CURRICULUM VITAE. I. General Biographical Information: A. Personal: Sergio Gugisch Moreira, Jr., M.D. Married to Samantha J.C.

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1 I. General Biographical Information: A. Personal: CURRICULUM VITAE Name: Status: Sergio Gugisch Moreira, Jr., M.D. Married to Samantha J.C. Moreira B. Citizenship: U.S. Citizen C. Professional Information: Current: East Texas UroCenter 1320 N. University Dr, Suite A Nacogdoches, TX Phone: (936) Fax: (936) Previous: Tampa Bay Urology 2282 W Virginia Ave, Tampa, FL Phone:(813) D. Licensure: Texas Medical Board License M8194 Valid until 11/30/2014 Florida Department of Health License: ME89888 Valid until 01/31/2014 DEA# BM ECFMG Certificate No Valid indefinitely Parana, Brazil, CRM 14864

2 Page 2 E. Board Certification: Diplomate of the American Board of Urology, March 2007 Brazilian Medical Association and Brazilian Urologic Society (Board of Urology) 10/98 Certified Urologist (#28365). Ranked in the top 4%. F. Awards/Scholarships: 1. Honorary Member of Panamanian Urological Society, April Society of Laparoendoscopic Surgeons (SLS): 2004 SLS Outstanding Laparoendoscopic Resident Surgeon. April SSRM (Society for the Study of Male Reproduction) Traveling Fellowship Award. US$1000,00. March Milton Coplan Pyelogram Hour Second place US$300,00. Florida Urological Association, Orlando, Florida, August International Scholar Grant awarded by Confederacion Americana de Urologia (CAU) US$10,

3 Page 3 G. Education: Postgraduate Training: Chief Resident in Urology 01/05 07/05 University of South Florida College of Medicine and Affiliated Hospitals Tampa, Florida USA Residency in Urology 07/01 07/05 University of South Florida College of Medicine and Affiliated Hospitals Tampa, Florida USA Internship, General Surgery 07/00 07/01 University of South Florida College of Medicine and Affiliated Hospitals Tampa, Florida USA Fellow in Male Reproductive Medicine and Surgery, 07/99-06/00 Scott Department of Urology, Baylor College of Medicine, Houston, Texas USA Postdoctoral Research Fellow 02/99-06/99 in Male Reproductive Medicine and Surgery, Scott Department of Urology, Baylor College of Medicine, Houston, Texas, USA Residency, Urology, Hospital Nossa Senhora das Graças, Curitiba, Brazil Residency, General Surgery, Hospital Nossa Senhora das Graças, 1996 Curitiba, Brazil Graduate: Pontificia Universidade Catolica do Parana, Curitiba, Brazil 1994 Degree: M.D. Undergraduate: Colegio Dom Bosco, Curitiba, Brazil 1988

4 Page 4 H. Appointments: National Proctor for Intuitive Surgical DaVinci Surgical Procedures National and International Proctor for Boston Scientific and Lumenis Holmium Laser Surgical Procedures 2007-Current 2005 Current Teaching Assistant - Department of Surgical Techniques, 1992 Pontificia Universidade Catolica do Parana, Curitiba, Brazil II. Research Information: A. Research Experience Testicular stem-cell transplantation in mice after radiation therapy 1999 Preceptor: Dolores J. Lamb, Ph.D. B. Professional Societies: American Urological Association Texas Medical Association American Society for Reproductive Medicine American Society of Andrology Society for the Study of Male Reproduction The Society of Laparoendoscopic Surgeons Florida Urological Association Brazilian Urologic Society Panamanian Urological Society

5 Page 5 C. Clinical Research: 1. A Randomized, Double-Blind, Placebo Controlled, Parallel Group, Multi-Center Study Investigating the Efficacy and Safety of a Fast-Dissolving ( Melt ) Formulation of Desmopressin for the Treatment of Nocturia in Adults. May 2007 to August A Multicenter, Randomized, Parallel Group, Double-Blind, Placebo Controlled Flexible Dose Study to Assess the Efficacy and Safety of Viagra (Sildenafil Citrate) in Men with Erectile Dysfunction (ED) who do not Self Identify. April 2007 to July A Multicenter, Randomized, Placebo-Controlled, Double-Blind Phase 3 Trial of Single-Dose Intravesical EOquin as a Surgical Adjuvant Instilled in the Early Postoperative Period in Patients Undergoing Transurethral Resection for Noninvasive Bladder Cancer. April 2007 to February A Multi-Center, Randomized, Double-Blind, Placebo-Controlled Efficacy and Safety Study of Testosterone Gel 1.62% for the Treatment of Hypogonadal Men. February 2007 to July A Multi-Center, Double-Blind, Placebo-Controlled Study of the Efficacy and Safety of Daily Dosing with Oxybutynin Topical Gel to Treat the Symptoms of Overactive Bladder. December 2006 to May A multicenter, double-blind phase 3B study to compare the safety and clinical efficacy of levofloxacin 750 MG for 2 weeks and Levofloxacin 750 MG for 3 weeks to that of Levofloxacin 500 MG for 4 weeks in the treatment of chronic prostatitis. December 2006 to February Tadalafil 5 mg Once a Day Compared to Placebo in Improving Sexual Quality of Life. November 2006 to October A 12-week, open-label, non-randomized, multicenter study to evaluate the patient's perception of outcome after treatment with darifenacin in overactive bladder patients dissatisfied with previous anticholingeric therapy. July 2006 to October A Two-Arm, Open-Label, Randomized, Multi-Center Pharmacokinetic and Long-term Safety Study of Intramuscular Injections of 750 mg and 1000 mg Testosterone Undecanoate In Hypogonadal Men. April 2006 to August A Multicenter, Randomized, Double-Blind, Study To Evaluate The Safety And Efficacy Of Oxybutynin Vaginal Ring Releasing 4 mg/day Versus 6 mg/day Versus Placebo In Women Diagnosed With Overactive Bladder Who Have Symptoms Of Predominant Or Pure Urge Incontinence, Urgency, And Frequency. March 2006 to November 2006.

6 Page A Multi-Center Open-Label Evaluation of the Safety of Silodosin in the Treatment of Signs and Symptoms of Benign Prostatic Hyperplasia. October 2005 to November Multicenter, Randomized, Double-Blind Placebo-Controlled Parallel Study of Men With Mild to Moderate Erectile Dysfunction to Evaluate the Efficacy of Viagra 8 Hours Post-Dose (1240). October 2005 to June A Double-Blind, Multicenter International (US and Europe) Randomized Placebo-Controlled Study of Safety and Efficacy of Trospium Chloride 60 mg Modified Release Capsules Versus Placebo, Once Daily, for 12 weeks Followed by a 9-Month Open Label Treatment Phase in Patients With Overactive Bladder. August 2005 to November C. Publications - Published in Peer-Reviewed Journals: 1. Alejandro Miranda-Sousa, Michael Keating, Sergio Moreira, Mark Baker, Rafael Carrion. ConcomitantVentral Phalloplasty During Penile Implant Surgery: A Novel Procedure That Optimizes Patient Satisfaction and Their Perception of Phallic Length After Penile Implant Surgery. Journal of Sexual Medicine issue 4:5 article 551, Sergio G. Moreira, Jr., John D. Seigne, Raul C. Ordorica, Jorge L. Lockhart. Cutaneous Ureterostomies: Should the Issue be Revisited? Surgeon s Corner-Contemporary Urology July, Sergio G. Moreira, Jr., John D. Seigne, Raul C. Ordorica, Julio M. Pow-Sang, Jorge L. Lockhart. Devastating complications following brachytherapy in the treatment of prostate adenocarcinoma. Abstract 3854, 2004 AUA Annual Meeting, San Francisco, California, May Sergio G. Moreira, Rafael E. Carrion, John D. Seigne, Raul C. Ordorica, Jorge Lockhart. Nonconventional alternatives for ureteral replacement. Abstract 3887, 2004 AUA Annual Meeting, San Francisco, California, May Sergio G. Moreira, Jr., John D. Seigne, Jorge L. Lockhart. Alternatives for ureteral replacement. Contemporary Urology, 2004 Mar;16(3): Sergio G. Moreira, Jr., John D. Seigne, Raul C. Ordorica, Julio M. Pow-Sang, Jorge L. Lockhart. Devastating complications following brachytherapy in the treatment of prostate adenocarcinoma. BJU Int Jan;93(1):31-5..

7 Page 7 7. Rafael E. Carrion, Raul Ordorica, Sergio G. Moreira, Jorge Lockhart. Conventional and nonconventional alternatives for ureteral replacement. Paper 401, 2003 AUA Annual Meeting, Chicago, Illinois, April J Christopher Webster, Sergio G. Moreira, Alan B. Cantor, John D. Seigne, Julio M. Pow- Sang. A prospective, randomized trial to standardize the location and time of local anesthesia administration in transrectal ultrasound-guided biopsies of the prostate. Paper 1605, 2003 AUA Annual Meeting, Chicago, Illinois, April Moreira SG Jr, Pow-Sang JM Evaluation and management of adrenal masses. Cancer Control Jul-Aug;9(4): Review. 10. Moreira Jr SG, Lamb D: Advances in Andrology Using Animal Models. Contemporary Urology 79-84, Aug, Mifsud A, Sim CK, Boettger-Tong H, Moreira S, Lamb DJ, Lipshultz LI, Yong EL. Trinucleotide (CAG) repeat polymorphisms in the androgen receptor gene: molecular markers of risk for male infertility. Fertil Steril Feb;75(2): Moreira SG Jr, Brannigan RE, Spitz A, Orejuela FJ, Lipshultz LI, Kim ED. Side-effect profile of sildenafil citrate (Viagra) in clinical practice. Urology Sep 1;56(3): David J. Cozzolino, Sergio G. Moreira, Jr., Margaret A. Goodell, Larry I. Lipshultz, Dolores J. Lamb. Identification and isolation of spermatogonial stem cells. Paper 1142, Podium 22, 2000 AUA 95 th Annual Meeting, Atlanta, Georgia, April/May David J. Cozzolino, Sergio G. Moreira, Jr, Gene Wilson, Marvin L. Meistrich, Larry I. Lipshultz, Dolores Lamb. Recovery of spermatogenesis after radiation and chemotherapy by spermatogonial cell transplantation and Gonadotropin-releasing hormone (GnRH) agonist treatment in a mause model. Poster 1308, 2000 AUA 95 th Annual Meeting, Atlanta, Georgia, April/May Benjamin N. Hendin, Aleksey Domozhirov, William W. Lin, Sergio Moreira, Francisco J. Orejuela, Sandra Carson, Pauline Cisneros, Larry I. Lipshultz, Dolores J. Lamb Incubation of testicular sperm enhances oocyte fertilization with ICSI procedures. Poster 1527, 2000 AUA 95 th Annual Meeting, Atlanta, Georgia, April/May Moreira Jr SG, Lipshultz LI. Management of male infertility. For publication in the Digital Journal of Urology (www.dju.com), Coelho JCU, Vianna RMM, Moreira SG Jr, Campos ACL, Torres LFB, Pisani JC: Giant adenoma of Brunner s glands. GED, vol. 15, no. 6, pp , Nov/Dec 1996.

8 Page 8 D. Abstracts: 1. Rodriguez A, Burday D, Moreira S, Pow-Sang JM: Management of Major Complications Following Extraperitoneal Laparoscopic Radical Prostatectomy. Southeastern Section, AUA, Scientific Program, 69 th Annual Meeting, March Rodriguez A, Burday D, Moreira S, Pow-Sang JM: Clinical Characteristics of Penile Carcinoma and Complications Related to Inguinal Lymph Node Dissection. Southeastern Section, AUA, Scientific Program, 69 th Annual Meeting, March Sergio Moreira, Jorge Caso, Jorge L. Lockhart, John D. Seigne: Cutaneous Ureterostomy: A place for everything and everything in its place. New England Section AUA, Scientific Program, August Sergio G. Moreira, Jr., John D. Seigne, Raul C. Ordorica, Julio M. Pow-Sang, Jorge L. Lockhart. Devastating complications following brachytherapy in the treatment of prostate adenocarcinoma. Abstract 3854, 2004 AUA Annual Meeting, San Francisco, California, May Sergio G. Moreira, Rafael E. Carrion, John D. Seigne, Raul C. Ordorica, Jorge Lockhart. Non-conventional alternatives for ureteral replacement. Abstract 3887, 2004 AUA Annual Meeting, San Francisco, California, May Sergio G. Moreira, Jr., Raviender Bukkapatnam, Osvaldo F. Padron. Correlation Between Inhibin B Levels and Sperm Retrieval in Men With non-obstructive Azoospermia. Southeastern Section, AUA, Scientific Program, 68 th Annual Meeting, March Raul Ordorica, Alejandro J. Miranda-Sousa, Sergio Moreira. The Z Anastomosis Repair of Proximal Urethral Strictures. Southeastern Section, AUA, Scientific Program, 68 th Annual Meeting, March Miranda-Sousa AJ, Bukkapatnam R, Moreira SG, Hoffman M, Ordorica RC, Lockhart JL. Polypropylene Sling For Females With Stress Urinary Incontinence (SUI). Southeastern Section, AUA, Scientific Program, 68 th Annual Meeting, March Rafael E. Carrion, Raul Ordorica, Sergio G. Moreira, Jorge Lockhart. Conventional and nonconventional alternatives for ureteral replacement. Abstract , 2003 AUA Annual Meeting, Chicago, Illinois, April 2003.

9 Page Sergio G. Moreira, Jr, Raul Ordorica, John D. Seigne, Julio M. Pow-Sang, Jorge Lockhart: Devastating Complications Following Brachytherapy in the Treatment of Prostate Adenocarcinoma. Southeastern Section, AUA, Scientific Program, 67 th Annual Meeting, March Christopher Webster, Sergio G. Moreira, Alan B. Cantor, John D. Seigne, Julio M. Pow- Sang. A prospective, randomized trial to standardize the location and time of local anesthesia administration in transrectal ultrasound-guided biopsies of the prostate. Abstract , 2003 AUA Annual Meeting, Chicago, Illinois, April Rafael Carrion, John Seigne, Sergio Moreira, Raul Ordorica, Jorge Lockhart: Conventional and non-conventional alternatives for ureteral replacement. Southeastern Section, AUA, Scientific Program, 67 th Annual Meeting, March Bukkapatnam R, Moreira SG*, Ordorica R, Seigne JD, Baker M, and Lockhart JL: Cutaneous Ureterostomy in Adults: An Improved Technique and Comparison with Ileal Conduits. Southeastern Section, AUA, Scientific Program, 67 th Annual Meeting, March Rodriguez F, Mora L, Moreira S, Benson K, Ahmad N, Cantor A, Pow-Sang J: Poor Performance of Urinary Nuclear Matrix Protein 22 (NMP 22) for Detection of Recurrence of Transitional Cell Carcinoma (TCC) of the Bladder. Southeastern Section, AUA, Scientific Program, 66 th Annual Meeting, March David J. Cozzolino, Sergio G. Moreira, Jr., Margaret A. Goodell, Larry I. Lipshultz, Dolores J. Lamb. Identification and isolation of spermatogonial stem cells. Paper 1142, Podium 22, 2000 AUA 95 th Annual Meeting, Atlanta, Georgia, April/May David J. Cozzolino, Sergio G. Moreira, Jr, Gene Wilson, Marvin L. Meistrich, Larry I. Lipshultz, Dolores Lamb. Recovery of spermatogenesis after radiation and chemotherapy by spermatogonial cell transplantation and Gonadotropin-releasing hormone (GnRH) agonist treatment in a mause model. Poster 1308, 2000 AUA 95 th Annual Meeting, Atlanta, Georgia, April/May Benjamin N. Hendin, Aleksey Domozhirov, William W. Lin, Sergio Moreira, Francisco J. Orejuela, Sandra Carson, Pauline Cisneros, Larry I. Lipshultz, Dolores J. Lamb Incubation of testicular sperm enhances oocyte fertilization with ICSI procedures. Poster 1527, 2000 AUA 95 th Annual Meeting, Atlanta, Georgia, April/May Orejuela FJ, Spitz A, Brannigan RE, Moreira Jr SG, Kim ED, Lamb DJ, Lipshultz LI. Relationship between pellet sperm analysis (virtual azoospermia) and serum Folicule Stimulating Hormone (FSH) levels in patients with Non-Obstructive azoospermia (NOA). Poster 394, 1999 ASRM 55 th Annual Meeting, Toronto, Canada, Sep Spitz A, Kim ED, Witte MN, Brannigan RE, Orejuela FJ, Moreira Jr SG, Lipshultz LI. Impact of testosterone levels on erectile response to trimix intracavernosal injections. Poster 269, 1999 ASRM 55 th Annual Meeting, Toronto, Canada, Sep 1999.

10 Page Moreira Jr SG, Brannigan Re, Spitz A, Orejuela FJ, Lipshultz LI, Kim ED. Side effect profile of Sildenafil citrate (Viagra ) in clinical practice. Poster 393, 1999 ASRM 55 th Annual Meeting, Toronto, Canada, Sep Moreira SG Jr, Kato M, Oliveira B, Hatschbach SB, Montenegro MF: Primary gastric lymphomas. Anais XIII Congresso Brasileiro de Cancerologia, Porto Alegre, RS, Brazil, p 28, Moreira SG Jr, Kato M, Oliveira B, Hatschbach SB, Montenegro MF: Carcinoid tumors of the appendix. Anais XIII Congresso Brasileiro de Cancerologia, Porto Alegre, RS, Brazil, p 42, Moreira SG Jr, Pinto AP, Sampaio LA, Hatschbach SB, Callaço LM: Fine needle aspiration in the diagnosis of breast lesions. Anais XIII Congresso Brasileiro de Cancerologia, Porto Alegre, RS, Brazil, p 42, Moreira EL, Slongo LE, Frehse JM, Bendhack LA, Neto NF, Sobreiro BP, Bendhack ML, Moreira Jr SG, Brasil J, Bendhack DA: Endoscopic treatment of the lower ureteral stones. Anais I ENCAM, p.39, Brazil, Moreira EL, Bendhack ML, Sobreiro BP, Moreira Jr SG, Brasil J, Bendhack DA: Treatment of a calcified ureteral stent-case report. Anais I ENCAM p.38, Brazil, Neto NF, Sobreiro BP, Moreira Jr SG, Bendhack ML, Brasil J, Bendhack DA: Retrocaval ureter associated with staghorn calculi-case report. Anais I ENCAM p.40, Brazil, Bendhack ML, Sobreiro BP, Moreira Jr SG, Miasaki FY, Borges AM: Frequency and localization of positive surgical margins in radical prostatectomies. Anais I ENCAM p.41, Brazil, Moreira EL, Sobreiro BP, Moreira Jr SG, Beira S, Timi JR, Raskin S, Brasil J, Bendhack DA: Radical surgery in the treatment of scrotal and penile verrucous lymphedema. Anais I ENCAM p.42, Brazil, Bendhack LA, Slongo LE, Frehse JM, Moreira EL, Neto NF, Sobreiro BP, Bendhack ML, Moreira Jr SG, Brasil J, Bendhack DA: Treatment of staghorn renal calculi through percutaneous access and utilizing ultrasonic lithotridor. Anais I ENCAM p.42, Brazil, Moreira EL, Sobreiro BP, Moreira Jr SG, Brasil J, Bendhack DA: Treatment of male urethral diverticula-case report. Anais I ENCAM p.44, Brazil, Moreira EL, Sobreiro BP, Moreira Jr SG, Beira S, Timi JR, Raskin S, Brasil J, Bendhack DA: Scrotal verrucous lymphedema in a patient with Noonan s syndrome. Anais XXII

11 Page 11 Congresso dos residentes e academicos - Hospital Nossa Senhora das Graças, Curitiba, Brazil, Bendhack ML, Sobreiro BP, Moreira Jr SG, Miasaki FY, Borges AM: Positive surgical margins in radical prostatectomies. Anais XXII Congresso dos residentes e academicos - Hospital Nossa Senhora das Graças, Curitiba, Brazil, Moreira EL, Bendhack ML, Sobreiro BP, Moreira Jr SG, Brasil J, Bendhack DA: Calcified ureteral stent removal-case report. Anais XXII Congresso dos residentes e academicos - Hospital Nossa Senhora das Graças, Curitiba, Brazil, Moreira EL, Sobreiro BP, Moreira Jr SG, Brasil J, Bendhack DA: Treatment of male urethral diverticula. Anais XXII Congresso dos residentes e academicos Hospital Nossa Senhora das Graças, Curitiba, Brazil, Bendhack LA, Slongo LE, Frehse JM, Moreira EL, Neto NF, Sobreiro BP, Bendhack ML, Moreira Jr SG, Brasil J, Bendhack DA: Role of percutaneous ultrasonic nephrolithotripsy in the treatment of staghorn renal calculi-49 cases. Anais XXII Congresso dos residentes e academicos - Hospital Nossa Senhora das Graças, Curitiba, Brazil, Moreira EL, Slongo LE, Frehse JM, Bendhack LA, Neto NF, Sobreiro BP, Bendhack ML, Moreira Jr SG, Bendhack DA: Transureteroscopic ureterolithotripsy-eficiency and complications in 102 procedures. Anais XXII Congresso dos residentes e academicos - Hospital Nossa Senhora das Graças, Curitiba, Brazil, E. Book Chapters: 1. Sergio G. Moreira, Jr.: Male Infertility. Manual of Surgical Clinics: General Surgery and Specialties. Atheneu Publications. In Press, Sergio G. Moreira, Jr.: Benign Prostatic Hyperplasia. Manual of Surgical Clinics: General Surgery and Specialties. Atheneu Publications. In Press, Sergio G. Moreira, Jr.: Bladder: Function and Dysfunction. Manual of Surgical Clinics: General Surgery and Specialties. Atheneu Publications. In Press, Sergio G. Moreira, Jr.; Michael Keating:. Diagnostic Studies and Techniques in the Urinary Tract. Manual of Surgical Clinics: General Surgery and Specialties. Atheneu Publications. In Press, John C. Webster; Sergio G. Moreira, Jr.:: Urologic Trauma. Manual of Surgical Clinics: General Surgery and Specialties. Atheneu Publications. In Press, 2007.

12 Page 12 6 Moreira Jr SG, Ordorica RC, Das S. History of Laparoscopy. Textbook of Laparoscopic Urology. Informa Healthcare USA Moreira Jr SG, Seigne JD. Urological Tumors In Pocket Surgical Oncology, Orejuela FJ, Moreira Jr SG, Lipshultz LI. Varicocele. In Male Infertility, Paulo Augusto Neves and Nelson Rodrigues Netto Jr, Atheneu Editorial, Brazil, F. Lectures: 1. Speaker at the Nacogdoches Chamber of Commerce Leadership Class of Medical Luncheon: Robotic-Assisted Surgery, December, Speaker at the Know Your Status Luncheon at Nacogdoches Memorial Hospital with The National Football League and Intuitive Surgical Systems, October, Speaker at the Nacogdoches Chamber of Commerce Fourth Friday Luncheon: Advances in Robotic Surgery, August, Speaker at the X South Brazilian Urology Congress 2010 Severe Peyronie s Disease, Curitiba, Parana, Brazil, July Speaker at the X South Brazilian Urology Congress 2010 Penile Implant in severe penile deformities and acute ischemic priapism, Curitiba, Parana, Brazil, July Speaker at the X South Brazilian Urology Congress 2010 Penile Implants, Curitiba, Parana, Brazil, July Speaker at the X South Brazilian Urology Congress 2010 Neuromodulation, Curitiba, Parana, Brazil, July Speaker at the X South Brazilian Urology Congress 2010 BPH: HoLAP and HoLEP, Curitiba, Parana, Brazil, July Invited Professor Holmium Laser Techniques in Urology: Lecture and Live Surgeries. Hospital Nossa Senhora das Gracas, Curitiba, Parana, Brazil. September, Guest Speaker at Grand Rounds, Department of Urology, University of Texas at Houston Holmium Laser: Uses in Urology, April 17, 2009.

13 Page Official Instructor in Holmium Laser Techniques, Panamanian Urological Society (CUSA) Panama City, Panama, April Guest Speaker at Grand Rounds, Department of Gynecology and Obstetrics, University of South Florida Evaluation and Management of Male Infertility, March 21, Speaker: Pearls In Laparoscopic Prostatectomy at the Fifteenth Annual Advances in Urology, Key West, FL, March/April Speaker: Cutaneous Ureterostomies: From Stricture to Diversion at the Fifteenth Annual Advances in Urology, Key West, FL, March/April Basic Lecture in Prostate Cancer; 2 nd year year medical students at the University of South Florida, February 12, General Aspects in Urology; 3 rd year medical students at the University of South Florida, December 6, 2001.

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