Prof. Dr. Amjad Al-Niaimi

Transcription

1 Curriculum Vitae Prof. Dr. Amjad Al-Niaimi MD,D.M.R.T, FRCR Dutch Certificate in Radiotherapy - 1 -

2 Contents Contents... 2 Personal Details... 3 Professional Details... 4 Positions held in Clinical Oncology... 5 Private Practice Experience Positions held in Medicine and Surgery Teaching Experience Management and Organisations Publications Unpublished scientific papers delivered at various national medical conferences (Oral Presentations)23 Unpublished scientific papers delivered by oral presentation at various international medical conferences Invitations Seminars organised by me in Iraq Awards Recent meetings and conferences attended (CME & CPD) Most recent research experience in Clinical Trials References

3 Personal Details Name: Amjad Al-Niaimi Address: 6 Chatsworth Park Avenue Stoke on Trent ST4 4TY Telephone Number: Mobile Number: Address: a.alniaimi41@gmail.com As.niami@hotmail.com Date of Birth: 22 nd December Nationality: Iraqi/British Place of Birth: Duhok, Iraq. Marital Status: Married. Family: Two sons, two daughters. Hobbies: General reading, especially biography, writing poems, listening to classical music, and travelling

4 Professional Details GMC registration number: Full registration as a Medical Practitioner with Specialist Registration. Undergraduate Medical School: MD Medicine (1 st degree honour) June 1967 Second state Moscow Medical Institute, Moscow University. MB, Ch.B February 1968 College of Medicine, Baghdad University. Postgraduate D.M.R.T (Diploma in Medical Radiotherapy) April 1977 Royal College of Surgeons and Royal College of Physicians, London F.R.C.R (Fellowship of the Royal College of Radiologists) in Clinical Oncology October 1978 Accreditation in Clinical Oncology from the Royal College of Radiologists November 1985 Certificate from the Specialist Registration Committee of the Royal Dutch Medical Association January

5 Positions held in Clinical Oncology February December 2017 Locum cancer June2014-July2015 Locum Consultant clinical oncologist University hospital of North Midlands Treating lung, breast, lower gastro-intestinal and urology consultant clinical oncologist Inverness, Scotland Treating breast and lung November 2013 June 2014 Locum Consultant Clinical Oncologist Aberdeen Royal Infirmary Treating Breast and Lung cancer June 2013 November 2013 Locum Consultant Clinical Oncologist Mount Vernon Hospital King Edward hospital Windsor Hertfordshire Hospital ST Albans Treating breast Cancer November 2003 to retirement In 2013 Consultant Clinical Oncologist. University Hospital of North Staffordshire. Stoke on Trent. UK. Summary Lead on lung cancer and second lead on breast cancer at both University Hospital and mid-stafford General Hospital, Stafford

6 November 2002 October 2003: Locum Consultant Clinical Oncologist University Hospital of North Staffordshire. Stoke on Trent. UK. Lead on lung, breast, CNS. and upper-g.i. cancers. May 2001 November 2002: Consultant Clinical Oncologist. Department of Radiotherapy. Amsterdam Teaching Hospital, Amsterdam University, Amsterdam. The Netherlands. This is a well known department in the Netherlands. Majority of work done in conformal therapy. Performed brachytherapy in head, neck, breast and prostrate cancers. One of the few centres using hyperthermia in various tumour sites in particular recurrent breast cancer. Participated in weekly M.D.T. meetings in breast, lung and urological cancers. Main areas of interest: Breast, lung, C.N.S. and gynaecological cancers. May 2000 April 2001: Consultant Clinical Oncologist. Institute of Radiotherapy. Arnhem. The Netherlands. The institute is well equipped with CT scan planning

7 Responsible for treating over 300 patients. Participation in weekly M.D.T. meetings on breast cancer and general oncology. Main areas of interest: Breast, lung, C.N.S. and urological cancers. November 1999 April 2000: Consultant Clinical Oncologist. Department of Radiotherapy. Alkmaar Medical Centre. The Netherlands. Majority of work done in conformal therapy. Participation in weekly M.D.T. meetings in general oncology. Participation in monthly evening meetings discussing recent advances in different cancers as well as journal club and audits. Main areas of interest: Breast, lung, C.N.S, urological, gynaecological and skin cancers. October 1998 October 1999: Consultant Clinical Oncologist. Radiotherapy Department, Delft. The Netherlands. Responsible for treating 275 new cancer patients. Performed weekly joint breast clinic. Participation in weekly M.D.T. meetings. Participation in weekly meetings of the integral cancer centre in the region. Work mainly confined to: Breast, lung, urological and gastrointestinal cancers

8 October 1997 September 1998: Consultant Radiotherapist. Department of Clinical Oncology, Leiden Teaching Hospital. The Netherlands. Responsible for treating 200 new cancer patients. Participated in all scientific activities of the department, the teaching Hospital and integral cancer centre in the region. Participated in most conferences, symposia and scientific meetings organised by the Dutch Society of Clinical Oncology. Work mainly confined to: Breast, lung, C.N.S., urological, head and neck cancers

9 February 1992 December 1994: Professor in Clinical Oncology. College of Medicine. Baghdad University. Senior Consultant Clinical Oncologist. Institute of Radiotherapy and Nuclear Medicine. Baghdad. Head of the Department of Clinical Oncology. College of Medicine. Baghdad University. Head of Chemotherapy Unit. Baghdad Medical City. January 1986 January 1992: Assistant Professor in Clinical Oncology. College of Medicine. Baghdad University. Senior Consultant Clinical Oncologist. Institute of Radiotherapy and Nuclear Medicine. Baghdad University. Head of Chemotherapy Unit. Baghdad Medical City. April 1979 December 1985: Senior lecturer in Clinical Oncology. College of Medicine. Baghdad University

10 Consultant Clinical Oncologist. Institute of Radiotherapy and Nuclear Medicine. Baghdad. Largest oncology centre in Iraq, treating 5500 new cancer patients annually. Worked with five consultants, six specialist-training registrars and three S.H.O. s in the care of 90 inpatients. Responsible for the treatment of 1200 new cancer patients. Responsibilities included teaching of fifth-year medical students as well as the supervision of postgraduate students specialising in radiotherapy. Common cancers treated: Breast, lung, head and neck, lymphomas, paediatric tumours, bladder, gynaecological and thyroid cancers. May 1976 February 1979: Registrar in Clinical Oncology. Christie Hospital and Holt Radium Institute. Manchester. Took more responsibilities in prescribing and giving chemotherapy to mainly lymphomas and breast cancer patients. Planning of various radiotherapy techniques. Performed independently weekly new patient, follow-up and peripheral clinics. Responsible for weekly intracavity insertion for cervical cancers. Attended all scientific activities, including: Meetings, journal club and various courses organised by the North-West Health Authority as part of the teaching programme for the fellowship. August 1973 April 1976: Senior House Officer in Clinical Oncology

11 Christie Hospital and Holt Radium Institute. Manchester. Institute treating 5500 new patients. Actively involved in everyday work, rotating every three months with different working teams consisting of teams of two consultants with different specialities. These included: Head and neck, gynaecological, breast, paediatric and chemotherapy teams. Participated in the care of inpatients, performing various procedures, chemotherapy administration, weekly outpatients clinics, radiotherapy planning, weekly intracavity insertion of radium for cervical cancers. October 1970 July 1973: Registrar in Radiotherapy. Radiotherapy Department. Mosul Medical College. Mosul University. Mosul. Iraq. Active participation in establishment and the daily work of the department. 650 patients treated in the first year, increasing to 1200 new patients thereafter. Responsibilities included teaching of fifth-year medical students as well as the supervision of postgraduate students specialising on radiotherapy. Most common cancers treated were: lung, head and neck, lymphomas, breast, thyroid and skin

12 Private Practice Experience 2004 continue Staffordshire Nuffield Hospital Clayton Road Newcastle under -Lyme Stoke on Trent ST5 4DB United Kingdom Capio Rowley Hall Hospital Rowley Park Stafford, ST17 9AQ United Kingdom January 1982 December 1995: Clinical Oncology. Private Clinical Oncology Clinic. Baghdad. Clinic operated five days per week between five and ten PM for around 40 new and follow up, radiotherapy and chemotherapy patients. Admitting patients at various private hospitals in Baghdad. Administration of chemotherapy to patients by experienced nursing staff under my direct supervision in the clinic as well as in various private hospitals in Baghdad June 1979 December 1981: Clinical Oncology

13 Specialist Clinic. College of Medicine. Baghdad University. Clinic sponsored by Baghdad University in the field of clinical oncology three days per week. November 1970 July 1973: General Practitioner. Mosul. Iraq. Clinic in general medicine and paediatrics five days per week. January 1969 September 1970: General Practitioner. Habbaniya Military Hospital. Iraq. Clinic in general medicine and paediatrics five days per week

14 Positions held in Medicine and Surgery October 1968 September 1970: Medical Officer in general surgery, accident and emergency and general medicine during compulsory military service at Habbaniya military hospital, Iraq All patients were military service personnel. October 1967 September 1968: Resident house officer in general medicine, surgery, gynaecology and paediatrics as intern at the Mosul Teaching Hospital, Mosul, Iraq. University Teaching Hospital served a population of one million with 400 beds. Actively engaged in everyday work, including minor surgeries

15 Teaching Experience Undergraduate: 2003 Present: Keele University Stoke On Trent North Staffordshire United Kingdom Teaching 4 th year medical students about lung cancer and breast cancer : College of Medicine, Baghdad University. Teaching course of clinical oncology and nuclear medicine to the 5 th year medical students. The course consists of ten lectures and two weeks of practical attendance at the radiotherapy institute and clinical oncology unit at the medical city teaching hospital : Salahedeen Medical School. Arbil University. Kurdistan Province. Iraq. Visiting senior lecturer teaching a comprehensive course of clinical oncology and nuclear medicine to the 5 th year medical students

16 : School of Radiography. Bahgdad. Teaching principles of radiotherapy to therapeutic radiographers : Basra Medical School. Basra University. Basra. Iraq. Teaching a comprehensive course of clinical oncology and nuclear medicine to the 5 th year medical students : Nursing School. Mosul. Iraq. Teaching general medicine

17 Postgraduate: : Baghdad Medical teaching Hospital (Medical City). College of Medicine. Baghdad University. Baghdad. Iraq. Teaching the course of clinical oncology to the postgraduate students for the degrees of diploma, Arab board and Iraqi board in the following specialities: General surgery. General medicine. Paediatrics. Gynaecology. Chest surgery. Diagnostic radiology. Oncological pathology. Teaching was delivered in the form of lectures, tutorials, practical sessions, symposia and topic discussions : Diploma in Medical Radiotherapy. Medical College. Baghdad University. Baghdad. Iraq. I introduced a comprehensive postgraduate teaching (Clinical and practical) study of two years duration for specialist registrars in clinical oncology for the degree of diploma in radiotherapy (Similar to the D.M.R.T. in the UK). This has been approved by Irish Medical authorities

18 Until 1995, thirteen postgraduate students had obtained their diploma and now they constitute 70% of working radiotherapists in Iraq : Medical College. Baghdad University. Baghdad. Iraq. Co-sponsor for the degree on Master in Sciences (M.Sc) in the following specialities: Pathology. Community Medicine. Orthopaedics. Biochemistry. Dozens of postgraduate medical doctors obtained their M.Sc. in the above fields related to clinical oncology : Dental College. Baghdad University. Baghdad. Iraq. Postgraduate degree in Oral Medicine in the field of clinical oncology (Head and Neck cancer)

19 Management and Organisations All the following management, organisation and activities were during my work in Iraq. Head of section of clinical oncology ( ) Department of Surgery College of Medicine Baghdad University Head of Chemotherapy Unit ( ) Medical City Teaching Hospital Baghdad Instigating Member of the Iraqi Cancer Board, headed by the Minister of Health, representing the Ministry of Higher Education and Scientific Research since its establishment in 1984 until The board is the highest national body responsible for the planning and organisation of all cancer services, research and development in Iraq. Medical advisor to the Iraqi Ministry of Health on radiation protection from 1980 to Head of the Medical Committee for radiation workers in Iraq from 1980 to Instigating member and vice-president of the Iraqi Radiological Society since its establishment in 1984 until Member of the board of the Iraqi Cancer Society from 1980 to Head of the Lung Cancer Network Group ( ) Vice-chairman of the Breast Cancer Network Group ( )

20 Vice-chairman of the Lymphoma Network Group ( ) Member of the Dutch Society of Radiation Oncologists (N.V.R.O.) in Holland. Member of ESTRO (European Society of Therapeutic Radiotherapy and Oncology)

21 Publications Embryonal Rhabdomyosarcoma (Sarcoma Botryoides) in childhood. J. Fac. Med Baghdad Vol. 25 No Gastro-intestinal cancer in Iraq. Published in the proceedings of the 2 nd international conference on cancer prevention in Kuwait, Clinico-pathological review of cancer of the bronchus. J. Fac. Med Baghdad Vol. 27 No Estimation of serum aluminium level in normal and cancer patients. J. Fac. Med Baghdad Vol. 27 No Radiotherapy management of superior sulcus tumour. J. Fac. Med Baghdad Vol. 28 No Combination chemotherapy in the management of advanced gastro-intestinal cancer. J. Fac. Med Baghdad Vol. 29 No Primary Hepato-cellular carcinoma in Iraq. Tropical gastroenterology Vol. 8 No. 4. Oct The diagnostic value of Ca 19.9 tumour marker antigen determination in patients with gastro-intestinal cancer. J. Fac. Med Baghdad Vol. 30 No Influence of surgery and chemotherapy on cell mediated immune response in breast cancer patients. J. Biol. Sci. Res. Vol. 20. No Serum levels of Ca 15.3 in patients with breast cancer

22 J. Fac. Med Baghdad Vol. 32 No * Multiple tumour markers in patients with breast cancer. J. Fac. Med Baghdad Vol. 31 No * Carcinoma of the gall-bladder in Iraq. J. Fac. Med Baghdad Vol. 32 No Carcinoma of the nasopharynx, analysis of 50 patients. J. Fac. Med Baghdad Vol. 34 No ** Breast cancer in Iraq, analysis of 400 patients. Accepted for publication, J. Fac. Med * Presented at the international symposium on tumour markers, Taiwan, 1986, as posters. ** Presented at the first Franco- Arab conference on cancer, Paris, Palmar-Plantar erythrodysesthesia secondary to docetaxel chemotherapt: a case report, journal of medical case report

23 Unpublished scientific papers delivered at various national medical conferences (Oral Presentations) Lung cancer in Iraq. The magnitude of the problem and analysis of 344 patients. Arbil, Bone tumours in children. Analysis of 30 patients. Baghdad, Chemotherapy in Head and Neck cancer, personal experience. Mosul, Childhood CNS tumours. Analysis of 41 patients. Baghdad, Liver involvement in malignancy. Baghdad, (Delivered at the international symposium on liver diseases held in Baghdad). Chemotherapy of childhood solid tumours. Baghdad, Chemotherapy in ovarian cancer. Analysis of 70 patients. Baghdad, The place of adjuvant chemotherapy in early breast cancer. Baghdad, Bladder cancer in Iraq. Analysis of 200 patients. Baghdad, Extranodal Non Hodgkin s lymphomas. Analysis of 30 patients. Baghdad, Presentation and management of thyroid cancer in Iraq. Analysis of 80 patients. Baghdad, Hodgkin s disease in Iraq. Analysis of 70 patients treated over the years Baghdad,

24 Kaposi sarcoma in Iraq. Study of 21 patients. Baghdad,

25 Unpublished scientific papers delivered by oral presentation at various International Medical Conferences Neo-Adjuvant Chemotherapy in Hypopharyngeal Cancer. Analysis of 30 patients 6th International Conference of Bronchology & Oesophagology Japan, Carcinoma of the Larynx in Iraq. Analysis of 200 patients. 5th International Conference of Bronchology & Oesophagology Rio de Janiero, Brazil, Rio de Janiero Non-Hodgkin s lymphoma in Iraq. Analysis of 100 patients. Arab medical conference Algiers 1985 Combination Chemotherapy of VCR + ADR + CYCL + MTX in non Small-cell Lung Cancer

26 4th International Conference of Bronchology & Oesophagology Canada, Carcinoma of the Stomach in Iraq. Analysis of 100 patients. Second International Conference on Cancer prevention Kuwait, 1984 Abdominal Non-Hodgkin s Lymphoma in Iraq Analysis of 50 Patients. Mediterranean Conference on Lymphoma Greece, The Saloneek Primary Lymphoma of Small intestine (Mediterranean lymphoma) Analysis of 35 patients. Mediterranean Conference on Lymphoma Greece, The Saloneek Chemotherapy of Non Small-Cell Lung Cancer. Arab Medical Conference Libya, Tripoli Chemotherapy of Gastro- Intestinal Cancer. Arab Medical Conference Jordan, Amman

27 Chemotherapy of Small-Cell Lung Cancer. Arab Medical Conference Jordan, Amman

28 Invitations First Franco-Arab cancer conference. Founding member of the first Franco-Arab cancer conference, Paris, Opened by President Mitterand and sponsored by Jacques Chirac, then Mayor of Paris. International Conference in Lymphoma, Lugano, Switzerland, By invitation from the Saudi Government, I visited King Faisal Cancer Centre, representing Baghdad University Saudi Arabia, Riad 1983 By invitation from Cancer Centres in the USA, I had the opportunity in 1982 to visit each of the following Cancer Centres for two months: o o o o o o o o Georgetown Hospital, Washington DC. George Washington Hospital, Washington DC. Howard University, Washington DC. Walter Reed Army Medical Centre, near Washington. National Cancer Institute, Washington DC. Sloan Katering Hospital, New York. Massachusetts Cancer Hospitals, Boston. Stanford University, California

29 Seminars organised by me in Iraq. Pain relief in Cancer patients 1991 Psycho-Social aspects of Cancer 1990 Lung Cancer in Iraq Bladder Cancer in Iraq Head and Neck Cancer in Iraq Late Breast Cancer 1987 Burkitt s Lymphoma Early Breast Cancer Tumour Markers in Clinical Oncology The importance of Cytology in Clinical Oncology The multimodality approach in Cancer Management Cancer Screening and means of Cancer Prevention Cancer in Iraq, the magnitude of the problem and the need for cancer education

30 Awards Merit Certificate for Hospital Doctor awards 2005 for the Oncology Team of the Year in the United Kingdom for the Management of Lung Cancer. 16 awards by various organisations, ministries and colleges in Iraq

31 Other Activities During my work in the Netherlands between 1997 and 2002, I attended many national courses, seminars, conferences and symposia in various topics of radiotherapy, chemotherapy and new developments in the diagnosis of cancer and conformal therapy planning. In addition, I participated in the scientific meetings organised by the Dutch society of clinical oncology. Lecturing in more than 15 Conferences, Seminars and Symposia organized by various Medical Colleges, Societies and Hospitals in Iraq by invitation as invited speaker. Actively participated at the weekly Cancer Meetings at the Medical City Teaching Hospital, Iraq, Baghdad Chaired the Weekly Cancer Meeting at the Institute of Radiotherapy and Nuclear Medicine Iraq,Baghdad ( ). Invited Speaker on Lymphoma, AlKufa Medical College Iraq, Alkufa 1989 Invited Speaker on Lung cancer, Erbil Medical College, Iraqi Kurdistan Province, Iraq, Erbil 1988 Invited Speaker (keynote lecture) on Breast Cancer, Mosul Medical College, Iraq, Mosul 1986 Invited Speaker on Head and Neck Cancer to the Medical staff, College of Dentistry, Baghdad University, Lecturing on Mediterranean Lymphoma in Iraq to the Department of Radiotherapy, Georgetown Hospital, Washington Washington DC, Chaired many sessions at various Medical Conferences organised by Medical Colleges, Medical Societies and the Iraqi Cancer Society

32 Invited Speaker on Lung Cancer, Iraqi Medical Society for Chest Diseases Baghdad 1980 Invited Speaker on the Biology of Cancer to the Department of Biology, College of Sciences, Baghdad University, 1980 Media education about various aspects of cancer through newspapers, journals, radio and TV. Programmes. Publishing one book in Arabic about cancer for the general public

33 Recent meetings and conferences attended (CME & CPD) Cambridge course on Intensity modulated and image guided radiotherapy November 2015 PET CT in oncology : an update for MDT users October 2015, Leeds Statutory and Mandatory Training University Hospital of North Staffordshire July 2015 Radiotherapy Planning Review meeting University hospital of north Staffordshire June 2015 Good clinical practice ( GCP) Refresher A practical guide to ethical and scientific quality standards in clinical research July 2015 ALS Profile Training. Manual Handling. Fire Training. April GCP Training September 2012 Fourth Asian Pacific Conference Perspectives in Lung Cancer August

34 Introduction to ICH/GCP training 1 st March 2010 National Advanced Communication Skills Training( ACST) 3 day National ACST Course February 2010 British Thoracic Oncology Group Conference Dublin, Ireland January 2010 FORTIS-M, Investigator Meeting Oral TALACTOFERRIN as a third line treatment in NSCLC November 2009 Core Member of Breast Cancer Meeting Stafford General Hospital October 2009 IRESSA Launch Meeting September 2009 The Practical Management of Breast Cancer One day meeting July 2009 London One day meeting on SUPREMO trial in Breast Cancer Wythenshaw Hospital, Manchester June

35 44 Th American Society of Clinical Oncology(ASCO )Meeting CHICAGO USA June 2008 National Cancer Peer Review West Zone United Kingdom January th Annual San Antonio Breast Cancer Symposium San Antonio, Texas U. S.A December 2007 BEATRICE International Investigator Meeting Geneva, Switzerland October2007 European Society For Medical Oncology ESMO Conference Lugano Lugano, Switzerland October2007 The Herceptin Expert Forum London, United kingdom July

36 43 rd Annual Meeting of the American Society of Clinical Oncology (ASCO) CHICAGO, USA June 2007 The National Cancer Peer Review Reviewer Training Programme June 2007 United Kingdom The 5 th Annual British Thoracic Oncology Group Meeting Dublin, Ireland January 2007 Cancer Research UK Clinical Trials Unit 6 th National Breast Trials Meeting International Convention Centre Birmingham November 2006 IMRT Tomo Therapy& PET CT Cancer Management in the 21 st Century Royal College of Surgeons London September st ESMO Congress Istanbul, Turkey September-October th European Conference Perspectives in Lung Cancer

37 Athens, Greece September 2006 Interactive Lung Cancer Conference Lisbon, Portugal May th European Conference. Perspectives in Lung Cancer Conference. Amsterdam, the Netherlands. December th Annual National Lung Cancer and Mesothelioma Conference. National motorcycle museum, Birmingham. October Medical Management Conference, 2 day Conference. North Staffordshire Hospital. September th World Conference on Lung Cancer. Barcelona, Spain. July European Society for Medical Oncology. ESMO Scientific & Educational Conference. Budapest, Hungary. June ALS Profile Training

38 Manual Handling. Fire Training. February Perspectives in Lung Cancer. Berlin, Germany. 19 th 20 th November European Society of Medical Oncologists Annual Meeting. Vienna, Austria. 3 rd November 2004 New Directions in Breast Cancer. Crabwall Manor, Chester. 19 th October Curative Approaches in NSCLC. Belfry Hotel, Birmingham. 7 th October Bondronat Meeting in Jersey sponsored by Lilly. 25 th September 2004 Clinical Trial Training. Medical Institute, Stoke-on-Trent. 22 nd September Central England Lung Cancer Leads meeting. Coventry. July

39 Audit Meeting on Lung Cancer. Shrewsbury. 9 th June Practical Management of NSCLC. London. 28 th April The financial Delivery of the National Cancer Plan. House of Commons, London. 27 th April British Thoracic Oncology Group Meeting. Dublin, Ireland. January 2004 PET Seminar, Keele University, Stoke on Trent December th World Conference on Lung Cancer Vancouver, Canada August 2003 Appraisal Training, Stoke on Trent 18 th June Lung Cancer Meeting, London 8 th April

40 31 st March 2003 Breast Cancer Meeting, Dublin, Ireland March 2003 Lung Cancer Meeting, Birmingham, U.K 31 st March 2003 Thoracic Oncology Meeting Leicester, U.K February th National Lung Cancer Symposium Amsterdam, The Netherlands December

41 Most recent research experience in Clinical Trials PERSEPHONE TRIAL Duration of Trstuzimab with chemotherapy study, 6 months versus 12 months. FRAGMATIC TRIAL The use of low molecular chain heparin ( Deltaparin) in the management of locally Advanced or Metastatic Lung Cancer beside the Chemotherapy. IMPORT LOW Intensity modulated and Partial Organ Radiotherapy Randomised Trial Testing Intensity Modulated and Partial Organ Radiotherapy following Breast Conserving Surgery for Early Breast Cancer MRC SUPREMO TRIAL Selective Use of Postoperative Radiotherapy after Mastectomy TACT 2 Trial of Accelerated Adjuvant Chemotherapy with Capecitabine in Early Breast Cancer SOCCAR March 06 A randomised phase III trial of sequential chemotherapy followed by radical radiotherapy versus concurrent chemotherapy radiotherapy followed by chemotherapy in patients with inoperable stage 3 NSCLC and good performance status. TRANSHERA March 05 A randomised, three arm, multi-centre study comparing one year and two years of Herceptin versus no Herceptin in women with HER2 positive primary breast cancer who have completed adjuvant chemotherapy (HERA). FAST October

42 A prospective randomised Clinical Trial testing 5.7 GY and 6 Gy fractions of whole breast radiotherapy in terms of late normal tissue responses and tumour control in women prescribed whole breast RT after local excision of early Breast Cancer. AZURE April 04 A randomised phase III controlled study to determine whether adjuvant Zoledronic Acid reduces recurrence in patients with high-risk localised breast cancer. STUDY 14 March 04 A phase II/III randomised, double blind, placebo controlled trial of Gemcitabine/Carboplatin with or without Thalidomide in advanced non-small cell lung cancer. GELCAPS May 03 Principal Investigator The sample group will be all patients diagnosed with lung cancer, whether the patient smokes or not. Also the partner of the patient with lung cancer (not adenocarcinoma) is eligible to enter. BRAVE August 03 An open Label, Randomised Two-arm Study, to investigate the impact of Epoetin Beta T Treatment on Survival, Quality of life, outcome of Antineoplastic Therapy and anaemia in patients with Metastatic Breast Cancer. POSH A Prospective study of the outcomes of treatment in sporadic versus Hereditary Breast Cancer. A Blood sample study. August 2003 TACT BLOOD STUDY Retrospective and prospective collection of blood samples for DNA analysis in patients with early Breast Cancer. March 2003 HERA An international study of randomised three-arm multi-centre comparison of 1 year and 2 years of Herceptin versus no Herceptin in women with HER2 positive primary Breast Cancer who have completed adjuvant chemotherapy

43 May 2002 TEAM A national study of open label, randomised comparative trial of 5 years adjuvant Exemestane treatment versus 5 years adjuvant Tamoxifen in postmenopausal women with early breast cancer. May 2002 MESO-1 A national randomised feasibility study of active symptom control with or without chemotherapy, in the treatment of patients with mesothelioma. April 2001 LU22 A national randomised trial of surgical resection with or without pre-operative chemotherapy, in patients, with operable non-small cell lung cancer (NSCLC) of any stage. June 2000 attom A National study of Tamoxifen duration in early Breast Cancer

44 References Dr. F. Adab Consultant Clinical Oncologist University Hospital of North Staffordshire. Radiotherapy Department. Cancer Centre City General Hospital Stoke-on-Trent. Staffordshire. ST4 6 QG Telephone: Fax: fawzi.adab@uhns.nhs.uk Dr. A.Jamil Consultant Clinical Oncologist University Hospital of North Staffordshire. Radiotherapy Department. Cancer Centre City General Hospital Stoke-on-Trent. Staffordshire. ST4 6 QG Telephone: Fax: arshad.jamil@uhns.nhs.uk

45 - 45 -