Anne M. Hudak, M.D., M.S.C.S.

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1 Anne M. Hudak, M.D., M.S.C.S. OFFICE ADDRESS Department of Physical Medicine and Rehabilitation Virginia Commonwealth University Richmond, VA EDUCATION 07/06 6/09 Masters of Science University of Texas Southwestern Graduate School of Biomedical Sciences 09/86 06/90 Doctorate of Medicine State University of New York Health Science Center at Brooklyn Brooklyn, NY 09/82-05/86 Bachelor of Science State University of New York at Albany Albany, NY POST-GRADUATE TRAINING APPOINTMENTS 07/00 07/01 Clinical Fellowship, Brain Injury Rehabilitation Kaiser Foundation Rehabilitation Center Vallejo, CA 07/97 06/00 Residency, Physical Medicine and Rehabilitation The University of Texas Southwestern Medical Center at Dallas 12/93 06/94 Chief Resident, Anesthesiology 07/91 06/94 Residency, Anesthesiology The Mount Sinai Medical Center NY, NY 07/90 06/91 Internship, Internal Medicine The Long Island College Hospital Brooklyn, NY CERTIFICATION 2011 Recertification, American Board of Physical Medicine and Rehabilitation

2 2001 Diplomate, American Board of Physical Medicine and Rehabilitation 1997 Diplomate, American Board of Anesthesiology 1991 Diplomate, National Board of Medical Examiners APPOINTMENTS 10/11-present 09/11-present Attending Staff Medical Director of Polytrauma Network Site Hunter Holmes McGuire Veterans Administration Medical Center Richmond, VA Associate Professor Virginia Commonwealth University Richmond, VA 11/01 8/11 Assistant Professor 11/01-6/06 Medical Director of Brinlee Creek Ranch Pate Rehabilitation 07/01 09/01 Kaiser Foundation Rehabilitation Center Vallejo, CA 07/94 07/96 Attending Anesthesiologist Long Island Jewish Medical Center New Hyde Park, NY AWARDS 1999 First Annual Physical Medicine and Rehabilitation Scientific Day, University of Texas Southwestern Medical Center at Dallas Outstanding Research Presentation NIH funded Clinical Scholar NIH K12 RR023251, KL2-RR PROFESSIONAL SOCIETY MEMBERSHIPS American Academy of Physical Medicine and Rehabilitation Brain Injury Special Interest Group

3 INVITED COMMITTEES March/April 2011 May 2010 May 2009 May 2008 Feb 2003 Reviewer for 2011 Annual Assembly Research Abstracts AAPM&R Annual Assembly Oral Board Examiner American Board of PM&R Oral Board Examiner American Board of PM&R Oral Board Examiner American Board of PM&R National Institute on Disability and Rehabilitation Research Field Initiated Grants, invited reviewer COMMITTEES 05/ /2011 Resident Education Committee 12/2009-3/2011 Surgical Ambulatory Care Committee Parkland Memorial Hospital 1/ /2011 Research Committee 6/2003-7/2006 Faculty Senate 7/ /2011 Trauma Executive Board Parkland Memorial Hospital /2001 Education Committee Kaiser Foundation Rehabilitation Center, Vallejo, CA 07/99 06/2000 Resident Member, Research Committee The at Dallas, RESEARCH 06/08 8/11 Depression in Traumatic Brain Injury: a Feasibility Trial -Enrollment Closed

4 04/08 8/11 Traumatic Brain Injury Clinic Registry Database -Enrollment Closed 06/05 12/07 Biomarkers - "Biomarkers of traumatic brain injury: Outcome predictors" 06/05 12/07 Diffuse Tensor Imaging -" Evaluation of Diffuse Axonal Injury in Patients with Traumatic Brain Injury Using Diffusion Tensor Imaging" 09/03-01/05 CENA713BUS11. "A 12-week, prospective, double-blind, placebo-controlled, multi-center study evaluating the efficacy and safety of Exelon 3 to 6 mg/day in patients with traumatic brain injury (TBI) with persistent cognitive deficits" and "A 26-week, open-label Extension to Protocol No. CENA713BUS11 07/03-06/08 NIH National Traumatic Brain Injury Clinical Trials Network. Grant #U01 HD Investigator 10/02-08/11 NIDRR North Texas Traumatic Brain Injury Model System. Grant #H133A Investigator; site coordinator for Parkland Memorial Hospital. 07/00 09/01 Effectiveness of mild traumatic brain injury clinic on patient satisfaction. 01/98 12/99 Development of the Parkland Agitation Scale 09/93 09/94 Examination of various anesthetics release in on excitatory neurotransmitter rat model of global reversible ischemia 09/89 05/90 -Localization of high affinity glial cell binding site for Lindane -Glutamine synthetase activity measured using ion exchange columns under a variety of in vivo conditions GRANTS K23 HD A1 07/11-06/15 Role: PI NICHD Exercise Training in Depressed Traumatic Brain Injury (TBI) Survivors KL2 RR Packer (PI) 6/1/08-5/31/09 Role: Co-Investigator NIH/NCRR Depression in Traumatic Brain Injury: a Feasibility Trial Role: Pilot Award Recipient PI

5 UTSW Clinical Scholars Program -completed 07/06-06/09 PI: Milton Packer, MD Grant Title: UT Southwestern Clinical Science Scholars Program Grant Number: NIH K12 RR Project Dates: 9/1/05-07/31/10 PI: Milton Packer, MD Grant Title: North and Central Texas Clinical and Translational Science Initiative Grant Number: 1 KL2 RR Project Dates: 09/17/07-05/31/12 PUBLICATIONS Original Research (In Chronological Order) 1. Casthely PA, Yoganathan D, Karyanis B, Karyanis B, Salem M, Yoganathan T, Komer C, Uribe M, Sclafani S, Hudak A. Histamine blockade and cardiovascular changes following heparin administration during cardiac surgery. J Cardiothorac Anesth (6): PMID Hill RA, Mateo F, Hudak A. Transient exacerbation of tuberculous lymphadenitits during chemotherapy in patients with AIDS. Clin Infect Dis. 1994; 19(4): PMID Hudak A, Konstadt SN. Aortic intussusception: a rare complication of aortic dissection. Anesthesiology. 1995; 82(5): PMID Hudak, A, K. Trivdei, CR Harper, K Booker, RR Caesar, M Agostini, PC Van Ness, R Diaz-Arrastia. Evaluation of seizure-like episodes in survivors of moderate and severe traumatic brain injury. J Head Trauma Rehabil (4): PMID Hudak, A, Caesar, R, Frol, A, Krueger, K, Harper, CR, Temkin, NR, Dikmen, SS, Carlile, M, Madden, C, Diaz-Arrastia, R. Functional outcome scales in traumatic brain injury: a comparison of the Glasgow Outcome Scale (Extended) and the Functional Status Examination. J Neurotrauma (11): PMID Marquez de la Plata, C., Hewlitt, M., de Oliveira, A., Hudak, A., Harper, C., Shafi, S., Diaz-Arrastia, R. Ethnic Differences in Rehabilitation Placement and Outcome after TBI. J Head Trauma Rehabil (2): PMID Marquez de la Plata, C., Hart, T., Hammond, F., Frol, A., Hudak, A., Harper, C., O'Neil-Pirozzi, T., Whyte, J., Diaz-Arrastia, R. Impact of Age on Long-term Recovery from Traumatic Brain Injury. Arch Phys Med Rehabil. May (5): PMCID

6 8. Weiner, M., Vega, G., Diaz-Arrastia, R., Moore, C., Madden, C., Hudak, A., Lütjohann, D. Plasma 24S-hydroxycholesterol and other Oxysterols in Acute Closed Head Injury. Brain Inj (7): PMID Hudak, A., Warner, M., Marquez de la Plata, C., Moore, C., Harper, C., Diaz- Arrastia, R. Brain morphometry changes and depressive symptoms after traumatic brain injury. Psychiatry Research: Neuroimaging (3): PMID Hudak, A., Hynan, L, Harper, CR., Diaz-Arrastia, R. Association of depressive symptoms with functional outcome after traumatic brain injury. Accepted to J Head Trauma Rehabil. Epub ahead of print March 24, ABSTRACTS Frol, A., Hudak, A., Harper, C., Caesar, R., Marquez de la Plata, C., Carlile, M., Diaz-Arrastia, R. Postconcussion symptoms in traumatic brain injury at 6 months post injury. J Head Trauma Rehabil (5), (abstract). Hudak, A, Hynan L, Diaz-Arrastia, R. Correlation between Functional Status Examination and Glasgow Outcome Scale-Extended with the Beck Depression Inventory-II in Traumatic Brain Injury Patients. J Neurotrauma (8):A-17 (abstract). POSTER PRESENTATIONS Hudak, A, Hynan L, Diaz-Arrastia, R. Correlation between Functional Status Examination and Glasgow Outcome Scale-Extended with the Beck Depression Inventory-II in Traumatic Brain Injury Patients. Neurotrauma 2009: The Second Joint Symposium of the International and National Neurotrauma Societies, with AANS/CNS Section on Neurotrauma and Critical Care; Sept. 7-11, Hudak, A., Warner, M., Marquez de la Plata, C., Arenivas, A., Krishnan, K., Culver, C., Moore, C., Harper, C., Diaz-Arrastia, R. Imaging of Post-Traumatic Brain Injury Depression. Presented at the 2010 Greater Dallas Human Brain Imaging Retreat. Nov.4, 2010,. INVITED LECTURES Kaiser Foundation Rehabilitation Center 11th Annual Symposium, Rehabilitation Following Neurotrauma Oakland, California Title: Condition Management: Overview: Traumatic Brain Injury October 30, 2008

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