Risk Category. Abnormal heart rhythm. Drugs with. Thrombocythemia. Schizophrenia/ nausea. Drugs with
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1 Substantial evidence supports the conclusion that these drugs, when used as directed in labeling, can prolong the QT interval and can have a risk of Torsdes de pointes (TdP) in some patients. Generic Name Brand Names Drug Class Therapeutic Use TdP Risk Category Risk Category Route Amiodarone Cordarone, Pacerone, Nexterone Anti-aric, Anagrelide Agrylin, Xagrid Phosphodiestera se 3 inhibitor Thrombocythemia Arsenic trioxide Trisenox Anti-cancer Leukemia Azithromycin Zithromax, Zmax Antibiotic Bacterial infection, Chloroquine Aralen Anti-malarial Malaria infection Chlorpromazine Thorazine, Largactil, Megaphen Anti-psychotic / Anti-emetic Schizophrenia/ nausea,, suppository
2 Citalopram Celexa, Cipramil Anti-depressant, SSRI Depression Ciprofloxacin Cipro, Cipro- XR, Neofloxin Antibiotic Bacterial infection, Clarithromycin Biaxin, Prevpac Antibiotic Bacterial infection Cocaine Cocaine Local anesthetic Topical anesthetic topical Disopyramide Norpace Anti-aric Dofetilide Tikosyn Anti-aric Dronedarone Multaq Anti-aric Atrial Fibrillation
3 Droperidol Inapsine, Droleptan, Dridol, Xomolix Anti-psychotic / Anti-emetic Anesthesia adjunct, nausea Erythromycin E.E.S., Robimycin, EMycin, Erymax, Ery- Tab, Eryc Ranbaxy, Erypar, Eryped, Erythrocin Stearate Filmtab, Erythrocot, E-Base, Erythroped, Ilosone, MY- E, Pediamycin, Zineryt, Abboticin, Abboticin-ES, Erycin, PCE Dispertab, Stiemycine, Acnasol, Tiloryth Antibiotic Bacterial infection; increase GI motility,
4 Escitalopram Cipralex, Lexapro, Nexito, Anxiset-E (India), Exodus (Brazil), Esto (Israel), Seroplex, Elicea, Lexamil, Lexam, Entact (Greece), Losita (Bangladesh), Reposil (Chile), Animaxen (Colombia), Esitalo (Australia), Lexamil (South Africa) Anti-depressant, SSRI Major depression/ Anxiety disorders Flecainide Tambocor, Almarytm, Apocard, Ecrinal, Flécaine Anti-aric
5 Halofantrine Halfan Anti-malarial Malaria infection Haloperidol Haldol (US & UK), Aloperidin, Bioperidolo, Brotopon, Dozic, Duraperidol (Germany), Einalon S, Eukystol, Halosten, Keselan, Linton, Peluces, Serenace, Serenase, Sigaperidol Anti-psychotic Schizophrenia, agitation, Ibutilide Corvert Anti-aric Levofloxacin Levaquin, Tavanic Antibiotic Bacterial infection,
6 Methadone Dolophine, Symoron, Amidone, Methadose, Physeptone, Heptadon Opiate Pain control, narcotic dependence, Moxifloxacin Avelox, Avalox, Avelon Antibiotic Bacterial infection, Ondansetron Zofran, Anset, Ondemet, Zuplenz, Emetron, Ondavell, Emeset, Ondisolv, Setronax Anti-emetic Nausea, vomiting, Pentamidine NebuPent, Pentam Antibiotic Pneumocystis pneumonia, inhaled Pimozide Orap Anti-psychotic Tourette's tics
7 Procainamide (Oral off US mkt) Pronestyl, Procan Anti-aric Quinidine Quinaglute, Duraquin, Quinact, Quinidex, Cin-Quin, Quinora Anti-aric, Sevoflurane Ulane, Sojourn Anesthetic, general Anesthesia inhaled Sotalol Betapace, Sotalex, Sotacor Anti-aric Thioridazine Mellaril, Novoridazine, Thioril Anti-psychotic Schizophrenia Vandetanib Caprelsa Anti-cancer Thyroid cancer
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