3rd Annual Vit-Buckle Society Meeting

March 19-21, 2015 Fontainebleau MiaMi beach 3rd Annual Vit-Buckle Society Meeting 2015 accreditation and credit Designation This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education through the joint providership of William Beaumont Hospital, Medical Conference Planners, Inc. and the Vit-Buckle Society. William Beaumont Hospital is accredited by the ACCME to provide continuing medical education for physicians. William Beaumont Hospital designates this live activity for a maximum of 11.25 AMA PRA Category 1 Credit(s). Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Organizing COMMiTTEE THoMAS A. AlBInI, MD r.v. PAul CHAn, MD DErEk y. kunimoto, MD, JD geeta A. lalwani, MD AnDrEW A. MoSHfEgHI, MD, MBA AuDInA M. BErroCAl, MD JoHn W. kitchens, MD r. ross lakhanpal, MD CHArlES W. MAngo, MD CHArlES C. Wykoff, MD, PhD................................................................................................................... Bienvenido TO VBS ViCE 2015! If you are a VBS veteran, we are delighted to welcome you back. If you are new to the VBS, you are in for a treat a retinal meeting with a unique format: a forum aimed at energetic, up and coming vitreoretinal specialists and surgeons willing to discuss medical practices and surgical techniques in an open and highly interactive environment among colleagues. The distinction between faculty and audience is gone. Everyone is a participant. Everyone is a speaker. Be prepared to offer up your ideas, insights and challenges by interacting with presenters, moderators, industry... everyone. you will never attend a meeting that better fosters constant interaction and engagement. This meeting is made possible by your experiences and knowledge as well as the support of the companies listed. Their continued support of this forum geared for lively exchange and discussion is testament to their dedication to our profession. now, share your experiences, voice your concerns and thoughts, and most importantly leave this meeting feeling that you contributed and learned something. gracias for coming back to Miami, we look forward to our time together! THE VBS VICE ORGANIZING COMMITTEE V B S V I C E 2 015 3

Faculty robert l. avery, MD California retina Consultants Santa Barbara, CA caroline r. baumal, MD Tufts Medical Center Boston, MA chris bergstrom, MD, od Emory Eye Center Atlanta, ga Maria h. berrocal, MD university of Puerto rico San Juan, Pr harit K. bhatt, MD Illinois Eye and Ear Infirmary Chicago, Il David M. brown, MD retina Consultants of Houston Houston, TX antonio capone, Jr., MD Associated retinal Consultants/ William Beaumont Hospital royal oak, MI Steve charles, MD Charles retina Institute Memphis, Tn David r. chow, MD university of Toronto Toronto, on, Canada Donald J. D amico, MD Weill Cornell Medical College/ new york-presbyterian new york, ny David a. eichenbaum, MD retina-vitreous Associates of florida St. Petersburg, fl andres emanuelli, MD Arecibo, Pr christiane i. Falkner-radler, MD ludwig Boltzmann Institute of retinology and Biomicroscopic laser Surgery rudolf foundation Clinic Vienna, Austria harry W. Flynn, Jr., MD Bascom Palmer Eye Institute Miami, fl Matteo Forlini, MD university of Modena Modena, Italy Jans Fromow-Guerra, MD, PhD Hospital Dr. luis Sanchez Bulnes Asociación Para Evitar la Ceguera en México Mexico City, Mexico Gerardo Garcia-aguirre, MD Hospital Dr. luis Sanchez Bulnes Asociación Para Evitar la Ceguera en México Mexico City, Mexico Victor h. Gonzalez, MD Valley retina Institute McAllen, TX evangelos S. Gragoudas, MD Massachusetts Eye and Ear Infirmary Boston, MA ninel Z. Gregori, MD Bascom Palmer Eye Institute Miami, fl Paul hahn, MD, PhD Duke Eye Center Durham, nc lawrence S. halperin, MD retina group of florida Boca raton, fl J. William harbour, MD Bascom Palmer Eye Institute Miami, fl tarek S. hassan, MD Associated retinal Consultants/ William Beaumont Hospital royal oak, MI Dianna l. hoskins Cincinnati Eye Institute Cincinnati, oh G. baker hubbard, MD Emory Eye Center Atlanta, ga bernard r. hurley, MD university of ottawa Eye Institute ottawa, Canada Jonathan Jonish, MD long Island Vitreoretinal Consultants great neck, ny rahul n. Khurana, MD uc San francisco, CA northern California retina Vitreous Associates San Mateo, CA ivana K. Kim, MD Massachusetts Eye and Ear Infirmary Boston, MA John W. Kitchens, MD retina Associates of kentucky lexington, ky 4 V B S V I C E 2 015

Derek Y. Kunimoto, MD, JD retinal Consultants of Arizona Phoenix, AZ linda a. lam, MD usc keck School of Medicine los Angeles, CA Yannek i. leiderman, MD university of Illinois, College of Medicine at Chicago Chicago, Il theodore leng, MD Stanford School of Medicine Palo Alto, CA Phoebe lin, MD, PhD Casey Eye Institute oregon Health and Science university Portland, or tamer h. Mahmoud, MD, PhD Duke university Eye Center Durham, nc James c. Major, Jr., MD, PhD retina Consultants of Houston Houston, TX efrem D. Mandelcorn, MD Toronto Western Hospital university of Toronto Toronto, on, Canada tara a. Mccannel, MD, PhD Jules Stein Eye Institute/uClA los Angeles, CA Virgilio Morales-canton, MD Hospital Dr. luis Sanchez Bulnes Asociación Para Evitar la Ceguera en México Mexico City, Mexico andrew a. Moshfeghi, MD, Mba usc keck School of Medicine los Angeles, CA Prithvi Mruthyunjaya, MD Duke Eye Center Durham, nc timothy G. Murray, MD, Mba Murray ocular oncology and retina Miami, fl carmen rosina negrin, MD Medicalnet Santo Domingo, Dr lisa c. olmos de Koo, MD, Mba usc keck School of Medicine los Angeles, CA Kirk h. Packo, MD rush university Medical Center Chicago, Il Samir Patel, MD ophthotech Corporation new york, ny carmen a. Puliafito, MD, Mba usc keck School of Medicine los Angeles, CA hugo Quiroz-Mercado, MD Denver Health Medical Center university of Colorado School of Medicine Denver, Co aleksandra V. rachitskaya, MD Cole Eye Institute Cleveland Clinic Cleveland, oh carl D. regillo MD Mid Atlantic retina/wills Eye Institute Philadelphia, PA Philip J. rosenfeld, MD, PhD Bascom Palmer Eye Institute Miami, fl andrew M. Schimel, MD florida International university Wertheim College of Medicine Miami, fl Gaurav K. Shah, MD retina Institute St. louis St. louis, Mo robert a. Sisk, MD Cincinnati Eye Institute Cincinnati, oh lucia Sobrin, MD, MPh Massachusetts Eye and Ear Infirmary Boston, MA Sunil K. Srivastava, MD Cole Eye Institute Cleveland Clinic Cleveland, oh charles c. Wykoff, MD, PhD retina Consultants of Houston Houston, TX Deepa Yoganathan, MD university of Toronto Toronto, on, Canada David n. Zacks, MD, PhD kellogg Eye Center university of Michigan Ann Arbor, MI V B S V I C E 2 015 5

................................................................................................................... VBS Keynote SpeAKer FriDaY, March 20 2:30 PM From Concept to reality: What i ve Learned along the Way CarMEn a. PuLiaFiTO, MD, MBa Carmen A. Puliafito, MD, MBA is the dean of the keck School of Medicine of usc and holder of the May S. and John Hooval Dean s Chair in Medicine. Prior to leading the keck School, he was director of the Bascom Palmer Eye Institute and chair of the Department of ophthalmology of the university of Miami Miller School of Medicine. Previously, he was founding director of the new England Eye Center and chair of the Department of ophthalmology at Tufts university. Throughout his career Dr. Puliafito has been an innovator, most recently participating in the introduction of bevacizumab (Avastin) for the treatment of retinal disorders. He was the first to describe the use of the semiconductor diode laser for retinal photo - coagulation, and he did pioneering basic science research in excimer laser photoablation and optical breakdown and photodisruption. He established a major optical imaging program while at the university of Miami, and is still actively working with his laboratory team investigating novel retinal imaging approaches at usc, most notably an initial description of the novel technique of photo acoustic ophthalmoscopy. Dr. Puliafito is recognized as co-inventor of the technology of optical coherence tomography (oct) and with being the first ophthalmologist to use this technology to study the human macula in health and disease. from the first publication about oct in 1991 to the implementation of the first clinical system two years later, Dr. Puliafito has led in the development of oct technology a technology which has truly revolutionized retinal practice and made a real difference for both patients and retinal specialists. from a single system at the new England Eye Center at Tufts university School of Medicine in 1993, oct has grown to have a global impact, now with more than 20,000 systems in use every day throughout the world. for his work on oct, Dr. Puliafito was awarded (along with James fujimoto and Eric Swanson) the 2002 rank Prize the world s most prestigious award in optoelectronics. In 2012, also for his work on oct, Dr. Puliafito was awarded (along with James fujimoto, Eric Swanson, David Huang and Joel Schuman) the Champalimaud Vision Award, often called the nobel Prize for Vision. Keynote Speaker Honorees A graduate of Harvard College and Harvard Medical 2013 Stanley Chang, MD School, Dr. Puliafito earned his MBA from the Wharton 2014 William S. Tasman, MD School of Business of the university of Pennsylvania. 6 V B S V I C E 2 015

.................................................................................................................. VBS LIFetIMe MentorSHIp AWArD SaturDaY, March 21 12:00 PM Proton Beam irradiation of uveal Melanomas: The First Forty Years EVangELOS gragoudas, MD Dr. Evangelos gragoudas has been the Director of retina Service at the Massachusetts Eye and Ear Infirmary since 1985 and has trained more that 100 clinical fellows and over 50 research fellows from all over the world. He is a leading clinician-researcher and has spent over 25 years investigating treatments for intraocular tumors and macular disorders. He is considered a world authority on the diagnosis and manage - ment of ocular tumors and is world-renowned for his groundbreaking work in the use of proton irradiation to treat intraocular melanoma. Dr. gragoudas has long-standing interest in photodynamic therapy (PDT) for the treatment of ocular tumors and ocular neovascularization. He collaborated with Dr. Joan W. Miller on preclinical studies of PDT using the light-sensitive dye, Verteporfin, for the treatment of choroidal neovascularization. Dr. gragoudas was instrumental in designing and executing the early clinical studies and was an integral member of the study group and writing group for the large clinical trials. Based on these large clinical trials, photodynamic therapy using Verteporfin was approved by the health authorities throughout the world and became the first widely used treatment for neovascular retinal disease that effectively slowed disease progression. Dr. gragoudas also pioneered work on ocular angiogenesis and anti-angiogenesis therapy. He worked with a group of ophthalmologists, including Drs. Joan Miller, Tony Adamis, Pat D Amore and others in collaboration with the laboratory of noted angiogenesis discoverer, Dr. Judah folkman. This team first demonstrated the critical role of vascular endothelial growth factor (VEgf) in ocular neovascularization and went on to develop therapies targeting VEgf. Macugen, the first compound based on this approach effectively slowed the progression of age-related macular degeneration (AMD), the most frequent cause of blindness in patients over age 60. A second-generation pharma - ceutical, lucentis was found to result in vision improvement for the first time in approximately one-third of patients with neovascular AMD who underwent treatment. Dr. gragoudas completed his medical training in Athens, greece and his ophthalmology residency at Boston university School of Medicine. Dr. gragoudas has published over 200 articles in peer-reviewed journals and written or authored more than 100 chapters, reviews, and books; he lectures nationally and internationally. Lifetime Mentorship award Honorees 2013 Allan E. kreiger, MD 2014 Harry W. flynn, Jr., MD V B S V I C E 2 015 7

Thursday, March 19 6:00 PM-9:00 PM FeLLoWS ForAy (a non-cme event) fleur De lis Ballroom SEE SEPARATE PROGRAM Friday, March 20 8:00 am-6:00 PM registration fleur De lis Ballroom foyer 8:00-9:00 am Breakfast fontaine Ballroom 8:00 am-6:00 PM Exhibits fontaine Ballroom 8:55 am-6:00 PM Scientific Sessions fleur De lis Ballroom 8:55-9:00 am Opening remarks Charles C. Wykoff, MD, PhD 9:00-11:00 am SCIENTIFIC SESSION 1: Surgery outside of the Box 120 Moderators: g. Baker Hubbard, MD, David M. Brown, MD, Donald J. D Amico, MD 9:00 am Pneumoves Efrem D. Mandelcorn, MD 9:15 am intraoperative OCT Christiane I. falkner-radler, MD 9:25 am intraoperative OCT Sunil k. Srivastava, MD 9:35 am Trauma and intraocular Foreign Bodies Aleksandra V. rachitskaya, MD 9:45 am Lessons from the retinal Detachment Following ruptured globe Trenches Deepa yoganathan, MD 9:55 am 27 gauge: gimmick or game Changer Theodore leng, MD 10:10 am Chandelier Buckles: initial Experience Tamer H. Mahmoud, MD, PhD 10:20 am Pole to Pole Surgery Matteo forlini, MD 10:30 am Chorioretinal Biopsies and Endoresections Phoebe lin, MD, PhD 10:45 am Creating the Bionic Eye: Surgical Pearls for implanting a retinal Prosthesis lisa C. olmos de koo, MD, MBA ninel Z. gregori, MD 8 V B S V I C E 2 015

11:00-11:30 am Break 11:30 am-1:15 PM SCIENTIFIC SESSION 2: Medical retina Debates Moderators: robert l. Avery, MD, Carl D. regillo, MD, Philip J. rosenfeld, MD, PhD, Charles C. Wykoff, MD, PhD 11:30 am The 2015 revised guidelines for intravitreal injection Harry W. flynn, Jr., MD SAFety ISSUeS 11:45 am using T/E to improve Safety Carl D. regillo, MD 11:55 am Systemic Safety Concerns with anti-vegf agents robert l. Avery, MD 12:15 PM Macular atrophy after anti-vegf Therapy Moderators: Andrew A. Moshfeghi, MD, MBA and Philip J. rosenfeld, MD, PhD DMe: IntereStInG AnD CoMpLeX CASe MAnAGeMent 12:35 PM Panelists: Antonio Capone, Jr., MD, David A. Eichenbaum, MD, Victor H. gonzalez, MD, Andrew A. Moshfeghi, MD, MBA, Charles C. Wykoff, MD, PhD GenetICS 1:00 PM The Current role of genetic Testing in retina Practice lucia Sobrin, MD, MPH 1:15-2:30 PM Lunch 1:30-2:20 PM industry Presentations (a non-cme event) Moderator: geeta A. lalwani, MD Alcon laboratories, Inc. Allergan, Inc. Bausch + lomb Dutch ophthalmic usa genentech, Inc. Insight Instruments, Inc. oculus Surgical Inc. Quantel Medical regeneron Pharmaceuticals, Inc. Synergetics, Inc. 2:30-3:15 PM Keynote LeCtUre From Concept to reality: What i ve Learned along the Way one on one Interview: Carmen A. Puliafito, MD, MBA, interviewed by John W. kitchens, MD 3:15-4:00 PM SCIENTIFIC SESSION 3: Bench to Bedside Moderator: Derek y. kunimoto, MD, JD Panelists: Steve Charles, MD, Samir Patel, MD, Carmen A. Puliafito, MD, MBA, David n. Zacks, MD, PhD 4:00-4:30 PM Break V B S V I C E 2 015 9

4:30-6:00 PM SCIENTIFIC SESSION 4: Surgical Complications Moderators: David r. Chow, MD, Tarek S. Hassan, MD, kirk H. Packo, MD, Andrew M. Schimel, MD 4:30 PM get Back in There! an unusual Postoperative Complication Jonathan Jonisch, MD 4:45 PM Headache after Macular Hole repair Harit k. Bhatt, MD 5:00-6:00 PM Surgical Complications Panel Discussion Moderator: Andrew M. Schimel, MD Panelists: David r. Chow, MD, Tarek S. Hassan, MD, kirk H. Packo, MD 6:00 PM adjourn 8:00-11:00 PM Dinner at Liv Saturday, March 21 8:00 am-4:05 PM registration fleur De lis Ballroom foyer 8:00-9:00 am Breakfast fontaine Ballroom 8:00 am-2:45 PM Exhibits fontaine Ballroom 9:00 am-4:05 PM Scientific Sessions fleur De lis Ballroom 9:00-11:00 am SCIENTIFIC SESSION 5: rd Management Moderators: Antonio Capone, Jr., MD, yannek I. leiderman, MD, PhD, Carl D. regillo, MD 9:00 am The right Way to Do a Pr Caroline r. Baumal, MD 9:12 am Valved Cannulae Keepin it Quiet Paul Hahn, MD, PhD 9:24 am Tactics for Efficient repair of Diabetic TrD The Vitrectomy Probe as Swiss army Knife yannek I. leiderman, MD 9:36 am Check Out This Baby! James C. Major, Jr., MD, PhD 9:48 am Diabetic Vitrectomy: How to Survive if You re not Maria Berrocal robert A. Sisk, MD 10:00 am The art of and the Practical approach to PVr Management How to get 90% anatomic Success with Patient and referral Smiles kirk H. Packo, MD 10 V B S V I C E 2 015

10:20 am Scleral Fixation with gore-tex and an akreos iol rahul n. khurana, MD 10:30-11:00 am rapid FIre SeCtIon Moderators: Caroline r. Baumal, MD, linda A. lam, MD, yannek I. leiderman, MD 10:30 am relaxing retinectomy in Posterior Break Paul Hahn, MD, PhD 10:35 am rd Management Decisions gaurav k. Shah, MD 11:00-11:30 am Break 11:30 am-12:00 PM SCIENTIFIC SESSION 6: ocular oncology for every retina Specialist: Case Discussions Moderators: Prithvi Mruthyunjaya, MD and Timothy g. Murray, MD, MBA Panelists: Chris Bergstrom, MD, od, Evangelos S. gragoudas, MD, J. William Harbour, MD, Ivana k. kim, MD, Tara A. McCannel, MD, PhD 12:00 PM VBS LIFetIMe MentorSHIp AWArD LeCtUre Proton Beam irradiation of uveal Melanomas: The First Forty Years Introduction: r.v. Paul Chan, MD recipient: Evangelos S. gragoudas, MD 12:45-2:45 PM Lunch/Wetlab 2:45-3:15 PM SCIENTIFIC SESSION 7: Coding: Aggressive vs. Conservative Moderators: lawrence S. Halperin, MD and John W. kitchens, MD Panelist: Dianna l. Hoskins (Director Patient Accounts, Cincinnati Eye Institute) 2:45-3:15 Coding Discussion John W. kitchens, MD, lawrence S. Halperin, MD, and Dianna l. Hoskins 3:15-4:00 PM SCIENTIFIC SESSION 8: pan-american: Broaden your Horizons Moderators: Maria H. Berrocal, MD, Virgilio Morales-Canton, MD, Bernard r. Hurley, MD Panelists: Andres Emanuelli, MD, Jans fromow-guerra, MD, PhD, gerardo garcia-aguirre, MD, Carmen rosina negrin, MD, Hugo Quiroz-Mercado, MD 4:00-4:05 PM Closing remarks Thomas A. Albini, MD 7 :00 PM-MiDniGht Dinner and awards Ceremony fleur de lis and fontaine Ballrooms Entertainment provided by Bad Habits The EyeDocs of rock! V B S V I C E 2 015 11

THIS CME ACTIVITY IS SUPPORTED BY EDUCATIONAL GRANTS FROM: Alcon Laboratories, Inc. Regeneron Pharmaceuticals, Inc. Exhibitors the Vit-buckle Society gratefully acknowledges generous contributions from the following companies: SaPPHirE genentech, Inc. PLaTinuM Allergan, Inc. regeneron Pharmaceuticals, Inc. Synergetics, Inc. gold Alcon laboratories, Inc. Bausch + lomb Dutch ophthalmic usa Insight Instruments, Inc. oculus Surgical, Inc. Quantel Medical Alimera Sciences Carl Zeiss Meditec, Inc. Medone Surgical, Inc. notal Vision retina Today SiLVEr Santen, Inc. Thrombogenics, Inc. Topcon Medical Systems VisionCare ophthalmic Technologies, Inc. MEDiCaL COnFErEnCE PLannErS, inc. 914-722-0664 vbs@medconfs.com www.medconfs.com