Eşdeğer Kolon Tablosu na İlişkin Açıklamalar

Transcription

1 Eşdeğer Kolon Tablosu na İlişkin Açıklamalar 1. Muadil kolon sıralamasında The United States Pharmacopeia (USP) kurumunun Column Equivalency Application listesi esas alınmıştır. Bu liste ekte bulunmaktadır. 2. Kolon sıralamasına Column comparison function (F) Kolon Karşılaştırma Fonksiyonu (F s ) esas teşkil etmiştir. Tabloya, benzer kolonlar için uygun kabul edilen sınır değer F s = 10 a kadar olan kolonlar dahil edilmiştir. Fonksiyon formülü ve değerlerine ilişkin geniş açıklama Teknik Kaynaklar bölümünde Kolonlar başlığında bulunmaktadır. 3. Her Kolon için USP tarafından kategorize edilmiş L Faz Spesifikasyonları, karşılaştırmayı kolaylaştırmak için Kolonları ve eşdeğer kolonlar için tabloda belirtilmiştir. 4. ChrometiSIL, % 99,999 saflık oranına sahip Silis jeli tabanlı kolon dolgu maddeleri, rakiplerinden farklı olarak kullanıcılara daha geniş bir analitik kullanım sahasını mümkün kılmak için, fazla sayıda modifikasyonlu faz içermektedir. Bundan dolayı ChrometiSIL fazlarının diğer üreticilerin fazlarında her zaman bir eşdeğeri bulunmamaktadır. Örneğin sadece C18 fazı için ChrometiSIL ürün ailesinde C18 ace-eps, C18 H, C18 SH, C18 AQ ve C18 AQ PLUS; ChromPEARL ürün ailesinde ise sub2 TPP C18 ace-eps ve sub2 NPP C18 ace-eps fazları sunulmaktadır. Diğer üreticilerde bu fazlara karşılık olarak yalnızca alışılagelmiş C18 fazı sunulmaktadır.

2 1. Kolonumuz ChrometiSIL C30 Faz C30 US-Pharmacopeia Sınıfı L62 Eşdeğer Kolonlar Vision C18 B Alltima HP C18 EPS Eşdeğer Üretici US-Pharmacopeia Sınıfı 2. ChrometiSIL C18 SH C18 SepaxGP-C18 Sepax Xterra MS C18 Acclaim 120 C18 Cogent HPS C18 MicroSolv ACE 5 C18 Genesis C18 120A Chromolith RP18e TSKgel Super-ODS TOSOH Bioscience OmniSpher 5 C18 PRECISION C18 Develosil ODS-UG-5 Armor C18 3um Advantage Armor C18 120A Unison UK-C18 Imtakt Hypersil Beta Basic-18 TSKgel ODS-140HTP TOSOH Bioscience Alltima C18 CAPCELL C18 M G Shiseido TSKgel Super-Octyl TOSOH Bioscience CAPCELL C18 SG120 Shiseido Kromasil 100-5C18 Akzo Nobel Nucleosil C18 HD Discovery C18 GROM-SIL 120 ODS-3 CP Grace-Grom SepaxHP-C18 Sepax Develosil ODS-HG-5 Wakosil II 5C18AR SGE COSMOSIL AR-II Nacalai Tesque XBridge C18 Cadenza 5CL-C18 Imtakt /Silvertone Sciences Inertsil WP300 C8 Halo-C18 Advanced Materials Technology Hypurity C18 Ascentis Express C18 Acclaim 120 C8 Denali (120A C18) Grace/Vydac Alltima HP C18 Grace/Vydac Purospher STAR RP18e PRECISION C8 GROM-SIL 120 ODS-5 ST Grace-Grom Xterra MS C8 Hichrom RPB HiChrom TSKgel Octyl-80Ts TOSOH Bioscience Genesis AQ 120A Hypersil GOLD C8 Genesis EC C8 120A Develosil C30-UG-5 L62 Kromasil 100-5C8 Akzo Nobel Zorbax Extend C18 Restek Ultra C18 Restek Genesis C8 120A Aqua C18 Alltima HP C8 Inertsil WP300 C18 CAPCELL C18 ACR Discovery C8 Discovery BIO Wide pore C18 Shiseido Hypersil Beta Basic-8 Polaris C18-Ether ACE 300 C8 Precision C8-PE Atlantis dc18 b Restek Ultra C8 Restek GraceSmart RP 18 5u Vydac Everest Grace/Vydac CAPCELL C18 UG120 Shiseido Wakosil II 5C18HG SGE ACE C4 L26 TSKgel ODS-80Ts TOSOH Bioscience YMC Basic LiChrospher 60 RP-Select B Targa C18 Higgens Zorbax Eclipse Plus C18 Hypurity C8

3 3. ChrometiSIL C8 SH C8 LiChrospher 60 RP-Select B Genesis AQ 120A Bondclone C18 SepaxHP-C18 Sepax Genesis C8 120A Nucleosil C18 HD Precision C8-PE TSKgel Super-Phenyl TOSOH Bioscience Aqua C18 GraceSmart RP 18 5u ACE C4 L26 HxSil C8 Hamilton Advantage Armor C18 120A PRECISION C8 Prevail C8 Atlantis T3 Atlantis dc18 b ACE AQ Armor C18 3um Betasil Phenyl-Hexyl Nucelosil C8 HD Inertsil WP300 C8 Curosil-PFP TSKgel ODS-80Ts QA TOSOH Bioscience Unison UK-C18 Imtakt Genesis EC C8 120A Targa C18 Higgens Nucleodur Sphinx RP YMC Basic Cogent HPS C18 MicroSolv Alltima C18 TSKgel Octyl-80Ts TOSOH Bioscience Genesis C4 EC 120A L26 Zorbax Eclipse XDB-CN ACE 5 CN PRECISION C18 Zorbax Rx-C8 Precision C18-PE Zorbax XDB-Phenyl 1 TSKgel ODS-80Ts TOSOH Bioscience Zorbax StableBond 300A C8 Discovery BIO Wide pore C5 SepaxBio-C4 Sepax Zorbax StableBond 80A C8 Develosil C30-UG-5 L62 Hypersil GOLD C8 ACE 300 C8 SepaxGP-Phenyl Sepax Kromasil 100-5C8 Akzo Nobel Alltima HP C8 Develosil ODS-MG-5 Acclaim 120 C8 Polaris C8-Ether Zorbax StableBond 300A C3 L56 CAPCELL C18 M G Shiseido Partisil C8 Polaris C18-Ether Genesis C18 120A Xterra Phenyl 1 Discovery C8 Xterra MS C8 SepaxGP-C18 Sepax HyPurity C4 L26 Alltima HP C18

4 4. ChrometiSIL C1 C1 TSKgel Super-Phenyl TOSOH Bioscience Prevail C8 HxSil C8 Hamilton ACE AQ Zorbax StableBond 300A C3 L56 Bondclone C18 SepaxGP-Phenyl Sepax LiChrospher 60 RP-Select B Zorbax XDB-Phenyl 1 Zorbax Eclipse XDB-CN 0 Betasil Phenyl-Hexyl Precision C8-PE Zorbax Rx-C8 Nucleodur Sphinx RP Genesis C8 120A Ultra PFP Restek Genesis C4 EC 120A ACE C4 L26 Zorbax StableBond 80A C8 Genesis AQ 120A Atlantis T3 Partisil C8 Atlantis dc18 b GraceSmart RP 18 5u TSKgel ODS-80Ts QA TOSOH Bioscience SepaxHP-C18 Sepax ACE 5 CN Nucelosil C8 HD Luna Phenyl-Hexyl Aqua C18 Curosil-PFP BetaMax Base PRECISION C8 Targa C18 Higgens Nucleosil C18 HD Synergi Polar-RP 5. ChrometiSIL C18 ace-eps C18 ace-eps Eşdeğer kolonu bulunmamaktadır Gemini C18 110A 6. ChrometiSIL C18 AQplus C18 AQ+ Alltima C18-WP 7. ChrometiSIL C18 H C18 H Genesis C18 120A Genesis C18 120A Xterra MS C18 ACE 5 C18 Armor C18 3um SepaxGP-C18 Sepax Develosil ODS-UG-5 Cogent HPS C18 MicroSolv Hypersil Beta Basic-18 TSKgel Super-Octyl TOSOH Bioscience TSKgel Super-ODS TOSOH Bioscience PRECISION C18 Nucleosil C18 HD Chromolith RP18e Advantage Armor C18 120A Unison UK-C18 Imtakt Discovery C18 Acclaim 120 C18 XBridge C18 Inertsil WP300 C8 Develosil ODS-HG-5 Alltima C18 Alltima HP C18 SepaxHP-C18 Sepax

5 7. ChrometiSIL C18 H C18 H CAPCELL C18 M G Shiseido PRECISION C8 Hypurity C18 Polaris C18-Ether Alltima HP C8 OmniSpher 5 C18 ACE 300 C8 Hypersil GOLD C8 Develosil C30-UG-5 L62 GROM-SIL 120 ODS-3 CP Grace-Grom Discovery C8 Acclaim 120 C8 TSKgel Octyl-80Ts TOSOH Bioscience Discovery BIO Wide pore C18 Hypersil Beta Basic-8 Inertsil WP300 C18 Genesis EC C8 120A CAPCELL C18 SG120 Shiseido Hichrom RPB HiChrom Hypurity C8 Hypersil GOLD GROM-SIL 120 ODS-5 ST Grace-Grom Genesis AQ 120A TSKgel ODS-140HTP TOSOH Bioscience Genesis C8 120A ACE C4 L26 Zorbax Eclipse XDB-C18 Aqua C18 Kromasil 100-5C8 Akzo Nobel COSMOSIL AR-II Nacalai Tesque Precision C8-PE YMC Basic Denali (120A C18) Grace/Vydac LiChrospher 60 RP-Select B HyPurity C4 L26 Kromasil 100-5C18 Akzo Nobel Xterra MS C8 SepaxBio-C4 Sepax SepaxBio-C8 Sepax GraceSmart RP 18 5u ACE 5 C4-300 L26 Cadenza 5CL-C18 Imtakt /Silvertone Sciences Nucelosil C8 HD Restek Ultra C8 Restek Atlantis dc18 b BioBasic-4 Symmetry 300 C18 Wakosil II 5C18AR SGE Chromegabond WR C8 ES Industries Vydac Everest Grace/Vydac Atlantis T3 Jupiter300 C5 Discovery BIO Wide pore C5 Discovery BIO Wide pore C8 Targa C18 Higgens DeltaPak C18 300A TSKgel ODS-80Ts TOSOH Bioscience CAPCELL C18 ACR Shiseido SepaxBioC18 Sepax

6 8. ChrometiSIL C18-AQ C18 AQ Armor C18 3um Genesis C18 120A Cogent HPS C18 MicroSolv Xterra MS C18 ACE 5 C18 Alltima HP C18 Develosil ODS-UG-5 Polaris C18-Ether Unison UK-C18 Imtakt Nucleosil C18 HD Hypersil Beta Basic-18 SepaxGP-C18 Sepax Discovery C18 ACE 300 C8 Develosil C30-UG-5 L62 Inertsil WP300 C8 XBridge C18 Advantage Armor C18 120A TSKgel Super-ODS TOSOH Bioscience TSKgel Super-Octyl TOSOH Bioscience PRECISION C18 Alltima HP C8 Inertsil WP300 C18 Hypurity C18 Develosil ODS-HG-5 Alltima C18 PRECISION C8 Hypersil GOLD Chromolith RP18e SepaxHP-C18 Sepax Hypersil GOLD C8 CAPCELL C18 M G Shiseido Hypurity C8 LiChrospher 60 RP-Select B GROM-SIL 120 ODS-5 ST Grace-Grom Discovery C8 Hichrom RPB HiChrom GROM-SIL 120 ODS-3 CP Grace-Grom Acclaim 120 C18 Discovery BIO Wide pore C18 ACE C4 L26 TSKgel Octyl-80Ts TOSOH Bioscience Aqua C18 Hypersil Beta Basic-8 ACE 5 C4-300 L26 Genesis AQ 120A Genesis C8 120A Acclaim 120 C8 Genesis EC C8 120A SepaxBio-C8 Sepax CAPCELL C18 SG120 Shiseido BioBasic-4 OmniSpher 5 C18 GraceSmart RP 18 5u HyPurity C4 L26 Precision C8-PE COSMOSIL AR-II Nacalai Tesque SepaxBio-C4 Sepax YMC Basic Denali (120A C18) Grace/Vydac DeltaPak C18 300A SepaxBioC18 Sepax Symmetry 300 C18 Kromasil 100-5C8 Akzo Nobel Cadenza 5CL-C18 Imtakt /Silvertone Sciences Discovery BIO Wide pore C8 Nucelosil C8 HD Chromegabond WR C8 ES Industries Hichrom RPB HiChrom Zorbax Eclipse XDB-C18 TSKgel ODS-140HTP TOSOH Bioscience Bondclone C18 Atlantis dc18 b Pursuit C18 Xterra MS C8 Discovery BIO Wide pore C5 Polaris C18-A Atlantis T3 Jupiter300 C18 Curosil-PFP Kromasil 100-5C18 Akzo Nobel

7 9. ChrometiSIL C8 ace-eps C8 ace-eps Eşdeğer kolonu bulunmamaktadır 10. ChrometiSIL CN EC CN EC 0 BetaMax Base BetaBasic CN 0 Genesis C4 EC 120A L26 Betasil Phenyl-Hexyl SepaxHP-Cyano Sepax Zorbax Eclipse XDB-CN 0 Nucleodur Sphinx RP Hypurity Cyano 0 SepaxGP-C4 Sepax Ultra PFP Restek Kromasil 100-5C4 Akzo Nobel L26 Discovery BIO Wide pore C5 SepaxGP-Phenyl Sepax Atlantis dc18 b ACE AQ Precision C8-PE Atlantis T3 Luna Phenyl-Hexyl Polaris C8-Ether YMC Basic Xterra MS C8 ACE C4 L26 Nucelosil C8 HD Symmetry 300 C4 L26 SepaxBio-C4 Sepax Develosil ODS-MG-5 Zorbax XDB-Phenyl 1 Genesis AQ 120A TSKgel Octyl-80Ts TOSOH Bioscience TSKgel ODS-80Ts QA TOSOH Bioscience Precision CN 0 TSKgel Super-Phenyl TOSOH Bioscience Kromasil 100-5C8 Akzo Nobel Xterra Phenyl 1 Zorbax StableBond 300A C3 L56 Acclaim 120 C8 Curosil-PFP PRECISION C8 Genesis EC C8 120A TSKgel ODS-100V TOSOH Bioscience Genesis C8 120A Bondclone C ChrometiSIL Phenyl Phenyl 1 ACE Phenyl ACE Phenyl Inertsil Ph-3 Genesis Phenyl Precision Phenyl 1 Bidentate C8 Microsolve ACE 5 CN TSKgel Super-Phenyl TOSOH Bioscience BetaBasic Phenyl 1 Prodigy Phenyl-3 XBridge Phenyl L56 Zorbax XDB-Phenyl ChrometiSIL C8 SH C8 SH Inertsil WP300 C8 PRECISION C8 ACE C4 L26 SepaxBio-C4 Sepax ACE 300 C8 HyPurity C4 L26 SepaxBio-C8 Sepax Discovery C8 TSKgel Octyl-80Ts TOSOH Bioscience ACE 5 C4-300 L26 Develosil C30-UG-5 L62 Discovery BIO Wide pore C18 Discovery BIO Wide pore C5 Alltima HP C8 Polaris C18-Ether Hypersil Beta Basic-8 Hypurity C8 Nucleosil C18 HD Polaris C8-Ether YMC Basic Hypersil GOLD C8 Acclaim 120 C8 BioBasic-4 Armor C18 3um Genesis EC C8 120A Bondclone C18

8 12. ChrometiSIL C8 SH C8 SH Precision C8-PE LiChrospher 60 RP-Select B TSKgel Super-Octyl TOSOH Bioscience ACE 5 CN Genesis AQ 120A SepaxHP-C18 Sepax Genesis C8 120A Polaris C18-A Curosil-PFP Nucelosil C8 HD Hypersil GOLD Betasil Phenyl-Hexyl Advantage Armor C18 120A Kromasil 100-5C8 Akzo Nobel Genesis C18 120A Genesis C4 300A L26 Alltima HP C18 Jupiter300 C5 Genesis C4 EC 120A L26 Xterra MS C18 Develosil ODS-UG-5 Symmetry 300 C4 L26 Cogent HPS C18 MicroSolv Inertsil WP300 C18 Jupiter300 C4 L26 Discovery C18 Xterra MS C8 ACE 5 C18 Discovery BIO Wide pore C8 Atlantis dc18 b Xterra Phenyl 1 XBridge C18 Zorbax Eclipse XDB-CN 0 Develosil ODS-HG-5 Hypersil Beta Basic-18 Chromegabond WR C8 ES Industries SepaxGP-C18 Sepax Unison UK-C18 Imtakt Atlantis T3 PRECISION C18 SepaxBioC18 Sepax ACE Phenyl Aqua C18 Restek Ultra C8 Restek Hypurity C18 XBridge Phenyl L56 Zorbax StableBond 300A C8 TSKgel Super-Phenyl TOSOH Bioscience Alltima C18 Hypersil Bio Basic-8 GraceSmart RP 18 5u Acclaim 120 C18 DeltaPak C18 300A 13. ChrometiSIL C18 ace-eps C18 ace-eps Eşdeğer kolonu bulunmamaktadır 14. ChrometiSIL C18 AQ C18 AQ Armor C18 3um Genesis C18 120A Cogent HPS C18 MicroSolv Unison UK-C18 Imtakt Nucleosil C18 HD Advantage Armor C18 120A Alltima HP C18 Xterra MS C18 ACE 5 C18 PRECISION C18 Alltima C18 Polaris C18-Ether SepaxGP-C18 Sepax ACE 300 C8 SepaxHP-C18 Sepax Develosil ODS-UG-5 Alltima HP C8 Inertsil WP300 C8 PRECISION C8 CAPCELL C18 M G Shiseido Chromolith RP18e Hypersil Beta Basic-18 Develosil C30-UG-5 L62 Hypersil GOLD TSKgel Super-Octyl TOSOH Bioscience Aqua C18 LiChrospher 60 RP-Select B

9 14. ChrometiSIL C18 AQ C18 AQ TSKgel Super-ODS TOSOH Bioscience XBridge C18 GROM-SIL 120 ODS-3 CP Grace-Grom Discovery C18 GROM-SIL 120 ODS-5 ST Grace-Grom Hypersil GOLD C8 Genesis C8 120A GraceSmart RP 18 5u Hichrom RPB HiChrom ACE C4 L26 Genesis AQ 120A Inertsil WP300 C18 Hypurity C18 Genesis EC C8 120A Acclaim 120 C18 Discovery C8 Develosil ODS-HG-5 TSKgel Octyl-80Ts TOSOH Bioscience Hypurity C8 Discovery BIO Wide pore C18 Precision C8-PE CAPCELL C18 SG120 Shiseido Hypersil Beta Basic-8 Acclaim 120 C8 ACE 5 C4-300 L26 COSMOSIL AR-II Nacalai Tesque YMC Basic OmniSpher 5 C18 SepaxBio-C8 Sepax Kromasil 100-5C8 Akzo Nobel Nucelosil C8 HD Denali (120A C18) Grace/Vydac BioBasic-4 HyPurity C4 L26 SepaxBio-C4 Sepax Bondclone C18 Atlantis dc18 b Zorbax Eclipse XDB-C18 Cadenza 5CL-C18 Imtakt /Silvertone Sciences Atlantis T3 SepaxBioC18 Sepax DeltaPak C18 300A Targa C18 Higgens Vydac Everest Grace/Vydac Xterra MS C8 Discovery BIO Wide pore C5 Symmetry 300 C18 Kromasil 100-5C18 Akzo Nobel Restek Ultra C8 Restek Onyx Monolithic C18 Polaris C18-A Hichrom RPB HiChrom Discovery BIO Wide pore C8 TSKgel ODS-80Ts TOSOH Bioscience Zorbax StableBond 80A C ChrometiSIL C18 H C18 H Polaris C18-Ether XBridge C18 ACE 300 C8 Discovery C18 Alltima HP C18 Hypersil Beta Basic-18 Develosil ODS-UG-5 Hypurity C18 Hypurity C8 Inertsil WP300 C18 Genesis C18 120A Develosil C30-UG-5 L62 Hypersil GOLD Develosil ODS-HG-5 Armor C18 3um ACE 5 C18 Alltima HP C8 Inertsil WP300 C8 ACE 5 C4-300 L26 BioBasic-4 TSKgel Super-Octyl TOSOH Bioscience Xterra MS C18 Discovery C8 SepaxBio-C8 Sepax Discovery BIO Wide pore C8 Discovery BIO Wide pore C18 SepaxBioC18 Sepax DeltaPak C18 300A PRECISION C8 TSKgel Super-ODS TOSOH Bioscience Chromegabond WR C8 ES Industries

10 15. ChrometiSIL C18 H C18 H Hypersil Beta Basic-8 Nucleosil C18 HD Hypersil GOLD C8 Cogent HPS C18 MicroSolv Symmetry 300 C18 Pursuit C18 HyPurity C4 L26 Hypersil Bio Basic-8 SepaxGP-C18 Sepax Polaris C18-A Unison UK-C18 Imtakt Jupiter300 C18 TSKgel Octyl-80Ts TOSOH Bioscience ACE C4 L26 Hichrom RPB HiChrom Hichrom RPB HiChrom SepaxBio-C4 Sepax Advantage Armor C18 120A Acclaim 120 C8 Hypersil Bio Basic-18 Chromolith RP18e PRECISION C18 LiChrospher 60 RP-Select B SepaxHP-C18 Sepax Acclaim300 C18 Genesis EC C8 120A Discovery BIO Wide pore C5 Genesis AQ 120A Polaris C8-Ether Aqua C18 OmniSpher 5 C18 Kromasil 100-5C8 CAPCELL C18 SG120 Akzo Nobel Shiseido Precision C8-PE TSKgel ODS-140HTP TOSOH Bioscience Denali (120A C18) Grace/Vydac Jupiter300 C4 L26 ACE 5 CN Bondclone C18 Acquity UPLC BEH C8 ACE 5 C ChrometiSIL C30 C30 L62 SynChropak RPP Eprogen HxSil C18 Hamilton Platinum EPS C ChrometiSIL C4 C4 L26 Genesis C4 EC 120A L26 Betasil Phenyl-Hexyl Bondclone C18 ACE C4 L26 Polaris C8-Ether Discovery BIO Wide pore C5 TSKgel Super-Phenyl TOSOH Bioscience Zorbax Eclipse XDB-CN 0 ACE 5 CN SepaxBio-C4 Sepax SepaxGP-Phenyl Sepax Zorbax StableBond 300A C3 L56 PRECISION C8 YMC Basic Precision C8-PE Genesis C4 300A L26 Curosil-PFP Inertsil WP300 C8 Zorbax XDB-Phenyl 1 TSKgel Octyl-80Ts TOSOH Bioscience HyPurity C4 L26 LiChrospher 60 RP-Select B ACE AQ ACE Phenyl Nucelosil C8 HD Genesis AQ 120A Precision Phenyl 1 Partisil C8 Xterra Phenyl 1 Genesis C8 120A Prevail C8 Nucleosil C18 HD SepaxBio-C8 Sepax Nucleodur Sphinx RP Genesis EC C8 120A ACE 5 C4-300 L26 Symmetry 300 C4 L26 Atlantis T3 Discovery C8

11 17. ChrometiSIL C4 C4 L26 Acclaim 120 C8 Atlantis dc18 b BetaMax Base Hypersil GOLD C8 Zorbax StableBond 300A C8 ACE Phenyl 1 ACE 300 C8 Hypersil Beta Basic-8 SepaxHP-C18 Sepax Discovery BIO Wide pore C18 Alltima HP C8 Develosil C30-UG-5 L62 Kromasil 100-5C8 Akzo Nobel HxSil C8 Hamilton Genesis Phenyl 1 XBridge Phenyl L ChrometiSIL C8 SH C8 SH ACE 5 C4-300 L26 Polaris C18-Ether ACE 300 C8 Develosil C30-UG-5 L62 BioBasic-4 SepaxBio-C8 Sepax ACE 5 CN Inertsil WP300 C8 Hypurity C8 Alltima HP C18 Hypersil GOLD LiChrospher 60 RP-Select B Alltima HP C8 PRECISION C8 ACE C4 L26 Inertsil WP300 C18 Armor C18 3um SepaxBioC18 Sepax Zorbax StableBond 300A C8 SepaxBio-C4 Sepax Discovery C8 HyPurity C4 L26 Nucleosil C18 HD Bondclone C18 Discovery BIO Wide pore C18 ACE Phenyl Polaris C18-A TSKgel Octyl-80Ts TOSOH Bioscience Hypersil Beta Basic-8 Polaris C8-Ether DeltaPak C18 300A Hypersil GOLD C8 Genesis C18 120A Curosil-PFP Discovery BIO Wide pore C8 Discovery BIO Wide pore C5 XBridge Phenyl L56 Discovery C18 XBridge C18 TSKgel Super-Octyl TOSOH Bioscience Genesis C4 300A L26 YMC Basic Develosil ODS-HG-5 Develosil ODS-UG-5 SepaxHP-C18 Sepax Hypurity C18 Hypersil Bio Basic-8 Cogent HPS C18 MicroSolv Unison UK-C18 Imtakt Xterra MS C18 Chromegabond WR C8 ES Industries Acclaim 120 C8 Hypersil Beta Basic-18 Genesis AQ 120A Advantage Armor C18 120A Genesis C8 120A Genesis EC C8 120A Precision C8-PE ACE 5 C18 TSKgel Super-Phenyl TOSOH Bioscience Platinum C8 Acclaim300 C18 Pursuit C18 Xterra Phenyl 1 Prevail C8 Aqua C18 Bidentate C8 Microsolve Betasil Phenyl-Hexyl Genesis C4 EC 120A L26 Nucelosil C8 HD

12 19. ChrometiSIL C18 H C18 H DeltaPak C18 300A SepaxBioC18 Sepax Genesis C18 300A Pursuit C18 Acclaim300 C18 Inertsil WP300 C18 Hypersil Bio Basic-18 Symmetry 300 C18 Vision C18 HL Alltima HP C18 Brava BDS C18 Hypurity C18 Hypersil Bio Basic-8 Hichrom RPB HiChrom ACE 5 C Jupiter300 C18 Polaris C18-Ether Discovery BIO Wide pore C8 XBridge C18 Develosil ODS-HG-5 BioBasic-4 Discovery C18 Zorbax StableBond 300A C18 Prosphere 300 C4 L26 Hypersil GOLD Chromegabond WR C8 ES Industries Develosil C30-UG-5 L62 Platinum C8 Hypersil Beta Basic-18 MicroBondapak C18 ACE 5 C4-300 L26 Selectosil C18 Acquity UPLC BEH C8 Hypersil ODS-2 ACE 300 C8 Chromegabond WR C18 ES Industries Hypurity C8 SepaxBio-C8 Sepax Develosil ODS-UG-5 Genesis C18 120A Hypersil BDS C18 ACE 5 C18 TSKgel Super-ODS TOSOH Bioscience Armor C18 3um Partisil ODS(3) 20. ChrometiSIL C18 ace-eps C18 ace-eps Discovery Amide C ChrometiSIL 60-5 C8 SH C8 SH Alltima HP C18 High Load Luna C18 Ultracarb ODS (30) J'Sphere M80 Synergi Fusion-RP Symmetry C18 Nucleodur Pyramid 22. ChrometiSIL 60-5-C18 H C18 H Ascentis Express C18 Halo-C18 Advanced Materials Technology Cadenza 5CL-C18 Imtakt /Silvertone Sciences OmniSpher 5 C18 COSMOSIL AR-II Nacalai Tesque Zorbax Extend C18 CAPCELL C18 SG120 Shiseido Wakosil II 5C18AR SGE Zorbax Eclipse XDB-C18 Zorbax Rx-18 Chromolith RP18e Denali (120A C18) Grace/Vydac 23. ChrometiSIL 60-5-C4 C4 L26 Alltima C18-WP Zorbax Rx-C8 Zorbax StableBond 80A C8 CAPCELL C18 A Q Shiseido GROM-Sil 120 ODS-4 HE Grace-Grom Gemini C18 110A GROM Saphir 110 C18 Grace-Grom YMC ODS-AQ Onyx Monolithic C8 GROM SAPHIR 110 C8 Grace-Grom Zorbax StableBond 80A C3 L56 GROM-SIL 120 Octyl-6 MB Grace-Grom TSKgel ODS-80Ts QA TOSOH Bioscience 24. ChrometiSIL 60-5-Phenyl Phenyl 1 MicroBondapak Phenyl ChrometiSIL CN Kromasil KR60-5CN Akzo Nobel 0 Xterra Phenyl 1 Curosil-PFP CN 0 Luna PFP(2) Genesis Phenyl ACE Phenyl 1

13 26. ChrometiSIL HyperSORB ODS ODS Exsil ODS Sphereclone ODS(2) SGE 27. ChrometiSIL SpheriBOND 80-5-ODS1 ODS1 Eşdeğer kolonu bulunmamaktadır 28. ChrometiSIL SpheriBOND 80-5-ODS2 ODS2 LiChrospher 100 RP-18 LiChrosorb RP-18 sil LC-PAH Exsil ODS SGE 29. ChrometiSIL C4 C4 L26 Zorbax StableBond 300A C8 Prevail C8 ACE 5 CN TSKgel Super-Phenyl TOSOH Bioscience Zorbax StableBond 300A C3 L56 Bondclone C18 ACE Phenyl HxSil C8 Hamilton Partisil C8 LiChrospher 60 RP-Select B SepaxGP-Phenyl Sepax Inertsil Ph-3 Precision Phenyl ACE Phenyl 1 Zorbax XDB-Phenyl ACE C4 L ChrometiSIL C30 EC C30 EC L62 Brava BDS C18 Selectosil C18 MicroBondapak C18 Partisil ODS(3) Prosphere 300 C4 L26 Nucleosil C18 Zorbax StableBond 300A C18 Genesis C18 300A Acclaim300 C18 DeltaPak C18 300A SepaxBioC18 Sepax Hypersil BDS C18 Hypersil GOLD aq ACE 5 C Pursuit C18 Hypersil Bio Basic-18 Platinum C8 Chromegabond WR C18 ES Industries Superspher 100 RP-18e KGaA Platinum C18 VisionHT C18 Vision C18 HL Hypersil ODS-2 Inertsil WP300 C18 Hypersil Elite Hypersil GOLD PFP Hichrom RPB HiChrom Nucleosil C8 31. ChrometiSIL C30 C30 L62 Alltima HP C18 EPS

14 L2 L3 L4 USP L Phase Listing Octadecyl silane chemically bonded to porous silica or ceramic micro-particles, 3 to 10 μm in diameter, or a monolithic rod. Eurosil-Bioselect 300 C18 Eurospher 100 C18 Hipak ODS AB Kromasil C18 EKA Nobel LiChrosorb RP 18 LiChrospher 100 RP 18 LiChrospher 100 RP 18e Nucleosil C18 Nucleosil C18 AB Partisil ODS Whatman Inc. Partisil ODS2 Whatman Inc. Partisil ODS3 Whatman Inc. ChrometiSIL C18 H ChrometiSIL C18 SH ChrometiSIL C18 AQ ChrometiSIL C18 AQ Plus ChrometiSIL C18 ace-eps ChrometiSIL EuroBond C18 ChrometiSIL Hypersorb ODS ChrometiSIL Spheribond ODS1 ChrometiSIL Spheribond ODS2 Sphere-Image ODS1 Sphere-Image ODS2 Superspher 100 RP 18 Superspher 100 RP 18e Techsphere ODS Grace Vydac Zorbax ODS Technologies Octadecyl silane chemically bonded to silica gel of a controlled surface porosity that has been bonded to a solid spherical core, 30 to 50 μm in diameter. Porous silica particles, 3 to 10 μm in diameter. Eurospher 100 Si Kromasil Si EKA Nobel LiChrosorb Si 100 LiChrosorb Si 60 LiChrospher Si-60 LiChrospher Si-100 Micra NPS-Silica Eprogen Nucleosil Silica Partisil Si Whatman Inc. ChrometiSIL SI Superspher 60 Si Superspher 100 Si Zorbax SIL Technologies Silica gel of controlled surface porosity bonded to a solid spherical core, 30 to 50 μm in diameter. L6 L8 L9 Strong cation-exchange packing-sulfonated fluorocarbon polymer coated on a solid spherical core, 30 to 50 μm in diameter. Octylsilane chemically bonded to totally porous silica particles, 3 to 10 μm in diameter. Eurospher 100 C8 HiPak C8 AB Kromasil C8 EKA Nobel LiChrosorb RP 8 LiChrosorb RP Select B LiChrospher 100 RP 8 LiChrospher 100 RP 8 e LiChrospher 60 RP select B Alltech Associates, Inc. Nucleosil C8 Nucleosil C8 ec Partisil CCS/C8 Whatman Inc. ChrometiSIL C8 SH ChrometiSIL C8 ace-eps Sphere-Image C8 Supersher 60 RP 8 Supersher 60 RP 8e Supersher 60 RP select B Techsphere Octyl Grace Vydac Zorbax C8 Alltech Associates, Inc. An essentially monomolecular layer of aminopropylsilane chemically bonded to totally porous silica gel support, 3 to 10 μm in diameter. Eurospher 100 NH2 Kromasil NH2 EKA Nobel LiChrosorb NH2 LiChrospher NH2 Nucleosil NH2 ChrometiSIL AMINO ChrometiSIL AMINO H ChrometiSIL AMINO E Sphere-Image Amino Techsphere Amino Grace Vydac Zorbax NH2 Technologies 10 μm irregular or spherical, totally porous silica gel having a chemically bonded, strongly acidic cation-exchange coating, 3 to 10 μm in diameter. Nucleosil SA Partisil SCX Whatman Inc. Sphere-Image SCX Zorbax SCX Technologies L5 Alumina of controlled surface porosity bonded to a solid spherical core, 30 to 50 μm in diameter.

15 0 1 2 Nitrile groups chemically bonded to porous silica particles, 3 to 10 μm in diameter. Eurospher 100 CN Kromasil 60 CN EKA Nobel LiChrosorb CN LiChrospher CN Nucleosil CN ChrometiSIL CN Sphere-Image CN Zorbax CN Technologies Phenyl groups chemically bonded to porous silica particles, 5 to 10 μm in diameter. Kromasil Phenyl EKA CHEMICALS Nucleosil Phenyl ChrometiSIL Phenyl Zorbax Phenyl Technologies A strong anion-exchange packing made by chemically bonding a quartenary amine to a solid silica spherical core, 30 to 50 μm in diameter Strong cation-exchange resin consisting of sulfonated crosslinked styrene-divinylbenzene copolymer in the hydrogen form, 7 to 11 μm in diameter. Carbex II (H+) VDS optilab Hamilton HC-75H Hamilton Co. Hamilton PRP-X200 Hamilton Co. Hamilton PRP-X300 Hamilton Co. Eurokat H Amino and cyano groups chemically bonded to porous silica particles, 3 to 10 μ in diameter. Partisil PAC Whatman Inc. Strong cation-exchange resin consisting of sulfonated crosslinked styrene-divinylbenzene copolymer in the calcium form, about 9 μm in diameter. Carbex II Ca VDS optilab Hamilton HC 40 Hamilton Co. Hamilton HC 75 Ca Hamilton Co. Eurokat Ca 3 4 Trimethylsilane chemically bonded to porous silica particles, 3 to 10 μm in diameter. Zorbax TMS Technologies Silica gel having a chemically bonded, strongly basic quaternary ammonium anion-exchange coating, 5 to 10 μm in diameter. Nucleosil SB Partisil SAX Whatman Inc. Sphere-Image SAX Zorbax SAX Technologies L20 L21 Dihydroxypropane groups chemically bonded to porous silica particles, 5 to 10 μm in diameter. Eurospher 100 Diol Kromasil Diol EKA CHEMICALS LiChrosorb Diol LiChrospher 100 Diol Nucleosil Diol ChrometiSIL Diol A rigid, spherical styrene-divinylbenzene copolymer, 5 to 10 μm in diameter. Hamilton PRP-1 Hamilton Co. 5 6 Hexylsilane chemically bonded to totally porous silica particles, 3 to 10 μm in diameter. ChrometiSIL Spheribond C6 Dimethylsilane chemically bonded to porous silica particles, 5 to 10 μm in diameter. Eurospher 100 C1 Lichrosorb RP2 ChrometiSIL C1 L22 L23 A cation-exchange resin made of porous polystyrene gel with sulfonic acid groups, about 10 μm in size. Hamilton PRP-X200 Hamilton Co. Hamilton PRP-X300 Hamilton Co. An anion-exchange resin made of porous polymethacrylate or polyacrylate gel with quartenary ammonium groups, about 10 μm in size. L24 A semi-rigid hydrophilic gel consisting of vinyl polymers with numerous hydroxyl groups on the matrix surface, 32 to 63 μm in diameter.

16 L25 Packing having the capacity to separate compounds with a molecular weight range from (as determined by polyethylene oxide), applied to neutral, anionic, and cationic water-soluble polymers. A polymethacrylate resin base, crosslinked with polyhydroxylated ether (surface contained some residual carboxyl functional groups) was found suitable. L35 L36 A zirconium-stabilized spherical silica packing with a hydrophilic (diol-type) molecular monolayer bonded phase having a pore size of 150 Å. A 3.5-dinitrobenzoyl derivatice of L-phenylglycine covalently bonded to 5 μm amminopropyl silica. L26 Butyl silane chemically bonded to totally porous silica particles, 3 to 10 μm in diameter. Eurosil Bioselect 300 C4 Eurospher 100 C4 Kromasil C4 EKA Nobel ChrometiSIL C4 L37 L38 Packing having the capacity to separate proteins by molecluar size over a range of to daltons. It is a polymethacrylate gel. A methacrylate-based size-exclusion packing for water soluble samples. L27 Porous silica particles, 30 to 50 μm in diameter. L39 A hydrophilic polyhydroxymethacrylate gel of totally porous spherical resin. L28 A multifunctional support, which consists of a high purity, 100 Å, spherical silica substrate that has been bonded with anionic exchanger, amine functionatily in addition to a conventional reversed phase C8 functionality. L40 Cellulose tris-3.5-dimethylphenylcarbamate coated porous silica particles, 5 μm to 20 μm in diameter. Eurocel 01 L29 Gamma alumina, reverse-phase, low carbon percentage by weight, alumina-based polybutadiene spherical particles, 5 μm in diameter with a pore volume of 80 Å. L41 Immobilized α 1-acid glycoprotein on spherical silica particles, 5 μm in diameter. L30 Ethyl silane chemically bonded to totally porous silica particles, 3 to 10 μm in diameter. L42 Octylsilane and octadecylsilane groups chemically bonded to porous silica particles, 5 μm in diameter. L31 L32 A hydroxide-selective strong anion-exchange resin-quaternary amine bonded on latex particles attached to a core of 8.5 μm macroporous particles having a pore size of 2000 Å and consisting of ethylvinylbenzene cross-linked with 55% divinylbenzene. A chiral ligand-exchange resin packing-l-proline copper complex covalently bonded to irregularly shaped silica particles, 5 to 10 μm in diameter. L43 L44 L45 Pentafluorophenyl groups chemically bonded to silica particles by a propyl spacer, 5 to 10 μm in diameter. A multifunctional support, which consists of a high purity, 60 Å, spherical silica substrate that has been bonded with a cationic exchanger, sulfonic acid functionality in addition to a conventional reversed phase C8 functionality. Beta cyclodextrin bonded to porous silica particles, 5 to 10 μm in diameter. L33 Packing having the capacity to separate dextrans by molecular size over a range of to daltons. It is spherical, silica-based, and processed to provide ph stability. L46 Polysterene/divinylbenzene substrate agglomerated with quaternary amine functionalized latex beads about 10 μm in diameter. L34 Strong cation-exchange resin consisting of sulfonated crosslinked styrene-divinylbenzene copolymer in the lead form, about 9 μm in diameter. Hamilton HC-75 Lead Form Hamilton Co. Eurokat Pb L47 L48 High capacity anion-exchange microporous substrate, fully functionalized with a trimethylamine group, 8 μm in diameter. Sulfonated, cross-linked polystyrene with an outer layer of submicron, porous, anion-exchange micro beads, 15 μm in diameter.

17 L49 A reversed-phase packing made by coating a thin layer of polybutadiene on to spherical porous zirconia particles, 3 to 10 μm in diameter. L50 Multifunction resin with reverse-phase retention and strong anionexchange functionalities. The resin consists of ethylvinylbenzene, 55% cross-linked with divinylbenzene copolymer, 3 to 15 μm in diameter, and a surface area not less than 350 m2 per g. Substrate is coated with quartenary ammonium functionalized latex particles consisting of styrene cross-linked with divinylbenzene. L51 Amylose tris-3.5-dimethylphenylcarbamate-coated, porous, spherical, silica particles, 5 to 10 μm in diameter. L52 A strong cation exchange resin made of porous silica with sulfopropyl groups, 5 to 10 μm in diameter. L53 Weak cation-exchange resin consisting of ethylvinylbenzene, 55% cross-linked with divinylbenzene copolymer, 3 to 15 μm diameter. Substrate is surface grafted with carboxylic acid and/or phosphoric acid functionalized monomers. Capacity not less than 500 μeq/column. L54 A size exclusion medium made of covalent bonding of dextran to highly cross-linked porous agarose beads, about 13 μm in L55 A strong cation exchange resin made of porous silica coated with polybutadiene-maleic acid copolymer, about 5 μm in diameter. L56... L62 Propyl silane chemically bonded to totally porous silica particles, 3 to 10 μm in diameter. C30 silane bonded phase on a fully porous spherical silica, 3 to 15 μm in diameter. ChrometiSIL C30 USP listing in preparation