Curriculum vitae. -Supervisor of students clinical work and teaching at the Post-graduate course in Periodontology University of Padova:

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1 Curriculum vitae Maria Gabriella Grusovin Born in Novara, Italy, on the 25th of August 1964 Citizenship: Italian - Graduated in Dentistry at the University of Trieste, Italy, on the 27 of July 1988 with the highest mark (110/110 cum laude) - Specialty in Periodontology and Implants: The Institute for Postgraduate Dental Education in Jönköping, Sweden (01 September September 1996) -Supervisor of students clinical work and teaching at the Post-graduate course in Periodontology University of Padova: Senior Clinical Teaching Instructor Master course in Implantology: University of Manchester April 2007 Member of the Editorial Board of the European Journal of Oral Implants ( EJOI) and of the Rivista Italiana Stomatologia (RIS) - Awards Rotary Club Award: best graduated student of the faculty of Medicine University of Trieste Second author in the article, The Efficacy of Various Bone Augmentation Procedures for Dental Implants: A Cochrane Systematic Review of Randomized Controlled Clinical Trials published in Volume 21, Number 5, 2006 of the International Journal of Oral and Maxillofacial Implants (IJOMI) winner of the Academy of Osseointegration s William R. Laney Award Boston Private practice as general dentist since Practising implant dentistry since Clinical practice limited to implant dentistry, periodontal therapy and prosthetic rehabilitation since 1995 Referee for the Rivista Italiana di Stomatologia (R.I.S.); the European Journal of Oral Implantology (EJOI) Professional memberships 1) Association of Italian Dentists (AIO): member ; auditor ) National Association of Italian Dentists (ANDI): member from 1991 Provincial Cultural Secretary (Gorizia): Regional Cultural Secretary (Friuli Venezia Giulia): from 2004 Member of the National ANDI work- group on Clinical Guidelines development from 2005 National Cultural vice-secretary: from ) Scandinavian Periodontal Society: member ) Italian Society of Periodontology (SIdP): member from ) S.I.O. (Italian Society of Osseointegration): member from ) S.I.C.O.I. (Italian Society Oral Surgery and Implantology): member from

2 Teaching Experience - National and international seminars/courses as Speaker 1) Risk Markers for Periodontal disease: Jönköping, Sweden March ) Assessment of risk predictors in an Italian population: Jönköping, Sweden April ) Peri-implant diseases: JUST Course on Periodontology Jönköping, Sweden 2 February ) Guided tissue regeneration with bioresorbable membranes: Clinical course: Gorizia, Italy 15 March ) Periimplantitis: which diagnosis and treatment?: III Congress 3A Triveneto Udine, Italy October ) Periodontal problems and prevention: University for the third age, Gorizia, Italy ) The treatment angular bony defects: 1st Meeting Swedish post-graduates in Periodontology Rimini, Italy, 1 March ) The treatment of teeth with compromised furcations: 3th Meeting Swedish post-graduates in Periodontology Fermo, Italy, 14 March ) Periimplantitis: etiology and treatment: 4th Meeting Swedish post-graduates in Periodontology Alghero, Italy, 15 April ) Regeneration therapy in periodontology: indications and limits: 6 th Meeting Swedish postgraduates in Periodontology Gorizia, Italy 6-8 September ) Sharpening of periodontal instruments: Trieste, Italy 08 April 2000 and Udine, Italy, October ) Dental disease prevention during pregnancy and childhood: two lectures annually from 1999, Progetto Nascita, Gorizia, Italy 13) The hygienist and dental assistant role in periodontal therapy: Cenacolo Odontostomatologico triveneto, Associazione Italiana di Odontoiatria Generale, Trieste, Italy 7 April ) Diagnosis in Periodontology: SidP Course: 11 November 1999, 11 May 2000, 9 November 2000 Gorizia, Italy 23 March 2000 Monfalcone, Italy 15) Regeneration in periodontal therapy: indication and limits: Cenacolo Odontostomatologico Triveneto, Associazione Italiana di Odontoiatria Generale Padova 22 September ) Clinical guidelines: Italian experience and future perspectives: 6th International Congress on Dental Law and Ethics, Florence, Italy October ) Enamel matrix derivatives: from clinical experience to scientific evidence: Closed annual meeting of the Boston University Italian Alumni Rome, Italy 1 April ) Clinical guidelines: what they are and how they are made: Round table: Decontamination of oral cavity: from empirical approach to Italian guidelines Collegio dei Docenti Rome, Italy 7 April ) Enamel Matrix Derivative (Emdogain )for periodontal tissue regeneration: Florence, Italy, 12 May

3 20) Periimplantitis: which diagnosis and treatment? Post graduate course in Implantology Modena, Italy 23 June ) Chairman: Limits and expetations in implantology: from surgery to prostesis. XII Congresso triveneto Tricesimo, Italy October ) Periimplantitis; which diagnosis and treatment on an evidence based approach: Faenza Andi Congress 14 April ) Periimplantitis: which diagnosis and treatment? Post graduate course in Implantology Modena 04 May ) Periimplantitis: which diagnosis and treatment? ANDI Course Marina di Lepanto Monfalcone 19 May ) Discussion on alternative treatment of a tooth with questionable prognosis. Gradisca 08 November ) Periimplantitis: which diagnosis and treatment? Up-dating Course in Implantology Udine 10 November ) Periimplantitis: which diagnosis and treatment on an evidence based approach? IV Regional ANDI Congress Roma 24 November ) Periimplantitis: which diagnosis and treatment? The Dental Implant Seminar Series at the University of Manchester Manchester 14 December ) Therapeutic alternatives and related problems in the treatment of a compromised tooth. ANDI regional Congress Genova 05 April ) Discussion on alternative treatment of a tooth with questionable prognosis. Trieste 21May ) Periimplantitis: which diagnosis and treatment on an evidence based approach? Bolzano 14 June ) Gingival diseases and dental implants: general aspects and influence on the patient Cortina Hotel Mirafiori 04 August ) Discussion on alternative treatment of a tooth with questionable prognosis. Pordenone 24 September ) Tooth or Implant: which scientific evidence in treatment choice. Venezia 04 October ) Biological complication around implants: diagnosis, prevention and treatment based on an evidence based approach. Ancona 10 October ) Periimplantitis: which diagnosis and treatment on an evidence based approach? Rome 13 October ) Periimplantitis: which diagnosis and treatment? Post graduate course in Implantology Modena 08 November ) The evidence based Literature on replacement treatment: the correct use of the literature. Rome 15 November ) How to treat biological complication in Implant dentistry: diagnosis, prevention, treatment. Pordenone 13 December

4 40) Implantology: which are the treatments available with the new and the old techniques dentist can use. Gorizia 17 december ) Discussion on alternative treatment of a tooth with questionable prognosis. Pordenone 24 Febbraio ) The present scientific evidence in Implantology. Cortina ANDI congress ECM course 6 March ) Implants: are they better or worse than teeth? Risk factors, maintenance. Diagnosis and treatment of periimplant diseases. ECM course Ostuni 04 April ) Teeth or Implants: the choice! Clinics and scientific evidence. Motta di Livenza (TV) ECM course 12 May ) The management of perimplant soft tissue: clinics and scientific evidence. Treviso ANDI course. ECM course 27 May ) Teeth or Implant: which evidence in the therapeutic choice. Master course in Guided implant surgery. Padova 10 September ) Post-extractive implants: clinics and scientific evidence. Motta di Livenza (TV) ECM course 22 September ) The scientific evidence on the mini-invasive implant treatment. XII International Congress of Implant Therapy Verona 23September ) The foreseen mistake: in implantology Lombardia Regional Course. ECM course. Castello Visconteo, Somma Lombarda 17 October ) Peri-implant pathologies: diagnosis and treatment Lazio Regional Congress Expodental Forum ECM course Roma 17 October ) Lecture on clinical aspects of post extractive implants, sinus lift, immediate loading. Master course in Implantology Rome October ) Mini invasive implant surgery to simplify patient treatment Catania 23 January 2010 ECM course Andi 53) Presentation on Implant Maintenance: Consensus conference on Implant Maintenance and Treatment of Periimplantitis - Scottish Society of Implantology Glasgow 26 April ) Aesthetic in Dentistry and Implantology. Congress Aesthetic in Dentistry ECM course Bologna 17 April ) The GBR technique Rome S.Luigi Hospital Congress- Live conference with Argentina. Rome 15 May ) Implants in extraction sockets: scientific evidence and clinical practice. Pechin University School of Stomatology. Pechin 20 August

5 - Scientific direction and course organization: 1) Laser in dentistry: Palmanova, Italy 13 July ) Treatment plan in implant prosthesis: Gorizia, Italy 14 November ) Success in implant therapy: Palmanova, Italy 07 December ) Instruments and materials in the modern endodontic practice: Gorizia, Italy 03 July ) Electomiography in clinical dentistry: Gorizia, Italy 10 July ) Occlusion in fixed prosthesis: Gorizia, Italy 07 November ) Oral lesions in the dental practice: clinical cases: Gorizia, Italy, 1 December ) Prosthesis on implants - function and esthetics: Palmanova, Italy 5 December ) Digital photography: Gradisca, Italy 16 March ) The treatment of the patient with systemic pathologies, drugs prescription and treatment of emergency: Palmanova, Italy 17 September ) The success and failures in implant therapy - mistakes or complications?: Pordenone, Italy 26 November ) The periodontal compromised patient - implants or teeth?: Pordenone, Italy 28 January ) Member of the scientific commitee of the 58th Scientific National Congress ANDI Palermo, Italy 4-6 May ) A better quality in patient clinical treatment: sinergy between public and private care Regional Congress ANDI Friuli Venezia Giulia Gorizia 9-10 May ) Implants: everyday use and up to date scientific evidence: Pordenone 13 December ) The management of the private practice. Palmanova 12 December ) Member of the Scientific Committee Poster Award at our 14 th DENTSPLY Friadent World Symposium on March 19/20, 2010 in Barcelona Supervision of MSc theses Supervision: : Elli Jourabchian: Intervention for replacing missing teeth: Maintaining and recovering soft tissues health around dental implants Nigel Saynor: Marginal soft tissue changes and Aesthetic evaluation of Immediately placed and provisionalised single implants in post extraction sites: An audit of cases with three or more years follow up : Georgios Karatzopoulos: Intervention for replacing missing teeth: vertical bone augmentation techniques for dental implant treatment Minesh Talati: Interventions for replacing missing teeth: antibiotics at dental implant placement to prevent complications Co-supervision: Hubert Achille: : Interventions for replacing missing teeth: different times for loading dental implants : Peter George: Intervention for replacing missing teeth: Maintaining and recovering soft tissues health around dental implants 5

6 Lectures at Manchester University: How to present a case Clinical Photography: theory and hands-on Periimplantitis: diagnosis and treatment Maintenace around implants Case presentations and thesis presentations added lectures: Management of soft tissues around implants Soft tissues augmentation: hands on Post extractive implants added lectures: Management of Periodontal patients Management of complications around implants Research Experience - Associate researcher at the Institute of Dentistry, University of Turku, Finland: Published Articles 1) Grusovin MG: Fluoride: methabolism and toxicity. Dental Materials & Devices n. 4 April ) Grusovin MG: Salivary flow, ph and dental caries: an operative methodology. Odontostomatologia e Implantoprotesi n. 4 April ) R Di Lenarda, Grusovin MG: The effect of soft drinks with acid ph on the tooth enamel: electronic microscope observations" Dental Materials & Devices n. 1-2 January-February ) Grusovin MG: Caries prevention: the use of chewing-gum. Dental Materials & Devices n. 3 March ) Norderyd O, Hugoson A, Grusovin G. : Risk of severe periodontal disease in a Swedish adult population. A longitudinal study. J Clin Periodontol 1999;26: ) Cordioli G, Mortarino C, Chierico A, Grusovin MG, Majzoub Z: Comparison of 2 techniques of supepithelial connective tissue graft in the treatment of gingival recession. J Periodontol 2001; 72: ) Cordioli G, Mortarino C, Chierico A, Grusovin MG, Majzoub Z: Histology of connective tissue graft. A case report. J Periodontol 2001; 72: ) Esposito M, Grusovin MG, Coulthard P, Thomsen P, Worthington H: A 5-year follow-up comparative analysis of the efficacy of various osseointegrated dental implant systems. A systematic review of randomised controlled clinical trials. J Oral Maxillofac Implants 2005 ; 20: Reprinted in Italian in Implantologia 2006 ; 4 : ) Esposito M, Grusovin MG, Worthington HV, Coulthard P: Enamel matrix derivative (Emdogain ) for periodontal tissue regeneration in intrabony defects. The Cochrane Database of Systematic Reviews 2005 issue 4 10) Esposito M, Grusovin MG, Coulthard P, Worthington HV: Intervention for replacing missing teeth: bone augmentation techniqes for dental implant treatment. The Cochrane Database of Systematic Reviews 2005 issue 4 6

7 11) Esposito M, Grusovin MG, Coulthard P, Worthington HV: Intervention for replacing missing teeth: treatment of periimplantitis. The Cochrane Database of Systematic Reviews 2006 issue 5 13) Esposito M, Grusovin MG, Coulthard P, Worthington HV: The Efficacy of Various Bone Augmentation Procedures for Dental Implants. A Cochrane Systematic Review of Randomized Controlled Clinical Trials. J Oral Maxillofac Implants 2006; 21: reprinted in German Implantologie 2007; 15: 9-28 and winner of the William R. Laney Award by the American Academy of Osseointegration as best paper published in the International Journal of Oral and Maxillofacial Implants for the year ) Esposito M, Grusovin MG, Willing M, Coulthard P, Worthington HV: Intervention for replacing missing teeth: different times for loading dental implants. The Cochrane Database of Systematic reviews ) Esposito M, Grusovin MG, Worthington HV: Reproducibility of quantitative subjective evaluation of aesthetic changes in implant dentistry by patients and dentists. J Oral Maxillofac Implants submitted 16) Esposito M, Grusovin MG, Marghareit H, Coulthard P, Worthington HV: Intervention for replacing missing teeth: management of soft tissue for dental implants. The Cochrane Database of Systematic reviews 2007 issue 3 17) Esposito M, Grusovin MG, Martinis E, Coulthard P, Worthington HV: Intervention for replacing missing teeth: 1 vs 2 stage implant placement. The Cochrane Database of Systematic reviews 2007 issue 3 18) Esposito M, Grusovin MG, Coulthard P, Worthington HV: Which is the Most Effective way to Treat Perimplantitis: An Evidence-based Summary of a Cochrane Systematic Review Dental Tribune 2007 submitted 19) Esposito M, Grusovin MG, Willing M, Coulthard P, Worthington HV: The effectiveness of immediate, early, and conventional loading of dental implants. A Cochrane Systematic Review of Randomized Controlled Clinical Trials.J Oral Maxillofac Implants 2007 ; 22 : ) M. Esposito, L. Murray-Curtis, M.G. Grusovin, P. Coulthard, H.V. Worthington: Interventions for replacing missing teeth: different types of dental implants. Cochrane Systematic Review (UPDATE 3). The Cochrane Library 2007; 4 21) M. Esposito, M.G. Grusovin, S. Patel, H.V. Worthington, P. Coulthard: Interventions for replacing missing teeth: hyperbaric oxygen therapy for irradiated patients who require dental implants. Cochrane systematic review (UPDATE 1). The Cochrane Library 2008; 1 22) M.G. Grusovin, P. Coulthard, E. Jourabchian, H.V. Worthington, M. Esposito: Interventions for replacing missing teeth: maintaining healthy tissues around dental implants. Cochrane Systematic Review (UPDATE 2). The Cochrane Library 2008; 1 23) Grusovin MG, Coulthard P, Worthington HV, Esposito M: Maintaining and recovering soft tissue health around dental implant. A Cochrane Systematic Review of Randomized Controlled Clinical Trials. Europen Journal of Oral Implantology 2008; 1:

8 24) Coulthard P, Patel S, Grusovin MG, Worthington HV, Esposito M: Hyperbaric oxygen therapy for irradiated patients who require dental implants: A Cochrane Review. Europen Journal of Oral Implantology 2008 ;1: ) M. Esposito, M.G. Grusovin, S. Kwan, H.W. Worthington, P. Coulthard: Interventions for replacing missing teeth: bone augmentation techniques for dental implant treatment. Cochrane Systematic Review (UPDATE 2). The Cochrane Library 2008; 3 26) M. Esposito, M.G. Grusovin, M. Talati, P. Coulthard, R. Oliver, H.V. Worthington: Interventions for replacing missing teeth: antibiotics at dental implant placement to prevent complications. Cochrane Systematic Review (UPDATE 1). The Cochrane Library 2008; 3 27) Esposito M, Grusovin MG, Coulthard P, Worthington HV: Intervention for replacing missing teeth: treatment of periimplantitis. A Cochrane systematic review of clinical trials. Europen Journal of Oral Implantology 2008; 1: ) M. Esposito, M.G. Grusovin, P. Coulthard, R. Oliver, H.V. Worthington: The efficacy of antibiotic prophylaxis at placement of dental implants: a Cochrane systematic review of randomized controlled clinical trials. European Journal of Oral Implantology 2008; 1: ) M. Esposito, M.G. Grusovin; H. Achille, P. Coulthard, H.V. Worthington: Interventions for replacing missing teeth: different times for loading dental implants. Cochrane Systematic Review (UPDATE 3). The Cochrane Library 2008; 4 30) M. Esposito, M.G. Grusovin, P. Coulthard, H.V. Worthington: Different loading strategies of dental implants. A Cochrane systematic review of randomised controlled clinical trials. European Journal of Oral Implantology 2008; 1: ) Grusovin M.G., Esposito M.: The efficacy of enamel matrix derivative (Emdogain) for the treatment of deep infrabony periodontal defects: a placebo-controlled randomised clinical trial. European Journal of Oral Implantology 2009; 1: ) M. Esposito, M.G. Grusovin; Y.S. Chew, P. Coulthard, H.V. Worthington: Interventions for replacing missing teeth: 1- vs 2-stage implant placement. Cochrane Systematic Review (UPDATE 1). The Cochrane Library 2009; 3 33) M. Esposito, M.G. Grusovin, H. Worthington: Reproducibility of quantitative subjective evaluation of aesthetic changes in implant dentistry by patients and dentists. The International Journal of Oral and Maxillofacial Implants ) M. Esposito, M.G. Grusovin, P. Felice, G. Karatzopoulos, H.V. Worthington, P. Coulthard: Interventions for replacing missing teeth: horizontal and vertical bone augmentation techniques for dental implant treatment. Cochrane Systematic Review (UPDATE 3). The Cochrane Library 2009; 4 35) M. Esposito, M.G. Grusovin; Y.S. Chew, P. Coulthard, H.V. Worthington: One-stage versus 2- stage implant placement. A Cochrane Systematic Review of randomised controlled clinical trials. European Journal of Oral Implantology 2009; 2: ) M. Esposito, M.G. Grusovin, N. Papanikolaou, P. Coulthard, H.V. Worthington: Enamel matrix derivate (Emdogain) for periodontal tissue regeneration of intrabony defects. Cochrane Systematic Review (UPDATE 2). The Cochrane Library 2009; 4 8

9 37) M. Esposito, M.G. Grusovin, P. Felice, G. Karatzopoulos, H.V. Worthington, P. Coulthard: The efficacy of horizontal and vertical bone augmentation procedures for dental implants A Cochrane systematic review. European Journal of Oral Implantology 2009: 2: ) M. Esposito, M.G. Grusovin, N. Papanikolaou, P. Coulthard, H.V. Worthington: Enamel matrix derivate (Emdogain) for periodontal tissue regeneration of intrabony defects. A Cochrane systematic review. European Journal of Oral Implantology 2009: 2; ) M. Esposito, M.G. Grusovin, J. Rees, D. Karasoulos, P. Felice, R. Alissa, H.V. Worthington, P. Coulthard: Interventions for replacing missing teeth: augmentation procedures of the maxillary sinus. Cochrane Systematic Review. The Cochrane Library Mar 17;3 40) M. Esposito, M.G. Grusovin, J. Rees, D. Karasoulos, P. Felice, R. Alissa, H.V. Worthington, P. Coulthard: Effectiveness of sinus lift procedures for dental implant rehabilitation: a Cochrane systematic review. European Journal of Oral Implantology. 2010: 3(1): ) M. Esposito, M.G. Grusovin, E.Tzanetea, A. Piattelli, H.V. Worthington: Intervention for replacing missing teeth: treatment of perimplantitis. Cochrane Database Syst Rev Jun 16;6 42) M. Esposito, H.V. Worthington, V.Loli, P. Coulthard, M.G. Grusovin: Intervention for replacing missing teeth: antibiotics at dental implant placement to prevent complications. Cochrane Database Syst Rev Jul 7;7 43) M. Esposito, H.V. Worthington, V.Loli, P. Coulthard, M.G. Grusovin:Does antibiotic prophylaxis at implant placement decrease early implant failures? A Cochrane systematic review. Eur J Oral Implantol Summer;3(2): In Press: 44) M.G. Grusovin, P. Coulthard, P. George, H.V. Worthington, M. Esposito: Interventions for replacing missing teeth: maintaining healthy tissues around dental implants. Cochrane Systematic Review (UPDATE 3). The Cochrane Library 9

10 Book Chapters: 1) M.G. Grusovin : The function of Scientific Literature in answering clinical questions. In Ferro S., Grusovin M.G., Scarpelli M. The Clinical Guidelines ANDI ) M. Esposito, M.G. Grusovin, P. Coulthard and H. Worthington: What have we learned from randomized controlled clinical trials on oral implants? In Osseointegration and Dental Implants, A. Jokstad ed. Blackwell Wiley-Blackwell, 2009 pages ) M. Esposito, M.G. Grusovin, P. Felice, G. Karatzopoulos, H.V. Worthington, P. Coulthard: The efficacy of horizontal and vertical bone augmentation procedures for dental implants A Cochrane systematic review. In Evidence-Based Practice Toward Optimizing Clinical Outcomes, F. Chiappelli ed. Springer-Verlag, 2010, pp Poster Presentations/Abstracts: 1) The Necrotizing Ulcerative Gingivitis Jönköping, Specialists day Spring ) Grusovin MG, Pienihakkinen K, Tiekso J, Scheinin A: Assessment of risk predictors for periodontal disease progression in Italian subjects: one-year and three-year observation Europerio 2 Florence, Italy May ) Varrela TM, Ikola S, Grusovin MG, Vályi P, Vallittu P: Longevity of Fibre Reinforced Composite Periodontal Splints. IADR 2004 abstract 4) M. Esposito, M.G. Grusovin, H. Maghaireh, P. Coulthard, H.V. Worthington: Management of soft tissues for dental implants (systematic review). EAO (European Association for Osseointegration) 17 th Annual Scientific Meeting, September 18-20, 2008, Warsaw, Poland - Ongoing research projects: 1) Grusovin MG, Worthington HV, Esposito M: Evaluation of aesthetic changes in implant dentistry (research protocol at planning stage) 2) Internal versus external connection of dental implants. A multicentre pragmatic randomized controlled clinical trial: clinical center 3) Evaluation of a novel nanostructured calcium-incorporated titanium surface (Xpeed) for the treatment of maxillary edentulism: a pilot multicenter randomised controlled clinical trial clinical center 4) Immediate versus conventional loading of dental implants in partially edentulous patients. A multicentre randomized controlled clinical trial clinical center 5) The effectiveness of a bone substitute in the treatment of infrabony defect - a multicenter pragmatic randomized clinical trial clinical center 6) The effectiveness of adjunctive light activated disinfection in the treatment of perimplantitis - a multicenter pragmatic randomised clinical trial clinical center 7) Grusovin M.G., Esposito M. : Roll vs graft technique for augmenting soft tissue at implant sites: a randomized controlled clinical trial 10

11 Internships and residencies The Hebrew University - Haddasach School of Dental Medicine - Department of Hospital Dentistry, Oral Surgery- Jerusalem - Israel 28/07/1987 to 14/08/1987 University of Trieste - Dental Clinic - Trieste - Italy - 09/12/1988 to 31/12/1990 University of Turku - Institute of Dentistry - Turku - Finland 20/08/1989 to 01/09/1989 The Institute for Postgraduate Dental Education - Department of Periodontology - Jönköping Sweden - 20/08/1990 to 31/08/1990 University of Turku - Institute of Dentistry - Turku - Finland - 13/08/1991 to 31/08/1991 University of Turku - Institute of Dentistry - Turku - Finland - 18/08/1993 to 05/09/