DEPARTMENT OF CLINICAL PATHOLOGY DEGREE: Doctorate CLINICAL PATHOLOGY (CPMD) Programme Specification Date: 27/3/2012. A-Basic Information



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Zagazig University Faculty of Medicine جامعة الزقازيق كلية الطب البشرى DEPARTMENT OF CLINICAL PATHOLOGY DEGREE: Doctorate CLINICAL PATHOLOGY (CPMD) Programme Specification Date: 27/3/2012 A-Basic Information 1- Programme Title: Doctorate (MD) in Clinical Pathology.. 2- Final Award: MD degree in Clinical Pathology. 3-Programme type: Single Double Multiple 4-Responsible Departments: 1-Public Health department. 2-Clinical pathology department. 5- Programme duration: 3 academic years. 6-Number progamme courses:6 courses. Pre-requisite courses in: Statistic and methodology for MD students (MS), Computer and internet application in medicine (CA), compulsory courses in: Molecular biology(cpmd 01) and Immunology course(cpmd 02)and one of the elective courses in : Microbiology course(cpmd 03), Clinical chemistry(cpmd 04), Hematology (CPMD 05) and thesis(mdth). 7-Coordinator: Prof. Dr / Lamiaa Abdel Wahab. 8-External evaluators: Ekbal Abo Hashem, Faculty of Medicine, Mansoura University. 9-Last date of programme specifications approval: 10- Programme management team: 1

Prof/Naglaa Ali Khaifa Assist. Prof. Dr. Hananeesa Assist Prof/Dr. AminaM.Talaat Dr. Hoda A. Hagrass B-Professional Information: 1-Programme aims: The aim of this programme is to build the competencies of the candidate to point out applied microbiological, chemical, hematological and immunological laboratory investigations and their significance, interpret laboratory results scientifically, and the candidate will have a wide vision about the molecular biology and its important role.they should also be able to conduct cost- effective test. In addition, the candidate will have a wide vision about development of new methods and tools to analyze and criticize any research scientifically, and to use different technological methods which add to his/her Professional applications. 2- Intended Learning Outcomes (ILOs): By the end of the MD programme in Clinical pathology the candidate will be able to: A- Knowledge and Understanding KU1. Enumerate the medically significant pathogenic organisms (bacteria, viruses and fungi) and normal body flora in different body sites KU2. Discuss how to perform the best laboratory health care according to the available resources. KU3. State different automations in laboratory and its applications KU4. Identify bacterial causes of water contamination. 2

KU5.Discuss mechanisms of molecular genetics. KU6.Able to reach final diagnosis. KU7.Describe Cellular and humoral immunity and diseases of immunity clinical serology and immunology KU8. Describe the basics of serological and molecular techniques KU9.Recognize immunological basis of tumor immunology, transplantation, autoimmunity, immunodeficiency and hypersensitivity. KU10.Outline measures of infection control. KU11. Description Structure and function of normal blood cells with changes seen in benign and malignant diseases and acquired and hereditary disorders. KU12. Understand mechanisms of advances in hemostasis, fibrinolysis and hemostatic control B: Intellectual Skills IS1.Evaluate updated techniques in lab IS2.Follow Creative thinking. IS3.Evaluate cases and make proper diagnosis in different diseases IS4. Write scientific papers. IS.5. Assess the effectiveness of individual tests, strategies and protocols for the investigation of a disease(e.g Diabetes,disorders of lipoprotein metabolism). IS.6.Integrate the common and recent aspects of clinical hematology, anemia, Immune hematology, coagulation and oncology. IS.7.Integrate patients data and basic knowledge to select appropriate laboratory tests that help in diagnosis and management. IS.8. Successfully implement the chosen research methodology. IS9. Deal with different immunological disorders: rheumatic,git, endocrine etc.. 3

C- Professional/practical skills PS1. Recognize and respond appropriately to medical situations that are immediately life threatening and saving. PS2.Demonstrate problems encountered in different diagnostic techniques and how to overcome. PS3.Perform update tests of hemostasis, fibrinolysis and hemostatic control and blood banking. PS.4. Apply advanced molecular techniques PS.5. Perform different laboratory tests for evaluation of the immune system. PS6.Apply quality assurance and EQAS. PS7. Perform different laboratory techniques in clinical bacteriology, Immunology, chemistry and hematology. PS8. Perform coagulation tests and interpret different coagulation problem.. PS9. Evaluate karyotyping reports PS10.Develop a plan to integrate the results to reach diagnosis and interpret them. D- General &Transferable skills GS1.Analyze and use numerical data including simple statistical methods. GS2.Solve problems related to patient cope with changes in environment. GS3. Use information and communication technology effectively. GS4. Be discipline. GS5. Use different resources to gain knowledge and information. GS6. Develop rules and indicators to evaluate the performance of others. GS7. Work in a team and lead teams in different professional situation. 4

GS8. Be prepared for lifelong learning. GS9. Manage seminars in addition to the effective time management. GS10. Communicate well with patients & their families with honor & respect. 3. Academic standards: 3a. Generic standards of postgraduate programmes prepared by National Authority of Quality Assurance and Accreditation of Education (NAQAAE). المعاييرالقياسية العامة لبرامج الدراسات العليا التي أعدتها الهيئة القومية لضمان جودة التعليم واالعتماد ( 2009 )فبراير 3b. External reference (Benchmarks) (attached): Clinial Pathology Programme of Michigan State University 3c. Matrices: 1- Comparison between the intended learning outcomes (ILOs) of the Faculty of Medicine Zagazig university MD in Clinical Pathology programme and that of the Generic Academic standards of postgraduate programme prepared by National Authority of Quality Assurance and Accreditation of Education. Generic Academic standards of MD الدكتوراة ) programme المعايير العامة لبرامج الدراسات العليا)برامج 1 -المعرفة و الفهم: أ- النظريات و األساسيات والحديث من المعارف فى مجال التخصص وكذا في المجاالت ذات العالقة ب- المبادئ األخالقية و القانونية للممارسة المهنية في مجال التخصص. ت- مبادئ و أساسيات الجودة في الممارسات المهنية في مجال التخصص. ث- أساسيات و أخالقيات البحث العلمي وأدواته المختلفة ج- المعارف المتعلقة بآثار ممارسته المهنية على البيئة وطرق تنمية البيئة وصيانتها Comparable ILOs in the MD in Clinical Pathologyprogramme KU1 to KU12 Remarks % is fulfilled 5

المهارات الذهنية: أ- تحليل و تقييم المعلومات في مجال التخصص والقياس عليها واإلستنباط منها. ب- حل المشاكل المتخصصة استنادا على المعطيات المتاحة ت- الربط بين المعارف المختلفة لحل المشاكل المهنية. ث- اجراء دراسة بحثية تضف إلى المعارف. ج- تقييم المخاطر في الممارسات المهنية في مجال التخصص. ح- التخطيط لتطوير األداء في مجال التخصص. خ- أتخاذ القرارات المهنية في سياقات مهنية متنوعة. د- صياغة أوراق علمية ذ- اإلبتكار واإلبداع. ر- الحوار والنقاش المبنى على البراهين واألدلة. المهارات المهنية: أ -اتقان المهارات المهنية األساسية و الحديثة في مجال التخصص. ب -كتابة و تقييم التقارير المهنية. ت -تقييموتطوير الطرق واألدوات القائمة في مجال التخصص ج-إستخدام الوسائل التكنولوجية بما يخدم الممارسة المهنية. ح- التخطيط لتطور الممارسة المهنية وتنمية آداء اآلخرين. المهارات العامة و المتنقلة: أ -التواصل الفعال بأنواعه المختلفة ب -استخدام تكنولوجيا المعلومات بما يخدم الممارسة المهنية. ت -التقييم الذاتي والمستمر ث -استخدام المصادر المختلفة للحصول علي المعلومات والمعارف. ج -تعلييم اآلخرين وتقييم آداءهم. ح -العمل في فريق و قيادة فرق في سياقات مهنية مختلفة. خ -إدارة اللقاءات العلمية والوقت بكفاءة. د -التعلم الذاتي و المستمر. IS1- IS10 PS1 to PS10 GS1 to GS10 % is fulfilled % is fulfilled % is fulfilled 6

1 2 3 4 2. Comparison between the ILOs of the MD programme in Clinial Pathology, Faculty of Medicine- Zagazig University and Programme of Michigan State University. Clinical Pathology Programme of Michigan State University. Application and integration of technical skills in clinical chemistry. Biochemical basis of selected pathologic conditions including inborn errors of metabolism, endocrine and other genetic disorders. Emphasis on current diagnostic techniques. Application advanced hematology and hemostasis and Integration of cognitive material with clinical laboratory test results. Selected topics in hematology including pathogenesis, mechanisms and morphological pictures. Emphasis on laboratory tests and interpretation of results. Application and integration of theory and technical skills in immunology and immunohematology. Application and integration of theory and technical skills in clinical microbiology and ILOs in MD of Medical Microbiology programme, Faculty of Medicine, University. 7 Zagazig KU2,KU3,KU6,KU8 IS1,IS2,IS3,IS5IS7,IS8 PS2,PS4,Ps6,PS7,PS10 KU11,KU12 IS1,IS2,IS3,IS6,IS7 PS3,PS4,PS7,PS8,PS10 KU7,KU9 IS2,IS3,IS7,IS9 PS4,PS5,PS7,PS10 KU2,KU4,KU6 IS1,IS2,IS3,IS7 Clinical Pathology Approximate achievable ILOs 70% is fulfilled 70% is fulfilled 80% 70% is fulfilled

infectious disease PS1,PS2,PS4,PS7,PS10 5 MD s Thesis Research in KU6, KU8 % which there is simple methods of searching within simple item in clinical pathology to catch the ability of preparing a scientific paper. IS2, IS4 PS7 GS3, GS5, GS9. Thesis in a new area of Medical clinical pathology within the scientific research plan of the Department and Faculty 2- Programme structure: Course Units Teaching hours Weeks part Computer (CA) 11 48 24 1 st part Statistics (MS) 9 24 12 1 st Part Molecular Biology (CPMD 11 51 20 1 st part 01) Immunology (CPMD 02) 18 156 72 2 nd part Microbiology CPMD 03 12 115 47 2 nd part Clinical Chemistry CPMD 6 160 50 2 nd part 04 Haematology CPMD 05 4 240 72 2 nd part Thesis (MDTH) - 216 36 3 rd part (supervision) Total 71 919 297 8

Statistics (MS) Computer (CA) 4. Programme courses: Code No. Units Title No of Hours No of Theoretical & seminars Practical Total weeks 1 How to locate the proper source for 3 1 4 2 health and medical information. 2 How to decode URLs and identify 2 1 3 2 file types. 3 How to formulate effective search 3 2 5 2 statements. 4 How to evaluate the internet 3 2 5 2 information. 5 Citing internet documents and 3 2 5 2 avoiding plagiarism. 6 Web 2.0 and social / collaborative 3 2 5 2 internet tools. 7 Using of internet tools in evidence 3 2 5 4 based medicine. 8 Health on the net code of ethics. 2 2 2 9 Using of free online journal 2 2 4 2 databases. 10 Scope, uses, application of 3 2 5 2 Pubmedmedline database. 11 Medical Wiki, Blogs, groups, 3 2 5 2 multimedia and Health 2.0 tools. 1 Introduction to medical statistics. 2 1 1 2 2 Types of research methodology. 4 2 2 1 3 Population sampling. 2 1 1 1 4 Types of data presentation. 4 2 2 1 5 Summarization of data. 4 2 2 1 6 Normal distribution curve. 1 1 1 7 Tests of significance. 4 2 2 2 8 Types of errors, bias. 1 1 1 9 Correlation. 2 1 1 1 Total 54 29 83 36 9

CPMD 03 CPMD 02 CPMD 01 Code No. Units Title No of Hours No of Theoretical & seminars Practical Total weeks 1 Molecular genetics 5 2 7 3 2 Quality control and Quality 6 3 9 4 management 3 Molecular techniques 5 2 7 3 4 Recent markers of kidney and 5 2 7 3 liver diseases 5 Recent advances in cellular and 5 2 7 3 humoral immune responses 6 Neutrophils functions 5 2 7 2 7 Molecular haematology 5 2 7 2 Total 36 15 51 20 Code No. Unit Title No of Hours No of s Theoretical & seminars Practical Total weeks 1 General immunology 40 15 55 25 2 Clinical immunology 86 15 101 47 Total 126 30 156 72 Code No. Units Title No of Hours No of Theoretical & seminars Practical Total weeks 1 Cell structure 2 2 1 2 Molecular diagnostics 6 6 3 3 Basic principles in microbial ecology 3 3 2 4 Microbial genetics 8 8 4 5 Laboratory safety measures 6 4 10 4 6 Bacteriological detection of water contamination 2 2 1 11

CPMD 05 CPMD 04 7 Normal microbial flora of the human body 2 2 1 8 Recent methods of diagnosis 19 20 39 14 of pathogens affecting different body organs 9 Antibiotics and sensitivity 7 4 11 4 testing 10 Properties and pathogenesis and 6 8 14 5 control of viruses 11 Medical mycology 9 4 13 5 12 Infection control 6 6 3 Total 75 40 115 47 Code No. Code No. Units Title No of Hours No of Theoretical & seminars Practical Total weeks 1 Introduction to principles of 13 4 17 6 laboratory analysis and safety 2 Analytical techniques and 20 10 30 10 instrumentation 3 Laboratory operations 14 9 23 7 4 Analytes 20 14 34 10 5 Pathophysiology of different 20 18 38 10 organ 6 Molecular diagnostics and 14 4 14 7 genetics Total 60 160 50 Units Title No of Hours No of Theoretical & seminars Practical Total weeks 1 Anaemia 32 24 37 21 2 Immunhaematology and blood 34 20 54 10 blanking 3 Hemostasis and thrombosis 52 24 76 20 4 Myloid and lymphoid disorders 32 22 54 21 Total 150 90 240 72 11

4-Stakeholders 5- Programme admission requirements: Master degree in Clinical Pathology (Candidates must pass the final exam with at least 65%). 6- Regulations for progression and programme completion: At the end of 1 st academic year: a) Fulfillment of the log book. b) Pass examinations in the computer, statistics and molecular biology courses. 2 nd academic year: a) Perform creative MD thesis in of clinical Pathology: fulfillment of the supervisors report every 3 months. b) Fulfillment of the log book. c) Pass examination in the Immunology and one of the following courses: Microbiology course(cpmd 03), Clinical chemistry CPMD 04), Hematology (CPMD 05) according to specialty. 3 rd academic year: a) Perform a seminar about the thesis results. b) Acceptance of the MD thesis from judgment committee nominated by department council. 7- Evaluation of programme intended learning outcomes: Evaluator Tool Sample 1- Exams results Results analysis All the students Report 2- Students Questionnaires All the students 3-Graduates after achieving MSc degree Questionnaires group discussion 10 at least *- teaching staff. *- Technicians. Interviews *- Regional medical institutes Internet contact *- International medical institutes. Phone calls 10 at least *- other Governmental faculties Questionnaires *- Non governmental faculties 12

5-External Evaluator 6-Others(If Present) Hospital managers Questionnaires 8- References : A) Basic materials : Essential Books (Text Books): -george P., Redei(2008): encyclopedia in genetics, genomics, proteomics and informatics 3 rd edition -Alan E.H Emery and Robert F. Muller (1992): Element of medical genetics Student notes 8 th edition - Steven L. Gersen and Martha B. Keagle(1999) :The Principles of Clinical Cytogenetics -Abul K. Abbas, Andrew H. Lichtman, Shiv Pillai(2012): cellular and Molecular immunology -Tietz Textbook of Clinical Chemistry.BrutisCA and AshwoodE(Eds) 3rd Edition2006,WBSaunders,PhiladelphiaPA. -Clinical Chemistry:Principles,procedures,correlations Michael L.Bishop,Edward P.Fody,LarrySchoeff 5th Edition(Lippincott Williams&Wilkins)2010 -Victor Hoffbrand, Daniel Catovesky, Edward G.D.Tuddenham (2011) : PostgaduateHematology 6 th edition - Geo. F.B; Karen, C.C.; Janet, S.B. and Stephen, A.M.(2010): Medical Microbiology. 25th edition, McGraw-Hill Companies, USA. B) Suggested materials: -Self learning in library, high education library, digital library. -Browsing web sites of Clinical pathology : www.zu.edu.eg, Entrizepubmed -Medical journals.: Am J Clinical pathology, Br J Clinical pathology E. learning and E. BOOKS -Periodicals, Web Sites. Attendance of; Grand rounds, Conference attendance, Workshops, 13

Thesis discussion, Seminars 9-Supports for Candidates and their Learning: Candidates and their learning are supported in a number of ways: Printed copies of the programme (Candidates aware of the ILOs and requirement of the MD degree in Clinical microbiology. Availability of University central liberary. Availability of the Faculty postgraduate library. Availability of the Department Postgraduate library. Availability of the faculty digital library. Availability of the other educational resources. MD thesis Supervisors (three Staff members according to the research specialty for each candidate). Websites available in the department. 10-Methods used for improving the programme: Peer teaching observations and feedback to the programme management team and the coordinator (written reports at the end of the courses). Faculty appointed external examiners. Candidates' evaluation of teaching (Questionnaires). 11-Regulations of assessment by-laws of the MD degree postgraduate of the faculty of medicine: Computer course 1- Attendance of at least 75% of the teaching courses. 2- Log book fulfilled and approved by the head of the department. 14

12- Commette with responsibilitybfor monitoring and evaluating quality: Intrenal evaluators: 1-Prof.Dr MervatAzab (Head of Clinical Pathology Department). 3- Member from Quality unit in the faculty :Ass.Prof. of physiology(dalia Ibrahim AbdElaleem). External Evaluator: Prof. Dr. :Ikbal Abo Hashem Faculty of Medicine-Mansoura Univerty Tools Mark Percentage of the total mark Written exam 80 80% Oral and Practical exam 20 20 % Total marks Statistics course (MS) 4- Attendance of at least 75% of the teaching courses. 5- Log book fulfilled and approved by the head of the department. Percentage of the total mark % Mark Tools Written exam Total marks Molecular Biology course: 1- Pass the exam of the computer and statistics courses (at least 60% of total Mark). 2- Attendance of at least 75% of the teaching courses. 3- Log book fulfilled and approved by the head of the department. Percentage of the total mark Mark 80 20 Tools Written exam Oral and Practical exam Total marks Microbiology Course: 1- Pass the exam of the computer and statistics courses (at least 60% of total Mark). 2- Attendance of at least 75% of the teaching courses. 3- Log book fulfilled and approved by the head of the department. Percentage of the total mark 33.3% 33.3 % Mark Tools Written exam Oral exam 15

33.3% 300 Haematology Course: Practical exam Total marks 1- Pass the exam of the computer and statistics courses (at least 60% of total Mark). 2- Attendance of at least 75% of the teaching courses. 3- Log book fulfilled and approved by the head of the department. Percentage of the total mark 33.3% 33.3 % 33.3% 300 Clinical Chemistry Course: Mark Tools Written exam Oral exam Practical exam Total marks 1- Pass the exam of the computer and statistics courses (at least 60% of total Mark). 2- Attendance of at least 75% of the teaching courses. 3- Log book fulfilled and approved by the head of the department. Percentage of the total mark 33.3% 33.3 % 33.3% 300 Immunology Course: Mark Tools Written exam Oral exam Practical exam Total marks 1- Pass the exam of the computer and statistics courses (at least 60% of total Mark). 2- Attendance of at least 75% of the teaching courses. 3- Log book fulfilled and approved by the head of the department. Percentage of the total mark 33.3% 33.3 % 33.3% 300 Mark Tools Written exam Oral exam Practical exam Total marks NB: Examinations are conducted twice yearly (May and November). Thesis: *- Preregistration seminar *- Registration of the thesis title. *- Perform the thesis within at least 24 months of registration. *- After finishing the thesis Candidate perform a seminar about the thesis results. 16

*- progression reports are introduced by each supervisor (one every 3 months). *- Master thesis acceptance by the supervisors. *- MD thesis acceptance by the judgment committee in an advertised public session by three professors including one of the supervisors, one from the faculty and third from other faculty. *- Four copies of the thesis must be given to the postgraduate library. 13- Rules for awarding the MD Degree in Clinical pathology: Candidates must pass the computer, statistics and molecular biology(clin Path 9) courses exams (at least 60%) as a prerequisite for the registration of Immunology course(cl Path 10),one of the following g courses: Microbiology course(cl Path11)or Clinical chemistry(cl Path 12)or Hematology (Cl Path 13) and Thesis(Cl Path 14).. Candidates must pass the final exam of the chosen courses. Attendance of at least 75% of the teaching courses. Log book fulfilled and approved by the head of the department. Head of Clinical Pathology department: Prof. Dr/ MervatAzab 17