BIOTECHNOLOGY SYNTHESIS CORTICOSTEROIDS FRANCOPIA PROSTAGLANDINS PRODUCT LIST JUNE 2013

Transcription

1 BIOTECHNOLOGY SYNTHESIS CORTICOSTEROIDS FRANCOPIA PROSTAGLANDINS PRODUCT LIST JUNE 2013 Validity of this document: December 2013

2 API Name Business Unit Page API Name Business Unit Page Acebutolol hydrochloride Synthesis P. 6 Acexamic acid Synthesis P. 6 Alimemazine tartrate Synthesis P. 6 Alprostadil alfadex (PGE1alfa-CD) Prostaglandins P. 12 Alprostadil (Prostaglandin E1) Prostaglandins P. 12 Altizide Synthesis P. 6 Amiodarone hydrochloride Synthesis P. 6 Amisulpride Synthesis P. 6 Apomorphine hydrochloride Francopia P. 10 Artesunate Biotech P. 14 Articaine hydrochloride Synthesis P. 6 Beraprost sodium Prostaglandins P. 12 Betaxolol hydrochloride Synthesis P. 6 Bimatoprost Prostaglandins P. 12 Budesonide micronized Corticosteroids and hormones P. 4 Buprenorphine hydrochloride Francopia P. 10 Buserelin acetate Synthesis P. 6 Canrenoate K Corticosteroids and hormones P. 4 Canrenone micronized Corticosteroids and hormones P. 4 Carbasalate calcium Synthesis P. 6 Carboprost tromethamine Prostaglandins P. 12 Cefodizime di-sodium Biotech P. 14 Chlorpromazine hydrochloride Synthesis P. 6 Ciclopirox acid powder Synthesis P. 6 Ciclopirox olamine powder Synthesis P. 6 Ciprofi brate Synthesis P. 6 Clobazam Synthesis P. 6 Clorazepate di potassium Synthesis P. 6 Codeine base Francopia P. 10 Codeine camphosulfonate Francopia P. 10 Codeine phosphate hemihydrate Francopia P. 10 Codeine resinate Francopia P. 10 Concentrate of poppy straw (morphine) Francopia P. 10 Concentrate of poppy straw (thebaine) Francopia P. 10 Cortisone acetate micronized Corticosteroids and hormones P. 4 Cyanocobalamin Biotech P. 14 Defl azacort micronized Biotech P. 14 Desoximetasone micronized Corticosteroids and hormones P. 4 Desoximetasone micronized sterile Corticosteroids and hormones P. 4 Dexamethasone micronized Corticosteroids and hormones P. 4 Dexamethasone acetate micronized Corticosteroids and hormones P. 4 Dexamethasone acetate micronized sterile Corticosteroids and hormones P. 4 Dexamethasone sodium metasulfobenzoate Corticosteroids and hormones P. 4 Dexamethasone sodium phosphate Corticosteroids and hormones P. 4 Dihydrocodeine hydrogen tartrate Francopia P. 10 Dinoprost (Prostaglandin F2 alpha) Prostaglandins P. 12 Dinoprost tromethamine Prostaglandins P. 12 Dinoprostone (Prostaglandin E2) Prostaglandins P. 12 Disopyramide Synthesis P. 7 DL Lysine acetyl salicylate (oral & injectable) Synthesis P. 7 DL Lysine acetyl salicylate + glycine (injectable) Synthesis P. 7 DL Lysine base 50 % Synthesis P. 7 Epoprostenol sodium Prostaglandins P. 12 Ethyl lofl azepate Synthesis P. 7 Ethylmorphine hydrochloride Francopia P. 10 Fexofenadine hydrochloride Synthesis P. 7 Flumethasone Corticosteroids and hormones P. 4 Fluorometholone micronized Corticosteroids and hormones P. 4 Fluticasone propionate micronized Corticosteroids and hormones P. 4 Framycetin sulphate (micronized, non micronized) Biotech P. 14 Framycetin sulphate low bio burden Biotech P. 14 Furosemide Synthesis P. 7 Glimepiride Synthesis P. 7 Gonadorelin acetate Synthesis P. 7 Human Recombinant Insulin Synthesis P. 7 Hydrocortisone acetate micronized Corticosteroids and hormones P. 4 Hydrocortisone acetate micronized sterile Corticosteroids and hormones P. 4 Hydrocortisone hemisuccinate Corticosteroids and hormones P. 4 Hydrocortisone micronized Corticosteroids and hormones P. 4 Hydrocortisone sodium phosphate Corticosteroids and hormones P. 5 Hydrocortisone valerate Corticosteroids and hormones P. 5 Hydromorphone hydrochloride Francopia P. 10 Hydroxocobalamin acetate Biotech P. 14 Hydroxocobalamin base Biotech P. 14 Hydroxocobalamin chloride Biotech P. 14 Hydroxychloroquine Synthesis P. 7 Iloprost Prostaglandins P. 12 Ketoprofen Synthesis P. 7 Latanoprost Prostaglandins P. 12 Lefl unomide Synthesis P. 7 Levomepromazine hydrochloride Synthesis P. 7 Levomepromazine maleate Synthesis P. 7 2

3 API Name Business Unit Page API Name Business Unit Page Levomethadone hydrochloride Francopia P. 10 Limaprost alfadex Prostaglandins P. 13 Loprazolam methanesulfonate Synthesis P. 7 Metamizol magnesium (powder and granules) Synthesis P. 7 Metamizol sodium Synthesis P. 7 Methadone hydrochloride Francopia P. 10 Methylprednisolone micronized Corticosteroids and hormones P. 5 Methylprednisolone acetate micronized Corticosteroids and hormones P. 5 Methylprednisolone hemisuccinate Corticosteroids and hormones P. 5 Methylprednisolone sodium succinate sterile Corticosteroids and hormones P. 5 Misoprostol pure substr. Prostaglandins P. 13 Molsidomine Synthesis P. 8 Morphine base Francopia P. 11 Morphine hydrochloride Francopia P. 11 Morphine sulfate Francopia P. 10 Nalbuphine hydrochloride Francopia P. 11 Naloxone hydrochloride Francopia P. 11 Naltrexone hydrochloride Francopia P. 11 Nedocromil sodium Synthesis P. 8 Norepinephrin hydrochloride Synthesis P. 8 (noradrenaline hydrochloride) Norepinephrin hydrogentartrate Synthesis P. 8 (noradrenaline tartrate) Opium crude Francopia P. 11 Opium powder Francopia P. 11 Oxybutynin hydrochloride Synthesis P. 8 Oxycodone hydrochloride Francopia P. 11 Pentoxifylline Synthesis P. 8 Pethidine hydrochloride Francopia P. 11 Pheniramine maleate Synthesis P. 8 Phenyltoloxamine resinate Francopia P. 11 Phenylhydrazine Synthesis P. 8 Piretanide Synthesis P. 8 Pitofenone hydrochloride Synthesis P. 8 Prednicarbate hydrochloride Synthesis P. 8 Prednisolone micronized Corticosteroids and hormones P. 5 Prednisolone acetate micronized Corticosteroids and hormones P. 5 Prednisolone acetate micronized sterile Corticosteroids and hormones P. 5 Prednisolone hemisuccinate Corticosteroids and hormones P. 5 Prednisolone micronized sterile Corticosteroids and hormones P. 5 Prednisolone sodium metasulfobenzoate Corticosteroids and hormones P. 5 Prednisolone sodium phosphate Corticosteroids and hormones P. 5 Prednisone micronized Corticosteroids and hormones P. 5 Pril Precursor: N-Acetyl-3-chloroalanine Synthesis P. 8 methyl ester Pril Precursor I:N-(1-S-Carbethoxy-3- Synthesis P. 8 phenylpropyl)-s-alanine Promethazine hydrochloride Synthesis P. 8 Ramipril (powder & coated) Synthesis P. 8 Rifampicin (rifampin) Biotech P. 14 Rifamycin S Biotech P. 14 Rifamycin SV Na Biotech P. 14 Riluzole Synthesis P. 8 Roxithromycin Biotech P. 14 Sodium cromoglicate granules Synthesis P. 9 Sodium cromoglicate micronized Synthesis P. 9 Sodium cromoglicate milled Synthesis P. 9 Sodium cromoglicate pellets Synthesis P. 9 Sodium cromoglicate recrystallized milled Synthesis P. 9 Sodium Hyaluronate sterile, Pharmaceutical Synthesis P. 9 grade, MW: million Da Sodium valproate Synthesis P. 9 Spiramycin base Biotech P. 14 Spironolactone micronized Corticosteroids and hormones P. 5 Sulpiride Synthesis P. 9 Tamsulosin hydrochloride Synthesis P. 9 Teicoplanin Biotech P. 14 Tetrazepam Synthesis P. 9 Thebaine base Francopia P. 11 Tiaprofenic acid Synthesis P. 9 Ticlopidine hydrochloride Synthesis P. 9 Tolterodine Synthesis P. 9 Travoprost Prostaglandins P. 13 Treprostinil Prostaglandins P. 13 Triamcinolone acetonide micronized Corticosteroids and hormones P. 5 Triamcinolone acetonide micronized sterile Corticosteroids and hormones P. 5 Trimipramine maleate Synthesis P. 9 Valproic acid Synthesis P. 9 Zolpidem tartrate Synthesis P. 9 Zopiclone Synthesis P. 9 3

4 BUSINESS UNIT CORTICOSTEROIDS & HORMONES Budesonide micronised Canrenoate K Canrenone micronized Cortisone acetate micronized Desoximetasone micronized Desoximetasone micronized sterile Dexamethasone micronized Dexamethasone acetate micronized Dexamethasone acetate micronized sterile Dexamethasone sodium metasulfobenzoate Dexamethasone sodium phosphate Flumethasone Under development Fluorometholone micronised Fluticasone propionate micronized Hydrocortisone acetate micronized Hydrocortisone acetate micronized sterile Hydrocortisone hemisuccinate Hydrocortisone micronized 4

5 BUSINESS UNIT CORTICOSTEROIDS & HORMONES Hydrocortisone sodium phosphate Hydrocortisone valerate Methylprednisolone micronized Methylprednisolone acetate micronized Methylprednisolone hemisuccinate Methylprednisolone sodium succinate sterile Prednisolone micronized Prednisolone acetate micronized Prednisolone acetate micronized sterile Prednisolone hemisuccinate Prednisolone micronized sterile Prednisolone sodium metasulfobenzoate Prednisolone sodium phosphate Prednisone micronized Spironolactone micronized Triamcinolone acetonide micronized Triamcinolone acetonide micronized sterile Contact: Pascal Tuchmuntz, +33 (1) , 5

6 BUSINESS UNIT SYNTHESIS Acebutolol hydrochloride Acexamic acid Alimemazine tartrate Altizide Amiodarone hydrochloride Amisulpride Articaine hydrochloride Betaxolol hydrochloride Buserelin acetate Carbasalate calcium Chlorpromazine hydrochloride Ciclopirox acid powder Ciclopirox olamine powder Ciprofi brate In progress Clobazam Clorazepate di potassium Disopyramide DL Lysine acetyl salicylate (oral & injectable) 6

7 BUSINESS UNIT SYNTHESIS DL Lysine acetyl salicylate + glycine (injectable) DL Lysine base 50 % Ethyl lofl azepate Fexofenadine hydrochloride Furosemide Glimepiride Gonadorelin acetate Human Recombinant Insulin Hydroxychloroquine Ketoprofen Lefl unomide Levomepromazine hydrochloride Levomepromazine maleate Loprazolam methanesulfonate Metamizol magnesium (powder and granules) Metamizol sodium Molsidomine 7

8 BUSINESS UNIT SYNTHESIS Nedocromil sodium Norepinephrin hydrochloride (noradrenaline hydrochloride) Norepinephrin hydrogentartrate (noradrenaline tartrate) Oxybutynin hydrochloride Pentoxifylline Pheniramine maleate Phenylhydrazine Piretanide Prednicarbate hydrochloride Pril Precursor: N-Acetyl-3-chloroalanine methyl ester Pril Precursor I:N-(1-S-Carbethoxy-3-phenylpropyl)- S-alanine Promethazine hydrochloride Ramipril (powder & coated) Riluzole Sodium cromoglicate granules Sodium cromoglicate micronized 8

9 BUSINESS UNIT SYNTHESIS Sodium cromoglicate milled Sodium cromoglicate pellets Sodium cromoglicate recrystallized milled Sodium Hyaluronate sterile, Pharmaceutical grade, MW: million Da Sodium valproate Sulpiride Tamsulosin hydrochloride In progress Tetrazepam Tiaprofenic acid Ticlopidine hydrochloride Tolterodine In progress Trimipramine maleate Valproic acid Zolpidem tartrate Zopiclone Contact: Christina Da Cunha, +33 (1) , 9

10 BUSINESS UNIT FRANCOPIA Apomorphine hydrochloride Buprenorphine Hydrochloride Codeine base In progress Codeine camphosulfonate Codeine Phosphate hemihydrate Codeine resinate Concentrate of poppy straw (morphine) Concentrate of poppy straw (thebaine) Dihydrocodeine hydrogen tartrate Ethylmorphine hydrochloride In progress Hydromorphone hydrochloride Levomethadone hydrochloride Methadone hydrochloride Morphine base Morphine hydrochloride Morphine sulfate 10

11 BUSINESS UNIT FRANCOPIA Nalbuphine hydrochloride Naloxone hydrochloride Naltrexone hydrochloride Opium crude Opium powder Oxycodone hydrochloride Pethidine hydrochloride Phenyltoloxamine resinate Thebaine base Contact: +33 (1)

12 BUSINESS UNIT PROSTAGLANDINS Alprostadil alfadex (PGE1alfa-CD) Alprostadil (Prostaglandin E1) Beraprost sodium Bimatoprost Carboprost tromethamine Dinoprost (Prostaglandin F2 alpha) Dinoprost tromethamine Dinoprostone (Prostaglandin E2) Epoprostenol sodium Iloprost Latanoprost In progress In progress Limaprost alfadex Misoprostol pure substr. In progress Travoprost Treprostinil Contact: Ervin Vajda, +36 (1) , 12

13 NOTES 13

14 BUSINESS UNIT BIOTECHNOLOGY Artesunate Cefodizime di-sodium Cyanocobalamin Defl azacort micronized Framycetin sulphate (micronized, non micronized) Framycetin sulphate low bio burden Hydroxocobalamin acetate Hydroxocobalamin base Hydroxocobalamin chloride Rifampicin (rifampin) Rifamycin S Rifamycin SV Na Roxithromycin Spiramycin base Teicoplanin Contact: Isabelle Messager, +33 (1) , isabelle.messager@sanofi.com 14

15 NOTES 15

16 20, avenue Raymond Aron F Antony Cedex - France - Tel: Communication: catherine.ortet@sanofi.com photos: SANOFI, Shutterstock - Document imprimé par un imprimeur labellisé Imprim'Vert, sur papier FSC recyclé avec des encres végétales. June 2013