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Substantial evidence supports the conclusion that these drugs, when used as directed in labeling, can prolong the QT interval and can have a risk of Torsdes de pointes (TdP) in some patients. Generic Name Brand Names Drug Class Therapeutic Use TdP Risk Category Risk Category Route Amiodarone Cordarone, Pacerone, Nexterone Anti-aric, Anagrelide Agrylin, Xagrid Phosphodiestera se 3 inhibitor Thrombocythemia Arsenic trioxide Trisenox Anti-cancer Leukemia Azithromycin Zithromax, Zmax Antibiotic Bacterial infection, Chloroquine Aralen Anti-malarial Malaria infection Chlorpromazine Thorazine, Largactil, Megaphen Anti-psychotic / Anti-emetic Schizophrenia/ nausea,, suppository

Citalopram Celexa, Cipramil Anti-depressant, SSRI Depression Ciprofloxacin Cipro, Cipro- XR, Neofloxin Antibiotic Bacterial infection, Clarithromycin Biaxin, Prevpac Antibiotic Bacterial infection Cocaine Cocaine Local anesthetic Topical anesthetic topical Disopyramide Norpace Anti-aric Dofetilide Tikosyn Anti-aric Dronedarone Multaq Anti-aric Atrial Fibrillation

Droperidol Inapsine, Droleptan, Dridol, Xomolix Anti-psychotic / Anti-emetic Anesthesia adjunct, nausea Erythromycin E.E.S., Robimycin, EMycin, Erymax, Ery- Tab, Eryc Ranbaxy, Erypar, Eryped, Erythrocin Stearate Filmtab, Erythrocot, E-Base, Erythroped, Ilosone, MY- E, Pediamycin, Zineryt, Abboticin, Abboticin-ES, Erycin, PCE Dispertab, Stiemycine, Acnasol, Tiloryth Antibiotic Bacterial infection; increase GI motility,

Escitalopram Cipralex, Lexapro, Nexito, Anxiset-E (India), Exodus (Brazil), Esto (Israel), Seroplex, Elicea, Lexamil, Lexam, Entact (Greece), Losita (Bangladesh), Reposil (Chile), Animaxen (Colombia), Esitalo (Australia), Lexamil (South Africa) Anti-depressant, SSRI Major depression/ Anxiety disorders Flecainide Tambocor, Almarytm, Apocard, Ecrinal, Flécaine Anti-aric

Halofantrine Halfan Anti-malarial Malaria infection Haloperidol Haldol (US & UK), Aloperidin, Bioperidolo, Brotopon, Dozic, Duraperidol (Germany), Einalon S, Eukystol, Halosten, Keselan, Linton, Peluces, Serenace, Serenase, Sigaperidol Anti-psychotic Schizophrenia, agitation, Ibutilide Corvert Anti-aric Levofloxacin Levaquin, Tavanic Antibiotic Bacterial infection,

Methadone Dolophine, Symoron, Amidone, Methadose, Physeptone, Heptadon Opiate Pain control, narcotic dependence, Moxifloxacin Avelox, Avalox, Avelon Antibiotic Bacterial infection, Ondansetron Zofran, Anset, Ondemet, Zuplenz, Emetron, Ondavell, Emeset, Ondisolv, Setronax Anti-emetic Nausea, vomiting, Pentamidine NebuPent, Pentam Antibiotic Pneumocystis pneumonia, inhaled Pimozide Orap Anti-psychotic Tourette's tics

Procainamide (Oral off US mkt) Pronestyl, Procan Anti-aric Quinidine Quinaglute, Duraquin, Quinact, Quinidex, Cin-Quin, Quinora Anti-aric, Sevoflurane Ulane, Sojourn Anesthetic, general Anesthesia inhaled Sotalol Betapace, Sotalex, Sotacor Anti-aric Thioridazine Mellaril, Novoridazine, Thioril Anti-psychotic Schizophrenia Vandetanib Caprelsa Anti-cancer Thyroid cancer