Sergio O. Martínez Curriculum Vitae

Sergio O. Martínez Curriculum Vitae Professor of the Electrical and Computer Engineering Departament at Tecnológico de Monterrey, Monterrey Campus, México. Researcher and chair of the Sensors and Devices area at the National School of Engineering and Sciences, Tecnológico de Monterrey, México. Founder and leader of the Biointeractive Systems and BioMEMS research group. Member of the Mexican Academy of Sciences Member of the Mexican Research National System Founding Member of Lambda-Rho Chapter of Etta-Kappa-Nu Senior Member of IEEE, Member of SPIE and OSA EDUCATION Ph.D. in Microelectronics, National Polytechnic Institute, Grenoble, France, May 2002. M.S. in Electronics, Philips International Institute, Eindhoven, The Netherlands, May 1990. M.S. in Control Engineering, Tecnológico de Monterrey, Monterrey, Mexico, December 1985. B.S. in Electronics and Communications Eng, Tecnológico de Monterrey, Monterrey, Mexico, May 1983. ACADEMIC CAREER (TECNOLÓGICO DE MONTERREY) Chair of the Sensors and Devices Research Area, since July 2014. Chair of the Electrical and Computer Engineering Department, Jan 2004-Jun 2014. Principal Investigator of the Biointeractive Systems and BioMEMS Research group, since Jan 2005. Professor of Electrical and Computer Engineering, since Nov 1997. Associate Professor of Electrical and Computer Engineering, from May 1991 to Nov 1997. Assistance Professor of Electrical and Computer Engineering, from Jan 1986 to May 1991. Teaching Assistant of Electrical and Computer Engineering, from Jan 1984 to Dec 1985. Sergio O. Martínez 1

BIOGRAPHICAL SKETCH Sergio O. Martinez is professor of the Electrical and Computer Engineering Department at Tecnológico de Monterrey, Monterrey Campus; and researcher and chair of the Sensors and Devices area of the National School of Engineering and Sciences at the same Institute, where he has worked for 30 years. He is founder and leader of the Biointeractive Systems and BioMEMS research group. Sergio O. Martínez received the B.S. degree in Electronics and Communications Engineering and the M.S. degree in Control Engineering both from Tecnológico de Monterrey, Campus Monterrey, México in 1983 and 1985, respectively. He obtained a M.S. degree in Electronics from Philips International Institute, Eindhoven, Netherlands in 1990; and the Ph.D. degree in Microelectronics from National Polytechnic Institute of Grenoble, France in 2002. In 1984, Sergio O. Martínez joined the Electrical and Computer Engineering Department at Tecnológico de Monterrey, Campus Monterrey where he was appointed Associate Professor and Professor in 1991 and 1997 respectively. In 2002, he started research activities on BioMEMS, and since 2005, he is Principal Investigator of the Biointeractive Systems and BioMEMS Research Chair. Sergio O. Martínez is member of the Mexican Research National System since 2004 and the Mexican Academy of Sciences since 2010. His recent research activities, focused on BioMEMS and Microelectronics, include Modeling and Implementation of Electrokinetically-driven Microfluidic Devices, CMOS-based/SPR-based Biosensing Platforms, and Carbon-MEMS. He is or has been Principal Investigator in projects funded by CONACYT, the Mexican Economy Ministry, and the Bureau of Science and Technology of Nuevo Leon. He has authored/coauthored 65 peer-reviewed publications, 5 book chapters and 1 granted patent. He has supervised 31 Master thesis and 7 PhD thesis. From 2002 to 2007, Sergio O. Martínez has introduced new courses in the undergraduate and graduate programs in Electronics at Tecnológico de Monterrey: CMOS Microelectronics, Microsystems, Digital Integrated Systems, Bioinstrumentation, and BioMEMS. In 2004, he founded the Microelectronics and MEMS Design Lab fostering training and research activities on these subjects, and in 2014 he founded the Microfabrication and Microfluidics Lab. In 2004, he was appointed department head of Electrical and Computer Engineering, a position that hold until June 2014, when he was appointed chair of the Sensors and Devices area at the National School of Engineering and Sciences. His academic leadership at Tecnológico de Monterrey has been awarded with Rómulo Garza Prize for Research and Technology Development in 2009, and the Teaching and Research Award in 2007 and 2010. Sergio O. Martínez 2

SIGNIFICANT ACHIEVEMENTS AND AWARDS Chair of the Sensors and Devices research area at the National School of Engineering and Sciences, Tecnológico de Monterrey, July 2014. Senior Member of IEEE, April 2013. Award to the Professor who left a Mark, from the Community of Former Students of Tecnológico de Monterrey, May 2013. Member of Etta-Kappa-Nu, Electrical and Computer Engineering Honor Society of IEEE, May 2013. Award from the College of Mechanical, Electrical and Electronics Engineering of Nuevo León, Jun 2012. Member of the Mexican Academy of Sciences, Oct 2010 to present. Teaching & Research Award, ITESM, Monterrey Campus, May 2010. Rómulo Garza Research & Development Award, Computer evaluation of hydrogel-based systems for Diabetes closed loop treatment, Jan 2009. Member of the Mexican Research National System, Jan 2004 Dec 2008, Jan 2009 to present. Teaching & Research Award, ITESM, Monterrey Campus, May 2007. Founder and Principal Investigator of the Biointeractive Systems and BioMEMS Group at ITESM, Jan 2005 to present. Award to the Engaged Professor from the Federation of Students of Tecnológico de Monterrey, Apr 2005. Founder of the Microelectronics and MEMS Lab at Tecnologico de Monterrey, 2004. Advisor of 31 Master thesis and 7 PhD thesis. Author/Coauthor of 64 peer-reviewed publications, 5 book chapters, and 1 granted patent. Sergio O. Martínez 3

JOURNAL PAPERS [2014] 16. A. Losoya, M. Estevez, S. Martínez, L. Lechuga, "Design of a Surface Plasmon Resonance Immunoassay for Therapeutic Drug Monitoring of Amikacin.", submitted to Analytical and Bioanalytical Chemistry. [2013] 15. A. Salazar, S. Camacho, O. Rossetto, S. Martínez, "Towards a SPR-based Biosensing Platform incorporating a CMOS Active Column Sensor", Analog Integrated Circuits and Signal Processing, vol. 77, pp. 365-372, 2013. 14. V. Perez, V. Ho, L. Kulinsky, M. Madou, S. Martínez, "PPyDEP: A new approach to microparticle manipulation employing polymer-based electrodes", Lab on a Chip, vol. 13, no. 23, pp. 4642-4652, 2013. 13. M. Lopez, H. Moncada, V. Perez, B. Lapizco, S. Martínez, "An Electric Stimulation System for Electrokinetic Particle Manipulation in Microfluidic Devices", Review of Scientific Instruments, vol. 84, 035103, 2013. [2012] 12. A. Losoya, S. Camacho, G. Dieck, S. Martínez, "State of the Art and New Perspectives in Non-Invasive Glucose Sensors", Revista Mexicana de Ingeniería Biomédica, vol. 33, no. 1, pp. 41-52, 2012. [2011] 11. S. Camacho, S. Martínez, A. Elias, G. Dieck, "Parameterized layout synthesis of a CMOS-compatible scanning micromirror with electrothermal actuation and bimodal resonant behavior", e-gnosis, vol. 9, no. 10, pp. 1-18, 2011. [2010] 10. M. Lemiszka, G. Dieck, S. Martínez, J. Garza, Modelación del nivel de ácido láctico para atletas de alto rendimiento, Revista Mexicana de Ingeniería Biomédica, vol. 31, no. 1, pp. 41-56, 2010. 9. M. Lemiszka, G. Dieck, S. Martínez, J. Garza, Modelación dinámica de lactato en isquemia para atletas de alto rendimiento, Revista Mexicana de Ingeniería Biomédica, vol. 31, no. 1, pp. 57-72, 2010. [2009] 8. J. Baylón, B. Lapizco, C. Reyes, A. Chávez, S. Martínez, Prediction of trapping zones in an Insulatorbased dielectrophoretic device, Lab on a Chip, vol. 9, no. 20, pp. 2896-2901, 2009. 7. I. Sánchez, R. Morales, S. Martínez, Glucose optimal control system in Diabetes treatment, Applied Mathematics and Computation, vol. 209, pp. 19-30, 2009. 6. J. Martínez, H. Moncada, J. Baylón, S. Martínez, M. Rito, B. Lapizco, Characterization of electrokinetic mobility of microparticles in order to improve dielectrophoretic concentration, Analytical and Bioanalytical Chemistry, vol. 394, pp. 293-302, 2009. [2008] 5. R. Martínez, S. Cito, E. Collado, S. Martínez, M. Madou, Fluido-Dynamic and Electromagnetic Characterization of 3D Carbon Dielectrophoresis with Finite Element Analysis, Sensors and Transducers Journal, vol. 3, pp. 25-36, 2008. Sergio O. Martínez 4

4. S. Ozuna, B. Lapizco, M. Rito, S. Martínez, C. Reyes, Performance characterization of an insulatorbased dielectrophoretic microdevice, Electrophoresis, vol 29, no 15, pp: 3115-3122, 2008. 3. I. Sánchez, S. Martínez, N. Peppas, Computer evaluation of hydrogel-based systems for Diabetes closed loop treatment, AIChE Journal, vol. 54, no.7, pp. 1901-1911, 2008. [2007] 2. S. Ozuna, B. Lapizco, M. Rito, E. Collado, S. Martínez, Insulator-based dielectrophoresis, Revista Mexicana de Ingeniería Química, vol. 6, no. 3, pp. 329-335, 2007. [2005] 1. A. Molina, H. Ahuett, J. Cortés, G. Jiménez, M. Ramírez, C. Rodríguez, S. Martínez, Next generation manufacturing systems: key research issues in developing and integrating reconfigurable and intelligent machines, International Journal of Computer Integrated Manufacturing, vol. 18, no. 7, pp. 525-536, 2005. CONFERENCE PAPERS [2014] 54. M. Vazquez, J. Hernandez, S. Camacho, R. Gallo, J. Santana, S. Martínez, A Comparative Study of AC Electroosmotic Micropumps By Computational Modeling of Non-Equilibrium Electrokinetics, submitted to the 14th AICHE Annual Meeting, Atlanta, GA, USA, 16-21 Nov, 2014. 53. R. Gallo, C. Rodriguez, R. Diaz, S. Martínez, One-Step Cell Lysis and DNA Concentration in a Multisection Insulator-Based Dielectrophoretic Device, submitted to the 14th AICHE Annual Meeting, Atlanta, GA, USA, 16-21 Nov, 2014. 52. V. Perez, V. Ho, S. Navarro, L. Kulinsky, M. Madou, S. Martínez, The impact of electrode geometry in Dielectrophoretic effect for multilayer PPyDEP-based devices, submitted to the 14th AICHE Annual Meeting, Atlanta, GA, USA, 16-21 Nov, 2014. 51. V. Perez, V. Ho, R. Celis, L. Kulinsky, M. Madou, S. Martínez, Improving dielectrophoretic manipulation efficiency employing pitted and bumpy interdigitated electrodes, submitted to the 14th AICHE Annual Meeting, Atlanta, GA, USA, 16-21 Nov, 2014. 50. V. Perez, V. Ho, L. Kulinsky, S. Martínez, Dielectrophoresis-assisted electroconductive polymerbased fabrication of high surface area electrodes, SPIE Smart Structures and Materials + Nondestructive Evaluation and Health Monitoring, San Diego, USA, 9 13 Mar 2014. Sergio O. Martínez 5

[2013] 49. V. Ho, V. Perez, L. Kulinsky, M. Madou, S. Martínez, Electropolymerization Based Micromanufacturing of Three-Dimensional High Surface Area Electrodes, 8th International Conference on MicroManufacturing, Victoria, Canada, 25 28 Mar 2013. 48. A. Rendón, S. Camacho, S. Martínez, Nondestructive Characterization of Residual Stress within CMOS-based Composite Microantilevers, SPIE Smart Structures and Materials + Nondestructive Evaluation and Health Monitoring, San Diego, USA, 10 14 Mar 2013. 47. A. Salazar, S. Camacho, O. Rossetto, S. Martínez, Electromagnetic Modeling of Surface Plasmon Resonance with Kretschmann Configuration for Biosensing Applications in a CMOS-compatible Interface, Proc. SPIE, Physics and Simulation of Optoelectronic Devices XXI, Bernd Witzigmann, Marek Osinski, Fritz Henneberger, Yasuhiko Arakawa, Eds, vol. 8619, San Francisco, USA, 2 7 Feb 2013. [2012] 46. A. Salazar, S. Camacho, O. Rossetto, S. Martínez, CMOS Active Column Sensor for Biodetection Applications based on Surface Plasmon Resonance, 19th IEEE International Conference on Electronics, Circuits, and Systems ICECS 2012, Seville, Spain, 9 12 Dec 2012. 45. V. Pérez, V. Ho, L. Kulinsky, B. Lapizco, S. Martinez, M. Madou, 3D Carbon Cages for Dielectrophoretic-based Bioparticle Separation/Concentration Applications, 12th AICHE Annual Meeting, Pittsburgh, PA, USA, 28 Oct -2 Nov, 2012. 44. V. Pérez, V. Ho, L. Kulinsky, B. Lapizco, M. Madou, S. Martinez, C-MEMS Based Electrodes for the Dielectric Characterization of Microparticles Employing Dielectrophoresis, 12th AICHE Annual Meeting, Pittsburgh, PA, USA, 28 Oct -2 Nov, 2012. 43. J. Rodríguez, C. Mendoza, G. Dieck, S. Martínez, Characterization of Interdigitated Electrode Structures for Water Contaminant Detection using a Hybrid Voltage Divider and a Vector Network Analyzer, 34th Annual International Conference of the IEEE Engineering in Medicine and Biology Society EMBC 2012, San Diego, USA, 28 Aug 1 Sep, 2012. 42. S. Camacho, P. Gilgunn, S. Martínez, G. Fedder, A high-speed, bimodal, CMOS-MEMS resonant scanner driven by temperature-gradient actuators, Proc. SPIE, MOEMS and Miniaturized Systems XI, Harald Schenk, Wibool Piyawattanametha, Wilfried Noell, Eds, vol. 8252, San Francisco, USA, 21-26 Jan, 2012. [2011] 41. J. Gómez, V. Pérez, H. Moncada, O. Rossetto, G. Dieck, S. Martínez, A Multi-channel Sinusoidal Generator for Electrokinetic Stimulation of Microfluidic Platforms, 8th IEEE Electronics, Robotics and Automotive Mechanics Conference CERMA 2010, Cuernavaca, México, 15-18 Nov, 2011. 40. M. Vázquez, J. Gómez, S. Camacho, G. Dieck, S. Martínez, Modeling of a CMOS Active Pixel Image Sensor: Towards Sensor Integration with Microfluidic Devices, 8th IEEE Electronics, Robotics and Automotive Mechanics Conference CERMA 2010, Cuernavaca, México, 15-18 Nov, 2011. Sergio O. Martínez 6

39. C. Mendoza, G. Dieck, S. Martínez, M. Madou, M. Videa, S. García, Carbon microelectrode arrays for multiplexed potentiostat performing electrochemical cyclic voltammetry, 9 Congreso Internacional sobre Innovación y Desarrollo Tecnológico, Cuernavaca, México, 23-25 Nov, 2011. 38. H. Moncada, V. Pérez, R. Martínez, S. Martínez, M. Madou, B. Lapizco, Dielectrophoretic assessment of microparticle dielectric properties employing a planar carbon electrode platform, 11th AICHE Annual Meeting, Minneapolis, MN, USA, 16-21 Oct, 2011. 37. M. López, A. Gerstlauer, A. Ávila, S. Martínez, A Programmable and Configurable Multi-port System-on-Chip for Stimulating Electrokinetically-driven Microfluidic Devices, 33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society EMBC11, pp. 8361-8364, Boston, USA, 30 Aug 3 Sep, 2011. 36. J. Gómez, H. Moncada, O. Rossetto, R. Martínez, B. Lapizco, M. Madou, S. Martínez, An Application Specific Multi-Channel Stimulator for Electrokinetically-Driven Microfluidic Devices, 9th IEEE Annual Northeast Workshop on Circuits and Systems NEWCAS11, pp. 350-353, Bordeaux, France, June 26-29, 2011. 35. H. Gutiérrez, S. Camacho, G. Dieck, S. Martínez, Design and Simulation of a Self-Assembled MEMS Force Sensor for Minimally Invasive Surgery, aceptado para publicación en 6th IEEE Sensors Applications Symposium SAS11, San Antonio, TX, USA, 22-24 Feb, 2011. [2010] 34. H. Moncada, V. Pérez, R. Martínez, S. Martínez, M. Madou, B. Lapizco, Dielectrophoretic Characterization of Microorganisms Employing Three Dimensional Carbon Electrodes, 10th AICHE Annual Meeting, Salt Lake City, USA, 7-12 Nov 2010. 33. A. Bautista, O. Rossetto, G. Dieck, S. Martínez, A 0.5V 94db SNR CT-Sigma-Delta Modulator for Implantable and Portable Biomedical Devices, 17th IEEE International Conference on Electronics, Circuits, and Systems ICECS 2010, pp. 555-558, Athens, Greece, 12 15 Dec 2010. 32. A. Martínez, G. Dieck, S. Martínez, Modeling and Simulation of Infrared Sensors Using Cantilever and Bridge Structures, 7th IEEE Electronics, Robotics and Automotive Mechanics Conference CERMA 2010, pp. 717-720, Cuernavaca, México, 28 Sep - 1 Oct, 2010. 31. A. Losoya, S. Camacho, S. Martínez, Design of a CMOS-MEMS Diffraction Grating for Near-Infrared Spectroscopy of Biomolecules, 7th IEEE Electronics, Robotics and Automotive Mechanics Conference CERMA 2010, pp. 737-740, Cuernavaca, México, 28 Sep - 1 Oct, 2010. 30. A. Méndez, S. Camacho, S. Martínez, Design Space Exploration of Z-Axis CMOS-MEMS Accelerometers, 7th IEEE Electronics, Robotics and Automotive Mechanics Conference CERMA 2010, pp. 745-748, Cuernavaca, México, 28 Sep - 1 Oct, 2010. 29. L. Cantú, I. Sánchez, L. Garza, S. Martínez, Feedforward Compensation of Exercise in Diabetes, Proceedings of the 18th Mediterranean Conference on Control and Automation, pp. 1335-1340, Marrakech, Morocco, 23-25 June, 2010. [2009] 28. J. Baylón, A. Chávez, S. Martínez, C. Reyes, B. Lapizco, Particle manipulation employing alternating current electric fields in an array of insulators, 9º AICHE Annual Meeting, Nashville, USA, 8-13 Nov 2009. Sergio O. Martínez 7

27. J. Baylón, A. Chávez, S. Martínez, C. Reyes, B. Lapizco, Insulator-based Dielectrophoresis with Direct Current Electric Fields, 9º AICHE Annual Meeting, Nashville, USA, 8-13 Nov 2009. [2008] 26. I. Martínez, B. Lapizco, H. Moncada, M. Rito, S. Martínez, Electrokinetic velocity characterization of microparticles in glass microchannels, 8º AICHE Annual Meeting, Philadelphia, USA, 16-21 Nov, 2008. 25. S. Ozuna, B. Lapizco, M. Rito, S. Martínez, C. Reyes, Performance Characterization of an Insulator- Based Dielectrophoretic Microdevice, 8º AICHE Annual Meeting, Philadelphia, USA, 16-21 Nov, 2008. 24. F. Heredia, C. Carbajal. S. Martínez, Direct Digital-Frequency Synthesizer for Dielectrophoresis, IEEE Electronics, Robotics and Automotive Mechanics Conference: CERMA 2008, Cuernavaca, México, pp. 570-574, 30 Sep 4 Oct, 2008. 23. O. Flotte, A. Pineda, G. Dieck, A. Ávila, S. Martínez, F. Bouchereau, On the performance of Active Noise Control (ANC) FX-LMS and FBFX-LMS algorithms using a DSP for Duct Network Noise Attenuation, IEEE Electronics, Robotics and Automotive Mechanics Conference: CERMA 2008, Cuernavaca, México, pp. 575-581, 30 Sep 4 Oct, 2008. 22. Z. Pineda, G. Dieck, S. Martínez, A. Ávila, A switching capacitor CMOS based device for hands-free Electrolarynx activation using Electromyographic signals, IEEE Electronics, Robotics and Automotive Mechanics Conference: CERMA 2008, Cuernavaca, México, pp. 8-13, 30 Sep 4 Oct, 2008. 21. R. Martínez, J. Andrade, E. Collado, S. Martínez, M. Madou, A high throughput multi-stage, multifrequency filter and separation device based on carbon dielectrophoresis, 11 th Annual Nanotechnology Conference and Trade Show: Nanotech 2008, Boston, USA, vol. 3, pp. 316-319, 1-5 Jun, 2008. 20. R. Martínez, E. Collado, S. Cito, S. Martínez, M. Madou, Fluido-Dynamic and electromagnetic characterization of 3D carbon dielectrophoresis with finite element analysis, 11 th Annual Nanotechnology Conference and Trade Show: Nanotech 2008, Boston, USA, vol. 3, pp. 265-268, 1-5 Jun, 2008. 19. I. Martínez, B. Lapizco, H. Moncada, M. Rito, S. Martínez, Determinación de movilidades electrocinéticas variando el medio de suspensión en microcanales para microfluídica, 29o. Encuentro Nacional de la AMIDIQ, Puerto Vallarta, México, 13-16 May, 2008. [2007] 18. A. Bautista, S. Martínez, G. Dieck, O. Rossetto, An ultra-low voltage high gain operational transconductance amplifier for biomedical applications, 1 st Design and Architectures for Signal and Image Processing Workshop, Grenoble, Francia, 27-29 Nov, 2007. 17. B. Lapizco, S. Ozuna, M. Rito, C. Reyes Betanzo, E. Collado, S. Martínez, Insulator based dielectrophoresis: effects of bulk medium properties, 5 th International Conference on Nanochannels, Microchannels and Minichannels, Puebla, México, 18-20 Jun, 2007. [2006] 16. A. Ávila, R. Santoyo, S. Martínez, Hardware/software implementation of the EEG signal compression module for an ambulatory monitoring subsystem, Sixth IEEE International Caribbean Conference on Devices, Circuits and Systems, Playa del Carmen, México, pp. 125-129, 26-28 Apr, 2006. Sergio O. Martínez 8

[2005] 15. S. Acha, D. Olguín, S. Martínez, Transmisión Inal{mbrica de Señales Electroencefalogr{ficas, Decimosexta Reunión de Otoño de Comunicaciones, Computación, Electrónica y Exposición Industrial, IEEE ROC&C 2005, Acapulco, México, 24 Nov 4 Dic, 2005. 14. I. Sánchez, R. Morales, S. Martínez, Glucose optimal control system in Diabetes treatment, 3rd Internacional Conference on Computer Methods for Science and Engineering, Loutraki, Greece, 21-26 Oct 2005, published as Lecture Series on Computer & Computational Sciences, Brill Academic Publishers, vol. 4, pp. 831-834, 2005. 13. S. Camacho, S. Martínez, Mode shape analysis of bimorph thermal actuators for parallel two-axis resonant scanning micromirrors, TEXMEMS VII, El Paso, USA, 21-22 Sep, 2005. 12. A. Ávila, R. Santoyo, S. Martínez, G. Dieck, Hardware/Software implementation of a discrete cosine transform DCT algorithm using System C, RECONFIG 2005, Puebla, México, pp. 180-183, Sep, 2005. 11. F. Cantú, S. Mora, J. Díaz, H. Ceballos, S. Martínez, D. Jiménez, A knowledge-based entrepreneurial approach for business intelligence in strategic technologies: Bio-MEMS, Americas Conference on Information Systems, AMCIS 2005, Omaha, Nebraska, USA, 11-15 Aug, 2005. 10. I. Sánchez, R. Morales, S. Martínez, Linear quadratic control model in biomedical engineering, 15th European Symposium on Computer Aided Process Engineering, ESCAPE 2005, Barcelona, Spain, pp. 1195-1200, 29 May 1 Jun, 2005. 9. D. Olguin, F. Bouchereau, S. Martínez, Adaptive notch filter for EEG signals based on the LMS algorithm with variable step-size parameter, 39th Conference on Information Sciences and Systems, CISS 2005, Johns Hopkins University, Baltimore, Maryland, 16-18 Mar, 2005. 8. I. Sánchez, R. Morales, S. Martínez, Comparison of servocontrol and regulatory approaches based on linear quadratic optimal control for continuous glucose control in diabetic patients, 24th IASTED International Conference on Modelling, Identification and Control, Innsbruck, Austria, pp. 372-377, Feb, 2005. [Before 2005] 7. G. Nicolescu, S. Martínez, L. Kriaa, W. Youssef, S. Yoo, B. Charlot, A. Jerraya, Application of multidomain and multi-language cosimulation to an optical MEM switch design, ASPDAC, Bangalore, India, 7-11 Jan, 2002. 6. S. P. Levitan, T. P. Kurzweg, J. A. Martinez, D. M. Chiarulli, L. Kriaa, W. Youssef, S. Martínez, G. Nicolescu, A. A. Jarraya, B. Courtois, A comparison of multi-domain modeling techniques for MEMS based optical cross connect switches, 39th DAC, New Orleans, USA, 10-14 Jun, 2002. 5. L. Kriaa, W. Youssef, G. Nicolescu, S. Martínez, S. Levitan, J. Martínez, T. Kurzweg, A. A. Jerraya, B. Courtois, SystemC-based cosimulation for global validation of MOEMS, Proc. SPIE, Design, Test, Integration, and Packaging of MEMS/MOEMS 2002, Bernard Courtois, Jean Michel Karam, Karen W. Markus, Bernd Michel, Tamal Mukherjee, James A. Walter, Eds, vol. 4755, pp. 64-70, 2002. 4. S. Martínez, B. Courtois, Insertion losses in micro-machined free-space optical cross-connects due to fiber misalignments, Proc. SPIE, Design, Test, Integration, and Packaging of MEMS/MOEMS 2001, Bernard Courtois, Jean Michel Karam, Steven P. Levitan, Karen W. Markus, Andrew A. Tay, James A. Walter, Eds, vol. 4408, pp. 289-300, 2001. Sergio O. Martínez 9

3. S. Martínez, B. Courtois, Study of scalability for micromachined free-space optical cross-connects, Proc. SPIE, Optoelectronic Integrated Circuits and Packaging V, James G. Grote, Randy A. Heyler, Eds, vol. 4290, pp. 105-115, 2001. 2. Z. Juneidi, K. Torki, S. Martínez, G. Nicolescu, A. Jerraya, B. Courtois, Global modeling and simulation of system-on-chip embedding MEMS devices, ASICON, Shanghai, China, pp. 666-669, 22-25 Oct, 2001. 1. F. Martínez, S. Martínez, C. Aguirre, G. Dieck, Surface laplacian mapping of brain evoked potentials: data gathering and processing using a DSP system and Matlab, Signal and Image Processing International Conference, Las Vegas, USA, 28-31 Oct, 1998. PUBLIC-AWARENESS-OF-SCIENCE PAPERS 2. S. Camacho, S. Martínez, Endoscopic biomedical imaging based on micro-opto-electro-mechanical scanners, Transferencia, no. 83, Jul 2008. 1. S. Martínez, I. Sánchez, Oportunidades de las tecnologías MEMS en medicina: avances en el estado de Nuevo León, Revista Conocimiento, Consejo de Ciencia y Tecnología del Estado de Nuevo León, vol. 4, pp. 14-15, 15-28 Abr, 2005. BOOK CHAPTERS 5. A. García, J. Díaz, S. Martínez, G. Dieck, MEMS, Las Megatendencias Tecnológicas actuales y su impacto en la identificación de oportunidades estratégicas de negocios, ITESM, Monterrey, México, 2009. 4. F. Cantú, S. Mora, J. Díaz, H. Ceballos, S. Martínez, D. Jiménez, A methodology for strategic intelligence: a roadmap model, a knowledge-based tool and a Bio-MEMS case, Strategic Intelligence: Concepts and Cases, Taylor & Francis, USA, 2006. 3. S. Martínez, J. Goy, Les MOEMS et les imageurs CMOS, in Dispositifs et Physique des Microsystèmes sur Silicium, Paris, Hermès Science Publications, 2002. 2. S. Mir, S. Martínez, Introduction aux microsystèmes sur silicium, in La Conception des Microsystèmes sur Silicium, Paris, Hermès Science Publications, 2002. 1. B. Charlot, S. Martínez, S. Mir La CAO des microsystèmes, in La Conception des Microsystèmes sur Silicium, Paris, Hermès Science Publications, 2002. ADVISED PHD THESIS 10. Melissa Marlene Rodríguez Delgado, Modeling and fabrication of a SPR-based biosensing platform for phenolic compounds, Ph.D. in Engineering Sciences, ITESM, Monterrey Campus, expected completion date: December 2014. Advisors: Roberto Parra y Sergio Martínez. In process. 9. Matías Vázquez Piñón, Modeling and implementation of AC electrosmotic micropumps based on high-aspect-ratio carbon electrodes, Ph.D. in Information Technology and Communications, ITESM, Monterrey Campus, expected completion date: December 2014. Advisor: Sergio Martínez. In process. 8. Adrián Daniel Losoya Leal, Design of a SPR-based competitive immunoassay for therapeutic drug monitoring of amikacin, Ph.D. in Information Technology and Communications, ITESM, Monterrey Sergio O. Martínez 10

Campus, expected completion date: December 2014. Advisors: Sergio Martínez, Laura Lechuga (Center for Nanoscience and Nanotechnology, Barcelona). In process. 7. Arnoldo Salazar Soto, Design and implementation of a CMOS imager with active column for SPRbased sensors, Ph.D. in Information Technology and Communications, ITESM, Monterrey Campus, December 2013. Advisor: Sergio Martínez, Olivier Rossetto (Université Joseph Fourier). 6. Víctor Hugo Pérez González, Dielectrophoresis-assisted electroactive-polymer-based microfabrication process for the development of multilayer and high surface area electrodes, Ph.D. in Information Technology and Communications, ITESM, Monterrey Campus, May 2013. Advisors: Sergio Martínez, Marc Madou (University of California, Irvine). 5. José Isabel Gómez Quiñones, Design and fabrication of an application specific multi-channel stimulator for electrokinetically-driven microfluidic devices, Double Degree: Ph.D. in Information Technology and Communications, ITESM, Monterrey Campus; PhD in Microelectronics and Microsystems, UJF, Grenoble, December 2011. Advisors: Sergio Martínez y Olivier Rossetto (Université Joseph Fourier). 4. Martha Salomé López de la Fuente, Definition, design and implementation of a processor-based stimulation system for electrokinetically-driven fluidic devices, Ph.D. in Information Technology and Communications, ITESM, Monterrey Campus, May 2011. Advisors: Sergio Martínez, Andreas Gertslauer (University of Texas at Austin). 3. Sergio Camacho León, Design, fabrication and characterzation of a high-speed bimodal CMOS- MEMS resonant scanner driven by temperature-gradient actuators, Ph.D. in Information Technology and Communications, ITESM, Monterrey Campus, May 2010. Advisors: Sergio Martínez, Gary Fedder (Carnegie Mellon University). 2. Alfredo Farid Bautista Delgado, Design of an ultra-low voltage analog front-end for an electroencephalography system, Double Degree: Doctorado en Tecnologías de Información y Comunicaciones, ITESM, Campus Monterrey; PhD in Microelectronics and Microsystems, UJF, Grenoble, June 2009. Advisors: Sergio Martínez y Olivier Rossetto (Université Joseph Fourier). 1. Irma Yolanda Sánchez Chávez, Evaluation of hydrogel materials for insuline delivery in closed loop treatment of Diabetes Mellitus, Ph.D. in Engineering Sciences, ITESM, Monterrey Campus, January 2008. Advisors: Sergio Martínez, Nicholas Peppas (University of Texas, Austin). ADVISED MASTER THESIS 32. Juan Felipe Yee de León, SERS based immunoassay for detection of tumor markers using 3D carbon structures, Master of Science in Electronic Engineering, ITESM, Monterrey Campus, expected completion date: December 2014. Advisors: Sergio Martínez, Víctor Pérez, In process. 31. Javier Alejandro Hernández Castro, Design and Implementation of Polydimethylsiloxane Devices for Contactless AC Electro-osmotic Micropumps, Master of Science in Electronic Engineering, ITESM, Monterrey Campus, May 2013. Advisor: Sergio Martínez. 30. Adrián Abdalá Rendón Hernández, A CMOS-based cantilever platform using adsorption-induced surface stress and piezoresistive transduction for biosensing, Master of Science in Electronic Engineering, ITESM, Monterrey Campus, December 2012. Advisor: Sergio Martínez. Sergio O. Martínez 11

29. Marco Antonio Parra Vilchis, Design and implementation of a configurable electrical stimulator for microfluific devices, Master of Science in Electronic Engineering, ITESM, Monterrey Campus, May 2012. Advisor: Sergio Martínez. 28. Matías Vásquez Piñón, Modeling of a CMOS active pixel image sensor: Towards sensor integration with microfluidic devices, Master of Science in Electronic Engineering, ITESM, Monterrey Campus, May 2011. Advisor: Sergio Martínez. 27. Alejandro Méndez Moreno, Design and implementation of a CMOS-compatible suspension system for an accelerometer, Master of Science in Electronic Engineering, ITESM, Monterrey Campus, December 2010. Advisor: Sergio Martínez. 26. Adrián Daniel Losoya Leal, Design of a CMOS-compatible microspectrophotometer for biomedical applications, Master of Science in Electronic Engineering, ITESM, Monterrey Campus, December 2010. Advisor: Sergio Martínez. 25. Eduardo Andrés Barredo Ochoa, Design and implementation of a CMOS interface for non-invasive optical biosensors, Master of Science in Electronic Engineering, ITESM, Monterrey Campus, December 2009. Advisor: Sergio Martínez. 24. Agustín Emmanuel Carvajal Rivera, Design and implementation of a glucose sensor based on Pulse Glucometry, Master of Science in Electronic Engineering, ITESM, Monterrey Campus, fecha estimada de terminación, December 2009. Advisor: Sergio Martínez. 23. Jorge Andrade Román, Programmable multichannel Sine Wave Generator for a C-MEMS based Dielectrophoretic Filter, Master of Science in Electronic Engineering, ITESM, Monterrey Campus, December 2008. Advisors: Sergio Martínez y Cuauhtémoc Carbajal (ITESM/CEM). 22. Carlos Alejandro Robles Rubio, Sequential detection of artifacts in electroencephalographic signals using nonparametric statistical methods, Master of Science in Electronic Engineering, ITESM, Monterrey Campus, November 2008. Advisors: Frantz Bouchereau y Sergio Martínez. 21. José Israel Martínez López, Medición de los efectos del medio de suspensión en microdispositivos para electrocinética, Master of Science in Biotechnology, ITESM, Monterrey Campus, July 2008. Advisors: Blanca Lapizco y Sergio Martínez. 20. Esther Collado Arredondo, Modelling and simulation of an insulator-based DEP microdevice, Master of Science in Electronic Engineering, ITESM, Monterrey Campus, November 2007. Advisors: Sergio Martínez y Blanca Lapizco. 19. Carlos José Díaz Torres, Diseño de un amplificador operacional CMOS para la adquisición de señales de EEG, Master of Science in Electronic Engineering, ITESM, Monterrey Campus, August 2007. Advisor: Sergio Martínez. 18. José Alberto Quiroga Contreras, Experimental research of the polyamidoamine dendrimer as a coating layer for microfabricated silicon biosensors, Master of Science in Electronic Engineering, ITESM, Monterrey Campus, August 2007. Advisor: Sergio Martínez. 17. Sergio Camacho León, Diseño de microespejo CMOS de barrido resonante para sistemas endoscópicos de tomografía óptica, Master of Science in Electronic Engineering, ITESM, Monterrey Campus, May 2006. Advisor: Sergio Martínez. 16. Daniel Olguín Olguín, Adaptive digital filtering algorithms for the elimination of power line interference in electroencephalographic signals, Master of Science in Electronic Engineering, ITESM, Monterrey Campus, May 2005. Advisors: Sergio Martínez y Frantz Bouchereau. Sergio O. Martínez 12

15. Alfredo Farid Bautista Delgado, Diseño de un sistema de monitoreo y procesamiento de sonidos cardiacos para su aplicación en un sistema de medición contínua y no invasiva de la presión arterial, Master of Science in Electronic Engineering, ITESM, Monterrey Campus, July 2005. Advisors: Sergio Martínez y José González. 14. Eduardo Francisco Torres Puente, Fuente de poder de corriente alterna monof{sica de estado sólido para la generación de distorsión armónica. Master of Science in Energetic Engineering, ITESM, Monterrey Campus, December 2003. Advisors: Sergio Martínez y Javier Rodríguez. 13. Francisco Martínez Santiestéban, Mapeo del laplaciano superficial aplicado a los potenciales evocados del cerebro humano, Master of Science in Electronic Engineering, ITESM, Monterrey Campus, May 1998. Advisors: Graciano Dieck y Sergio Martínez. 12. Javier Aguilera Urbina, Sistema modular para el monitoreo de potencia y par{metros eléctricos, Master of Science in Electronic Engineering, ITESM, Monterrey Campus, September 1997. Advisor: Sergio Martínez. 11. Mauro Alvarado, Aplicaciones de un sistema de monitoreo de par{metros eléctricos, Master of Science in Electronic Engineering, ITESM, Monterrey Campus, December 1997. Advisor: Sergio Martínez. 10. Hugo Amezcua, Desarrollo de funciones para la integración de herramientas de Spitec, Master of Science in Electronic Engineering, ITESM, Monterrey Campus, July 1996. Advisor: Sergio Martínez. 9. Jorge Borbolla Romero, Sistema Port{til de Medición de Armónicas en Sistemas de Potencia, Master of Science in Electronic Engineering, ITESM, Monterrey Campus, May 1996. Advisor: Sergio Martínez. 8. Raúl Dávalos Hernández, SIGS-Sistema Interactivo de Graficación para Spice, Master of Science in Electronic Engineering, ITESM, Monterrey Campus, May 1996. Advisor: Sergio Martínez. 7. Sergio Dumit Malacón Gámez, Fuentes de Poder de Regulación por Conmutaciones, Master of Science in Electronic Engineering, ITESM, Monterrey Campus, December 1995. Advisor: Sergio Martínez. 6. Félix Rafael Alcolea González, Desarrollo de las Funciones de An{lisis, Graficación e Impresión para un Postprocesador Interactivo de Spice3, Master of Science in Electronic Engineering, ITESM, Monterrey Campus, August 1995. Advisor: Sergio Martínez. 5. Héctor Hugo López Rizo, Generación autom{tica de modelos de diodos para Spice3, Master of Science in Electronic Engineering, ITESM, Monterrey Campus, May 1995. Advisor: Sergio Martínez. 4. Joaquín Guillén Rodríguez, Desarrollo de una interfase gr{fica interactiva para Spice3, Master of Science in Electronic Engineering, ITESM, Monterrey Campus, May 1994. Advisor: Sergio Martínez. 3. Raúl Crespo Saucedo, Sistema de control de una casa inteligente, Master of Science in Electronic Engineering, ITESM, Monterrey Campus, May 1994. Advisor: Sergio Martínez. 2. Manuel Ramón Rodríguez Ábrego, Descripción y Medición de los Par{metros de Diodos y Transistores Bipolares para su Modelación en Pspice, Master of Science in Electronic Engineering, ITESM, Monterrey Campus, December 1992. Advisor: Sergio Martínez. 1. Jorge A. de la Rosa H. Luz, Implementación de un Sistema de Adquisición de Datos para el Laboratorio de Ingeniería Química, Master of Science in Electronic Engineering, ITESM, Monterrey Campus, May 1988. Advisor: Sergio Martínez. Sergio O. Martínez 13

PATENTS 1. M. Lemiszka, M. Reyes, G. Dieck, S. Martínez, Cojín microcontrolado y método de control para la prevención de úlceras. Patent Application Number: NL/a/2006/000002. Filed on January 11, 2006. Published on Jul, 2007. Patent Granted on October 22, 2010. FUNDRAISING Research Projects Sponsored by Conacyt Modeling, Design, Fabrication and Characterization of AC Electrosmotic Micropumps with High- Aspect-Ratio Electrodes, Principal Investigators: Marc Madou/UC-Irvine; V. Pérez & Sergio Martínez /ITESM. Sponsor: UC-Mexus/CONACYT. Allocated Budget: US$ 25,000. Project Period: 01 Jul 2014 31 Dec 2015. Fabrication and Characterization of Carbon Micro/Nanostructures and their Application in Microfluidic Devices and Sensors, Principal Investigator: Sergio Martínez, Sponsor: CONACYT Estancias Sabáticas en el Extranjero para la Consolidación de Grupos de Investigación, Allocated Budget: US$ 12,000. Project Period: 01 Aug 2014 31 Jul 2015. On the potential of carbon-electrode dielectrophoresis for bioparticle characterization, Principal Investigators: Marc Madou/UC-Irvine; Sergio Martínez & Blanca Lapizco/ITESM. Sponsor: UC- Mexus/CONACYT. Allocated Budget: US$ 25,000. Project Period: 01 Aug 2009 31 Mar 2012. Multiplexed potentiostat for activation of individually addressable microelectrode arrays, Principal Investigators: Graciano Dieck/ITESM, La Rue/UC-Irvine, Associated Researchers: Sergio Martínez, Marc Madou. Sponsor: UC-Mexus/CONACYT. Allocated Budget: US$ 25,000. Project Period: Oct 2007 Mar 2009. 3D Dielectrophoresis with C-MEMS: design, simulation & implementation, Principal Investigators: Sergio Martínez, Marc Madou/UC-Irvine. Sponsor: UC-Mexus/CONACYT, Allocated Budget: US$ 24,000. Project Period: Oct 2006 Sep 2009. Design of an electronic intra-medullar, wireless device for the detection of leukemia relapse after chemotherapy treatment, Principal Investigator: Sergio Martínez. Sponsor: Fondo Sectorial de Salud/CONACYT, ITESM. Allocated Budget: MX$1,750,000 (Conacyt), MX$470,000 (ITESM). Project Number: Salud-2004-01-006. Project Period: 2005-2009. Design, fabrication and application of silicon-based wireless microelectrodes compatible with Microelectronics for biopotential recording in basic and clinic medicine, Principal Investigator: Sergio Martínez. Sponsor: Conacyt. Allocated Budget: MX$ 533,000. Proyect Period: 2003. Other Sponsored Projects Seed funds for the Biointeractive and BioMEMS Research Group, Principal Investigator: Sergio Martínez. Sponsor: ITESM. Allocated Annual Budget: MX$1,500,000. Project Period: from Jan 2005 to Jun 2014. Feedback Control Systems for Insulin Delivery in Patients with Diabetes Mellitus. Principal Investigators: Sergio Martínez, Nicholas Peppas/UTA. Sponsors: UTA, Schlumberger. Allocated Budget: US$10,000 (UTA), US$30,000 (Schlumberger). Project Period: Aug 2006 Jul 2007. Sergio O. Martínez 14

Microelectronics and Microsystems Design Laboratory. Sponsors: SUN Microsystems, ITESM. Sergio O. Martínez 15