Core Principles in Cellular Therapy, 3rd edition
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- Joel Woods
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1 Brochure More information from Core Principles in Cellular Therapy, 3rd edition Description: This handy text provides a focused look at hematopoietic and nonhematopoietic cellular therapy that will be useful to those working on the periphery as well as the mainstream of this exciting field. Written by experts, these chapters excerpted from the Technical Manual, 18th edition, were also peer-reviewed by the author's cellular therapy committee and subsection members. Together, these chapters capture what is essential to know about cellular therapy and regenerative medicine for example, new advances in induced pluripotent stem cells, mesenchymal stem cells, adipose-derived stem cells as well as more established cellular therapy products. Chapters include: - Collection and processing of cells collected from marrow harvests and apheresis procedures. - Umbilical cord blood uses and cord blood banking. - Clinical uses of nonhematopoietic cells blood- and marrow-derived. - Clinical uses of hematopoietic cells tissue-derived. - Transfusion support of HSCT recipients. Written by Aleksander M. Babic, MD, PhD; Jeanne E. Hendrickson, MD; Eapen K. Jacob, MD; Yameena Jawed, MD; Brian Johnstone, PhD; Scott A. Koepsell, MD, PhD; Mickey B. C. Koh, MD, PhD; Keith March, MD, PhD; David H. McKenna Jr, MD; Donna M. Regan, MT(ASCP)SBB; Edward R. Samuel, PhD, MSc; Garnet Suck, PhD, MSc; Sreedhar Thirumala, PhD; Christopher A. Tormey, MD Contents: Preface 1. The Collection and Processing of Hematopoietic Stem Cells Scott A Koepsell, MD, PhD; Eapen K Jacob, MD; and David H McKenna Jr, MD Clinical Utility Determination of Graft Source Collection/Sources of HSCs Processing Of HSCs Specialized Cell-processing Methods Cryopreservation Shipping And Transport of HSC Cellular Products Patient Care Other Regulatory Considerations Conclusion 2. Umbilical Cord Blood Banking Aleksandar M Babic, MD, PhD, and Donna M Regan, MT(ASCP)SBB Background Donor-Related Issues UCB Collection UCB Processing Shipment Receipt of UCB for Transplantation Thawing and Washing of UCB Infusion of UCB Economic Issues Regulations and Standards 3. Blood and Marrow-Derived Nonhematopoietic
2 Stem Cell Sources and Immune Cells for Clinical Applications Mickey B C Koh, MD, PhD; Edward R Samuel, PhD, MSc; and Garnet Suck, PhD, MSc Immune Cells for Clinical Therapy Induced Pluripotent Stem Cells Regulatory and Oversight Activities Conclusion 4. Tissue-Derived Non-Hematopoietic Stem Cell Sources for Use in Cell-Based Therapies Yameena Jawed, MD; Brian Johnstone, PhD; Sreedhar Thirumala, PhD; and Keith March, MD, PhD MSC Sources Properties of Clinical Relevance Isolation and Expansion Standardization of Methods for Isolation and Expansion of Clinical Product Cell Product Banking and Management of Supply Chain and End Use Therapeutic Applications of MSCs Current Research and Development: Focus on Cell Culture and Handling Conclusions and Future Directions 5. Transfusion Support for Hematopoietic Stem Cell Transplant Recipients Christopher A Tormey, MD, and Jeanne E Hendrickson, MD Implications Of ABO- and Non-ABO-Antigen-Incompatible Red Blood Cell Transplantation for Transfusion Blood Component Considerations Patients with Neutropenia and Infection that Is Unresponsive to Antimicrobial Therapy Special Processing of Blood Components for HSCT Recipients Special Considerations for Transfusions in Pediatric HSCT Recipients Information Portability for HSCT Recipients Index
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