other pathogenic oomycota. In: Carroll and Tudzynski (eds.), "The Mycota Volume V Part B: Plant Relationships". Springer-Verlag, Berlin, pp. 17-36. 20/31

12. Pieterse, C.M.J., Van Wees, S.C.M., Van Pelt, J.A. and Van Loon, L.C. (1998). A novel defence pathway in Arabidopsis induced by biocontrol bacteria. Mededelingen van de Faculteit Landbouwkundige en Toegepaste Biologische Wetenschappen, Universiteit Gent 63/3b: 931-940. 13. Van Loon, L.C., Bakker, P.A.H.M. and Pieterse, C.M.J. (1998). Induction and expression of PGPR-mediated induced resistance against pathogens. In: Molecular Approaches to Biological Control (B.K. Duffy, U. Rosenberger and G. Défago, eds), IOBC/wprs Bulletin 21(9): 103-110. 14. Ton, J., Pieterse, C.M.J. and Van Loon, L.C. (1998). Genetic analysis of induced systemic resistance in Arabidopsis thaliana: association between induced and basal resistance. In: Molecular Approaches to Biological Control (B.K. Duffy, U. Rosenberger and G. Défago, eds), IOBC/wprs Bulletin 21(9): 111-115. 15. Pieterse, C.M.J., Van Wees, S.C.M., Ton, J., Léon-Kloosterziel, K.M., Van Pelt, J.A., Keurentjes, J.J.B., Knoester, M. and Van Loon, L.C. (2000). Rhizobacteria-mediated induced systemic resistance (ISR) in Arabidopsis: involvement of jasmonate and ethylene. In: Biology of Plant-Microbe Interactions, Volume 2 (P.J.G.M. De Wit, T. Bisseling and W.J. Stiekema, eds), The International Society for Molecular Plant- Microbe Interactions, St. Paul, MN., pp. 291-296. 16. Hase, S., Pieterse, C.M.J. and Van Loon, L.C. (2001). Mechanisms of rhizobacteria-mediated induced systemic resistance. In: Recognition and Signal Transduction in Plant-Microbe Interactions (T. Teraoka, ed), PSJ Plant-Microbe Interactions Symposium Report 37, pp. 15-24. Yamanashi, Japan. 17. Léon-Kloosterziel, K.M., Verhagen, B.W.M., Keurentjes, J.J.B., Van Loon, L.C. and Pieterse, C.M.J. (2002). Identification of genes involved in rhizobacteria-mediated induced systemic resistance in Arabidopsis. In: Induced Resistance in Plants against Insects and Diseases (I. Baldwin, M. Dicke, E. Haukioja, B. Mauch-Mani and A. Schmitt, eds), IOBC/wprs Bulletin 25(6): 71-74. 18. Pieterse, C.M.J., Spoel, S., Ton, J., Van Wees, S.C.M., Van Pelt, J.A. and Van Loon, L.C. (2002). Crosstalk between salicylate- and jasmonate-dependent induced defences in Arabidopsis. In: Biology of Plant- Microbe Interactions, Volume 3 (S.A. Leong, C. Allen and E.W. Triplett, eds), The International Society for Molecular Plant-Microbe Interactions, St. Paul, MN, pp. 107-112. 19. Pieterse, C.M.J., Ton, J., Van Wees, S.C.M., Hase, S., Léon-Kloosterziel, K.M., Verhagen, B.W.M., Van Pelt, J.A. and Van Loon, L.C. (2002). Rhizobacteria-mediated induced systemic resistance in Arabidopsis. In: Induced Resistance in Plants Against Insects and Diseases (I. Baldwin, M. Dicke, E. Haukioja, B. Mauch-Mani and A. Schmitt, eds), IOBC/wprs Bulletin 25(6): 9-16. 20. Ton, J., De Vos, M., Robben, C., Van Pelt, J.A., Van Loon, L.C. and Pieterse, C.M.J. (2002). Induced resistance: an enhancement of basal resistance? In: Induced Resistance in Plants Against Insects and Diseases (I. Baldwin, M. Dicke, E., Haukioja, B. Mauch-Mani and A. Schmitt, eds), IOBC/wprs Bulletin 25(6): 133-138. 21. Van Loon, L.C. and Pieterse, C.M.J. (2002). Biocontrol agents in signalling resistance. In: Biological Control of Crop Diseases (Gnanamanickam, S.S., ed), Marcel Dekker, New York, NY, pp. 355-386. 22. Van Loon, L.C., Bakker, P.A.H.M. and Pieterse, C.M.J. (2002). Prospects and challenges for practical application of rhizobacteria-mediated induced systemic resistance. In: Induced Resistance in Plants Against Insects and Diseases (I. Baldwin, M. Dicke, E. Haukioja, B. Mauch-Mani and A. Schmitt, eds), IOBC/wprs Bulletin 25(6): 75-82. 23. Van Oosten, V.R., De Vos, M., Van Pelt, J.A., Van Loon, L.C., Van Poecke, R.M.P., Dicke, M. and Pieterse, C.M.J. (2004). Signal signature of Arabidopsis induced upon pathogen and insect attack. In: Biology of Plant-Microbe Interactions, Volume 4 (I. Tikhonovich, B. Lugtenberg and N. Provorov, eds.), The International Society for Molecular Plant-Microbe Interactions, St. Paul, MN, pp. 199-202. 24. De Vos, M., Van Oosten, V.R., Van Pelt, J.A., Van Loon, L.C., Dicke, M. and Pieterse, C.M.J. (2004). Herbivore-induced resistance: differential effectiveness against a set of microbial pathogens in Arabidopsis thaliana. In: Biology of Plant-Microbe Interactions, Vol. 4 (I. Tikhonovich, B. Lugtenberg, N. Provorov, eds.), The International Society for Molecular Plant-Microbe Interactions, St. Paul, MN, pp. 40-43. 25. Pieterse, C.M.J., Bakker, P.A.H.M., Verhagen, B.W.M. and Van Loon, L.C. (2004). Signaling during rhizobacteria-induced systemic resistance in Arabidopsis. In: Biology of Plant-Microbe Interactions, Volume 4 (I. Tikhonovich, B. Lugtenberg and N. Provorov, eds.), The International Society for Molecular Plant-Microbe Interactions, St. Paul, MN, pp. 192-195. 26. Pozo, M.J., Van Loon, L.C. and Pieterse, C.M.J. (2004). Boosting plant defence by beneficial soil microorganisms. In: Proceedings of the 16 th Workshop of Marie Curie Fellows: Research Training in Progress, Petten (Netherlands), 21-22 October, 2003, pp. 158-161. 27. Pieterse, C.M.J., Van Pelt, J.A., Van Wees, S.C.M., Ton, J., Verhagen, B.W.M., Léon-Kloosterziel, K., Hase, S., De Vos, M., Van Oosten, V., Pozo, M., Spoel, S., Van der Ent, S., Koornneef, A. and Van 21/31

Loon, L.C. (2004). Rhizobacteria-induced systemic resistance and pathway cross talk to fine-tune defense. In: Proceedings of 2 nd Brasilian Meeting on Induced Resistance in Plants, 9-11 November 2004, University of Lavras, Lavras, Brazil, p. 44-58. 28. Pieterse, C.M.J. (2005). Netwerken met signalen - Het immuunsysteem van planten. Oratie Universiteit Utrecht, 35 p. 29. Pieterse, C.M.J., Schaller, A., Mauch-Mani, B. and Conrath, U. (2006). Signalling in plant resistance responses: divergence and cross-talk of defence pathways. In: Multigenic and Induced Systemic Resistance in Plants (S. Tuzun and E. Bent, eds), Springer, New York, pp. 166-198. 30. Pieterse, C.M.J., Van Pelt, J.A., Verhagen, B.W.M., De Vos, M., Van Oosten, V.R., Van der Ent, S., Koorneef, A., Van Hulten, M.H.A., Pozo, M.J., Ton, J., Dicke, M. and Van Loon, L.C. (2006). Molecular mechanisms involved in induced resistance signaling in Arabidopsis. In: Biology of Molecular Plant- Microbe Interactions, Vol. 5 (F. Sánchez, C. Quinto, I.M. López-Lara and O. Geiger, eds.), The International Society for Molecular Plant-Microbe Interactions, St. Paul, MN, pp. 188-194. 31. Spoel, S.H., Mou, Z., Zhang, X., Pieterse, C.M.J. and Dong, X. (2006). Regulatory roles of NPR1 in plant defense: regulation and function. In: Biology of Molecular Plant-Microbe Interactions, Vol. 5 (F. Sanchez, C. Quinto, I.M. Lopez-Lara and O. Geiger, eds), The International Society for Molecular Plant-Microbe Interactions, St. Paul, MN., pp. 182-187. 32. Ton, J., Pieterse, C.M.J. and Van Loon, L.C. (2006). The relationship between basal and induced resistance in Arabidopsis. In: Multigenic and Induced Systemic Resistance in Plants (S. Tuzun and E. Bent, eds), Springer, New York, pp. 197-224. 33. Van der Ent, S., Pozo, M.J., Verhagen, B.W.M., Bakker, D., Van Loon, L.C. and Pieterse, C.M.J. (2006). Identification of transcription factors in roots and shoots of Arabidopsis that are involved in rhizobacteria-induced systemic resistance. In: Multitrophic Interactions in Soil and Integrated Control (J.M. Raaijmakers and R.A. Sikora, eds), IOBC/wprs Bulletin 29(2): 157-161. 34. Verhagen, B.W.M., Van Loon, L.C. and Pieterse, C.M.J. (2006). Induced disease resistance signaling in plants. In: Floriculture, Ornamental and Plant Biotechnology, Vol III (J.A. Teixeira da Silva, ed), Global Science Books, pp. 334-343. 35. Pieterse, C.M.J. and Van Loon, L.C. (2007). Signalling cascades in induced resistance. In: Induced Resistance for Plant Defence: A Sustainable Approach to Crop Protection (D. Walters, A. Newton and G. Lyon, eds), Blackwell, Oxford, UK, pp. 65-88. 36. Pieterse, C.M.J., Van der Ent, S., Van Pelt, J.A. and Van Loon, L.C. (2007). The role of ethylene in rhizobacteria-induced systemic resistance (ISR). In: Advances in Plant Ethylene Research: Proceedings of the 7th International Symposium on the Plant Hormone Ethylene (Ramira, A., Chang, C., Giovannoni, J., Klee, H., Perata, P., and Woltering, E., eds), Springer, Dordrecht, the Netherlands, pp. 325-331. 37. Ton, J., Van der Ent, S., Van Hulten, M., Pozo, M., Van Oosten, V., Van Loon, L.C., Mauch-Mani, B., Turlings, T.C.J. and Pieterse, C.M.J. (2008). Priming as a mechanism behind induced resistance against pathogens, insects and abiotic stress. In: Breeding for Inducible Resistance Against Pests and Diseases (B. Mauch-Mani, M. Dicke, A. Schmidt, eds), IOBC/wprs Bulletin, pp. 000-00. 38. Pieterse, C.M.J., Koornneef, A., Léon Reyes, A., Ritsema, T., Verhage, A., Joosten, R., De Vos, M., Van Oosten, V. and Dicke, M. (2008). Cross-talk between signaling pathways leading to defense against pathogens and insects. In: Biology of Molecular Plant-Microbe Interactions, Vol. 6 (M. Lorito, S. Woo and F. Scala, eds), International Society for Molecular Plant-Microbe Interactions, St. Paul, MN., pp. 1-9. 39. Verhage, A., De Vos, M., Dicke, M. and Pieterse, C.M.J. (2008). The transcription factor AtMYC2 shapes plant defense responses in Arabidopsis upon Pieris rapae herbivory. In: Biology of Molecular Plant- Microbe Interactions, Vol. 6 (M. Lorito, S. Woo and F. Scala, eds), The International Society for Molecular Plant-Microbe Interactions, St. Paul, MN., pp. 1-6. 40. Van Pelt, J.A,, Van der Sluis, I., Pieterse, C.M.J., and Bakker P.AH.M. (2008). Induced Systemic Resistance Bioassays in Arabidopsis thaliana. In: Prospects and Applications for Plant-Associated Microbes. A Laboratory Manual, Part A: Bacteria. (S. Sorvari and A. M. Pirttilä, Eds.). BioBien Innovations, Piikkiö, Finland, pp. 113-118. 41. Bakker, P.A.H.M., Van Pelt, J.A., Van der Sluis, I., and Pieterse, C.M.J. (2008). Bacterial elicitors and plant signaling in induced systemic resistance. In: Prospects and Applications for Plant-Associated Microbes. A Laboratory Manual, Part A: Bacteria. (S. Sorvari and A. M. Pirttilä, Eds.). BioBien Innovations, Piikkiö, Finland, pp. 276-282. 22/31

42. Van der Ent, S., Koornneef, A., Ton, J. and Pieterse, C.M.J. (2009). Induced resistance - orchestrating defence mechanisms through cross-talk and priming. In: Annual Plant Reviews - Molecular Aspects of Plant Disease Resistance (J.E. Parker, ed), Blackwell, pp. 334-370. 43. Van Hulten, M., Ton, J., Pieterse, C.M.J. and Van Wees, S.C.M. (2010). Plant defense signaling from the underground primes aboveground defenses to confer enhanced resistance in a cost-efficient manner. In: Plant Communication from an Ecological Perspective; Signaling and Communication in Plants (F. Baluska, V. Ninkovic, eds), Springer-Verlag Berlin Heidelberg, pp. 43-60 44. Van der Ent, S. and Pieterse, C.M.J. (2012). Ethylene: multitasker in plant-attacker interactions. In: Annual Plant Reviews - The Plant Hormone Ethylene (M.T. McManus, ed). Blackwell Publishing. Annual Plant Reviews 44: 343-377. 45. Pieterse, C.M.J., Leon-Reyes, A., Van der Does, D., Verhage, A., Koornneef, A., Van Pelt, J.A. and Van Wees, S.C.M. (2012). Networking by small-molecule hormones in plant immunity. In: Induced resistance in plants against insects and diseases, IOBC-WPRS Bulletin 83: 77-80. 46. Van Wees, S.C.M., Van Pelt, J.A., Bakker, P.A.H.M. and Pieterse, C.M.J. (2013). Bioassays for assessing jasmonate-dependent defenses triggered by pathogens, herbivorous Insects, or beneficial rhizobacteria. In: Jasmonate Signaling - Methods and Protocols (eds. A. Goossens and Laurens Pauwels). Methods in Molecular Biology 1011: 35-49. 47. Pieterse, C.M.J., Zamioudis, C., Van der Does, D. and Van Wees, S.C.M. (2014). Signalling networks involved in induced resistance. In: Induced Resistance for Plant Defence: A Sustainable Approach to Crop Protection (D.R. Walters, A.C. Newton and G.D. Lyon, eds), Wiley-Blackwell, Oxford, UK, pp. 65-88. 48. Pieterse, C.M.J. and Van Wees, S.C.M. (2015). Induced disease resistance. In: Principles of Plant-Microbe Interactions: Microbes for Sustainable Agriculture (B. Lugtenberg (ed)). Springer, pp. 123-133. Patent applications 1. Ton, J., Van der Ent, S., Van Hulten, M.H.A., Pieterse, C.M.J. (2007). Defense priming in plants. Patent application PCT/NL2007/050472 (filed 28 September 2007). 2. Bardoel, B.W., Kessel, K., Van der Ent, S., and Pieterse, C.M.J., and Van Strijp, J. (2009). Use of Pseudomonas aeruginosa alkaline protease (AprA) and inhibitors thereof in medicine and agriculture. Patent application PCT/EP2009/053758 Abstracts for international meetings: >180 Invited lectures (in chronological order) 1. An in planta induced gene of Phytophthora infestans codes for ubiquitin. 5 th International Congress of "Molecular Plant-Microbe Interactions", Interlaken, Switzerland (1990). 2. Cloning of in planta induced genes of Phytophthora infestans: an approach to unravel the molecular mechanism underlying pathogenicity of P. infestans. MOGEN Seminars, Mogen, Leiden, NL (1990). 3. Molecular aspects of the potato-phytophthora infestans interaction. International Symposium on "Advances in Potato Crop Protection", Wageningen, NL (1991). 4. Characterization of the putative pathogenicity genes ipio2a and ipio2b of Phytophthora infestans. 24 th Lunteren Lectures on "Signal Transduction in Microorganisms and Plants", Lunteren, NL (1992). 5. Arabidopsis as a model system to study systemic resistance induced by plant growth-promoting rhizobacteria. Seminar Department of Biology, University of Zurich, Zurich, Switzerland (1995). 6. Arabidopsis as a model system to study systemic resistance induced by plant growth-promoting rhizobacteria. 4 th International Arabidopsis Network Meeting, El Escorial, Spain, (1995). 7. Systemic resistance in Arabidopsis thaliana induced by biocontrol bacteria. 48 th International Symposium on Crop Protection, Gent, Belgium (1996). 8. Systemic resistance in Arabidopsis thaliana induced by biocontrol bacteria. SLW meeting Moleculaire Celbiologie van Planten, Wageningen, NL (1996). 9. A novel signalling pathway controlling induced disease resistance in Arabidopsis. 5 th International Congress of "Plant Molecular Biology", Singapore (1997). 10. A novel signalling pathway controlling induced resistance in Arabidopsis. Willie Commelin-Scholten Symposium, Utrecht, NL (1997). 23/31

11. A novel signalling pathway controlling induced resistance in Arabidopsis. ARANED meeting, Utrecht, NL (1997). 12. Rhizobacteria-mediated induced systemic resistance in Arabidopsis. Seminar Rhône-Poulenc, Lyon, France (1997). 13. Biocontrol bacteria-mediated induced systemic resistance in Arabidopsis. European Union Meeting, Madrid, Spain (1997). 14. A novel signalling pathway controlling induced resistance in Arabidopsis. Meeting with the International Advisory Board of the Graduate School of Experimental Plant Sciences, Wageningen, NL (1997). 15. Pathways controlling long distance signalling: Induced systemic resistance (ISR) and systemic acquired resistance (SAR). PhD Summer School Disease Resistance in Plants, Wageningen, NL (1998). 16. A novel signalling pathway controlling induced systemic resistance in Arabidopsis. 9 th International Conference on Arabidopsis Research, Madison, USA (1998). 17. A novel defence pathway induced by biocontrol bacteria in Arabidopsis. 50 th International Symposium on Crop Protection, Gent, Belgium (1998). 18. Systemische resistentie in Arabidopsis geïnduceerd door Pseudomonas fluorescens bacteriën verloopt via een nieuw ontdekte signaaltransductieroute. Gewasbescherminsmanifestatie, Wageningen, NL (1998). 19. Mechanisms of induced resistance in plants. Studiekring Plantenveredeling, Wageningen, NL (1998). 20. Ethylene- and jasmonate-dependent signalling during induced systemic resistance (ISR) in Arabidopsis. 9 th International Congress of Molecular Plant-Microbe Interactions, Amsterdam, NL (1999). 21. Rhizobacteria-mediated induced systemic resistance in Arabidopsis. Seminar Department of Biology, University of Fribourg, Switzerland (1999). 22. Ethylene- and jasmonate-dependent signalling during induced systemic resistance (ISR) in Arabidopsis. European Union Meeting, Norwich, UK (1999). 23. Rhizobacteria-mediated induced systemic resistance: triggering, signalling and expression. 1 st International Symposium Induced Resistance to Plant Diseases, Corfu, Greece (2000). 24. Rhizobacteria-mediated induced systemic resistance: triggering, signalling and expression. Seminar Max- Planck-Institute for Plant Breeding Research, Cologne, Germany (2000). 25. Enhancement of induced resistance by simultaneous activation of salicylate- and jasmonate-dependent defence pathways in Arabidopsis thaliana. International Symposium on Durable Resistance, Ede- Wageningen, NL (2000). 26. Mechanisms of induced defences in plant-pathogen interactions. Autumnschool Interactions Between Plants and Attacking Organisms, Wageningen University, NL (2000). 27. Enhancement of induced resistance by simultaneous activation of salicylate- and jasmonate-dependent defence pathways in Arabidopsis. European Union Meeting, Villars-sur-Ollon, Switzerland (2000). 28. Induced systemic resistance in Arabidopsis. European Union Meeting, Enkhuizen, NL (2000). 29. Ethylene and jasmonate signalling in induced systemic resistance. 17 th International Conference on Plant Growth Substances, Brno, Czech Republic (2001). 30. Cross-talk between jasmonate- and salicylate-dependent induced defences in Arabidopsis. EPS Summerschool Environmental Signalling: Arabidopsis as a Model, Utrecht, NL (2001). 31. Cross-talk between induced defence pathways in Arabidopsis. NWO-ALW Meeting Experimental Plant Sciences, Lunteren, NL (2001). 32. Cross-talk between jasmonate-and salicylate-dependent induced defences. 10 th International Congress on Molecular Plant-Microbe Interactions, Madison, USA (2001). 33. Rhizobacteria-mediated induced systemic resistance in Arabidopsis. 6 th International Workshop on Pathogenesis-Related Proteins in Plants, Spa, Belgium (2001). 34. Rhizobacteria-induced systemic resistance in Arabidopsis. 1 st IOBC/wprs Conference on Induced Resistance in Plants against Insects and Diseases, Wageningen, NL (2001). 35. Cross-talk between plant defence pathways. Three-yearly retreat of the Plant Research Laboratory, Michigan State University, East Lansing, Michigan, USA (2001). 36. Cross-talk between plant defence signalling pathways. ARANED Meeting, Utrecht, NL (2002). 37. Induced systemic resistance by plant growth-promoting rhizobacteria. 9 th International Symposium on Nitrogen Fixation with Non-Legumes, Leuven, Belgium (2002). 38. Systemic defence against pathogens. Summerschool Ecophysiology of Plants, Midlaren, NL (2002). 39. Rhizobacteria-mediated induced systemic resistance. National Meeting on Mechanisms of Plant Defence, Sendai, Japan (2002). 40. Induction of systemic resistance by root-zone bacteria: from perception to expression of resistance. 8 th 24/31

International Congress of Plant Pathology, Christchurch, New Zealand (2003). 41. Geïnduceerde resistentie: een kwestie van prioriteiten stellen. Gewasbeschermingsdag van de Koninklijke Nederlandse Plantenziektekundige Vereniging, Wageningen, NL (2003). 42. Defence-related secundary metabolites in induced resistance in Arabidopsis. 13 th Symposium Secundair Metabolisme in Plant en Plantencel, Utrecht, NL (2003). 43. Induced plant defense: signaling and expression of resistance. Summerschool Molecular Basis of Plant- Microbe Interactions, Leiden University, NL (2003). 44. Cross-communication between plant defence pathways. NWO-ALW Meeting Experimental Plant Sciences, Lunteren, NL (2003). 45. Plant innate immunity: signals chat to make a choice. Seminar at Department of Plant Molecular Biology, Gene Expression Laboratory, University of Lausanne, Switzerland (2003). 46. Plant innate immunity: signals chat to make a choice. Seminar at the Department of Molecular Biology, Institute for Botany, University of Bonn, Germany (2003). 47. Plant innate immunity: triggered to treat the threat. Seminar at Department of Plant Survival, University of Neuchatel, Switzerland (2003). 48. Plant innate immunity. Seminar at the Faculty of Veterinary Sciences, Utrecht University, NL (2004). 49. Rhizobacteria-induced systemic resistance and pathway cross talk to fine-tune defense. International Joint Workshop on PR-Proteins and Induced Resistance", Elsinore, Denmark (May 2004). 50. Plant innate immunity: cross-talk between signaling pathways to fine-tune defense. Seminar during theme symposium Strategies and mechanisms to suppress phytopathogens of the KNBV Jaarvergadering, Wageningen University, NL (2004). 51. Rhizobacteria-induced systemic resistance and pathway cross talk to fine-tune defense. Seminar at the Botanical Institute, University of Basel, Switzerland (2004). 52. Rhizobacteria-induced systemic resistance and pathways cross-talk to fine-tune defense. Seminar at ESALQ, University of Sao Paulo, Piracicaba, Brazil (2004). 53. Rhizobacteria-induced systemic resistance and pathways cross-talk to fine-tune defense. 2 nd Brasilian Meeting on Induced Resistance in Plants, University of Lavras, Lavras, Brazil (2004). 54. Rhizobacteria-induced systemic resistance and pathways cross-talk to fine-tune defense. EU-BIORHIZ Workshop on Direct Interactions in the Rhizosphere, 17-19 January 2005, Wageningen, NL (2005). 55. Induced resistance signaling. Albrecht-von-Haller-Institute, University of Göttingen, Germany (2005). 56. Induced resistance signaling in Arabidopsis. Seminar at Max-Planck-Institute for Chemical Ecology, Jena, Germany (2005). 57. Plant self defense. Summerschool on Ecophysiology of Plants, Midlaren, NL (2005). 58. Molecular mechanisms of induced resistance signaling in Arabidopsis. International Congress on Molecular Plant-Microbe Interactions, Merida, Mexico (December 2005). 59. Signaling during induced plant defense. Seminar at University of Granada, Spain (April 2006) 60. Arabidopsis as a model to study PGPR-ISR. 7 th International Workshop on Plant Growth-Promoting Rhizobacteria, Noordwijkerhout, NL (April 2006). 61. The role of ethylene in induced disease resistance. International Congress on the plant hormone Ethylene, Pisa, Italy (May 2006). 62. Signaling during induced systemic resistance in Arabidopsis. Symposium on Signal Exchange Between Roots and Microorganisms, 7-9 March, 2007, Göttingen, Germany 63. Unraveling natural plant defense signaling networks. Workshop on Ecophysiology of Plants, Midlaren, NL, December 13, 2007. 64. Unraveling natural plant defense signaling networks using (eco)genomics. Seminar at Institute for Water and Wetland Research, Nijmegen, NL, October 16, 2007. 65. Cross-talk between defense signaling pathways. Summerschool Environmental Signaling: Arabidopsis as a Model. Utrecht, NL, August 27-29, 2007. 66. Cross-talk between defense signaling pathways. 13 th International Congress on Molecular Plant-Microbe Interactions. Sorrento, Italy, July 21-27, 2007. 67. Ecogenomics to study plant-attacker interactions: from genes to ecology or from ecology to genes? Ecogenomics meeting, Ede, NL, February 29, 2008. 68. Cross-talk between salicylic acid and jasmonic acid defense signaling. Keystone Symposium on Plant Innate Immunity and Plant Hormones and Signaling, Keystone, USA, 10-15 February, 2008. 69. Cross-talk between pathogen and insect defense signaling. International Conference on Biotic Plant Interactions, Brisbane, Australia, 27-29 March 2008. 25/31

70. Changes in hostile environments: signaling makes sense. Symposium Institute of Environmental Biology, Utrecht University, NL, 27 October 2008. 71. Exploring the plant s natural defense response. 3 rd Workshop on Plant-insect interactions, Leiden University, NL, 29 October 2008. 72. Non-pathogenic rhizobacteria-induced systemic resistance: effects on insect herbivores and their natural enemies. Current Themes in Ecology, Wageningen University, NL, 11 November 2008. 73. Defense signaling from the underground. University of Göttingen, Germany, 2 December 2008. 74. Plant immune responses triggered by beneficial microorganisms. 46 th Congress of the South African Society of Plant Pathology, Cape Town, South Africa, 25-28 January 2009. 75. Uncovering novel mechanisms of pathogen-induced suppression of host defense signaling in the plant immune system. Summit of the Centre for BioSystems Genomics, Wageningen, NL, 17 March 2009. 76. Networking by small-molecule hormones in plant defense. 5 th IOBC meeting on Induced Resistance against Pathogens and Insects, Granada, Spain, 12-16 May 2009. 77. Networking by small-molecule hormones in plant immunity. 20 th International Conference on Arabidopsis Research, Edinburgh, UK, 30 June -4 July 2009. 78. Networking by small-molecule hormones in plant defense. NWO-ALW platform Molecular Genetics, Lunteren, NL, 16 October 2009. 79. Making sense out of signaling during plant defense: an ecogenomics approach. Ecogenomics Symposium, Amsterdam, NL, 21 April 2010. 80. The plant immune system. Symposium on Microbial-Associated Molecular Patterns in Plants: Plant Hormone Responses, Salamanca, Spain, 25-26 February 2010. 81. Networking by small-molecular hormones in plant immunity. Gordon Research Conference on Plant Molecular Biology, Holderness, USA, 18-23 July 2010. 82. Plant immunity by beneficial microbes. Symposium of the American Phytopathological Society and the Molecular Phytopathological Society, Nashville, Tennessee, USA, 7-11 August 2010. 83. Hormonal crosstalk in plant immunity. Rothamsted Research Institute, Harpenden, UK, 21 September 2010. 84. Plant immunity: it s the hormones talking, but what do they say? Institute Seminar VIB Plant Systems Biology, University of Ghent, 12 October 2010, Ghent, Belgium. 85. Plant immunity: it s the hormones talking, but what do they say? Institute Seminar University of Paris- Nord, 4 November 2010, Paris, France. 86. Plant immunity: it s the hormones talking, but what do they say? EPS Summerschool on Ecophysiology, 18 November 2010, Midlaren, the Netherlands. 87. Hoe planten zich verweren tegen microorganismen. Seminar HOVO, University of Leiden, 23 November 2010, Leiden, the Netherlands. 88. Zelfverdediging bij planten. Artemis studiedag. 9 November 2011, Berkel en Rodenrijs, NL. 89. Making sense out of signaling during plant defense. International symposium on PR-proteins and induced resistance against pathogens and insects. 4-8 September 2011, Neuchatel, Switzerland. 90. Modulation of plant immunity by beneficial and parasitic organisms in Arabidopsis. European Science Foundation workshop on Plant-microbe-insect interactions, Wageningen, NL. 18-20 August 2011. 91. Plant immunity: It s the hormones talking, but what do they say? Institute seminar University of Edinburgh, Edinburgh, UK. 27 June 2011. 92. Exploring and exploiting the plant immune system. Seminar BEJO Seeds, Warmerhuizen, NL. 7 June 2011. 93. Mining natural genetic variation of combinatorial stress responses of Arabidopsis to identify new tolerance pathways for biotic and abiotic stress. STW Perspective meeting Learning from nature to protect crops, Wageningen, NL. 94. Plant immunity: It s the hormones talking, but what do they say? 10th IMPRS Symposium, Jena, Germany. 7 February 2011. 95. Plant immunity: It s the hormones talking, but what do they say? EPS Theme 2 Symposium/Willie Commelin Scholtenday, Amsterdam, NL. 3 February 2011. 96. Microbial modulation of the plant immune system. Microbiology Seminars, Utrecht University, NL. 31 January 2012. 97. Zelfverdediging bij planten. Plant Health group. Utrecht, NL. 17 February 2012. 98. Defense systems in plants. Plant Health Care, Oisterwijk, NL. 28 February 2012. 26/31

99. Plant responses to beneficial soil-borne microbes. Mycorrhiza Ecology Symposium, Utrecht, NL. 25 January 2012. 100. Zelfverdediging bij planten. Study group Plant Health, Utrecht University, Utrecht, NL. 17 February 2012. 101. Defense systems in plants. Plant Health Care meeting, Oisterwijk, NL. 28 February 2012. 102. Modulation of host immunity by beneficial microbes. Institute Seminar University of Giessen, Germany. 2 March 2012. 103. Plant immunity: a matter of hormones. Institute Seminar Instituto de Tecnologia Química e Biológica, Lisbon, Portugal. 20 April 2012. 104. Networking by small-molecule hormones in plant immunity. Bijvoet Retreat, Soesterberg, NL. 24 April 2012. 105. Plant immunity: it s the hormones talking but what do they say? Institute Seminar Free University of Amsterdam, Amsterdam, NL. 15 May 2012. 106. Hormonal modulation of plant immunity. Institute Seminar Max Planck Institute, Cologne, Germany, 20 June 2012. 107. Hormonal modulation of plant immunity. Congress of Society of Experimental Biology (SEB), Salzburg, Austria, 29 June 2012. 108. Hormonal modulation of plant immunity. International Symposium on Molecular Plant-Microbe Interactions, Kyoto, Japan, 31 July 2012. 109. Induceerbaar weerbaar. Leerbaar Weerbaar Workshop, Delft, the Netherlands. 18 September 2012. 110. Induced resistance: a matter of hormones. VI Brazilian Meeting on Induced Resistance in Plants against Pathogens, Viçosa, Brazil. 19 November 2012. 111. Trade-offs and benefits of hormonal modulation of plant immunity. British Society of Plant Pathology Conference on fitness costs, Norwich, UK, 17 December 2012. 112. Hormonal modulation of plant immunity. Institute seminar Leuven University, Belgium. 23 January 2013. 113. Plant protection and environmental change. Plant Science and Climate Change symposium, Utrecht, the Netherlands, 22 May 2013. 114. Hormonal modulation of plant immunity. Top lecture Leiden University, the Netherlands. 23 May 2013. 115. Hormonal modulation of plant immunity. Institute Seminar RWTH Aachen University, Aachen, Germany, 20 June 2013. 116. Modulation of host immunity by beneficial microbes. Institute Seminar Korea Research Institute of Bioscience & Biotechnology, Daejeong, South Korea, 22 August 2013. 117. Hormonal modulation of plant immunity. Institute Seminar National Institute of Agricultural Science and Technology, Suwon, South Korea, 22 August 2013. 118. The roots of rhizobacteria-induced systemic resistance. 10th International Congress on Plant Pathology, Beijng, China, 30August 2013. 119. Plant immunity: hormonal modulation of the plant s social network. Institute Seminar CINVESTAV, Irapuato, Mexico, 19 November 2013. 120. Hormonal modulation of plant immunity: shaping the plant s social network. 32nd New Phytologist Symposium on Plant interactions with other organisms: molecules, ecology and evolution, 20 November 2013, Buenos Aires, Argentina. 121. Het immuunsysteem van planten. Seminar High School Nieuwegein, 2 October 2013, Nieuwegein, NL. 122. Leerbaar weerbaar: het immuunsysteem van planten. KNAW sectie Biologie, 27 January 2014, Amsterdam, NL. 123. Het wortelmicrobioom en plantgezondheid. KNAW afdeling Natuurkunde, 24 February 2014, Amsterdam, NL. 124. Hormonal modulation of plant immunity. 16th International Congress on Molecular Plant-Microbe Interactions, Rhodes, Greece. 6-10 July 2014. 125. The roots of rhizobacteria-induced systemic resistance. 2nd Latin American Workshop on Plant Growth Promoting Rhizobacteria, La Falda, Argentina. 21-26 September 2014. 126. De nieuwe kleren van de plant: keizerlijk chemisch harnas klaar voor de strijd. Lezing Utrechtse Biologen Vereniging, Utrecht, 30 October 2014. 127. Modulation of host immunity by the root microbiome. CRC 973 Symposium Bridging Ecology and Molecular Biology: Organismic Responses to Recurring Stress, Berlin, Germany, 18-20 February 2015. 128. Hormonal communication in the plant s social network. Institute seminar University of Munich, Germany, 30 April 2015. 27/31

129. Modulation of plant stress responses by beneficial microbes. 2015 Interdisciplinary Plant Group Symposium Plants Between a Rock and a Hard Place: The Interface Between Abiotic and Biotic Stress Responses, University of Missouri, Columbia, USA, 27-29 May 2015. 130. Ruftende bacteriën voor weerbare plant. NWO Bessensap, Den Haag, the Netherlands, 12 June 2015. 131. The root of rhizobacteria-induced systemic resistance (ISR), Rhizosphere4, Maastricht, the Netherlands, 21-24 June 2015. 132. The root of rhizobacteria-induced systemic resistance (ISR). PRIR-2015 International Symposium on PR Proteins and Induced Resistance against Pathogens and Insects, RWTH Aachen University, Germany, 6-10 September 2015. 133. The root microbiome and plant health. ENVIRON conference Environmental adaptation: from molecules to the planet, Tartu, Estonia, 1-3 October 2015. 134. The plant microbiome and plant health. Keygene lecture, Wageningen, the Netherlands, 2 October 2015. 135. Plantweerbaarheid tot op de bodem uitgezocht. Kennisdebat Groene Gewasbescherming, Rijswijk, the Netherlands, 29 October 2015. 136. Hormonal modulation of plant immunity. ENZA Zaden lecture, Enkhuizen, the Netherlands, 11 November 2015. 137. The root microbiome and plant immunity. Meeting KNVM, Utrecht, the Netherlands, 13 November 2015. 138. Interface between plant breeding and microbiome functioning. Nanjing University meeting, Utrecht, the Netherlands, 16 November 2015. 139. The root microbiome and plant health. Current Themes in Ecology, Lunteren, the Netherlands, 19 November 2015. 140. The root microbioma and plant health. Koppert B.V., Berkel en Rodenrijs, the Netherlands, 1 December 2015. 141. Het immuunsysteem van planten. Lezing Studium Generale Universiteit Utrecht, the Netherlands, 16 February 2016. 142. Hormonal modulation of the plant s social network. Institute Seminar University of Helsinki, Finland, 16 March, 2016. 143. Plantendokter. Meet the Professor, Highschool in De Meern, the Netherlands, 30 March 2016. 144. Ruftende bacteriën voor weerbare plant. Culturele Zondag, Utrecht, the Netherlands, 3 April 2016. 145. Fungi in the root microbiome and plant health. CBS symposium Fungi and Global Challenges, Amsterdam, 15 April 2016. 146. The plant microbiome and plant health, University of Sheffield, UK, 21 April 2016. 147. Hormonal modulation of the plant s social network. Institute Seminar University of Lausanne, Switzerland, 28 April 2016. 148. The root microbiome and plant health, Helmholtz Centre Munich, Germany, 3 May 2016. 28/31

ACQUISITION OF FUNDING PLANT-MICROBE INTERACTIONS GROUP In the past years, acquisition of external funding for the PMI group reached a total of >12 M. We aim for a healthy mix of funding for fundamental research and more applied research. In the past 10 years, 55% of the funding was for fundamental research (6,5 M ) and 45% for more applied research (5,5 M ranging from STW funding to direct funding by industry). Grants obtained since 2001 2016-2020 Industry (300 k ; to Guido van den Ackveken): Modifiers of dmr6/dlo1-mediated disease resistance. 2015-2020 STW Perspective Programme Back to the Roots (3 M for total programme, Pieterse/Bakker co-applicants with NIOO, WUR, and LU). Funding for UU 583 k : Innovation by nature: plant traits involved in maximizing growth and protective functions of root microbiota (2 PhD projects). 2015-2020 STW Perspective Programme LED it be 50% (Van Wees with Pierik; 250k PhD project) 2015-2017 Marie Curie Fellowship (to Ivan Fernandez-Lopez): Molecular dialogue in antagonistic versus mutualistic mycorrhizal networks (200 k ). 2015-2019 NWO MSc Talent Programme Tuinbouw & Uitgangsmaterialen Getting to the root of it: boosting plant health by beneficial root microbes (250 k ; Pieterse with Eline Verbon). 2015-2018 STW-VENI Elucidating the immune signalling regulatory network in Arabidopsis thaliana with digital genomic footprinting (250 k to Richard Hickman). 2014-2017 STW-VENI Outsmarting the attacker: New strategies to protect crops against manipulative insects (250 k to Colette Broekgaarden). 2014-2017 STW-VENI Lectin receptor kinases; novel leads for disease resistance in crop plants (250 k to Klaas Bouwmeester). 2014-2018 STW Perspective Programme Green Defenses Against Pests project Plant-thrips interactions: uncovering dynamics of the plant defence signalling network to identify novel leads for maximizing crop protection (528 k ; Pieterse with Dicke, WUR). 2014-2020 STW Perspective Programme Green Defenses Against Pests (3 M for total programme, Pieterse co-applicant with UvA, WUR, LU, and RUN). 2014-2017 NWO Open Competition project Molecular dialogue in antagonistic versus mutualistic mycorrhizal networks (250 k ; Pieterse with Van der Heijden) 2013-2017 NWO Meer met Minder project Dissecting oomycete-induced immunity in Arabidopsis deploying a non-toxic NEP1-like protein as PAMP (250 k ; Van den Ackerveken) 2013-2017 TKI-U project Topsector Tuinbouw & Uitgangsmaterialen Strategic breeding for resistance to downy mildew by monitoring and deploying pathogen effector genes (800 k ; Van den Ackerveken, with 4 plant breeding companies). 2013-2017 STW open technology programme "Effectors and their plant targets as leads for downy mildew resistance breeding in lettuce" (850 k ; Van den Ackerveken with co-applicant WUR). 2013-2015 Marie Curie Fellowship (to Silvia Proietti): Networking by stress signalling pathways: identification of novel regulators of combinatorial stress tolerance (200 k ). 2012-2014 Marie Curie Fellowship (to Ainhoa Martinez-Mecina): Induced Resistance in tomato by beneficial microorganisms - Translating Arabidopsis-derived molecular knowledge on defense signalling (200 k ). 2012 Centre for BioSystems Genomics (CBSG): Exploring the plant s innate immune system: uncovering novel mechanisms of pathogen-induced suppression of host defense (50 k extension grant - Pieterse). 2011-2016 STW-VIDI (to Saskia van Wees): Networking hormones in plant immunity: an ecological and a systems approach to make sense out of defense signalingplant immunity: cross-talk between signaling pathways to fine-tune defense (800 k ). 2011-2016 ERC Advanced Investigator Grant (Pieterse): The Plant Immune System: a multidisciplinary approach to uncover how plants simultaneously deal with beneficial and parasitic organisms to maximize profits and protection (2.5 M ). 29/31

2010-2014: National STW Perspective Research Program Learning from nature to protect crops of the Dutch Technology Foundation (6,5 M ; Pieterse with Wageningen University partners coapplicant of the program). 2010-2014 STW Perspective: Mining natural genetic variation of combinatorial stress responses of Arabidopsis to identify new tolerance pathways for biotic and abiotic stress (1 M ; Pieterse with Wageningen University and companies KeyGene, Genetwister, and Royal Van Zanten). 2010-2015 Industry (to Guido van den Ackveken): Functional analysis of Arabidopsis downy mildew resistance genes (560 k ). 2008-2012 Centre for BioSystems Genomics (CBSG): Exploring the plant s innate immune system: uncovering novel mechanisms of pathogen-induced suppression of host defense (250 k ; Pieterse). 2008-2012 UU: Molecular mechanisms of priming for enhanced defense (40 k ; Pieterse) 2008-2012 CBSG: Oomycete effectors stimulating plant disease susceptibility (250 k ; Van den Ackerveken). 2007-2011 Top Institute Green Genetics: Novel approaches for resistance breeding using pathogen effectors and their host targets: towards durable resistance to Bremia in lettuce (400 k ; Van den Ackerveken) 2007-2010 ERA-Plant Genomics: Understanding host plant susceptibility and resistance by indexing and deploying obligate pathogen effectors (250 k ; Van den Ackerveken). 2007-2008 CBSG: Priming for enhanced resistance to (a)biotic stress: large scale profiling of transcription factor gene expression to finger print the primed state (50 k ; Pieterse). 2006-2011 STW: Control of Verticillium fungicola on mushroom (600 k, Bakker with Microbiol.-UU). 2006-2010 Top Institute Pharma: Novel kinases involved in cancer-relevant processes (269 k ; Pieterse). 2006-2010 Industry: Functional analysis of Arabidopsis downy mildew resistance genes (560 k ; Van den Ackerveken). 2004-2011 NWO-VICI and UU: Plant immunity: cross-talk between signaling pathways to fine-tune defense (1.25 M ; Pieterse). 2004-2008 SenterNovem innovational subsidy: Controlled regulation of broad-spectrum resistance in plants (320 k ; Pieterse in collaboration with companies GeneTwister, Royal Van Zanten, Vitrocom). 2004-2008 CBSG: Priming of defense gene expression in plant-oomycete interactions (200 k ; Pieterse). 2002-2006 NWO-ALW Open Competition grant: Analysis of the cytosolic function of NPR1 in crosscommunication between SA- and JA-dependent defense signaling (200 k ; Pieterse). 2001-2006: NWO-ALW Open Competition grant: Crosstalk between signal-transduction pathways in induced defence of Arabidopsis against microbial pathogens and herbivorous insects (200 k ; Pieterse with Dicke, WUR). 2001-2005 UU-National Graduate School EPS: Effectiveness of insect-induced resistance against microbial pathogens in Arabidopsis (160 k ; Pieterse). RELEVANT WEBSITES Personal webpage: http://www.uu.nl/staff/cmjpieterse/0 Plant-Microbe Interactions group: http://www.uu.nl/en/research/plant-microbe-interactions Institute of Environmental Biology: http://www.uu.nl/en/research/institute-of-environmental-biology Department of Biology: http://www.uu.nl/en/organisation/department-of-biology 30/31

Faculty of Science: http://www.uu.nl/en/organisation/faculty-of-science Utrecht University: http://www.uu.nl UU focus area Future Food Utrecht http://www.uu.nl/en/research/future-food-utrecht Utrecht Graduate School of Life Sciences: http://www.uu.nl/university/education/en/graduateschools/gsls/pages/default.aspx?refer=/lifesciences Master s programme Environmental Biology: http://students.uu.nl/en/gsls-life-sciences/environmental-biology PhD programme Environmental Biology: http://www.uu.nl/en/education/graduate-school-of-life-sciences/phd/environmental-biology Dutch PhD Graduate School Experimental Plant Sciences: http://www.graduateschool-eps.info/index.php 31/31