Martin B. Forstner, Ph.D.



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2014 Curriculum Vitae 1 Martin B. Forstner, Syracuse University Martin B. Forstner, Ph.D. Syracuse University Department of Physics Syracuse Biomaterials Institute Room 217 Syracuse, NY, 13244 USA Email: mbforstn@syr.edu Phone: (315) 443-3878 (office) Fax: (315) 443-9103 Web: http://physics.syr.edu/~mbforstn/ EMPLOYMENT Assistant Professor Physics Department Syracuse University, Syracuse, NY, USA Assistant Professor by Courtesy Biology Department Syracuse University, Syracuse, NY, USA Assistant Professor by Courtesy Department of Biomedical and Chemical Engineering Syracuse University, Syracuse, NY, USA 08/18/2008-present 10/01/2010-present 09/01/2011-present Postdoctoral Researcher 08/01/2003-07/31/2008 Department of Chemistry University of California, Berkeley, CA, USA Supervisor: Prof. Jay T. Groves Graduate Research Assistant 08/01/2002-06/30/2003 Institute for Experimental Physics I University of Leipzig, Germany Supervisor: Prof. Dr. Josef A. Käs Work was conducted at the University of Texas at Austin under co-supervision of Prof. Dr. Harry L. Swinney Graduate Research Assistant 01/11/1999-07/31/2002 University of Texas, Austin, TX, USA Center of Nonlinear Dynamics Supervisor: Josef A Käs EDUCATION Ph.D. Physics, Center for Nonlinear Dynamics 01/11/1999-05/17/2003 University of Texas, Austin, TX, USA

Curriculum Vitae 2 Martin B. Forstner, Syracuse University Dissertation Title: Motion of Nano-Objects in Langmuir Monolayers Thesis Advisors: Prof. Josef A. Käs, Prof. Harry L. Swinney Diploma in Physics (German M.S. equivalent) 09/20/1992-11/30/1998 University of Regensburg, Germany Thesis Title: Brownian and Anomalous Diffusion of Individual Amphiphilic Molecules in Langmuir Monolayers Thesis Advisor: Prof. Josef A. Käs RESEARCH INTERESTS Understanding quantitatively the dynamic interplay between spatio-temporal organization of biological and biomimetic interfaces and their respective functions using advanced biophotonic techniques. TEACHING EXPERIENCE Biological & Medical Physics (PHY 315) Physical Cell Biology (BIO/BME/CEN/CHE/PHY 635) Spring 2013 Falls 2012& 2013 Major Concepts of Physics II for Non Majors (PHY 102) Springs 2010 & 2011 Experimental Physics 1 & 2 (PHY 344/462) Falls 2009,2010 & 2011 Lab Section of Major Concepts of Physics II for Non Majors (PHY Spring 2009 102) Physics Journal Workshop (PHY 250) Spring 2009 Substitute Lectures in Undergraduate and Graduate Level Courses 2004-2008 Teaching Assistant for Physics for Engineering Students 2001 FUNDING Chancellor s Leadership Project, SU 2009 Transformative Alliance on Cellular Engineering (TrACE), Co-PI, $25k NSF CAREER, Non-Equilibrium Physics of Biological Interfaces, PI, $795k 2010-2015 MRI: Acquisition of a fluorescence activated cell sorter, Co-PI, $459k 2013-2016 AWARD NSF CAREER, Non-Equilibrium Physics of Biological Interfaces, 2010 PROFESSIONAL SERVICE Reviewer for: Langmuir Journal of Colloid and Interface Science Journal of Structural Biology 2004-present 2007-present

Curriculum Vitae 3 Martin B. Forstner, Syracuse University Biophysical Journal European Journal for Chemical Physics and Physical Chemistry Small ACS Nano Journal of the American Chemical Society 2010-present 2011-present 2012-present Co-organization of the conference on Assembly and Self-Assembly 2001 at the Interface of Biology, Chemistry and Physics in Il Ciocco, Italy Panel Reviewer for NSF, ad hoc reviewer for DoE PROFESSIONAL ASSOCIATIONS AND MEMBERSHIPS Biomaterials Institute Syracuse University, Syracuse, NY USA SB3: Structural Biology, Biochemistry and Biophysics Program Syracuse University, SUNY Upstate Medical School, SUNY College of Environmental Science and Forestry, Syracuse, NY USA Biophysical Society American Physical Society American Chemical Society New York Academy of Science American Association for the Advancement of Science Royal Chemical Society, GB The Optical Society 2008-present 1999-present 2002-present 2005-present 2008-present 2012-present 2013-present INVITED PRESENTATIONS AND TALKS Forstner, M. B., "Biomimetic Membranes in Basic Science and Application, ACS Meeting, Symposium on New Frontiers and Challenges in Biomaterials Analysis, New Orleans, 2013 Forstner, M. B., Dynamic Organization of Biomembranes, Seminar, Physics Department, Georgia Institute of Technology, 2013 Forstner, M. B., "Biomimetic Membranes in Basic Science and Application, 108th Topical Symposium on Recent Advances in Physics of the APS New York State section at Well s College, 2013 Forstner, M. B., "Fluid, yet structured: organization of bio-membranes", Colloquium, Science Department, Wells College, 2012 Forstner, M. B., "Fluid, yet structured: organization of bio-membranes", Colloquium, Chemistry Department, Union College, 2012

Curriculum Vitae 4 Martin B. Forstner, Syracuse University Forstner, M. B., "Fluid, yet structured: organization of bio-membranes", Colloquium, Physics Department, University of Delaware, 2012 Forstner, M. B., "Fluid, yet structured: organization of bio-membranes", Seminar, Physics Department, SUNY Buffalo, 2012 Forstner, M. B., "Fluid, yet structured: organization of bio-membranes", Colloquium, Physics Department, Rochester University, 2011 Forstner, M. B., "Fluid, yet structured: organization of bio-membranes", Colloquium, Biology Department, Syracuse University, 2010 Forstner, M. B., "Biological Membranes: from Single Molecules to Cells", Invited Lecture, Fall Meeting of the New York State Section of The American Association of Physics Teachers, Syracuse, 2009 Forstner, M. B., Membrane Structure of T Cells, Talk, Molecular Medicine Seminar Series, Cornell University School of Veterinary Medicine, 2009 Forstner, M. B., Lillemeier, B.F., Davis, M. M. & Groves, J. T., Activation Dependent Organization of T Cell Membranes, Talk, American Physical Society March Meeting, Pittsburgh, PA, 2009 Forstner, M. B., Lillemeier, B.F., Davis, M. M. & Groves, J. T., Activation Dependent Organization of T Cell Membranes, Talk, 7th New York Complex Matter Workshop, Cornell University, NY, 2008 Forstner, M. B., Lillemeier, B.F., Davis, M. M. & Groves, J. T., Different Lipid Anchors Recruit Proteins into Distinct Membrane Domains: A FCCS Study on Activated T-Cells., Talk, 234 th American Chemical Society National Meeting, New Orleans, LA, 2008 Forstner, M. B., Lillemeier, B.F., Davis, M. M. & Groves, J. T., Different Lipid Anchors Recruit Proteins into Distinct Membrane Domains: A FCCS Study on Activated T-Cells., Talk, 47 th Annual Meeting of the American Biophysical Society, Long Beach, CA, 2008 Forstner, M. B. & Groves, J. T., Membrane Spatial Organization and Cellular Signal Transduction., Talk, Conference on Biological Membranes and Membrane Proteins: Challenges for Theory and Experiment, City Park, UT, 2007 Forstner, M. B., Yee, C. K., Parikh, A. N. & Groves, J. T., Lipid Lateral Mobility and Membrane Phase Structure Modulation by Protein Binding., Poster, 232 nd American Chemical Society National Meeting, San Francisco, CA, 2006 Forstner, M. B., Yee, C. K., Parikh, A. N. & Groves, J. T., Sparse Protein Binding Alters Long-Range Lipid Mobility via Modulation of Phase Transition Behavior in Membranes., Talk, 45 th Annual Meeting of the American Biophysical Society, Salt Lake City, UT, 2006 Forstner, M. B., Martin, D. S., Navar, A. M. & Käs, J. A., Simultaneous Single-Particle Tracking and Visualization of Domain Structure on Lipid Monolayers., Oral Presentation, American Physical Society March Meeting, Austin, TX, 2003 Forstner, M. B., Martin, D. S. & Käs, J. A., Single Lipid Diffusion in Spatially Inhomogeneous Monolayers., Talk, US-Japan Workshop, Complexity Science, Austin, TX, 2002

Curriculum Vitae 5 Martin B. Forstner, Syracuse University Forstner, M. B., Martin, D. S. & Käs, J. A., Single Lipid Diffusion in Spatially Inhomogeneous Monolayers., Talk, 46 th Annual Meeting of the American Biophysical Society, San Francisco, CA, 2002 Forstner, M. B., Martin, D. S. & Käs, J. A., Anomalous Diffusion in a Single Lipid System? Minimal Requisites for Subdiffusion in Lipid Membranes., Poster, Conference on Assembly and Self-Assembly at the Interface of Biology, Chemistry and Physics, Il Ciocco, Italy, 2001 Forstner M. B., Martin D. S. & Käs J. A., Anomalous Diffusion in a Single Lipid System? Minimal Requisites for Subdiffusion in Lipid Membranes., Talk, 45 th Annual Meeting of the American Biophysical Society, Boston, MA, 2001 Forstner, M. B., Martin, D. S. & Käs, J. A., Anomalous Diffusion in a Single Lipid System? Minimal Requisites for Subdiffusion in Lipid Membranes., Poster, 40 th Annual Meeting of American Society for Cell Biology, San Francisco, CA, 2000 Forstner, M. B., Martin, D. S. & Käs, J. A., Anomalous Diffusion in a Single Lipid System? Minimal Requisites for Subdiffusion in Lipid Membranes., Talk, 44 th Annual Meeting of the American Biophysical Society, New Orleans, LA, 2000 Forstner, M. B., Martin, D. S. & Käs, J. A., Single Particle Tracking and the Observation of Anomalous Diffusion on Lipid Monolayers., Talk, 43 rd Annual Meeting of the American Biophysical Society, Baltimore, MD, 1999 PUBLICATIONS Badiambile, A. K. & Forstner, M. B., "Ion Induced Changes in Phosphoinositide Monolayers at Physiological Concentrations.", in preparation. Badiambile, A. K. & Forstner, M. B., "Calcium Modulated Compressibility of Phosphoinositide Monolayers.", in preparation. Degaga, E.K., & Forstner, M. B., Quantitfication of compositional changes in the nonerythroid membrane skeleton due to external forces, submitted. McCabe, I. P. & Forstner, M. B., "Polymer Supported Lipid Bilayers." Open Journal of Biophysics, 2013, 3(1A), pp. 59-69. Wilson, D. R., Zhang, N., Silvers, A.L., Forstner, M. B. & Bader, R. A., Synthesis and evaluation of cyclosporine A-loaded polysialic acid polycaprolactone micelles for rheumatoid arthritis, European Journal of Pharmaceutical Sciences, 2014, 51, pp 146-156, Published online: September 2013 McCabe, I. P. & Forstner, M. B., "Polymer Supported Lipid Bilayers." Open Journal of Biophysics, 2013, 3(1A), pp. 59-69. Rozovsky, S.; Forstner, M. B.; Sondermann H. & Groves, J. T., "Single Molecule Kinetics of ENTH Binding to Lipid Membranes." Journal of Physical Chemistry B, 2012, 116(17), pp. 5122-5131. Lillemeier, B. F.; Moertelmaier, M. A.; Forstner, M. B.; Huppa, J. B.; Groves, J. T. & Davis, M. M., "TCR and Lat are Expressed on Separate Protein Islands on T Cell Membranes and

Curriculum Vitae 6 Martin B. Forstner, Syracuse University Concatenate during Activation." Nature Immunology, 2010, 11(1), 90-96. Featured in: Van der Merwe, P. A.; Dunne, P. D.;Klenerman, D. & Day, S. J. News and Views: Taking T cells beyond the diffraction limit, Nature Immunology, 2010, 11(1), 51-52. Rabuka, D.; Forstner, M. B.; Groves, J. T. & Bertozzi, C. R., Non-Covalent Cell Surface Engineering: Incorporation of Bioactive Synthetic Glycopolymers into Cellular Membranes. Journal of the American Chemical Society, 2008, 130, (18), 5947-5953. Forstner, M. B.; Martin, D.; Ruckerl, F.; Käs, J. A. & Selle, C., Attractive Membrane Domains Control Lateral Diffusion. Physical Review E, 2008, 77, 051906. Groves, J. T.; Parthasarathy, R. & Forstner, M. B., Fluorescence Imaging of Membrane Dynamics. Annual Review of Biomedical Engineering, 2008, 10, 311-338. Paulick, M. G.; Forstner, M. B.; Groves, J. T. & Bertozzi, C. R., A Chemical Approach to Unraveling the Biological Function of the Glycosylphosphatidylinositol Anchor. Proceedings of the National Academy of Sciences of the United States of America, 2007, 129, (37), 11543-11550. Paulick, M. G.; Wise, A. R.; Forstner, M. B.; Groves, J. T. & Bertozzi, C. R., Synthetic Analogues of Glycosylphosphatidylinositol-Anchored Proteins and their Behavior in Supported Lipid Bilayers. Journal of the American Chemical Society, 2007, 129, (37), 11543-11550. Forstner, M. B.; Yee, C. K.; Parikh, A. N. & Groves, J. T., Lipid Lateral Mobility and Membrane Phase Structure Modulation by Protein Binding. Journal of the American Chemical Society, 2006, 128, (47), 15221-15227. Selle, C.; Ruckerl, F.; Martin, D. S.; Forstner, M. B. & Käs, J. A., Measurement of Diffusion in Langmuir Monolayers by Single-Particle Tracking. Physical Chemistry Chemical Physics 2004, 6, (24), 5535-5542. Forstner, M. B.; Martin, D. S.; Navar, A. M. & Kas, J. A., Simultaneous Single-Particle Tracking and Visualization of Domain Structure on Lipid Monolayers. Langmuir 2003, 19, (12), 4876-4879. Martin, D. S.; Forstner, M. B. & Kas, J. A., Apparent Subdiffusion Inherent to Single Particle Tracking. Biophysical Journal 2002, 83, (4), 2109-2117. Forstner, M. B.; Kas, J. A. & Martin, D., Single Lipid Diffusion in Langmuir Monolayers. Langmuir 2001, 17, (3), 567-570. SCIENTISTS MENTORED Postdoctoral Researchers Dr. Lauren O Neil 2009-2010 now: Assistant Professor, Wells College, NY Graduate Students Adolphe Kadazi Badiambile 2009- present Eleni Knife Degaga 2009- present

Curriculum Vitae 7 Martin B. Forstner, Syracuse University Ian McCabe 2009- present David Harbage 2010- Spring 2011 (left with M.S) Kathleen Kelly 2010- present Rachel Meredith 2012- Spring 2013 Undergraduate Students Pauline Hua 2009-2010 now: Downstate Medical School ChaoJie Zhen 2010-Spring 2011 now: Weill Cornell Medical College Bridget Lally REU - 2010 Shane Dunn 2010-present Sundus Mian 2010-Spring 2011 Tianiy Zhou 2010-Spring 2011 David Kopel 2010-present Navjyot Singh Parmar 2010-Spring 2011 Lexus Johnson REU 2011 Zoe Kazzaz Fall 2012 present Ismet Yesilada Spring 2012 Marcel Lachance Summer 2013 Damian Beasock Fall 2013 present