Quality and Risk Management in the IVF Laboratory
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1 Quality and Risk Management in the IVF Laboratory Second Edition
2
3 Quality and Risk Management in the IVF Laboratory Second Edition Sharon T. Mortimer, PhD Director, Oozoa Biomedical Inc. West Vancouver, BC, Canada David Mortimer, PhD President, Oozoa Biomedical Inc. West Vancouver, BC, Canada
4 University Printing House, Cambridge CB2 8BS, United Kingdom Cambridge University Press is part of the University of Cambridge. It furthers the University's mission by disseminating knowledge in the pursuit of education, learning and research at the highest international levels of excellence. Information on this title: / Cambridge University Press (2008) 2015 This publication is in copyright. Subject to statutory exception and to the provisions of relevant collective licensing agreements, no reproduction of any part may take place without the written permission of Cambridge University Press. First published 2005 Second edition 2015 Printed in the United Kingdom by Clays, St Ives plc A catalog record for this publication is available from the British Library Library of Congress Cataloging in Publication data Mortimer, David, 1953, author. Quality and risk management in the IVF laboratory / Sharon T. Mortimer, David Mortimer. Second edition. p. ; cm. Authors' names reversed on the first edition. ISBN (Paperback) I. Mortimer, Sharon T. (Sharon Tracey), 1961, author. II. Title. [DNLM: 1. Fertilization in Vitro standards. 2. Clinical Laboratory Techniques standards. 3. Quality Control. 4. Risk Management methods. WQ 208] RG dc ISBN Paperback Cambridge University Press has no responsibility for the persistence or accuracy of URLs for external or third-party internet websites referred to in this publication, and does not guarantee that any content on such websites is, or will remain, accurate or appropriate.... Every effort has been made in preparing this book to provide accurate and up-to-date information which is in accord with accepted standards and practice at the time of publication. Although case histories are drawn from actual cases, every effort has been made to disguise the identities of the individuals involved. Nevertheless, the authors, editors and publishers can make no warranties that the information contained herein is totally free from error, not least because clinical standards are constantly changing through research and regulation. The authors, editors and publishers therefore disclaim all liability for direct or consequential damages resulting from the use of material contained in this book. Readers are strongly advised to pay careful attention to information provided by the manufacturer of any drugs or equipment that they plan to use.
5 Contents 1 Introduction 1 2 Regulation, licensing, and accreditation 6 3 Quality and quality management 16 4 What is risk? 39 5 Process and systems 49 6 Making it work 71 7 Quality and risk management tools What's gone wrong?: troubleshooting Risk management: being proactive How are we doing?: benchmarking Specifying systems Human resources: finding (and keeping) the right staff Illustrative example of a wellcontrolled laboratory Is the well-run lab enough?: quality and risk management in the IVF clinic 213 References 223 Index 229 v
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