Master of Science Program in Medical Sciences (Revised Curriculum 2007)

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1 Master of Science Program in Medical Sciences (Revised Curriculum 2007) 1. Name of curriculum Master of Science Program in Medical Sciences 2. Degree offered Master of Science (Medical Sciences) M.Sc. (Medical Sciences) 3. Responsible office Office of Graduate Studies, Faculty of Medicine, Thammasat University 4. Philosophy and objectives of the curriculum 4.1 Philosophy Faculty of Medicine,Thammasat University has a firm intention in extending medical studies and medical science researchs. Therefore, the production of high level medical science personnels with competency and skills in doing research works by his own and with others is emphasized. We expect that the graduates are able to gain new knowledges that usefully applied in everyday life and can select proper technologies in doing so. Also, the graduates could build up their ability in becoming a world leader scientist. The Faculty has the policy in encouraging and supporting the personnels to increase their capability in doing research work in parallel with teaching both the graduates and undergraduates. The collaboration with the scientific faculties of either Thammasat University or other universities and institutes at both national and international levels will be urged to develop. 4.2 Objectives To provide master s degree graduates specialized and fully proficient in integrated medical sciences both in pre-clinical and clinical aspects and in searching for new knowledges that can be usefully applied, in order to meet the national manpower need in this field To encourage our faculty staffs to acquire potential and motivation for selfdevelopment in research and graduate training, as well as to establish collaborations in medical sciences with other faculties of thammasat university and of other universities or institutes. 5. Teaching schedule. Academic year 2007 onwards. 6. Student s qualifications. Student qualifications are according to the regulation of Thammasat University for Graduate Studies 1998, item 8, as follows: 6.1 Graduates with a bachelor s degree Holding a bachelor s degree in Health Sciences, Biological Sciences or other related sciences from the recognized universities or institutes within or outside the country Holding a minimum cumulative GPA of 2.50 or with a consent of the graduate studies committee of the Faculty of Medicine, Thammasat University. 6.2 Student who has enrolled in our doctoral program and failed to pass the second qualifying examination, he/she is eligible for transferring to the master s level and has to meet the specific requirements for the master s degree level.

2 6.3 The applicants must not have serious contageous diseases which may interfere with their studies. 6.4 The applicants must be flawless of conducts and behaviors. 6.5 The applicants must not have been registered in other faculties of Thammasat University or in other University / Institutes unless otherwise specially granted by the Thammasat University Council. 7. Admission of Applicants 7.1 Admission of applicants will be organized by the graduate studies committee, Thammasat University. It consists of written and oral examinations. 7.2 Applicants must have successfully passed an English proficiency test (within the period of 2 years) according to the standard specified by Thammasat University (TU-GET, TOEFL or IELTS). Applicants who do not meet the requirement may be admitted to the program on probation and must have successfully passed the test at P level before applying for thesis examination. 7.3 Other qualifications are required according to the regulation concerning Bachelor Degree Education of Faculty of Medicine, or of Thammasat University. 8. Academic System 8.1 The study program is a regular bi-semester day program and is taught in Thai. 8.2 The course is opened only for education plan A (2), requiring both attendance of study courses and preparation of a thesis. 8.3 The curriculum consists of not less than 39 credits, with 17 credits of prescribed subjects, and 22 credits of thesis. 8.4 Curriculum reguirements Thesis To be able to register for thesis, the students must have registered for at least 12 credits with a cumulative GPA of at least Thesis may be written in English or thai The Faculty will appoint the thesis advisors who will give advices in thesis preparation and writing. The advisors are composed of major and co-advisors (if any) with the following qualifications: a Ph.D. or comparable or Associate Professor in the specialized subjects studied with adequate experiences in research works (their thesis research work excluded) The students have to prepare thesis proposal for thesis proposal examination under the supervision of advisors. The Faculty will appoint at least 3 examination committees composed of one of advisors, one of faculty s teachers and another one external examiner with the same qualifications in item Thesis Examination The thesis examination is under the regulation of Thammasat University. The examination committee must not be either the advisor or co-advisor. The result of examimation at S level must be a concensus of the whole committee Test of Foreign Language The students must pass the foreign language requirement prior to defense of their thesis Outstanding student who has earned a minimum of 12 credits with a cumulative GPA of 3.50, he/she is eligible for transferring to the doctoral level with an agreement of his/her advisors and in consultation with the graduate studies

3 committee. Also, he/she has to meet the specific requirements (qualifying examination, dissertation credits, study time) for the doctoral level (item 9.3) Once the students have transfered to the doctoral level, they cannot transfer back to the master s level Students enrolling with unsatisfied condition may be assigned to take some supplementary courses as audit courses, or gain level P (credits not counted). 9. Study Time 9.1 The bachelor degree students have study time of at least 4 semesters (2 academic years) and not more than 8 semesters (4 academic years) counted from the day of registration. 9.2 The master degree students transfered from doctoral level have study time of at least 4 semesters (2 academic years) and not more than 8 semesters (4 academic years) counted form the day of registration. 9.3 The master degree student transfered to doctoral level according to No can have study time not more than 16 semesters (8 academic years) counted from the day of registration. 10. Registration The students have to register at least 6 credits and not more than 12 credits in each semester. Registration of other courses must follow the regulation of Thammasat University for Graduate Studies 1998 and the second revised issue Evaluation and Graduation 11.1 Evaluation Evaluation is devided into 9 levels as follows : Levels A A- B+ B B- C+ C D F Grades Evaluation for audit courses is devided into two levels; P for passed and N for not passed. In case, the student has to attend the basic science courses, the score C is regarded as P and the score under C is regarded as N Only the credits of the courses the student gain S or not under C levels will be counted To pass the examination, the student has to gain S or not under C scores. In case she/ he fails in any of the courses required they must register to repeat the course according to the regulation of Thammasat University for Graduate Studies 1998 and the second revised issue The student who gains either U or D or F level in any required course can register to repeat the course only one time and she/he must gain S or not under C level, otherwise her or his name will be withdrawn from student status. In case of prescribed elective course, they can either register to repeat that course or register for other course instead and once they have passed not under C level in any course they can not register to repeat their study in that course again Thesis evaluation is devided into 2 levels, S for passed and N for not passed. The credit gained will not be counted in the average.

4 Tests of foreign language is also classified at 2 levels, P (passed) and N (not passed) and the credits gain will not be counted. The students must pass P level prior to their thesis examination. This process is under the regulation of Thammasat University for graduate Studies 1998 and the second revised issue 2002 and the regulation for tests of oreign languages Degree Requirements : The students must have completed all subjects examination according to the course program and implementing terms and fulfilled all conditions specified by the Faculty obtained a cumulative GPA of at least passed the foreign language examination with P level passed the thesis oral examination with S level and submitted the thesis prepared according to the format of the Thammasat University their thesis research work published or admitted for publication in the academic journals or presented in the academic meetings or conferences with proceedings fulfilled all the conditions reguired by Thammasat University and the Faculty of Medicine and also have paid all the debits she / he owed to the university or Faculty of Medicine, Thammasat University Teaching Staffs Name and qualifications of permament staffs and staffs who are responsible for the curriculum. Orde r Name of teachers Degree 1 Assoc.Prof. Paskorn Sritipsukho Thai Board of Family Medicine, Thai General Medical Council, Thai Board of Pediatrics, Prince of Songkla University, MD. Faculty of Medicine Chulalongkorn University. 2 Asst.Prof.Dr. Junya Sc.D. (Biostatistics),Tulane University, U.S.A Pattaraarchachai 3 Dr. Sirikul Manochantr Ph.D. (Anatomy), Mahidol University 4 Dr. Borisut Sanmano, Ph.D. (Medical Sciences), Juntendo University, Tokyo. HANPANICH 5 Dr. Nongluk Sriwilaijaroen Ph.D. (Biochemistry), Mahidol University. * No 1-3 are responsible for the curriculum management 13. Number of students required Academic year Number required for M.Sc. M.Sc. M.Sc. M.Sc. M.Sc. New students Old students Total Graduation Places and equipments Places including equipments of Faculty of Medicine, of other Faculties of Health Science Center and of Thammasat University Hospital will be of use for the graduate studies.

5 15. Libraries and IT The students can use the services of Thammasat University library, the Medicine Science library and of other university libraries Books and journals (upto September 2006) Thammasat University library Books 1,111,169 items. Thai 757,158 items. English 354,011 items. Journals 1,140 items. Thai 534 items. English 906 items. Medicine Science library Books 38,105 items. Thai 17,963 items. English 20,142 items. Journals 350 items. Thai 100 items. English 250 items IT and multimedia The students can search the informations required from the database by microcomputer which can give the following services : Database ipac 17 sets Computer Aided Instruction (CAI) 5 sets Ready-made Database (CD-ROM) 28 sets The students can search informations by themselves using the following databases - Database (CD-ROM) - References of MEDLINE and CNAHL - CAI and Electronic books 30 items. - Video tapes 300 items. - Slides 25 items Electronic journals 20,000 items. 16. Budget The budget estimated for one M.Sc. graduate is 90, Bahts (the expenses for research works not included). 17. The curriculum The students must complete all the courses required and have gained the credits as required by the curiculum Number of credits required. - Not less than 39 credits for the bachelor degree. - Not less then 39 credits for the one who transfers from the Ph.D. level (item 6.2) 17.2 The curriculum structure Total requirement of the whole course 39 credits - Prescribed required subjects 17 credits Required subjects (compulsory) 4 credits Prescribed elective subjects* 10 credits - Related topics 4 credits

6 - Related subjects 6 credits - Elective Subjects (general) 3 credits - Thesis 22 credits * The elective subjects are selected under the supervison of advisor or of graduate studies committee of the Faculty of Medicine, Thammasat University Code of Subjects The code of subjects in the course is composed of two letters and three digits as follows : The letters preceeding the digits i.e. MS means the course provided by the Faculty of Medicine, Thammasat University The 3 digits means the followings : (1) The single digit 0 means required subjects 1-6 means prescribed elective subjects 7-9 means elective subjects (general) (2) The tenth digit 0 means general subjects 1 means Cellular and Molecular Biology 2 means Nutraceutical 3 means Pharmacology 4 means Reproductive Medical Sciences 5 means Molecular Physiology and Biophysics 6 means Biochemistry and Molecular Biology 7 means Epidemiology and Health Research 8 means Psychological Health and Behavioral Sciences 9 means Medical Informatics (3) The hundred digits 6-7 means graduate courses 8 means M.Sc. thesis 17.4 List of subjects Required subjects (4 credits) (Lecture-Lab-SDL) MS 600 Research Methodology and Ethics 2 (2-0-6) MS 700 Applied Statistics 2 (2-0-6) Prescribed elective subjects (10 credits). The students must register for a minimum of 10 credits of their specialized area of study with consultation to their mentor, the students may have to take the related subjects or topics from relevant major areas to fulfill their requirements For the prescribed related elective topics, the students have to register for a minimum of 4 credits of either the Basic Medical Sciences or Applied Medical Sciences. Basic Medical Sciences (Lecture-Lab-SDL) MS 701 Cellular and Molecular Biology 3 (3-0-9) MS 702 Seminar in Medical Sciences 1 (1-0-3)

7 Applied Medical Sciences MS 703 Epidemiology 3 (3-0-9) MS 704 Seminar in Epidemiological and Health Research 1 (1-0-3) For the prescribed related elective subjects the students have to select to register these subjects under supervision of advisor for at least 6 credits. Basic Medical Sciences (Lecture-Lab-SDL) Cellular and Molecular Biology MS 613 Advanced Cellular Biology 3 (3-0-9) MS 614 Advanced Molecular Biology 3 (3-0-9) MS 615 Basic Techniques in Cellular and Molecular Biology 2 (1-2-5) Nutraceutical MS 622 Principle in Pharmacognosy 2 (2-0-6) MS 623 Principle of Medical Science Management 3 (3-0-9) MS 624 Regenerative Medicine 3 (3-0-9) Pharmacology MS 631 Principles of Pharmacology 2 (2-0-6) MS 632 Systemic Pharmacology 4 (4-0-12) MS 633 Seminar in Pharmacology 1 (1-0-3) Reproductive Medical Sciences (Lecture-Lab-SDL) MS 641 Advanced Reproductive Medical Sciences 3 (3-0-9) MS 642 Advanced Reproductive Technology 4 (1-6-9) MS 643 Special Topics in Reproductive Sciences 1 (1-0-3) Molecular Physiology and Biophysics MS 651 Advanced Medical Physiology 1 3 (3-0-9) MS 652 Advanced Medical Physiology 2 3 (3-0-9) MS 653 Experimental Methods in Physiology 1 (1-0-3) Biochemistry and Molecular Biology MS 661 Medical Biochemistry 3 (3-0-9) MS 662 Current Topics in Advanced Medical Biochemistry 3 (3-0-9) Applied Medical Sciences (Lecture-Lab-SDL) Applied Epidemiology and Health Research MS 771 Statistical Methods of Epidemiology and Health Research 3 (3-0-9) Psychological Health and Behavioral Sciences MS 781 Measurement in Health Research 3 (3-0-9) MS 782 Abnormal Behaviours and Mental Illness 3 (3-0-9)

8 Medical Informatics MS 791 Informatics in Medicine and Health 3 (3-0-9) MS 792 Database Design and Management 3 (3-0-9) Elective subjects The student must register elective subjects with the agreement of advisor for at least 3 credits. Basic Medical Sciences (Lecture-Lab-SDL) Cellular and Molecular Biology MS 617 Special Research Project 3 (0-9-3) MS 618 Current Topics in Cellular and Molecular Biology 3 (3-0-9) MS 619 Special Topics in Cellular and Molecular Biology 3 (3-0-9) Nutraceutical MS 627 Principle of Bioassay 3 (2-3-7) MS 628 Methods in Nutraceutical Sciences 3 (1-6-5) Pharmacology MS 637 Special Topics in Pharmacology 3 (3-0-9) Reproductive Medical Sciences The student can take a choice from the prescribed subjects opened in the Faculty of medicine or in other Faculties of Thammasat University with the consent of advisor or of the course coordinator. (Lecture-Lab-SDL) Molecular Physiology and Biophysics MS 657 Neurophysiology 3 (3-0-9) MS 658 Special Topics in Cardiovascular Physiology 3 (3-0-9) MS 659 Independent Study in Physiology 2 (2-0-6) Biochemistry and molecular Biology MS 667 Medical Nutrition 2 (2-0-6) MS 668 Molecular Genetics and Structural Biology in Medicine 3 (3-0-9) Applied Medical Sciences (Lecture-Lab-SDL) Epidemiology and Health Research MS 777 Special Topics in Epidemiology 3 (3-0-9) MS 778 Heath Outcome Research 3 (3-0-9) Psychological Health and Behavioral Sciences MS 787 Qualitative Research 3 (3-0-9) Medical Informatics MS 797 Decision Support Systems in Medicine and Health 3 (3-0-9) MS 798 System Analysis and Design in Medical Informatics 3 (3-0-9)

9 Apart from elective subjects above, the student can register any subject of graduate studies opened within or outside Thammasat University with an approval of their advisors Thesis The students have to select topics according to the field studied with an agreement of their advisors. MS 800 Thesis Study Plan For students who have bachelor degree or the one who transfers from doctoral level. 1 st year : 1 st semester Subjects Credits MS 600 Research Methodology and Ethics 2 MS 700 Applied Statistics 2 Related topics 4 Total 8 1 st year : 2 nd semester Subjects Credits Prescribed elective subjects 6 Elective subjects (general) 3 Total 9 2 nd year : 1 st semester Subjects Credits Thesis 12 Total 12 2 nd year : 2 nd semester Subjects Credits Thesis 10 Total 10 P.S.Total credits for the whole course must not be less than 39 credits Course descriptions 17.7 MS 600 Research Methodology and Ethics 2 (2-0-6) The subject consists of lectures on scientific knowledges of research methods and ethics in conducting research. Topics include data search through books, journals and information network, research design, formulation of hypotheses, data collection techniques, application of computer programs in data processing and analysis, statistical interpretation and conclusion, research report writing and critical appraisal of research publications. Topics of ethics in animal and human research include the consideration and evaluation of the necessity, risk and benefit of research, informed consent, legal aspects on human research and the necessity of an approval from human research ethical committee.

10 MS 613 Advanced Cellular Biology 3 (3-0-9) Prerequisite : MS 701 Cellular and Molecular Biology This course covers topics in advanced modern cell biology, starting with evolution of the cells, molecular structure of the organelles and cell organization, protein transport and processing, cytoskeletons, cell-cell communication and signal transduction, cell-extracellular matrix interaction, metabolism and energy system, cell cycle and cell growth, mechanism of stem cell differentiation, cell aging, cell death including cell technology in medical application. MS 614 Advanced Molecular Biology 3 (3-0-9) Prerequisite : MS 701 Cellular and Molecular Biology This subject includes detailed contents in advanced molecular biology, emphasizing on molecular biology of both prokaryotes and eukaryotes such as structures of DNA, RNA, gene and chromosome, mechanism of gene expression regulation, DNA repair, replication, transcription and translation, mutation and recombination, genetic engineering with its applications and new technology in molecular biology. MS 615 Basic Techniques in Cellular and Molecular Biology 2 (1-2-5) This laboratory course emphasizes on common laboratory techniques used in cell biology and molecular biology. These techniques include cell and tissue culture techniques, isolation and purification of DNA and RNA, analysis of DNA and RNA, polymerase chain reaction (PCR), construction of recombinant DNA and gene cloning, high throughput gene expression analysis and flow cytometry. Bioinformatics and computer applications in molecular biology is also included. MS 617 Special Research Project 3 (0-9-3) Small research projects in cellular and molecular biology that apply knowledges from course works, both theories and practicals to enhance research skills, knowledges and experiences in cellular and molecular biology are assigned. MS 618 Current Topics in Cellular and Molecular Biology 3 (3-0-9) Detailed consideration of the principle of cell differentiation, the developmental pathways from stem cells to specific cell types, signaling pathways involving in stem cell differentiation; the alteration of cell phenotypes accompanying carcinogenesis, the molecular mechanisms involving in carcinogenesis and the clinical applications of stem cell and cancer cell biology are to be studied. MS 619 Special Topics in Cellular and Molecular Biology 3 (3-0-9) Prerequisite : MS 701 Cellular and Molecular Biology This is an intensive advanced course which is literature-based, teaching students a particular topic in cell biology and molecular biology as well as the skill needed to access published data. The method of instruction will include introductory lectures as well as student presentations of selected papers from current literatures. Students are expected to participate in discussing the merits of each paper, its experimental approaches and results of the research. MS 622 Principle in Pharmacognosy 2 (2-0-6) This subject covers study on basic knowledges of secondary metabolites in plants, extraction and separation of these metabolites from plants including classification based on biosynthesis scheme, distribution in plant kingdom and different utilization in medical, pharmaceutical sciences and in daily life.

11 MS 623 Principle of Medical Science Management 3 (3-0-9) Study on the definition of work and work technology, placement of human resource in line with a suitable work technology, group dynamic, organizational decision, organization structure and goal preparation, market share analysis and forecasting, competitor, buyer and seller, market signal and response to market movement, financial management, fund raising, financial risk, short term and long term financial planning are included. MS 624 Regenerative Medicine 3 (3-0-9) Study on biomedicine, advanced medical technology and life style modification, drugs and supplements, detoxification, diets and diet supplement, sport medicine in the aspects of quality of life and human health, restoration, maintenance, and enhancement of tissue and organ functions, applications of in-vitro testing for drug metabolism and uptake, toxicity, pathogenicity and update medical diagnostic technology in regenerative medicine are arranged. MS 627 Principle of Bioassay 3 (2-3-7) Study on theory and laboratory techniques in bioassay testing for secondary metabolites in dietary supplement, cosmetics, drugs, pesticide and herbicide including toxicity testing are to be performed. MS 628 Methods in Nutraceutical Science 3 (1-6-5) Study on natural products and selection to meet objectives, the use of natural product database, sample preparation, preparation of crude extracts and analysis to find active ingredients are to be carried out. MS 631 Principles of Pharmacology 2 (2-0-6) General principles of Pharmacology and in-depth study of drug actions, emphasizing on pharmacokinetics and pharmacodynamics, absorption, distribution, metabolism and excretion, action and receptor concepts, adverse drug reactions, drug interactions and principle of toxicology are focused. MS 632 Systemic Pharmacology 4 (4-0-12) General principles of drug actions, physiological consequences of administration and principle of drug therapy are to be studied. MS 633 Seminar in Pharmacology 1 (1-0-3) This topic consists of review literature and evaluation, presentation and discussion of new trend in Pharmacology. MS 637 Special Topics in Pharmacology 3 (3-0-9) Prerequisite : with advices of advisors This subject consists of current issues in Pharmacology i.e. receptor pharmacology, clinical pharmacokinetics and pharmacoepidemiology. MS 641 Advanced Reproductive Medical Sciences 3 (3-0-9) This subject provides in-depth the study of changes in molecular, cellular and organ levels related to reproductive medicine. Mechanisms studied are gemetogensis, fertilization, implantation, embryo development and the endocrine changes of the fetus and placenta during pregnancy.

12 The course comprises of lectures, seminars and case discussions on care and management of patients with reproductive abnormalities i.e. menstrual problems, inferlility and chromosome abnormalities etc. MS 642 Advanced Reproductive Technology 4 (1-6-9) This subject comprises of lectures, seminars and workshops on hormonal assays, semen analysis, sperm preparation, oocyte mangement, in-vitro fertilization, micromanipulation, embryo culture, freezing and thawing processes, nuclear and cytoplasmic transfer, preimplantation genetic diagnosis (PGD) and stem cell study on theory, technologies and application. MS 643 Special Topics in Reproductive Sciences 1 (1-0-3) Prerequisite : with advisor s permission This subject is designed to encourage postgraduate students to study, with the approval and guidance of their advisors, topics of their interest in basic and advanced reproduction. This will strengthen their skills in searching for up-to-date knowledges, in reading and understanding international papers, in analyzing and evaluating the informations found in the papers, and also in presenting in a peer meeting what they have learnt. MS 651 Advanced Medical Physiology 1 3 (3-0-9) This course provides knowledges in advanced physiology of cells, tissues and organs of each system. It is designed to cover systemic functions such as the basis of the nervous system, the cardiovascular system, etc.,also focusing on the cooperation and integrated functions of those systems in order to maintain the homeostasis of the body. MS 652 Advanced Medical Physiology 2 3 (3-0-9) Prerequisite : MS 651 Advanced Medical Physiology 1 This subject is an in-depth study of the molecular and cellular functions which relate to the topic in Advanced Medical Physiology (MS 651). Topics include systemic and cellular integrated control system. Control of fluids and electrolytes balance are also focused. Current topics in recent research are assigned in class, followed by analysis of key points related to the contents. MS 653 Experimental Methods in Physiology 1 (1-0-3) This subject guides the students in building up their own physiological mind by way of lectures and demonstrations. The contents provided include classic animal experiments, common and advanced techniques in physiology. Some biochemical techniques are applied in physiological experiments. The students will learn how to handle all of these approaches to their research problems. MS 657 Neurophysiology 3 (3-0-9) Prerequisite: MS 651 Advanced Medical Physiology 1 and MS 652 Advanced Medical Physiology 2 Study of the nervous system functions, from the genesis of the bioelectrical potential, synaptic transmission, molecular mechanism of vesicle release of neurotransmitters, synthesis of each neurotransmitter, transportation, signal transduction of neurons, evoked potentials, etc., to the brain metabolism and its autoregulation. Sensory, motor and also autonomic nervous systems are described in detail. Higher brain functions and their relationship to behaviors are focused.

13 MS 658 Special Topics in Cardiovascular Physiology 3 (3-0-9) Prerequisite: MS 651 Advanced Medical Physiology 1 and MS 652 Advanced Medical Physiology 2 This subject consists of alternate sessions. First is a weekly presentation and discussion group in which graduate students review and discuss recently published scientific papers of major interest in cardiovascular physiology. The second is a session of their research in progress. Graduate students have an opportunity to improve their skills in topic presentation and strengthen their factual knowledge as well. Invited speakers and various experts will also share their experiences with the students. Advanced topic lectures are given throughout the course. MS 659 Independent Study in Physiology 2 (2-0-6) Prerequisite: MS 651 Advanced Medical Physiology 1 This course provides an opportunity for graduate students to work closely with their advisors. Topics in current research will be selected by to the students and a meeting or conference will be arranged. The graduate students will learn how to grasp the research idea and how to approach and solve research problems by themselves. Student s research potential should be strengthened based on their factual knowledge and total effort. MS 661 Medical Biochemistry 3 (3-0-9) The study of structure, function and metabolism of biomolecules in the human body, carbohydrate, lipid, protein and nucleic acid, enzymes, cofactors, homeostatic state including detoxification of waste products in human body, mechanism of genetic, information transtfer and regulation of gene expression are focused. MS 662 Current Topics in Advanced Medical Biochemistry 3 (3-0-9) Prerequisite: MS 661 Medical Biochemistry Lectures and discussions on current topics in medical biochemistry, including presentation on special topics are emphasized. MS 667 Medical Nutrition 2 (2-0-6) The nutritional requirement and assessment in both physiological and pathological status including preventive and therapeutic approaches of malnutrition in human are studied. MS 668 Molecular Genetics and Structural Biology in Medicine 3 (3-0-9) Prerequisite : MS 661 Medical Biochemistry The objective of this course is to provide the students with the principles and the basis of molecular and genetic processes of relevance to medicine. The course covers gene mutations, chromosome abnormalities, biological and clinical significance of genetic diversity, cancer genetics, structure of DNA and protein in detail, structure function relationship of DNA and proteins and their alterations leading to medical disorders, recombinant DNA technology and use of computational resources for studying molecular genetics and structural biology. MS 700 Applied Statisties 2 (2-0-6) The course covers the selection of descriptive and analytic statistics for biomedical and public health research, data collection and analysis. Topics also include probability distributions, sampling distributions, hypothesis testing, confidence intervals and significance tests using parametric and non-parametric methods, i.e. t-test, f-test and chi-square test. The

14 course also includes multiple and partial correlation analysis, regression analysis and the application of computer programs. MS 701 Cellular and Molecular Biology 3 (3-0-9) This subject describes an integrated introduction to the current concepts in cell biology and molecular biology. This course is taught as an integrated set of lectures, with an emphasis on cellular architecture, molecular basis of cellular compartmentalization, molecular basis of genetic information transfer, gene transcription and translation, protein trafficking, cell signaling, cell-matrix interaction, cell cycle, birth of life, evolution and biodiversity, cellular and molecular basis of diseases. Basic molecular techniques are also included. MS 702 Semimar in Medical Sciences 1 (1-0-3) This subject aims to encourage students to explore their interest topics from international journals in medical sciences under the supervision of advisors. The exploration of up-to-date papers will increase their potential skills in digesting papers including analysis and evaluation in order to gain insightful knowledge for further studies. In addition, presentation of the digested papers in a peer meeting will allow the students learn how to perform their speech in public and express their understanding of the paper throughly. MS 703 Epidemiology 3 (3-0-9) Epidemiology concepts, measures of occurrence of disease frequency, distributionsof disease frequency and risk assessment, errors and limitations of design in epidemiological study, selection of appropriate study design, definition and control of bias, confounding, and errors in epidemiological study, causal and inference in epidemiology and appraisal of epidemiological study are studied. MS 704 Seminar in Epidemiological and Health Research 1 (1-0-3) Study on self-directed learning in evaluation of various types of epidemiological and medical researches under supervision of advisor, skills in literature searching, reading, summarizing, and appraising state-of-the-art articles as well as presenting skill in academic congress are assigned. MS 771 Statistical Methods of Epidemiology and Health Research 3 (3-0-9) Study on descriptive statistics, common statistical methods used in analysis of epidemiological studies, stratified analysis to control confounding, definition and concepts of interaction, simple logistic regression, simple linear regression, interpretation of statistical analysis concerning types of study design and reporting statistical results are focused. MS 777 Special Topics in Epidemiology 3 (3-0-9) Choosing and discussion of current topics of clinical epidemiology or research design are aimed. Topics to be discussed include medical sciences, health economics, health policy related to epidemiology and applying epidemiology concept in health sciences. MS 778 Health Outcome Research 3 (3-0-9) Concepts of health outcomes including outcomes from patient perspective, clinical and economic outcomes are studied. Evaluation of health status and health-related quality of life, concepts in clinical trials, health service research, systematic reviews, and meta-analysis are assigned. Use of economic evaluation in health service research, cost effectiveness analysis, cost utility analysis, cost benefit analysis, interpretation and appraising of health researchs are also emphasized.

15 MS 781 Measurement in Health Research 3 (3-0-9) The course covers the concepts of measurement and the principles of selecting and developing research instrument and data collection tools. Students will learn how to evaluate the psychometric properties of an instrument. MS 782 Abnormal Behaviour and Mental Illness 3 (3-0-9) This course covers definitions and concepts of mental illnesses. Theories of abnormal behaviors and mental illnesses will be discussed. An overview of contributing factors such as social, developmental, biological, psychological and genetic factors are included. Psychiatric classification systems will be introduced. Psychiatric treatment, principles of psychopharmacology, and psychotherapy namely psychoanalysis, supportive psychotherapy, and cognitive behavioural therapy are also studied. MS 787 Qualitative Research 3 (3-0-9) The course covers principles and methods of qualitative research. Study designs in qualitative research and their characteristics are discussed. An introduction to qualitative data analysis is given. Applications of qualitative methods to health research will be emphasized. MS 791 Informatics in Medicine and Health 3 (3-0-9) This subject covers guideline and concept in medical informatics and health, techniques in using internet for medical data communication, usefulness of informatics in medical care and health quality and of ICD 10. MS 792 Database Design and Management 3 (3-0-9) Database management in health care services, micro and macro level, database for research work, design electronic case record form, data transfer and communication between hospital and clinic, data security, audit and trace system are included. MS 797 Decision Support Systems in Medicine and Health 3 (3-0-9) This subject consists of the following topics ; informations used in medical diagnostics, informations support decisions for treatment and curative, probability used for decision, EXPERT system, intelligence system and knowledge based. MS 798 System Analysis and Design in Medical Informatics 3 (3-0-9) Concept in system analysis for medical informatics, efficient informatics, integral knowledges in hardware, operating system and software are to be studied. MS 800 Thesis 22 The student conducts an advanced research in medical sciences and prepare a thesis under the supervision of his or her advisors. 18. Quality Assurance of the curriculum 18.1 Curriculum management The curriculum committee comprised of the director of Graduate Studies Program, teachers from various related subjects and educationists are responsible for curriculum management under supervision of the Graduate Studies Committee of the Faculty of Medicine, Thammasat University The curriculum are continuously evaluated and the results are analysed and used for revision, updating and development of the curriculum every five years.

16 Teaching is assessed by students and the results are analysed for revision and development of teachings and teaching process The teachers responsible for curriculum management, permanent staffs, invited teachers and consultants, advisors and thesis examiners are qualified according to regulation of Graduate Sutdies 2002 including revised issue 2006 of Thammasat University Quality control of thesis preparation is assigned. The students have to report their progress of thesis preparation to their advisors every 4 months Resources to support teaching See item 14 and Teachers development are carried out according to policy and strategies of the Faculty of Medicine, Thammasat University Support and advices for students The teachers are assigned for general consultation, giving advices on plan of study, etc. until their thesis advisors are arranged for all students Financial support and budget for student research works are also principally provided Evaluation of market requirement and user s satisfaction of our graduates Assessment of satisfaction of user of our graduates are to be performed for future development of curriculum and to fulfill market s requirements Advertisment of the curriculum is forwarded to personnels who work in the related health sciences area and require further graduate study deep into their interested problems. The studies will be either for the development of already established works or building up of new innovation in health sciences. 19. Curriculum Development 19.1 Indicators for educational standard and quality of this curriculum The contents and process of teaching are revised each year. The curriculum structure is revised every 5 years. Not less than 50% of the student registration must finish the course according to time frame of the curriculum. The satisfaction of the graduate s user must not be less than 70% of total graduates The research work from thesis of the students must be either published or submitted for publication in the accepted journals, academic publications or presented in the meeting or conferences with proceedings. The Faculty of Medicine determines to have curriculum evaluation performed according to the indicators mentioned above and the first evaluation will be processed in the year 2011.

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