KitoZyme. EUROTRANS-BIO/ EUROSTAR Project calls Experience from SME Véronique MAQUET Product Dvt Manager-KitoZyme

Transcription

1 KitoZyme EUROTRANS-BIO/ EUROSTAR Project calls Experience from SME Véronique MAQUET Product Dvt Manager-KitoZyme

2 KitoZyme Production High purity chitosan and chitin-glucan Exclusively from renewable, non-gmo vegetal sources Patented sustainable technology Innovative, efficient, high added-value and safe Active in four strategic markets Nutraceuticals (KiOnutrime ) Cosmetics (KiOsmetine ) Beverage (KiOfine ) Pharmaceuticals and medical (KiOmedine ) 2

3 KitoZyme Founded in 2000 Based in Hertsal (BE) 4000m² production area 150m² cgmp production unit 3 production lines A highly-skilled team of 50 employees 6 PhDs and 7 Engineers 10 staff with expertise in health and polymer science 4 staff dedicated to the valorisation of the know-how and patent portfolio 10 patents An international network of academic and industrial partners n 3

4 KitoZyme: Current Project Portfolio Acronym Call Title Coordinator CODE EUROSTAR Adhesive silicone hydrogel for Controlled Oral Drug Elution Biomodics, Denmark HOLLOWKIT ERANETEurotransbio Optimized biodegradable tubular bioprosthesis made of chitosan for the repair of esophageal defects KitoZyme (4th call) PARTIKIT PRESTIGE REBORNE SONO TARGETUM WAL-AID EUROSTAR FP7-HEALTH FP7-HEALTH FP7- NMP-2008 BIOWIN WAGRALIM Particules de chitosane à morphologie contrôlée en tant que système mucoadhésif pour la libération d allergènes Prevention of late Stent Thrombosis by an Interdisciplinary Global European Effort Peter Thomsen Véronique Maquet KitoZyme Véronique Maquet DHM (DE) Regenerating Bone defects using New biomedical Engineering approaches INSERM (Nantes, FR) A pilot line of antibacterial and antifungal medical textiles based on a sonochemical process Bar Ilan University (Israel) Pierre Layrolle Aharon Gedanken Systèmes de délivrance ciblée d agents thérapeutiques basés sur l utilisation de chitosane : KitoZyme - Du concept à la preuve de faisabilité Audrey DESCHAMPS Compétitivité et durabilité des filières d'industries agroalimentaires wallonnes par la constitution d'une plateforme interdisciplinaire d expertises pour le reprocessing de leurs flux connexes CONFIDENTIAL - Copyright November 2009 KitoZyme Olivier BAUM 4

5 KiOmedine -CsU Origin Fungal = Agaricus bisporus; edible mushroom, secured large-scale European source Patent Patented & validated process, outstanding traceability, 100% animalfree Quality system Products Pharmaceutical grade, ICH-Q7 ISO7/ISO8 facilities, in line with cgmp, including IPEC-PQG GMP guidelines for Pharmaceutical Excipients Ultra-pure chitosan, ultra-pure watersoluble chitosan derivatives, formulations Strong manufacturing & safety documentation, master file in CTD format, DMF in preparation Documentation Use Suitable for all medical devices classes & routes of administration of drugs (incl. class III implants & injectables, processing, analytical studies, etc Reliable characteristics Batch-to-batch consistency & tight control of molecular CONFIDENTIAL - Copyright November 2009 characteristics, substantially equivalent to shellfish chitosan KitoZyme All rights reserved 5

6 KiOmedine-CsU - Chemical Characteristics Safe & non toxic: minimal inflammatory response and foreign body reaction GAG structure similar to the ECM : good cell substrate, elicitor of ECM expression and stimulation of new tissue formation provide cells with an hydrated environment, permeable to oxygen and nutriments for cell survival ability to accelerate wound healing Biodegradable Haemostatic Muco/bioadhesive (ability to adhere to skin/mucosa) Antibacterial/antimicrobial Can be easily processed into different forms, porous structures> good scaffolding material 6

7 HOLLOWKIT project EUROTRANS-BIO: 4th transnational call Optimized biodegradable tubular bioprosthesis made of chitosan for the repair of esophageal defects Duration: 30 mths- Starting June 1, 2010 Total budget: Consortium : Project Coordinator: KitoZyme (BE) Partner: mfd Diagnostics GmbH (DE) Subcontractors: Véry COULIC (BE) Bio.be (BE) Sterigenics (BE) SGS-Life Science (BE) Medovent (DE) 7

8 PARTIKIT project EUROSTAR Particules de chitosane à morphologie contrôlée en tant que système mucoadhésif pour la libération d'allergènes Duration: 30 mths- Starting October 1, 2010 Budget: Consortium : Project Coordinator: KitoZyme (BE) Partner: o EmulTech BV (Pays-Bas) o Stallergenes (France) Subcontractors: ULg Pharma ULg- CERM 8

9 Experience of the calls EUROTRANS- BIO EUROSTAR Consor&um size Ideal for small consor&um Ideal for small consor&um Submission Submission to ETB- office is convenient Submission to EUREKA secretariat is convenient Project evalua&on Short &me Short &me Funding rules 80% for SME (in BE).But 70% for SME (in BE) disparity between funding rules in different countries, i.e. 50% in DE Repor&ng Periodic reports to be submiued to DG06 Periodic reports to be submiued to DG06 and to EUREKA secretariat 9

10 Thank you for your attention!