Form 2118 R3.0: Hodgkin and Non-Hodgkin Lymphoma (LYM) Post-HCT Data
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- Felicity Nash
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1 Key Fields Sequence Number: Date Received: - - CIBMTR Center Number: CIBMTR Recipient ID: Date of HCT for which this form is being completed: - - HCT Type (Check all that apply): Autologous Allogeneic, unrelated Allogeneic, related Product Type: (Check all that apply) Bone marrow PBSC Single cord blood unit Multiple cord blood units Other product Visit Specify: 100 day 6 months 1 year 2 years > 2 years, Specify: Disease Assessment at the Time of Best Response to HCT Questions: Compared to the disease status prior to the preparative regimen, what was the best response to HCT since the date of the last report? (Include response to any therapy given for post-hct maintainance or consolidation, but exclude any therapy given for relapsed, persistent, or progressive disease.) Continued complete remission (CCR) (for patients transplanted in CR) Complete remission (CR) Partial remission (PR) - complete disappearance of all kwn disease. For typically FDG-avid lymphoma, a post-treatment residual mass of any size is permitted as long as it is PET negative. For variably FDG-avid lymphomas, all lymph des and dal masses must have regressed via CT to <1.5 cm (for des >1.5 cm before therapy) or <1 cm (for des 1.1 to 1.5 cm before therapy) - 50% reductions in greatest diameter of up to six largest dominant des or dal masses and new sites. For typically FDG-avid lymphomas, post-treatment PET should be positive in at least one site. For variably PET-avid lymphoma, use CT criteria. Stable disease (SD) - failure to attain CR, PR, or PD Progressive disease (PD) - increase by >50% of previously involved sites from nadir or any new lesion Not assessed 2 Was the date of best response previously reported? 3 Date assessed: Was the disease status assessed by molecular testing (e.g. PCR)? 5 Date assessed: - - Copyright(c) 2012 National Marrow Dor Program and Page 1 / 5
2 6 Was disease detected? 7 Was the status considered a disease relapse? 8 Was a PET (or PET/CT) scan performed? 9 Was the PET (or PET/CT) scan positive for lymphoma involvement at any disease site? Post-HCT Therapy Questions: Was therapy given since the date of the last report for reasons other than relapse or progressive disease? (Include any maintenance and consolidation therapy.) Specify therapy given: 11 Systemic therapy Specify therapy given: 12 Aldesleukin (interleukin-2, IL-2) 13 Alemtuzumab (Campath) 14 Lenalidomide (Revlimid) 15 Rituximab (Rituxan, MabThera) 16 Other systemic therapy 18 Radiation therapy 17 Specify other systemic therapy: Specify radiation site(s) 19 Mediastinum / chest 20 Other site 21 Specify other site: Copyright(c) 2012 National Marrow Dor Program and Page 2 / 5
3 22 Surgery 23 Other therapy 24 Specify other therapy: Disease Relapse or Progression Post-HCT Questions: Was a disease relapse or progression detected by molecular testing (e.g. PCR)? 26 Date assessed: Was a disease relapse or progression detected by cytogenetic testing (conventional or FISH)? 28 Was a disease relapse or progression detected via FISH? 29 Date assessed: Was a disease relapse or progression detected via conventional cytogenetics? 31 Date assessed: Was a disease relapse or progression detected by clinical / hematologic assessment? 33 Date assessed: Was a PET (or PET/CT) scan performed? 35 Date of most recent PET (or PET/CT) scan: Results of most recent PET (or PET/CT) scan Positive Negative indeterminate 37 Was the positive result considered a disease recurrence or progression? 38 Did the recipient have kwn dal involvement? 39 Specify the total number of dal regions involved one dal region two or more dal regions Unkwn 40 Was there any kwn extradal or splenic involvement? Unkwn Copyright(c) 2012 National Marrow Dor Program and Page 3 / 5
4 Specify site(s) of involvement: 41 Bone 42 Bone marrow 43 Brain 44 Cerebrospinal fluid (CSF) 45 Epidural space 46 Gastrointestinal (GI) tract 47 Kidney 48 Liver 49 Lung 50 Pleura 51 Skin 52 Spleen 53 Other site 54 Specify other site: Disease Status at the Time of Evaluation for This Reporting Period Questions: Was the disease status assessed by molecular testing (e.g. PCR)? 56 Date assessed: Was disease detected? Copyright(c) 2012 National Marrow Dor Program and Page 4 / 5
5 58 Was the disease status assessed by cytogenetic testing (conventional or FISH)? 59 Date assessed: Was disease detected? 61 Was the disease status assessed by clinical / hematologic assessment? 62 Date assessed: Was disease detected? 64 What is the current disease status? Continued complete remission (for patients transplanted in CR) Complete remission Partial remission - complete disappearance of all kwn disease. For typically FDG-avid lymphoma, a post-treatment residual mass of any size is permitted as long as it is PET negative. For variably FDG-avid lymphomas, all lymph des and dal masses must have regressed via CT to <1.5 cm (for des >1.5 cm before therapy) or <1 cm (for des 1.1 to 1.5 cm before therapy) - 50% reductions in greatest diameter of up to six largest dominant des or dal masses and new sites. For typically FDG-avid lymphomas, posttreatment PET should be positive in at least one site. For variably PET-avid lymphoma, use CT criteria. Stable disease - failure to attain CR, PR, or PD Progressive disease - increase by >50% of previously involved sites from nadir or any new lesion Relapse Not assessed 65 Date assessed: - - First Name: Last Name: address: Date: - - Copyright(c) 2012 National Marrow Dor Program and Page 5 / 5
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