Chromeleon 7. Operational Simplicity for the Laboratory

Transcription

1 Chromeleon 7 Operational Simplicity for the Laboratory

2 Topics Introducing Chromeleon 7 User Interface Peak Detection Tools eworkflows Interactive Charting Reporting Support for Third Party Instrumentation Summary

3 Introducing Chromeleon 7 New-generation Chromatography Data System Simply Intelligent Intelligent Functionality - it does everything you need! Operational Simplicity - everything is fast and easy! Simplifies all chromatography processes

4 Chromeleon 7 - Operational Simplicity Operational Simplicity was the core design principle Major design rules: Minimize number of steps needed to perform any task Make all steps easy to understand and easy to use Minimize time needed to perform any task Major features for Operational Simplicity: Modern user interface Peak detection and integration tools eworkflows Data visualization tools Enterprise functionality

5 USER INTERFACE

6 User Interface The Chromeleon User Interface consists of two major parts: Chromeleon Console Chromatography Studio

7 Chromeleon Console Designed to provide easy navigation through your data Provides quick access to: Instruments Data eworkflows

8 Console Quick Access to Information Navigation Pane Category Bars 8

9 Thumbnails Quick Access to Data Quick check to see if chromatogram ran properly Check for presence / absence of peaks Check quality of separations

10 Instruments - epanels Provides access to all instruments on the network Direct Control of Instrument through controls on epanel

11 Chromatography Studio Used for All Data Evaluation Provides access to every object in the sequence: Injection List Instrument Method Processing Method Results Report Template Spectral Library Opens in separate window on task bar makes working with multiple sequences easy Uses new Ribbon technology introduced in Microsoft Office 2007

12 Chromatography Studio Ribbon Navigation Pane Category Bars

13 New Ribbon Interface Provides contextual access to commands and options in the Studio 13

14 PEAK DETECTION COBRA Detection Algorithm / SmartPeaks

15 Peak Detection Most time consuming and tedious task in chromatography process: Chromatogram Integration Chromeleon 7 introduces two new tools to simplify this process: Cobra Peak Detection Algorithm / Wizard SmartPeaks Integration Assistant

16 Peak Detection Cobra Cobra is a new algorithm that: Finds peak start and end times accurately and consistently Requires minimum number of parameters to reach integration goals Cobra Wizard provides: Fast, guided way to determine initial detection parameters

17 Peak Detection Cobra Wizard

18 Peak Detection Cobra Wizard Start Cobra Wizard Define the integration range Select the narrowest peak to be integrated Select the smallest peak to be integrated

19 Peak Detection Cobra Wizard And your integration is done! 19

20 Peak Detection - SmartPeaks Unique tool for easily reaching your integration goals for unresolved peaks Requires no training Great example of Operational Simplicity Process is clear and understandable Requires only a few steps Correctly integrates all unresolved peaks in seconds

21 Peak Detection SmartPeaks Activate SmartPeaks Wizard Select area of interest Select the integration you want 21

22 Peak Detection SmartPeaks And your integration is done! 22

23 eworkflows The Ultimate in Operational Simplicity

24 eworkflows eworkflows automate all chromatography processes Applies to all laboratories, for example: QA/QC laboratories Method development laboratories Research & Development laboratories Walk-up instrument workflows Takes you from Samples to Results in only a few steps

25 eworkflows An eworkflow brings together all aspects of a chromatography run: Instruments which are allowed to run this application All associated files: Instrument Methods Processing Methods Reports Spectral Libraries Documents with description of method Template for sequence name and storage location Custom Variables Rules for sequence layout

26 eworkflows A Regulated USP/EP Method Sequence is created and can be immediately run Choose eworkflow, select instrument, and click Start Enter number of samples, and start position

27 eworkflows A Regulated USP/EP Method This eworkflow also: Processes all data Calculates all results

28 eworkflows From Samples to Results eworkflows take you from Sample to Results in the minimum number of steps Fully customizable for any application Minimum amount of training required Reduces errors and produces results faster A new framework for Operational Simplicity

29 INTERACTIVE CHARTING

30 Data Visualization Interactive Charts for Data Visualization Fully customizeable Templates for the most common tasks Available for both on-screen and printed/exported reports.

31 Interactive Charting Various Chart types Pie Chart 2D / 3D Stacked Column 2D / 3D Scatter Plot

32 Interactive Charting: Examples Product Stability Query performed on SQL Server database on all data (including historical) Active Rel.Area % vs. Impurity Rel.Area %.

33 Interactive Charting: Examples Instrument Utilization 33

34 Interactive Charting: Examples Column Performance 34

35 REPORTING

36 Spreadsheet Based Reporting The Excel-like report environment is both familiar and intuitive. If Excel is used for additional calculations they can be included in Chromeleon. No data transcription or export to Excel is required. Results are generated instantly.

37 Spreadsheet Based Reporting Excel-like formulae can be included for custom calculations In this case the operator has configured a report to flag out of specification results.

38 Report Designer - Functions Many Excel-like functions available use identical syntax AVERAGE IF / AND / OR STDEV COUNT SUM LOOKUP etc

39 Report Designer Export Options 1. TXT 2. PDF 3. XLS

40 SUPPORT FOR THIRD PARTY INSTRUMENTS

41 Instrument Control Chromeleon 7 can control Thermo Scientific LC, GC and IC. Chromeleon 7 can control 3rd Party LCs and GCs Agilent 1100, 1200, 1260, 1290, G1888, 6850, 6890, 7890 Waters Acquity, Alliance Shimadzu LC10, LC2010, LC20 Chromeleon 6.8 controls over 330 different modules from 30 different manufacturers. These drivers are being converted to CM7

42 Interfacing with 3rd Party Instruments Formal Code Exchange agreements with major manufacturers: Waters Agilent CTC Shimadzu For other manufacturers we rely on openly published codes e.g. GSIOC codes for Gilson systems For some manufacturers we provide a Driver Development Kit Merck Hitachi 42

43 SUMMARY

44 Chromeleon 7 Simply Intelligent Contains the Intelligent Functionality needed to generate the result! Uses Operational Simplicity to minimize the steps and time needed to generate the result! Offers state-of-the-art technology: User Interface with Ribbon COBRA Peak Detection Algorithm & Wizard SmartPeaks Integration Assistant eworkflows THE framework for Operational Simplicity Advanced Interactive Charting Advanced Reporting Permits control of multiple vendors equipment from one application.

45 Chromeleon 7 Simply Intelligent Questions?