Kidney Cancer OVERVIEW

Size: px
Start display at page:

Download "Kidney Cancer OVERVIEW"

Transcription

1 Kidney Cancer OVERVIEW Kidney cancer is the third most common genitourinary cancer in adults. There are approximately 54,000 new cancer cases each year in the United States, and the incidence of kidney cancer appears to be on the rise. Kidney cancer tends to occur most commonly in individuals over the age of 50 and is more common in men than in women. Most kidney cancers occur spontaneously, although some are associated with hereditary conditions, including von Hippel-Lindau disease and hereditary papillary renal cell carcinoma. Potential risk factors include cigarette smoking, obesity and high blood pressure. Although most growths that arise in the kidneys are cancers, about 30% of small kidney masses are benign. The most common types of benign kidney tumors are oncocytoma and angiomyolipoma. Renal cell carcinoma (RCC) is the most common type of kidney cancer. There are several sub-types of renal cell carcinoma. Clear cell (conventional) renal cell carcinoma is the most common sub-type and represents greater than 80% of renal cell carcinomas. Other sub-types include: Papillary renal cell carcinoma Chromophobe renal cell carcinoma Collecting duct renal cell carcinoma Medullary renal cell carcinoma Papillary and chromophobe variants of renal cell carcinoma may be less aggressive than clear cell renal cell carcinoma. Collecting duct and medullary sub-types are very aggressive cancers characterized by relatively poor outcomes. Local kidney cancer Approximately 60% of kidney cancers are diagnosed at a localized stage (cancer confined to kidney without evidence of spread). Localized cancers may be detected incidentally without causing symptoms or may be associated with hematuria (blood in the urine), flank pain or abdominal discomfort. Surgery is the most effective treatment, although in some cases (very small tumors or in patients who are not suitable candidates for surgery) other ablative techniques are available. Following surgical treatment, approximately 20% to 30% of patients with localized kidney cancers develop a reoccurrence. The overall 5-year survival for patients with localized kidney cancer is approximately 90%. Advanced kidney cancer Approximately 40% of kidney cancers are diagnosed at an advanced stage characterized by involvement of surrounding structures, spread to lymph nodes or metastasis to more distant sites. These tumors tend to be larger, and are more commonly high-grade and carry a higher risk of recurrence following treatment.

2 Because chemotherapy and radiation are ineffective against kidney cancer, surgery still plays an important role in the management of advanced kidney cancer, and may even be recommended in the setting of metastatic disease. Common sites of metastatic spread include the lung, bone and brain. The overall 5-year survival for regionally advanced kidney cancer (spread to adjacent structures and lymph nodes) is approximately 60% but decreases to 10% for distant metastatic disease. Signs & Symptoms Hematuria Gross Microscopic Abdominal or flank symptoms Pain Fullness or palpable mass Constitutional symptoms Fatigue Weight loss Fevers Other Hypertension (high blood pressure) Hypercalcemia (high calcium level in blood) Erythrocytosis (high blood counts) Liver dysfunction (elevation in liver enzymes) For many people, kidney cancer does not cause symptoms but is found incidentally on x-ray tests. In cases in which symptoms are present, the most common symptoms include hematuria (blood in the urine), abdominal discomfort or flank pain. Diagnosis Physical examination Abdominal CT scan Chest x-ray or CT scan Abdominal MRI (if indicated) Bone scan (if indicated) Head CT scan or MRI (if indicated) After taking a detailed medical history and performing a physical examination, the physician will order (or review previously performed) radiographic imaging. Most commonly, an abdominal CT scan with intravenous contrast is used to diagnose and stage kidney cancer. In cases in which contrast cannot be given because of allergy or renal dysfunction, a non-contrast CT scan or MRI can be performed. The appearance

3 of the kidney on radiographic imaging helps differentiate benign lesions from kidney cancer, provides important staging information, and helps determine the best treatment approach. Staging for kidney cancer Clinical staging is performed with Physical Examination, Abdominal CT scan, and Chest X-Ray. In cases of advanced or high-risk disease, additional testing such as MRI and Bone Scan may be necessary. The prognosis of kidney cancer is directly linked to the stage of disease. Staging is a process that demonstrates how far the cancer has spread. Both the treatment and prognosis (or outlook) for kidney cancer depend significantly on the stage of disease. T0 T1 T1a T1b T2 T3 T3a T3b T3c T4 N0 N1 N2 M0 M1 TNM SYSTEM Status No evidence of primary kidney tumor Tumor 7 cm or less limited to the kidney Tumor > 4 cm limited to the kidney Tumor >= 4 cm but <=7 cm limited to the kidney Tumor more than 7 cm limited to the kidney Tumor extends into major veins or invades perinephric tissue Tumor invades adrenal gland or perinephric tissue Tumor extends into renal vein or infra-diaphragmatic vena cava Tumor extends into supra-diaphragmatic vena cava Tumor invades beyond Gerota s fascia No regional lymph node metastasis Metastasis in a single regional lymph node Metastasis in multiple regional lymph nodes No distant metastases Distant metastasis Treatment Most kidney cancers are localized and can be managed with surgery. Treatment for localized kidney cancer include: Partial nephrectomy Radical nephrectomy Ablative therapy (radiofrequency ablation or cryosurgery) Active Surveillance (observation) Partial nephrectomy or removal of the tumor without removal of the entire kidney is often recommended in cases of smaller kidney tumors, in patients with a single kidney

4 or tumors in both kidneys, or in settings of impaired renal function. A partial nephrectomy may also be recommended in patients with Diabetes or Hypertension to preserve as much renal function as possible, even if the opposite kidney is normal. Currently, partial nephrectomy is most commonly used in tumors measuring 4 cm, although other factors impact whether or not a partial nephrectomy is possible or necessary. Partial nephrectomy can be performed either laparoscopically or with open surgery. In general, laparoscopic surgery is indicated for exophytic (the lesion protrudes from the kidney s surface) tumors. Open surgery, however, may be indicated in more complex cases (larger tumors, centrally located tumors or solitary kidneys). Laparoscopic and open partial nephrectomy are as effective as total or radical nephrectomy of early stage (stage T1) kidney cancer. Radical nephrectomy consists of removal of the entire kidney with the surrounding tissue and is most often used in cases in which a partial nephrectomy is not feasible because of tumor size or location. Radical nephrectomy is also the standard treatment for large tumors. For advanced stage kidney cancer, lymph node dissection, removal of other affected organs or structures, or tumor thrombectomy (removal of tumor thrombus from the vena cava) may be performed in conjunction with radical nephrectomy. Total nephrectomy may also be recommended in the setting of metastatic disease. Ablative therapies use radiofrequency energy and extremely low temperatures (cryoablation) to cause tissue destruction. Currently, the use of ablative therapies is limited to tumors >= 3 cm, peripherally located tumors because of limitations in the spread of the ablative effect. In addition, the effectiveness of ablative therapy compared to extirpative surgical therapy (partial and radical nephrectomy) is still under investigation. As a result, ablative therapy is most commonly used in older or medically unhealthy patients for whom the risk of surgical is too great. Active surveillance of small, early-stage, low-risk kidney cancers may be an option for those not interested in (or candidates for) surgery or ablative therapy, and consists of periodic re-imaging to determine the rate of tumor growth. In general, active surveillance may be appropriate in older individuals with small (>= 3 cm) kidney tumors for whom the risk of surgery is too great. Detection of uncharacteristic growth may prompt a decision regarding initiation of active treatment. Regionally advanced and metastatic kidney cancer presents a management challenge because renal cell carcinoma is not responsive to radiation therapy or traditional chemotherapy. Thus, surgery may still play a role, particularly in younger patients with adequate performance status. In cases of regional lymph node metastases or solitary distant metastases, such as a single lung nodule, radical nephrectomy combined with surgical removal of the metastases is often recommended as a standard treatment approach. Newer targeted agents known as tyrosine kinase inhibitors are being used to fight high-risk and metastatic kidney cancer. These agents act by targeting key regulatory pathways in cancer cells needs for cell survival. Tyrosine kinase inhibitors are being used in recurrent and metastatic disease, and are now being tested as an

5 adjunct to surgery in high-risk localized disease to decrease the chances of recurrence. Specifically, tyrosine kinase inhibitors when used in metastatic disease have yielded partial response in up to 15-25% of patients.

A912: Kidney, Renal cell carcinoma

A912: Kidney, Renal cell carcinoma A912: Kidney, Renal cell carcinoma General facts of kidney cancer Renal cell carcinoma, a form of kidney cancer that involves cancerous changes in the cells of the renal tubule, is the most common type

More information

Renal Cancer: Symptoms, diagnosis, pathology & prognosis

Renal Cancer: Symptoms, diagnosis, pathology & prognosis Renal Cancer: Symptoms, diagnosis, pathology & prognosis Mark Johnson Consultant Urological Surgeon Newcastle upon Tyne Hospitals NHS Foundation Trust Plan for today: How renal tumours present What investigations

More information

These rare variants often act aggressively and may respond differently to therapy than the more common prostate adenocarcinoma.

These rare variants often act aggressively and may respond differently to therapy than the more common prostate adenocarcinoma. Prostate Cancer OVERVIEW Prostate cancer is the second most common cancer diagnosed among American men, accounting for nearly 200,000 new cancer cases in the United States each year. Greater than 65% of

More information

Metastatic Renal Cell Carcinoma: Staging and Prognosis of Three Separate Cases.

Metastatic Renal Cell Carcinoma: Staging and Prognosis of Three Separate Cases. Metastatic Renal Cell Carcinoma: Staging and Prognosis of Three Separate Cases. Abstract This paper describes the staging, imaging, treatment, and prognosis of renal cell carcinoma. Three case studies

More information

Frequently Asked Questions about Kidney Cancer

Frequently Asked Questions about Kidney Cancer Patient Information English Frequently Asked Questions about Kidney Cancer The underlined terms are listed in the glossary. Here is an overview of the most frequently asked questions about kidney cancer.

More information

NEOPLASMS OF KIDNEY (RENAL CELL CARCINOMA) And RENAL PELVIS (TRANSITIONAL CELL CARCINOMA)

NEOPLASMS OF KIDNEY (RENAL CELL CARCINOMA) And RENAL PELVIS (TRANSITIONAL CELL CARCINOMA) NEOPLASMS OF KIDNEY (RENAL CELL CARCINOMA) And RENAL PELVIS (TRANSITIONAL CELL CARCINOMA) Merat Esfahani, MD Medical Oncologist, Hematologist Cancer Liaison Physician SwedishAmerican Regional Cancer Center

More information

Contact Maryann Verrillo Diane Shnitzler (703) 691-1805. Interventional Radiology Treatments for Kidney Cancer

Contact Maryann Verrillo Diane Shnitzler (703) 691-1805. Interventional Radiology Treatments for Kidney Cancer Interventional Radiology Treatments for Kidney Cancer FACT SHEET Contact Maryann Verrillo Diane Shnitzler (703) 691-1805 Kidney cancer is the eighth most common cancer in men and the tenth in women. 1

More information

RCC. RENAL CELL CARCINOMA the most common form of kidney cancer UNDERSTANDINGRCC

RCC. RENAL CELL CARCINOMA the most common form of kidney cancer UNDERSTANDINGRCC RCC RENAL CELL CARCINOMA the most common form of kidney cancer UNDERSTANDINGRCC RENAL CELL CARCINOMA ABOUT THIS GUIDE This guide will: Help you understand renal cell carcinoma (RCC) Provide information

More information

Genetics Gender plays a role in kidney cancer, as men are twice as likely as women to develop RCC

Genetics Gender plays a role in kidney cancer, as men are twice as likely as women to develop RCC What is kidney cancer? Renal cell carcinoma (RCC) is the most common kind of kidney cancer. 1 Normally, your kidneys filter your blood and excrete waste in urine. Although our kidneys are important, we

More information

Smoking and misuse of certain pain medicines can affect the risk of developing renal cell cancer.

Smoking and misuse of certain pain medicines can affect the risk of developing renal cell cancer. Renal cell cancer Renal cell cancer is a disease in which malignant (cancer) cells form in tubules of the kidney. Renal cell cancer (also called kidney cancer or renal adenocarcinoma) is a disease in which

More information

Liver Cancer What is the liver? What is liver cancer?

Liver Cancer What is the liver? What is liver cancer? Liver Cancer What is the liver? The liver is the largest internal organ in the body and is important in digesting food. The liver performs many other functions, including collecting and filtering blood

More information

Questions to Ask Before You Have a Kidney Removed for Kidney Cancer (Updated March 1, 2011)

Questions to Ask Before You Have a Kidney Removed for Kidney Cancer (Updated March 1, 2011) Questions to Ask Before You Have a Kidney Removed for Kidney Cancer (Updated March 1, 2011) If you have a small kidney cancer (less than 7 cm.), you have several treatment options available to you. These

More information

The TV Series. www.healthybodyhealthymind.com INFORMATION TELEVISION NETWORK

The TV Series. www.healthybodyhealthymind.com INFORMATION TELEVISION NETWORK The TV Series www.healthybodyhealthymind.com Produced By: INFORMATION TELEVISION NETWORK ONE PARK PLACE 621 NW 53RD ST BOCA RATON, FL 33428 1-800-INFO-ITV www.itvisus.com 2005 Information Television Network.

More information

Questions to Ask As You Learn More About Kidney Cancer

Questions to Ask As You Learn More About Kidney Cancer Questions to Ask As You Learn More About Kidney Cancer Now that you have been diagnosed with kidney cancer, it is important for you to understand your condition and your treatment options. Many patients

More information

Metastatic Cancer: Questions and Answers. Key Points

Metastatic Cancer: Questions and Answers. Key Points CANCER FACTS N a t i o n a l C a n c e r I n s t i t u t e N a t i o n a l I n s t i t u t e s o f H e a l t h D e p a r t m e n t o f H e a l t h a n d H u m a n S e r v i c e s Metastatic Cancer: Questions

More information

Kidney Cancer (Adult) - Renal Cell Carcinoma What is cancer?

Kidney Cancer (Adult) - Renal Cell Carcinoma What is cancer? Kidney Cancer (Adult) - Renal Cell Carcinoma What is cancer? The body is made up of trillions of living cells. Normal body cells grow, divide to make new cells, and die in an orderly way. During the early

More information

Kidney Cancer (Adult) - Renal Cell Carcinoma What is cancer?

Kidney Cancer (Adult) - Renal Cell Carcinoma What is cancer? Kidney Cancer (Adult) - Renal Cell Carcinoma What is cancer? The body is made up of hundreds of millions of living cells. Normal body cells grow, divide, and die in an orderly fashion. During the early

More information

KIDNEY CANCER (ADULT) - RENAL CELL CARCINOMA

KIDNEY CANCER (ADULT) - RENAL CELL CARCINOMA KIDNEY CANCER (ADULT) - RENAL CELL CARCINOMA What is cancer? Cancer develops when cells in a part of the body begin to grow out of control. Although there are many kinds of cancer, they all start because

More information

Renal Cell Carcinoma. Background 1. General information. Pathophysiology 1. Pathology of disease. Diagnostics 1. History

Renal Cell Carcinoma. Background 1. General information. Pathophysiology 1. Pathology of disease. Diagnostics 1. History Renal Cell Carcinoma Background 1. General information o Accounts for 2-3 % of all malignancies o 5 variants 75-85% clear cell tumors 12-14% chromophilic 4-6% chromophobic 2-4% oncocytic 1% collecting

More information

THYROID CANCER. I. Introduction

THYROID CANCER. I. Introduction THYROID CANCER I. Introduction There are over 11,000 new cases of thyroid cancer each year in the US. Females are more likely to have thyroid cancer than men by a ratio of 3:1, and it is more common in

More information

Diagnosis and Prognosis of Thyroid Cancer

Diagnosis and Prognosis of Thyroid Cancer Main Page Risk Factors Reducing Your Risk Screening Symptoms Diagnosis Treatment Overview Chemotherapy Radiation Therapy Surgical Procedures Medications Lifestyle Changes Living With Thyroid Cancer Talking

More information

Four Important Facts about Kidney Cancer

Four Important Facts about Kidney Cancer Volume Article.13-11 Publish Date: 24th June 2013 Author(s): MPUH - CRS Team Four Important Facts about Kidney Cancer ARTICLE hhh Muljibhai Patel Urological Hospital (MPUH) Centre For Robotic Surgery (CRS)

More information

Louisiana Cancer Facts & Figures Kidney Cancer 2016

Louisiana Cancer Facts & Figures Kidney Cancer 2016 Louisiana Cancer Facts & Figures Kidney Cancer 2016 Louisiana Tumor Registry April 2016 1 Louisiana Tumor Registry Cancer Facts & Figures, Kidney Cancer 2016 Contents Contents: Table of Contents Introduction

More information

Metastatic Cervical Cancer s/p Radiation Therapy, Radical Hysterectomy and Attempted Modified Internal Hemipelvectomy

Metastatic Cervical Cancer s/p Radiation Therapy, Radical Hysterectomy and Attempted Modified Internal Hemipelvectomy Metastatic Cervical Cancer s/p Radiation Therapy, Radical Hysterectomy and Attempted Modified Internal Hemipelvectomy Sarah Hutto,, MSIV Marc Underhill, M.D. January 27, 2009 Past History 45 yo female

More information

Pancreatic Cancer. What does the pancreas do? What is cancer?

Pancreatic Cancer. What does the pancreas do? What is cancer? Pancreatic Cancer Pancreatic cancer mainly occurs in people over 60. If it is diagnosed at an early stage, then an operation to remove the cancer followed by chemotherapy with or without radiation therapy

More information

Case Number: RT2009-124(M) Potential Audiences: Intent Doctor, Oncology Special Nurse, Resident Doctor

Case Number: RT2009-124(M) Potential Audiences: Intent Doctor, Oncology Special Nurse, Resident Doctor Renal Cell Carcinoma of the Left Kidney Post Radical Surgery with pt4 Classification with Multiple Lung and Single Brain Metastases: the Role and Treatment Consideration of Radiotherapy Case Number: RT2009-124(M)

More information

Frequently Asked Questions About Ovarian Cancer

Frequently Asked Questions About Ovarian Cancer Media Contact: Gerri Gomez Howard Cell: 303-748-3933 gerri@gomezhowardgroup.com Frequently Asked Questions About Ovarian Cancer What is ovarian cancer? Ovarian cancer is a cancer that forms in tissues

More information

DIAGNOSIS OF PROSTATE CANCER

DIAGNOSIS OF PROSTATE CANCER DIAGNOSIS OF PROSTATE CANCER Determining the presence of prostate cancer generally involves a series of tests and exams. Before starting the testing process, the physician will ask questions about the

More information

Localized Kidney Cancer

Localized Kidney Cancer Patient Information English 3 Localized Kidney Cancer The underlined terms are listed in the glossary. If you are diagnosed with localized kidney cancer, your doctor can recommend treating the cancer with

More information

Diagnosis and Prognosis of Pancreatic Cancer

Diagnosis and Prognosis of Pancreatic Cancer Main Page Risk Factors Reducing Your Risk Screening Symptoms Diagnosis Treatment Overview Chemotherapy Radiation Therapy Surgical Procedures Lifestyle Changes Managing Side Effects Talking to Your Doctor

More information

I've Just Been Diagnosed. with Kidney Cancer: What s Next?

I've Just Been Diagnosed. with Kidney Cancer: What s Next? I've Just Been Diagnosed with Cancer: What s Next? Table of Contents Introduction Message from a Survivor What are the s and What is Their Function? What is Cancer? What are the Types of Cancer? What are

More information

Understanding Kidney Cancer

Understanding Kidney Cancer Understanding Kidney Cancer Guest Expert: Harriet, MD Associate Professor of Medical Oncology www.wnpr.org www.yalecancercenter.org Welcome to Yale Cancer Center Answers with Drs. Ed and Francine Foss,

More information

Lung cancer is not just one disease. There are two main types of lung cancer:

Lung cancer is not just one disease. There are two main types of lung cancer: 1. What is lung cancer? 2. How common is lung cancer? 3. What are the risk factors for lung cancer? 4. What are the signs and symptoms of lung cancer? 5. How is lung cancer diagnosed? 6. What are the available

More information

LYMPHOMA IN DOGS. Diagnosis/Initial evaluation. Treatment and Prognosis

LYMPHOMA IN DOGS. Diagnosis/Initial evaluation. Treatment and Prognosis LYMPHOMA IN DOGS Lymphoma is a relatively common cancer in dogs. It is a cancer of lymphocytes (a type of white blood cell) and lymphoid tissues. Lymphoid tissue is normally present in many places in the

More information

Renal Cell Carcinoma The New Frontier (To boldly go... ) Sean A. Pierre, MD, RCPSC (Urology)

Renal Cell Carcinoma The New Frontier (To boldly go... ) Sean A. Pierre, MD, RCPSC (Urology) The New Frontier (To boldly go... ) Sean A. Pierre, MD, RCPSC (Urology) QUEENSWAY CARLETON HOSPITAL DIVISION OF UROLOGY NEPEAN, ON, CANADA Disclosures None Objectives Advances in the field of Renal Cell

More information

Breast Cancer: from bedside and grossing room to diagnoses and beyond. Adriana Corben, M.D.

Breast Cancer: from bedside and grossing room to diagnoses and beyond. Adriana Corben, M.D. Breast Cancer: from bedside and grossing room to diagnoses and beyond Adriana Corben, M.D. About breast anatomy Breasts are special organs that develop in women during puberty when female hormones are

More information

Kidney Cancer Understanding your diagnosis

Kidney Cancer Understanding your diagnosis Kidney Cancer Understanding your diagnosis Let s Make Cancer History 1 888 939-3333 cancer.ca Kidney Cancer Understanding your diagnosis When you first hear that you have cancer you may feel alone and

More information

Something Old, Something New.

Something Old, Something New. Something Old, Something New. Michelle A. Fajardo, D.O. Loma Linda University Medical Center Clinical Presentation 6 year old boy, presented with hematuria Renal mass demonstrated by ultrasound & CT scan

More information

Lung Cancer: Diagnosis, Staging and Treatment

Lung Cancer: Diagnosis, Staging and Treatment PATIENT EDUCATION patienteducation.osumc.edu Lung Cancer: Diagnosis, Staging and Treatment Cancer starts in our cells. Cells are the building blocks of our tissues. Tissues make up the organs of the body.

More information

Types of surgery for kidney cancer

Types of surgery for kidney cancer Useful information for cancer patients Contents This information is about the different operations that you may have for kidney cancer. Surgery can be used to treat almost any stage of kidney cancer. There

More information

[ Testicular Cancer Treatment In India at

[ Testicular Cancer Treatment In India at 2011 We care health Services Pankaj nagpal [ Testicular Cancer Treatment In India at Mumbai At Low cost] [Type the abstract of the document here. The abstract is typically a short summary of the contents

More information

95% of childhood kidney cancer cases are Wilms tumours. Childhood kidney cancer is extremely rare, with only 90 cases a year in

95% of childhood kidney cancer cases are Wilms tumours. Childhood kidney cancer is extremely rare, with only 90 cases a year in James Whale Fund for Kidney Cancer Childhood kidney cancer factsheet Kidney cancer rarely afflicts children and about 90 paediatric cases are diagnosed in the UK each year. About 75% of childhood kidney

More information

Liver Cancer And Tumours

Liver Cancer And Tumours Liver Cancer And Tumours What causes liver cancer? Many factors may play a role in the development of cancer. Because the liver filters blood from all parts of the body, cancer cells from elsewhere can

More information

This handout is for informational purposes only. Talk with your doctor or health care team if you have any questions about your care.

This handout is for informational purposes only. Talk with your doctor or health care team if you have any questions about your care. PATIENT EDUCATION patienteducation.osumc.edu What is the esophagus? The esophagus (food pipe) is a tube that connects your throat to your stomach. It is about 10 inches long and runs behind your trachea

More information

A PATIENT S GUIDE TO ABLATION THERAPY

A PATIENT S GUIDE TO ABLATION THERAPY A PATIENT S GUIDE TO ABLATION THERAPY THE DIVISION OF VASCULAR/INTERVENTIONAL RADIOLOGY THE ROBERT WOOD JOHNSON UNIVERSITY HOSPITAL Treatment options for patients with cancer continue to expand, providing

More information

Table 16a Multiple Myeloma Average Annual Number of Cancer Cases and Age-Adjusted Incidence Rates* for 2002-2006

Table 16a Multiple Myeloma Average Annual Number of Cancer Cases and Age-Adjusted Incidence Rates* for 2002-2006 Multiple Myeloma Figure 16 Definition: Multiple myeloma forms in plasma cells that are normally found in the bone marrow. 1 The plasma cells grow out of control and form tumors (plasmacytoma) or crowd

More information

What is kidney cancer?

What is kidney cancer? Kidney Cancer (Adult) - Renal Cell Carcinoma Overview This overview is based on the more detailed information in our document, Kidney Cancer (Adult) Renal Cell Carcinoma. You can get this document and

More information

.org. Metastatic Bone Disease. Description

.org. Metastatic Bone Disease. Description Metastatic Bone Disease Page ( 1 ) Cancer that begins in an organ, such as the lungs, breast, or prostate, and then spreads to bone is called metastatic bone disease (MBD). More than 1.2 million new cancer

More information

A practical guide for patients and families.

A practical guide for patients and families. 2012 Edition The Presents... We Have Kidney Cancer A practical guide for patients and families. KidneyCancer.org F O R E W O R D It is with pleasure that I present the latest edition of We Have Kidney

More information

Table 24a Thyroid Cancer Average Annual Number of Cancer Cases and Age-Adjusted Incidence Rates* for

Table 24a Thyroid Cancer Average Annual Number of Cancer Cases and Age-Adjusted Incidence Rates* for Thyroid Cancer Figure 24 Definition: Thyroid cancer starts in the thyroid gland. 1 The thyroid is made up of two main types of cells, thyroid follicular cells and parafollicular cells. 1 Different types

More information

Small Cell Lung Cancer

Small Cell Lung Cancer Small Cell Lung Cancer Types of Lung Cancer Non-small cell carcinoma (NSCC) (87%) Adenocarcinoma (38%) Squamous cell (20%) Large cell (5%) Small cell carcinoma (13%) Small cell lung cancer is virtually

More information

Lung Cancer: Diagnosis, Staging and Treatment

Lung Cancer: Diagnosis, Staging and Treatment PATIENT EDUCATION patienteducation.osumc.edu Lung Cancer: Diagnosis, Staging and Treatment Cancer begins in our cells. Cells are the building blocks of our tissues. Tissues make up the organs of the body.

More information

Mesothelioma. 1995-2013, The Patient Education Institute, Inc. www.x-plain.com ocft0101 Last reviewed: 03/21/2013 1

Mesothelioma. 1995-2013, The Patient Education Institute, Inc. www.x-plain.com ocft0101 Last reviewed: 03/21/2013 1 Mesothelioma Introduction Mesothelioma is a type of cancer. It starts in the tissue that lines your lungs, stomach, heart, and other organs. This tissue is called mesothelium. Most people who get this

More information

Clinical Management Guideline Management of locally advanced or recurrent Renal cell carcinoma. Protocol for Planning and Treatment

Clinical Management Guideline Management of locally advanced or recurrent Renal cell carcinoma. Protocol for Planning and Treatment Protocol for Planning and Treatment The process to be followed in the management of: LOCALLY ADVANCED OR METASTATIC RENAL CELL CARCINOMA Patient information given at each stage following agreed information

More information

9. Discuss guidelines for follow-up post-thyroidectomy for cancer (labs/tests) HH

9. Discuss guidelines for follow-up post-thyroidectomy for cancer (labs/tests) HH 9. Discuss guidelines for follow-up post-thyroidectomy for cancer (labs/tests) HH Differentiated thyroid cancer expresses the TSH receptor on the cell membrane and responds to TSH stimulation by increasing

More information

Primary -Benign - Malignant Secondary

Primary -Benign - Malignant Secondary TUMOURS OF THE LUNG Primary -Benign - Malignant Secondary The incidence of lung cancer has been increasing almost logarithmically and is now reaching epidemic levels. The overall cure rate is very low

More information

Medullary Renal Cell Carcinoma Case Report

Medullary Renal Cell Carcinoma Case Report Bahrain Medical Bulletin, Vol. 27, No. 4, December 2005 Medullary Renal Cell Carcinoma Case Report Mohammed Abdulla Al-Tantawi MBBCH, CABS* Abdul Amir Issa MBBCH, CABS*** Mohammed Abdulla MBBCH, CABS**

More information

Thyroid Cancer. This reference summary will help you better understand what thyroid cancer is and what treatment options are available.

Thyroid Cancer. This reference summary will help you better understand what thyroid cancer is and what treatment options are available. Thyroid Cancer Introduction The thyroid is a gland in the neck. Thyroid cancer is a common type of cancer. It accounts for 1% to 5% of cancer cases worldwide. As medical technology advances, more cases

More information

Breast cancer. A guide for journalists on breast cancer and its treatment

Breast cancer. A guide for journalists on breast cancer and its treatment Breast cancer A guide for journalists on breast cancer and its treatment Contents Contents 2 3 Section 1: Breast Cancer 4 i. What is breast cancer? 4 ii. Types of breast cancer 4 iii. Causes and risk factors

More information

Brain Cancer. This reference summary will help you understand how brain tumors are diagnosed and what options are available to treat them.

Brain Cancer. This reference summary will help you understand how brain tumors are diagnosed and what options are available to treat them. Brain Cancer Introduction Brain tumors are not rare. Thousands of people are diagnosed every year with tumors of the brain and the rest of the nervous system. The diagnosis and treatment of brain tumors

More information

Gallbladder cancer is a disease in which malignant (cancer) cells form in the tissues of the gallbladder.

Gallbladder cancer is a disease in which malignant (cancer) cells form in the tissues of the gallbladder. Gallbladder cancer Gallbladder cancer is a disease in which malignant (cancer) cells form in the tissues of the gallbladder. Gallbladder cancer is a rare disease in which malignant (cancer) cells are found

More information

OBJECTIVES By the end of this segment, the community participant will be able to:

OBJECTIVES By the end of this segment, the community participant will be able to: Cancer 101: Cancer Diagnosis and Staging Linda U. Krebs, RN, PhD, AOCN, FAAN OCEAN Native Navigators and the Cancer Continuum (NNACC) (NCMHD R24MD002811) Cancer 101: Diagnosis & Staging (Watanabe-Galloway

More information

Cancer of the Cervix

Cancer of the Cervix Cancer of the Cervix WOMENCARE A Healthy Woman is a Powerful Woman (407) 898-1500 A woman's cervix (the opening of the uterus) is lined with cells. Cancer of the cervix occurs when those cells change,

More information

RENAL CANCER PATHOLOGY WHAT REALLY MATTERS? STEWART FLEMING UNIVERSITY OF DUNDEE

RENAL CANCER PATHOLOGY WHAT REALLY MATTERS? STEWART FLEMING UNIVERSITY OF DUNDEE RENAL CANCER PATHOLOGY WHAT REALLY MATTERS? STEWART FLEMING UNIVERSITY OF DUNDEE MAJOR PARADIGM SHIFT IN EARLY 1990S IN UNDERSTANDING RENAL CANCER Molecular differential pathology of renal cell tumours

More information

Understanding Metastatic Disease

Understanding Metastatic Disease Supported by an unrestricted educational grant from Pfizer Understanding Metastatic Disease Metastatic disease or metastases are phrases that mean the same as Secondary cancer. This means that the cancer

More information

CMScript. Member of a medical scheme? Know your guaranteed benefits! Issue 7 of 2014

CMScript. Member of a medical scheme? Know your guaranteed benefits! Issue 7 of 2014 Background CMScript Member of a medical scheme? Know your guaranteed benefits! Issue 7 of 2014 Prostate cancer is second only to lung cancer as the leading cause of cancer-related deaths in men. It is

More information

About the kidneys and kidney cancer

About the kidneys and kidney cancer About the kidneys and kidney cancer This information is an extract from the booklet Understanding kidney cancer. You may find the full booklet helpful. We can send you a free copy see page 5. The kidneys

More information

AJCC 癌症分期及臨床應用 中山醫學大學附設醫院 胸腔外科姚忠瑾醫師 ( 六 )

AJCC 癌症分期及臨床應用 中山醫學大學附設醫院 胸腔外科姚忠瑾醫師 ( 六 ) AJCC 癌症分期及臨床應用 中山醫學大學附設醫院 胸腔外科姚忠瑾醫師 2014.04.12( 六 ) The Thyroid: Anatomy Located in the front of the neck just below the larynx (voicebox) Gland with two lobes, one on each side of the windpipe, joined

More information

Guidelines on Renal Cell

Guidelines on Renal Cell Guidelines on Renal Cell Carcinoma (Text update April 2010) B. Ljungberg (Chairman), N. Cowan, D.C. Hanbury, M. Hora, M.A. Kuczyk, A.S. Merseburger, P.F.A. Mulders, J-J. Patard, I.C. Sinescu Eur Urol 2001

More information

Introduction Breast cancer is cancer that starts in the cells of the breast. Breast cancer happens mainly in women. But men can get it too.

Introduction Breast cancer is cancer that starts in the cells of the breast. Breast cancer happens mainly in women. But men can get it too. Male Breast Cancer Introduction Breast cancer is cancer that starts in the cells of the breast. Breast cancer happens mainly in women. But men can get it too. Many people do not know that men can get breast

More information

Neuroendocrine Tumors

Neuroendocrine Tumors Neuroendocrine Tumors Neuroendocrine tumors arise from cells that release a hormone in response to a signal from the nervous system. Neuro refers to the nervous system. Endocrine refers to the hormones.

More information

Analysis of Prostate Cancer at Easter Connecticut Health Network Using Cancer Registry Data

Analysis of Prostate Cancer at Easter Connecticut Health Network Using Cancer Registry Data The 2014 Cancer Program Annual Public Reporting of Outcomes/Annual Site Analysis Statistical Data from 2013 More than 70 percent of all newly diagnosed cancer patients are treated in the more than 1,500

More information

Men s Health Testicular Cancer Colon Cancer

Men s Health Testicular Cancer Colon Cancer Men s Health Testicular Cancer Colon Cancer Testicular Cancer Testicular Cancer Facts Accounts for 1% of cancers in men. About 8,000 men are diagnosed with testicular cancer each year. Only 370 deaths

More information

Treatment Guide Lung Cancer Management

Treatment Guide Lung Cancer Management Treatment Guide Lung Cancer Management The Chest Cancer Center at Cleveland Clinic, which includes specialists from the Respiratory Institute, Taussig Cancer Institute and Miller Family Heart & Vascular

More information

Renal Cancer. Measurability of Quality Performance Indicators Version 1.1

Renal Cancer. Measurability of Quality Performance Indicators Version 1.1 Renal Cancer Measurability of Quality Permance Indicators Version 1.1 To be read in conjunction with: Renal Cancer Clinical Quality Permance Indicators Engagement Document v1.0 Renal Cancer Data Definitions

More information

The causes of kidney cancer are unknown. However, there are several factors that may increase your risk including:

The causes of kidney cancer are unknown. However, there are several factors that may increase your risk including: Kidney cancer Summary Kidney cancer is more common in people over the age of 55 years. Most kidney cancers are found when the doctor is checking for something else. A person is usually able to live quite

More information

Lung Cancer Treatment Guidelines

Lung Cancer Treatment Guidelines Updated June 2014 Derived and updated by consensus of members of the Providence Thoracic Oncology Program with the aid of evidence-based National Comprehensive Cancer Network (NCCN) national guidelines,

More information

PRINCESS MARGARET CANCER CENTRE CLINICAL PRACTICE GUIDELINES

PRINCESS MARGARET CANCER CENTRE CLINICAL PRACTICE GUIDELINES PRINCESS MARGARET CANCER CENTRE CLINICAL PRACTICE GUIDELINES GENITOURINARY RENAL CELL CARCINOMA GU Site Group Renal Cell Carcinoma Date Guideline Created: June 2012 Author: Dr. Charles Catton 1. INTRODUCTION

More information

Early Prostate Cancer: Questions and Answers. Key Points

Early Prostate Cancer: Questions and Answers. Key Points CANCER FACTS N a t i o n a l C a n c e r I n s t i t u t e N a t i o n a l I n s t i t u t e s o f H e a l t h D e p a r t m e n t o f H e a l t h a n d H u m a n S e r v i c e s Early Prostate Cancer:

More information

See MP/H rules on the slides if you do not have your manual.

See MP/H rules on the slides if you do not have your manual. Quiz 1 1. Which of the following statements about the incidence of melanoma in the US over the last 30 years is true? a. Melanoma incidences have been going down for both men and women. b. Melanoma incidences

More information

Active surveillance: Closely monitoring a patient's condition but withholding treatment until symptoms appear or change.

Active surveillance: Closely monitoring a patient's condition but withholding treatment until symptoms appear or change. Glossary of Terms Relating to Kidney Cancer Abdomen: The area of the body that contains the pancreas, stomach, intestines, liver, gallbladder, and other organs. The kidneys are located behind the abdominal

More information

Uterine sarcomas are very rare. They are responsible for only 1 to 5 percent of all malignancies

Uterine sarcomas are very rare. They are responsible for only 1 to 5 percent of all malignancies EVERYONE S GUIDE FOR CANCER THERAPY Malin Dollinger, MD, Ernest H. Rosenbaum, MD, Margaret Tempero, MD, and Sean Mulvihill, MD 4 th Edition 2001 Uterus: Uterine Sarcomas Jeffrey L. Stern, MD Uterine sarcomas

More information

SEMESTER VI 3 RD YEAR PATHOLOGY KIDNEY TUMORS

SEMESTER VI 3 RD YEAR PATHOLOGY KIDNEY TUMORS SEMESTER VI 3 RD YEAR PATHOLOGY KIDNEY TUMORS LEARNING OBJECTIVES At the end of the lecture, students should be able to: Know the pathology of renal tumors. RENAL TUMORS RENAL PAPILLARY ADENOMA Common

More information

Kidney Cancer. Understanding your diagnosis

Kidney Cancer. Understanding your diagnosis Kidney Cancer Understanding your diagnosis Kidney Cancer Understanding your diagnosis When you first hear that you have cancer, you may feel alone and afraid. You may be overwhelmed by the large amount

More information

Renal Cysts What should I do now?

Renal Cysts What should I do now? Renal Cysts What should I do now? Dr Edmund Chiong Asst. Professor & Consultant Department of Urology National University Hospital What are renal cysts? Fluid-filled structures in the kidney that are not

More information

Oncology. Objectives. Cancer Nomenclature. Cancer is a disease of the cell Cancer develops when certain cells begin to grow out of control

Oncology. Objectives. Cancer Nomenclature. Cancer is a disease of the cell Cancer develops when certain cells begin to grow out of control Oncology Objectives Describe the etiology and pathophysiological mechanisms of cancer Discuss medical and family history findings relevant to cancer Identify general signs and symptoms associated with

More information

Facing Kidney Surgery? Learn about minimally invasive da Vinci Surgery

Facing Kidney Surgery? Learn about minimally invasive da Vinci Surgery Facing Kidney Surgery? Learn about minimally invasive da Vinci Surgery The Condition: Kidney Cancer Your kidneys are two, fist-sized organs located behind the abdomen on each side of your spine. Kidneys

More information

There are a number of other carcinogens (cancer causing agents) that are believed to be associated with lung cancer, and are reviewed elsewhere.

There are a number of other carcinogens (cancer causing agents) that are believed to be associated with lung cancer, and are reviewed elsewhere. Lung Cancer What is cancer? First, some background on the way the body is built. Organs, like the heart, liver, and lung, are made up of tissues, such as blood vessels and muscle. Tissues, in turn, are

More information

2003 2007 STUDIES OF QUALITY OUTCOMES /BRAIN TUMORS ASTROCYTOMA. Introduction

2003 2007 STUDIES OF QUALITY OUTCOMES /BRAIN TUMORS ASTROCYTOMA. Introduction 2003 2007 STUDIES OF QUALITY OUTCOMES /BRAIN TUMORS ASTROCYTOMA Introduction Astrocytoma represents an important subtype of glial tumors. Its name derives from the fact that the involved cells have the

More information

Metastatic Breast Cancer...

Metastatic Breast Cancer... DIAGNOSIS: Metastatic Breast Cancer... What Does It Mean For You? A diagnosis of metastatic breast cancer can be frightening. It raises many questions and reminds us of days past when cancer was such a

More information

New Surgeries Provide More Hope for Kidney Cancer Patients Local Surgeon Helps Lead New Fight Against Kidney Cancer

New Surgeries Provide More Hope for Kidney Cancer Patients Local Surgeon Helps Lead New Fight Against Kidney Cancer Story highlights and opportunities: Kidney cancer symptoms can be mistaken for menopause. (Patient example below.) Kidney cancer can be diagnosed incidentally, when being treated for something else. (Patient

More information

Corporate Medical Policy

Corporate Medical Policy Corporate Medical Policy File Name: Origination: Last CAP Review: Next CAP Review: Last Review: microwave_tumor_ablation 12/2011 11/2015 11/2016 11/2015 Description of Procedure or Service Microwave ablation

More information

Prostate Cancer In-Depth

Prostate Cancer In-Depth Prostate Cancer In-Depth Introduction Prostate cancer is the most common visceral malignancy among American men. In the year 2003, there are expected to be 220,000 new cases and nearly 29,000 deaths in

More information

(Osteosarcoma; Chondrosarcoma; Ewing s Sarcoma; Fibrosarcoma; Malignant Fibrous Histiocytoma; Primary Lymphoma of Bone; Giant Cell Tumor; Chordoma)

(Osteosarcoma; Chondrosarcoma; Ewing s Sarcoma; Fibrosarcoma; Malignant Fibrous Histiocytoma; Primary Lymphoma of Bone; Giant Cell Tumor; Chordoma) Bone Cancer (Osteosarcoma; Chondrosarcoma; Ewing s Sarcoma; Fibrosarcoma; Malignant Fibrous Histiocytoma; Primary Lymphoma of Bone; Giant Cell Tumor; Chordoma) by Krisha McCoy, MS En Español (Spanish Version)

More information

Imaging Diagnosis and Staging of Lung Cancer By Mamdouh Mahfouz MD Radio diagnosis Cairo University

Imaging Diagnosis and Staging of Lung Cancer By Mamdouh Mahfouz MD Radio diagnosis Cairo University Imaging Diagnosis and Staging of Lung Cancer By Mamdouh Mahfouz MD Radio diagnosis Cairo University mamdouh.m5@gmail.com www.ssregypt.com Lung Cancer The most common cause of deaths worldwide Cigarette

More information

LIVER CANCER AND TUMOURS

LIVER CANCER AND TUMOURS LIVER CANCER AND TUMOURS LIVER CANCER AND TUMOURS Healthy Liver Cirrhotic Liver Tumour What causes liver cancer? Many factors may play a role in the development of cancer. Because the liver filters blood

More information

Understanding. Pancreatic Cancer

Understanding. Pancreatic Cancer Understanding Pancreatic Cancer Understanding Pancreatic Cancer The Pancreas The pancreas is an organ that is about 6 inches long. It s located deep in your belly between your stomach and backbone. Your

More information

PANCREATIC CANCER. Two different categories of cancer can affect the pancreas: Exocine and Endocrine cancers

PANCREATIC CANCER. Two different categories of cancer can affect the pancreas: Exocine and Endocrine cancers PANCREATIC CANCER INTRODUCTION More than 42,000 Americans develop cancer of the pancreas each year; it is the fourth leading cause of cancer-related death in the United States. Two different categories

More information

Us TOO University Presents: Understanding Diagnostic Testing

Us TOO University Presents: Understanding Diagnostic Testing Us TOO University Presents: Understanding Diagnostic Testing for Prostate Cancer Patients Today s speaker is Manish Bhandari, MD Program moderator is Pam Barrett, Us TOO International Made possible by

More information

Lung Cancer. This reference summary will help you better understand lung cancer and the treatment options that are available.

Lung Cancer. This reference summary will help you better understand lung cancer and the treatment options that are available. Lung Cancer Introduction Lung cancer is the number one cancer killer of men and women. Over 165,000 people die of lung cancer every year in the United States. Most cases of lung cancer are related to cigarette

More information