Structural Brain Changes in remitted Major Depression
|
|
|
- Alexander Andrews
- 7 years ago
- Views:
Transcription
1 Structural Brain Changes in remitted Major Depression Andreas Berger unter der Anleitung von Assoc.Prof. Priv.Doz. Dr. Lukas Pezawas Universitätsklinik für Psychiatrie und Psychotherapie Medizinische Universität Wien Juli 2014 Andreas Berger (Meduniwien) Structural Brain Changes in rmdd Juli / 26
2 Introduction There is no single pathology in MDD that could properly account for the illness. There are subtle alterations in brain structure associated with MDD. Such alterations are the topic of this thesis. Andreas Berger (Meduniwien) Structural Brain Changes in rmdd Juli / 26
3 Previous studies and brain regions Most reports are of gray matter volume reductions. Prominent brain regions: 1 Hippocampus 2 Basal ganglia 3 Medial prefrontal cortex 1 Subgenual anterior cingulate cortex (sacc) 2 Orbitofrontal cortex (OFC) Andreas Berger (Meduniwien) Structural Brain Changes in rmdd Juli / 26
4 Regions of interest Andreas Berger (Meduniwien) Structural Brain Changes in rmdd Juli / 26
5 There are several measures to choose from 1 Gray matter volume 2 Cortical thickness 3 Surface area 4... Andreas Berger (Meduniwien) Structural Brain Changes in rmdd Juli / 26
6 The radial unit hypothesis Rakic, P. (1988, Jul). Specification of cerebral cortical areas. Science 241 (4862), Mountcastle, V. B. (1997, Apr). The columnar organization of the neocortex. Brain 120 ( Pt 4), Andreas Berger (Meduniwien) Structural Brain Changes in rmdd Juli / 26
7 Objective Region-of-interest analysis Is there a group difference in sacc or OFC volume? Cortex-wide analysis Is there a group difference in cortical thickness or surface area anywhere in the cortex? Andreas Berger (Meduniwien) Structural Brain Changes in rmdd Juli / 26
8 Sample Participants were recruited via ads in Vienna and Dresden. Assessment included SCID-I, SCID-II, HAM-D. n = rmdd 108 lifetime-healthy age gender 128 female and 88 male MRI scanning was done using a 3 Tesla Siemens TIM Trio scanner with a 12-channel head coil. Anatomical images were acquired using MPRAGE with TR/TE = 2300/4.21ms, flip angle 9 degrees, inversion time 900ms, voxel size 1x1x1.1mm. Andreas Berger (Meduniwien) Structural Brain Changes in rmdd Juli / 26
9 MRI image processing using FreeSurfer Andreas Berger (Meduniwien) Structural Brain Changes in rmdd Juli / 26
10 MRI image processing using FreeSurfer Segmentation Andreas Berger (Meduniwien) Structural Brain Changes in rmdd Juli / 26
11 MRI image processing using FreeSurfer Tesselation Andreas Berger (Meduniwien) Structural Brain Changes in rmdd Juli / 26
12 MRI image processing using FreeSurfer Tesselation Andreas Berger (Meduniwien) Structural Brain Changes in rmdd Juli / 26
13 MRI image processing using FreeSurfer Pial surface Andreas Berger (Meduniwien) Structural Brain Changes in rmdd Juli / 26
14 MRI image processing using FreeSurfer Inflation Andreas Berger (Meduniwien) Structural Brain Changes in rmdd Juli / 26
15 MRI image processing using FreeSurfer Spherical projection Andreas Berger (Meduniwien) Structural Brain Changes in rmdd Juli / 26
16 Drawing of ROIs Mapped to each subject via the sphere Andreas Berger (Meduniwien) Structural Brain Changes in rmdd Juli / 26
17 Statistical Analysis using the General Linear Model y i = β 1 x i1 + β 2 x i2 + β 3 x i3 + ε i Andreas Berger (Meduniwien) Structural Brain Changes in rmdd Juli / 26
18 Results Andreas Berger (Meduniwien) Structural Brain Changes in rmdd Juli / 26
19 Result from region-of-interest analysis Group difference in gray matter volume of the left sacc 1100 lh.sacc.label 900 GrayVol (mean + residuals) lifetime_healthy Clinical.Status remitted_mdd_or_bpii Andreas Berger (Meduniwien) Structural Brain Changes in rmdd Juli / 26
20 Results from cortex-wide analysis Correlation of cortical thickness with age Andreas Berger (Meduniwien) Structural Brain Changes in rmdd Juli / 26
21 Results from cortex-wide analysis Correlation of cortical thickness with age vertex vertex thickness (mean + residuals) 2.5 thickness (mean + residuals) Age Age Andreas Berger (Meduniwien) Structural Brain Changes in rmdd Juli / 26
22 Results from cortex-wide analysis Interaction effect between surface area and clinical status Andreas Berger (Meduniwien) Structural Brain Changes in rmdd Juli / 26
23 Results from cortex-wide analysis Interaction effect between surface area and clinical status vertex area (mean + residuals) 0.5 Clinical.Status lifetime_healthy remitted_mdd_or_bpii Age Andreas Berger (Meduniwien) Structural Brain Changes in rmdd Juli / 26
24 Summary 1 Former patients have slightly larger left sacc volumes than lifetime-healthy participants. This is unexpected. 2 There is a strong correlation of cortical thickness and age even in relatively young people. This has been documented before. 3 The effect of age on the surface area of a premotor region depends on the clinical status. The meaning of this is unclear. Andreas Berger (Meduniwien) Structural Brain Changes in rmdd Juli / 26
25 Summary 1 Former patients have slightly larger left sacc volumes than lifetime-healthy participants. This is unexpected. 2 There is a strong correlation of cortical thickness and age even in relatively young people. This has been documented before. 3 The effect of age on the surface area of a premotor region depends on the clinical status. The meaning of this is unclear. Andreas Berger (Meduniwien) Structural Brain Changes in rmdd Juli / 26
26 Summary 1 Former patients have slightly larger left sacc volumes than lifetime-healthy participants. This is unexpected. 2 There is a strong correlation of cortical thickness and age even in relatively young people. This has been documented before. 3 The effect of age on the surface area of a premotor region depends on the clinical status. The meaning of this is unclear. Andreas Berger (Meduniwien) Structural Brain Changes in rmdd Juli / 26
27 Summary 1 Former patients have slightly larger left sacc volumes than lifetime-healthy participants. This is unexpected. 2 There is a strong correlation of cortical thickness and age even in relatively young people. This has been documented before. 3 The effect of age on the surface area of a premotor region depends on the clinical status. The meaning of this is unclear. Andreas Berger (Meduniwien) Structural Brain Changes in rmdd Juli / 26
28 How not to interpret statistics Andreas Berger (Meduniwien) Structural Brain Changes in rmdd Juli / 26
29 Danke für die Aufmerksamkeit! Andreas Berger (Meduniwien) Structural Brain Changes in rmdd Juli / 26
MRI DATA PROCESSING. Compiled by: Nicolas F. Lori and Carlos Ferreira. Introduction
MRI DATA PROCESSING Compiled by: Nicolas F. Lori and Carlos Ferreira Introduction Magnetic Resonance Imaging (MRI) is a clinical exam that is safe to the patient. Nevertheless, it s very important to attend
Adolescent Brain Development and Effects of Alcohol Use
Adolescent Brain Development and Effects of Alcohol Use Monica Luciana, Ph.D. Professor and Chair Department of Psychology and Center for Neurobehavioral Development University of Minnesota (lucia003@umn.edu)
NEURO M203 & BIOMED M263 WINTER 2014
NEURO M203 & BIOMED M263 WINTER 2014 MRI Lab 1: Structural and Functional Anatomy During today s lab, you will work with and view the structural and functional imaging data collected from the scanning
Reliability of MRI-derived measurements of human cerebral cortical thickness: The effects of field strength, scanner upgrade and manufacturer
www.elsevier.com/locate/ynimg NeuroImage 32 (2006) 180 194 Reliability of MRI-derived measurements of human cerebral cortical thickness: The effects of field strength, scanner upgrade and manufacturer
Neurobiology of Depression in Relation to ECT. PJ Cowen Department of Psychiatry, University of Oxford
Neurobiology of Depression in Relation to ECT PJ Cowen Department of Psychiatry, University of Oxford Causes of Depression Genetic Childhood experience Life Events (particularly losses) Life Difficulties
The Meeting of Meditation and Science
1. Meditation brings about changes in the brain in 8 weeks The Meeting of Meditation and Science Hugh Byrne October/November 2012 Science Daily, Mindfulness Meditation Training Changes Brain Structure
Current Industry Neuroimaging Experience in Clinical Trials Jerome Barakos, M.D.
Current Industry Neuroimaging Experience in Clinical Trials Jerome Barakos, M.D. Melbourne Australia March 28, 2012 Synarc Experience and Expertise Largest imaging service provider dedicated to clinical
Evaluation of a patient's ressource srengthening psychotherapeutic intervention in treatment of residual depression symptoms
PLEASE NOTE: This trial has been registered retrospectively. Trial Description Title Euthymic Therapy: a Randomised Controlled Trial Trial Acronym [---]* URL of the trial [---]* Brief Summary in Lay Language
Why do we have so many brain coordinate systems? Lilla ZölleiZ WhyNHow seminar 12/04/08
Why do we have so many brain coordinate systems? Lilla ZölleiZ WhyNHow seminar 12/04/08 About brain atlases What are they? What do we use them for? Who creates them? Which one shall I use? Brain atlas
Chapter 10. Summary & Future perspectives
Summary & Future perspectives 123 Multiple sclerosis is a chronic disorder of the central nervous system, characterized by inflammation and axonal degeneration. All current therapies modulate the peripheral
Artifacts caused by transcranial magnetic stimulation coils and EEG electrodes in T 2 *-weighted echo-planar imaging
Magnetic Resonance Imaging 18 (2000) 479 484 Technical Note Artifacts caused by transcranial magnetic stimulation coils and EEG electrodes in T 2 *-weighted echo-planar imaging J. Baudewig a,b, W. Paulus
University of California San Francisco, CA, USA 4 Department of Veterans Affairs Medical Center, San Francisco, CA, USA
Disrupted Brain Connectivity in Alzheimer s Disease: Effects of Network Thresholding Madelaine Daianu 1, Emily L. Dennis 1, Neda Jahanshad 1, Talia M. Nir 1, Arthur W. Toga 1, Clifford R. Jack, Jr. 2,
An fmri study on reading Hangul and Chinese Characters by Korean Native Speakers
언 어 치 료 연 구, 제14 권 제4호 Journal of Speech & Hearing Disorders 2005, Vol.14, No.4, 29 ~ 36 An fmri study on reading Hangul and Chinese Characters by Korean Native Speakers Hyo-Woon Yoon(Brain Science Research
Diseases of the Nervous System. Neal G. Simon, Ph.D. Professor, Dept of Biological Sciences Lehigh University
Diseases of the Nervous System Neal G. Simon, Ph.D. Professor, Dept of Biological Sciences Lehigh University Outline A. Stress-related Disorders 1. Emotional Circuitry: Key Components 2. The Hypothalamic
Chapter Fourteen. Emotion, Reward, Aggression, and Stress
Chapter Fourteen Emotion, Reward, Aggression, and Stress EMOTIONS! Emotions generally include a Physical component, and a Subjective component or quality, and a Valence Emotions a product of Evolution?
Activation neuroimaging studies - GABA receptor function - alcohol cues in alcoholism
Activation neuroimaging studies - GABA receptor function A - alcohol cues in alcoholism Professor David Nutt Psychopharmacology Unit, University of Bristol. MRC Clinical Sciences Centre, London. Study
Subjects: Fourteen Princeton undergraduate and graduate students were recruited to
Supplementary Methods Subjects: Fourteen Princeton undergraduate and graduate students were recruited to participate in the study, including 9 females and 5 males. The mean age was 21.4 years, with standard
32-Channel Head Coil Imaging at 3T
32-Channel Head Coil Imaging at 3T Thomas Benner Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA
Best prac*ce in data-sharing in neuroimaging and more. Thomas Nichols University of Warwick h?p://warwick.ac.uk/tenichols
Best prac*ce in data-sharing in neuroimaging and more Thomas Nichols University of Warwick h?p://warwick.ac.uk/tenichols OHBM Commi?ee on Best prac*ce in Data Analysis & Sharing (COBIDAS) History Created
Mapping Brain Changes Over Time during Development: Challenges, Limits and Potential
Mapping Brain Changes Over Time during Development: Challenges, Limits and Potential Guido Gerig University of Utah Scientific Computing and Imaging (SCI) Institute Gerig 09-2008 Outline 1. Imaging Technology
Numerisches Rechnen. (für Informatiker) M. Grepl J. Berger & J.T. Frings. Institut für Geometrie und Praktische Mathematik RWTH Aachen
(für Informatiker) M. Grepl J. Berger & J.T. Frings Institut für Geometrie und Praktische Mathematik RWTH Aachen Wintersemester 2010/11 Problem Statement Unconstrained Optimality Conditions Constrained
Preventing Dementia: The Depression-Diabetes Nexus
Preventing Dementia: The Depression-Diabetes Nexus Roger S McIntyre Assoc. Professor of Psychiatry and Pharmacology, University of Toronto Head, Mood Disorders Psychopharmacology Unit, University Health
Northwestern University Neuroimaging Data Archive (NUNDA)
Northwestern University Neuroimaging Data Archive (NUNDA) Great Leap Forward Lei Wang Feinberg School of Medicine Departments of Psychiatry and Behavioral Sciences, Radiology People Washington University
The Neuroscience of MBCT for Depression. Thorsten Barnhofer Freie Universitaet Berlin 11 th of April, 2014
The Neuroscience of MBCT for Depression Thorsten Barnhofer Freie Universitaet Berlin 11 th of April, 2014 The Problem: Recurrent Depression Lifetime prevalence of MDD about 25% More than 80% of people
Running Head: INTERNET USE IN A COLLEGE SAMPLE. TITLE: Internet Use and Associated Risks in a College Sample
Running Head: INTERNET USE IN A COLLEGE SAMPLE TITLE: Internet Use and Associated Risks in a College Sample AUTHORS: Katherine Derbyshire, B.S. Jon Grant, J.D., M.D., M.P.H. Katherine Lust, Ph.D., M.P.H.
How to test ocular movements in PSP Jan Kassubek
How to test ocular movements in PSP Jan Kassubek Universitätsklinik für Neurologie, Ulm Bedside Screening: PSP initially slowing of vertical saccades slowing of downward saccades is considered the hallmark
Constrained Tetrahedral Mesh Generation of Human Organs on Segmented Volume *
Constrained Tetrahedral Mesh Generation of Human Organs on Segmented Volume * Xiaosong Yang 1, Pheng Ann Heng 2, Zesheng Tang 3 1 Department of Computer Science and Technology, Tsinghua University, Beijing
Musculoskeletal MRI Technical Considerations
Musculoskeletal MRI Technical Considerations Garry E. Gold, M.D. Professor of Radiology, Bioengineering and Orthopaedic Surgery Stanford University Outline Joint Structure Image Contrast Protocols: 3.0T
The Brain. What is it? Neurons Glial Cells Connective Tissue Connective Fiber White Matter Grey Matter Cerebro-spinal Fluid
The Brain What is it? Neurons Glial Cells Connective Tissue Connective Fiber White Matter Grey Matter Cerebro-spinal Fluid A More Realistic View When we look at the brain we see mostly the Cerebral Cortex
Work-related diseases of occupational therapists - pilot study for creating an "occupational therapist-cohort" in Germany
Trial Description Title Work-related diseases of occupational therapists - pilot study for creating an "occupational therapist-cohort" in Trial Acronym ERGO-Study URL of the trial [---]* Brief Summary
Is there a Distinct Phenotype to Memory Loss in Alzheimer's Disease?
Is there a Distinct Phenotype to Memory Loss in Alzheimer's Disease? David A. Wolk, M.D. Assistant Director Penn Memory Center Assistant Professor of Neurology University of Pennsylvania 5 Million Clinical
Passive Infrared Hemoencephalography for Traumatic Brain Injury. Robert Coben, Ph.D., BCIA EEG, D-qEEG Neuropsychologist Massapequa Park, New York
Passive Infrared Hemoencephalography for Traumatic Brain Injury Robert Coben, Ph.D., BCIA EEG, D-qEEG Neuropsychologist Massapequa Park, New York pirheg Passive Infrared Hemoencephalography Over Fpz only
Recognizing and Treating Depression in Children and Adolescents.
Recognizing and Treating Depression in Children and Adolescents. KAREN KANDO, MD Division of Child and Adolescent Psychiatry Center for Neuroscience and Behavioral Medicine Phoenix Children s Hospital
Free software solutions for MEG/EEG source imaging
Free software solutions for MEG/EEG source imaging François Tadel Cognitive Neuroscience & Brain Imaging Lab., CNRS University of Paris - Hôpital de la Salpêtrière Cognitive Neuroimaging Unit, Inserm U562
Imaging Markers of Brain Network Dysfunction in Multiple Sclerosis
Faculty of Medicine & Health Sciences School of Medicine Radiological Sciences Research Group The University of Nottinham University Park Nottingham NG7 2RD t: +44 (0)115 823 0018 f: +44 (0)115 823 0004
Informatized Work and its Socio-Cultural Implications Caroline Roth-Ebner
Informatized Work and its Socio-Cultural Implications Caroline Roth-Ebner Alpen-Adria Universität Klagenfurt Wien Graz, Department of Media and Communication Studies Universitätsstrasse 65-67, 9020 Klagenfurt,
Brain Matters: Brain Anatomy
1 : Brain Anatomy Lesson Overview Students share what they already know about brain structure and function, and then, guided by descriptions of brain regions explore the G2C Online 3-D Brain to learn more
Depression in MS: Is brain imaging helpful?
Depression in MS: Is brain imaging helpful? Anthony Feinstein Professor, Department of Psychiatry Sunnybrook Health Sciences Centre & the University of Toronto Disclosures MS Society of Canada Canadian
2. MATERIALS AND METHODS
Difficulties of T1 brain MRI segmentation techniques M S. Atkins *a, K. Siu a, B. Law a, J. Orchard a, W. Rosenbaum a a School of Computing Science, Simon Fraser University ABSTRACT This paper looks at
Normal ranges of left ventricular global longitudinal strain: A meta-analysis of 2484 subjects
Normal ranges of left ventricular global longitudinal strain: A meta-analysis of 2484 subjects Teerapat Yingchoncharoen MD. Shikar Agarwal MD. MPH. Thomas H. Marwick MBBS. Ph.D. MPH. Cleveland Clinic Foundation
Assessment of regional grey matter loss in dementia with Lewy bodies: a surface based MRI analysis.
Assessment of regional grey matter loss in dementia with Lewy bodies: a surface based MRI analysis. Rosie Watson 1,2 Sean J. Colloby 1 Andrew M. Blamire 3 John T. O Brien 1,4 1 Institute for Ageing and
MEDIMAGE A Multimedia Database Management System for Alzheimer s Disease Patients
MEDIMAGE A Multimedia Database Management System for Alzheimer s Disease Patients Peter L. Stanchev 1, Farshad Fotouhi 2 1 Kettering University, Flint, Michigan, 48504 USA pstanche@kettering.edu http://www.kettering.edu/~pstanche
How are Parts of the Brain Related to Brain Function?
How are Parts of the Brain Related to Brain Function? Scientists have found That the basic anatomical components of brain function are related to brain size and shape. The brain is composed of two hemispheres.
Computational anatomic methods as applied to aging and dementia
The British Journal of Radiology, 000 (2008), 1 14 Computational anatomic methods as applied to aging and dementia 1,2 PAUL M THOMPSON, PhD and 1,2 LIANA G APOSTOLOVA, MD 1 Laboratory of NeuroImaging and
Neuroanatomy of developmental dyslexia. Franck Ramus CNRS Institut d Etude de la Cognition, Ecole Normale Supérieure, Paris
Neuroanatomy of developmental dyslexia Franck Ramus CNRS Institut d Etude de la Cognition, Ecole Normale Supérieure, Paris Environment Causal modelling of dyslexia Genetic difference Brain structure difference
Sheep Brain Dissection
Sheep Brain Dissection http://www.carolina.com/product/preserved+organisms/preserved+animals+%28mammal s%29/sheep+organs/preserved+sheep+dissection.do Michigan State University Neuroscience Program Brain
Mapping the Structural Core of Human Cerebral Cortex
Mapping the Structural Core of Human Cerebral Cortex PLoS BIOLOGY Patric Hagmann 1,2, Leila Cammoun 2, Xavier Gigandet 2, Reto Meuli 1, Christopher J. Honey 3, Van J. Wedeen 4, Olaf Sporns 3* 1 Department
ADHD AND ANXIETY AND DEPRESSION AN OVERVIEW
ADHD AND ANXIETY AND DEPRESSION AN OVERVIEW A/Professor Alasdair Vance Head, Academic Child Psychiatry Department of Paediatrics University of Melbourne Telephone: 9345 4666 Facsimile: 9345 6002 Email:
Application for Admission as a Guest Listener for the. Student Services Department Admission and Enrolment Office. Summer semester.
Application for Admission as a Guest Listener for the Summer semester Winter semester Student Services Department Admission and Enrolment Office Treskowallee Campus Building A Applicant: Please fill in
Methadone maintenance is the standard agonist
Article Acute Effect of Methadone Maintenance Dose on Brain fmri Response to Heroin-Related Cues Daniel D. Langleben, M.D. Kosha Ruparel, M.S.E. Igor Elman, M.D. Samantha Busch-Winokur, B.A. Ramapriyan
Auditory memory and cerebral reorganization in post-linguistically deaf adults
Auditory memory and cerebral reorganization in post-linguistically deaf adults Implications for cochlear implantation outcome D Lazard, HJ Lee, E Truy, AL Giraud Ecole Normale Supérieure, Inserm U960,
Pridmore S. Download of Psychiatry, Chapter 27. Last modified: December, 2013. http://eprints.utas.edu.au/287/
1 CHAPTER 27 FRONTAL LOBES BEDSIDE TESTING Introduction The frontal lobes, phylogenetically the youngest part, form over half the brain volume. Until recent decades the prefrontal areas were referred to
Integration and Visualization of Multimodality Brain Data for Language Mapping
Integration and Visualization of Multimodality Brain Data for Language Mapping Andrew V. Poliakov, PhD, Kevin P. Hinshaw, MS, Cornelius Rosse, MD, DSc and James F. Brinkley, MD, PhD Structural Informatics
Obtaining Knowledge. Lecture 7 Methods of Scientific Observation and Analysis in Behavioral Psychology and Neuropsychology.
Lecture 7 Methods of Scientific Observation and Analysis in Behavioral Psychology and Neuropsychology 1.Obtaining Knowledge 1. Correlation 2. Causation 2.Hypothesis Generation & Measures 3.Looking into
Multifamily Groups in the Treatment of Severe Psychiatric Disorders
Text from pages 7-12 of Multifamily Groups in the Treatment of Severe Psychiatric Disorders By William R. McFarlane (2002) ISBN 1-57230-743-9. Published by The guilford Press, 72 Spring Street, New York,
In conjunction with clinical history, structural
A QUICK GUIDE FOR NEUROIMAGING OF COMMON DEMENTIAS SEEN IN CLINICAL PRACTICE PRINT THIS ARTICLE David F. Tang-Wai, MDCM, FRCPC, assistant professor of neurology and geriatric medicine at the University
Mood Disorders. What Are Mood Disorders? Unipolar vs. Bipolar
Mood Disorders What Are Mood Disorders? In mood disorders, disturbances of mood are intense and persistent enough to be clearly maladaptive Key moods involved are mania and depression Encompasses both
MGH Adult Diffusion Data Scanning Protocols
MGH Adult Diffusion Data Scanning Protocols Structural scans SIEMENS MAGNETOM ConnectomA syngo MR D11 \\USER\INVESTIGATORS\Default\AAHScout_64 TA:0:14 PAT:3 Voxel size:1.6 1.6 1.6 mm Rel. SNR:1.00 :fl
The Effects of Musical Training on Structural Brain Development
THE NEUROSCIENCES AND MUSIC III: DISORDERS AND PLASTICITY The Effects of Musical Training on Structural Brain Development A Longitudinal Study Krista L. Hyde, a Jason Lerch, b Andrea Norton, c Marie Forgeard,
NeuroImage 61 (2012) 1428 1443. Contents lists available at SciVerse ScienceDirect. NeuroImage. journal homepage: www.elsevier.
NeuroImage 61 (2012) 1428 1443 Contents lists available at SciVerse ScienceDirect NeuroImage journal homepage: www.elsevier.com/locate/ynimg Measuring and comparing brain cortical surface area and other
Insular Dysfunction in People at Risk for Psychotic Disorders
Manuscript submitted to: Volume 2, Issue 2, 66-70. AIMS Neuroscience DOI: 10.3934/Neuroscience.2015.2.66 Received date 5 May 2015, Accepted date 8 June 2015, Published date 10 June 2015 Commentary Insular
CSE511 Brain & Memory Modeling. Lect04: Brain & Spine Neuroanatomy
CSE511 Brain & Memory Modeling CSE511 Brain & Memory Modeling Lect02: BOSS Discrete Event Simulator Lect04: Brain & Spine Neuroanatomy Appendix of Purves et al., 4e Larry Wittie Computer Science, StonyBrook
FIFTH BIENNIAL CONFERENCE ON RESTING STATE BRAIN CONNECTIVITY 2016 VIENNA
FIFTH BIENNIAL CONFERENCE ON SEPTEMBER 21 23/2016 Technical advances and methodological issues in measuring functional and structural brain connectivity: multimodal human imaging methods, animal models,
Preliminary U.S. FDA Outcomes of SMILE
Preliminary U.S. FDA Outcomes of SMILE D. REX HAMILTON, MD, MS, FACS HEALTH SCIENCES CLINICAL PROFESSOR OF OPHTHALMOLOGY MEDICAL DIRECTOR, UCLA LASER REFRACTIVE CENTER STEIN EYE INSTITUTE, GEFFEN SCHOOL
Morphological analysis on structural MRI for the early diagnosis of neurodegenerative diseases. Marco Aiello On behalf of MAGIC-5 collaboration
Morphological analysis on structural MRI for the early diagnosis of neurodegenerative diseases Marco Aiello On behalf of MAGIC-5 collaboration Index Motivations of morphological analysis Segmentation of
Sports Radiology : Making a diagnosis or solving a problem
Sports Radiology : Making a diagnosis or solving a problem Professor Dr John George University of Malaya Research Imaging Centre University of Malaya Medical Centre Kuala Lumpur, Malaysia. Abstract: Aim:
Lago di Como, February 2006
1 and Martin J Prince 1 1 Institute of Psychiatry, London Lago di Como, February 2006 1 Background to depression and 2 Study methods and measures 3 What does it all mean? 4 What does it all mean? Why was
MULTIPLE REGRESSION EXAMPLE
MULTIPLE REGRESSION EXAMPLE For a sample of n = 166 college students, the following variables were measured: Y = height X 1 = mother s height ( momheight ) X 2 = father s height ( dadheight ) X 3 = 1 if
Magnetic Resonance Imaging
Magnetic Resonance Imaging What are the uses of MRI? To begin, not only are there a variety of scanning methodologies available, but there are also a variety of MRI methodologies available which provide
Whole-brain Functional MR Imaging Activation from a Finger-tapping Task Examined with Independent Component Analysis
AJNR Am J Neuroradiol 21:1629 1635, October 2000 Whole-brain Functional MR Imaging Activation from a Finger-tapping Task Examined with Independent Component Analysis Chad H. Moritz, Victor M. Haughton,
Trends in Neuroscience and Education
Trends in Neuroscience and Education ] (]]]]) ]]] ]]] Contents lists available at SciVerse ScienceDirect Trends in Neuroscience and Education journal homepage: www.elsevier.com/locate/tine The effects
Drug Therapy and Cerebral Perfusion in Obsessive-Compulsive Disorder
Drug Therapy and Cerebral Perfusion in Obsessive-Compulsive Disorder V. Molina, R. Montz, M. MartIn-Loeches, A. Jimà nez-vicioso,j.l. Cameras and F.J. Rubia Department of Psychiatty, San Juan de Dios Hospital,
The Cortical Underpinnings of Context-based Memory Distortion
The Cortical Underpinnings of Context-based Memory Distortion The Harvard community has made this article openly available. Please share how this access benefits you. Your story matters. Citation Published
The Differential Effects of Three Mindfulness Techniques on Indicators of. Emotional Well-being and Life Satisfaction
The Differential Effects of Three Mindfulness Techniques on Indicators of Emotional Well-being and Life Satisfaction Marise Fallon BPsycSci (l-ions) A report submitted in partial requirement for the degree
Research Paper. 152 J Psychiatry Neurosci 2010;35(3)
Research Paper Medial prefrontal cortex activity during memory encoding of pictures and its relation to symptomatic improvement after citalopram treatment in patients with major depression Martin Roy,
Investigation of the effect of isomaltulose (PalatinoseTM) on metabolic parameters in subjects with Type 2 Diabetes.
PLEASE NOTE: This trial has been registered retrospectively. Trial Description Title Investigation of the effect of isomaltulose (PalatinoseTM) on metabolic parameters in subjects with Type 2 Diabetes.
Characterizing Structural Neural Networks
Characterizing Structural Neural Networks In Major Depressive Disorder using Diffusion Tensor Imaging A Dissertation Presented to The Academic Faculty by Ki Sueng Choi In Partial Fulfillment of the Requirements
Journal of Serendipitous and Unexpected Results
Journal of Serendipitous and Unexpected Results Neural Correlates of Interspecies Perspective Taking in the Post-Mortem Atlantic Salmon: An Argument For Proper Multiple Comparisons Correction Craig M.
Restructuring of companies a proposal for pre-insolvency restructuring proceedings Dr. Andrea Braun
Restructuring of companies a proposal for pre-insolvency Dr. Andrea Braun Institut für Interdisziplinäre Restrukturierung e.v. Pre-insolvency Restructuring Europe calling, Berlin busy? 21 May 2015 Overview
FUNCTIONAL EEG ANALYZE IN AUTISM. Dr. Plamen Dimitrov
FUNCTIONAL EEG ANALYZE IN AUTISM Dr. Plamen Dimitrov Preamble Autism or Autistic Spectrum Disorders (ASD) is a mental developmental disorder, manifested in the early childhood and is characterized by qualitative
NEW. CIRRUS HD-OCT 5000/500 Advancing Smart OCT. Imaging Applications: Anterior Segment Glaucoma Retina. International Version
NEW CIRRUS HD-OCT 5000/500 Advancing Smart OCT Imaging Applications: Anterior Segment Glaucoma Retina International Version NEW PanoMap Analysis Wide-field structural damage assessment for glaucoma NEW
Using Neuroscience to Understand the Role of Direct Mail
Millward Brown: Case Study Using Neuroscience to Understand the Role of Direct Mail Business Challenge Virtual media has experienced explosive growth in recent years, while physical media, such as print
NEUROIMAGING in Parkinsonian Syndromes
NEUROIMAGING in Parkinsonian Syndromes (Focus on Structural Techniques: CT and MRI) Dr. Roberto Cilia Parkinson Institute, ICP, Milan, Italy OUTLINE Primary Parkinsonism Idiopathic Parkinson s Disease
Symmetry of Cortical Folding Abnormalities in Williams Syndrome Revealed by Surface-Based Analyses
5470 The Journal of Neuroscience, May 17, 2006 26(20):5470 5483 Neurobiology of Disease Symmetry of Cortical Folding Abnormalities in Williams Syndrome Revealed by Surface-Based Analyses David C. Van Essen,
2 Neurons. 4 The Brain: Cortex
1 Neuroscience 2 Neurons output integration axon cell body, membrane potential Frontal planning control auditory episodes soma motor Temporal Parietal action language objects space vision Occipital inputs
Improving the Measurement Properties of Depressive Symptom Instruments for Use after SCI
Improving the Measurement Properties of Depressive Symptom Instruments for Use after SCI Allen Heinemann, PhD Ryan Williams, PhD Charles Bombardier, PhD Martin Forchheimer, MPP Jesse Fann, MD Holly Neumann,
imagic PRO Version 2.0 User Manual
imagic PRO Version 2.0 User Manual 2007 DISCLAIMER The imagic software is designed for use in medical research, it has not the status of a medical product, i.e. it is not allowed to use it directly or
Update: MRI in Multiple sclerosis
Nyt indenfor MS ved MR Update: MRI in Multiple sclerosis Hartwig Roman Siebner Danish Research Centre for Magnetic Resonance (DRCMR) Copenhagen University Hospital Hvidovre Dansk Radiologisk Selskabs 10.
NEW MEDICAL TECHNOLOGIES FOUNDATION
NEW MEDICAL TECHNOLOGIES FOUNDATION MEDICAL CENTER REPORT ON THE RESEARCH WORK «Influence exerced by the electromagnetic anomalies neutraliser on changes of EEG parameters caused by exposure to the electromagnetic
NeuroImage xxx (2011) xxx xxx. Contents lists available at SciVerse ScienceDirect. NeuroImage. journal homepage: www.elsevier.
NeuroImage xxx (2011) xxx xxx YNIMG-08796; No. of pages: 13; 4C: 4, 5, 6, 7, 8, 9, 10, 11, 12 Contents lists available at SciVerse ScienceDirect NeuroImage journal homepage: www.elsevier.com/locate/ynimg
Chapter 11, Risk and Return
Chapter 11, Risk and Return 1. A portfolio is. A) a group of assets, such as stocks and bonds, held as a collective unit by an investor B) the expected return on a risky asset C) the expected return on
Journal of Psychiatric Research
Journal of Psychiatric Research 45 (2011) 577e587 Contents lists available at ScienceDirect Journal of Psychiatric Research journal homepage: www.elsevier.com/locate/psychires Neural correlates of emotional
Functional brain mapping of the relaxation response and meditation
AUTONOMIC NERVOUS SYSTEM Functional brain mapping of the relaxation response and meditation Sara W. Lazar, 1,2,CA George Bush, 1,2 Randy L. Gollub, 1,2 Gregory L. Fricchione, 3,5 Gurucharan Khalsa and
Primary and Secondary Rewards Differentially Modulate Neural Activity Dynamics during Working Memory
Primary and Secondary Rewards Differentially Modulate Neural Activity Dynamics during Working Memory Stefanie M. Beck 1,2, Hannah S. Locke 1, Adam C. Savine 1, Koji Jimura 1, Todd S. Braver 1 * 1 Department
Effects of Achievement Goals on Challenge Seeking and Feedback Processing: Behavioral and fmri Evidence
on Challenge Seeking and Feedback Processing: Behavioral and fmri Evidence Woogul Lee, Sung-il Kim* Department of Education and bmri (Brain and Motivation Research Institute), Korea University, Seoul,
Nonlinear Regression:
Zurich University of Applied Sciences School of Engineering IDP Institute of Data Analysis and Process Design Nonlinear Regression: A Powerful Tool With Considerable Complexity Half-Day : Improved Inference
OLFACTORY PATHWAYS AND LIMBIC SYSTEM
903 Olfactory and Limbic OLFACTORY PATHWAYS AND LIMBIC SYSTEM I. OLFACTORY PATHWAYS The sense of smell is much less essential than vision, audition or the somatic senses, and will therefore receive less
Software Packages The following data analysis software packages will be showcased:
Analyze This! Practicalities of fmri and Diffusion Data Analysis Data Download Instructions Weekday Educational Course, ISMRM 23 rd Annual Meeting and Exhibition Tuesday 2 nd June 2015, 10:00-12:00, Room
Accurate prediction of V1 location from cortical folds in a surface coordinate system
www.elsevier.com/locate/ynimg NeuroImage 39 (2008) 1585 1599 Accurate prediction of V1 location from cortical folds in a surface coordinate system Oliver P. Hinds, a, Niranjini Rajendran, b Jonathan R.