OME : Mobile Cognitive Healthcare for the Consumer. Michael Nova, M.D. Chief Innovation Officer Pathway Genomics

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1 OME : Mobile Cognitive Healthcare for the Consumer Michael Nova, M.D. Chief Innovation Officer Pathway Genomics

2 90 % OF ALL THE WORLD S DATA WAS CREATED IN THE LAST 2 YEARS BIG DATA AND OMICS IN MEDICINE MEDICAL INFORMATION DOUBLES EVERY 3 YEARS, and by 2020 will double every 3 days.

3 DATA IS WORTHLESS UNLESS IT CAN BE ANALYZED AND ACTED ON.

4 HOW BIG IS BIG (DATA)? Whole genome sequence All the word s recorded music as of 2011 Library of congress digital holdings as of 2012 Weather modeling anticipated to produce first single-discipline exabyte dataset In 2010 the world produced 1.27b

5 A Single Person s HEALTH DATA a single person will generate 1 million gigabytes (1 Terabyte) of health-related data across his or her lifetime. That s as much data as in 300 million books. Rob Merkel, IBM,

6 Big Data Healthcare Cost Saving

7 OPPORTUNITIES TRENDS Healthcare TRANSFORMATION We believe Healthcare Transformation revolves around three business trends and two key opportunities for differentiation Evolution of Care Delivery Data + Ecosystem Convergence Movement to Consumerism Game Changing Analytical Insight What should I do? Flexible Adoption of Business Models Mobile, TeleHealth, Cognitive 7

8 The Human GENOME AND MEDICAL DATA 22,000 GENES 6 BILLION DNA LETTERS 49 $1,000 CHROMOSOMES COST TO SEQUENCE 70 % T E S T D A T A OF PATIENT S PERMANENT HEALTH RECORD IS MADE UP OF CLINICAL LABORATORY 8

9 Healthcare TRENDS 9

10 Healthcare Costs Driven by Obesity 74% of all costs are confined to obesity and related conditions

11 Mobile Tech AN APP FOR THE HUMAN GENOME Source: Topol, 2014 killer app will connect genetic variants to environmental, lifestyle, dietary, and activity related factors, guiding both sick and healthy people towards a fundamentally better quality of life.. Source: Apple Healthcare,

12 PROBLEM SPACE IN HEALTHCARE UNDERSTANDING & RELATING MANY DATA SETS

13 The New Era Of Cognitive Computing and A.I Dartmouth AI Conference Fast CPU/VPU Hierarchical Algorithms Weak AI Strong AI (AGI) Deep Learning Supervised Unsupervise d 13

14 COGNITIVE HEALTHCARE CLINICAL, FITNESS AND WELLNESS OME DIGITAL HEALTH PLATFORM AND DEEP LEARNING

15 WHAT A CONSUMER WANTS FOR HEALTHCARE Plan A Plan B Understand my needs Select my Doc or Benefit Manage and Improve My Health Get Health and Wellness Services Get Health and Wellness Goods Seek Information and Support Content Needs SHORT-TERM MID-TERM LONG-TERM

16 Trusting Health Apps In 2016, Users Will Trust Health Apps More Than Their Doctors... (DEC 31, 2015 FORBES) 79 percent (%) of Americans said they would be willing to use a wearable device to manage their health

17 RISING POPULARITY OF mhealth APPS (2014) US User # s Weight Loss 50 Million Exercise 26.5 Million Women's Health 10.5 Million Sleep & Medication 8 Million Pregnancy 7.5 Million Tools & Medication 6 Million Other 18 Million Source: Forbes 2015

18 APP Stores - #1 Distribution Channel APP stores number one distribution channel for mhealth apps - MAW Feb 2016 Distribution through other channels, such as via doctors, hospitals, or pharmacies are increasingly seen to be weaker channels through which to distribute a successful app solution.

19 mhealth MARKET IN BILLION PEOPLE WORLDWIDE WILL OWN A SMARTPHONE ½ WILL USE HEALTH APPS THE TOTAL GLOBAL mhealth MARKET WILL REACH $26 BILLION

20 What is OME? Ome is the world s first precision health and wellness mobile application using artificial intelligence (A.I.) and genetics to help provide consumers with precision information.

21 What is cool about AI/Cognitive and Healthcare? Biodata and NLP allows users to ask questions in everyday language that is translated into a Query to search for correct responses OME gets more accurate the more it is used; Dynamic Content We can accommodate client specific content (EHR, Genetic/WGS test, health survey, insurance); PHI is personal (HIPPA, etc.) Useful for many industries: Hospitals, Automotive, HR groups, Energy, Government, Telco, Hotels/Hospitality, etc Employee safety, greater productivity, less absenteeism, "precision" healthcare

22 Creating PERSONALIZED RESULTS 22

23 ENABLES YOU TO TAKE CHARGE

24 OME - USE INFORMATION GATHERING AND CURATION QUESTION: WHAT SHOULD I DO FOR MY WORKOUT TODAY? ANSWER: YOU COULD GO FOR 2 MILE RUN IN CENTRAL PARK, TAKE 100MGS ADVIL AND DRINK ONE COFFEE FIRST (NO SUGAR), because of your CYP1A2 gene you are a slow metabolizer of caffeine, AND BE CLOSER TO EARNING 100 POINTS FROM VITALITY HEALTHCARE. BRING YOUR FITBIT. WHY DON T YOU INVITE RUNNERDUDE100?

25 REAL TIME EVENT ACTIONABILTY OME : IF YOU RUN 2 MILES TODAY YOU CAN ENJOY DINNER AT PAIZON S MEDITERRANEAN, NEAR YOU NOW, AS PART OF YOUR DIET PLAN.

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31 The Future PATHWAY OME The Pathway OME Mobile App Healthcare Simplified Michael Nova M.D. Chief Innovation Officer Pathway Genomics 31