PROGRAMME NORDIC CONGRESS IN CLINICAL BIOCHEMISTRY. TUESDAY JUNE 14 th 2016



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May 25, 2016 PROGRAMME NORDIC CONGRESS IN CLINICAL BIOCHEMISTRY 2016 BASIC AND TRANSLATIONAL RESEARCH LAB ORGANISATION DISEASE ENTITIES BREAKS & SOCIAL EVENTS TUESDAY JUNE 14 th 2016 14.00 16.00 Registration HCA 16.00-16.15 Opening ceremony 16.15-17.00 Plenary Session A Chairman: Rasmussen LM, Odense The Aging Society: Are we doing well? Are we doing good? Christensen K, Odense 17.00 19.00 Welcome Reception Møntergården NORDIC CONGRESS IN CLINICAL BIOCHEMISTRY 1

WEDNESDAY JUNE 15 th 2016 May 25, 2016 09.00-09.45 Plenary session B Chairman: Brandslund I, Vejle and Bojesen S, Copenhagen Big Data, Brunak S, Copenhagen 09.45-10.30 Coffee, Exhibition and Posters 10.30-12.30 Session 1 Big Data Chairmen: Bojesen S, Copenhagen and Brandslund I, Vejle Mining the Genome in Diabetes Hansen T, Copenhagen Kl. 11.00 11.30 Mining the Metabolomic Profile with Kenkodo Worseck J, Hannover Kl. 11.30 12.00 Mining Soft Data for Infection and Hospital Epidemics Møller JK, Vejle Kl. 12.00 12.30 Programs Algorithms and other software for Big Data Analysis and Presentation Holm F, Skanderborg Session 2 Pro Musica, HCA Preanalytics Chairmen: Kjell Grankvist, Sweden and Mads Nybo, Odense The role of EFLM WG-PRE in improving the quality of preanalytical phase in Europe Simundic A-M, Zagreb Kl. 11.00 11.15 Nordic Working Group on Preanalytics who, what and why? Nybo M, Odense Kl. 11.15 11.30 Nordic laboratories handle hemolyzed samples differently - Results from the Nordic hemolysis interference study Gidske G, Bergen Kl. 11.30 11.45 Use of questionnaires to follow venous blood specimen collection practices Grankvist K, Umeå Session 3 Møntergården, Møntergården 1 Bones in Cancer and Diabetes Chairmen: Jørgensen N, Glostrup and Jørgensen H, Copenhagen Kl. 10.30 11.15 Tumor-induced Osteomalacia Gafni R, Bethesda Kl. 11.15 12.00 The bone cancer partnership Delaissé JM, Vejle Kl. 12.00 12.30 Bone Disease and Diabetes Linde JS, Aalborg Kl. 11.45 12.00 Compliance of venous blood sampling procedures with the CLSI H3-A6 guideline in Norway: an observation study conducted in three Norwegian hospitals Kristensen G, Bergen Kl. 12.00 12.15 Blood sampling QC the experience so far Seemann TL, Odense NORDIC CONGRESS IN CLINICAL BIOCHEMISTRY 2

May 25, 2016 12.30-14.00 Lunch HCA 13.00-13.45 Company lectures Company lecture 1 by Roche Personalised Healthcare (PHC) and Companion Diagnostics (CDx) in Roche Perspective Narvestad JB, Concert Hall, HCA Company lecture 2 by Abbott High-sensitivity cardiac troponin I assay: Improving precision and patient care, Chapman AR, University of Edinburgh Møntergården 14.00-14.45 Plenary session C Chairman: Brasen, CL, Vejle and Rasmussen, LM, Odense Vitamin K-dependent matrix Gla-protein: a crucial switch to control ectopic mineralization Schurgers LJ, Maastricht 14.45-15.30 Coffee, Exhibition and Posters 15.30-17.00 Session 4 Astrup Prize Competition Chairmen: Rasmussen LM, Odense and the Astrup Committee Blood hsa-mir-122-5p and hsamir-885-5p levels associate with fatty liver and related lipoprotein metabolism - The Young Finns Study. Emma Raitoharju, Tampere, Finland Kl. 16.00 16.30 Cerebrospinal fluid neurogranin: relation to cognition and neurodegeneration in Alzheimer s disease. Erik Portelius, Göteborg, Sweden Kl. 16.30 17.00 A rare splice donor mutation in HP associates with higher nonhigh density lipoprotein cholesterol Hannes Helgason, Reykjavik, Iceland Session 5 Pro Musica, HCA Future biochemistry Chairmen: Bliksrud YT, Oslo and Brasen CL, Vejle Rapid Stratification of cancer patients using imaging and invivo mass spectrometric methods Zoltan T, London Kl. 16.00 16.30 Point of Care Test (POCT) in the prehospital setting in acute medicine Stengaard C, Aarhus Kl. 16.30 17.00 Automatic interhospital sample transportation Nybo J, Aalborg Session 6 Møntergården, Møntergården 1 Cancer Chairmen: Sørensen BS, Aarhus and Brandslund I, Vejle kl. 15.30-16.20 mrna analysis in cancer a word of warning Bustin S, Anglia Ruskin University, England Kl. 16.20 16.40 Targeted treatment in multiple myeloma Plesner T, Vejle Kl. 16.40 17.00 Monitoring effect of cancer treatment by plasma DNA analysis Spindler KLG, Aarhus 17.00-18.45 Beertasting, Wine, Mingle and Poster presentation HCA The bar is open and the first drink is FREE in the poster area, where poster presenters will discuss their poster NORDIC CONGRESS IN CLINICAL BIOCHEMISTRY 3

18.30 - Dinner and River Cruise / Dinner on your own / Company events 1. Dinner and river cruise on the river, Odense Å limited participation 300 persons - early registration recommended 2. Company Events - by invitation only 3. Dinner on your own (see map for possible recommended restaurants) May 25, 2016 NORDIC CONGRESS IN CLINICAL BIOCHEMISTRY 4

THURSDAY JUNE 16 th 2016 May 25, 2016 09.00-09.45 Plenary session D Chairman: NN, Finland and Brandslund I, Vejle Personalised Medicine and Precision Medicine The Concept of Precision Medicine Cancer and Beyond. Ford JM, Stanford University School of Medicine, San Francisco 09.45-10.30 Coffee, Exhibition and Posters 10.30-12.30 Session 7 Eldjarn Prize Competition Chairmen: Berg JP, Oslo and the Eldjarn Prize Committee Kl. 10.30 11.10 Cystatin C, a marker for successful aging and glomerular filtration rate, is not influenced by inflammation. Grubb A, Malmö Kl. 11.10 11.50 Diurnal variation of hematology parameters in healthy young males: The Bispebjerg study of diurnal variations. Sennels HP, Copenhagen Kl. 11.50 12.30 Identification of novel psychoactive drug use in Sweden based on laboratory analysis - initial experiences from the STRIDA project. Helander A, Stockholm Session 8 Frimurerlogen, Albanigade 16 Collaboration in Clinical Biochemistry: Nordic and international Chairmen: Sandberg S, Bergen and Hilsted L, Copenhagen Kl. 10.30 11.10 How can the African Federation of Clinical Chemistry cooperate with the Nordic and European countries Erasmus R, Cape Town Kl. 11.10 11.50 Cooperation between Nordic countries and between Nordic countries and the rest of the world Bliksrud YT, Oslo Kl. 11.50 12.30 Nordic laboratory specialists should engage in professional work in Europe Sandberg S, Bergen Session 9 Møntergården, Møntergården 1 Dementia and Biochemistry Chairmen: Heegaard NH, Copenhagen/Odense and Madsen JS, Vejle Alzheimer s Disease Teunissen C, Amsterdam Kl. 11.00 11.30 Rapid identification of a plateletderived alzheimer's disease-specific phenotype by biochip array technology Zellner M, Vienna Kl. 11.30 12.00 Validation of different assays for quantification of human αsynuclein Kruse N, Göttingen Kl. 12.00 12.30 New developments in Mass Spectrometry and high sensitivity immuneoassays for the differential diagnosis of dementia Höglund K, Gothenburg 12.30-14.00 Lunch HCA 13.00 13.45 Company lectures Company Lecture 3 by Siemens Company Lecture 4 by Thermo Fisher Scientific NORDIC CONGRESS IN CLINICAL BIOCHEMISTRY 5

May 25, 2016 Finding the needle in the fat haystack New European guidelines for Non-Alcoholic Fatty Liver Disease (NAFLD) Simonsson P, Siemens Healthineers Treatment of childhood obesity Including fatty liver disease Holm JC, Holbæk University Hospital Concert Hall, HCA Acute heart failure room for improvement using Mr-proANP and Procalcitonin (PCT) Schou M, Herlev Hospital Use of Turboflow LC-MS/MS in a clinical set-up Fruekilde PBN, Odense Møntergården 14.00-14.45 Plenary session E - HCA Chairman: Heegaard NH, Copenhagen/Odense and Kristensen, SR, Aalborg Exosomes and cancer diagnostics Kalluri R, Texas 14.45-15.30 Coffee, Exhibition and Posters 15.30-17.00 Session 10 Extracellular Vesicles and Micro particles Chairmen: Kristensen SR, Aalborg and Heegaard NH, Copenhagen/ Odense Extracellular vesicles: Blood, Sweat and Tears Böing AN, Amsterdam Kl. 16.00 16.15 Coagulation, microvesicles and venous thrombosis Kristensen SR, Aalborg Kl. 16.15 16.30 Luposomes: extracellular vesicles circulating in systemic lupus erythematosus Heegaard NH, Copenhagen/ Odense Kl. 16.30 17.00 Bioinspired exosome Mimetic Nanovesicles and exosomes for targeted delivery of chemotherapeutics Jang SC, Götheborg Session 11 Frimurerlogen, Albanigade16 Old tests with new applications Chairmen: Venge P, Uppsala and Wang P, Vejle Measurement of Cholecystokinin in Plasma Rehfeld JF, Copenhagen Kl. 16.00 16.30 Does lower than expected circulating natriuretic peptides concentrations play a role in obesity-related hypertension? Jeppesen JL, Copenhagen Kl. 16.30 17.00 Heart failure biomarkers Gøtze JP, Copenhagen Session 12 Møntergården, Møntergården 1 Coagulation Chairmen: Halfdan Larsen O, Aarhus, and Jespersen J, Esbjerg Laboratory testing in von Willebrand disease and standardization of von Willebrand analysis Budde U, Hamburg Kl. 16.00 16.20 Clinical aspects of von Willebrand syndrome: diagnosis, sub classification and treatment. Funding E, Copenhagen Kl. 16.20 16.40 Guidelines for lupus anticoagulant testing Sidelmann J, Esbjerg Kl. 16.40 17.00 Immunothrombosis: Interplay between coagulation and the inflammation system Palarasah Y, Esbjerg NORDIC CONGRESS IN CLINICAL BIOCHEMISTRY 6

May 25, 2016 17.15-18.15 Wine, Mingle and Poster presentation HCA The bar is open and the first drink is FREE in the poster area, where poster presenters will discuss their poster 19.00 - Congress Dinner - Danish Railway Museum (Danmarks Jernbanemuseum) http://www.jernbanemuseet.dk) Formal Congress Dinner at the Danish Railway Museum Awards - formal speeches - future organiser of the next Nordic congress on Clinical Chemistry in Helsinki, Finland - Dinner and dance NORDIC CONGRESS IN CLINICAL BIOCHEMISTRY 7

FRIDAY JUNE 17 th 2016 May 25, 2016 09.00-09.45 Plenary session F Chairman: Rasmussen LM, Odense and Beck-Nielsen H, Odense Incretins: Biochemistry and Clinical Relations Holst JJ, Copenhagen 09.45-10.30 Coffee, Exhibition and Posters 10.30-12.00 Session 13 Clinical Proteomics Chairmen: Madsen JS, Vejle and Overgaard M, Odense Post-translational modifications in biomarker discovery Larsen MR, Odense Kl. 11.00 11.30 Quantitative proteomics of tissue specific proteins in blood plasma Malmström J, Lund Kl. 11.30 12.00 Towards Targeted proteomics in clinical laboratories Overgaard M, Odense Session 14 Frimurerlogen, Albanigade16 Rational diagnostics Chairman: Hagve TA, (Norway) and Sheikh SP, Odense Kl. 10.30 11.15 Overtesting, Undertesting, Correct Testing, Rational Testing : The Slovak Experience Kovac G, Bratislava Kl. 11.15 11.35 Evidence-based Rational Diagnostics Sheikh SP, Odense Kl. 11.35 12.00 Utilization of Tests from a Hospital Director s point of view Brixen K, Odense Session 15 Møntergården DM: Individualised approach Chairmen: Beck-Nielsen H Rasmussen LM, Odense Individualised Treatment in Type 2 Diabetes Beck-Nielsen H, Odense Kl. 11.00 11.30 Towards precision medicine in diabetes Groop L, Malmö Kl. 11.30 12.00 Obesity and brain insulin resistance - cause or consequence Hâring HU, Tübingen 12.00-12.30 Closing Ceremony Goodbye Ivan Brandslund and Lars Melholt Rasmussen Welcome to the Nordic Congress on Clinical Chemistry 2018 in Helsinki, Finland by chairman of the organizing committee Solveig Linko 12.30-14.00 Lunch HCA 14.00 15.30 DSKB, Dansk Selskab for Klinisk Biokemi: Annual General Assembly, Room K4, HCA NORDIC CONGRESS IN CLINICAL BIOCHEMISTRY 8