VWR Autosampler Vials, Inserts and Closures. When Reliability is Key

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1 VWR Autosampler Vials, Inserts and Closures When Reliability is Key

2 The WebSeal System WebSeal System has the most comprehensive range of covers for all micro titer plate configurations. The WebSeal closure system reseals around the needle even after multiple aliquots have been taken preventing sample loss. Vials from 500 µl to 1.5 ml capacity for both 96 round and square well plates can be used with the WebSeal covers. Convenient wellplate kits with pre-inserted glass or PTFE vials Replacement vials for kits available separately Unique cutting tool allows removal of individual samples with the seal in place, eliminating cross contamination Kits are packaged with vials pre-assembled along with a pack of 5 wellplate covers NEW 96 Wellplate with 650 µl tapered glass vials pre-inserted, 5 mats and cutting tool 96 Wellplate with 1.1 ml crimp top vials pre-inserted, 5 mats and cutting tool 96 Well plate with 650 µl tapered PTFE vials pre-inserted, 5 mats and cutting tool Cutting tool Replacement Vials 96 Wellplate 650 µl tapered glass replacement vials 96 Wellplate 1.1 ml crimp top replacement vials 96 Wellplate 650 µl tapered PTFE replacement vials WebSeal Mats Manufactured from PTFE coated silicone Superior resealability up to 100 injections Eliminates cross contamination of samples Dry heat autoclavable with excellent chemical compatibility 96 Round well dome based WebSeal mats Round well flat based WebSeal mats Square well dome based WebSeal mats Square well flat based WebSeal mats Round well flat based WebSeal mats Square well flat based WebSeal mats

3 Welcome to the VWR Chromatography brochure. This brochure represents the complete line of VWR autosampler vials and accessories offered. Vial choices include: screw top, crimp/snap, headspace and speciality vials with a large selection of closures. Refer to the Autosampler Compatibility Table on pages 18 and 19 to determine which vials, closures and inserts will work on your specific autosampler unit. VWR Certified Vial Convenience kits VWR is excited to introduce NEW Certified Vial Convenience kits that come complete with vials, closures and a certificate of conformance. These kits offer the extra quality assurance that time after time the vials and closures will perform at a superior level. Bonded caps prevent septum slippage during needle penetration. With a comprehensive product offering, multiple instruments can be accommodated using VWR Certified Kits NEW Certificate of Conformance in every pack Fully lot tested including GC and HPLC analysis Bonded caps prevent septa push-through Compatible with every autosampler 1.8 ml Clear Glass with Marking Spot and mm Bonded PTFE/Silicone closure 1.8 ml Clear Glass with Marking Spot and mm Bonded Pre-Slit PTFE/Silicone closure 1.8 ml Amber Glass with Marking Spot and mm Bonded PTFE/Silicone closure 1.8 ml Amber Glass with Marking Spot and mm Bonded Pre-Slit PTFE/Silicone closure 1.5 ml High Recovery Clear Glass Vial with Gray cap Bonded PTFE/Silicone pre-slit septa 1.5 ml High Recovery Clear Glass Vial with Black cap Bonded PTFE/Silicone septa 1.8 ml Clear Glass Vial with Blue cap PTFE/Silicone septa 900 µl Precision Taper Clear Glass Vial with Black cap Bonded PTFE/Silicone septa 3

4 1.8 ml 12 x 32 mm Standard Opening Crimp Vials and Closures 11 mm Aluminum Seal Finish Standard opening 12 x 32 mm vials with 11 mm aluminum seal finishes. Clear vials are made from Type 1, Class A, borosilicate glass. Amber vials are made from 51A amber borosilicate glass. Available with or without marking spots. For Agilent, Hitachi, PerkinElmer, Shimadzu, Varian and Waters autosamplers. 1.8 ml Clear Glass ml Clear Glass with Marking Spot ml Amber Glass ml Amber Glass with Marking Spot VWR 11 mm Aluminum Seals Aluminum Seals provide secure closures even when using volatile solvents. PTFE/Natural Red Rubber PTFE/Silicone Red PTFE/Silicone / Red PTFE mm Inserts VWR offers a complete line of inserts for your microsampling needs, specifically engineered for use with our standard opening aluminum seal vials. 0.2 ml Conical, Glass with Spring ml Conical, Glass ml Flat Bottom, Glass ml Large Opening Crimp Vials and Closures 12 x 32 mm VWR Specialty Vials 12 x 32 mm Crimp Vials for applications where available sample volume is limited. 250 µl Fused Insert Vial, Clear with Marking Spot µl Fused Insert Vial, Amber with Marking Spot µl Polypropylene Vial VWR Convenience Kits Each kit contains 1.8 ml clear glass vials and aluminum seals in one easy to use package. PTFE/Synthetic Red Rubber Seal PTFE/Natural Red Rubber Lined Seal PTFE/Silicone Lined Seal Red PTFE/Silicone/Red PTFE Lined Seal

5 1.8 ml Large Opening Crimp Vials 12 x 32 mm VWR 11 mm Crimp Vials 12 x 32 mm vials feature 40% larger openings and 11 mm aluminum seal finishes. Clear vials are made from Type 1, Class A, borosilicate glass. Amber vials are made from 51A amber borosilicate glass. 1.8 ml Clear Glass ml Clear Glass with Marking Spot ml Amber Glass ml Amber Glass with Marking Spot mm Aluminum Seals Alumninum Seals provide secure closure even when using volatile solvents. These seals fit all 11 mm crimp vials. PTFE/Synthetic Red Rubber Seals offer improved performance through lower background extractables. PTFE/Natural Red Rubber Liner PTFE/Silicone Liner Red PTFE/Silicone/Red PTFE Liner PTFE/Synthetic Red Rubber, Silver Inserts, 6 mm VWR offers a complete line of inserts for your microsampling needs, specifically engineered for use with our Large Opening vials ml Conical, Glass with spring ml Conical, Polypropylene w/spring ml Conical, Glass ml Flat Bottom, Glass ml Flat Bottom, Polypropylene Call the VWR Chromatography Hotline VWR-LINE (option 2) 5

6 1.8 ml Large Opening Crimp/Snap Vials 12 x 32 mm For use with 11 mm Snap Caps or 11 mm Aluminum Seals Vials feature 40% larger openings and 11 mm Aluminum Seal Crimp / Snap-Ring finishes. Clear vials are made from Type 1, Class A, borosilicate glass. Amber vials are made from 51A amber borosilicate glass. For Agilent, Hitachi, PerkinElmer, Shimadzu, Varian and Waters autosamplers. 1.8 ml Clear Glass ml Clear Glass with Marking Spot ml Amber Glass ml Amber Glass with Marking Spot mm Snap Caps for Crimp/Snap-Ring LOVials Snap Cap closures provide a secure seal for all but the most volatile solvents. Snap Caps are easy to apply and easy to remove with no tools. PTFE/Red Rubber, Natural PTFE/Silicone, Natural Pre-Slit PTFE/Silicone, Natural VWR Convenience Kits. Each kit contains 1.8 ml clear glass vials and snap cap closures in one easy to use package. PTFE/Red Rubber Snap Cap Closure Red PTFE/Silicone Snap Cap Closure

7 8 x 40 mm Shell Vials and Closures 8 x 40 mm shell vials are made from low extractable borosilicate glass. These 1 ml vials are designed for use with Waters 96-Position trays 1 ml Clear with Natural Closure ml Amber with Natural Closure Sample pack of VWR vials and closures x 35 mm Positive Displacement Vials 8 x 35 mm vial is made from Type 1, N51A clear borosilicate glass for use on Alcott autosamplers ml Clear Glass with Plug

8 1.8 ml Standard Opening Screw Thread Vials, Thread Finish, 12 x 32 mm Standard opening screw thread vials feature an thread finish. Clear vials are made from Type 1, Class A, borosilicate glass. Amber vials are made from 51A amber borosilicate glass. Available with or without marking spots. For Hitachi, PerkinElmer, Shimadzu, Varian and Waters 2690 autosamplers. 1.8 ml Clear Glass ml Clear Glass with Marking Spot ml Amber Glass ml Amber Glass with Marking Spot Pre-Assembled Open Top Closures with Septa, Flanged caps are designed to fit Japanese autosampler trays. They are also compatible with many other instruments--see the Autosampler chart on pages 18 & 19 for more details. Black Phenolic, Red PTFE/Silicone Black Polypropylene, Red PTFE/Silicone mm Inserts 5 mm inserts fit securely into standard opening vials. Springed Conical inserts are self centering and provide a cushion against needle penetration. 0.2 ml Conical, Glass with Spring ml Conical, Glass ml Flat Bottom, Glass VWR Convenience Kits Convenience kits make ordering easy. Each kit contains vials and pre-assembled closures in one easy to use package. Select closure type from the table below. All kits listed below come with 1.8 ml Clear Glass vials and Screwthread Closures. Red PTFE/Silicone with Phenolic closure Red PTFE/Silicone with Polypropylene closure VWR Pre-assembled Vial Kits Each kit contains 1.8 ml clear glass vials with attached screwthread closures. Red PTFE/Silicone with Phenolic closure Red PTFE/Silicone with Polypropylene closure

9 1.8 ml Screw Thread Finish Vials, 12 x 32 mm Consolidate your lab with the one autosampler vial that does it all. The robotic vial offers the convenience of a large opening screw thread and a profile specifically designed for robotic arm autosamplers. Clear vials are made from Type 1, Class A, borosilicate glass. Amber vials are made from 51A amber borosilicate glass. For Agilent, PerkinElmer, Varian and Waters 2690 autosamplers. VWR Screw Thread Vials 1.8 ml Clear glass, ml Clear glass with Marking spot, ml Amber glass, ml Amber glass with Marking spot, Pre-Assembled Color Coded Closures with Septa PTFE/Red Rubber, Black Cap PTFE/Silicone, Black Cap PTFE/Silicone / PTFE, Black Cap Pre-Slit PTFE/Silicone, Black Cap mm Inserts VWR offers a complete line of inserts for your microsampling needs, specifically engineered for use with these vials ml Conical, Glass with spring ml Conical, Polypropylene w/spring ml Conical, Glass ml Flat Bottom, Glass ml Flat Bottom, Polypropylene VWR Convenience Kits Each kit contains 1.8 ml clear glass vials and screw thread closures in one easy to use package. All kits come with 1.8 ml Clear Glass vials PTFE/Red Rubber with Polypropylene closure Red PTFE/Silicone / Red PTFE with Polypropylene closure Red PTFE/Silicone with Polypropylene closure VWR Pre-assembled Vial Kits Each kit contains 1.8 ml clear glass vials with attached screwthread closures. PTFE/Red Rubber with Polypropylene closure Red PTFE/Silicone / Red PTFE with Polypropylene closure Red PTFE/Silicone with Polypropylene closure

10 1.8 ml Wide Opening Screw Thread Vials, 12 x 32 mm, VWR Wide Opening Screw Thread Vials, 12 x 32 mm, Screwthread vials feature a 40% larger opening for easier sample filling. Clear vials are made from Type, 1 Class A, borosilicate glass. Amber vials are made from 51A amber borosilicate glass. Available with or without marking spots. 1.8 ml Clear glass, ml Clear glass with Marking spot, ml Amber glass, ml Amber glass with Marking spot, VWR Pre-Assembled Open Top Closures with Septa, Black Polypropylene, PTFE/Silicone Black Polypropylene, Pre-slit PTFE/Silicone ml Screw Thread Vials for Waters 48-Position and Shimadzu, Thread Finish These 4 ml, 15 x 45 mm screw thread vials feature a thread finish and are made from Type 1, Class A, borosilicate glass. Available in clear or amber glass, with or without a marking spot. For Shimadzu, Waters and other autosamplers fitted with 15mm diameter opening trays. VWR Screw Thread Vials 4 ml Clear glass ml Clear glass with Marking spot ml Amber glass ml Amber glass with Marking spot VWR Pre-Assembled Open Top Closures with Septa, Red PTFE/Silicone, Polypropylene, Pre-Slit PTFE/Silicone, Polypropylene, White cap Red PTFE/Silicone, Phenolic, VWR Convenience kit w/ Pre-assembled Closure Kit contains 4 ml Clear glass vial Red PTFE/Silicone w/ Polypropylene Closure VWR Pre-Assembled Vial kit Each kit contains 4 ml clear glass vials and screw thread closures in one easy to use package. Red PTFE/Silicone with Polypropylene Closure

11 Magnetic Headspace Vials and Caps NEW Now available in both crimp and screw top headspace vials the magnetic caps are compatible with CTC/LEAP and GERSTEL instruments. Composite bi-metal magnetic crimp caps for easy crimping and decapping. A wide variety of septa are available for every headspace analysis. Magnetic Crimp Caps Aluminum skirt on bi-metal caps provide easy crimping Tin plate center for magnetic pick up 8mm center opening provides large target area and easy inspection of septum Internal rim contoured to conform to the beveled edge of the vial for secure seal Magnetic Screw Caps Preassembled closures minimize contamination during sample preparation PTFE/silicone septa is a thin, soft durometer seal designed for SPME applications 10 ml Clear Glass Round Bottom Screw Thread Headspace Vial 20 ml Clear Glass Round Bottom Screw Thread Headspace Vial 18 mm Magnetic Screw Cap with molded natural PTFE/blue silicone septa 18 mm Magnetic Screw Cap with cut disk white PTFE/blue chlorobutyl septa 18 mm Magnetic Screw Cap with soft durometer white PTFE/blue silicone septa 20 ml Clear Glass vial and blue magnetic combi-seal with PTFE/silicone septa (kit) 20 ml Clear Glass vial and silver tine magnetic cap with PTFE/Butyl Pharma-Fix septa (kit) Call the VWR Chromatography Hotline VWR-LINE (option 2) 11

12 Let VWR Lighten Your Load! VWR International now offers you unrivaled access to the world's leading suppliers of Chromatography products and services. Our list of manufacturers and suppliers reads like a 'who's who' of the Chromatography and Filtration Industries Agilent Technologies, Beckman Coulter, Biotage, EMD Chemicals, ES Industries, Hamilton, Mallinckrodt Baker, Merck KGaA, National Scientific, Optimize, Pall Life Sciences, SGE, Spectrum Laboratories, Sun SRI, 3M, Upchurch, Restek, Whatman, Wheaton and dozens more! Working closely with our world-class suppliers and VWR's general sales force is our field-based team of dedicated Chromatography Specialists. With more than 100 years of combined lab expertise, they're ready to provide support for your chromatography applications and answer your sample prep questions. We ll help you with your heavy decisions, choosing the right LC and GC columns and selecting from our comprehensive offering of unique and alternative accessories, supplies and repair parts from our just released VWR Chromatography & Filtration Catalog. Our in-house telephone tech support specialists will provide the quick answers you often need to those urgent questions that threaten to disrupt your busy day. Let VWR help ease the strain. Contact the hotline at VWR-LINE (option 2 for Chromatography/Filtration). For more information, call or visit 12

13 Custom Cleaning Services Custom Cleaning We have the flexibility to meet your cleaning requirements, whether your cleaning needs are for high volumes or smaller quantities. We have the capability to clean clear/amber glass or plastic containers, as well as closures or other component parts. Send us your containers and closures, or purchase from our extensive line of standard and custom products. We can process containers from 100 µl to 20 L. All cleaning services and packaging can be done in our certified class 100/10 cleanroom with full traceability and GMP compliance. 13

14 Custom Cleaning Services Silanization Services Our line of ready-to-use silanized vials, culture tubes and autosampler inserts, save valuable time and minimize costs when performing quantitative analysis or storing materials. Applications: Trace organic analysis Storage of materials prone to adhering to glass Extraction glassware Siliconization Service Siliconized products are physically coated with a medical-grade silicone emulsion to prevent sample material from reacting with the glass container. Applications: Proteins Assays of blood serum Pharmacological assays of therapeutic drugs Silanization how do we do it? A methysilylating agent is introduced by vapor phase deposition onto the surface of the disposable glassware. The silylating agent reacts with active groups on the surface of the glass effectively tying up these sites so they are less reactive. This treatment inhibits materials from adhering onto the surface of the container, allowing for maximum recovery of trace analyte. Clean Room Process Irradiation Sterile foil-wrap Steam sterilization Depyrogenation Silanization Siliconization Injectable or parenteral drugs Lyophilization Final packaging prior to drug delivery Stability studies Clinical trials Proteins Assays of blood serum Pharmacological asays of therapeutic drugs 14

15 Custom Cleaning Services Depyrogenated Glass/Depyrogenation Service VWR provides glass vials and other containers that have been specially prepared to meet endotoxin levels of less than 0.06 EU/mL. A variety of sizes are available. Depyrogenated vials and containers may also be requested with additional certifications. VWR can depyrogenate any glass as a service. The process uses dry heat at 250 degrees Celsius for a minimum of two and one half-hours. Cleaning and packaging is performed inside a Class 100 cleanroom. Applications: Non-parenteral uses such as water sampling and testing of endotoxins. Storage of packaging of terminally sterilized articles. Storage of lab reagents and media Sterilization Services We offer a number of sterilization services to effectively destroy all viable forms of life, including bacterial spores to a sterility assurance level (SAL) of 106. Services include gamma irradiation, dry-heat, autoclave or e-beam. Applications: Injectable or parental drugs Lyophilization Final packaging prior to drug delivery Stability studies Clean Process Vials Low Carbon (TOC) Vials We offer low-level certified vials for Total Organic Carbon testing and sampling. Major TOC instrument manufacturers use and recommend our vials. We offer several sizes of containers including the popular 40 ml autosampler vials cleaned, certified and ready to use. Each lot of vials is tested and certified to contribute no more than 10 ppb TOC as background. Certificate of Analysis included. Off-line and gram sampling of high autosamplers Low background is perfect for preparation and storage of standards Cleaning validation is simplified and costs are reduced by using the TOC method of testing Sterile Empty Vials Certified depyrogenated and sterile vials are available in sizes from 1 ml to 100 ml. Sterile vials are Type 1 borosilicate, assembled with butyl stoppers and aluminum seals. Sterilization is performed in a FDA licensed facility, practicing GMPs. Suitable for a number of uses where aseptic protocol is required Sterile Vials clear finish, pyrogen tested with certificate of sterility Customized analytical parameters may include special GC, GC/MS, ICP/MS, ICP, AA, GF-AA or other testing. 15

16 Clean Process Containers Low-Particle Containers VWR vials and containers are certified to contain fewer than 5 particles per milliliter larger than 0.5 microns. This exceeds the USP <788> specifications for particle content of containers. Cleaning and packaging is performed inside a Class 100 cleanroom. Class 100, double bagged glass bottles are assembled with low-shedding, polypropylene caps with chemically inert PTFE faced liners that do not contain adhesives. Storage and packaging of chemicals, reagents, powders etc. Excellent for preparation and storage of standards Double-bagged to ensure no contaminates are introduced to the clean room Off-line deionized water and chemical sampling for particle analysis Amber glass protects light-sensitive chemicals Ready for sterilization The United States Pharmacopeia issued new guidelines in Method 643 making TOC analysis mandatory. The modification as published in the Fifth Supplement to the USP/NF 23 states that the glassware to be used must be scrupulously cleaned of organic matter to reduce contamination. Our TOC vials are prepared by a proprietary method to reduce background contamination to less than 10ppb TOC. Certificate of Analysis included with all custom processes 16

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