InternatIonal JOURNAL OF ANATOMY PHYSIOLOGY and BIOCHEMISTRY



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ORIGINAL RESEARCH ARTICLE http://www.eternalpublication.com InternatIonal JOURNAL OF ANATOMY PHYSIOLOGY and BIOCHEMISTRY IJAPB: Volume: 1; Issue: 1; October 2014 ISSN(Online):2394-3440 A Morphometric Study of the Vertebral Body in Dry Human Typical Thoracic Vertebrae Published online on 14 th October 2014 www.eternalpublication.com DR. PATIL DHAVAL K. 1 DR. BHUIYAN PRITHA S. 2 1 Assistant Professor, GMC, Miraj 2 Professor and HOD, Department of Anatomy, Seth G S Medical College, Parel, Mumbai, Maharashtra, India Corresponding Author: Dr. Dhaval K. Patil Assistant Professor 3, Nandanvan, Plot no. 444, Sai Section, Ambarnath-421501, Maharashtra, India +91 9869611917 drdhavalpatil@gmail.com Received: 6 th Oct 2014; Accepted: 11 th Oct 2014 How to cite this article: A Morphometric Study of the Vertebral Body in Dry Human Typical Thoracic Vertebrae. International Journal of Anatomy Physiology and Biochemistry 2014; 1(1):24-28. Abstract: Background: Majority of studies in the past aboutmorphometry of thoracic vertebrae mainly focused on pedicle diameters and their angulations. The vertebral body were not studied or only little importance was given to them. Taking into account the complex nature of thoracic spine, the present has given importance to the morphometry of vertebral body. Objective: To measure the various dimensions of vertebral body in typical thoracic vertebrae. Material and methods: Two hundred dry human typical thoracic vertebrae of undetermined gender and age were selected for the. The various parameters of vertebral body were measured. Results: The anteroposterior distance of the vertebral body in typical thoracic vertebrae ranged from 12.36-31.26 mm with a mean of 20.78 ± 3.36 mm. The transverse diameter of the vertebral body ranged from 22.16-35.52 mm with a mean of 27.02 ± 2.06 mm. The vertebral body width ranged from 20.36-47.76 mm with a mean of 25.49 ± 2.59 mm. The anterior height of the body ranged from 12.16-24.72 mm with a mean of 17.17 ± 1.65 mm. The posterior height of the body ranged from 14.04-26.28 mm with a mean of 18.27 ± 1.64 mm. Conclusion: The results provide a comprehensive database for more accurate modelling and design of vertebral body implants and instrumentations for Indian population. Key Words:, Anterior height, Posterior height, Vertebral body width, Typical thoracic vertebra Introduction: The adult vertebral column (also called the spine or spinal column) usually consists of 33 vertebral segments- 7 cervical, 12 thoracic, 5 lumbar, 5 sacral and 4 coccygeal. The linkages between the vertebrae include cartilaginous interbody joints and paired synovial facet (zygapophysial) joints, together with a complex of ligaments and overlying muscles and fasciae. The functions of the column are to support the trunk, to protect the spinal cord and nerves, and to provide attachments for muscles. It is also an important site of haematopoiesis throughout life. 1 The vertebrae can be involved in various conditions. These include fractures, infections, malignancies and inflammatory disorders. Abnormal curvatures of the vertebral column in the thoracic region such as kyphosis and scoliosis may result from developmental anomalies or pathological processes involving vertebrae. 2 The vertebral bodies and the intervertebral discs form an important column in transmission of weight of the Morphometric Study of the Body of Typical Thoracic Vertebrae (Page 24-28) 24

body. In the upper thoracic region, due to the anterior curvature, the main part of the compressive force is transmitted through the anterior column formed vertebral body and intervertebral disc, with resulting increased stress. 3 The compressive force in the lower thoracic region is transmitted through two parallel columns, one anterior and one posterior formed by successive articulations of laminae with each other. 4 In recent years, there have been considerable developments in instrumentation designed to stabilize and correct the thoracic spine. 5 Anterior interbody fusion, in association with a variety of methods to stabilize both the implant and motion segment, has increased in popularity. Also, expandable vertebral body replacement material is being used to provide solid anterior column constructs with restoration of height and sagittal alignment. The anterior route provides direct access to most spine diseases and allows optimal neural decompression and the possibility of adequate realignment and strong reconstruction/fixation. Stability of the vertebral column is achieved, resolution of clinical pain is rapid and almost complete, and the rate of surgical complications is very low. Hence, the present measured the various dimensions of vertebral body. 1. Anteroposterior distance of the vertebral body- It is the distance between anterior border and posterior border of the superior surface of vertebral body in midline. (Fig. 3) 2. Transverse diameter of the vertebral body- It is the maximum transverse diameter of the vertebral body at the superior surface. 3. Vertebral body width- It is the minimum transverse distance across the sides of vertebra in anterior view of the body. (Fig. 4) 4. Anterior height of the body- It is the vertical distance between superior and inferior surface of body in the midline anteriorly. (Fig. 5) 5. Posterior height of the body- It is the vertical distance between superior and inferior surface of body in the midline posteriorly. Material and Methods: The was conducted on dry human typical thoracic vertebrae. The vertebrae were obtained from the bone collection of the department of Anatomy of a tertiary care hospital. Of the total collection of thoracic vertebrae in the department, 200 undamaged typical thoracic vertebrae were selected for the. The vertebrae were of undetermined gender and age. Each vertebra was assigned a serial number. Anatomical measurements were taken on these specimens using a verniercaliper (0-150mm with a precision of 0.02 (Fig. 1-5). The following parameters were recorded in a proforma: Fig.1- Illustration showing measurement of the anteroposterior distance and transverse diameter in typical thoracic vertebra. Fig.2- Illustration showing measurement of anterior and posterior height of the body in typical thoracic vertebra. Morphometric Study of the Body of Typical Thoracic Vertebrae (Page 24-28) 25

Fig. 3- Illustration showing measurement of anteroposterior distance of the vertebral body Fig. 4- Illustration showing measurement of vertebral body width 3. The vertebral body width in typical thoracic vertebrae ranged from 20.36-47.76 mm with a mean of 25.49 ± 2.59 mm. 4. The anterior height of the body in typical thoracic vertebrae ranged from 12.16-24.72 mm with a mean of 17.17 ± 1.65 mm. 5. The posterior height of the body in typical thoracic vertebrae ranged from 14.04-26.28 mm with a mean of 18.27 ± 1.64 mm. Discussion: Several quantitative anatomical studies have been carried out for thoracic vertebrae in different countries. Many authors have studied the vertebrae using different methods such as plain radiographs, direct specimen measurements and quantitative 3- dimensional anatomic techniques. These include Panjabi MM et al 6, Tan et al 7, Roop Singh et, Gupta R et al 9 and Kunkel ME et al 10. However, Berry JL et al 11 studied only second and seventh thoracic vertebrae. The following tables present the comparison of means of the various parameters obtained from previous studies with that of the present. Fig. 5- Illustration showing measurement of anterior height of the body Results: 1. The anteroposterior distance of the vertebral body in typical thoracic vertebrae ranged from 12.36-31.26 mm with a mean of 20.78 ± 3.36 mm. 2. The transverse diameter of the vertebral body in typical thoracic vertebrae ranged from 22.16-35.52 mm with a mean of 27.02 ± 2.06 mm. Table 1: Comparison of mean anteroposterior distance of the vertebral body in typical thoracic vertebrae with other for Panjabi 1991 USA Dry bones 24.26 MM et al 6 Tan et al 7 2004 Singapore Dry bones 20.21 2014 Indian Dry bones 20.78 When compared, the meananteroposterior distance of the vertebral body in the present is lesser than the value found by Panjabi MM et al 6 but is in agreement with the finding of Tan et al 7. Morphometric Study of the Body of Typical Thoracic Vertebrae (Page 24-28) 26

Table 2: Comparison of mean transverse diameter of the vertebral body in typical thoracic vertebrae with other for Panjabi MM 1991 USA Dry bones 26.06 et al 6 Tan et al 7 2004 Singapore Dry bones 23.84 Singh R et 2011 India Dry bones 25.9 2014 India Dry bones 27.02 The mean transverse diameter of the vertebral body in the present is slightly greater that of the earlier Table 3: Comparison of mean vertebral body width in typical thoracic vertebrae with other for Berry JL et 1987 USA Dry bones 28.05 al 11 Gupta R et al 9 2011 India Dry bones 27.62 Singh R et 2011 India Dry bones 24.88 2014 India Dry bones 25.49 According to Table 3, the value of mean vertebral body width in the present issimilar to that of Singh R et but lesser than that of the other Gupta R et al 9 mention that the vertebral body width ranged between 19.06-39.39 mm for typical thoracic vertebrae as compared to 20.36-47.76 mm in the present. Table 4: Comparison of mean anterior height of the body in typical thoracic vertebrae with other for Tan et al 7 2004 Singapore Dry bones 15.04 Singh R et 2011 India Dry bones 17.39 Kunkel ME 2011 Germany Cadaveric, 15.84 et al 10 Radiographic 2014 India Dry bones 17.17 The mean anterior height of the body in the present is in agreement with the results of by Singh R et and is greater than the values reported by Tan et al 7 and Kunkel ME et al 10. Table 5: Comparison of mean posterior height of the body in typical thoracic vertebrae with other for Berry JL 1987 USA Dry bones 17.8 et al 11 Panjabi 1991 USA Dry bones 16.86 MM et al 6 Tan et al 7 2004 Singapore Dry bones 16.41 Singh R et 2011 India Dry bones 18.19 Kunkel 2011 Germany Cadaveric, 17.99 ME et al 10 Radiographic 2014 India Dry bones 18.27 The finding in the present is nearly equal to that of Singh R et, Kunkel ME et al 10 and Berry JL et al 11 but is slightly greater than Panjabi MM et al 6 and Tan et al 7. Singh R et found that the anterior height was less as compared to posterior height of body at all levels of thoracic spine. They noted this as an explanation for the normal physiological kyphosis present in the thoracic region. The present found a similar observation. Morphometric Study of the Body of Typical Thoracic Vertebrae (Page 24-28) 27

Conclusion: Thus, a comprehensive data set has been presented which provides quantitative anatomy of vertebral body of typical thoracic vertebrae. The differences in the results of the present and those of the previous studies with respect to some of the parameters may be due to differences in race, ethnicity, environmental factors as well as methods used for the These findings strengthen the recommendations by Roop Singh et for modification in spinal surgery instrumentations in accordance with the morphometric data obtained from Indian population. In the future, the scope of the can be further extended to the vertebral column with respect to individual vertebral levels. Acknowledgements: 1. Dean, Seth G. S. Medical College and K.E.M. Hospital, Mumbai 2. Department of Anatomy, Seth G. S. Medical College, Mumbai References: 1. Standring S. et al. The Back. In: Newell RL, editor. Gray s Anatomy: Anatomical Basis of Clinical Practice. 40th ed. Edinburgh: Elsevier Churchill Livingstone; 2008: 712-724. 2. Snell RS. Clinical Anatomy by Systems. Philadelphia: Wolters Kluwer Health- Lippincott Williams & Wilkins; 2006:170 3. Pal GP, Routal RV. A of weight transmission through the cervical and upper thoracic regions of the vertebral column in man. Journal of Anatomy 1986; 148:245-261. 4. Pal GP, Routal RV. Transmission of weight through the lower thoracic and lumbar regions of the vertebral column in man. Journal of Anatomy 1987; 152:93-105. 5. Chaynes P, Sol JC, Vaysse P, Bécue J, Lagarrigue J. Vertebral pedicle anatomy in relation to pedicle screw fixation: a cadaver. SurgRadiolAnat 2001; 23:85-90. 6. Panjabi MM, Takata K, Goel V, Federico D, Oxland T, Duranceau J, et al. Thoracic human vertebrae: quantitative threedimensional anatomy. Spine (Phila Pa 1976) 1991; 16:888-901. 7. Tan SH, Teo EC, Chua HC. Quantitative three-dimensional anatomy of cervical, thoracic and lumbar vertebrae of Chinese Singaporeans. Eur Spine J 2004;13:137-146 8. Singh R, Srivastva S, Prasath C, Rohilla R, Siwach R, Magu N. Morphometric measurements of cadaveric thoracic spine in Indian population and its clinical applications. Asian Spine J 2011; 5(1):20-34. 9. Gupta R, Singla RK. Thoracolumbar neural canal - a morphometric and morphological in North Indian population. J Pharm Biomed Sci 2011; 11(11):1-7. 10. Kunkel M E, Herkommer A, Reinehr M, Böckers T M, Wilke HJ. Morphometric analysis of the relationships between intervertebral disc and vertebral body heights: an anatomical and radiographic of the human thoracic spine. J Anat 2011; 219:375-380. 11. Berry JL, Moran JM, Berg WS, Steffee AD. A morphometric of human lumbar and selected thoracic vertebrae. Spine (Phila Pa 1976) 1987; 12:362-367. Morphometric Study of the Body of Typical Thoracic Vertebrae (Page 24-28) 28