Plant Biotechnology Pipeline

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1 Corn 4 th -Generation Herbicide Tolerance 3 rd -Generation Herbicide Tolerance Multiple Mode Enlist : 2,4-D & FOP 4 th -Generation Below- Ground Insect Protection 3 rd -Generation Above- Ground Insect Protection 4 th -Generation Above- Ground Insect Protection SmartStax PRO New Modes of Action Coleopteran III Optimum Leptra New Modes of Action Lepidopteran III Lepidopteran/Coleopteran DP nd -Generation CRW (Syngenta) Fungal Resistance Novel Insect Traits (Syngenta) (BASF) Nitrogen Use Efficiency Nitrogen Use Efficiency (Syngenta) CRW = Corn Rootworm Enlist = Dow AgroSciences herbicide trait providing tolerance to 2,4-D and FOP herbicides Stress Tolerance Stress Tolerance Stress Tolerance Drought Tolerance II Yield & Stress Corn II Yield & Stress Corn III

2 Soybean 4 th -Generation Herbicide Tolerance Roundup Ready 2 Xtend 3 rd -Generation Insect Protection 3 rd -Generation Herbicide Tolerance: Roundup Ready Xtend (Glyphosate + Dicamba tolerances) + 3 rd Mode of Action Hemiptera/Stink Bug Multiple Mode Lepidopteran HPPDi + Glufosinate (Syngenta, Bayer CropScience) Nematode Resistance SCN (Syngenta) Nematode Resistance SCN (Bayer CropScience) Nematode Resistance SCN (BASF, Monsanto) Disease Resistance ASR II Disease Resistance (Syngenta) Enlist : 2,4-D + Glufosinate Enlist E3 : 2,4-D + Glyphosate + Glufosinate (Dow AgroSciences, M.S. Technologies) Balance GT/LL: Glyphosate + HPPDi + Glufosinate (Bayer CropScience, M.S.Technologies) Balance GT: Glyphosate + HPPDi (Bayer CropScience, M.S.Technologies) Cultivance: Imidazolinone (BASF, Embrapa/Brazil) Fungal Resistance (BASF) / Enlist E3 + 2-Bt Trait: 2,4-D + Glyphosate + Glufosinate + 2 Bt Traits Next-Generation Higher Yielding 2 nd -Generation Insect Protection Increased Oil & Improved Feed Efficiency SCN = Soybean Cyst Nematode Bt = Bacillus thuringiensis ASR = Asian Soybean Rust RR = Roundup Ready LL = LibertyLink, tolerant to glufosinate herbicides HPPDi = Hydroxyphenylpyruvate deoxygenase inhibitor, family of herbicides Enlist = Dow AgroSciences herbicide trait providing tolerance to glyphosate, 2,4-D, glufosinate SDA Omega-3 Vistive Gold Low Saturated, Zero Trans-Fat Oil

3 Cotton Next-Generation Herbicide Tolerance (Bayer CropScience) Enlist Lygus Control / Bollgard II XtendFlex 4 th -Generation Bollgard / GlyTol TwinLink Plus: Glufosinate + Glyphosate + Expanded Insect Resistance (Bayer CropScience) Bollgard III GlyTol = Glyphosate Tolerant, tolerant to glyphosate herbicides Enlist = Dow AgroSciences herbicide trait providing tolerance to 2,4-D and glufosinate Contact individual trait developers for timelines and estimated WideStrike 3

4 Rice LL (Bayer CropScience) Dual Mode of Action Lepidopteran Golden Rice 1 Beta-carotene Content (IRRI/Philippines) (Bayer CropScience) Golden Rice 2 Beta-carotene Content (IRRI/Philippines) (BASF, Bayer CropScience) LL = LibertyLink, tolerant to glufosinate herbicides

5 Canola (Oilseed Rape) Dicamba Tolerance TruFlex Roundup Ready Healthy Fatty Acids (BASF, Cargill) Optimum GLY Oil Quality (Bayer CropScience) LL RR = Roundup Ready LL = LibertyLink, tolerant to glufosinate herbicides LL (Monsanto, Bayer CropScience) RR + LL (Bayer CropScience) TruFlex RR + LL (Bayer CropScience, Monsanto)

6 Other Crops Alfalfa Bean Eggplant Potatoes Sugarbeet (Monsanto, Forage Genetics International) Reduced Lignin Virus Resistance Virus Resistance (Monsanto, Forage Genetics International) Geminivirus (Embrapa/Brazil) Bt Brinjal (Maharashtra Hybrid Seeds Company) Potato Virus Y (Tecnoplant/Argentina) Sugarcane / (BASF, KWS) Insect-protected + Roundup Ready (BASF, CTC) Wheat I II Yield & Stress RR = Roundup Ready Bt = Bacillus thuringiensis

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