KIVEX BIOTEC Ltd. CATALOGUE

Transcription

1 KIVEX BIOTEC Ltd. CATALOGUE 2014 LIFE SCIENCE

2 Illustration: Christina Laforce. LAFORCE ILLUSTRATION.

3 INDEX INTRODUCTION IVF WORKSTATIONS IVF INCUBATORS PRODUCTS G185 LONG TERM FLAT BED INCUBATOR IVF WORKSTATIONS 100 SERIES IVF WORKSTATION L234 CellTouch IVF WORKSTATION G IVF WORKSTATIONS L200 Series and L124 ICSI IVF WORKSTATIONS 400 SERIES WORKING PRINCIPLES, IVF WORKSTATIONS STANDARD AND OPTIONAL FEATURES, IVF WORKSTATIONS ERGONOMIC WORKPLACE QC DEVICES ANDROLOGY STATIONS ANTI VIBRATION TABLE WARMING PLATE / TROLLEY MINI INCUBATOR / BLOCK WARMER ACCESSORIES CONFIGURATION Innovation, design and manufacturing of IVF applications have been the core business of K-SYSTEMS for more than 27 years. The quality of K-SYSTEMS product are worldwide well known and our qualified technical support are based on trained local support. The idea behind K-SYSTEMS originates from the need of customers and we are continuously working on new development to fulfill these needs. We welcome you as a customer and hope this catalogue will be an inspiration to you. Best regards K-SYSTEMS Not valid for distribu on in the USA. 3

4 INTRODUCTION IVF Workstations - K-SYSTEMS the leading brand for 27 years. Today s workstation incorporates a number of features to meet the specialist's requirements of handling oocytes, sperm and embryos during human reproduction procedures. The Workstations have a unique design and are using the latest technology in air flow, air filtration and heat distribution to make the work zone usefull, efficient and clean. The well proven fan technology combined with the new designed electronic control system is supervising all workstation functions together with a full package of logging options. The ergonomic design, the number of various standard features and the low noise level makes the K-SYSTEMS IVF Workstations a primary choice in every IVF clinic. L 126 IVF Dual 4

5 INTRODUCTION IVF Incubators For more than 20 years K-SYSTEMS has been developing IVF incubators of various types. In the early 90 s the first flat bed incubator the Mini-CO₂ incubator G80 were introduced. Successively this platform has been developed into our present and more advanced model the Flat bed incubator CO₂/O₂ G185 incorporating more advanced features. Other specialized incubators have been introduced for transportation and ICSI procedures. G80 G185 Incubator Long Term Flat Bed Incubator CO2/O2 5

6 G185 LONG TERM FLAT BED INCUBATOR G185 The op mal incubator solu on for embryos and clinicians with G185 Stable ph levels are achieved through the combina on of K-Systems hea ng and gas control system The G185 ensures safe and careful incuba on, giving the best condi ons for op mal embryo development. Stable ph levels and osmolality of the medium during culture is ensured. All cri cal parametres are monitored and controlled chamber by chamber, which ensures: Stable ph Stable hea ng Stable gas levels The chamber-by-chamber temperature control combined with the direct heat from the hea ng plates to the culture dishes ensures op mal temperature condi ons at all mes. The special flow system ensures constant grade A gas in each chamber. Each individual chamber recovers in less than 2 minutes. Chambers 100% CO₂ 100% N₂ Gas Miing Chamber Inlet Manifold HEPA Filter VOC Filter UV Light Working with an oil overlay in the G185 will delay gas diffusion and help stabilize the PH levels and osmolality of the medium during culture. The integrated gas miing system gives you the op on to mi CO₂ and O₂ to your specifica ons. Before entering the gas miing chamber, the gas circulates through mul ple filters: High efficency par cle filter to remove airborne par cles UV light to eliminate organic microbes VOC filter to remove organic compounds. Fewer stress factors for the embryos The G185 is designed to minimize the stress factors to the embryos. The G185 is a non-humid incubator, which strongly minimizes the risk of fungal growth inside the incubator and makes it easier to clean. The use of the oil overlay helps separate the medium from the atmosphere and any airborne par cles or pathogens. The incubator includes 10 individual incuba on chambers to ensure minimal metabolic stress and risk of cross contamina on for the embryos. 6

7 G185 LONG TERM FLAT BED INCUBATOR Everyday embryo culture made effec ve, easy and reliable With the best embryo condi ons combined with an intui ve design and low running costs the G185 is the ideal work horse in a busy clinic Due to its design the G185 will accommodate up to 10 pa ents and help you save significant space in your clinic The unit can be connected to CO2 alone or you can add N2 to reduce the oygen level. The G185 uses pure CO₂ and N₂ gas. Combined with the limited gas intake when opening a chamber, ensures low annual running costs. G185 Effec ve monitoring and quality control built in Through detailed monitoring and alarm systems you can react quickly and effec vely to changing condi ons in the incubator The G185 is equipped with etensive alarm and monitoring op ons. This assures that condi ons in the incubator are constantly monitored and you can react quickly if condi ons changes. All versions include a data logging package automa cally monitor and log all vital parameters. Temperature control of each zones CO₂ & O₂ gas concentra on CO₂ & O₂ gas flow and pressure Daily averages for all parameters Alarm record register signal func on when an alarm is ac vated All data are logged as ecel files. 3 G185's can be monitored from one PC. 7

8 G185 LONG TERM FLAT BED INCUBATOR The G185 SensorTech. G185 PH measuring is possible in the G185 SensorTech version by using an eternal system based on infrared monitoring, which unlike other systems ensure effec ve and highly accurate long term measurements without the need for cleaning. The system has a resolu on of 0.01 ph and an accuracy of 0.03 ph. The G185 SensorTech is designed to allow for eternal monitoring of both temperature and CO₂ to ensure con nuous and effec ve quality control. + - ph Online Sensor Resolu on 0.01 ph Accuracy ph Range ph Pre-calibrated Sensor Dish for Non-contact Measurement Save space with the G185 and the K-Systems Stacking System Monitor is Op onal The Stacking system ensures space saving in the clinic and is designed with room for a computer at the bo om connec ng to all three systems, allowing for central monitoring on one screen. Sliding shelves with so closure func on Cooling system for heat removal Tray system for tubes and cable Internal electrical sockets Internal power outlet for three incubators Overall dimensions (WDH) mm Weight: 100 kg. 8

9 G185 LONG TERM FLAT BED INCUBATOR Clinical Trials and Valida ons of G185. Installed: 20 Incubators G185 Installed: 23 Incubators G185 Installed: 10 Incubators G185 Installed: 7 Incubators G185 Read all the G185 Clinical Surveys at 9

10 IVF WORKSTATIONS IVF Workstations L124 IVF and L125 IVF L 124 & L 125 L 126 IVF L 125 IVF Overall dimensions (WDH): L125 IVF: mm / " L124 IVF: mm / " Configuration see page 28 Standard features: Stainless Steel Table Top Integrated Alu Heat System Mounting Assembly for most Stereo Microscopes Microscope Light Opening with Heated Glass Ø90 Integrated Gassing and Humidification System Eye Draught Protection 2 Electrical Outlets inside the cabinet Support Stand Options: Built-in Monitor Heated Pass Through Tunnel Incorporated Micro-Incubator Etra Large Heated Area Full Heated Area Light Source UV-Light Support Stand with Electrical Adjustable Height Support Stand with Shelf L124 IVF - Order Code: L125 IVF - Order Code: IVF Workstation L126 IVF Standard features: Stainless Steel Table Top Integrated Alu Heat System Mounting Assembly for most Stereo Microscopes Microscope Light Opening with Heated Glass Ø90 Integrated Gassing and Humidification System Eye Draught Protection 2 Electrical Outlets inside the cabinet Support Stand Overall dimensions (WDH): mm / " Configuration see page 28 Options: Built-in Monitor Heated Pass Through Tunnel Incorporated Micro-Incubator Etra Large Heated Area Full Heated Area Light Source UV-Light Support Stand with Electrical Adjustable Height Support Stand with Shelf L126 IVF - Order Code: Standard Features 100 Series (Not L124 ICSI) 2 Electrical outlets inside the cabinet Heated Glass Stage Ø90 Gassing and Humidification System Control Panel Warmed Area Table Top Eye Draught Protection 10

11 IVF WORKSTATIONS IVF Workstation L126 Dual Standard features: Stainless Steel Table Top Integrated Alu Heat System Mounting Assembly for most Stereo Microscopes 2 Microscope Light Opening with Heated Glass Ø90 2 Integrated Gassing and Humidification System 2 Eye Draught Protection 2 Electrical Outlets inside the cabinet Support Stand L 126 Dual Options: Built-in Monitor Heated Pass Through Tunnel Incorporated Micro-Incubator Light Source UV-Light Support Stand with Electrical Adjustable Height Support Stand with Shelf L126 Dual - Order Code: Overall dimensions (WDH): mm / " Configuration see page 28 A dual worksta on offers the poten al to simultaneously set up a perfect rota on system / organize division of work and keep the workflow of individuals undisturbed. E.g.: in the morning: one technician checks the oocytes for fer liza on or scores the embryos and transfers them to new dishes. Meanwhile, another technician can prepare the dishes for cryopreserva on and runs the cells/embryos to be cryopreserved through the series of cryoprotectants. IVF Workstation L126 MP Standard features: Stainless Steel Table Top Integrated Alu Heat System Mounting Assembly for most Stereo Microscopes Mounting Assembly for most Inverted Microscopes Integrated Anti-Vibration Table Microscope Light Opening with Heated Glass Ø90 Integrated Gassing and Humidification System Eye Draught Protection 2 Electrical Outlets inside the cabinet Support Stand L 126 MP Options: Built-in Monitor Heated Pass Through Tunnel Incorporated Micro-Incubator Light Source UV-Light L126 MP - Order Code: Optional Features 100 Series (Not L124 ICSI) Overall dimensions (WDH): mm / " Configuration see page 28 The right side is for moun ng of a stereomicroscope and le side is dedicated to an inverted microscope for performing ICSI / IMSI in clean air. The MP version is cost and space saving by integra ng the An -Vibra on facili es into the worksta on. The An -Vibra on Table eliminates vibra ons from reaching the microscope pla orm and dampening unavoidable vibra ons in the shortest possible me. Heated Pass Through Tunnel Build-in Monitor Incorporated Micro-Incubator Light Source Electrical Adjustable Height 11

12 IVF WORKSTATIONS IVF Workstation Class II L234 CellTouch L 234 IVF Standard features: Touch Screen with quick overview of all functions Stainless Steel Table Top Integrated Alu Heat System Mounting Assembly for most Stereo Microscopes Microscope Light Opening with Heated Glass Ø90 Integrated Gassing and Humidification System Electrical Outlet inside the cabinet Support Stand Options: Gassing and Humidification System (GH01) Built-in Monitor Light Source Support Stand with Electrical Adjustable Height Support Stand with Shelf L234 IVF - Order Code: Overall dimensions (WDH): mm / " Configuration see page 29 A scratch-free and VOC free stainless steel table top New silent Air Flow Technique Improved hea ng system with edge correc on 5 hea ng zones for detailed control and fast accurate calibra on New improved Air Flow. As a Class II cabinet the air flow pa ern complient with EN Average flow rate above 0.30 m/s. 90 mm clear glass heated stage with integrated temperature indicator. Easy cleaning of folding down Trough Sliding window with Ocular Bag Easy to service with minimum disturbance in your lab Low Noise Level Monitor your heat zones Plan your week and save energy Access to present and historical user interac ons It's not just a touchscreen Monitor your heat zones Follow the trend and open the log Quickly respond to problems (alarms) Energy Saving Keep your unit healthy - never forget maintenance Avoid unauthorized changes to setup parameters Record of changes to se ngs Effec ve monitoring and quality control build in Avoid unauthorized changes to setup parameters Quick respond to problems (alarms) Standard Features 200 Series Electrical outlets inside the cabinet Heated Glass Stage Ø90 Gassing and Humidification System Control Panel Warmed Area Table Top 12

13 IVF WORKSTATIONS IVF Work Chamber G603 Minimice the stress on embryos with the G603. The G603 combines the characterics of a K-Systems worksta on with an incubator like environment making it ideal for: G603 The aspira on room for retrieval processes In larger IVF clinics for transport between the Aspira on room and the Embryo lab Work procedures in the Embryo lab Overall dimensions (WDH): mm Weight: 112 kg. Version with special front (op on) Features: The integrated gas miing system mies the CO₂ and O₂ to your preferred level of miture Miing range for CO₂: 2-10%, for O₂: 2-20% The re-circulated, humidified and warmed gas combined with the Alu Heat system assures a stable temperature in the en re Work area The re-circulated gas has a Grade A quality achieved by circula on through a HEPA filter, a VOC filter, and a closed UV light chamber Air entering through the side ports during opening is absorbed by an upward suc on Easily changeable cuffs Easily access through side doors Can be prepared for a number of microscopes Data logging and alarm so ware included Outlets for USB, HDMI Sample ports for eternal valida on of CO₂ and O₂ Humidity up to 60% Ergonomic design: Electrical adjustable height, range: cm. Castors to be mounted So Support pads for arm rest. Op onal: Front with etra large access dors. Access doors with integrated easily changeable cuffs. Light Source G603 IVF - Order Code: Standard Features 600 Series Heated Glass Stage Ø90 Humidifier Control Panel Warmed Area Table Top Occular Bag 13

14 IVF WORKSTATIONS L 226 Dual IVF Workstations Class II L226 IVF and L226 Dual Standard features: Stainless Steel Table Top Integrated Alu Heat System Mounting Assembly for most Stereo Microscopes Microscope Light Opening with Heated Glass Ø90 Integrated Gassing and Humidification System 2 Electrical Outlets inside the cabinet Support Stand Options: Gassing and Humidification System (GH01) Built-in Monitor Light Source UV-Light Support Stand with Electrical Adjustable Height Support Stand with Shelf Overall dimensions (WDH): L 226 IVF and 226 Dual: mm / " Configuration see page 29 L226 IVF - Order Code: L226 Dual - Order Code: IVF Workstation L124 ICSI L 124 ICSI Standard features: Stainless Steel Table Top Mounting Assembly for most Inverted Microscopes Fied Front Window 2 Electrical Outlets inside the cabinet Support Stand Options: UV-Light L124 ICSI - Order Code: Designed as one workplace and prepared for an inverted microscope - for performing ICSI / IMSI under a laminar flow. The An -Vibra on table is integrated, working independently of the worksta on. Overall dimensions (WDH): mm / " Configuration see page 28 Standard Features 200 Series Electrical outlets inside the cabinet Heated Glass Stage Ø90 Gassing and Humidification System Control Panel Warmed Area Table Top 14

15 IVF WORKSTATIONS IVF Workstations L423 and L424 Standard features: Stainless Steel Table Top Integrated Alu Heat System Mounting Assembly for a range of Stereo Microscopes Microscope Light Opening with Glass Ø40 Fied Front Window Electrical Outlet inside the cabinet Support Stand L 423 & 424 Options: Gassing and Humidification System Light Source Microscope Light Opening with Heated Glass Ø90 UV-Light Overall dimensions (WDH): L 423 IVF: mm / " L424 IVF: mm / " Configuration see page 31 L423 IVF - Order Code: L424 IVF - Order Code: IVF Workstations L426 and L426 Dual Standard features: Stainless Steel Table Top Integrated Alu Heat System Mounting Assembly for a range of Stereo Microscopes Microscope Light Opening with Glass Ø40 Fied Front Window Electrical Outlet inside the cabinet Support Stand L 426 Dual Options: Etra Large Heated Area Gassing and Humidification System Light Source Microscope Light Opening with Heated Glass Ø90 UV-Light Overall dimensions (WDH): L426 IVF: mm / " L426 Dual: mm / " Configuration see page 31 L426 IVF - Order Code: L426 Dual - Order Code: Standard Features 400 Series Electrical outlets inside the cabinet Control Panel Warmed Area Table Top Fied Front Window 15

16 IVF WORKSTATIONS Working Principles and IVF Workstation Models The filtration system of IVF Workstations is designed to provide clean air in the work area. Each model of Workstations has a blower plenum designed to minimize air turbulences and eliminate dead air zones. The air flow pattern of the K-SYSTEMS workstations meets the relevant standards such as ISO or EN for Class II cabinets. The 100 Series are based on well proven fan technology in combination with a newly designed electronic control system. This allows for a low noise level, a balanced, vibration free and uniform air distribution giving a longer filter life. The air quality is compliant to ISO and adjusted to secure a safe and particle free work area. The 400 series are the entry model, with less standard features and are considered our low cost model. L 126 MP 16

17 IVF WORKSTATIONS The 200 series is mainly for IVF clinics where a potential hazard is involved when working with biological material from high risk patients. As a Class II cabinet the air flow pattern is complying to EN with a average down flow rate of 0.36 m/s (required 0.25). For detailed information see technical product information. Filtered air Non-filtered air The 200 series gives protection to both your samples and to the operator. Please be aware, once a stereo microscope or other large objects has been installed, the air flow becomes disrupted and the protection factor may be reduced. The 600 Series offers an ideal solution for Oocyte screening, Fertilization, Cleavage check and Embryo/blastocyst transfer in a humidified and O₂/CO₂ controlled environment. UV Light Pressurized Gas miing chamber Air Hea ng VOC Filter 100% O₂ 100% N₂ HEPA Filter Work Area with air circula on Humidifica on tray G603 Grade A Quality gas and air is maintained. 17

18 IVF WORKSTATIONS Standard and optional features The K-SYSTEMS Workstations incorporates a number of features to ensure operators comfort and ergonomics. The front window with the integrated Eye Draught Protection improves the comfort when operating the stereo microscope. The smooth running and stable height adjustable system(optional) gives the operator the optimum working conditions, even when standing. The ergonomic shaped arm rests is designed for maimum operator comfort. The clear side windows, the glare free rear wall and the adjustable illumination of the work area are aid comfort in a daily work routine. Standard Features Fied Window 400 Series Sliding Window 200 Series Eye Draught Protec. 100 Series Solid Stand Electrical Outlet Control Panel Heated Table Top Heated Glass Stage 100 and 200 Series Gassing and Humidifica on 100 Series Op onal Features Gassing and Humidifica on GH and 400 Series El. Adjustable 100 and 200 Series Stand w. Shelf 100 and 200 Series Light Source Tunnel 100 Series Incubator 100 Series Monitor 100 and 200 Series The well proven Alu Heat system provides the most precise temperature control. The heat distribution is controlled in up to 5 different heating zones, and with the new Edge Enhancement, system cold edges are minimized when strong air flow is used. Calibration of each heating zone can be seen and adjusted at the main control panel. Each heating zone is individual calibrated with specialized software to monitor each zone and ensure a uniform heat distribution. The unique design of the Alu Heat systems ensures ecellent heat transfer to the samples and avoidance of temperature overshoot. The unit temperature is constantly being displayed on the front panel of the work area. The 90 millimeter clear glass heated light stage has integrated temperature indicator. The indicator is microprocessor controlled and co-ordinates all heating zones. Zone 1 Zone 1 Zone 2 Zone 4 5 Zone 3 18

19 IVF WORKSTATIONS Microscope, light sources and microscope stages. Practically any type of stereo microscope may be built into the table plate. The microscope stages are individually mounted for each type of stereo microscope. For installation of inverted microscope, a recess in the rear wall allows for ease of positioning. Anti-vibration mounts are available to optimize working conditions for the inverted microscope. The gas miture is humidified by means of a gas washing system with double digital flow meters and regulators for CO₂ mounted in the rear wall(the 100 series). To allow for maimum moisture, the surface of the gas washers is heated to 37 C and the humidified gas is etruded through nozzles in the table plate. In the 200 and the 400 series are used stand alone humidifiers with digital flow meters to adjust the CO₂ flow. The transmitted light source(optional) for the stereo microscope are located under the stainless steel table plate. Light and heated glass are controlled by a microprocessor. Used in L 100 Series Used in L 200/ L 400 Series The light source features two condenser lenses, and has a bi-directional mirror and adjustment for focus and light intensity to ensure precise illumination and optional color filters. The light source can provide virtual dark field illumination The fully sealed 19" high resolution monitor (optional) An ecellent tool for viewing, training and education. The viewing panel of glas is designed to non disturbance of the air flow and easy to clean. The monitor supports most of the signals coming from modern digital cameras and supports DVI, HDMI as well as analog signals. Connect the monitor to your eternal PC and you bring the pictures right into your office or meeting room. Reduced air speed flow, auto start, auto stop are all standard features in the micro-processor controlled environment. Reduced air flow maintain the cabinets work area whilst not in operational mode. Auto start, auto stop is simply programmed via the operational panel in front of the cabinet and can easily be adjusted. 19

20 ERGONOMIC WORKPLACE Support stands for K-SYSTEMS IVF workstations STANDS Ergonomic eleva on support stand for your IVF Worksta on. The new developed K-SYSTEMS Support Stand with Electrical Adjustable Height will offer you maimum comfort, either si ng or standing Features: Adjust the work height eactly to your need with this smooth non-step eleva on system A simpel touch at the bu om will adjust precisely the work height in the range of: mm Stability and safety developed in accordance with EN assures high stability also at highest eleva on level The use of high quality components ensures the highest level of usability Compa ble with eis ng 100 and 200 series worksta ons (ecept MP and ICSI versions) Support stand with shelf for computer for your IVF Workstation Integra on of the computer in the support stand of your Worksta on will offer you several advantages. 5 openings for cables More easy cleaning under and around the Worksta on Cables and fi ngs becomes integrated part of the support stand No more loose hanging cables All details prepared to ensure a high level of usability Safety feet ensure high stability and safety 20

21 QC DEVICES Thermometer - for calibra ng flat bed incubators and worksta ons The F100 precision thermometer is a resi ve type thermometer with an accuracy of ±0,02 compared to common used thermo couple types with accuracy of ±0,1. The resolu on of the F100 is 0,001 C needed for a correct calibra on of i.e. your flat bed incubator. System accuracies be er than C over the full opera ng range. Stability: <0.005 C per year. Dual inputs measuring PRT's & thermistors single or differen al measurement. Sta s cal analysis- average, ma/min and standard devia on. Internal logging, so ware and USB communica on. K-Systems precision Gas Analyser The high precision gas analyser uses two analysing sensors: One electrochemical (galvanic fuel cell) sensor with a 4-5 years life me and a dual beam NDIR CO2 sensor Sensors are well proven and reliable for your IVF equipment. Sample Pump - Miniature diaphragm type with ~5cc/sec flow Size mm Weight Kg Standards - CE, RoHS, Technical specifica ons: F100 Accuracy F100 only: ±0.02 C (±20mK) Resolu on C Stability Long term: typically <0.002Ω per year (<0.005 C for Pt100) Data entry format ITS90 and CvD for calibrated probes: or EN for un-calibrated probes Probe types Pt100 and Pt25 resistance thermometers plus NTC thermistors. Cable length typically 2M Thermometer input2 5 pin industrial DIN socket with screw lock to connec ng plug, accep ng both normal and SMART probes Display Backlit LCD Communica ons USB interface Opera ng condi ons Full specifica on range: +15 C to +25 C Full opera ng range: 0 C to +40 C <80%RH non-condensing Power Nickel-Metal Hydride (Ni-MH) rechargeable ba ery Charging socket built-in Low ba ery indicator Dimensions (LDXW) mm nominal Weight 500 g (1.1 lbs) Order Code Calibrated probe for incubators and heated stages Order Code G185 Test Lid for the F Order Code thermometer F Technical specifica ons Sensor type O2: Proprietary Electrochemical CO2: Solid-state Infrared Epected Life me: O2: 4 years CO2: Theore cally unlimited Measurement Ranges: O2: 0 to 100% CO2: 0-20% Oygen Sensi vity: 0.1% O2 O2 Resolu on: 0.1% O2 CO2 Accuracy± 1% of reading or ± 0.1% CO2 (whichever is greater) Calibra on Frequency: O2: Weekly; set with room air set to 20.9% O2. CO2: Every 18 months; calibra on gas recommended. CO2 Calibra on Controls: Poten ometer SPAN adjustment for CO2. Minimum Detec on Limit: O2: 0.1% CO2: 0.01% Not calibrated. 21

22 ANDROLOGY STATIONS ANDROLOGY Andrology Sta on Suitable for the Andrology room and in the same elegant design as the K-SYSTEMS IVF worksta ons. These Andrology Sta ons features: Control panel integrated in the table plate Ergonomically shaped arm rest at the table plate Low noise level Side windows for operators comfort Op onal: Heated surface to the table top Andrology Sta ons based on the L100 & L400 series: L124 (120 cm) - Order Code: L125 (150 cm) - Order Code: L126 (180 cm) - Order Code: L423 (90 cm) - Order Code: L424 (120 cm) - Order Code: L426 (180 cm) - Order Code: Class II Cabinets L200 Series: L224 (120 cm) - Order Code: L226 (180 cm) - Order Code: Configura on see page 30 CO₂/O₂ Humidifier for the 200 and the 400 Series GH01 In combina on with glass incubator hoods, the humidifier is usefull for preserving culture dishes during oocyte or embroy handling. Features: Adjustable flow rate with integrated digital flow meter. Range 0-50 L/h. Hea ng element for hea ng the water to C Gas washer bo le with diffuser Removable water bo le for cleaning or autoclaving. To be connected to pre-mied gas. GH01 - Order Code: Overall dimensions (WDH): mm Weight: 0.92 kg. 22

23 ANTI VIBRATION TABLE The IVF An Vibra on Table AV1 The An Vibra on Table AV1 is able to handle heavy and less heavy inverted microscopes. The Spring system can be tuned to the op mal resonance frequency. The system is well damped, using coloumb-fric on-damping. Working range kg. AV1 Overall dimensions (WDH): mm / " Weight: 100 kg. - designed and developed to meet the requirements of ICSI procedures Useful accessories G85 Mini Incubator. Elimina ng vibra ons and ensuring a fast dampening effect is essen al when working with inverted microscopes. The AV1 features: A mass and a s ff support spring system to ensure fast dampening An equilibrated and isolated pla orm for the inverted microscope Roomy workspace around the inverted microscope for micromanipula ng systems Space for mini incubator Stainless steel shelf for accessories Monitor on a fleible arm (op onal) Work with microscopes from kg. AV1 - Order Code:

24 WARMING PLATE / TROLLEY Warming plate T47 in elegant design T47 In need of etra heated work space, this warming plate is ideal to maintain the right temperature in species (warming blocks for tubes or dishes), the warming plate features: easy to read temperature display a control panel for adjus ng the temperature a chemical resistant and easy to clean, hardened doubleanodized surface Overall dimensions (WDH): mm / 19180,4" Weight: 2.66 kg. T47 - Order Code: Trolley with warmed table top designed for the aspira on room R65 The easily cleaned trolley has a smooth surface ready to be covered with sterile ssues, and provides an ideal space for media and follicular fluid during oocyte retrieval. The mobile trolley features: Alu heated table top with control panel and digital reading of temperature Heated drawer. Shelf for storage Castors, 2 with brakes R65 - Order Code: Overall dimensions (WDH): mm / " Weight: 25 kg. Warming Blocks B16F / B16N B24 B25 B26 B28 B29 24

25 INCUBATORS CO₂ Mini Incubator G85 - ideal for ICSI procedures or to be used inside a Worksta on To op mize culture condi ons and to avoid severe fluctua ons in temperature during ICSI or other me consuming procedures, the Mini Incubator is offering a good solu on for temporary storing of the culture dishes. G85 The Mini Incubator features: digital flow meter for adjus ng flow rate of the CO₂ humidified environment of the stored culture dishes. Heated lids to avoid condensa on Flushing and purge func on for fast recovery in the chambers Two chambers with space for 4 culture dishes. Opera on by pre-mied gas. Overall dimensions (WDH): mm Weight: 5.4 kg. G85 - Order Code: Block Warmer for hea ng samples in test tubes, G73 - ideal for all tubes requiring a stable heated environment. The block warmer is designed for storing round and rectangular warming blocks, is easy to clean and suitable for various purposes such as holding tubes for follicular fluids a er retrieval etc. G73 Features: Control panel with digital readout Integrated hea ng element with PID controller Temperature accuracy ± 0.20 C. Compa ble with the following warming blocks. See net page G73 - Order Code: Overall dimensions (WDH): mm / 873,5" Weight: 1.66 kg. Warming Blocks B06 B08 B01 B03 B04 B30 25

26 ACCESSORIES Warming Blocks To maintain and preserve the temperature in the media during opera on, a wide range of warming blocks for dishes, tubes, and syringes are available. The warming blocks can be used either in your worksta on, in the incubators, on warming plates, block warmer, under incubator hoods or other suitable places. For tubes Order code: For culture dishes Order code: B01 Round block, holds 7 tubes of 17 mm Ø Falcon /NUNC B16F Holds 2 culture dishes Falcon B03 Round block, holds 12 tubes of 12 mm Ø Falcon B16N Holds 2 culture dishes NUNC / B04 Round block, holds 4 tubes of 25 ml 23.5 mm Ø B24 Holds 1 center well dish Falcon B06 Rectangular block, holds 12 tubes of 12 mm Ø Falcon /NUNC B25 Holds 1 60 mm Ø culture dish Falcon / and NUNC / B08 Rectangular block for portable, holds 10 tubes of 17 mm Ø Falcon B26 Holds 1 4-well dish Falcon B09 Block for swim-up test, 45 angle, holds 2 centrifuge tubes of 17 mm Ø Falcon B28 Holds 1 4-well dish NUNC / B29 Holds 1 5-well dish MiniTübe 19021/ Blocks for use with the G85 Blocks for use with the G73 B16F - B16N - B24 B25 - B28 - B29 B01 - B03 - B04 - B06 B08 - B40 - B41 - B43 26

27 ACCESSORIES For syringes For media flasks B30 Holds 5 flushing syringes of 20 ml / 22.5 mm Ø B35 Holds 5 flushing syringes of 10 ml / 18 mm Ø Order code Order code: Standard Accessories SA101 Content: B01, B09, B25, B28, B40, B41, G101, G102, G103 Recommended for L124IVF, L125IVF, L126IVF, L126MP Order Code Standard Accessories SA102 Content: 2B01, 1B09, 1B25, 1B28, 1B40, 1B41, 2G101, 1G102, 2G103 Recommended for L126Dual Order Code Standard Accessories - SA103 Content: B01, B09, B25, B28, B40, G01, G02, G03 Recommended for L224IVF, L226IVF Order Code B40 Holds 1 IVF media flask of 125 ml Standard Accessories - SA104 Content: 2B01, 1B09, B25, B28,B40, B41, 2G01, 2G02, 2G03 Recommended for L226Dual Order Code B41 Holds 2 media flasks of 60 ml B43 Holds 4 media flasks of 10 ml Incubator Glass Hoods A hood to protect the media from being cooled by any air flow. By using the glass incubator hood the media in the culture dishes are con nuously flushed in order to maintain the ph and at the same me avoid changes in osmolality. In the 100 series you will only need to place the incubator hoods over the nozzles in the table top. In the series 400 and the 200 the incubator hood is connected to the stand alone humidifica on and gassing unit (GH01) with the use of a silicon tube. Glass incubator hoods 100 series Order code Glass incubator hoods 200 & 400 series Order code: G101 For gassing culture dishes Ø 140 mm height 75 mm G01 For gassing culture dishes Ø 140 mm height 75 mm G102 For gassing media and sperm samples incl. holder for tubes Ø 130 mm height 130 mm G02 For gassing media and sperm samples incl. holder for tubes Ø 130 mm height 130 mm G103 For gassing culture dishes Ø 140 mm height 25 mm G03 For gassing culture dishes Ø 140 mm height 25 mm

28 CONFIGURATION L100 IVF Standard Features Ver cal Laminar Flow V.O.C Pre-filter & HEPA FILTRATION AluHeat technology Prepara on for a Stereomicroscope Right Side Prepara on for a Stereomicroscope Le Side Prepara on for 2 Stereomicroscopes (Right & Le posi on) Integrated Internal Humidifica on System Hea ng surface with 3 Thermal Sensors per working area (6 thermal Sensors in L126 Dual) Incorporated K-Systems Heated Glass Stage 2 Electrical socket Counter for usage hours of the fans Two speed for the fan ( High & Low) HEPA Filter Alarm indica ng HEPA filter need to be checked Possiblity of switching off the le heated surface in an L126 Dual Programming for an automac c start up of the worksta on Control of the Light Intensity of the K-systems light source from the control panel An Vibra on Table (AV5) prepared for one inverted microscope L100 IVF Op onal Features Eternal Humidifica on System Gh01 Etra Large Heated Areal Incorporated UV Light Adjustable Height Incorpora on of a Light Source LS12 / Ls11 Integrated Incubator Integrated Monitor Integrated Tunnel Integrated Incubator + Monitor L124 IVF L124 ICSI L125 IVF L126 IVF L126 Dual L126 MP Standard Op onal Not applicable 28

29 CONFIGURATION L200 IVF Standard Features Ver cal Laminar Flow Double HEPA FILTRATION AluHeat technology Prepara on for a Stereomicroscope Right Side Prepara on for a Stereomicroscope Le Side Prepara on for 2 Stereomicroscopes (right & Le posi on) Hea ng surface with 4 Thermal Sensors per working area Hea ng surface with 5 Thermal Sensors per working area Incorporated K-Systems Heated Glass Stage Ø90 Integrated camera adapter Touch Screen, Android system. Counter for usage hours of the fans in the Menu System HEPA Filter Alarm indica ng HEPA filter need to be checked Programming for an automac c start up of the worksta on Air Flow Sensor Control of the Light Intensity of the K-systems light source from the control panel Integrated Electrical socket L200 IVF Op onal Features Incorpora on of a Light Source Ls14 Integrated Monitor Integrated camera Socket 1 unit. (2 units for the L226 Dual) Standard is 4 pins socket Eternal Humidifica on System Gh01 Incorporated UV Light Standard Op onal Not applicable L224 IVF L226 IVF L226 Dual L234 29

30 CONFIGURATION L100 LAF Standard Features L400 LAF Standard Features L423 L424 L426 LAF LAF LAF Ver cal Laminar Flow X X X V.O.C Pre-filter & HEPA FILTRATION X X X Two speed for the fan ( High & Low) X X X HEPA Filter Alarm indica ng HEPA filter need to be checked X X X Programming for an automac c start up of the worksta on X X X 400 LAF Op onal Features Incorporated UV Light Intergra on of addi onal Electrical sockets (Maimum 2 outlets per worksta on) L124 L125 L126 LAF LAF LAF Ver cal Laminar Flow X X X V.O.C Pre-filter & HEPA FILTRATION X X X Counter for usage hours of the fans X X X Two speed for the fan ( High & Low) X X X HEPA Filter Alarm indica ng HEPA filter need to be checked X X X Programming for an automac c start up of the worksta on X X X L100 LAF Op onal Features Incorporated UV Light Intergra on of addi onal Electrical sockets (Maimum 2 outlets per worksta on) L200 LAF Standard Features L224 L226 LAF LAF Ver cal Laminar Flow X X V.O.C Pre-filter & HEPA FILTRATION X X Counter for usage hours of the fans in the Menu X X Two speed for the fan ( High & Low) X X HEPA Filter Alarm indica ng HEPA filter need to be checked X X Programming for an automac c start up of the worksta on X X Fied Window X X L200 LAF Op onal Features Incorporated UV Light Intergra on of addi onal Electrical sockets (Maimum 2 outlets in total per worksta on) Air Speed Sensor Sliding window - placement of center opening (410 mm from side; adjustable mm from tableplate) Technical Specifica ons on G603 Overall dimensions (WDH): Tabletop (WD): Weight Ma load on overall working area: Gas and Temperature Accuracy mm mm 112 kg 10 kg Temperature Accuracy (table top) Be er than ±0.25 C of devia on Co2 gas control Be er than ±0.25% O2 gas control Be er than ±0.30% Ambient Condi ons Ma/min ambient temperature during opera on Ma/min storage temperature: Temperature Accuracy (table top) Humidity Ma humidity during opera on Ma storage humidity Filters 25/10 C 55/5 C Be er than ±0.25 C of devia on 75% r.h; non-condensending 75% r.h; non-condensending Internal Air Quality Grade A (Air is constantly circulated through HEPA, VOC filters and a UV Light): Main Filter HEPA (H14 according to DIN EN 1822) VOC Filter High-efficiency, acid-washed, granular-ac vated carbon) Gas Inline Filter Decontamina on Programme: 50mm HEPA disc filter for the protec on of internal circuit 30

31 CONFIGURATION L400 IVF Standard Features Ver cal Laminar Flow V.O.C Pre-filter & HEPA FILTRATION AluHeat technology Prepara on for a Stereomicroscope Right Side Prepara on for a Stereomicroscope Le Side Prepara on for 2 Stereomicroscopes (right & Le posi on) Hea ng surface with 3 Thermal Sensors per working area ( 6 thermal Sensors in L426 Dual) Counter for usage hours of the fans in the Menu System Two speed for the fan ( High & Low) HEPA Filter Alarm indica ng HEPA filter need to be checked Programming for an automac c start up of the worksta on Control of the Light Intensity of the K-systems light source from the control panel L400 IVF Op onal Features Eternal Humidifica on System Gh01 Etra Large Heated Area Incorporated UV Light Incorporated K-Systems Heated Glass Stage 90 mm Light source Opening Electrical socket 1 unit Incorpora on of a Light Source LS12 / LS11 Standard Op onal Not applicable L423 IVF L424 IVF L426 IVF L426 Dual Technical specifica ons G185 Standard G185 SensorTech Overall dimensions (WDH) ,5 mm ,5 mm Weight 38 kg 38 kg Temperature range in chambers Ambient to 42,9 C Ambient to 42,9 C CO 2 / O 2 range in chambers 2-10% / 2-20% 2-10% / 2-20% Connec on to 100% CO 2 and 100% N 2 Gas consump on 0,7 l/h CO 2 & 7 l/h N 2 0,7 l/h of CO 2 & 7 l/h of N2 Recovery me CO 2: < 2 min; O 2: < 4 min CO 2: < 2 min; O 2: < 4 min Datalogger system Prepared for ph monitoring Prepared for eternal CO2- und temperature measurement SMS alert func on (op onal) Power consump on (average SP: 37 C) 1,6 kwh 1,6 kwh Ambient humidity and temperature ma 75% RH & C ma 75% RH & C Hea ng plates NUNC/Falcon/Vitrolife NUNC/Falcon/Vitrolife 31

32 32 Illustration: Christina Laforce. LAFORCE ILLUSTRATION.

33 33

34 34 Notes:

35 Warranty and Liability Limited Warranty: K-Systems Kive Biotec warrants to the purchasers of all devices and products manufactured by K-Systems Kive Biotec, the product was prepared and tested in accordance with good manufacturing practices and guidelines and are in compliance to the CE norms issued by the competent authority. In the event of product failure under normal use, due to defects in material or workmanship, within a period of twenty-five months (25) months from the date of invoice of the Product and from the point of origin, the product will be repaired, or at K-Systems Kive Biotec option, replaced, at no charge. This limited warranty does not apply to products subjected to abnormal use or conditions, improper storage, damaged by accident, misuse or abuse, improper line voltage, products whose serial number has been altered, to products not shipped in accordance with the recommendations of K-Systems Kive Biotec, and/or to products altered or serviced by anyone other than K-Systems Kive Biotec authorised distributors. Distributor is responsible for the labour and travel costs during this period. This limited warranty is eclusive and in lieu of all other warranties whether written, oral, epressed or implied. In particular, K-Systems Kive Biotec does not warrant that the product is suitable for the needs of the purchaser and there are no warranties given as to merchantability or fitness for a particular purpose other than the one specified in K-Systems Kive Biotec literature that accompanies every specific product. K-Systems Kive Biotec assumes that the Purchaser is eperienced in the use of this device and is able to judge from his/her own epertise the suitability or otherwise of the product for the intended use. K-Systems Kive Biotec reserves the right to change or discontinue this product without prior notice. Liability: Because K-Systems Kive Biotec has no control or influence over the conditions under which this device is used, over its method of use or administration, or on handling of the product after it leaves its possession, K-Systems Kive Biotec takes no responsibility for the results, use and/or performance of the product. K-Systems Kive Biotec epects that use of the product will be confined to trained and epert users. In no event shall K-Systems Kive Biotec be liable for any direct or indirect damages including incidental, consequential or special damages, arising out of or in connection with the use or performance of the product. If K-Systems Kive Biotec provides you with technical documentation, this does not authorise you to perform repairs, adjustments or alterations on the device or accessories. No representative of K-Systems Kive Biotec and no vendor of the product is authorised to change any of the foregoing terms and conditions, and the purchaser accepts the product subject to all terms and conditions herein, subject always to any contrary provisions which are necessarily implied by stature or law notwithstanding the within terms and conditions. Replacement: As mentioned in the Limited Warranty, The decision whether to provide any remedy or whether to refund any portion of the purchase price shall be at the discretion of K-Systems Kive Biotec. Before returning a product for any reason, please contact your nearest K-Systems Kive Biotec distributor for assistance and instructions. Only for all customers in Denmark and Sweden, please take direct contact with our head office at: Tel: ; Fa: ; [email protected]

36 R K-SYSTEMS global network of distibutors is always close to you. The distributor for your region can be found on our website K-SYSTEMS - Kive Biotec Ltd Klintehøj Vænge 3-5 DK-3460 Birkerød, Denmark Tel.: Fa: [email protected] - Cover illustration: Christina Laforce. LAFORCE ILLUSTRATION. Catalogue-V