Lung Cancer Center: How to Achieve JCI

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1 07/30/55 1 Lung Cancer Center: How to Achieve JCI Prof. Emeritus Sawang Saenghirunvattana M.D Copyright 2012

2 07/30/55 2 Technology TECHNOLOGY ROADMAP Emphasis valve EBUS GS AUTOFLUORESCENSE Virtual Bronchoscopy EBUS-TBNA VALVE STENT BALLOON ELECTROCAUTERY, ARGON PLASMA COAGULATION BRONCHOSCOPY BRACHY THERAPY /07/55 Copyright

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5 07/30/55 5 Lung Cancer Case sex Samitivej Hospital Bangkok Cancer Center Hospital Non smoking smoking Non smoking smoking Women Men /07/55 Copyright

6 07/30/55 6 Innovation, Research and Development Electrocautery to destroy airway cancer Pre ELECTROCAUTERY Post Timing = 30 sec min. MR= 0%

7 07/30/55 7 ARGON PLASMA COAGULATION TO DESTROY ENDOBRONCHIAL LUNG CANCER

8 07/30/55 8 Airway Obstruction

9 07/30/55 9

10 07/30/55 10 International Invited Presentation In 2007 Use of bronchial stent in lung cancer.asia Pacific Congress of Bronchology 15 Jul Singapore

11 07/30/55 11 Innovation, Research and Development Balloon occlusion in managing hemoptysis. Watanabe valve in managing lung bleb and bronchopleural fistula.

12 07/30/55 12 Innovation, Research and Development Brachy therapy Rigid bronchoscopy combination with fiberoptic bronchoscopy

13 07/30/55 13 EBUS Innovation, Research and Development

14 07/30/55 14 Prof. Noriaki Kurimoto

15 07/30/55 15

16 07/30/55 16 Takahiro Nakajima M.D. CHIBA, Tokyo

17 07/30/55 17 Squamous cell carcinoma

18 07/30/55 18 Squamous cell carcinoma

19 07/30/55 19 Squamous cell carcinoma

20 07/30/55 20 Granuloma

21 07/30/55 21 Granuloma

22 07/30/55 22 Metastatic adenocarcinoma

23 07/30/55 23 Diagnosis and Management of Lung Cancer Executive Summary: ACCP Evidence-Based Clinical Practice Guidelines (2 nd Edition ) W.Michael Alberts Chest 2007;132;1-19 DOI /chest

24 07/30/55 24 Initial Diagnosis of Lung Cancer In patients suspected of having SCLC based on radiographic and clinical finding, it is recommended that the diagnosis be confirmed by the easiest method (sputum cytology, thoracentesis, fine-needle aspirate,bronchoscopy including (TBNA),(EBUS - NA), ( EUS-NA ).Grade of recommendation, 1C

25 07/30/55 25 E-BUS Effectiveness in Samitivej Hospital % in detecting and staging of lung cancer, TB, Sarcoidosis. MR=0% European respiratory society, 2007 = 91 %

26 07/30/55 26 International Invited Presentation In 2007 Managing lung cancer. Asia Pacific Pulmonary Conference, 2 Dec 2007, Australia

27 07/30/55 27 Endobronchial Ultrasound-guided Transbronchial Needle Aspiration 2007 Sawang Saenghirunvattana, M.D. N = = TB 14 = CA LUNG 1 = Malignant Lymphoma Sensitivity = 96 % 15 th WCB 2008 TOKYO, JAPAN

28 07/30/55 28 Invited speaker EBUS TBNA Annual meeting Japan Society for Respiratory Endoscopy Jun 17,2011

29 07/30/55 29 Silver Award Virtual Bronchoscopy. European Respiratory Society 17 Sep 2007.Sweden

30 07/30/55 30 Sawang Saenghirunvattana, M.D.

31 07/30/55 31 Respiratory Tract

32 07/30/55 32 Image Comparison

33 07/30/55 33 Ultrasonic Miniature probes (Mini-Probe) Mini-Probes scanning miniature probes mechanical radial Can be passed down the channel of a standard endoscope to provide high quality ultrasound images.

34 07/30/55 34 Endobronchial Ultrasonography with a Guide Sheath (EBUS-GS) EBUS-GS is another new technique for obtaining specimens in suspected peripheral lung cancer.

35 07/30/55 35 Endobronchial Ultrasonography with a Guide Sheath (EBUS-GS) US Probe

36 07/30/55 36 The Advantages Locate peripheral pulmonary lesions. Increase the reliability of collection from lesions. Reduce procedure time by enabling physicians to return to the same lesion or site easily for multiple biopsies. Reduce damage to the bronchial wall with forceps passed through the sheath. Reduce radiation exposure since continued fluoroscopy is not necessary once the Guide Sheath position has been fixed. Improve the diagnostic rate for small lesions. Diagnose early lung cancer invasion.

37 07/30/55 37 Diagnostic yield affected the location of the lesion. Kurimoto N et al. Chest 2004;126: by American College of Chest Physicians

38 07/30/55 38 CASE STUDY

39 07/30/55 39 CASE STUDY march 2010 march 2012

40 07/30/55 40 Samitivej Sukumvit Hospital Noriaki Kurimoto, MD(National Hiroshima HP)

41 07/30/55 41

42 07/30/55 42 Tumor cells

43 07/30/55 43

44 07/30/55 44

45 07/30/55 45

46 07/30/55 46 Transbronchial biopsy

47 07/30/55 47

48 07/30/55 48

49 07/30/55 49

50 07/30/55 50 Normal bronchial cells

51 07/30/55 51 Permanent section of transbronchial biopsy

52 07/30/55 52

53 07/30/55 53 Fiberoptic fluorescense in early detection of lung cancer

54 07/30/55 54 Comparison of staging of the lung cancer in Thailand in percent Deesomchoke 2005 Samitivej 2008 Samitivej 2012 Stage Stage I,II Stage III,IV **ELCC 2012

55 07/30/55 55 PM4. Patient with a solitary nodule(<3cm) on chest X-ray or CT scan of the chest have diagnosis endpoints documented within 2 months. Target = 100 % Identification of malignant nodule is important because it may represent an early stage of lung cancer, so the patients with pulmonary nodule on chest x ray or CT scan in our program will have diagnosis endpoint within 2 months. Numerator Denominator Original source of measure Numbers of the patients without a prior diagnosis of cancer ( except non melanoma skin cancer ) with a solitary nodule (<3 cm )on chest X-ray or CT scan of the chest have diagnosis endpoints documented within 2 months of the radiological study Total numbers of the patients without a prior diagnosis of cancer ( except non melanoma skin cancer ) with a solitary nodule (<3 cm )on chest X-ray or CT scan of the chest Data collection from medical record Hospital information system ICD 10 (R 91) 30/07/55 Copyright

56 07/30/55 56 PM 4 : Patients with a solitary nodule (<3 cm) on chest x-ray or CT scan of the chest have diagnostic end points documented with in 2 months Percentage 17/20 44/47 Target 100% case : Benign lesion 1 case : Infection 2 cases : Regular follow up 1 case : loss follow up % 93.6% Refuse further investigation Have been diagnosed within 2 months 0 Oct-Dec' 2010 Jan-Sep' 2011 Year 30/07/55 Copyright

57 07/30/55 57 Finding Benign (BOOP, AVM, Bone island, Kissing spurs, Calcified granuloma) N = 67 cases 29 (43.28%) No true lesion 22 (32.84%) Infection (TB,Pneumonia,Acute bronchiolitis ) Refuse further investigation 12 (17.91% (TB=7.46%)) 3 (4.48%) CA lung 1 (1.49%) Result : PM4 Time to diagnosis :average days (1 day days) 30/07/55 Copyright

58 07/30/55 58 Benchmarking with International study The national lung screening trial * Samitivej Hospital CCPC Lung cancer N (Cases) 53, Non malignancy % % Lung cancer % 1.49 %** False negative 0.16% % 0% *NEJM Aug 4,2011,Vol. 365 No.5 The National Lung Screening Trial research team Reduced Lung- Cancer Mortality with Low-Dose Computed Tomographic Screening **Lung cancer in our data is less than NLST but there is a group of 3 cases : who suspicious of lung cancer refused future investigation 07/30/55 Copyright

59 07/30/55 59 Applicabilities 1. International benchmark. EBUS-TBNA effectivness 95 % 2. International PR and marketing 3. International training center (EBUS-TBNA ) - University of Delhi 2009, Work improvement ( KAISEN ) 5. Affiliated teaching hospital Chulalongkorn University : Occupational health. Rungsit University : Lung disease.

60 07/30/55 60 SWOT Analysis Strength Leading private hospital group Funding Applicable research Weakness - People - Researchers - Statistician Poor PR Evaluation, Reward Opportunity - State of the art technology - International network - JCI Threat - Government hospital - Foreign hospital - Publication

61 07/30/55 61 Future Research 2012 Multigene resistant analysis for proper target therapy

62 07/30/55 62

63 07/30/55 63

64 07/30/55 64

65 07/30/55 65 Multidisciplinary care team

66 07/30/55 66 Tumor conference 17/01/ /01/2012

67 07/30/55 67 Innovation, Research and Development

68 07/30/55 68 Acupuncture

69 07/30/55 69 Home health care 21/03/2012 visit home oxygen case

70 07/30/55 70 Bereavement 07/30/55 Copyright

71 07/30/55 71 Different cultures grieve in different ways, but all have ways that are vital in healthy coping with the death of a loved one. 07/30/55 Copyright

72 07/30/ /30/55 Copyright

73 07/30/55 73

74 07/30/55 74

75 07/30/55 75 Evaluation Continuous improvement (kaizen) of the product (EBUS) and process to be one of the best of the world Patient and family satisfaction

76 07/30/55 76 Inter-organization multidisciplinary team meeting Dr.Thelioza (UN Thailand) Case lung cancer TB Sarcoidosis

77 07/30/55 77 Domestic-alliance BNH : Lymphoma BDMS :Sarcoidosis Aik udorn :Lung cancer,tb SSH : Lung cancer Aikachol :Hemoptysis Praram 9 : Lung tumor Ramkhamhang: Lung disease

78 07/30/55 78 Potential customer Bangkok Christian Hospital

79 07/30/55 79 International multidisciplinary team meeting Noriaki Kurimoto, MD -pre-op visit,intra op -post op transfer patient back to Japan

80 07/30/55 80 International-alliance US: Lung cancer UK: Sarcoidosis France: Lung cancer Myanmar: Lung cancer Bangladesh: TB

81 07/30/55 81 Clinical Care Program Certification (CCPC) LUNG CANCER

Corporate Medical Policy Electromagnetic Navigation Bronchoscopy

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