PFF DISEASE EDUCATION WEBINAR SERIES. Welcome!
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1 PFF DISEASE EDUCATION WEBINAR SERIES Welcome!
2 ASK A DOC Q+A WITH PFF MEDICAL TEAM Harold Collard, MD PFF Senior Medical Advisor, Research Advisory Forum Gregory Cosgrove, MD PFF Chief Medical Officer David Lederer, MD, MS PFF Senior Medical Advisor, Education & Awareness Kevin Flaherty, MD, MS Steering Committee Chairman, PFF CCN & Patient Registry Ganesh Raghu, MD PFF Medical Advisory Board Member
3 PFF DISEASE EDUCATION WEBINAR SERIES Ask-a-Doc: 2015 Updated IPF Treatment Guidelines
4 DISCLAIMER We are providing medication information only. The information presented in this webinar should not be interpreted as medical advice or recommendations. Please discuss your medical condition with your health care provider before making any changes to your medical regimen.
5 ATS/ERS/JRS/ALAT IPF TREATMENT GUIDELINES Raghu G et al. Am J Respir Crit Care Med. 2015:192(2):
6 What is a clinical practice guideline & why do they exist?
7 WHAT IS A CLINICAL PRACTICE GUIDELINE? A Clinical Practice Guidelines is a formal document developed by a group of experts that makes recommendations for patient care These recommendations are based on an exhaustive and systematic review of the available evidence Doctors, insurance companies, and policymakers often follow the recommendations in these guidelines Many consider guidelines to be the standard of care
8 WHAT IS THE PURPOSE OF THIS GUIDELINE? The purpose of the ATS/ERS/JRS/ALAT Clinical Practice Guideline for IPF is to provide guidance to clinicians about the role of different treatment options in IPF Meant to empower clinicians to make appropriate clinical decisions for individual patients with IPF.
9 Who developed this guideline?
10 FOUR PROFESSIONAL MEDICAL SOCIETIES DEVELOPED THE GUIDELINE
11 ATS/ERS/JRS/ALAT IPF TREATMENT GUIDELINES Raghu G et al. Am J Respir Crit Care Med. 2015:192(2):
12 ATS/ERS/JRS/ALAT IPF TREATMENT GUIDELINES
13 What do the new guidelines recommend?
14 STRONG VS. CONDITIONAL RECOMMENDATIONS Raghu G et al. Am J Respir Crit Care Med. 2015:192(2):
15 ATS/ERS/JRS/ALAT 2015 IPF GUIDELINES: RECOMMENDED FOR USE IN IPF STRONG Recommendation CONDITIONAL Recommendation Nintedanib Pirfenidone Antacid therapy Raghu G et al. Am J Respir Crit Care Med. 2015:192(2):
16 ATS/ERS/JRS/ALAT 2015 IPF GUIDELINES: RECOMMENDED AGAINST USE IN IPF STRONG Recommendation CONDITIONAL Recommendation Anticoagulation (warfarin) Prednisone + azathioprine + NAC Ambrisentan Macitentan and bosentan Sildenafil NAC alone CONFIDENTIAL Raghu G et al. Am J Respir Crit Care Med. 2015:192(2):
17 WHAT HAS NOT BEEN ADDRESSED BY THESE GUIDELINES? Treatment recommendations for types of PF other than IPF Role of lung transplantation Treatment of pulmonary hypertension in folks with IPF Recommendations for different diagnostic approaches Role of ILD centers in the management of patients with PF
18 Q&A I am taking one of the medications that has a recommendation against use designation in the new guidelines. What should I do? Is pirfenidone available for use as an inhaled medicine? Will this help eliminate some of the side effects? I take anticoagulant medication for a different medical problem. Should I stop taking this?
19 Q&A There were no strong recommendations FOR any treatment. Does this mean that I shouldn t accept any treatments for my IPF? I saw that the guidelines addressed Triple therapy. What about prednisone without azathioprine or NAC?
20 ATS/ERS/JRS/ALAT 2011 IPF GUIDELINES: RECOMMENDED FOR USE IN IPF THAT STILL STAND STRONG Recommendation CONDITIONAL Recommendation Oxygen Lung Transplantation Pulmonary rehabilitation Steroids (prednisone) during an acute exacerbation CONFIDENTIAL Raghu G et al. Am J Respir Crit Care Med Mar 15;183(6):
21 ATS/ERS/JRS/ALAT 2011 IPF GUIDELINES: RECOMMENDED AGAINST USE IN IPF THAT STILL STAND STRONG Recommendation CONDITIONAL Recommendation Prednisone alone for outpatient Mechanical ventilation during an acute exacerbation Raghu G et al. Am J Respir Crit Care Med Mar 15;183(6):
22 PFF SUMMIT 2015 PFF Summit 2015 provides an unparralleled opportunity to meet with physicians, researchers, patients, caregivers, industry representatives, and members of the international PF community all in one setting. Register today!
23 Thank you.
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